USRE40833E1 - Medicinal product with a textile component - Google Patents

Medicinal product with a textile component Download PDF

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Publication number
USRE40833E1
USRE40833E1 US11/436,184 US43618400A USRE40833E US RE40833 E1 USRE40833 E1 US RE40833E1 US 43618400 A US43618400 A US 43618400A US RE40833 E USRE40833 E US RE40833E
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US
United States
Prior art keywords
medical product
hole pattern
openings
embroidered
layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
US11/436,184
Other languages
English (en)
Inventor
Erich Wintermantel
Jorg Mayer
Erdal Karamuk
Roland Seidl
Barbel Wagner
Bernhard Bischoff
Mario Billia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BISCHOFF TEXTIL AG
Original Assignee
Tissupor AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tissupor AG filed Critical Tissupor AG
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Publication of USRE40833E1 publication Critical patent/USRE40833E1/en
Assigned to BISCHOFF TEXTIL AG reassignment BISCHOFF TEXTIL AG ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: TISSUPOR AG
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A61F13/01008—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/06—Bandages or dressings; Absorbent pads specially adapted for feet or legs; Corn-pads; Corn-rings
    • A61F13/064—Bandages or dressings; Absorbent pads specially adapted for feet or legs; Corn-pads; Corn-rings for feet
    • A61F13/069—Decubitus ulcer bandages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00089—Wound bandages
    • A61F2013/00238—Wound bandages characterised by way of knitting or weaving
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00089—Wound bandages
    • A61F2013/00314—Wound bandages with surface treatments
    • A61F2013/00327—Wound bandages with surface treatments to create projections or depressions in surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00544—Plasters form or structure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24273—Structurally defined web or sheet [e.g., overall dimension, etc.] including aperture
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24355—Continuous and nonuniform or irregular surface on layer or component [e.g., roofing, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24479—Structurally defined web or sheet [e.g., overall dimension, etc.] including variation in thickness

