WO1983000932A1 - Systeme de stockage et de distribution d'un agent de reaction - Google Patents

Systeme de stockage et de distribution d'un agent de reaction Download PDF

Info

Publication number
WO1983000932A1
WO1983000932A1 PCT/US1982/001194 US8201194W WO8300932A1 WO 1983000932 A1 WO1983000932 A1 WO 1983000932A1 US 8201194 W US8201194 W US 8201194W WO 8300932 A1 WO8300932 A1 WO 8300932A1
Authority
WO
WIPO (PCT)
Prior art keywords
container
hollow needle
interior
needle
supporting
Prior art date
Application number
PCT/US1982/001194
Other languages
English (en)
Inventor
Inc. Beckman Instruments
Arthur Milton Harris
Original Assignee
Beckman Instruments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Instruments Inc filed Critical Beckman Instruments Inc
Publication of WO1983000932A1 publication Critical patent/WO1983000932A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67D—DISPENSING, DELIVERING OR TRANSFERRING LIQUIDS, NOT OTHERWISE PROVIDED FOR
    • B67D3/00—Apparatus or devices for controlling flow of liquids under gravity from storage containers for dispensing purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/06—Test-tube stands; Test-tube holders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers

Definitions

  • the invention relates to the field of contain- ing apparatus. More particularly, the invention relates to a container system which includes a means for dispens ⁇ ing a substance- from the containers.
  • the invention includes at least one container which is secured to a rack wherein, upon securing the container to the rack, a seal on the container is pierced to allow the liquid within the container to be drained therefrom.
  • the invention is an apparatus for supplying one or more substances "to an analytical instrument. It in ⁇ cludes at least one container defining an interior of predetermined volume with a neck portion having an open ⁇ ing through the container communicating with the in- terior. A sealing means is insertable into the mouth. A supporting means onto which the container is secured includes a means for piercing the sealing means when the container is secured to the supporting means.
  • the supporting means includes a rack having receptacles to engage and secure the containers by engag ⁇ ing with a neck portion on the containers.
  • the recepta ⁇ cles include a hollow needle to pierce the septum which seals the opening in the neck portion of the container.
  • the hollow needle extends through the septum such that an inlet in the needle allows the reagent or other substance in the container to flow from the container through the needle and into an analytical instrument.
  • FIG. 1 is a partially sectioned view of the containers and the supporting rack
  • Fig. 2 is a sectional view of the container secured to the rack;
  • Fig. 3 is a view of the containers in a separ- ate storage rack; and Fig. 4 shows a container with a collapsible liner therein.
  • a plurality of containers 11, 12, and 13 each have a neck portion 14 defining a mouth 15 into which a septum 16 is inserted.
  • Neck por ⁇ tions 14 include threads 17 on the outside thereof.
  • Containers 11, 12, and 13 also include a frangible vent- tab 18.
  • Containers 11, 12, and 13 each define an in- terior of predetermined volume.
  • a supporting rack 19 includes container caps 21, 22, and 23, respectively, sized to fit containers 11, 12, and 13. Caps 21, 22, and 23 are attached to supporting rack 19.
  • Caps 21, 22, and 23 include threaded portions on the interior of the caps • for engagement with threaded neck portions 14 on contain ⁇ ers 11, 12, and 13.
  • Caps 21, 22, and 23 also include a hollow needle 24 preferably at the center of each cap.
  • a conduit 25 is connected to hollow needle 24.
  • FIG. 2 the attachment of a con- tainer to supporting rack 19 is shown.
  • this attachment will be described with ref ⁇ erence to container 11 , but it should be expressly under ⁇ stood that containers 12 and 13 are attached in a like manner.
