USD900330S1 - Instrument - Google Patents

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Publication number
USD900330S1
USD900330S1 US29/675,465 US201929675465F USD900330S US D900330 S1 USD900330 S1 US D900330S1 US 201929675465 F US201929675465 F US 201929675465F US D900330 S USD900330 S US D900330S
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United States
Prior art keywords
instrument
view
ornamental design
design
perspective
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US29/675,465
Inventor
Jon Faiz Kayyem
Matthew Sean Thomas
Mathieu Dominic Turpault
Christopher John Murray
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Roche Molecular Systems Inc
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Genmark Diagnostics Inc
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Priority to US29/675,465 priority Critical patent/USD900330S1/en
Assigned to GENMARK DIAGNOSTICS, INC. reassignment GENMARK DIAGNOSTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: KAYYEM, JON FAIZ, MURRAY, CHRISTOPHER JOHN, TURPAULT, MATHIEU DOMINIC, THOMAS, MATTHEW SEAN
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Publication of USD900330S1 publication Critical patent/USD900330S1/en
Assigned to ROCHE MOLECULAR SYSTEMS, INC. reassignment ROCHE MOLECULAR SYSTEMS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: GENMARK DIAGNOSTICS, INC.
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6825Nucleic acid detection involving sensors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52Containers specially adapted for storing or dispensing a reagent
    • B01L3/523Containers specially adapted for storing or dispensing a reagent with means for closing or opening
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/025Align devices or objects to ensure defined positions relative to each other
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16Reagents, handling or storing thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/02Identification, exchange or storage of information
    • B01L2300/021Identification, e.g. bar codes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0672Integrated piercing tool
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867Multiple inlets and one sample wells, e.g. mixing, dilution
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0427Electrowetting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0677Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B01L2400/0683Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/52Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip

Description

FIG. 1 is a perspective view of an instrument.
FIG. 2 is a front view of the instrument shown in FIG. 1; and,
FIG. 3 is a right side view of the instrument shown in FIG. 1.
The bottom, top, and rear views are not shown and form no part of the claimed design.
The broken lines illustrate portions of the instrument that form no part of the claimed design.

Claims (1)

    CLAIM
  1. The ornamental design for an instrument, as shown and described.
US29/675,465 2012-10-24 2019-01-02 Instrument Active USD900330S1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US29/675,465 USD900330S1 (en) 2012-10-24 2019-01-02 Instrument

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261717887P 2012-10-24 2012-10-24
US201361798091P 2013-03-15 2013-03-15
US14/062,865 US9957553B2 (en) 2012-10-24 2013-10-24 Integrated multiplex target analysis
US15/901,489 US20180223345A1 (en) 2012-10-24 2018-02-21 Integrated multiplex target analysis
US29/675,465 USD900330S1 (en) 2012-10-24 2019-01-02 Instrument

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US15/901,489 Continuation US20180223345A1 (en) 2012-10-24 2018-02-21 Integrated multiplex target analysis

Publications (1)

Publication Number Publication Date
USD900330S1 true USD900330S1 (en) 2020-10-27

Family

ID=50545285

Family Applications (4)

Application Number Title Priority Date Filing Date
US14/062,865 Active US9957553B2 (en) 2012-10-24 2013-10-24 Integrated multiplex target analysis
US15/901,489 Abandoned US20180223345A1 (en) 2012-10-24 2018-02-21 Integrated multiplex target analysis
US29/675,465 Active USD900330S1 (en) 2012-10-24 2019-01-02 Instrument
US17/144,708 Active 2034-10-26 US11952618B2 (en) 2012-10-24 2021-01-08 Integrated multiplex target analysis

Family Applications Before (2)

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US14/062,865 Active US9957553B2 (en) 2012-10-24 2013-10-24 Integrated multiplex target analysis
US15/901,489 Abandoned US20180223345A1 (en) 2012-10-24 2018-02-21 Integrated multiplex target analysis

Family Applications After (1)

Application Number Title Priority Date Filing Date
US17/144,708 Active 2034-10-26 US11952618B2 (en) 2012-10-24 2021-01-08 Integrated multiplex target analysis

Country Status (6)

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US (4) US9957553B2 (en)
EP (4) EP3427830B1 (en)
JP (5) JP1628115S (en)
AU (3) AU2013334189B2 (en)
CA (1) CA2889415C (en)
WO (1) WO2014066704A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD981570S1 (en) * 2021-10-25 2023-03-21 Dongguan Hongyu Plastic Co., Ltd. Spa apparatus

