UY39127A - Materiales y métodos para modular la inmunidad mediada por cadena delta - Google Patents

Materiales y métodos para modular la inmunidad mediada por cadena delta

Info

Publication number
UY39127A
UY39127A UY0001039127A UY39127A UY39127A UY 39127 A UY39127 A UY 39127A UY 0001039127 A UY0001039127 A UY 0001039127A UY 39127 A UY39127 A UY 39127A UY 39127 A UY39127 A UY 39127A
Authority
UY
Uruguay
Prior art keywords
methods
materials
antibodies
delta chain
immunity mediated
Prior art date
Application number
UY0001039127A
Other languages
English (en)
Inventor
Sanjaya Singh
Rajkumar Ganesan
S Grewal Iqbal
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of UY39127A publication Critical patent/UY39127A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Se describen anticuerpos multiespecíficos anti-TRDV2 o fragmentos de unión a antígeno de los mismos . También se describen los ácidos nucleicos que codifican los anticuerpos, las composiciones que comprenden los anticuerpos, los métodos para producir los anticuerpos y los métodos para usar los anticuerpos para tratar o prevenir enfermedades.
UY0001039127A 2020-03-13 2021-03-12 Materiales y métodos para modular la inmunidad mediada por cadena delta UY39127A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202062989111P 2020-03-13 2020-03-13

Publications (1)

Publication Number Publication Date
UY39127A true UY39127A (es) 2021-09-30

Family

ID=77664333

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001039127A UY39127A (es) 2020-03-13 2021-03-12 Materiales y métodos para modular la inmunidad mediada por cadena delta

Country Status (11)

Country Link
US (1) US20210284730A1 (es)
EP (1) EP4118121A4 (es)
JP (1) JP2023518189A (es)
KR (1) KR20220154190A (es)
CN (1) CN115605512A (es)
AU (1) AU2021234327A1 (es)
CA (1) CA3175134A1 (es)
IL (1) IL296358A (es)
TW (1) TW202144416A (es)
UY (1) UY39127A (es)
WO (1) WO2021183845A1 (es)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE273713T1 (de) * 1996-10-31 2004-09-15 Mochida Pharm Co Ltd Fas-antagonist für die prophylaxe oder therapie von gvhd
BR112014015018A2 (pt) * 2011-12-19 2020-10-27 Synimmune Gmbh moléculas de anticorpo biespecífico e seu método de produção, bem como composição farmacêutica e molécula de ácido nucleico
IL298041A (en) * 2015-08-17 2023-01-01 Janssen Pharmaceutica Nv Anti-bcma antibodies, bispecific antigen-binding molecules that bind bcma and cd3 and their uses
CN109089419B (zh) * 2015-11-25 2024-03-01 威特拉公司 April的抗体分子及其应用
WO2017197347A1 (en) * 2016-05-12 2017-11-16 Adicet Bio, Inc. METHODS FOR SELECTIVE EXPANSION OF γδ T-CELL POPULATIONS AND COMPOSITIONS THEREOF
EP3793599A1 (en) * 2018-05-16 2021-03-24 Janssen Biotech, Inc. Bcma/cd3 and gprdc5d/cd3 bispecific antibodies for use in cancer therapy

Also Published As

Publication number Publication date
IL296358A (en) 2022-11-01
CA3175134A1 (en) 2021-09-16
CN115605512A (zh) 2023-01-13
EP4118121A1 (en) 2023-01-18
AU2021234327A1 (en) 2022-10-06
KR20220154190A (ko) 2022-11-21
TW202144416A (zh) 2021-12-01
EP4118121A4 (en) 2024-05-15
JP2023518189A (ja) 2023-04-28
US20210284730A1 (en) 2021-09-16
WO2021183845A1 (en) 2021-09-16

Similar Documents

Publication Publication Date Title
CY1122994T1 (el) Μεθοδος καθαρισμου κανναβινοειλων, συνθεσεων και kit αυτων
CL2020003028A1 (es) Anticuerpos anti-cd33, anticuerpos bispecíficos anti-cd33/anti-cd3 y sus usos.
PE20210167A1 (es) Proteinas de union multiespecificas y mejoras con estas
CO2019009432A2 (es) Nuevas moléculas de unión a antígeno biespecíficas capaces de unirse específicamente a cd40 y a fap.
CO2021003900A2 (es) Moléculas de unión a antígeno biespecíficas que comprenden el clon 212 anti-fap
AR110526A1 (es) Anticuerpos anti-ox40 y sus usos en el tratamiento del cáncer
CO7061039A2 (es) Anticuerpos dirigidos contra metaloproteinasas de matriz 9
HN2009000614A (es) Inhibidores nucleosidicos del hvc
UY39415A (es) Métodos y composiciones para modular la inmunidad mediada por cadenas beta
AR127513A2 (es) Anticuerpos de cadena pesada multiespecíficos con regiones constantes de cadena pesada modificadas
CL2019002368A1 (es) Composiciones y métodos para el tratamiento de cáncer.
DOP2022000229A (es) Anticuerpos de cadena pesada multiespecíficos con regiones constantes de cadena pesada modificadas
CO7061040A2 (es) Anticuerpos contra la metaloproteinasa de la matriz 9
CY1125552T1 (el) Μεθοδος για την παρασκευη ουσιαστικα διαστερεομερικως καθαρου φωσφοροδιαμιδικου ολιγομερους, φωσφοροδιαμιδικου ολιγομερους που παρασκευαζεται με τετοια μεθοδο και φαρμακευτικη συνθεση αποτελουμενη απο τετοιο φωσφοροδιαμιδικο ολιγομερες
PE20181176A1 (es) Composiciones biofarmaceuticas
ECSP20042489A (es) Anticuerpos de cadena pesada que se unen a cd22
PE20230160A1 (es) Anticuerpos especificos para cd47, pd-l1 y sus usos
CO2022001222A2 (es) Materiales y métodos para fragmentos variables de cadena única mejorados
UY39416A (es) Moléculas de direccionamiento inmunes multiespecíficas y usos de estas
BR112022027101A2 (pt) Anticorpos multiespecíficos que se ligam a bcma
CO2019009815A2 (es) Combinaciones farmacéuticas
EA201891664A1 (ru) Составы/композиции, содержащие ингибитор btk
UY39699A (es) Anticuerpos anti-tau y usos de estos
UY39127A (es) Materiales y métodos para modular la inmunidad mediada por cadena delta
CO2021015998A2 (es) Materiales y métodos para modular la inmunidad mediada por células t