UY33316A - Compuestos de cefemo que contienen seudocatecol - Google Patents

Compuestos de cefemo que contienen seudocatecol

Info

Publication number
UY33316A
UY33316A UY0001033316A UY33316A UY33316A UY 33316 A UY33316 A UY 33316A UY 0001033316 A UY0001033316 A UY 0001033316A UY 33316 A UY33316 A UY 33316A UY 33316 A UY33316 A UY 33316A
Authority
UY
Uruguay
Prior art keywords
bacteria
compounds
cepheme
provides
present
Prior art date
Application number
UY0001033316A
Other languages
English (en)
Inventor
Yamawaki Kenji
Sugimoto Hideki
Sano Masayuki
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of UY33316A publication Critical patent/UY33316A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente invención proporciona compuestos de cefemo que exhiben un potente espectro antimicrobiano contra una variedad de bacterias incluyendo bacterias Gram negativas y/o bacterias Gram positivas. Preferentemente, la presente invención proporciona compuestos de cefemo que exhiben una potente actividad antimicrobiana contra las bacterias Gram negativas productoras de beta-lactamasa. Más preferentemente, la presente invención proporciona compuestos de cefemo que exhiben una potente actividad antimicrobiana contra bacterias productoras de metalo-beta-lactamasa del tipo de la Clase B. Un compuesto de fórmula: o un éster, una sal farmacéuticamente aceptable, o un solvato del mismo.
UY0001033316A 2010-04-05 2011-04-05 Compuestos de cefemo que contienen seudocatecol UY33316A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2010087130 2010-04-05

Publications (1)

Publication Number Publication Date
UY33316A true UY33316A (es) 2011-10-31

Family

ID=44762901

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001033316A UY33316A (es) 2010-04-05 2011-04-05 Compuestos de cefemo que contienen seudocatecol

Country Status (7)

Country Link
US (1) US8883773B2 (es)
JP (1) JP5852559B2 (es)
CN (1) CN102918047A (es)
AR (1) AR081757A1 (es)
TW (1) TW201139450A (es)
UY (1) UY33316A (es)
WO (1) WO2011125966A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009049086A1 (en) 2007-10-09 2009-04-16 Larry Sutton Broad spectrum beta-lactamase inhibitors
AU2009310959B2 (en) * 2008-10-31 2015-05-07 Shionogi & Co., Ltd. Cephalosporin having catechol group
MX2012011521A (es) 2010-04-05 2013-03-08 Shionogi & Co Compuestos cefem que tienen un grupo catecol.
WO2011136268A1 (ja) * 2010-04-28 2011-11-03 塩野義製薬株式会社 新規なセフェム誘導体
CA2833121A1 (en) 2011-04-28 2012-11-01 Shionogi & Co., Ltd. Novel cephem compound having catechol or pseudo-catechol structure
WO2013002215A1 (ja) 2011-06-27 2013-01-03 塩野義製薬株式会社 ピリジニウム基を有するセフェム化合物
WO2013051597A1 (ja) 2011-10-04 2013-04-11 塩野義製薬株式会社 カテコール基を有するセフェム誘導体
TWI547496B (zh) 2011-10-04 2016-09-01 葛蘭素集團公司 抗菌化合物
US9527866B2 (en) 2012-10-29 2016-12-27 Shionogi & Co., Ltd. Processes for production of intermediates for 2-alkyl cephem compounds
UY35103A (es) * 2012-10-29 2014-05-30 Glaxo Group Ltd Compuestos de cefem 2-sustituidos
CN106661052B (zh) * 2014-09-04 2021-05-11 盐野义制药株式会社 头孢菌素衍生物的中间体及其制造方法
US9751894B2 (en) 2015-12-10 2017-09-05 Naeja-Rgm Pharmaceuticals Inc. Cephem compounds, their production and use
CN107556328B (zh) * 2016-07-01 2020-10-09 正大天晴药业集团股份有限公司 制备头孢烯化合物的中间体及其晶体
WO2018227178A1 (en) * 2017-06-09 2018-12-13 Fob Synthesis, Inc. Carbapenem compounds and compositions for the treatment of bacterial infections
AU2021210472A1 (en) * 2020-01-22 2022-07-21 Jiangsu Hengrui Medicine Co., Ltd. Cephalosporin antibacterial compound and pharmaceutical application thereof
CN113024581A (zh) * 2020-03-04 2021-06-25 刀鹏 一种盐酸头孢吡肟的合成方法
US20240132518A1 (en) * 2021-01-12 2024-04-25 Shanghai Senhui Medicine Co., Ltd. Cephalosporin antibacterial compound and preparation method therefor

