WO1987007157A1 - Appareil de distribution de liquide et cartouche - Google Patents

Appareil de distribution de liquide et cartouche Download PDF

Info

Publication number
WO1987007157A1
WO1987007157A1 PCT/US1986/001172 US8601172W WO8707157A1 WO 1987007157 A1 WO1987007157 A1 WO 1987007157A1 US 8601172 W US8601172 W US 8601172W WO 8707157 A1 WO8707157 A1 WO 8707157A1
Authority
WO
WIPO (PCT)
Prior art keywords
cylinder
liquid
plunger
cartridge
biasing
Prior art date
Application number
PCT/US1986/001172
Other languages
English (en)
Inventor
David M. Maurice
Original Assignee
Alpha Group, Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpha Group, Incorporated filed Critical Alpha Group, Incorporated
Priority to EP19860903926 priority Critical patent/EP0272256A4/fr
Priority to PCT/US1986/001172 priority patent/WO1987007157A1/fr
Publication of WO1987007157A1 publication Critical patent/WO1987007157A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein

Definitions

  • This invention relates to an apparatus for the repetitive dispensing of a predetermined quantity of a liquid. It also relates to a cartridge containing the liquid to be dispensed in the apparatus. Most especially, it relates to such an apparatus and cartridge which are especially adapted for dispensing eyedrops in an improved manner.
  • an object of this invention to provide an apparatus for the repetitive dispensing of a predetermined quantity of a liquid by the application of pressure which is of sufficiently simplified construction that the apparatus may be provided in disposable form.
  • An apparatus in accordance with this invention includes a cylinder having a first end and a second closed end.
  • the first end of the cylinder has a restricted opening through which the liquid may pass in response to pressure applied to the liquid.
  • At least one of the first and second ends is movable within the cylinder toward the other end to change volume of a space defined by the cylinder and containing the liquid.
  • a biasing member engages the second end for moving the ends in steps toward one another.
  • An actuating member engages the biasing member by means of opposed surfaces on each member. One of the opposing surfaces constitutes a ramped cam having at least one step.
  • the other of the opposing surfaces has at least one projection engaging the ramped cam opposing surface.
  • a means such as a spring, biases the opposed surfaces toward each other.
  • the biasing and actuating members are rotatable with respect to each other. Rotation of the biasing and actuating members with respect to each other moves the projection on the ramped cam opposing surface. Movement of the projection over the step advances the ends toward one another a distance corresponding to the step.
  • a cartridge in accordance with the invention for insertion in an apparatus in accordance with the invention is formed from a cylinder having a first end through which the liquid is dispensed and a second, closed end.
  • an apparatus for the repetitive dispensing of a predetermined quantity of a liquid has a housing including a cylinder having a first end through which the liquid is dispensed through application of pressure.
  • An opening in the housing is configured to receive a neck of a bottle.
  • There is a reservoir in the housing connected to the opening and to the cylinder.
  • a means in the housing applies pressure to liquid in the cylinder.
  • a tube extends from the opening and has a length such that a first end extends above the liquid in the bottle when the bottle is in the opening.
  • the tube has a second end connected to ambient pressure.
  • the simplified construction of the apparatus of this invention allows the apparatus to be provided as a disposable unit containing eyedrops to other liquid to be repetitively dispensed in predetermined quantities by the application of pressure.
  • the liquid may be provided in the cartridge of this invention, for easy insertion in the apparatus.
  • the form of the invention for use with a bottle provides improved pressure relief for the bottle.
  • Figure 1 is a lateral cross section view of an apparatus in accordance with the invention.
  • Figure 2 is a cross section view, taken along the line 2-2 in Figure 1.
  • Figure 3 is a cross section view, taken along the line 3-3 in Figure 1.
  • Figure 4 is an enlarged view of a portion of the apparatus shown in figure 1.
