WO1992011370A3 - Polypeptides derives de proteines du virus de l'hepatite c - Google Patents
Polypeptides derives de proteines du virus de l'hepatite c Download PDFInfo
- Publication number
- WO1992011370A3 WO1992011370A3 PCT/DE1991/001020 DE9101020W WO9211370A3 WO 1992011370 A3 WO1992011370 A3 WO 1992011370A3 DE 9101020 W DE9101020 W DE 9101020W WO 9211370 A3 WO9211370 A3 WO 9211370A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hepatitis
- virus
- polypeptides
- proteins
- polypeptides derived
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 241000711549 Hepacivirus C Species 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 101710132601 Capsid protein Proteins 0.000 abstract 1
- 238000003149 assay kit Methods 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 230000004962 physiological condition Effects 0.000 abstract 1
- 238000012163 sequencing technique Methods 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/078,271 US6136527A (en) | 1990-12-21 | 1991-12-20 | Polypeptides derived from proteins of the hepatitis C virus, test kits containing these polypeptides and vaccines against infections of hepatitis C viruses |
AT92902118T ATE270333T1 (de) | 1990-12-21 | 1991-12-20 | Von proteinen des hepatitis c-virus abgeleitete polypeptide und deren verwendung |
DE59109261T DE59109261D1 (de) | 1990-12-21 | 1991-12-20 | Von proteinen des hepatitis c-virus abgeleitete polypeptide und deren verwendung |
EP92902118A EP0564532B1 (fr) | 1990-12-21 | 1991-12-20 | Polypeptides derives de proteines du virus de l'hepatite c |
JP4502438A JP2598596B2 (ja) | 1990-12-21 | 1991-12-20 | C型肝炎ウイルスの蛋白質に由来するポリペプチド、該ポリペプチドを含有するテストキットおよびc型肝炎ウイルス感染予防ワクチン |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEP4041304.7 | 1990-12-21 | ||
DE4041304A DE4041304A1 (de) | 1990-12-21 | 1990-12-21 | Von strukturproteinen des hepatitis c-virus abgeleitete polypeptide, testkits, die diese polypeptide enthalten und impfstoffe gegen infektionen von hepatitis c-viren |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1992011370A2 WO1992011370A2 (fr) | 1992-07-09 |
WO1992011370A3 true WO1992011370A3 (fr) | 1992-10-29 |
Family
ID=6421107
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE1991/001020 WO1992011370A2 (fr) | 1990-12-21 | 1991-12-20 | Polypeptides derives de proteines du virus de l'hepatite c |
Country Status (7)
Country | Link |
---|---|
US (1) | US6136527A (fr) |
EP (1) | EP0564532B1 (fr) |
JP (2) | JP2598596B2 (fr) |
AT (1) | ATE270333T1 (fr) |
DE (2) | DE4041304A1 (fr) |
ES (1) | ES2222453T3 (fr) |
WO (1) | WO1992011370A2 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1249684B (it) * | 1991-07-19 | 1995-03-09 | Sorin Biomedica Spa | Epitopi della proteina env del virus dell'epatite c. |
JP2778886B2 (ja) * | 1992-10-16 | 1998-07-23 | エバーニュー バイオテック インコーポレイティド | C型肝炎ウィルスのコア抗原タンパク質及びそれを用いての診断方法及びキット |
US6153378A (en) * | 1992-10-16 | 2000-11-28 | Bionova Corporation | Diagnosis of, and vaccination against, a positive stranded RNA virus using an isolated, unprocessed polypeptide encoded by a substantially complete genome of such virus |
US5514539A (en) * | 1993-06-29 | 1996-05-07 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines |
DE4428705A1 (de) | 1994-08-12 | 1996-02-15 | Boehringer Mannheim Gmbh | Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus |
GB9513261D0 (en) * | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
CA2503303A1 (fr) * | 2002-11-08 | 2004-05-27 | The Administrators Of The Tulane Educational Fund | Inhibiteurs de fusion du flavivirus |
