WO1987007609A1 - 1,1,2-triaryl-1-butene derivatives - Google Patents

1,1,2-triaryl-1-butene derivatives Download PDF

Info

Publication number
WO1987007609A1
WO1987007609A1 PCT/JP1987/000385 JP8700385W WO8707609A1 WO 1987007609 A1 WO1987007609 A1 WO 1987007609A1 JP 8700385 W JP8700385 W JP 8700385W WO 8707609 A1 WO8707609 A1 WO 8707609A1
Authority
WO
WIPO (PCT)
Prior art keywords
triaryl
lower alkyl
alkyl group
butene derivatives
group
Prior art date
Application number
PCT/JP1987/000385
Other languages
English (en)
French (fr)
Inventor
Tetsuji Asao
Setsuo Takeda
Yoshikazu Sugimoto
Toshiyuki Toko
Yuji Yamada
Kazuo Ogawa
Norio Unemi
Original Assignee
Taiho Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co., Ltd. filed Critical Taiho Pharmaceutical Co., Ltd.
Priority to DE8787903918T priority Critical patent/DE3770251D1/de
Publication of WO1987007609A1 publication Critical patent/WO1987007609A1/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PCT/JP1987/000385 1986-06-16 1987-06-12 1,1,2-triaryl-1-butene derivatives WO1987007609A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE8787903918T DE3770251D1 (de) 1986-06-16 1987-06-12 1,1,2-triaryl-1-buten-derivate.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP61/139897 1986-06-16
JP13989786 1986-06-16

Publications (1)

Publication Number Publication Date
WO1987007609A1 true WO1987007609A1 (en) 1987-12-17

Family

ID=15256159

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP1987/000385 WO1987007609A1 (en) 1986-06-16 1987-06-12 1,1,2-triaryl-1-butene derivatives

Country Status (7)

Country Link
US (1) US4897503A (ja)
EP (1) EP0272330B1 (ja)
JP (1) JPH0557277B1 (ja)
AU (1) AU611090B2 (ja)
CA (1) CA1289570C (ja)
ES (1) ES2007052A6 (ja)
WO (1) WO1987007609A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4897503A (en) * 1986-06-16 1990-01-30 Taiho Pharmaceutical 1,1,2-triaryl-1-alkene derivatives
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681835A (en) * 1994-04-25 1997-10-28 Glaxo Wellcome Inc. Non-steroidal ligands for the estrogen receptor
RU2214236C2 (ru) 1997-08-15 2003-10-20 Дьюк Юниверсити Способ профилактики или лечения эстрогензависимых заболеваний и расстройств
SI2989110T1 (sl) * 2013-04-24 2019-01-31 Smart Brain s.r.o. Derivati tamoksifena za zdravljenje neoplastičnih bolezni, predvsem z višjo stopnjo proteina HER2

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE637389A (ja) * 1962-09-13
GB1013907A (en) * 1962-09-13 1965-12-22 Ici Ltd Alkene derivatives
US3288806A (en) * 1964-03-23 1966-11-29 Parke Davis & Co Alpha-(aminoethoxyphenyl)-alpha-alkylstilbenes
GB1560274A (en) * 1977-02-28 1980-02-06 Ici Ltd Phenylbut 1-ene derivatives having antiostrogenicactivity
EP0002097B1 (en) * 1977-08-22 1981-08-05 Imperial Chemical Industries Plc Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them
GB2003855B (en) * 1977-08-22 1982-10-27 Ici Ltd Triphenylbut-1-ene derivatives
US4206234A (en) * 1977-08-22 1980-06-03 Imperial Chemical Industries Limited Triphenylbut-1-ene derivatives and pharmaceutical compositions and uses thereof
CA1289570C (en) * 1986-06-16 1991-09-24 Tetsuji Asao 1,1,2-triaryl-1-alkene derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP0272330A4 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4897503A (en) * 1986-06-16 1990-01-30 Taiho Pharmaceutical 1,1,2-triaryl-1-alkene derivatives
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia

Also Published As

Publication number Publication date
ES2007052A6 (es) 1989-06-01
EP0272330A4 (en) 1988-10-20
US4897503A (en) 1990-01-30
JPH0557277B1 (ja) 1993-08-23
AU611090B2 (en) 1991-06-06
CA1289570C (en) 1991-09-24
EP0272330B1 (en) 1991-05-22
EP0272330A1 (en) 1988-06-29
AU7519987A (en) 1988-01-11

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