  • Figure 5 is a cross section view of a portion of another apparatus in accordance with the invention.
  • Figure 6 is another cross section view of another portion of the apparatus in Figure 5.
  • Figure 7 is another cross section view of a portion of another apparatus in accordance with the invention.
  • Figure 8 is another cross section view of a portion of yet another apparatus in accordance with the invention.
  • Figure 9 is a cross section view of still another apparatus in accordance with the invention.
  • the apparatus 10 includes a cylinder 14, containing the eyedrops 12.
  • the cylinder 14 has a first end 16 with a nozzle 18 through which the eyedrops 12 are projected.
  • a plunger 20 extends into the cylinder 14 from a second end 22.
  • Rod 23 extends from plunger 20 from the second end 22 of the cylinder 14.
  • the cylinder 14 is implemented as a sleeve, which is friction fit into threaded member 24.
  • Actuating member 26 is circumferentially disposed around the threaded member 24 and threaded thereto.
  • a biasing member 28 is also circumferentially disposed around the threaded member 24, between the threaded member 24 and the actuating member 26. Biasing member 28 engages the rod 23. Surfaces 30 and 32, respectively on the actuating member 26 and the biasing member 28, are in opposing relationship (see also Figure 4) .
  • Threaded member 24 has a slot 34 ( Figures 2 and 3) extending along its length.
  • Biasing member 28 has a spline 36 ( Figure 3) , which fits into the slot 34 to prevent rotation of the biasing member 28 with respect to the threaded member 24.
  • Threaded member 24 forms part of housing 38, which extends around the apparatus, with the exception of handle 40.
  • a compressed spring 42 is connected to handle 40 and extends between the handle 40 of actuating member 26 and the biasing member 28.
  • FIG. 3 and 4 Details of a ramped cam mechanism formed by surface 32 on biasing member 28 and projection 44, extending from surface 30 on actuating member 26 are shown in Figures 3 and 4.
  • steps 46 There is a pair of steps 46 on the surface 32.
  • the surface 32 is inclined, leading up to each step 46.
  • Spring 42 ( Figure 1) biases the surfaces 30 and 32 toward one another.
  • Projection 44 rides up the inclined surface 32 to each step 46 as knob 40 is turned. Turning the knob 40 also advances the actuating member 26 on the threaded member 24 toward first end 16 of the cylinder 14.
  • biasing member 28 is also permitted to move in stepwise increments corresponding to the height of step 46 toward first end 16 of the cylinder 14.
  • Biasing member 28 then pushes against rod 23, to push the plunger 20 toward first end 16 of the cylinder 14 a corresponding amount.
  • the resulting pressure on eyedrops 12 discharges a predetermined amount of the eyedrops 12 through the nozzle 18 in the form of a jet.
  • the stepwise movement of plunger is repeated, until the plunger 20 has reached end 16 of the cylinder 14.
  • the pitch of the threads on threaded member 24 and actuating member 26 should be dimensioned so that leftward motion of the actuation member 26 for each half revolution on threaded member 24 corresponds to the height of step 46.
  • the eyedrops 12 should completely fill the space between end 16 and plunger 20 at all times. Trapped air in this space would produce unpredictable operation due to compression of the air. Because the ramped cam mechanism is not visible in operation of the dispenser, the user does not know when the jet of eyedrops will be discharged, and so does not blink in anticipation.
  • Figures 5 and 6 show portions of another embodiment of an apparatus in accordance with the invention, in which the cylinder 14 is replaced with an insertable cartridge 50, which is slidably positioned in bore 52 of a threaded member 54, corresponding to the threaded member 24 in Figure 1.
  • Bore 52 has a wall 56 through which a hollow needle 58 extends.
  • Cartridge 50 has a cylinder 60, formed from glass or rigid plastic.
  • End plug 62 formed from a resilient, puncturable plastic is inserted in end 64 of the cylinder 60.
  • a plunger 66 and rod 68 are inserted in the other end 70 of the cylinder 60, with the eyedrops 72 between the plug 62 and the plunger 66.
  • Actuating member 74 and biasing member 76 respectively correspond to the actuating member 26 and biasing member 28 in Figure 1.
