WO1987005300A3 - Conservation de proteines - Google Patents
Conservation de proteines Download PDFInfo
- Publication number
- WO1987005300A3 WO1987005300A3 PCT/GB1987/000143 GB8700143W WO8705300A3 WO 1987005300 A3 WO1987005300 A3 WO 1987005300A3 GB 8700143 W GB8700143 W GB 8700143W WO 8705300 A3 WO8705300 A3 WO 8705300A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- protein preservation
- preservation
- protein
- water
- dependant
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868604983A GB8604983D0 (en) | 1986-02-28 | 1986-02-28 | Protein preservation |
GB8604983 | 1986-02-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1987005300A2 WO1987005300A2 (fr) | 1987-09-11 |
WO1987005300A3 true WO1987005300A3 (fr) | 1987-10-22 |
Family
ID=10593832
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1987/000143 WO1987005300A2 (fr) | 1986-02-28 | 1987-02-27 | Conservation de proteines |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0259425A1 (fr) |
JP (1) | JPS63502592A (fr) |
GB (1) | GB8604983D0 (fr) |
WO (1) | WO1987005300A2 (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8877162B2 (en) | 2000-05-10 | 2014-11-04 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery |
US9421166B2 (en) | 2001-12-19 | 2016-08-23 | Novartis Ag | Pulmonary delivery of aminoglycoside |
US9554993B2 (en) | 1997-09-29 | 2017-01-31 | Novartis Ag | Pulmonary delivery particles comprising an active agent |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8715238D0 (en) * | 1987-06-29 | 1987-08-05 | Quadrant Bioresources Ltd | Food process |
GB8801338D0 (en) * | 1988-01-21 | 1988-02-17 | Quadrant Bioresources Ltd | Preservation of viruses |
US5958670A (en) * | 1988-05-18 | 1999-09-28 | Cobe Laboratories, Inc. | Method of freezing cells and cell-like materials |
US5045446A (en) * | 1988-08-26 | 1991-09-03 | Cryopharm Corporation | Lyophilization of cells |
WO1990003795A1 (fr) * | 1988-10-05 | 1990-04-19 | Vestar, Inc. | Procede de fabrication de liposomes a stabilite amelioree pendant le sechage |
US5059518A (en) * | 1988-10-20 | 1991-10-22 | Coulter Corporation | Stabilized lyophilized mammalian cells and method of making same |
US5192663A (en) * | 1988-11-04 | 1993-03-09 | Immucor, Inc. | Article having an organic dye and a monolayer of dried mammalian cells and a method for utilizing the article |
US5030560A (en) * | 1988-11-04 | 1991-07-09 | Immucor, Inc. | Method for drying mammalian cells for use in solid phase immunoassays and articles incorporating same |
GB8903593D0 (en) | 1989-02-16 | 1989-04-05 | Pafra Ltd | Storage of materials |
USRE39497E1 (en) | 1989-02-16 | 2007-02-27 | Nektar Therapeutics | Storage of materials |
FR2645741B1 (fr) * | 1989-03-20 | 1995-06-23 | Dior Christian Parfums | Procede pour fixer un produit sur la membrane d'un keratinocyte au moyen d'une liaison ligand-recepteur, procede de preparation d'un tel produit, produit obtenu, composition cosmetique ou pharmaceutique le contenant et son procede de preparation |
ZA902663B (en) * | 1989-04-07 | 1991-12-24 | Syntex Inc | Interleukin-1 formulation |
IE64738B1 (en) * | 1990-03-20 | 1995-09-06 | Akzo Nv | Stabilized gonadotropin containing preparations |
US5270057A (en) * | 1990-03-20 | 1993-12-14 | Akzo N.V. | Stabilized gonadotropin containing preparations |
US5384132A (en) * | 1990-03-20 | 1995-01-24 | Akzo N.V. | Stabilized gonadotropin containing preparations |
GB9010742D0 (en) * | 1990-05-14 | 1990-07-04 | Quadrant Bioresources Ltd | Stabilization of biological macromolecular substances |
