UY29624A1 - NON-STEROID PROGESTERONE RECEPTOR MODULATORS - Google Patents

NON-STEROID PROGESTERONE RECEPTOR MODULATORS

Info

Publication number
UY29624A1
UY29624A1 UY29624A UY29624A UY29624A1 UY 29624 A1 UY29624 A1 UY 29624A1 UY 29624 A UY29624 A UY 29624A UY 29624 A UY29624 A UY 29624A UY 29624 A1 UY29624 A1 UY 29624A1
Authority
UY
Uruguay
Prior art keywords
receptor modulators
progesterone receptor
prevention
compounds
steroid progesterone
Prior art date
Application number
UY29624A
Other languages
Spanish (es)
Inventor
Ulrich Bothe
Peter Droescher
Ulrike Fuhrmann
Alexander Hillisch
Guenter Kaufmann
Carsten Moller
Norbert Schmees
Wolfgang Schwede
Lothar Sobek
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of UY29624A1 publication Critical patent/UY29624A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/02—1,2-Oxazines; Hydrogenated 1,2-oxazines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a moduladores no esteroides de receptor de progesterona de la fórmula general, a su uso para la preparación de medicamentos y a las composiciones farmacéuticas que contienen estos compuestos. Los compuestos de la invención son apropiados para la terapia y la prevención de enfermedades ginecológicas, como endometriosos, leiomiomas del útero, sangrados disfuncionales y dismenorrea y para el tratamiento y la prevención de tumores hormona-dependientes y para el control de la fertilidad femenina, así como para la terapia de sustitución hormonal.The present invention relates to non-steroidal progesterone receptor modulators of the general formula, their use for the preparation of medicaments and the pharmaceutical compositions containing these compounds. The compounds of the invention are suitable for the therapy and prevention of gynecological diseases, such as endometrious, uterine leiomyomas, dysfunctional bleeding and dysmenorrhea and for the treatment and prevention of hormone-dependent tumors and for the control of female fertility, as well. As for hormone replacement therapy.

UY29624A 2005-06-24 2006-06-26 NON-STEROID PROGESTERONE RECEPTOR MODULATORS UY29624A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005030292A DE102005030292A1 (en) 2005-06-24 2005-06-24 Nonsteroidal progesterone receptor modulators

Publications (1)

Publication Number Publication Date
UY29624A1 true UY29624A1 (en) 2007-01-31

Family

ID=37199176

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29624A UY29624A1 (en) 2005-06-24 2006-06-26 NON-STEROID PROGESTERONE RECEPTOR MODULATORS

Country Status (22)

Country Link
EP (1) EP1902049A2 (en)
JP (1) JP2008543910A (en)
KR (1) KR20080030622A (en)
CN (1) CN101248066A (en)
AR (1) AR054519A1 (en)
AU (1) AU2006261048A1 (en)
BR (1) BRPI0611903A2 (en)
CA (1) CA2611897A1 (en)
CR (1) CR9598A (en)
DE (1) DE102005030292A1 (en)
DO (1) DOP2006000148A (en)
EA (1) EA200702524A1 (en)
EC (1) ECSP078044A (en)
GT (1) GT200600271A (en)
IL (1) IL188021A0 (en)
MX (1) MX2008000072A (en)
NO (1) NO20080440L (en)
PE (1) PE20070125A1 (en)
TW (1) TW200740778A (en)
UY (1) UY29624A1 (en)
WO (1) WO2006136461A2 (en)
ZA (1) ZA200800690B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY30805A1 (en) * 2006-12-21 2008-07-31 Bayer Schering Pharma Ag NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS
DE102007032800A1 (en) * 2007-07-10 2009-01-15 Bayer Schering Pharma Aktiengesellschaft Nonsteroidal progesterone receptor modulators
DE102007058747A1 (en) 2007-12-05 2009-06-10 Bayer Schering Pharma Aktiengesellschaft Nonsteroidal progesterone receptor modulators
WO2010002075A1 (en) * 2008-07-02 2010-01-07 Pharmacostech Co., Ltd. Methods for preparing amide derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19856475A1 (en) * 1998-11-27 2000-05-31 Schering Ag Nonsteroidal anti-inflammatories
EP1344776A1 (en) * 2002-03-11 2003-09-17 Schering Aktiengesellschaft 5- 2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino -phtalide and 6- 2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino -4-methyl-2,3-benzoxazin-1-one derivatives with progesterone receptor modulating activity for use in fertility control, hormone replacement therapy and the treatment of gynecological disorders
BRPI0412231A (en) * 2003-07-01 2006-08-22 Schering Ag heterocyclically substituted pentanol derivatives, processes for their preparation and application as inflammation inhibitors