  • the actuating member 74 and biasing member 76 each have removable caps 78 and 80 to allow insertion and removal of new and spent cartridges 50.
  • the construction and operation of the Figures 5 and 6 embodiment of the invention is the same as the Figures 1 through 4 embodiment.
  • FIG 7 shows another form of an insertable cartridge 100 for use in a dispensing apparatus in accordance with the invention.
  • the cartridge 100 has a cylinder 102, formed from glass or a rigid plastic, a plug 104 near one end of the cylinder 102, and a plunger 106 extending into the cylinder 102 from the other direction. Liquid 108 to be dispensed fills the space between plug 104 and plunger 106.
  • a second plug 110 is mounted in the tube 102 on the other side of plug 104 from the liquid 108.
  • Plug 110 supports an axially disposed, hollow needle 112, positioned to puncture the resilient plug 104 in a manner similarly to 1 that of the needle 58 in Figure 5. Needle 112 extends
  • Figure 8 shows another form of a cartridge 120 and g puncturing assembly 122 for use with the cartridge 120.
  • the cartridge 120 has a cylinder 124, closed at one end and 0 having a plug 126 near the other end, similar to the plugs 62 and 104 in Figures 5 and 7.
  • the puncturing assembly 122 2 has a cylindrical mandrel 128 having an axially disposed 3 puncturing needle 130 positioned to puncture resilient end 4 plug 126 of the cartridge 120.
  • Liquid 132 fills the space 5 defined by cylinder 124 and plug 126.
  • Cylinder 124 is 6 dimensioned so that mandrel 128 enters the cylinder 124 as 7 cartridge 120 is pushed to the left during operation of the 8 apparatus.
  • FIG. 9 shows another dispensing apparatus 140 in 7 accordance with the invention.
  • the apparatus 140 has a 8 generally cylindrically shaped body 142 having a threaded 9 opening 144 into which a conventional eyedrop bottle 146 is 0 inserted as shown.
  • the body 142 contains a reservoir 148, 1 into which eyedrops 150 flow from the bottle 146.
  • Conduit 2 152 connects the reservoir 148 to cylinder 154.
  • the cylinder 154 has a restricted opening 156 at end 158 and a plunger 160, extending into the cylinder 154 from end 162.
  • a ramped cam 164 is disposed circumferentially around end 166 of the plunger 160, extending from the end 162 of cylinder 154.
  • Ramped cam 164 has a step 168, which defines a path of travel of the plunger 160 within cylinder 154.
  • Projection 170 on the plunger 160 rides on the ramped cam 164 and drops over step 168 to define the stroke of the plunger 160 within cylinder 154.
  • Knob 172 is turned to move the projection 170 along ramped cam 164.
  • Spring 174 connects plunger 160 and knob 172, and is compressed to urge the plunger 160 toward end 158 of the cylinder 154. Rectangular portion 172a of knob 172 extends into portion 160a of plunger 160 so that rotary motion of knob 172 is transmitted to plunger 160.
  • a pressure equalization tube 180 extends into the bottle 146 to allow entry of additional air as the eyedrops 150 are discharged. As shown, the pressure equalization tube 180 has a hooked portion 181 and has its end 182 positioned at the center of gravity 183 of the volume enclosed by bottle 146 and reservoir 148.
  • Reservoir 148 within housing 142 is of sufficient size so that when a full bottle 146 of eyedrops 150 is inserted in the housing 142 and inverted, the level of eyedrops 150 is below opening 182. Under these circumstances, the opening 182 will be above the eyedrops 150, whatever the orientation of the dispenser.
  • the hooked portion 181 in tube 180 serves to reduce leakage of eyedrops 150 through the pressure equalization tube 180 either through splashing or drainage over the tube 180.
  • Cylindrical lip 190 on the body 142 is used for positioning the dispensing apparatus 140 in front of the user's eye.
  • the apparatus of the invention is of simplified construction, it may be provided in disposable form, already charged with eyedrops 12 or other liquid to be repetitively dispensed in a predetermined quantity.
  • a disposable cartridge containing eyedrops 72 or other liquid to be repetitively dispensed in a predetermined quantity can be inserted into the apparatus.
  • the rotatable, stepped cam mechanism for actuating the apparatus allows the provision of such an apparatus of simplified construction.
  • the pressure relief structure of the invention allows improved operation of a dispensing apparatus of the invention used with a conventional bottle of liquid.