Families Citing this family (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201014805D0 (en) 2010-09-07 2010-10-20 Multi Sense Technologies Ltd Microfluidics based assay device
WO2013113072A1 (en) 2012-02-03 2013-08-08 Axxin Pty Ltd Nucleic acid amplification and detection apparatus and method
WO2014066704A1 (en) 2012-10-24 2014-05-01 Genmark Diagnostics, Inc. Integrated multiplex target analysis
US20140322706A1 (en) 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
US10610861B2 (en) 2012-12-17 2020-04-07 Accellix Ltd. Systems, compositions and methods for detecting a biological condition
EP3508848B1 (en) 2012-12-17 2022-10-05 Accellix Ltd Systems and methods for determining a chemical state
US20140170678A1 (en) * 2012-12-17 2014-06-19 Leukodx Ltd. Kits, compositions and methods for detecting a biological condition
EP2951593B1 (en) 2013-01-31 2018-09-19 Luminex Corporation Fluid retention plates and analysis cartridges
WO2014138563A1 (en) * 2013-03-07 2014-09-12 Quidel Corporation Dual chamber liquid packaging system
US10545161B2 (en) 2013-03-11 2020-01-28 Cue Health Inc. Systems and methods for detection and quantification of analytes
US9623409B2 (en) 2013-03-11 2017-04-18 Cue Inc. Cartridges, kits, and methods for enhanced mixing for detection and quantification of analytes
KR101613104B1 (en) 2013-03-11 2016-04-18 큐 인코퍼레이티드 Systems and methods for detection and quantification of analytes
WO2017015172A1 (en) 2015-07-17 2017-01-26 Cue Inc. Systems and methods for enhanced detection and quantification of analytes
JP6351702B2 (en) 2013-03-15 2018-07-04 ジェンマーク ダイアグノスティクス, インコーポレイテッド System, method and apparatus for operating a deformable fluid container
GB2516667A (en) * 2013-07-29 2015-02-04 Atlas Genetics Ltd An improved cartridge, cartridge reader and method for preventing reuse
US9498778B2 (en) 2014-11-11 2016-11-22 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
USD881409S1 (en) 2013-10-24 2020-04-14 Genmark Diagnostics, Inc. Biochip cartridge
JP2015104363A (en) * 2013-11-29 2015-06-08 セイコーエプソン株式会社 Cartridge for nucleic acid amplification reaction and cartridge kit for nucleic acid amplification reaction
CN105960282A (en) * 2014-01-07 2016-09-21 达克雷诊断器材有限公司 Fluid delivery devices, systems, and methods
WO2015105797A1 (en) * 2014-01-07 2015-07-16 Daktari Diagnostics, Inc. Fluid delivery devices, systems, and methods
US10828636B2 (en) * 2016-10-25 2020-11-10 Fannin Partners Llc Automated remotely instructed driving of an assay
USD745423S1 (en) 2014-05-12 2015-12-15 Cue Inc. Automated analyzer test cartridge and sample collection device for analyte detection
WO2015178929A1 (en) * 2014-05-23 2015-11-26 Laird Durham, Inc. Thermoelectric heating/cooling devices including resistive heaters
WO2015195831A1 (en) 2014-06-17 2015-12-23 Life Technologies Corporation Sequencing device
EP3191849A1 (en) * 2014-09-11 2017-07-19 Cue Inc. Systems and methods for detection and quantification of analytes
US9694360B2 (en) * 2014-09-29 2017-07-04 Bio-Rad Laboratories, Inc. Fluid manipulator having flexible blister
US10196678B2 (en) 2014-10-06 2019-02-05 ALVEO Technologies Inc. System and method for detection of nucleic acids
EP3218108B1 (en) 2014-11-11 2020-09-02 Genmark Diagnostics Inc. Fluid sample processing cartridge and use thereof
US10005080B2 (en) * 2014-11-11 2018-06-26 Genmark Diagnostics, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation
US9500663B2 (en) * 2014-11-11 2016-11-22 Genmark Diagnostics, Inc. Redundant identification for sample tracking on a diagnostic device
US9598722B2 (en) 2014-11-11 2017-03-21 Genmark Diagnostics, Inc. Cartridge for performing assays in a closed sample preparation and reaction system
FR3028318A1 (en) * 2014-11-12 2016-05-13 Phuong Lan Tran METHOD AND DEVICE FOR SELECTIVE, SPECIFIC AND SIMULTANEOUS SORTING OF TARGET RARE CELLS IN A BIOLOGICAL SAMPLE
WO2016074046A1 (en) 2014-11-14 2016-05-19 Axxin Pty Ltd Biological sample collection and storage assembly
US9885352B2 (en) 2014-11-25 2018-02-06 Genia Technologies, Inc. Selectable valve of a delivery system
DE102015205906A1 (en) * 2015-04-01 2016-10-20 Robert Bosch Gmbh Storage unit, method for producing a storage unit and method for releasing a stored in a storage unit fluid
JP7079092B2 (en) 2015-04-03 2022-06-01 アボット・ラボラトリーズ Devices and methods for sample analysis
CA2981512A1 (en) 2015-04-03 2016-10-06 Abbott Laboratories Devices and methods for sample analysis
USD771834S1 (en) * 2015-04-28 2016-11-15 University Of British Columbia Microfluidic cartridge
