UY30351A1 - Cocristal maleato de 2-{etil[3-((4-((5-(2-3-fluorofenil)amino]-2-oxoetil}-1h-pirazol-3-il)amino)quinazolin-7-il)oxi)propil)amino]etil dihidrogeno fosfato, procesos de preparacion, composiciones y aplicaciones - Google Patents

Cocristal maleato de 2-{etil[3-((4-((5-(2-3-fluorofenil)amino]-2-oxoetil}-1h-pirazol-3-il)amino)quinazolin-7-il)oxi)propil)amino]etil dihidrogeno fosfato, procesos de preparacion, composiciones y aplicaciones

Info

Publication number
UY30351A1
UY30351A1 UY30351A UY30351A UY30351A1 UY 30351 A1 UY30351 A1 UY 30351A1 UY 30351 A UY30351 A UY 30351A UY 30351 A UY30351 A UY 30351A UY 30351 A1 UY30351 A1 UY 30351A1
Authority
UY
Uruguay
Prior art keywords
amino
quinazolin
fluorophenyl
dihydrogen phosphate
oxoetil
Prior art date
Application number
UY30351A
Other languages
English (en)
Spanish (es)
Inventor
George Joseph Sependa
Richard Storey
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36637528&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY30351(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY30351A1 publication Critical patent/UY30351A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
UY30351A 2006-05-16 2007-05-15 Cocristal maleato de 2-{etil[3-((4-((5-(2-3-fluorofenil)amino]-2-oxoetil}-1h-pirazol-3-il)amino)quinazolin-7-il)oxi)propil)amino]etil dihidrogeno fosfato, procesos de preparacion, composiciones y aplicaciones UY30351A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0609621.8A GB0609621D0 (en) 2006-05-16 2006-05-16 Novel co-crystal

Publications (1)

Publication Number Publication Date
UY30351A1 true UY30351A1 (es) 2008-01-02

Family

ID=36637528

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30351A UY30351A1 (es) 2006-05-16 2007-05-15 Cocristal maleato de 2-{etil[3-((4-((5-(2-3-fluorofenil)amino]-2-oxoetil}-1h-pirazol-3-il)amino)quinazolin-7-il)oxi)propil)amino]etil dihidrogeno fosfato, procesos de preparacion, composiciones y aplicaciones

Country Status (22)