Definitions

  • the invention relates to a medical product with a textile component, for example a wound compress, having the features of a multiplicity of openings, with at least two patterns of holes with groups of openings, the diameter of one opening of one hole pattern deviating from the diameter of an opening of another hole pattern in each case by about at least a factor of 5 from one another.
  • a textile component for example a wound compress
  • wound compresses consist for example of woven fabric, which has the disadvantage that it has a hard surface which adapts poorly to the wound. For this reason, many wound compresses are made up of knitted fabrics which are soft per se. They also have some degree of moisture absorbency. The softness of knitted fabrics arises from the movement of the threads within the interfacing. These abovementioned wound products have the disadvantage that they harden because of exudates emerging from the wound and thus lose their functional ability.
  • EP 870 820 discloses a nonadhesive wound dressing which, across its active area, has depressions containing a pharmaceutical carrier substance. The depressions are intended only for receiving and delivering an active substance. The nonadhesion of the wound dressing is emphasized.
  • EP 931 012 describes a compress which is used for treating wounds in a moist environment and which, by means of an appropriate choice of dressing material, is likewise intended not to adhere to the wound.
  • a further aim of the invention is to ensure that the rigidness of such a medical product can be preset individually at the time of production.
  • this object is achieved by the fact that the surface has a multiplicity of openings, there being at least two patterns of holes with groups of openings, the diameter of one opening of one hole pattern deviating from the diameter of an opening of another hole pattern in each case by about at least a factor of 5 from one another.
  • the advantage for the patient of using medical products according to the invention lies in the more rapid wound healing, in the reduction of the pain associated with wound treatment, in the shorter time spent in an inpatient department, and in the fact that the cost of treating such wounds is considerably reduced, which is important to the economy.
  • Mechanical signals in the form of the exertion of a controlled pull on the cells in the wound bed can represent an important activator of the wound response.
  • Mechanical influences on the wound also play a part in collagen genesis because modified stresses during wound closure influence scarring. It is assumed that in order to form a normal collagen architecture a defined physiological mechanical stimulation is required with respect to loading and orientation. In the case of scar tissue, by contrast, the anisotropy of the collagen network and the dimensions of the collagen fibers are increased.
  • the invention makes available a wound treatment system developed on a textile basis which controls tissue formation and positively influences angiogenesis by acting as a framework.
  • the support for the layer according to the invention is dependent on the application.
  • the use of the medical products according to the invention is possible in many areas.
  • One area of use concerns the treatment of large wounds, burns or in surgical applications, for example for hernia meshes. These procedures require treatment systems which make it possible to minimize scar formation.
  • the medical products it is also possible for the medical products to include mannose-6-phosphate or other collagen-regulating means, or factors which promote tissue regeneration, for example growth factors of the TGF-b family.
  • the medical product can be used in many applications where the embroidery-specific properties such as the controlled mechanical properties of an embroidery, the local variation in the mechanical design and the specific porosity can be of great advantage.
  • these include abdominal wall replacements, artificial blood vessels and artificial ligaments.
  • the embroidery technique can be used to pass from a first specific structure, where the ligament is to grow on and where load transmission takes place, to a second and different structure in the ligament area.
  • a further application is the formation of augmentation embroideries for reconstruction of the jaw bone in the dental sector.
  • different yarn types are used. These can include fibrous, multifilament or monofilament yarns, which can also be untreated, antimicrobially pretreated, gel-coated and can be present in different titers.
  • the knot size and the nature of the linking can likewise be preset.
  • FIG. 1 is a diagrammatic cross section through a medical article according to one illustrative embodiment of the invention
  • FIG. 2 is a diagrammatic plan view of a portion of the embroidered surface of a medical article according to the invention.
  • FIG. 3 is an enlarged sectional view of the area of a pore according to FIG. 2 .
  • FIG. 1 shows a medical article 1 according to the invention in a diagrammatic cross section.
  • This medical article is made up of three layers, for example.
  • a base layer remote from the wound consists of compact woven fabric 10 which has an antibacterial action. This also controls the oxygen and water content at the same time.
  • a spacer layer 11 with high shear force takeup consisting of gel-modified yarns permits absorption and desorption and the mechanical binding of the compress material.
  • the shear force takeup permits the distribution of local pressure loads, that is to say it has a cushion function and permits stress distribution, which leads to uniform loading of the wound surface and thus avoids negative local stresses.
  • the compress 1 has an embroidered layer 12 .
  • the fabric 11 is designed as a spacer in relation to the antibacterial layer 10 and as a material which takes up exudate.
  • this fabric 11 which is advantageously formed as a knit, lies the separately produced embroidered layer 12 which is preferably connected at its side edges to the compress 1 , for example by ultrasonic welding.
  • Reference number 13 denotes stimulation points which are formed in the layer 12 , particularly in the embroidery technique. In the form represented, they form flat to semi-round protuberances, stimulation points 13 , facing toward the wound surface and they can also protrude from the side facing away from the wound surface.
  • the stimulation points 13 can all be the same size or can differ in size individually or in groups.