EP3303548A4 (en) 2015-06-05 2019-01-02 Miroculus Inc. Evaporation management in digital microfluidic devices
WO2016197103A1 (en) 2015-06-05 2016-12-08 Miroculus Inc. Air-matrix digital microfluidics apparatuses and methods for limiting evaporation and surface fouling
CN108139387B (en) * 2015-06-29 2020-12-11 源鉴定私人有限公司 Method and apparatus for collecting test data from use of disposable test kits
WO2017004463A1 (en) 2015-07-01 2017-01-05 Abbott Laboratories Devices and methods for sample analysis
FR3038383B1 (en) * 2015-07-03 2017-07-07 Avalun APPARATUS FOR ANALYZING A LIQUID SAMPLE COMPRISING A BLOCKING AND EJECTING DEVICE
AU2016295422B2 (en) * 2015-07-17 2022-01-06 Axxin Pty Ltd Diagnostic test assembly, apparatus, method
ES2891524T3 (en) * 2015-07-24 2022-01-28 Novel Microdevices Inc Sample processing device comprising magnetic and mechanical drive elements using linear or rotational motion
WO2017048815A1 (en) * 2015-09-14 2017-03-23 Singulex, Inc. Single molecule detection on a chip
CN105861646A (en) * 2016-03-02 2016-08-17 成都市妇女儿童中心医院 Electrochemical biological chip for detecting urinary tract pathogen 16SrRNA and technical application thereof
WO2017190139A1 (en) * 2016-04-29 2017-11-02 Baebies, Inc. Point-of-birth system and instrument, biochemical cartridge, and methods for newborn screening
GB201611442D0 (en) * 2016-06-30 2016-08-17 Lumiradx Tech Ltd Fluid control
SG11201900756QA (en) * 2016-07-28 2019-02-27 Biofire Diagnostics Llc Self-contained nucleic acid processing
EP3500660A4 (en) 2016-08-22 2020-03-04 Miroculus Inc. Feedback system for parallel droplet control in a digital microfluidic device
JP2019528678A (en) * 2016-09-15 2019-10-17 アボット・ラボラトリーズAbbott Laboratories Apparatus and method for sample analysis
EP3516401A1 (en) 2016-09-19 2019-07-31 Genmark Diagnostics Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
JP7146743B2 (en) 2016-09-23 2022-10-04 アルヴェオ テクノロジーズ インコーポレイテッド Methods and compositions for detecting analytes
CN109863396B (en) * 2016-10-05 2021-11-05 雅培实验室 Device and method for sample analysis
US11016053B2 (en) 2016-10-05 2021-05-25 Abbott Laboratories Devices and methods for sample analysis
EP3523041A1 (en) * 2016-10-07 2019-08-14 Boehringer Ingelheim Vetmedica GmbH Cartridge and analysis system for testing a sample
CN109789412B (en) * 2016-10-07 2022-07-08 勃林格殷格翰维特梅迪卡有限公司 Analysis system and method for detecting sample
CN110226089B (en) * 2016-12-01 2022-11-01 新型微装置有限责任公司 Automated field test device for complex sample processing and method of use thereof
CN110383061A (en) 2016-12-28 2019-10-25 米罗库鲁斯公司 Digital microcurrent-controlled device and method
WO2018140540A1 (en) 2017-01-25 2018-08-02 Cue Health Inc. Systems and methods for enhanced detection and quantification of analytes
WO2018144018A1 (en) * 2017-02-03 2018-08-09 Hewlett-Packard Development Company, L.P. Cassettes with offset vias
WO2018187476A1 (en) 2017-04-04 2018-10-11 Miroculus Inc. Digital microfluidic apparatuses and methods for manipulating and processing encapsulated droplets
TWI799381B (en) * 2017-07-10 2023-04-21 英商盧米瑞德克斯英國有限公司 A self-contained microfluidic system, as well as an assay system, kit or methods employing the self-contained microfluidic system
WO2019023133A1 (en) 2017-07-24 2019-01-31 Miroculus Inc. Digital microfluidics systems and methods with integrated plasma collection device
US20190062809A1 (en) 2017-08-24 2019-02-28 Clinical Micro Sensors, Inc. (dba GenMark Diagnostics, Inc.) Electrochemical detection of bacterial and/or fungal infections
WO2019040769A1 (en) 2017-08-24 2019-02-28 Clinical Micro Sensors, Inc. (dba GenMark Diagnostics, Inc.) Electrochemical detection of bacterial and/or fungal infections
WO2019045807A1 (en) * 2017-08-31 2019-03-07 Biofire Defense, Llc. Assay devices and methods of use thereof
CN115582155A (en) 2017-09-01 2023-01-10 米罗库鲁斯公司 Digital microfluidic device and method of use thereof
AU2018340855B2 (en) 2017-09-27 2023-06-22 Axxin Pty Ltd Diagnostic test system and method
EP3470141A1 (en) * 2017-10-11 2019-04-17 F. Hoffmann-La Roche AG Method for processing a biological sample with magnetic particles
GR1009763B (en) * 2018-03-13 2020-06-12 Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων (Εκεφε) " Δημοκριτος" An integrated pcb-based microdevice for sensitive nucleic acid detection, and method for its production
JP7052010B2 (en) * 2018-03-31 2022-04-11 アジアメディカルセンター,プライベート リミテッド Biological sample processing tool, pressing system and biological sample processing method
EP3788371A1 (en) 2018-05-04 2021-03-10 Abbott Laboratories Sequential sampling method for improving immunoassay sensitivity and kinetics of small volume samples