  • Neck portion 14 of container 11 is threadably engaged with cap 21 , itself attached to supporting rack 19.
  • Septum 16 seals a liquid or other substance within the interior of container 11.
  • Hollow needle 24 pene ⁇ trates septum 16 and extends into the interior of con ⁇ tainer 11 such that an inlet 26 in hollow needle 24 com- unicates with the predetermined volume in container 11 allowing the liquid to flow therethrough.
  • Conduit 25 is attached to hollow needle 24.
  • containers 11, 12, and 13 may be placed in a separate storage rack 27 to allow storage of the reagents apart from the analytical instru ⁇ ment.
  • Containers 11, 12, and 13 include holes 28 left by the removal of the frangible vent tab 18 (Fig. 1).
  • a container 29 including a collapsible liner 31 in the interior prede ⁇ termined volume of container 29.
  • the threaded neck portion 14 may be attached to a supporting rack 19.
  • Septum 16 is configured as described above.
  • containers 11, 12, and 13 define predetermined volumes into which a reagent or other substance is placed.
  • Septum 16 fitting in mouth 15 of neck portions 14, provides a liquid and air ⁇ tight seal such that the reagent or other substance en ⁇ closed in containers 11, 12, and 13 is prevented from escaping.
  • Septums 16 are made of an elastomeric material such as silicone rubber such that, when containers 11, 12, and 13 are screwed into caps 21, 22, and 23, respec ⁇ tively, needles 24 pierce septum 16 and extend into the interior defined by the containers. This is more clearly shown in Fig. 2 where container 11 is shown in place as screwed into cap 21.
  • Reagent is conducted from container 11 to a reaction site (not shown) through hollow needle 24 and conduit 25.
  • frangible valve 18 is opened, such as by breaking the tab, so as to permit uniform flow of reagent.
  • the containers shown in Fig. 1 may be removed from rack 19 without leakage of the contents of contain- ers 11, 12 or 13. That is, if, for example, at the end of a day all the reagents are not used from containers 11, 12, or 13, then the containers may be removed to be stored in a refrigerated environment or other suitable location. Upon unscrewing containers 11, 12, and 13, needle 24 will be pulled back through septum 16. Because of the elastomeric nature of septum 16, however, the elastomeric material will fill the space formally occu ⁇ file by the needle and thus the hole punched by the nee- die 24 will be effectively sealed.
  • the container illustrated in Figs. 1 and 2 once the frangible vent is opened a hole is formed in the container bottom.
  • the container may be placed in a suitable holding means for storage such as storage rack 27 to keep the bottles turned neck down as shown in Fig. 3.
  • This rack may then be placed into the desired storage loca ⁇ tion.
  • This rack is similar to rack 19 except that no needles are included to penetrate septum 16.
  • a collapsible liner 31 can be used in a container 29, eliminating the need for venting container 29. That is, as reagent is drawn from collapsible liner 31, no air is needed to equalize the pressure inside the liner and thus venting is un ⁇ necessary.
  • Container 29 is otherwise identical to con ⁇ tainers 11, 12 and 13 including septum 16 and threaded neck portion 14, the structure and function of which have been described in connection with Figs. 1 and 2.
  • the invention provides a safe contamination-free package for reagents to ensure
  • the removability of the con ⁇ tainers from the rack allows them to be placed into a storage rack if all the reagent is not used. Different size threads may be used on each container and corres ⁇ ponding cap. In this way correct placement of each con ⁇ tainer on the supporting rack may be assured. Alterna ⁇ tively, color coding could be used.
  • the resealable sep ⁇ tum prevents leakage when the containers are removed from the supporting rack.
  • the collapsible liner may also be made opaque such that- light-sensitive reagents may be protected.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