Country Link
US (1) US7625910B2 (https=)
EP (1) EP2027114A1 (https=)
JP (1) JP2009537498A (https=)
KR (1) KR20090009297A (https=)
CN (1) CN101448823A (https=)
AR (1) AR060963A1 (https=)
AU (1) AU2007251304A1 (https=)
BR (1) BRPI0712791A2 (https=)
CA (1) CA2650519A1 (https=)
CL (1) CL2007001388A1 (https=)
EC (1) ECSP088890A (https=)
GB (1) GB0609621D0 (https=)
IL (1) IL194862A0 (https=)
MX (1) MX2008014550A (https=)
NO (1) NO20084580L (https=)
RU (1) RU2008149242A (https=)
SA (1) SA07280243B1 (https=)
TW (1) TW200813026A (https=)
UA (1) UA95108C2 (https=)
UY (1) UY30351A1 (https=)
WO (1) WO2007132227A1 (https=)
ZA (1) ZA200809172B (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60234125D1 (de) * 2001-12-24 2009-12-03 Astrazeneca Ab E inhibitoren
MXPA05012377A (es) * 2003-05-15 2006-05-25 Arqule Inc Derivados de imidazotiazoles e imidazoxazol como inhibidores de p38.
JP2008517064A (ja) * 2004-10-19 2008-05-22 アークル インコーポレイテッド Ｐ３８ｍａｐキナーゼのイミダゾオキサゾールおよびイミダゾチアゾール阻害剤の合成
EP2013218A2 (en) * 2006-04-17 2009-01-14 Arqule, Inc. Raf inhibitors and their uses
CN102317293A (zh) * 2008-12-05 2012-01-11 艾科尔公司 Raf抑制剂及其用途
HUE024568T2 (hu) * 2009-09-11 2016-02-29 Amgen Inc N-(4-((3-(2-amino-4-pirimidinil)-2-piridinil)oxi)fenil)-4-(4-metil-2-tienil)-1-ftalazinamin antimitotikus szerre rezisztens rák kezelésében történõ alkalmazásra
GB201007286D0 (en) 2010-04-30 2010-06-16 Astex Therapeutics Ltd New compounds
GB201020179D0 (en) 2010-11-29 2011-01-12 Astex Therapeutics Ltd New compounds
GB201118652D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201118675D0 (en) 2011-10-28 2011-12-14 Astex Therapeutics Ltd New compounds
GB201118656D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201118654D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201209613D0 (en) 2012-05-30 2012-07-11 Astex Therapeutics Ltd New compounds
GB201209609D0 (en) 2012-05-30 2012-07-11 Astex Therapeutics Ltd New compounds
GB201307577D0 (en) 2013-04-26 2013-06-12 Astex Therapeutics Ltd New compounds
ES2640648T3 (es) * 2013-09-16 2017-11-03 Astrazeneca Ab Nanopartículas poliméricas terapéuticas y métodos para su fabricación y uso
JO3512B1 (ar) 2014-03-26 2020-07-05 Astex Therapeutics Ltd مشتقات كينوكسالين مفيدة كمعدلات لإنزيم fgfr كيناز
JP6752715B2 (ja) 2014-03-26 2020-09-09 アステックス、セラピューティックス、リミテッドＡｓｔｅｘ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｌｉｍｉｔｅｄ 組合せ
MX373150B (es) 2014-03-26 2020-04-21 Astex Therapeutics Ltd Combinaciones de un inhibidor del factor de crecimiento de fibroblasto (fgfr) y un inhibidor del receptor del factor de crecimiento 1 similar a insulina (igf1r).
TWI719960B (zh) 2015-02-10 2021-03-01 英商阿斯迪克治療公司 新穎組成物
US10478494B2 (en) 2015-04-03 2019-11-19 Astex Therapeutics Ltd FGFR/PD-1 combination therapy for the treatment of cancer
AU2016328693B2 (en) 2015-09-23 2021-03-11 Janssen Pharmaceutica Nv Bi-heteroaryl substituted 1,4-benzodiazepines and uses thereof for the treatment of cancer
DK3353177T3 (da) 2015-09-23 2020-08-24 Janssen Pharmaceutica Nv Tricykliske heterocykler til behandling af cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60234125D1 (de) * 2001-12-24 2009-12-03 Astrazeneca Ab E inhibitoren
ES2290529T3 (es) * 2002-12-24 2008-02-16 Astrazeneca Ab Derivados de fosfonooxiquinazolina y su uso farmaceutico.

Also Published As

Publication number Publication date
ZA200809172B (en) 2009-12-30
JP2009537498A (ja) 2009-10-29
CL2007001388A1 (es) 2008-01-18
IL194862A0 (en) 2009-08-03
RU2008149242A (ru) 2010-06-27
AR060963A1 (es) 2008-07-23
UA95108C2 (en) 2011-07-11
MX2008014550A (es) 2008-11-27
EP2027114A1 (en) 2009-02-25
BRPI0712791A2 (pt) 2012-09-04
WO2007132227A1 (en) 2007-11-22
CA2650519A1 (en) 2007-11-22
TW200813026A (en) 2008-03-16
US7625910B2 (en) 2009-12-01
KR20090009297A (ko) 2009-01-22
ECSP088890A (es) 2008-12-30
GB0609621D0 (en) 2006-06-21
SA07280243B1 (ar) 2010-12-01
CN101448823A (zh) 2009-06-03
NO20084580L (no) 2009-02-05
AU2007251304A1 (en) 2007-11-22
US20080045481A1 (en) 2008-02-21

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Effective date: 20120606