US10527528B2 (en) * 2018-05-22 2020-01-07 Applikate Technologies Llc Tissue chamber
WO2019230566A1 (en) * 2018-05-31 2019-12-05 キヤノン株式会社 Analysis system
US10935561B2 (en) 2018-06-01 2021-03-02 Genmark Diagnostics, Inc. Integrated diagnostic instrument
US10948450B2 (en) 2018-07-23 2021-03-16 Genmark Diagnostics, Inc. Electrochemical measurements of components in coatings
US20210178392A1 (en) 2018-08-27 2021-06-17 Novel Microdevices, Llc Sample-to-answer microfluidic system and method including vertical microfluidic device and automated actuation mechanisms
US10352983B1 (en) 2018-10-04 2019-07-16 Genmark Diagnostics, Inc. Systems and methods for assessing electrical connectivity between elements of assay devices
US10753986B2 (en) 2018-10-04 2020-08-25 Genmark Diagnostics, Inc. Systems and methods for assessing electrical connectivity between elements of assay devices
EP3887814A4 (en) * 2018-12-02 2022-08-24 Polymer Technology Systems, Inc. Systems and methods for an e-gating feature in an electrochemical test strip
US20200174025A1 (en) * 2018-12-02 2020-06-04 Polymer Technology Systems, Inc. Systems and methods for a combined strip detection and heating system in an electrochemical test strip
KR102204934B1 (en) * 2018-12-06 2021-01-21 한국전자기술연구원 PCB Based Bio-Chip
EP3903103A1 (en) 2018-12-28 2021-11-03 Abbott Laboratories Direct detection of single molecules on microparticles
US20210220828A1 (en) * 2019-01-15 2021-07-22 Beijing Boe Optoelectronics Technology Co., Ltd. Biological detection substrate, microfluidic chip and driving method thereof, microfluidic detection component
USD940860S1 (en) * 2019-03-15 2022-01-11 Chiesi Farmaceutici S.P.A. Administration kit and associated components thereof
CA3133124A1 (en) 2019-04-08 2020-10-15 Miroculus Inc. Multi-cartridge digital microfluidics apparatuses and methods of use
CN112114013B (en) * 2019-06-19 2023-04-14 国竤工业有限公司 Multi-channel biochemical detection test piece
EP3756762A1 (en) * 2019-06-25 2020-12-30 Sharp Life Science (EU) Limited Microfluidic device and a method of manipulating droplets therein
EP3756761A1 (en) * 2019-06-25 2020-12-30 Sharp Life Science (EU) Limited Microfluidic device and a method of manipulating droplets therein
WO2021016614A1 (en) 2019-07-25 2021-01-28 Miroculus Inc. Digital microfluidics devices and methods of use thereof
JP2022543618A (en) 2019-08-07 2022-10-13 アボット・ラボラトリーズ Chemiluminescent compounds for multiplexing
EP4010707A1 (en) 2019-08-07 2022-06-15 Abbott Laboratories Methods for detecting assay interferents and increasing dynamic range
EP3812042A1 (en) 2019-10-25 2021-04-28 Sharp Life Science (EU) Limited Ewod device with sensing apparatus
EP3812041A1 (en) 2019-10-25 2021-04-28 Sharp Life Science (EU) Limited Method of operating ewod device with sensing apparatus
USD949432S1 (en) 2019-11-25 2022-04-19 Illumina, Inc. Reagent cartridge
US11524297B2 (en) 2019-12-03 2022-12-13 Sharp Life Science (Eu) Limited Method of concentrating particles in a liquid droplet using an EWOD device with sensing apparatus
TWI742905B (en) * 2019-12-10 2021-10-11 財團法人工業技術研究院 Nucleic acid extracting device
CN112940061A (en) 2019-12-10 2021-06-11 财团法人工业技术研究院 Nucleic acid extraction device
CN115151346A (en) * 2020-01-24 2022-10-04 科锐丽亚生物系统公司 Automated analyte determination system and kit for use therewith
GB202004720D0 (en) * 2020-03-31 2020-05-13 Osler Diagnostics Ltd Actuator
WO2022035995A2 (en) * 2020-08-14 2022-02-17 Alveo Technologies, Inc. Systems and methods of sample depositing and testing
WO2022104365A1 (en) 2020-11-16 2022-05-19 Siemens Healthcare Diagnostics Inc. Valve for microfluidic device
US20240100523A1 (en) * 2021-02-02 2024-03-28 Nicoya Lifesciences, Inc. Digital microfluidics cartridge, system, and method
WO2022172223A1 (en) * 2021-02-12 2022-08-18 Creganna Unlimited Company Diagnostic assay and therapeutic fluid delivery blister actuator and diagnostic assay and therapeutic fluid delivery cartridge therewith
US11891671B1 (en) * 2021-03-24 2024-02-06 A9.Com, Inc. Virus detection system
GB202104784D0 (en) * 2021-04-01 2021-05-19 Osler Diagnostics Ltd Liquid handling apparatus
US20230043483A1 (en) * 2021-07-09 2023-02-09 Cepheld High-level multiplexing reaction vessel, reagent spotting device and associated methods
US11857961B2 (en) 2022-01-12 2024-01-02 Miroculus Inc. Sequencing by synthesis using mechanical compression
WO2023158574A1 (en) * 2022-02-15 2023-08-24 Strike Photonics, Inc An integrated docking station for fluid analysis of an optical signal received from a photonic chip assembly