L'appareil de l'invention pour le stockage et la distribution d'un agent de réaction comprend des conteneurs (11, 12, 13) pourvus de septa élastomères (16) dans leurs embouchures (15). Lorsqu'ils sont fixés à un ratelier de support (19), une aiguille creuse (24) sur le ratelier de support (19) perce les septas élastomères (15) et permet la distribution de l'agent de réaction qui s'écoule des conteneurs (11, 12, 13) au travers de l'aiguille (24).
PCT/US1982/001194 1981-08-31 1982-08-31 Systeme de stockage et de distribution d'un agent de reaction WO1983000932A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29765081A 1981-08-31 1981-08-31
US297,650810831 1981-08-31

Publications (1)

Publication Number Publication Date
WO1983000932A1 true WO1983000932A1 (fr) 1983-03-17

Family

ID=23147195

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1982/001194 WO1983000932A1 (fr) 1981-08-31 1982-08-31 Systeme de stockage et de distribution d'un agent de reaction

Country Status (3)

Country Link
EP (1) EP0086833A1 (fr)
JP (1) JPS58501367A (fr)
WO (1) WO1983000932A1 (fr)

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0369722A1 (fr) * 1988-11-14 1990-05-23 Diversey Corporation Distributeur de produits liquides
DE3938559A1 (de) * 1989-11-21 1991-05-23 Boehringer Mannheim Gmbh Reagenzbevorratungssystem fuer ein medizinisches analysegeraet
EP0577343A2 (fr) * 1992-06-26 1994-01-05 Bio-Rad Laboratories, Inc. Récipient à réactifs et support de récipients pour analyseurs cliniques automatiques
WO1999004979A1 (fr) * 1997-07-23 1999-02-04 Marsh Company, An Illinois Corporation Bouteille d'encre a diaphragme de fermeture perforable
FR2781473A1 (fr) * 1998-07-27 2000-01-28 Ecolab Inc Appareil de distribution de fluide
US6095370A (en) * 1997-12-18 2000-08-01 Americlean Systems, Inc. Encapsulated liquid dispensing device and method
US6152327A (en) * 1998-11-12 2000-11-28 Americlean Systems, Inc. Dispensing method and device
US6193933B1 (en) * 1997-10-27 2001-02-27 Hitachi, Ltd. Automatic analysis apparatus
DE19837434C2 (de) * 1997-08-20 2001-05-17 Hitachi Ltd Automatische chemische Analyseeinrichtung
US6299299B1 (en) * 1997-03-07 2001-10-09 Encad, Inc. System and method for supplying ink to a printer
US6321941B1 (en) 2000-04-20 2001-11-27 The Procter & Gamble Company Consumer safe fitment for connecting a reservoir to a dispensing appliance
EP1099558A3 (fr) * 1999-11-09 2002-01-02 Illinois Tool Works Inc. Adaptateur et bouchon de connection de bouteille pour couplage de bouteilles à des alimentations en encre
US6386392B1 (en) 1999-11-02 2002-05-14 The Procter & Gamble Company Reservoirs for use with cleaning devices
US6390614B2 (en) * 2000-01-06 2002-05-21 Hewlett-Packard Company Fluid-jet print cartridge and method
US6685056B1 (en) 1999-08-05 2004-02-03 The Procter & Gamble Company Dispensing device comprising a reservoir and attachment means provided with protected piercing means
WO2010105650A2 (fr) * 2009-03-19 2010-09-23 Crinotec Gmbh Procédé et dispositif pour déterminer une teneur en matière étrangère dans une matrice
EP2319383A1 (fr) * 2009-11-05 2011-05-11 MEIKO Maschinenbau GmbH & Co. KG Lance d'aspiration et récipient doté d'une géométrie de codage
US8153061B2 (en) 2005-11-23 2012-04-10 Siemens Healthcare Diagnostics Inc. Storage and supply system for clinical solutions used in an automatic analyzer
WO2013019346A1 (fr) * 2011-07-29 2013-02-07 Corning Incorporated Dispositif de séparation magnétique et procédés associés
WO2013171004A1 (fr) * 2012-05-15 2013-11-21 Robert Bosch Gmbh Procédé d'introduction d'un échantillon dans un système microfluidique
DE102012216881A1 (de) * 2012-09-20 2014-03-20 Kba-Metronic Gmbh Druckeinrichtung
USD713931S1 (en) 2013-01-09 2014-09-23 Central Garden & Pet Company Sprayer
DE102013218952A1 (de) 2013-09-20 2015-03-26 Kba-Metronic Gmbh Druckeinrichtung
CN105944776A (zh) * 2016-07-13 2016-09-21 贵州大学 简易聚丙烯酰胺凝胶倒胶装置
WO2016178899A1 (fr) * 2015-05-01 2016-11-10 Abbott Laboratories Appareil pour retirer un contenu liquide présent dans un récipient
EP3026437B1 (fr) * 2013-07-26 2020-04-29 Sekisui Medical Co., Ltd. Appareil d'analyse d'échantillon

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105121294B (zh) 2013-03-13 2018-09-04 雅培实验室 用于容器的键控盖以及与其相关的装置和系统
USD886609S1 (en) 2013-12-20 2020-06-09 Abbott Laboratories Bottle cap
USD869276S1 (en) 2013-12-20 2019-12-10 Abbott Laboratories Bottle cap
USD881709S1 (en) 2013-12-20 2020-04-21 Abbott Laboratories Bottle with cap