  • size in this case refers both to the height above and below the surface of the embroidery and also to the surface area in the plan view of the figures. Gradients in size can be provided, for example with the stimulation points 13 with the largest surface area and the smallest thickness in the middle of an embroidery, and the stimulation points 13 with the smallest surface area and the greatest thickness at the edges of the embroidery. Any other combination of thicknesses and surface areas can be used.
  • An embroidered structure 12 and thus an angiopolar layer is thus provided near the wound.
  • An angiopolar layer is a layer which permits the specific oriented growth of blood vessels into a structure and thus influences the density and orientation of the blood vessels in the regenerated tissue.
  • This embroidered structure 12 introduces morphological features into wound treatment which induce and stimulate a specific angiogenesis within the framework and thus form the physiological basis for tissue renewal.
  • the textile architecture 11 and 12 creates optimum mechanical support, forms a reservoir for exudates and permits optimum control of moisture and gas transport.
  • the embroidery technique With the embroidery technique, highly architectured three-dimensional textile structures are obtained which are needed for structural functions, for example pore pattern, for angiogenesis.
  • the embroidery technique permits any desired use of materials in base fabrics.
  • FIG. 2 shows a diagrammatic plan view of a portion of the embroidered surface 12 of a medical article 1 according to the invention.
  • the structures designated with reference number 14 are openings which are provided in the embroidered pattern and which are substantially diamond-shaped here. In other configurations, these shapes can also be rectangular, round, elliptic or have another shape.
  • the openings at the center of the compress 1 have the greatest aperture area and form corresponding cavities.
  • a gradient is provided with which the diameters 17 of the openings provided decrease from the center to the edges.
  • the openings 14 are arranged in a regular pattern in the illustrative embodiment shown.
  • the embroidery technology also permits an irregular arrangement of the openings 14 according to further objectives, in particular with a variation in size.
  • the fabric 11 mentioned with reference to FIG. 1 and lying behind the embroidered surface 12 acts as a spacer and distributes the weight upon loading in order to prevent decubitus ulcers.
  • the predetermined hole cross sections 17 have a size forming a cavity suitable for a blood coagulum. They are therefore a support for the tissue-regenerating element.
  • the embroidered surface of which FIG. 3 shows a section of the area of a pore 14 according to FIG. 2 , has mesoscopic openings 24 in addition to the apertures or pores 14 .
  • the macroscopic apertures or pores 14 are produced by a plurality of links and have a size of the order of 1 to 2 millimeters edge length. They serve for ingrowth of tissue plugs and as a reservoir for the blood coagulum from the freshly bleeding wound.
  • the mesoscopic openings 24 permit ingrowth of individual blood vessel stems and have a size of approximately 100 to 500 micrometers. They are produced by interfacing of two yarn elements.
  • microscopic openings 34 with a diameter in the range of 5 to 50 micrometers which permit the ingrowth of cells and cell aggregates with capillaries if necessary. These openings 34 are between different filaments.
  • the openings 14 , 24 and 34 form groups of hole patterns.
  • the openings 14 , the openings 24 and the openings 34 are greater or smaller in relation to another group of openings by a factor of approximately at least 5.
  • Within each group the openings can to a certain extent be the same size or can be of different sizes.
  • the distribution can be regular or also random in the sense that a device for embroidering a textile material controls the random distribution of the openings on the whole surface of the textile material with the aid of a random number generator.
  • Reference number 13 denotes an embroidery point which, in the illustrative embodiment shown, lies between two edges of the diamond-shaped openings 14 .
  • This embroidery point 13 is three-dimensional relative to the drawing plane and thus the plane of the embroidered layer 12 and has in particular a section protruding by 3 to 5 mm. In the illustrative embodiment shown, this is almost semispherical, but can also have other three-dimensional structures.
  • this embroidery point can also be three-dimensional on the side pointing toward the knitted spacer, in particular in order to form an abutment.
  • the regular arrangement of the embroidery shown in the figures is not system-related and instead can be changed as desired in accordance with the use on the basis of the embroidery technique.
  • sequences of large and small apertures 14 are possible. As is shown in FIG. 2 , these can have a gradient.
  • the sequence of embroidery points 13 and openings 14 is purely functional and not dictated by the manufacturing technology of the textile fabric.
  • apertures or pores 14 are spanned by a continuous thread 18 according to FIG. 3 , which for example runs from knot to knot in the embroidery of knots 13 .
  • the interplay of the different hole sizes of the openings 14 , 24 , 34 favorably influences the ingrowth of blood vessels, so-called angiogenesis.
  • Main growths have a size of 0.5 to 1 mm here.
  • Monofilaments, multifilaments or mixtures of these can be used in the embroidery process.
  • the strength of the embroidery can be determined through the choice of yarn and the specified pattern.
  • An advantage over a knit is that the thread cannot move in the interfacings, that is to say the mechanical properties of the embroidery are defined by the arrangements of the interfacings and are hardly affected by the incorporation of exudate or extracellular matrix into the thread, which leads to the interfacings sticking together.
  • the mechanical properties are mainly defined by the movability of the thread through the open interfacing.
  • an adhesive exudate leads to an increase in the rigidness of the textile in some circumstances far more than an order of size. This is a considerable disadvantage for the medical product since the mechanical properties which are crucial for its medical functionality can no longer be controlled. Stiffening can cause local loading conditions which can lead to local tissue necrosis.
  • a textile base such as a compress
  • other possible uses can also be envisaged.
  • This can include the use of the embroidered surface material on a metallic or ceramic base or other wound-treating elements.
  • the embroidery technique makes it possible to produce suitable surface elements for each individual case.

