WO1988000696A3 - Chemosenseur et son utilisation - Google Patents

Chemosenseur et son utilisation Download PDF

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Publication number
WO1988000696A3
WO1988000696A3 PCT/EP1987/000379 EP8700379W WO8800696A3 WO 1988000696 A3 WO1988000696 A3 WO 1988000696A3 EP 8700379 W EP8700379 W EP 8700379W WO 8800696 A3 WO8800696 A3 WO 8800696A3
Authority
WO
WIPO (PCT)
Prior art keywords
selective
selective matrix
reaction
substance
measured
Prior art date
Application number
PCT/EP1987/000379
Other languages
German (de)
English (en)
Other versions
WO1988000696A2 (fr
Inventor
Ralph A Werner
Julio R Moran
Original Assignee
Prosumus Ag
Ralph A Werner
Julio R Moran
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prosumus Ag, Ralph A Werner, Julio R Moran filed Critical Prosumus Ag
Priority to AT87904530T priority Critical patent/ATE76505T1/de
Priority to DE8787904530T priority patent/DE3779288D1/de
Publication of WO1988000696A2 publication Critical patent/WO1988000696A2/fr
Publication of WO1988000696A3 publication Critical patent/WO1988000696A3/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G01N21/7743—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure the reagent-coated grating coupling light in or out of the waveguide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0385—Diffusing membrane; Semipermeable membrane
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1738—Optionally different kinds of measurements; Method being valid for different kinds of measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7779—Measurement method of reaction-produced change in sensor interferometric

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Pour mettre en oeuvre un procédé de détection amélioré avec un nouveau chémosenseur, celui-ci est muni d'un film conducteur d'ondes constitué d'une matrice sélective (11) sur un substrat (10) avec ou sans réseau de diffraction (17). Il est toujours possible d'amener un rayon notamment un rayon laser sur un détecteur, que celui-ci soit muni d'un réseau (17) de diffraction et d'une couche sélective supplémentaire (15) ou non. Il s'y produit alors un changement des propriétés physiques à la suite de réactions entre des réactifs sélectifs et la substance objet de la mesure dans la mtrice sélective sans l'aide d'agents marqueurs, changement qui peut provenir d'une addition moléculaire d'une transposition moléculaire ou de transformation moléculaire par réaction chimique. Après avoir obtenu l'interaction entre la matière sélective et le milieu contenant la substance, on mesure le changement des propriétés physiques.
PCT/EP1987/000379 1986-07-17 1987-07-14 Chemosenseur et son utilisation WO1988000696A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AT87904530T ATE76505T1 (de) 1986-07-17 1987-07-14 Chemosensor.
DE8787904530T DE3779288D1 (en) 1986-07-17 1987-07-14 Chemosensor.

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DEP3624120.2 1986-07-17
DE3624120 1986-07-17
DE3637379 1986-11-03
DEP3637379.6 1986-11-03

Publications (2)

Publication Number Publication Date
WO1988000696A2 WO1988000696A2 (fr) 1988-01-28
WO1988000696A3 true WO1988000696A3 (fr) 1988-04-07

Family

ID=25845646

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1987/000379 WO1988000696A2 (fr) 1986-07-17 1987-07-14 Chemosenseur et son utilisation

Country Status (3)

Country Link
EP (1) EP0275275B1 (fr)
DE (1) DE3779288D1 (fr)
WO (1) WO1988000696A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8807486D0 (en) * 1988-03-29 1988-05-05 Ares Serono Res & Dev Ltd Waveguide sensor
JPH05504195A (ja) * 1990-02-22 1993-07-01 ザ・ロイヤル・インステイチユーシヨン・フオー・ジ・アドバンスメント・オブ・ラーニング　（マクギル・ユニバーシテイ） 固相干渉イムノアッセイ系
DE4312403A1 (de) * 1993-04-16 1994-10-20 Jenoptik Jena Gmbh Verfahren und Anordnung zur Bestimmung einer zumindest annähernd kreisförmigen Berührungsfläche
US5413939A (en) * 1993-06-29 1995-05-09 First Medical, Inc. Solid-phase binding assay system for interferometrically measuring analytes bound to an active receptor
FR2734373B1 (fr) * 1995-05-19 1997-07-04 Gaz De France Coupleur optique a taux de derivation variable et utilisation en tant que capteur

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3905767A (en) * 1974-01-30 1975-09-16 Miles Lab Process for qualitative analysis or quantitation of antigens or antibodies
EP0120203A1 (fr) * 1983-03-23 1984-10-03 Cerberus Ag Dispositif pour la détection de polluants gazeux dans l'air au moyen d'un détecteur de gaz
DE3429562A1 (de) * 1983-08-12 1985-02-28 Hochiki K.K., Tokio/Tokyo Gassensor
EP0144713A2 (fr) * 1983-12-06 1985-06-19 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Installation pour la mesure optique de concentration de substances
US4558012A (en) * 1982-04-26 1985-12-10 Sagax Instrument Ab Method and member for detecting and/or measuring the concentration of a chemical substance
WO1986007149A1 (fr) * 1985-05-29 1986-12-04 Kurt Tiefenthaler Senseur optique pour etablir selectivement la presence de substances ainsi que la variation d'indice de refraction dans les substances objet de mesures
EP0234928A2 (fr) * 1986-02-27 1987-09-02 Eli Lilly And Company Dispositif à fibre optique

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60209149A (ja) * 1984-03-31 1985-10-21 Nippon Sheet Glass Co Ltd 水素感知器

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3905767A (en) * 1974-01-30 1975-09-16 Miles Lab Process for qualitative analysis or quantitation of antigens or antibodies
US4558012A (en) * 1982-04-26 1985-12-10 Sagax Instrument Ab Method and member for detecting and/or measuring the concentration of a chemical substance
EP0120203A1 (fr) * 1983-03-23 1984-10-03 Cerberus Ag Dispositif pour la détection de polluants gazeux dans l'air au moyen d'un détecteur de gaz
DE3429562A1 (de) * 1983-08-12 1985-02-28 Hochiki K.K., Tokio/Tokyo Gassensor
EP0144713A2 (fr) * 1983-12-06 1985-06-19 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Installation pour la mesure optique de concentration de substances
WO1986007149A1 (fr) * 1985-05-29 1986-12-04 Kurt Tiefenthaler Senseur optique pour etablir selectivement la presence de substances ainsi que la variation d'indice de refraction dans les substances objet de mesures
EP0234928A2 (fr) * 1986-02-27 1987-09-02 Eli Lilly And Company Dispositif à fibre optique

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Optics Letters, Band 9, Nr. 4, April 1984, Optical Society of America, (New York, US), K. TIEFENTHALER et al.: "Integrated Optical Switches and Gas Sensors", seiten 137-139 siehe seite 137; figuren 1-3 *
PATENT ABSTRACTS OF JAPAN, Band 10, Nr. 68 (P-437)(2125), 18. Marz 1986, & JP, A, 60209149 (Nihon Ita Glass K.K.) 21. Oktober 1985 *

Also Published As

Publication number Publication date
WO1988000696A2 (fr) 1988-01-28
EP0275275B1 (fr) 1992-05-20
EP0275275A1 (fr) 1988-07-27
DE3779288D1 (en) 1992-06-25

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