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US2438024A (en) * 1946-01-26 1948-03-16 Stransky Joseph Milk bottle utility device
US2628130A (en) * 1949-01-15 1953-02-10 Knapp Monarch Co Spraying device
US2911123A (en) * 1956-07-23 1959-11-03 Saccomanno Geno Bottle cap
US3186599A (en) * 1963-10-15 1965-06-01 Evelyn S Levinson Dispenser for liquid in upright container with controlled atmosphere
US4063460A (en) * 1975-08-28 1977-12-20 Jan Axel Svensson Method for evacuating and then collecting medium samples in containers sealed by a resilient stopper at substantially atmospheric pressure
US4098431A (en) * 1977-01-13 1978-07-04 Cine Magnetics Inc. Chemical replenishing system
US4234103A (en) * 1978-03-31 1980-11-18 Baxter Travenol Laboratories, Inc. Diagnostic reagent dispensing bottle
US4236647A (en) * 1979-01-15 1980-12-02 Kotturan Paulson A Container for sterile liquids
US4306667A (en) * 1979-10-12 1981-12-22 The Coca-Cola Company Post-mix beverage dispensing system syrup package, valving system, and carbonator therefor

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2438024A (en) * 1946-01-26 1948-03-16 Stransky Joseph Milk bottle utility device
US2628130A (en) * 1949-01-15 1953-02-10 Knapp Monarch Co Spraying device
US2911123A (en) * 1956-07-23 1959-11-03 Saccomanno Geno Bottle cap
US3186599A (en) * 1963-10-15 1965-06-01 Evelyn S Levinson Dispenser for liquid in upright container with controlled atmosphere
US4063460A (en) * 1975-08-28 1977-12-20 Jan Axel Svensson Method for evacuating and then collecting medium samples in containers sealed by a resilient stopper at substantially atmospheric pressure
US4098431A (en) * 1977-01-13 1978-07-04 Cine Magnetics Inc. Chemical replenishing system
US4234103A (en) * 1978-03-31 1980-11-18 Baxter Travenol Laboratories, Inc. Diagnostic reagent dispensing bottle
US4236647A (en) * 1979-01-15 1980-12-02 Kotturan Paulson A Container for sterile liquids
US4306667A (en) * 1979-10-12 1981-12-22 The Coca-Cola Company Post-mix beverage dispensing system syrup package, valving system, and carbonator therefor