Citations (472)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641909A (en) 1969-07-03 1972-02-15 Polaroid Corp System for rupturing a pod containing processing fluid for photographic apparatus
US3687051A (en) 1969-07-03 1972-08-29 Polaroid Corp System for rupturing pod containing processing fluid for photographic material
US3776425A (en) 1969-07-03 1973-12-04 Polaroid Corp System for rupturing pod containing processing fluid for photographic material
US3820149A (en) 1969-07-03 1974-06-25 Polaroid Corp System for rupturing pod containing processing fluid for photographic material
US4007010A (en) 1974-07-03 1977-02-08 Woodbridge Iii Richard G Blister plane apparatus for testing samples of fluid
US4065263A (en) 1976-04-02 1977-12-27 Woodbridge Iii Richard G Analytical test strip apparatus
USD253126S (en) 1977-04-18 1979-10-09 American Home Products Corp. Necropsy board for small animals
US4182447A (en) 1977-07-27 1980-01-08 Ira Kay Device for storing, transporting and mixing reactive ingredients
USD268130S (en) 1980-06-27 1983-03-01 Easton Harlan J Tray for veterinary supplies and equipment
US4429792A (en) 1981-09-11 1984-02-07 Medication Services, Inc. Medication-dispensing card
US4469863A (en) 1980-11-12 1984-09-04 Ts O Paul O P Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
US4526320A (en) 1982-05-15 1985-07-02 Globol-Werk Gmbh Apparatus for vaporizing insecticides, perfumes and/or other volatile agents
USD287760S (en) 1984-03-05 1987-01-13 Discko Jr John J Dental tray
US4739903A (en) 1986-10-01 1988-04-26 Fibre Glass-Evercoat Company, Inc. Dispensing case assembly
US4769333A (en) 1987-01-05 1988-09-06 Dole Associates, Inc. Personal diagnostic kit
US4844251A (en) 1986-08-12 1989-07-04 L'oreal Container means for separately storing at least two products to be brought into contact at the time of use
US4859603A (en) 1987-01-05 1989-08-22 Dole Associates, Inc. Personal diagnostic kit
US4887455A (en) 1987-04-06 1989-12-19 Cogent Limited Gas sensor
US4978502A (en) 1987-01-05 1990-12-18 Dole Associates, Inc. Immunoassay or diagnostic device and method of manufacture
US5034506A (en) 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US5089233A (en) 1989-06-12 1992-02-18 Eastman Kodak Company Processing apparatus for a chemical reaction pack
US5098660A (en) 1990-01-08 1992-03-24 Eastman Kodak Company Transfer apparatus for chemical reaction pack
USD327363S (en) 1988-09-19 1992-06-30 Farb M Daniel Portable ophthalmic instrument case
US5154888A (en) 1990-10-25 1992-10-13 Eastman Kodak Company Automatic sealing closure means for closing off a passage in a flexible cuvette
US5216141A (en) 1988-06-06 1993-06-01 Benner Steven A Oligonucleotide analogs containing sulfur linkages
US5229297A (en) 1989-02-03 1993-07-20 Eastman Kodak Company Containment cuvette for PCR and method of use
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
US5235033A (en) 1985-03-15 1993-08-10 Anti-Gene Development Group Alpha-morpholino ribonucleoside derivatives and polymers thereof
US5254479A (en) 1991-12-19 1993-10-19 Eastman Kodak Company Methods for preventing air injection into a detection chamber supplied with injected liquid
US5288463A (en) 1992-10-23 1994-02-22 Eastman Kodak Company Positive flow control in an unvented container
EP0583833A2 (en) 1992-08-17 1994-02-23 Eastman Kodak Company Flexible extraction device
USD350478S (en) 1993-03-30 1994-09-13 Fuller Kathryn O Weekly pill organizer calendar
USD351996S (en) 1992-06-23 1994-11-01 Multi-Comp, Inc. Dispensing container for pharmaceutical medication
US5374395A (en) 1993-10-14 1994-12-20 Amoco Corporation Diagnostics instrument
US5386023A (en) 1990-07-27 1995-01-31 Isis Pharmaceuticals Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
US5399486A (en) 1993-02-18 1995-03-21 Biocircuits Corporation Disposable unit in diagnostic assays
US5422271A (en) 1992-11-20 1995-06-06 Eastman Kodak Company Nucleic acid material amplification and detection without washing
US5449096A (en) 1993-04-10 1995-09-12 Hilti Aktiengesellschaft Piston for a dispensing tool
US5460780A (en) 1989-06-12 1995-10-24 Devaney, Jr.; Mark J. Temperature control device and reaction vessel
US5468366A (en) 1992-01-15 1995-11-21 Andcare, Inc. Colloidal-gold electrosensor measuring device
US5512439A (en) 1988-11-21 1996-04-30 Dynal As Oligonucleotide-linked magnetic particles and uses thereof
US5529188A (en) 1994-09-28 1996-06-25 Becton Dickinson And Company Child resistant carded type blister folder
US5591578A (en) 1993-12-10 1997-01-07 California Institute Of Technology Nucleic acid mediated electron transfer
US5593804A (en) 1995-12-05 1997-01-14 Eastman Kodak Company Test pouch
US5602240A (en) 1990-07-27 1997-02-11 Ciba Geigy Ag. Backbone modified oligonucleotide analogs
US5637684A (en) 1994-02-23 1997-06-10 Isis Pharmaceuticals, Inc. Phosphoramidate and phosphorothioamidate oligomeric compounds
US5644048A (en) 1992-01-10 1997-07-01 Isis Pharmaceuticals, Inc. Process for preparing phosphorothioate oligonucleotides
US5652149A (en) 1992-12-08 1997-07-29 Westinghouse Electric Corporation Mixing apparatus & method for an optical agglutination assay device
US5681702A (en) 1994-08-30 1997-10-28 Chiron Corporation Reduction of nonspecific hybridization by using novel base-pairing schemes
US5692644A (en) 1994-07-25 1997-12-02 L'oreal Container for storing at least two products, mixing these products, and dispensing the mixture thus obtained
US5705628A (en) 1994-09-20 1998-01-06 Whitehead Institute For Biomedical Research DNA purification and isolation using magnetic particles
US5714380A (en) 1986-10-23 1998-02-03 Amoco Corporation Closed vessel for isolating target molecules and for performing amplification