WO2008046923A2 (fr) * | 2006-10-20 | 2008-04-24 | Innogenetics N.V. | Méthode d'analyse de variations de séquence dans une zone génomique ns3/4a du vhc |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0388232A1 (fr) * | 1989-03-17 | 1990-09-19 | Chiron Corporation | Diagnostics et vaccins de NANBV |
EP0450931A1 (fr) * | 1990-04-04 | 1991-10-09 | Chiron Corporation | Combinaisons d'antigènes de l'hépatitis C virus (HCV) pour usage dans des échantillons immunologiques pour anticorps anti-HCV |
EP0464287A1 (fr) * | 1990-06-25 | 1992-01-08 | The Research Foundation for Microbial Diseases of Osaka University | cADN génomique du virus de l'hépatite non-A non-B et antigène polypeptidique |
EP0468657A2 (fr) * | 1990-07-09 | 1992-01-29 | Tonen Corporation | Antigène spécifique de l'hépatite non-A, non-B et son utilisation pour le diagnostic de l'hépatite |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5350671A (en) * | 1987-11-18 | 1994-09-27 | Chiron Corporation | HCV immunoassays employing C domain antigens |
-
1990
- 1990-12-21 DE DE4041304A patent/DE4041304A1/de not_active Withdrawn
-
1991
- 1991-12-20 DE DE59109261T patent/DE59109261D1/de not_active Expired - Fee Related
- 1991-12-20 JP JP4502438A patent/JP2598596B2/ja not_active Expired - Fee Related
- 1991-12-20 AT AT92902118T patent/ATE270333T1/de not_active IP Right Cessation
- 1991-12-20 EP EP92902118A patent/EP0564532B1/fr not_active Expired - Lifetime
- 1991-12-20 WO PCT/DE1991/001020 patent/WO1992011370A2/fr active IP Right Grant
- 1991-12-20 US US08/078,271 patent/US6136527A/en not_active Expired - Fee Related
- 1991-12-20 ES ES92902118T patent/ES2222453T3/es not_active Expired - Lifetime
-
1995
- 1995-10-23 JP JP7274510A patent/JPH08275781A/ja active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0388232A1 (fr) * | 1989-03-17 | 1990-09-19 | Chiron Corporation | Diagnostics et vaccins de NANBV |
EP0450931A1 (fr) * | 1990-04-04 | 1991-10-09 | Chiron Corporation | Combinaisons d'antigènes de l'hépatitis C virus (HCV) pour usage dans des échantillons immunologiques pour anticorps anti-HCV |
EP0464287A1 (fr) * | 1990-06-25 | 1992-01-08 | The Research Foundation for Microbial Diseases of Osaka University | cADN génomique du virus de l'hépatite non-A non-B et antigène polypeptidique |
EP0468657A2 (fr) * | 1990-07-09 | 1992-01-29 | Tonen Corporation | Antigène spécifique de l'hépatite non-A, non-B et son utilisation pour le diagnostic de l'hépatite |
Non-Patent Citations (3)
Title |
---|
Japanese Journal of Experimental Medicine, Band 60, Nr. 4, 1990 (Tokyo, JP) H. Okamoto et al.: "Enzyme-linked immunosorbent assay for antibodies against the capsid protein of hepatitis C virus with a synthetic oligopeptide", Seiten 223-233, siehe Seiten 223-233 * |
Nucleic Acids Research, Band 18, Nr. 15, August 1990, Oxford University Press (Oxford, GB) K. Takeuchi et al.: "Nucleotide sequence of core and envelope genes of the hepatitis C virus genome derived directly from human healthy carriers", Seite 4626 * |
Peptide Chemistry 1990, Proceedings of the 28th Symposium on Peptide Chemistry, Osaka, 25-27 Oktober 1990, E. Munekata et al.: "Epitope-mapping of hepatitis C virus constituting protein", Seiten 211-214, siehe Seiten 211-214 * |
Also Published As
Publication number | Publication date |
---|---|
JPH06502542A (ja) | 1994-03-24 |
JP2598596B2 (ja) | 1997-04-09 |
US6136527A (en) | 2000-10-24 |
EP0564532B1 (fr) | 2004-06-30 |
DE4041304A1 (de) | 1992-06-25 |
WO1992011370A2 (fr) | 1992-07-09 |
DE59109261D1 (de) | 2004-08-05 |
ES2222453T3 (es) | 2005-02-01 |
EP0564532A1 (fr) | 1993-10-13 |
JPH08275781A (ja) | 1996-10-22 |
ATE270333T1 (de) | 2004-07-15 |
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