Cited By (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0369722A1 (fr) * 1988-11-14 1990-05-23 Diversey Corporation Distributeur de produits liquides
AU627791B2 (en) * 1988-11-14 1992-09-03 Diversey Ip International Bv Dispenser
DE3938559A1 (de) * 1989-11-21 1991-05-23 Boehringer Mannheim Gmbh Reagenzbevorratungssystem fuer ein medizinisches analysegeraet
EP0431352A2 (fr) * 1989-11-21 1991-06-12 Roche Diagnostics GmbH Système d'alimentation en réactifs pour analyseur clinique
EP0431352A3 (en) * 1989-11-21 1991-09-11 Boehringer Mannheim Gmbh Reagent storage and supply system for clinical analyzer
US5171538A (en) * 1989-11-21 1992-12-15 Boehringer Mannheim Gmbh Reagent supply system for a medical analytical instrument
EP0577343A2 (fr) * 1992-06-26 1994-01-05 Bio-Rad Laboratories, Inc. Récipient à réactifs et support de récipients pour analyseurs cliniques automatiques
EP0577343A3 (en) * 1992-06-26 1994-06-08 Bio Rad Laboratories Reagent receptacle and support rack for automated clinical analyzers
US6299299B1 (en) * 1997-03-07 2001-10-09 Encad, Inc. System and method for supplying ink to a printer
WO1999004979A1 (fr) * 1997-07-23 1999-02-04 Marsh Company, An Illinois Corporation Bouteille d'encre a diaphragme de fermeture perforable
US6079823A (en) * 1997-07-23 2000-06-27 Marconi Data Systems Inc. Ink bottle with puncturable diaphragm closure
DE19837434C2 (de) * 1997-08-20 2001-05-17 Hitachi Ltd Automatische chemische Analyseeinrichtung
US6599477B1 (en) 1997-08-20 2003-07-29 Hitachi, Ltd. Chemical analysis apparatus
US6193933B1 (en) * 1997-10-27 2001-02-27 Hitachi, Ltd. Automatic analysis apparatus
DE19849591C2 (de) * 1997-10-27 2001-07-19 Hitachi Ltd Automatisches Analysegerät
US6095370A (en) * 1997-12-18 2000-08-01 Americlean Systems, Inc. Encapsulated liquid dispensing device and method
FR2781473A1 (fr) * 1998-07-27 2000-01-28 Ecolab Inc Appareil de distribution de fluide
US6109480A (en) * 1998-07-27 2000-08-29 Ecolab Inc. Liquid dispenser and docking station for mating container
GB2339772A (en) * 1998-07-27 2000-02-09 Ecolab Inc Apparatus for dispensing fluid from a container
GB2339772B (en) * 1998-07-27 2003-02-26 Ecolab Inc LIquid dispenser and docking station for mating container
US6152327A (en) * 1998-11-12 2000-11-28 Americlean Systems, Inc. Dispensing method and device
US6685056B1 (en) 1999-08-05 2004-02-03 The Procter & Gamble Company Dispensing device comprising a reservoir and attachment means provided with protected piercing means
US6386392B1 (en) 1999-11-02 2002-05-14 The Procter & Gamble Company Reservoirs for use with cleaning devices
EP1099558A3 (fr) * 1999-11-09 2002-01-02 Illinois Tool Works Inc. Adaptateur et bouchon de connection de bouteille pour couplage de bouteilles à des alimentations en encre
US6390614B2 (en) * 2000-01-06 2002-05-21 Hewlett-Packard Company Fluid-jet print cartridge and method
US6321941B1 (en) 2000-04-20 2001-11-27 The Procter & Gamble Company Consumer safe fitment for connecting a reservoir to a dispensing appliance
US8153061B2 (en) 2005-11-23 2012-04-10 Siemens Healthcare Diagnostics Inc. Storage and supply system for clinical solutions used in an automatic analyzer
WO2010105650A2 (fr) * 2009-03-19 2010-09-23 Crinotec Gmbh Procédé et dispositif pour déterminer une teneur en matière étrangère dans une matrice
DE102009013534A1 (de) * 2009-03-19 2010-09-23 Crinotec Gmbh Verfahren und Vorrichtung zur Bestimmung eines Fremdstoffgehalts in einer Matrix
WO2010105650A3 (fr) * 2009-03-19 2010-12-02 Crinotec Gmbh Procédé et dispositif pour déterminer une teneur en matière étrangère dans une matrice
EP2319383A1 (fr) * 2009-11-05 2011-05-11 MEIKO Maschinenbau GmbH & Co. KG Lance d'aspiration et récipient doté d'une géométrie de codage
US9242250B2 (en) 2011-07-29 2016-01-26 Corning Incorporated Magnetic separation device and methods
WO2013019346A1 (fr) * 2011-07-29 2013-02-07 Corning Incorporated Dispositif de séparation magnétique et procédés associés
WO2013171004A1 (fr) * 2012-05-15 2013-11-21 Robert Bosch Gmbh Procédé d'introduction d'un échantillon dans un système microfluidique
DE102012216881A1 (de) * 2012-09-20 2014-03-20 Kba-Metronic Gmbh Druckeinrichtung
WO2014044805A1 (fr) 2012-09-20 2014-03-27 Kba-Metronic Gmbh Dispositif d'impression
USD713931S1 (en) 2013-01-09 2014-09-23 Central Garden & Pet Company Sprayer
EP3026437B1 (fr) * 2013-07-26 2020-04-29 Sekisui Medical Co., Ltd. Appareil d'analyse d'échantillon
DE102013218952A1 (de) 2013-09-20 2015-03-26 Kba-Metronic Gmbh Druckeinrichtung
WO2016178899A1 (fr) * 2015-05-01 2016-11-10 Abbott Laboratories Appareil pour retirer un contenu liquide présent dans un récipient
US9823263B2 (en) 2015-05-01 2017-11-21 Abbott Laboratories Apparatus for removing liquid contents of a container having a key activated sliding lock and method therefore
US10416181B2 (en) 2015-05-01 2019-09-17 Abbott Laboratories Apparatus for removing liquid contents of a container having a key activated sliding lock and method therefore
EP3974843A1 (fr) * 2015-05-01 2022-03-30 Abbott Laboratories Appareil d'élimination de contenus liquides d'un récipient
US11293936B2 (en) 2015-05-01 2022-04-05 Abbott Laboratories Apparatus for removing liquid contents of a container having a key activated sliding lock
US11899031B2 (en) 2015-05-01 2024-02-13 Abbott Laboratories Apparatus for removing liquid contents of a container
CN105944776A (zh) * 2016-07-13 2016-09-21 贵州大学 简易聚丙烯酰胺凝胶倒胶装置

Also Published As

Publication number Publication date
JPS58501367A (ja) 1983-08-18
EP0086833A1 (fr) 1983-08-31

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