Also Published As

Publication number Publication date
ECSP078044A (en) 2008-01-23
NO20080440L (en) 2008-03-25
JP2008543910A (en) 2008-12-04
MX2008000072A (en) 2008-03-24
TW200740778A (en) 2007-11-01
GT200600271A (en) 2007-02-05
PE20070125A1 (en) 2007-02-14
EP1902049A2 (en) 2008-03-26
DOP2006000148A (en) 2007-07-15
EA200702524A1 (en) 2008-06-30
KR20080030622A (en) 2008-04-04
CA2611897A1 (en) 2006-12-28
DE102005030292A1 (en) 2007-01-11
ZA200800690B (en) 2009-09-30
BRPI0611903A2 (en) 2010-10-05
AU2006261048A1 (en) 2006-12-28
WO2006136461A2 (en) 2006-12-28
WO2006136461A3 (en) 2007-03-15
CN101248066A (en) 2008-08-20
IL188021A0 (en) 2008-03-20
AR054519A1 (en) 2007-06-27
CR9598A (en) 2008-04-09

Similar Documents

Publication Publication Date Title
CU20120175A7 (en) COMPOUNDS DERIVED FROM 6,7-DIHIDRO-5H-BENZO [7] ANNULARS
CR10875A (en) DERIVATIVES OF ESTER AND AMIDA OF INDAZOLILO FOR THE TREATMENT OF DISEASES MEDIATED BY A GLUCOCORTICOID RECEPTOR
ECSP055685A (en) NEW COMPOUNDS OF ISOTIAZOL AND ISOXAZOL AS INHIBITORS OF THE TRANSFORMING GROWTH FACTOR (TGF)
SV2010003580A (en) NEW AGONISTS OF GLUCOCORTICOID RECEPTORS
CR10489A (en) PHENYL-PIRAZOL DERIVATIVES AS LEGANDS OF NON-STEROID GLUCOCORTICOID RECEPTORS
ECSP18047708A (en) 17-HYDROXY-17-PENTAFLUOROETHYL-ESTRA-4,9 (10) -DIEN-11-ARYL DERIVATIVES AS PROGESTERONE ANTAGONISTS AND PROCEDURES FOR THEIR PREPARATION
ECSP034428A (en) CYCLOPENTHANOLS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND THEIR USE
CU20140064A7 (en) DERIVATIVES OF 6,7- DIHIDRO-5H-BENZO [7] CANCELLATION, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL PRODUCTS THAT INCLUDE THE SAME AND ITS USE IN THE PREPARATION OF MEDICINES
UY29626A1 (en) NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS
CL2009000445A1 (en) Compounds derived from piperidine 1,4 heterocycle substituted, procedure to prepare these compounds, pharmaceutical composition comprising them and their use for pain therapy and the treatment of diseases such as Alzheimer's, schizophrenia, anxiety and depression.
UY29625A1 (en) USE OF NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS
UY29624A1 (en) NON-STEROID PROGESTERONE RECEPTOR MODULATORS
GT200600335A (en) PROGESTERONE CIANOPIRROL-FENIL AMIDA RECEIVER MODULATORS AND USES OF THE SAME
CR9627A (en) CYANOPYRROLE-SULFONAMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF
UY30805A1 (en) NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS
UY30815A1 (en) NON-STEROID MODULATORS OF THE PROGESTERONE RECEIVER
TH85615A (en) Non-steroidal progesterone receptor modulators
DOP2003000719A (en) NEW COMPOUNDS OF ISOTIAZOL AND ISOXAZOL AS INHIBITORS OF THE TRANSFORMING GROWTH FACTOR (TGF)
CR7748A (en) NEW PIRAZOL COMPOUNDS AS INHIBITORS OF THE TRANSFORMING GROWTH FACTOR (TGF)
CU20090109A7 (en) INDAZOLIL ESTER AND AMIDA DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY A GLUCOCORTICOID RECEPTOR

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20160831