DK3762499T3 - Reduktion i acetatproduktion ved hjælp af gær, der overudtrykker pab1 - Google Patents

Reduktion i acetatproduktion ved hjælp af gær, der overudtrykker pab1 Download PDF

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Publication number
DK3762499T3
DK3762499T3 DK19711486.1T DK19711486T DK3762499T3 DK 3762499 T3 DK3762499 T3 DK 3762499T3 DK 19711486 T DK19711486 T DK 19711486T DK 3762499 T3 DK3762499 T3 DK 3762499T3
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DK
Denmark
Prior art keywords
pab1
reduction
acetate production
yeast overexpressing
overexpressing
Prior art date
Application number
DK19711486.1T
Other languages
English (en)
Inventor
Min Qi
Paula Johanna Maria Teunissen
Quinn Qun Zhu
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Application granted granted Critical
Publication of DK3762499T3 publication Critical patent/DK3762499T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/54Acetic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56Lactic acid
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK19711486.1T 2018-03-06 2019-03-04 Reduktion i acetatproduktion ved hjælp af gær, der overudtrykker pab1 DK3762499T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862639183P 2018-03-06 2018-03-06
PCT/US2019/020526 WO2019173204A1 (en) 2018-03-06 2019-03-04 Reduction in acetate production by yeast over-expressing pab1

Publications (1)

Publication Number Publication Date
DK3762499T3 true DK3762499T3 (da) 2024-03-11

Family

ID=65802188

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19711486.1T DK3762499T3 (da) 2018-03-06 2019-03-04 Reduktion i acetatproduktion ved hjælp af gær, der overudtrykker pab1

Country Status (9)

Country Link
US (1) US11447783B2 (da)
EP (1) EP3762499B1 (da)
CN (1) CN112041449A (da)
AR (1) AR114132A1 (da)
BR (1) BR112020018055A2 (da)
DK (1) DK3762499T3 (da)
RS (1) RS65389B1 (da)
UY (1) UY38134A (da)
WO (1) WO2019173204A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4065718A1 (en) * 2019-11-26 2022-10-05 Danisco US Inc. Reduction in acetate production by yeast over-expressing mig polypeptides
CN116490517A (zh) 2020-09-30 2023-07-25 龙沙有限公司 过表达翻译因子的宿主细胞

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985575A (en) 1998-05-20 1999-11-16 Wisconsin Alumni Research Foundation Tethered function assay for protein function
US6018106A (en) * 1998-07-16 2000-01-25 University Of Kentucky Research Foundation Use of yeast poly (A) binding proteins and their genes for broad range protection of plants against bacterial, fungal and viral pathogens
US6610508B1 (en) * 1999-03-08 2003-08-26 Anadys Pharmaceuticals, Inc. Translation driver system and methods for use thereof
CN1339506A (zh) * 2000-08-23 2002-03-13 上海博德基因开发有限公司 一种新的多肽——人多聚腺苷酸结合蛋白20.13和编码这种多肽的多核苷酸
ATE420160T1 (de) * 2003-06-18 2009-01-15 Genelux Corp Modifizierte rekombinante vacciniaviren, verwendungen davon
EP2060632A1 (en) 2007-10-29 2009-05-20 Technische Universität Berlin Method of modifying a yeast cell for the production of ethanol
EP2277989A1 (en) 2009-07-24 2011-01-26 Technische Universiteit Delft Fermentative glycerol-free ethanol production
CN103649321B (zh) 2011-04-05 2019-07-16 拉勒曼德匈牙利流动性管理有限责任公司 用于通过添加交替电子受体改善微生物中的产品收率和产量的方法
EP2702140B1 (en) 2011-04-29 2018-10-31 Danisco US Inc. Recombinant microorganisms for enhanced production of mevalonate, isoprene, and isoprenoids
JP6295512B2 (ja) * 2012-03-15 2018-03-20 株式会社豊田中央研究所 酵母における外来遺伝子の発現産物の生産方法、酵母における発現調節剤及びその利用
US9410214B2 (en) * 2013-03-15 2016-08-09 Amyris, Inc. Use of phosphoketolase and phosphotransacetylase for production of acetyl-coenzyme A derived compounds
FI3033413T4 (fi) 2013-08-15 2023-08-31 Menetelmiä tuotesaannon ja tuotannon parantamiseksi mikro-organismissa glyserolikierrätyksellä
EP3063263A1 (en) 2013-10-28 2016-09-07 Danisco US Inc. Large scale genetically engineered active dry yeast
EP3122876B1 (en) 2014-03-28 2020-11-25 Danisco US Inc. Altered host cell pathway for improved ethanol production
EP3448988A1 (en) 2016-04-28 2019-03-06 Danisco US Inc. Redox balancing in yeast

Also Published As

Publication number Publication date
UY38134A (es) 2019-10-31
WO2019173204A1 (en) 2019-09-12
AR114132A1 (es) 2020-07-22
BR112020018055A2 (pt) 2020-12-29
CN112041449A (zh) 2020-12-04
EP3762499B1 (en) 2023-12-20
RS65389B1 (sr) 2024-04-30
EP3762499A1 (en) 2021-01-13
US11447783B2 (en) 2022-09-20
US20200407734A1 (en) 2020-12-31

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