US5716852A (en) 1996-03-29 1998-02-10 University Of Washington Microfabricated diffusion-based chemical sensor
US5726404A (en) 1996-05-31 1998-03-10 University Of Washington Valveless liquid microswitch
US5726751A (en) 1995-09-27 1998-03-10 University Of Washington Silicon microchannel optical flow cytometer
US5747349A (en) 1996-03-20 1998-05-05 University Of Washington Fluorescent reporter beads for fluid analysis
US5748827A (en) 1996-10-23 1998-05-05 University Of Washington Two-stage kinematic mount
US5770365A (en) 1995-08-25 1998-06-23 Tm Technologies, Inc. Nucleic acid capture moieties
US5807701A (en) 1994-06-09 1998-09-15 Aromascan Plc Method and apparatus for detecting microorganisms
US5820826A (en) 1992-09-03 1998-10-13 Boehringer Mannheim Company Casing means for analytical test apparatus
EP0870541A2 (en) 1997-04-11 1998-10-14 Eastman Kodak Company Integrated ceramic micro-chemical plant
US5824473A (en) 1993-12-10 1998-10-20 California Institute Of Technology Nucleic acid mediated electron transfer
US5842787A (en) 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
US5849486A (en) 1993-11-01 1998-12-15 Nanogen, Inc. Methods for hybridization analysis utilizing electrically controlled hybridization
US5851536A (en) 1995-11-22 1998-12-22 University Of Washington Therapeutic delivery using compounds self-assembled into high axial ratio microstructures
US5873990A (en) 1995-08-22 1999-02-23 Andcare, Inc. Handheld electromonitor device
US5876187A (en) 1995-03-09 1999-03-02 University Of Washington Micropumps with fixed valves
US5882497A (en) 1994-06-23 1999-03-16 Aromascan Plc Semiconducting organic polymers for gas sensors
US5932100A (en) 1995-06-16 1999-08-03 University Of Washington Microfabricated differential extraction device and method
US5948684A (en) 1997-03-31 1999-09-07 University Of Washington Simultaneous analyte determination and reference balancing in reference T-sensor devices
US5955028A (en) 1996-08-02 1999-09-21 Caliper Technologies Corp. Analytical system and method
US5973138A (en) 1998-10-30 1999-10-26 Becton Dickinson And Company Method for purification and manipulation of nucleic acids using paramagnetic particles
US5971158A (en) 1996-06-14 1999-10-26 University Of Washington Absorption-enhanced differential extraction device
US5974867A (en) 1997-06-13 1999-11-02 University Of Washington Method for determining concentration of a laminar sample stream
US6003728A (en) 1998-10-22 1999-12-21 Aptargroup, Inc. Dispensing structure with an openable member for separating two products
US6007775A (en) 1997-09-26 1999-12-28 University Of Washington Multiple analyte diffusion based chemical sensor
US6013459A (en) 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
US6033601A (en) 1994-12-14 2000-03-07 Aromascan Plc Semiconducting organic polymers
US6039897A (en) 1996-08-28 2000-03-21 University Of Washington Multiple patterned structures on a single substrate fabricated by elastomeric micro-molding techniques
US6063573A (en) 1998-01-27 2000-05-16 Clinical Micro Sensors, Inc. Cycling probe technology using electron transfer detection
US6067157A (en) 1998-10-09 2000-05-23 University Of Washington Dual large angle light scattering detection
US6065641A (en) 1997-07-16 2000-05-23 Laboratorios Inibsa, S.A. Cartridge containing two liquids
US6091502A (en) 1998-12-23 2000-07-18 Micronics, Inc. Device and method for performing spectral measurements in flow cells with spatial resolution
US6090933A (en) 1996-11-05 2000-07-18 Clinical Micro Sensors, Inc. Methods of attaching conductive oligomers to electrodes
US6096273A (en) 1996-11-05 2000-08-01 Clinical Micro Sensors Electrodes linked via conductive oligomers to nucleic acids
US6098795A (en) 1997-10-14 2000-08-08 Mollstam; Bo Device for adding a component to a package
US6110354A (en) 1996-11-01 2000-08-29 University Of Washington Microband electrode arrays
US6123798A (en) 1998-05-06 2000-09-26 Caliper Technologies Corp. Methods of fabricating polymeric structures incorporating microscale fluidic elements
US6136272A (en) 1997-09-26 2000-10-24 University Of Washington Device for rapidly joining and splitting fluid layers
US6159739A (en) 1997-03-26 2000-12-12 University Of Washington Device and method for 3-dimensional alignment of particles in microfabricated flow channels
US6167910B1 (en) 1998-01-20 2001-01-02 Caliper Technologies Corp. Multi-layer microfluidic devices
US6180064B1 (en) 1994-06-23 2001-01-30 Osmetech Plc Semiconducting organic polymer gas sensor
US6180114B1 (en) 1996-11-21 2001-01-30 University Of Washington Therapeutic delivery using compounds self-assembled into high axial ratio microstructures
US6190858B1 (en) 1997-01-02 2001-02-20 Osmetech Plc Detection of conditions by analysis of gases or vapors
US6192351B1 (en) 1995-02-24 2001-02-20 Osmetech Plc Fuzzy neural networks
US6221677B1 (en) 1997-09-26 2001-04-24 University Of Washington Simultaneous particle separation and chemical reaction
US6227809B1 (en) 1995-03-09 2001-05-08 University Of Washington Method for making micropumps
US6232062B1 (en) 1997-03-07 2001-05-15 Clinical Micro Sensors, Inc. AC methods for the detection of nucleic acids
US6230884B1 (en) 1997-03-12 2001-05-15 Fredrick Michael Coory Discharge cap with releasable tablet basket
US6236951B1 (en) 1995-11-16 2001-05-22 Osmetech Plc Sensor interrogation
US6235501B1 (en) 1995-02-14 2001-05-22 Bio101, Inc. Method for isolation DNA
US6255477B1 (en) 1995-06-08 2001-07-03 Roche Diagnostics Gmbh Particles having a magnetic core and outer glass layer for separating biological material
US6264825B1 (en) 1998-06-23 2001-07-24 Clinical Micro Sensors, Inc. Binding acceleration techniques for the detection of analytes
US6268136B1 (en) 1997-06-16 2001-07-31 Exact Science Corporation Methods for stool sample preparation
