UY31978A - Derivados de 1-bencil-cinolin-4-(1h)-ona sustituidos, su preparación y su aplicación en terapéutica - Google Patents

Derivados de 1-bencil-cinolin-4-(1h)-ona sustituidos, su preparación y su aplicación en terapéutica

Info

Publication number
UY31978A
UY31978A UY0001031978A UY31978A UY31978A UY 31978 A UY31978 A UY 31978A UY 0001031978 A UY0001031978 A UY 0001031978A UY 31978 A UY31978 A UY 31978A UY 31978 A UY31978 A UY 31978A
Authority
UY
Uruguay
Prior art keywords
cinolin
bencil
preparation
application
therapeutics
Prior art date
Application number
UY0001031978A
Other languages
English (en)
Inventor
Claude Vernhet
Rinaldi-Carmona Murielle
Elodie Barbagallo
Pascale Roux
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of UY31978A publication Critical patent/UY31978A/es

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    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/28—Cinnolines
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
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Abstract

La presente invención se refiere a los compuestos DERIVADOS DE 1-BENCIL-CINOLIN-4-(1H)-ONA SUSTITUIDOS que responden a la fórmula (I) que tienen afinidad por los receptores CB2 de los cannabinoides, en la que los radicales y sustituyentes son tales como se especifican en la Memoria Descriptiva y en las Reivindicaciones, su preparación o su aplicación en el dolor, enfermedades inflamatorias, auto-inmunes, alérgicas, infecciosas, neurodegenerativas, cardiovasculares, gastro-intestinales, cánceres, obesidad, diabetes de tipo II, resistencia a la insulina e inflamación del tejido adiposo.
UY0001031978A 2008-07-11 2009-07-10 Derivados de 1-bencil-cinolin-4-(1h)-ona sustituidos, su preparación y su aplicación en terapéutica UY31978A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0803974A FR2933697B1 (fr) 2008-07-11 2008-07-11 Derives de 1-benzyl-cinnolin-4-(1h)-one substitues, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
UY31978A true UY31978A (es) 2010-02-26

Family

ID=40344933

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001031978A UY31978A (es) 2008-07-11 2009-07-10 Derivados de 1-bencil-cinolin-4-(1h)-ona sustituidos, su preparación y su aplicación en terapéutica

Country Status (21)

Country Link
US (1) US8410099B2 (es)
EP (1) EP2313376B1 (es)
JP (1) JP5490113B2 (es)
KR (1) KR20110036931A (es)
CN (1) CN102149689A (es)
AR (1) AR074629A1 (es)
AU (1) AU2009269836A1 (es)
BR (1) BRPI0915884A2 (es)
CA (1) CA2729896A1 (es)
CL (1) CL2011000045A1 (es)
CO (1) CO6331466A2 (es)
EA (1) EA201170183A1 (es)
FR (1) FR2933697B1 (es)
IL (1) IL210529A0 (es)
MA (1) MA32543B1 (es)
MX (1) MX2011000441A (es)
NZ (1) NZ590426A (es)
TW (1) TW201002681A (es)
UY (1) UY31978A (es)
WO (1) WO2010004215A2 (es)
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US9150588B2 (en) 2010-08-10 2015-10-06 Takeda Pharmaceutical Company Limited Substituted pyridazin-4(1H)-ones as phosphodiesterase 10A inhibitors
KR101719565B1 (ko) * 2014-10-02 2017-03-24 한국화학연구원 광산화환원 촉매와 CF3SO2Cl을 사용한 알켄 화합물의 클로로트리플루오로메틸레이션 방법

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US5532237A (en) 1995-02-15 1996-07-02 Merck Frosst Canada, Inc. Indole derivatives with affinity for the cannabinoid receptor
FR2735774B1 (fr) 1995-06-21 1997-09-12 Sanofi Sa Utilisation de composes agonistes du recepteur cb2 humain pour la preparation de medicaments immunomodulateurs, nouveaux composes agonistes du recepteur cb2 et les compositions pharmaceutiques les contenant
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EA201170183A1 (ru) 2011-08-30
EP2313376A2 (fr) 2011-04-27
ZA201100251B (en) 2012-04-25
JP5490113B2 (ja) 2014-05-14
CN102149689A (zh) 2011-08-10
FR2933697B1 (fr) 2010-08-13
US20110144115A1 (en) 2011-06-16
KR20110036931A (ko) 2011-04-12
AU2009269836A1 (en) 2010-01-14
MA32543B1 (fr) 2011-08-01
AR074629A1 (es) 2011-02-02
IL210529A0 (en) 2011-03-31
JP2011527323A (ja) 2011-10-27
US8410099B2 (en) 2013-04-02
EP2313376B1 (fr) 2014-12-24
MX2011000441A (es) 2011-04-04
CL2011000045A1 (es) 2011-06-17
WO2010004215A2 (fr) 2010-01-14
NZ590426A (en) 2012-04-27
BRPI0915884A2 (pt) 2015-11-03
TW201002681A (en) 2010-01-16
CA2729896A1 (fr) 2010-01-14
FR2933697A1 (fr) 2010-01-15
CO6331466A2 (es) 2011-10-20
WO2010004215A3 (fr) 2010-03-04

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