UY26133A1 - SUBSTITUTED DERIVATIVE OF PYRAZOLE. - Google Patents

SUBSTITUTED DERIVATIVE OF PYRAZOLE.

Info

Publication number
UY26133A1
UY26133A1 UY26133A UY26133A UY26133A1 UY 26133 A1 UY26133 A1 UY 26133A1 UY 26133 A UY26133 A UY 26133A UY 26133 A UY26133 A UY 26133A UY 26133 A1 UY26133 A1 UY 26133A1
Authority
UY
Uruguay
Prior art keywords
pyrazole
substituted derivative
medicine
obtaining
formula
Prior art date
Application number
UY26133A
Other languages
Spanish (es)
Inventor
Alexander Straub
Achim Feurer
Cristina Alonso-Alija
Elke Stahl
Johannes-Peter Stasch
Elisabeth Perzborn
Klaus Dembowsky
Armin Kern
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of UY26133A1 publication Critical patent/UY26133A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a un derivado sustituido de pirazol de fórmula (I), a un procedimiento para su obtención y a su uso como medicamento, especialmente para el tratamiento de afecciones cardiovasculares.The present invention relates to a substituted pyrazole derivative of formula (I), to a process for obtaining it and to using it as a medicine, especially for the treatment of cardiovascular conditions.

UY26133A 1999-05-04 2000-04-28 SUBSTITUTED DERIVATIVE OF PYRAZOLE. UY26133A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19920352A DE19920352A1 (en) 1999-05-04 1999-05-04 Substituted pyrazole derivative

Publications (1)

Publication Number Publication Date
UY26133A1 true UY26133A1 (en) 2000-12-29

Family

ID=7906844

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26133A UY26133A1 (en) 1999-05-04 2000-04-28 SUBSTITUTED DERIVATIVE OF PYRAZOLE.

Country Status (6)

Country Link
AU (1) AU4554500A (en)
DE (1) DE19920352A1 (en)
GT (1) GT200000062A (en)
PE (1) PE20010111A1 (en)
UY (1) UY26133A1 (en)
WO (1) WO2000066582A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10021069A1 (en) * 2000-04-28 2001-10-31 Bayer Ag Substituted pyrazole derivative
AR031176A1 (en) * 2000-11-22 2003-09-10 Bayer Ag NEW DERIVATIVES OF PIRAZOLPIRIDINA SUBSTITUTED WITH PIRIDINE
DE10122894A1 (en) * 2001-05-11 2002-11-14 Bayer Ag New pyrazolo(3,4-b)pyridin-3-yl)-5-pyrimidinyl sulfonates, are soluble guanyl cyclase stimulants useful e.g. for treating cardiovascular, thromboembolic or central nervous system diseases
ITMI20011308A1 (en) * 2001-06-21 2002-12-21 Nicox Sa DRUGS FOR CHRONIC PAIN
DE10132416A1 (en) * 2001-07-04 2003-01-16 Bayer Ag New morpholine-bridged pyrazolopyridine derivatives
DE10217799A1 (en) * 2002-04-22 2003-11-06 Bayer Ag stents
DE10242941A1 (en) * 2002-09-16 2004-03-18 Bayer Ag New 2-(pyrazolo-(3,4-b)-pyridinyl)-5-pyridinyl-4-pyrimidinylamine derivative, is a soluble guanylate cyclase stimulant useful e.g. for treating cardiovascular diseases, hypertension or ischemia
DE102007028319A1 (en) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituted oxazolidinones and their use
DE102007028407A1 (en) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituted oxazolidinones and their use
DE102007028406A1 (en) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituted oxazolidinones and their use
DE102007028320A1 (en) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituted oxazolidinones and their use
EP2138178A1 (en) 2008-06-28 2009-12-30 Bayer Schering Pharma Aktiengesellschaft Oxazolidninones for the treatment fo chronic obstructive pulmonary disease (COPD) and/or asthma
EA031602B1 (en) 2011-11-25 2019-01-31 Адверио Фарма Гмбх Processes for preraring aldehydes
EP2847228B1 (en) 2012-05-10 2018-07-25 Bayer Pharma Aktiengesellschaft Antibodies capable of binding to the coagulation factor xi and/or its activated form factor xia and uses thereof
EA201891416A1 (en) 2015-12-14 2018-12-28 Айронвуд Фармасьютикалз, Инк. APPLICATION of sGC STIMULATORS FOR THE TREATMENT OF GASTRIC AND INTESTINAL SPINKLIN TREATMENT
EP3554488A2 (en) 2016-12-13 2019-10-23 Cyclerion Therapeutics, Inc. Use of sgc stimulators for the treatment of esophageal motility disorders
KR102615821B1 (en) 2017-04-11 2023-12-21 선샤인 레이크 파르마 컴퍼니 리미티드 Fluorine-substituted indazole compounds and uses thereof
JP2021530491A (en) 2018-07-11 2021-11-11 サイクレリオン・セラピューティクス，インコーポレーテッド Use of sGC stimulants for the treatment of mitochondrial disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19649460A1 (en) * 1996-11-26 1998-05-28 Bayer Ag New substituted pyrazole derivatives
DE19834047A1 (en) * 1998-07-29 2000-02-03 Bayer Ag Substituted pyrazole derivatives

Also Published As

Publication number Publication date
PE20010111A1 (en) 2001-04-12
WO2000066582A1 (en) 2000-11-09
GT200000062A (en) 2001-10-26
DE19920352A1 (en) 2000-11-09
AU4554500A (en) 2000-11-17

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20100518