US6300138B1 (en) 1997-08-01 2001-10-09 Qualigen, Inc. Methods for conducting tests
US20020006643A1 (en) 1998-01-27 2002-01-17 Jon Faiz Kayyem Amplification of nucleic acids with electronic detection
US6361958B1 (en) 1999-11-12 2002-03-26 Motorola, Inc. Biochannel assay for hybridization with biomaterial
US6366924B1 (en) 1998-07-27 2002-04-02 Caliper Technologies Corp. Distributed database for analytical instruments
US6376232B1 (en) 1997-03-06 2002-04-23 Osmetech Plc Microorganism analysis means
US6387290B1 (en) 1995-06-16 2002-05-14 University Of Washington Tangential flow planar microfabricated fluid filter
US6391558B1 (en) 1997-03-18 2002-05-21 Andcare, Inc. Electrochemical detection of nucleic acid sequences
US6391622B1 (en) 1997-04-04 2002-05-21 Caliper Technologies Corp. Closed-loop biochemical analyzers
US20020066677A1 (en) 2000-12-01 2002-06-06 Brett Moscovitz Device for storing and dispensing a substance by mating with a container and associated methods
US20020068357A1 (en) 1995-09-28 2002-06-06 Mathies Richard A. Miniaturized integrated nucleic acid processing and analysis device and method
US6403338B1 (en) 1997-04-04 2002-06-11 Mountain View Microfluidic systems and methods of genotyping
US6406857B1 (en) 1997-06-16 2002-06-18 Exact Sciences Corporation Methods for stool sample preparation
US6408884B1 (en) 1999-12-15 2002-06-25 University Of Washington Magnetically actuated fluid handling devices for microfluidic applications
US6409832B2 (en) 2000-03-31 2002-06-25 Micronics, Inc. Protein crystallization in microfluidic structures
US6426230B1 (en) 1997-08-01 2002-07-30 Qualigen, Inc. Disposable diagnostic device and method
US6431212B1 (en) 2000-05-24 2002-08-13 Jon W. Hayenga Valve for use in microfluidic structures
US6431016B1 (en) 1997-07-05 2002-08-13 Osmetech Plc Apparatus and methods for gas sampling
US6432723B1 (en) 1999-01-22 2002-08-13 Clinical Micro Sensors, Inc. Biosensors utilizing ligand induced conformation changes
US6431476B1 (en) 1999-12-21 2002-08-13 Cepheid Apparatus and method for rapid ultrasonic disruption of cells or viruses
US6440725B1 (en) 1997-12-24 2002-08-27 Cepheid Integrated fluid manipulation cartridge
US6443307B1 (en) 2000-01-25 2002-09-03 Michael D. Burridge Medication dispenser with an internal ejector
US6443179B1 (en) 2001-02-21 2002-09-03 Sandia Corporation Packaging of electro-microfluidic devices
US6451606B1 (en) 1999-01-30 2002-09-17 Fresenius Medical Care Deutschland Gmbh Receptacle unit for solutions, in particular solutions for calibration of sensors for measuring physiologically relevant parameters
US6454945B1 (en) 1995-06-16 2002-09-24 University Of Washington Microfabricated devices and methods
US6482306B1 (en) 1998-09-22 2002-11-19 University Of Washington Meso- and microfluidic continuous flow and stopped flow electroösmotic mixer
US6488896B2 (en) 2000-03-14 2002-12-03 Micronics, Inc. Microfluidic analysis cartridge
US6488895B1 (en) 1998-10-29 2002-12-03 Caliper Technologies Corp. Multiplexed microfluidic devices, systems, and methods
US6495104B1 (en) 1999-08-19 2002-12-17 Caliper Technologies Corp. Indicator components for microfluidic systems
US20030025129A1 (en) 2001-07-24 2003-02-06 Lg.Electronics Inc. Handling and delivering fluid through a microchannel in an elastic substrate by progressively squeezing the microchannel along its length
US6518024B2 (en) 1999-12-13 2003-02-11 Motorola, Inc. Electrochemical detection of single base extension
US20030034271A1 (en) 2000-01-25 2003-02-20 Burridge Michael D. Internal ejector punch for blister-pack type containers
US6524456B1 (en) 1999-08-12 2003-02-25 Ut-Battelle, Llc Microfluidic devices for the controlled manipulation of small volumes
US20030038040A1 (en) 2000-03-01 2003-02-27 Mathias Bertl Device for storing and dispensing a free-flowing substance
US20030048631A1 (en) 2000-03-01 2003-03-13 Jacques Ladyjensky Chemiluminescent lighting element
US6537501B1 (en) 1998-05-18 2003-03-25 University Of Washington Disposable hematology cartridge
US6541213B1 (en) 1996-03-29 2003-04-01 University Of Washington Microscale diffusion immunoassay
US6541617B1 (en) 1998-10-27 2003-04-01 Clinical Micro Sensors, Inc. Detection of target analytes using particles and electrodes
US6557427B2 (en) 2000-05-24 2003-05-06 Micronics, Inc. Capillaries for fluid movement within microfluidic channels
US6562568B1 (en) 1997-10-01 2003-05-13 Roche Diagnostics Gmbh Method, kit and apparatus comprising magnetic glass particles for the isolation of biomolecules
US6565727B1 (en) 1999-01-25 2003-05-20 Nanolytics, Inc. Actuators for microfluidics without moving parts
US6575188B2 (en) 2001-07-26 2003-06-10 Handylab, Inc. Methods and systems for fluid control in microfluidic devices
US6581899B2 (en) 2000-06-23 2003-06-24 Micronics, Inc. Valve for use in microfluidic structures
US6591852B1 (en) 1998-10-13 2003-07-15 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
US6596483B1 (en) 1999-11-12 2003-07-22 Motorola, Inc. System and method for detecting molecules using an active pixel sensor
US6600026B1 (en) 1998-05-06 2003-07-29 Clinical Micro Sensors, Inc. Electronic methods for the detection of analytes utilizing monolayers
US6602400B1 (en) 2000-06-15 2003-08-05 Motorola, Inc. Method for enhanced bio-conjugation events
US6627412B1 (en) 1998-08-21 2003-09-30 Osmetech Plc Method for detecting microorganisms
US6642046B1 (en) 1999-12-09 2003-11-04 Motorola, Inc. Method and apparatus for performing biological reactions on a substrate surface
US6645758B1 (en) 1989-02-03 2003-11-11 Johnson & Johnson Clinical Diagnostics, Inc. Containment cuvette for PCR and method of use
US6655010B1 (en) 1998-03-20 2003-12-02 Osmetech Plc Method for batch manufacturing sensor units
