WO1990002728A3 - Derives de 6-oxo-9-fluor-prostaglandine, leur procede de production et leur utilisation pharmaceutique - Google Patents
Derives de 6-oxo-9-fluor-prostaglandine, leur procede de production et leur utilisation pharmaceutique Download PDFInfo
- Publication number
- WO1990002728A3 WO1990002728A3 PCT/DE1989/000588 DE8900588W WO9002728A3 WO 1990002728 A3 WO1990002728 A3 WO 1990002728A3 DE 8900588 W DE8900588 W DE 8900588W WO 9002728 A3 WO9002728 A3 WO 9002728A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- group
- free
- hydrogen atom
- functionally modified
- fluor
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 2
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 2
- XAKBSHICSHRJCL-UHFFFAOYSA-N [CH2]C(=O)C1=CC=CC=C1 Chemical group [CH2]C(=O)C1=CC=CC=C1 XAKBSHICSHRJCL-UHFFFAOYSA-N 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000006376 (C3-C10) cycloalkyl group Chemical group 0.000 abstract 1
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19883831222 DE3831222A1 (de) | 1988-09-09 | 1988-09-09 | 6-oxo-9-fluor-prostaglandin-derivate verfahren zu ihrer herstellung und ihre pharmazeutische verwendung |
DEP3831222.0 | 1988-09-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1990002728A2 WO1990002728A2 (fr) | 1990-03-22 |
WO1990002728A3 true WO1990002728A3 (fr) | 1990-07-26 |
Family
ID=6362926
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE1989/000588 WO1990002728A2 (fr) | 1988-09-09 | 1989-09-10 | Derives de 6-oxo-9-fluor-prostaglandine, leur procede de production et leur utilisation pharmaceutique |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0434707A1 (fr) |
DE (1) | DE3831222A1 (fr) |
WO (1) | WO1990002728A2 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5545666A (en) * | 1992-10-20 | 1996-08-13 | Taisho Pharmaceutical Co., Ltd. | Prostaglandin derivatives |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0069696A2 (fr) * | 1981-07-03 | 1983-01-12 | Schering Aktiengesellschaft | Dérivés prostaglandines-9-fluorés, leur préparation et application comme médicament |
ZA881777B (en) * | 1987-03-13 | 1988-09-09 | Schering Aktiengesellschaft | 6-oxoprostaglandin-e derivatives.method for their manufacture and their use as pharmaceuticals |
-
1988
- 1988-09-09 DE DE19883831222 patent/DE3831222A1/de not_active Withdrawn
-
1989
- 1989-09-10 WO PCT/DE1989/000588 patent/WO1990002728A2/fr not_active Application Discontinuation
- 1989-09-10 EP EP19890909709 patent/EP0434707A1/fr not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0069696A2 (fr) * | 1981-07-03 | 1983-01-12 | Schering Aktiengesellschaft | Dérivés prostaglandines-9-fluorés, leur préparation et application comme médicament |
ZA881777B (en) * | 1987-03-13 | 1988-09-09 | Schering Aktiengesellschaft | 6-oxoprostaglandin-e derivatives.method for their manufacture and their use as pharmaceuticals |
Non-Patent Citations (1)
Title |
---|
Tele Systems, File Server, Databasis W.P.I.L. (Derwent), Nr. 88-271929 (39), siehe die Zusammenfassung & ZA 8801777 (Schering AG) 9. September 1988 & DE, A, 3708537 * |
Also Published As
Publication number | Publication date |
---|---|
DE3831222A1 (de) | 1990-03-22 |
EP0434707A1 (fr) | 1991-07-03 |
WO1990002728A2 (fr) | 1990-03-22 |
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