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  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
US11/436,184 1999-02-04 2000-01-28 Medicinal product with a textile component Expired - Fee Related USRE40833E1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99810089A EP1025821A1 (de) 1999-02-04 1999-02-04 Medizinalprodukt mit textilem Bestandteil
PCT/CH2000/000041 WO2000045761A1 (de) 1999-02-04 2000-01-28 Medizinalprodukt mit textilem bestandteil

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US09/890,635 Reissue US6737149B1 (en) 1999-02-04 2000-01-28 Medicinal product with a textile component

Publications (1)

Publication Number Publication Date
USRE40833E1 true USRE40833E1 (en) 2009-07-07

Family

ID=8242659

Family Applications (2)

Application Number Title Priority Date Filing Date
US11/436,184 Expired - Fee Related USRE40833E1 (en) 1999-02-04 2000-01-28 Medicinal product with a textile component
US09/890,635 Ceased US6737149B1 (en) 1999-02-04 2000-01-28 Medicinal product with a textile component

Family Applications After (1)

Application Number Title Priority Date Filing Date
US09/890,635 Ceased US6737149B1 (en) 1999-02-04 2000-01-28 Medicinal product with a textile component

Country Status (8)

Country Link
US (2) USRE40833E1 (de)
EP (2) EP1025821A1 (de)
JP (1) JP2002536067A (de)
AT (1) ATE272376T1 (de)
AU (1) AU769188B2 (de)
CA (1) CA2360856A1 (de)
DE (1) DE50007293D1 (de)
WO (1) WO2000045761A1 (de)

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US8317808B2 (en) 2008-02-18 2012-11-27 Covidien Lp Device and method for rolling and inserting a prosthetic patch into a body cavity
US8753359B2 (en) 2008-02-18 2014-06-17 Covidien Lp Device and method for deploying and attaching an implant to a biological tissue
US8758373B2 (en) 2008-02-18 2014-06-24 Covidien Lp Means and method for reversibly connecting a patch to a patch deployment device
US8808314B2 (en) 2008-02-18 2014-08-19 Covidien Lp Device and method for deploying and attaching an implant to a biological tissue
US8888811B2 (en) 2008-10-20 2014-11-18 Covidien Lp Device and method for attaching an implant to biological tissue
US8906045B2 (en) 2009-08-17 2014-12-09 Covidien Lp Articulating patch deployment device and method of use
US9034002B2 (en) 2008-02-18 2015-05-19 Covidien Lp Lock bar spring and clip for implant deployment device
US9044235B2 (en) 2008-02-18 2015-06-02 Covidien Lp Magnetic clip for implant deployment device
US9301826B2 (en) 2008-02-18 2016-04-05 Covidien Lp Lock bar spring and clip for implant deployment device
US9393002B2 (en) 2008-02-18 2016-07-19 Covidien Lp Clip for implant deployment device
US9393093B2 (en) 2008-02-18 2016-07-19 Covidien Lp Clip for implant deployment device
US9398944B2 (en) 2008-02-18 2016-07-26 Covidien Lp Lock bar spring and clip for implant deployment device
US9833240B2 (en) 2008-02-18 2017-12-05 Covidien Lp Lock bar spring and clip for implant deployment device
US9999424B2 (en) 2009-08-17 2018-06-19 Covidien Lp Means and method for reversibly connecting an implant to a deployment device

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US7754937B2 (en) * 2004-03-18 2010-07-13 Boehringer Technologies, L.P. Wound packing material for use with suction
US7884258B2 (en) 2004-04-13 2011-02-08 Boehringer Technologies, L.P. Wound contact device
US7951124B2 (en) * 2004-04-13 2011-05-31 Boehringer Technologies, Lp Growth stimulating wound dressing with improved contact surfaces
JP2010517638A (ja) * 2007-02-02 2010-05-27 トアニエ， インコーポレイテッド 腱および靱帯を修復するシステムおよび方法
GB0809721D0 (en) * 2008-05-28 2008-07-02 Univ Bath Improvements in or relating to joints and/or implants
DE102008044005A1 (de) 2008-11-24 2010-05-27 Leibniz-Institut Für Polymerforschung Dresden E.V. Flächiges Implantat und Verfahren zu seiner Herstellung
EP2391395A4 (de) * 2009-02-02 2014-04-09 Biomerix Corp Verbundnetzvorrichtung und verfahren zur weichgewebereparatur
US9034048B2 (en) * 2011-01-26 2015-05-19 John A. Choren Orthopaedic implants and methods of forming implant structures
GB201120693D0 (en) * 2011-12-01 2012-01-11 Convatec Technologies Inc Wound dressing for use in vacuum therapy
JP6089262B2 (ja) * 2012-03-01 2017-03-08 アルケア株式会社 傷手当用品
DE102012014116B4 (de) * 2012-07-17 2015-05-28 Ulrich Östreicher Abdominalverband
US11224465B2 (en) 2018-12-04 2022-01-18 Spinewelding Ag Surgical methods for the treatment of spinal stenosis

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Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9833240B2 (en) 2008-02-18 2017-12-05 Covidien Lp Lock bar spring and clip for implant deployment device
US9393093B2 (en) 2008-02-18 2016-07-19 Covidien Lp Clip for implant deployment device
US8753359B2 (en) 2008-02-18 2014-06-17 Covidien Lp Device and method for deploying and attaching an implant to a biological tissue
US8758373B2 (en) 2008-02-18 2014-06-24 Covidien Lp Means and method for reversibly connecting a patch to a patch deployment device
US8808314B2 (en) 2008-02-18 2014-08-19 Covidien Lp Device and method for deploying and attaching an implant to a biological tissue
US9034002B2 (en) 2008-02-18 2015-05-19 Covidien Lp Lock bar spring and clip for implant deployment device
US10182898B2 (en) 2008-02-18 2019-01-22 Covidien Lp Clip for implant deployment device
US9107726B2 (en) 2008-02-18 2015-08-18 Covidien Lp Device and method for deploying and attaching an implant to a biological tissue
US10695155B2 (en) 2008-02-18 2020-06-30 Covidien Lp Device and method for deploying and attaching an implant to a biological tissue
US10159554B2 (en) 2008-02-18 2018-12-25 Covidien Lp Clip for implant deployment device
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US9301826B2 (en) 2008-02-18 2016-04-05 Covidien Lp Lock bar spring and clip for implant deployment device
US9393002B2 (en) 2008-02-18 2016-07-19 Covidien Lp Clip for implant deployment device
US9044235B2 (en) 2008-02-18 2015-06-02 Covidien Lp Magnetic clip for implant deployment device
US9398944B2 (en) 2008-02-18 2016-07-26 Covidien Lp Lock bar spring and clip for implant deployment device
US8317808B2 (en) 2008-02-18 2012-11-27 Covidien Lp Device and method for rolling and inserting a prosthetic patch into a body cavity
US8888811B2 (en) 2008-10-20 2014-11-18 Covidien Lp Device and method for attaching an implant to biological tissue
US8734473B2 (en) 2009-02-18 2014-05-27 Covidien Lp Device and method for rolling and inserting a prosthetic patch into a body cavity
US9999424B2 (en) 2009-08-17 2018-06-19 Covidien Lp Means and method for reversibly connecting an implant to a deployment device
US8906045B2 (en) 2009-08-17 2014-12-09 Covidien Lp Articulating patch deployment device and method of use

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EP1025821A1 (de) 2000-08-09
ATE272376T1 (de) 2004-08-15
AU2089100A (en) 2000-08-25
EP1158942B1 (de) 2004-08-04
DE50007293D1 (de) 2004-09-09
EP1158942A1 (de) 2001-12-05
WO2000045761A1 (de) 2000-08-10
AU769188B2 (en) 2004-01-22
CA2360856A1 (en) 2000-08-10
JP2002536067A (ja) 2002-10-29
US6737149B1 (en) 2004-05-18

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