US6660480B2 (en) 1997-04-28 2003-12-09 Ut-Battelle, Llc Method for analyzing nucleic acids by means of a substrate having a microchannel structure containing immobilized nucleic acid probes
US6664104B2 (en) 1999-06-25 2003-12-16 Cepheid Device incorporating a microfluidic chip for separating analyte from a sample
US6674525B2 (en) 2001-04-03 2004-01-06 Micronics, Inc. Split focusing cytometer
US6686150B1 (en) 1998-01-27 2004-02-03 Clinical Micro Sensors, Inc. Amplification of nucleic acids with electronic detection
US20040037739A1 (en) 2001-03-09 2004-02-26 Mcneely Michael Method and system for microfluidic interfacing to arrays
US20040053290A1 (en) 2000-01-11 2004-03-18 Terbrueggen Robert Henry Devices and methods for biochip multiplexing
WO2004034028A2 (en) 2002-10-09 2004-04-22 The Board Of Trustees Of The University Of Illinois Microfluidic systems and components
US6740518B1 (en) 1998-09-17 2004-05-25 Clinical Micro Sensors, Inc. Signal detection techniques for the detection of analytes
US6739531B2 (en) 2001-10-04 2004-05-25 Cepheid Apparatus and method for rapid disruption of cells or viruses
US6743399B1 (en) 1999-10-08 2004-06-01 Micronics, Inc. Pumpless microfluidics
US6742661B1 (en) 2001-04-03 2004-06-01 Micronics, Inc. Well-plate microfluidics
US6753143B2 (en) 2000-05-01 2004-06-22 Clinical Micro Sensors, Inc. Target analyte detection using asymmetrical self-assembled monolayers
US6761816B1 (en) 1998-06-23 2004-07-13 Clinical Micro Systems, Inc. Printed circuit boards with monolayers and capture ligands
US20040137607A1 (en) 2003-01-09 2004-07-15 Yokogawa Electric Corporation Biochip cartridge
US6773566B2 (en) 2000-08-31 2004-08-10 Nanolytics, Inc. Electrostatic actuators for microfluidics and methods for using same
US6783647B2 (en) 2001-10-19 2004-08-31 Ut-Battelle, Llc Microfluidic systems and methods of transport and lysis of cells and analysis of cell lysate
US20040185551A1 (en) 2003-03-20 2004-09-23 Northeastern Ohio Universities College Of Medicine Self-contained assay device for rapid detection of biohazardous agents
US20040189311A1 (en) 2002-12-26 2004-09-30 Glezer Eli N. Assay cartridges and methods of using the same
US6811668B1 (en) 1999-06-22 2004-11-02 Caliper Life Sciences, Inc. Apparatus for the operation of a microfluidic device
US6824669B1 (en) 2000-02-17 2004-11-30 Motorola, Inc. Protein and peptide sensors using electrical detection methods
US6830729B1 (en) 1998-05-18 2004-12-14 University Of Washington Sample analysis instrument
US20040254559A1 (en) 2003-05-12 2004-12-16 Yokogawa Electric Corporation Chemical reaction cartridge, its fabrication method, and a chemical reaction cartridge drive system
US6833267B1 (en) 1998-12-30 2004-12-21 Clinical Micro Sensors, Inc. Tissue collection devices containing biosensors
US6857449B1 (en) 1998-01-20 2005-02-22 Caliper Life Sciences, Inc. Multi-layer microfluidic devices
US20050064423A1 (en) 2002-01-08 2005-03-24 Toshiro Higuchi Pcr method by electrostatic transportation, hybridization method for electrostatic transportation and devices therefor
US6875619B2 (en) 1999-11-12 2005-04-05 Motorola, Inc. Microfluidic devices comprising biochannels
US6881541B2 (en) 1999-05-28 2005-04-19 Cepheid Method for analyzing a fluid sample
US6881312B2 (en) 2000-03-27 2005-04-19 Caliper Life Sciences, Inc. Ultra high throughput microfluidic analytical systems and methods
US6914137B2 (en) 1997-12-06 2005-07-05 Dna Research Innovations Limited Isolation of nucleic acids
US6919444B2 (en) 1998-11-30 2005-07-19 Roche Diagnostics Gmbh Magnetic particles for purifying nucleic acids
US20050164373A1 (en) 2004-01-22 2005-07-28 Oldham Mark F. Diffusion-aided loading system for microfluidic devices
US20050182301A1 (en) 2003-01-31 2005-08-18 Zimmer Technology, Inc. Lit retractor
US6942771B1 (en) 1999-04-21 2005-09-13 Clinical Micro Sensors, Inc. Microfluidic systems in the electrochemical detection of target analytes
US6951759B2 (en) 2001-08-17 2005-10-04 Osmetech Plc Detection of bacterial vaginosis
US20050233440A1 (en) 2002-09-17 2005-10-20 Stmicroelectronics S.R.L. Apparatus for biochemical analysis
US6960437B2 (en) 2001-04-06 2005-11-01 California Institute Of Technology Nucleic acid amplification utilizing microfluidic devices
US20050244308A1 (en) 2004-04-28 2005-11-03 Takeo Tanaami Chemical reaction cartridge, method of producing chemical reaction cartridge, and mechanism for driving chemical reaction cartridge
US6967489B2 (en) 2001-11-13 2005-11-22 Caliper Life Sciences, Inc. Method and apparatus for controllably effecting samples using two signals
US6968978B1 (en) 2005-01-05 2005-11-29 William B Matthews Wall mountable dispenser for collapsible tubes
US6979424B2 (en) 1998-03-17 2005-12-27 Cepheid Integrated sample analysis device
US20060040379A1 (en) 2004-08-18 2006-02-23 Yokogawa Electric Corporation Biochip cartridge and biochip reader
US7010391B2 (en) 2001-03-28 2006-03-07 Handylab, Inc. Methods and systems for control of microfluidic devices
US7011791B2 (en) 2000-09-18 2006-03-14 University Of Washington Microfluidic devices for rotational manipulation of the fluidic interface between multiple flow streams
US20060057581A1 (en) 2002-11-01 2006-03-16 Norchip As Microfabricated fluidic device for fragmentation
US20060079834A1 (en) 2004-10-13 2006-04-13 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US7030989B2 (en) 2002-10-28 2006-04-18 University Of Washington Wavelength tunable surface plasmon resonance sensor
US7045285B1 (en) 1996-11-05 2006-05-16 Clinical Micro Sensors, Inc. Electronic transfer moieties attached to peptide nucleic acids
US7056475B2 (en) 2002-01-30 2006-06-06 Agilent Technologies, Inc. Fluidically isolated pumping and metered fluid delivery system and methods
US20060166233A1 (en) 2004-05-03 2006-07-27 Handylab, