UY33511A - Procedimiento de obtención de la forma cristalina ii del febuxostat - Google Patents

Procedimiento de obtención de la forma cristalina ii del febuxostat

Info

Publication number
UY33511A
UY33511A UY0001033511A UY33511A UY33511A UY 33511 A UY33511 A UY 33511A UY 0001033511 A UY0001033511 A UY 0001033511A UY 33511 A UY33511 A UY 33511A UY 33511 A UY33511 A UY 33511A
Authority
UY
Uruguay
Prior art keywords
febuxostat
obtaining
procedure
crystal form
crystallization
Prior art date
Application number
UY0001033511A
Other languages
English (en)
Inventor
Francisco Marquillas Olondriz
Josep Salaet Ferre
Original Assignee
Interquim Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Interquim Sa filed Critical Interquim Sa
Publication of UY33511A publication Critical patent/UY33511A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La invención se refiere a un nuevo procedimiento de obtención de la forma cristalina II del Febuxostat por cristalización en un disolvente elegido entre acetato de etilo, acetato de metilo o formiato de etilo.
UY0001033511A 2010-07-13 2011-07-13 Procedimiento de obtención de la forma cristalina ii del febuxostat UY33511A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES201031061 2010-07-13

Publications (1)

Publication Number Publication Date
UY33511A true UY33511A (es) 2012-01-31

Family

ID=44533538

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001033511A UY33511A (es) 2010-07-13 2011-07-13 Procedimiento de obtención de la forma cristalina ii del febuxostat

Country Status (7)

Country Link
US (1) US20130184466A1 (es)
EP (1) EP2593442A1 (es)
JP (1) JP2013531021A (es)
AR (2) AR081267A1 (es)
TW (1) TW201217346A (es)
UY (1) UY33511A (es)
WO (1) WO2012007487A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2619191A4 (en) 2010-09-24 2014-03-26 Hetero Research Foundation NEW POLYMORPHS OF FEBUXOSTAT
WO2012168948A2 (en) 2011-06-06 2012-12-13 Hetero Research Foundation Process for febuxostat
JP2014533297A (ja) * 2011-11-15 2014-12-11 マイラン ラボラトリーズ リミテッドＭｙｌａｎ Ｌａｂｏｒａｔｏｒｉｅｓ Ｌｉｍｉｔｅｄ フェブキソスタットの多形の調製方法
EP2692342A1 (en) 2012-07-30 2014-02-05 Interquim, S.A. Process for the preparation of pharmaceutical compositions comprising febuxostat in the form of tablets
EP3002006A1 (en) 2014-10-01 2016-04-06 Bluepharma - Industria Farmacêutica, S.A. Pharmaceutical composition capable for the incorporation Febuxostat in the crystalline modifications F10, II, G and A
CN110526879B (zh) * 2019-08-28 2022-06-21 迪嘉药业集团有限公司 一种小粒度非布司他的结晶制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU218942B (hu) * 1990-11-30 2001-01-29 Teijin Ltd. 2-Fenil-tiazol-származékok, az ezeket tartalmazó gyógyászati készítmények, valamint eljárás a vegyületek előállítására
CN101139325B (zh) 2006-09-07 2010-05-12 上海医药工业研究院 2-(3-氰基-4-异丁氧基苯基)-4-甲基-5-噻唑甲酸晶型及其制备方法
CN100546985C (zh) * 2007-06-29 2009-10-07 上海华拓医药科技发展股份有限公司 非布他特微晶及其组合物
CN101412700B (zh) 2007-10-19 2011-06-08 上海医药工业研究院 非布司他的晶型及其制备方法

Also Published As

Publication number Publication date
EP2593442A1 (en) 2013-05-22
TW201217346A (en) 2012-05-01
AR081659A1 (es) 2012-10-10
JP2013531021A (ja) 2013-08-01
WO2012007487A1 (en) 2012-01-19
US20130184466A1 (en) 2013-07-18
AR081267A1 (es) 2012-07-18
WO2012007487A9 (en) 2012-06-21

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