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

Un appareil (10) pour la distribution goutte à goutte d'une quantité prédéterminée de liquide (12) comporte un cylindre (14) ayant une ouverture restreinte (18) au niveau d'une première extrémité (16). Un plongeur (20) fixé à une tige (23) s'étend dans le cylindre (14) à partir de l'extrémité (22). Un élément de sollicitation (28) présente une surface de came inclinée (32) présentant une paire de paliers (46), un élément d'actionnement (26) présentant une surface opposée ayant une partie en saillie (44) qui chevauche la surface de came inclinée (32) et glisse pour retomber sur le palier inférieur (46) lors de la rotation de l'élément d'actionnement (26). Ladite rotation de l'élément d'actionnement (26) permet également de faire avancer l'élément d'actionnement (26) sur l'élément fileté (24). Un ressort (42) agit de façon à rapprocher les surfaces (30 et 32). Au fur et à mesure que la partie en saillie (44) glisse sur chaque palier (46), le plongeur (20) se déplace de façon incrémentielle en direction de l'extrémité (16) du cylindre (14), afin de libérer les gouttes du liquide (12) à travers l'ouverture (18). Une cartouche jetable (50) peut remplacer le cylindre (14).
PCT/US1986/001172 1986-05-30 1986-05-30 Appareil de distribution de liquide et cartouche WO1987007157A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP19860903926 EP0272256A4 (fr) 1986-05-30 1986-05-30 Appareil de distribution de liquide et cartouche.
PCT/US1986/001172 WO1987007157A1 (fr) 1986-05-30 1986-05-30 Appareil de distribution de liquide et cartouche

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1986/001172 WO1987007157A1 (fr) 1986-05-30 1986-05-30 Appareil de distribution de liquide et cartouche

Publications (1)

Publication Number Publication Date
WO1987007157A1 true WO1987007157A1 (fr) 1987-12-03

Family

ID=22195525

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1986/001172 WO1987007157A1 (fr) 1986-05-30 1986-05-30 Appareil de distribution de liquide et cartouche

Country Status (2)

Country Link
EP (1) EP0272256A4 (fr)
WO (1) WO1987007157A1 (fr)

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE620218A (fr) *
US2345302A (en) * 1942-05-08 1944-03-28 Arthur E Smith Anesthetizing syringe
US2733848A (en) * 1956-02-07 bos houwers
US3162217A (en) * 1962-09-25 1964-12-22 Fisher Scientific Co Hypodermic syringe
US3353537A (en) * 1965-08-11 1967-11-21 George W Knox Automatic multi-dosage inoculating instrument
US3535068A (en) * 1968-07-29 1970-10-20 Lincoln Lab Inc Disposable injector and holder therefor
US4013370A (en) * 1975-12-01 1977-03-22 Antoine Gingras Fountain tooth-brush
US4019654A (en) * 1976-02-25 1977-04-26 Voplex Corporation Manual cartridge dispenser
US4444560A (en) * 1981-11-12 1984-04-24 John Jacklich Dental instrument-PDL syringe
US4498904A (en) * 1981-02-12 1985-02-12 Turner Robert C Dose metering plunger devices for use with syringes
US4522319A (en) * 1983-06-16 1985-06-11 The Coca-Cola Company Retention device for flow rate control tube within a discharge container
US4531944A (en) * 1983-04-28 1985-07-30 Bechtle Samuel J Eye drop application aid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3855931A (en) * 1967-09-01 1974-12-24 Trw Inc Salvo ammunition for multiple bore open chamber gun

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE620218A (fr) *
US2733848A (en) * 1956-02-07 bos houwers
US2345302A (en) * 1942-05-08 1944-03-28 Arthur E Smith Anesthetizing syringe
US3162217A (en) * 1962-09-25 1964-12-22 Fisher Scientific Co Hypodermic syringe
US3353537A (en) * 1965-08-11 1967-11-21 George W Knox Automatic multi-dosage inoculating instrument
US3535068A (en) * 1968-07-29 1970-10-20 Lincoln Lab Inc Disposable injector and holder therefor
US4013370A (en) * 1975-12-01 1977-03-22 Antoine Gingras Fountain tooth-brush
US4019654A (en) * 1976-02-25 1977-04-26 Voplex Corporation Manual cartridge dispenser
US4498904A (en) * 1981-02-12 1985-02-12 Turner Robert C Dose metering plunger devices for use with syringes
US4444560A (en) * 1981-11-12 1984-04-24 John Jacklich Dental instrument-PDL syringe
US4531944A (en) * 1983-04-28 1985-07-30 Bechtle Samuel J Eye drop application aid
US4522319A (en) * 1983-06-16 1985-06-11 The Coca-Cola Company Retention device for flow rate control tube within a discharge container

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP0272256A4 *

Also Published As

Publication number Publication date
EP0272256A4 (fr) 1989-07-26
EP0272256A1 (fr) 1988-06-29

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