UY35544A - Complejos de bis azainositol hafnio para adquisición de imágenes por rayos x - Google Patents

Complejos de bis azainositol hafnio para adquisición de imágenes por rayos x

Info

Publication number
UY35544A
UY35544A UY0001035544A UY35544A UY35544A UY 35544 A UY35544 A UY 35544A UY 0001035544 A UY0001035544 A UY 0001035544A UY 35544 A UY35544 A UY 35544A UY 35544 A UY35544 A UY 35544A
Authority
UY
Uruguay
Prior art keywords
complexes
hafnio
acquisition
ray images
azainositol
Prior art date
Application number
UY0001035544A
Other languages
English (en)
Inventor
Dr Thomas Frenzel
Dr Keith Graham
Dr Christian Neis
Prof Dr Kaspar Hegetschweiler
Dr Hubertus Pietsch
Dr Detlev Sülzle
Dr Markus Berger
Dr Gregor Jost
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of UY35544A publication Critical patent/UY35544A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/76—Metal complexes of amino carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Measurement Of Radiation (AREA)

Abstract

La presente invención describe una nueva clase de complejos trinucleares de hafnio que comprenden dos ligandos de ácido carboxílico hexadentados de azainositol, métodos para su preparación y su uso como agentes de contraste para rayos X.
UY0001035544A 2013-04-25 2014-04-25 Complejos de bis azainositol hafnio para adquisición de imágenes por rayos x UY35544A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20130165281 EP2796152A1 (en) 2013-04-25 2013-04-25 Unsymmetrical Bis Azainositol Hafnium Complexes for X-Ray Imaging
US201361817126P 2013-04-29 2013-04-29

Publications (1)

Publication Number Publication Date
UY35544A true UY35544A (es) 2014-11-28

Family

ID=48190213

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001035544A UY35544A (es) 2013-04-25 2014-04-25 Complejos de bis azainositol hafnio para adquisición de imágenes por rayos x

Country Status (9)

Country Link
US (1) US20160060209A1 (es)
EP (2) EP2796152A1 (es)
JP (1) JP2016519112A (es)
CN (1) CN105142679A (es)
AR (1) AR096091A1 (es)
CA (1) CA2910226A1 (es)
HK (1) HK1211861A1 (es)
UY (1) UY35544A (es)
WO (1) WO2014173857A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115386097B (zh) * 2022-08-18 2024-01-26 上海市第六人民医院 一种铪基金属有机框架材料及其制备方法和造影成像应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3503614A1 (de) 1985-02-02 1986-08-07 Laboratorien Hausmann AG, St. Gallen All-cis-1,3,5-triamino-2,4,6-cyclohexantriol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate
GB8900719D0 (en) 1989-01-13 1989-03-08 Nycomed As Compounds
CH679742A5 (es) 1990-01-09 1992-04-15 Byk Gulden Lomberg Chem Fab
DE4028139A1 (de) 1990-09-05 1992-03-12 Hausmann Ag Labor Verwendung der komplexe radioaktiver metallionen mit all-cis-1,3,5-triamino-2,4,6-cyclohexantriol und seinen derivaten fuer roentgendiagnostische zwecke und in der tumortherapie sowie zur herstellung von mitteln fuer roentgendiagnostische zwecke und fuer die tumortherapie
DE10057009A1 (de) * 2000-11-17 2002-05-29 Celanese Ventures Gmbh Non-Metallocene, Verfahren zur Herstellung von diesen und deren Verwendung zur Polymerisation von Olefinen
FR2944106B1 (fr) * 2009-04-03 2012-09-28 Erytech Pharma Methode de dosage de l'inositol hexaphosphate (ihp).
WO2012080290A1 (en) 2010-12-15 2012-06-21 General Electric Company Nanoparticle composition and associated methods thereof
EP2540321A1 (en) 2011-06-30 2013-01-02 Bayer Intellectual Property GmbH Bis Tridentate W3O2 Clusters for X-Ray imaging
CN104321082A (zh) * 2012-05-18 2015-01-28 拜耳医药股份有限公司 用于x射线成像的双氮杂肌醇重金属络合物

Also Published As

Publication number Publication date
EP2988787A1 (en) 2016-03-02
US20160060209A1 (en) 2016-03-03
CN105142679A (zh) 2015-12-09
AR096091A1 (es) 2015-12-02
JP2016519112A (ja) 2016-06-30
EP2796152A1 (en) 2014-10-29
HK1211861A1 (en) 2016-06-03
WO2014173857A1 (en) 2014-10-30
CA2910226A1 (en) 2014-10-30

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20211206