JPH05505680A (ja) * | 1991-01-11 | 1993-08-19 | コーブ ラボラトリーズ インコーポレイテッド | 乾燥または凍結乾燥した細胞または細胞―様物質を使用する循環抗体の型を検定する方法 |
AU659645B2 (en) | 1991-06-26 | 1995-05-25 | Inhale Therapeutic Systems | Storage of materials |
EP0624190A4 (fr) * | 1992-01-21 | 1995-04-19 | Cryopharm Corp | Procede de congelation de cellules et de matieres analogues a des cellules. |
JP3698721B2 (ja) * | 1993-02-23 | 2005-09-21 | ジェネンテク・インコーポレイテッド | 有機溶媒を用いて処理したポリペプチドの賦形剤安定化 |
EP0615747B1 (fr) | 1993-03-18 | 1999-09-29 | Terumo Kabushiki Kaisha | Liposome encapsulant de l'hémoglobine et procédé pour sa préparation |
US5674528A (en) * | 1994-06-15 | 1997-10-07 | Terumo Kabushiki Kaisha | Hemoglobin-encapsulated liposome |
US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
US6586006B2 (en) | 1994-08-04 | 2003-07-01 | Elan Drug Delivery Limited | Solid delivery systems for controlled release of molecules incorporated therein and methods of making same |
US6309671B1 (en) | 1995-04-14 | 2001-10-30 | Inhale Therapeutic Systems | Stable glassy state powder formulations |
GB9508691D0 (en) * | 1995-04-28 | 1995-06-14 | Pafra Ltd | Stable compositions |
PT831790E (pt) * | 1995-06-07 | 2003-07-31 | Elan Drug Delivery Ltd | Metodos para a incorporacao de modo estavel de substancias no interior de matrizes secas de vidro expandido e composicoes atraves deles obtidas |
US6632648B1 (en) | 1996-05-14 | 2003-10-14 | Elan Drug Delivery Limited | Methods of terminal sterilization of fibrinogen |
US6468782B1 (en) | 1996-12-05 | 2002-10-22 | Quadrant Healthcare (Uk) Limited | Methods of preserving prokaryotic cells and compositions obtained thereby |
ATE230923T1 (de) * | 1997-02-07 | 2003-02-15 | Elan Drug Delivery Ltd | Verfahren und zusammensetzungen zur herstellung getrockneter, lagerungsstabiler blutplättchen |
AU2001234978A1 (en) | 2000-02-10 | 2001-08-20 | The Regents Of The University Of California | Therapeutic platelets and methods |
US6770478B2 (en) | 2000-02-10 | 2004-08-03 | The Regents Of The University Of California | Erythrocytic cells and method for preserving cells |
BR0315767A (pt) * | 2002-11-01 | 2005-09-06 | Glaxosmithkline Biolog Sa | Composição imunogência, método para fabricar uma vacina, kit, vacina, recipiente com uma superfìcie interna repelente à água, e, método para preservar uma composição que compreende ipv e um agente estabilizador |
ES2502691B1 (es) * | 2013-09-25 | 2015-07-07 | Sani-Red, S.L. | Método de conservación y estabilización de proteínas, aplicable para desarrollos industriales de formulaciones de productos sanitarios, farmacéuticos y cosméticos |
WO2016209907A1 (fr) | 2015-06-25 | 2016-12-29 | The Regents Of The University Of California | Films de support stables pour microscopie électronique |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1855591A (en) * | 1926-02-03 | 1932-04-26 | Wallerstein Co Inc | Invertase preparation and method of making the same |
FR2532178A1 (fr) * | 1982-08-31 | 1984-03-02 | Asahi Chemical Ind | Procede pour stabiliser le facteur de necrose tumorale et solution aqueuse ou poudre stables contenant ce facteur |
EP0111216A2 (fr) * | 1980-03-31 | 1984-06-20 | Takeda Chemical Industries, Ltd. | Méthode pour essai immunoenzymatique, conjugué peptide-enzyme, son lyophilisat, anticorps et trousse de réactifs |
WO1986001103A1 (fr) * | 1984-08-08 | 1986-02-27 | The Liposome Company, Inc. | Liposomes deshydrates |
WO1986003938A1 (fr) * | 1985-01-11 | 1986-07-17 | The Regents Of The University Of California | Procede de conservation de liposomes |
