UY38134A - Reducción de la producción de acetato mediante levadura que sobreexpresa pab1 - Google Patents

Reducción de la producción de acetato mediante levadura que sobreexpresa pab1

Info

Publication number
UY38134A
UY38134A UY38134A UY38134A UY38134A UY 38134 A UY38134 A UY 38134A UY 38134 A UY38134 A UY 38134A UY 38134 A UY38134 A UY 38134A UY 38134 A UY38134 A UY 38134A
Authority
UY
Uruguay
Prior art keywords
pab1
yeast
reduction
acetate production
over expressing
Prior art date
Application number
UY38134A
Other languages
English (en)
Inventor
Johanna Maria Teunissen Paula
Qun Zhu Quinn
Min Qi
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Publication of UY38134A publication Critical patent/UY38134A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/54—Acetic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Se describen composiciones y métodos relacionados con levaduras modificadas que sobreexpresan en exceso la proteína de unión a poliadenilato (PAB1). La levadura produce una cantidad disminuida de acetato en comparación con las células parentales. Dicha levadura es particularmente útil para la producción de etanol a gran escala a partir de sustratos de almidón en los que el acetato está en un producto final no deseado.
UY38134A 2018-03-06 2019-03-06 Reducción de la producción de acetato mediante levadura que sobreexpresa pab1 UY38134A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862639183P 2018-03-06 2018-03-06

Publications (1)

Publication Number Publication Date
UY38134A true UY38134A (es) 2019-10-31

Family

ID=65802188

Family Applications (1)

Application Number Title Priority Date Filing Date
UY38134A UY38134A (es) 2018-03-06 2019-03-06 Reducción de la producción de acetato mediante levadura que sobreexpresa pab1

Country Status (12)

Country Link
US (1) US11447783B2 (es)
EP (1) EP3762499B1 (es)
CN (1) CN112041449B (es)
AR (1) AR114132A1 (es)
BR (1) BR112020018055A2 (es)
DK (1) DK3762499T5 (es)
ES (1) ES2973502T3 (es)
HU (1) HUE065696T2 (es)
PL (1) PL3762499T3 (es)
RS (1) RS65389B1 (es)
UY (1) UY38134A (es)
WO (1) WO2019173204A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115552016A (zh) * 2019-11-26 2022-12-30 丹尼斯科美国公司 通过过表达mig多肽的酵母来降低乙酸生产
WO2022069613A1 (en) 2020-09-30 2022-04-07 Lonza Ltd Host cells overexpressing translational factors

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985575A (en) 1998-05-20 1999-11-16 Wisconsin Alumni Research Foundation Tethered function assay for protein function
US6018106A (en) * 1998-07-16 2000-01-25 University Of Kentucky Research Foundation Use of yeast poly (A) binding proteins and their genes for broad range protection of plants against bacterial, fungal and viral pathogens
US6610508B1 (en) * 1999-03-08 2003-08-26 Anadys Pharmaceuticals, Inc. Translation driver system and methods for use thereof
CN1339506A (zh) * 2000-08-23 2002-03-13 上海博德基因开发有限公司 一种新的多肽——人多聚腺苷酸结合蛋白20.13和编码这种多肽的多核苷酸
AU2004289953B2 (en) * 2003-06-18 2008-09-25 Genelux Corporation Modified recombinant vaccina viruses and other microorganisms, uses thereof
EP2060632A1 (en) 2007-10-29 2009-05-20 Technische Universität Berlin Method of modifying a yeast cell for the production of ethanol
EP2277989A1 (en) 2009-07-24 2011-01-26 Technische Universiteit Delft Fermentative glycerol-free ethanol production
US8956851B2 (en) 2011-04-05 2015-02-17 Lallemand Hungary Liquidity Management, LLC Methods for the improvement of product yield and production in a microorganism through the addition of alternate electron acceptors
ES2699747T3 (es) * 2011-04-29 2019-02-12 Danisco Us Inc Microorganismos recombinantes para la producción potenciada de mevalonato, isopreno e isoprenoides
JP6295512B2 (ja) * 2012-03-15 2018-03-20 株式会社豊田中央研究所 酵母における外来遺伝子の発現産物の生産方法、酵母における発現調節剤及びその利用
CA2903053C (en) 2013-03-15 2023-01-17 Amyris, Inc. Use of phosphoketolase and phosphotransacetylase for production of acetyl-coenzyme a derived compounds
CA2920114A1 (en) 2013-08-15 2015-02-19 Lallemand Hungary Liquidity Management Llc Methods for the improvement of product yield and production in a microorganism through glycerol recycling
WO2015065871A1 (en) 2013-10-28 2015-05-07 Danisco Us Inc. Large scale genetically engineered active dry yeast
EP3122876B1 (en) 2014-03-28 2020-11-25 Danisco US Inc. Altered host cell pathway for improved ethanol production
BR112018072150A2 (pt) 2016-04-28 2019-02-12 Danisco Us Inc. equilíbrio de redox em levedura

Also Published As

Publication number Publication date
HUE065696T2 (hu) 2024-06-28
CN112041449B (zh) 2024-07-05
US20200407734A1 (en) 2020-12-31
DK3762499T5 (da) 2024-08-26
PL3762499T3 (pl) 2024-06-24
ES2973502T3 (es) 2024-06-20
EP3762499A1 (en) 2021-01-13
US11447783B2 (en) 2022-09-20
AR114132A1 (es) 2020-07-22
CN112041449A (zh) 2020-12-04
EP3762499B1 (en) 2023-12-20
DK3762499T3 (da) 2024-03-11
WO2019173204A1 (en) 2019-09-12
RS65389B1 (sr) 2024-04-30
BR112020018055A2 (pt) 2020-12-29

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20240513