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JPS57118588A (en) 1981-11-26 1982-07-23 Toyama Chem Co Ltd Novel cephalosporin
US4670431A (en) 1983-01-21 1987-06-02 Beecham Group P.L.C. Beta-lactam antibacterial agents
EP0168177A3 (en) 1984-06-28 1987-04-01 Pfizer Limited Cephalosporin antibiotics
DE3688477T2 (de) 1985-03-01 1993-09-16 Takeda Chemical Industries Ltd Antibakterielle verbindungen, ihre herstellung und verwendung.
JPH068300B2 (ja) 1985-08-02 1994-02-02 萬有製薬株式会社 新規セフアロスポリン誘導体
EP0211656A3 (en) 1985-08-10 1988-03-09 Beecham Group Plc Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them
EP0214600B1 (en) 1985-09-03 1992-12-02 Otsuka Kagaku Kabushiki Kaisha Cephalosporin derivatives
JPS62158291A (ja) 1986-01-07 1987-07-14 Sagami Chem Res Center セフアロスポリン誘導体
DE3750411T2 (de) 1986-04-14 1995-03-16 Banyu Pharma Co Ltd Cephalosporinderivate, Verfahren zu ihrer Herstellung und antibakterielle Präparate.
ATE92927T1 (de) 1986-04-14 1993-08-15 Banyu Pharma Co Ltd 1-carboxy-1-vinyloxyiminoaminothiazolcephalosporin-derivate und deren herstellung.
IE61679B1 (en) * 1987-08-10 1994-11-16 Fujisawa Pharmaceutical Co Water-soluble antibiotic composition and water-soluble salts of new cephem compounds
GB8719875D0 (en) 1987-08-22 1987-09-30 Beecham Group Plc Compounds
JPH0228185A (ja) 1988-04-14 1990-01-30 Tanabe Seiyaku Co Ltd セファロスポリン化合物及びその合成中間体
US5149803A (en) 1988-05-10 1992-09-22 Imperial Chemical Industries Plc Intermediates for cephalosporin compounds
US5244890A (en) 1988-06-06 1993-09-14 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
PH25965A (en) 1988-06-06 1992-01-13 Fujisawa Pharmaceutical Co New cephem compounds which have antimicrobial activities
GB8813945D0 (en) 1988-06-13 1988-07-20 Fujisawa Pharmaceutical Co New cephem compounds & process for preparation thereof
GB8817653D0 (en) 1988-07-25 1988-09-01 Fujisawa Pharmaceutical Co New cephem compounds & processes for preparation thereof
US5143910A (en) * 1989-09-07 1992-09-01 Shionogi & Co., Ltd. Piperaziniocephalosporins
GB9005246D0 (en) 1990-03-08 1990-05-02 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
US5126336A (en) 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
US5194433A (en) 1990-11-13 1993-03-16 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
GB9111406D0 (en) * 1991-05-28 1991-07-17 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
GB9118672D0 (en) 1991-08-30 1991-10-16 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
EP0628562A1 (fr) 1993-06-10 1994-12-14 Roussel Uclaf Céphalosporines comportant en position 7 un radical oxymino substitué, leurs intermédiaires, leurs procédé de préparation et leur application comme médicaments
AU1694099A (en) 1997-12-26 1999-07-19 Cheil Jedang Corporation Cephem derivatives and a method for producing the compounds and an antibacterialcomposition containing the compounds
TW200305422A (en) 2002-03-18 2003-11-01 Shionogi & Co Broad spectrum cefem compounds
US6713625B2 (en) 2002-05-23 2004-03-30 Orchid Chemicals & Pharmaceuticals Ltd. Process for the preparation of cefditoren using the thioester of thiazolylacetic acid
JP3928086B2 (ja) 2005-03-29 2007-06-13 塩野義製薬株式会社 ３−プロペニルセフェム誘導体
WO2007096740A2 (en) 2006-02-20 2007-08-30 Orchid Research Laboratories Limited Novel cephalosporins
JP2009530228A (ja) 2006-03-16 2009-08-27 アステラス製薬株式会社 セフェム化合物および抗菌薬としての利用
AU2009310959B2 (en) * 2008-10-31 2015-05-07 Shionogi & Co., Ltd. Cephalosporin having catechol group
MX2012011521A (es) 2010-04-05 2013-03-08 Shionogi & Co Compuestos cefem que tienen un grupo catecol.
WO2011136268A1 (ja) 2010-04-28 2011-11-03 塩野義製薬株式会社 新規なセフェム誘導体

Also Published As

Publication number Publication date
WO2011125966A1 (ja) 2011-10-13
AR081757A1 (es) 2012-10-17
CN102918047A (zh) 2013-02-06
TW201139450A (en) 2011-11-16
JPWO2011125966A1 (ja) 2013-07-11
US20130079319A1 (en) 2013-03-28
JP5852559B2 (ja) 2016-02-03
US8883773B2 (en) 2014-11-11

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Legal Events

Date Code Title Description
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Effective date: 20191218