WO1987000196A1 (fr) * | 1985-07-09 | 1987-01-15 | Quadrant Bioresources Limited | Protection des proteines et similaires |
-
1986
- 1986-02-28 GB GB868604983A patent/GB8604983D0/en active Pending
-
1987
- 1987-02-27 JP JP50150987A patent/JPS63502592A/ja active Pending
- 1987-02-27 EP EP19870901561 patent/EP0259425A1/fr not_active Withdrawn
- 1987-02-27 WO PCT/GB1987/000143 patent/WO1987005300A2/fr not_active Application Discontinuation
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1855591A (en) * | 1926-02-03 | 1932-04-26 | Wallerstein Co Inc | Invertase preparation and method of making the same |
EP0111216A2 (fr) * | 1980-03-31 | 1984-06-20 | Takeda Chemical Industries, Ltd. | Méthode pour essai immunoenzymatique, conjugué peptide-enzyme, son lyophilisat, anticorps et trousse de réactifs |
FR2532178A1 (fr) * | 1982-08-31 | 1984-03-02 | Asahi Chemical Ind | Procede pour stabiliser le facteur de necrose tumorale et solution aqueuse ou poudre stables contenant ce facteur |
WO1986001103A1 (fr) * | 1984-08-08 | 1986-02-27 | The Liposome Company, Inc. | Liposomes deshydrates |
WO1986003938A1 (fr) * | 1985-01-11 | 1986-07-17 | The Regents Of The University Of California | Procede de conservation de liposomes |
WO1987000196A1 (fr) * | 1985-07-09 | 1987-01-15 | Quadrant Bioresources Limited | Protection des proteines et similaires |
Non-Patent Citations (6)
Title |
---|
Archives of Biochemistry and Biophysics", Volume 242, No. 1, October 1985, Academic Press, Inc. L.M. CROWE et al.: "Preservation of Freeze-Dried Liposomes by Trehalose", pages 240-247, see the whole document * |
Biochemistry, Volume 24, 1985, American Chemical Society, (Washington, US), J. SZEBENI et al.: "Encapsulation of Hemoglobin in Phospholipid Liposomes: Characterization and Stability", pages 2827-2832, see pages 2827-2828 cited in the application * |
CHEMICAL ABSTRACTS, Volume 103, No. 12, 23 September 1985, (Columbus, Ohio, US) T.D. MADDEN et al.: "Protection of Large Unilamellar Vesicles by Trehalose During Dehydration: Retention of Vesicle Contents", see page 316, Abstract 92759a, & Biochim. Biophys, Acta 198k, 817(1), 67-74 cited in the application * |
CHEMICAL ABSTRACTS, Volume 85, No. 3, 19 July 1976, (Columbus, Ohio, US), P. LABRUDE et al.: "Lyophilization of Hemoglobin Solutions. Study of Protector Compounds Capable of Preventing the Formation of Methemoglobin", see page 415, Abstract 18011u, & J. Pharm. Belg. 1976, 31(2), 191-8 * |
Science, Volume 223, No. 4637, 17 February 1984, American Association for the Advancement of Science, (Washington, US), J.H. CROWE et al.: "Preservation of Membranes in Anhydrobiotic Organisms: the role of Trehalose", pages 701-703, see the whole document cited in the application * |
The Proceedings of Biotech '84 Europe, Volume 1, American Chemical Society "World Biotech Report 1984", pages 379-390, see pages 382-385 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9554993B2 (en) | 1997-09-29 | 2017-01-31 | Novartis Ag | Pulmonary delivery particles comprising an active agent |
US8877162B2 (en) | 2000-05-10 | 2014-11-04 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery |
US9439862B2 (en) | 2000-05-10 | 2016-09-13 | Novartis Ag | Phospholipid-based powders for drug delivery |
US9421166B2 (en) | 2001-12-19 | 2016-08-23 | Novartis Ag | Pulmonary delivery of aminoglycoside |
Also Published As
Publication number | Publication date |
---|---|
EP0259425A1 (fr) | 1988-03-16 |
JPS63502592A (ja) | 1988-09-29 |
GB8604983D0 (en) | 1986-04-09 |
WO1987005300A2 (fr) | 1987-09-11 |
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