WO1990004977A3 - Traitement de condylomes genitaux a l'aide d'une combinaison d'azote liquide et d'interferon alpha humain d'adn de recombinaison - Google Patents

Traitement de condylomes genitaux a l'aide d'une combinaison d'azote liquide et d'interferon alpha humain d'adn de recombinaison Download PDF

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Publication number
WO1990004977A3
WO1990004977A3 PCT/US1989/004766 US8904766W WO9004977A3 WO 1990004977 A3 WO1990004977 A3 WO 1990004977A3 US 8904766 W US8904766 W US 8904766W WO 9004977 A3 WO9004977 A3 WO 9004977A3
Authority
WO
WIPO (PCT)
Prior art keywords
liquid nitrogen
recombinant dna
human alpha
alpha interferon
dna human
Prior art date
Application number
PCT/US1989/004766
Other languages
English (en)
Other versions
WO1990004977A2 (fr
Inventor
Kenneth A Smiles
Edwin A Peets
Daniel J Tanner
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Priority to KR1019900701395A priority Critical patent/KR900701309A/ko
Publication of WO1990004977A2 publication Critical patent/WO1990004977A2/fr
Publication of WO1990004977A3 publication Critical patent/WO1990004977A3/fr
Priority to DK079591A priority patent/DK79591A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

On traite des infections dites condylomata acuminata (condylome anogénital) chez de patients infectés au moyen d'une thérapie combinée, c'est à dire par application d'azote liquide et immédiatement après par administration d'interféron alpha humain trois fois par semaine pendant trois semaines. La composition pharmaceutique d'interféron utilisée dans ladite thérapie combinée contient un interféron alpha-2b humain d'ADN de recombinaison dans lequel 1,0 x 106 unités internationales sont administre par injection dans chaque lésion. L'azote liquide est l'agent cryochirurgical pris à titre d'exemple, et que l'on applique localement à chaque lésion par des moyens classiques. L'invention concerne également l'emploi d'interféron alpha humain pour la fabrication d'un médicament utilisé dans la thérapie combinée prise comme exemple.
PCT/US1989/004766 1988-11-01 1989-10-30 Traitement de condylomes genitaux a l'aide d'une combinaison d'azote liquide et d'interferon alpha humain d'adn de recombinaison WO1990004977A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1019900701395A KR900701309A (ko) 1988-11-01 1989-10-30 액체 질소 및 재조합 DNA사람 α인터페론을 혼용하여 생식기우종을 치료하는 방법
DK079591A DK79591A (da) 1988-11-01 1991-04-30 Behandling af genitale vorter med en kombination af flydende nitrogen og rekombinant dna human alfa-interferon

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/265,612 US4959210A (en) 1988-11-01 1988-11-01 Treatment of genital warts with a combination of liquid nitrogen and recombinant DNA human alpha interferon
US265,612 1988-11-01

Publications (2)

Publication Number Publication Date
WO1990004977A2 WO1990004977A2 (fr) 1990-05-17
WO1990004977A3 true WO1990004977A3 (fr) 1990-06-28

Family

ID=23011173

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1989/004766 WO1990004977A2 (fr) 1988-11-01 1989-10-30 Traitement de condylomes genitaux a l'aide d'une combinaison d'azote liquide et d'interferon alpha humain d'adn de recombinaison

Country Status (12)

Country Link
US (1) US4959210A (fr)
EP (2) EP0369632A1 (fr)
JP (1) JPH03503766A (fr)
KR (1) KR900701309A (fr)
AU (1) AU636312B2 (fr)
CA (1) CA2001884A1 (fr)
DK (1) DK79591A (fr)
IL (1) IL92161A0 (fr)
MY (1) MY106603A (fr)
PH (1) PH26680A (fr)
WO (1) WO1990004977A2 (fr)
ZA (1) ZA898234B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5028422A (en) * 1986-05-27 1991-07-02 Schering Corporation Treatment of basal cell carcinoma intralesionally with recombinant human alpha interferon
US5165921A (en) * 1989-01-23 1992-11-24 National Geno Sciences, Inc. Method for treating condyloma acuminatum with interferon
US6001826A (en) * 1989-12-21 1999-12-14 Anormed, Inc. Chemical compounds
PT99837A (pt) * 1990-12-21 1992-12-31 Schering Corp Processo para a preparacao de composicoes farmaceuticas contendo interferao alfa e metodo para administracao de interferao alfa por inalacao oral para tratar asma e doencas pulmonares proliferativas nao malignas
US6309662B1 (en) 1999-09-23 2001-10-30 Janet Buchanan Use of anti-inflammatory drugs for treatment of dermatological conditions
US7436227B2 (en) * 2003-05-02 2008-10-14 Silicon Laboratories Inc. Dual loop architecture useful for a programmable clock source and clock multiplier applications
KR20070007086A (ko) 2004-02-02 2007-01-12 암브룩스, 인코포레이티드 변형된 인간의 4 개의 나선형 다발 폴리펩티드 및 이의용도
US20110218241A1 (en) * 2010-03-06 2011-09-08 Cacao Bio-Technologies, Llc Antiviral epicatechins, epicatechin oligomers, or thiolated epicatechins from theobroma cacao for treatment of genital warts
AU2018246292A1 (en) 2017-03-31 2019-10-10 Accanis Biotech F&E Gmbh & Co Kg Prevention and treatment of non-melanoma skin cancer (NMSC)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4503035B1 (en) * 1978-11-24 1996-03-19 Hoffmann La Roche Protein purification process and product
US4286690A (en) * 1979-03-05 1981-09-01 Commercial Management Corporation Escape device
JPS59175416A (ja) * 1983-03-25 1984-10-04 Sunstar Inc 皮膚および粘膜の角化異常治療用外用剤
CA1321347C (fr) * 1986-11-10 1993-08-17 David C. Munch Composition d'interferon humain leucocytaire et traitement de la peau

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
H. HELWIG et al.: "Helwig Arzneimittel ein Handbuch fur Arzte und Apotheker", Vol. II, October 1988, 6th Edition, Wissenschaftliche Verlagsgesellschaft mbH, (Stuttgart, DE), pages 34-54 - 34-55 *

Also Published As

Publication number Publication date
DK79591A (da) 1991-06-14
DK79591D0 (da) 1991-04-30
US4959210A (en) 1990-09-25
ZA898234B (en) 1990-07-25
MY106603A (en) 1995-06-30
JPH03503766A (ja) 1991-08-22
CA2001884A1 (fr) 1990-05-01
EP0369632A1 (fr) 1990-05-23
WO1990004977A2 (fr) 1990-05-17
KR900701309A (ko) 1990-12-01
AU4524689A (en) 1990-05-28
EP0445145A1 (fr) 1991-09-11
PH26680A (en) 1992-09-15
AU636312B2 (en) 1993-04-29
IL92161A0 (en) 1990-07-12

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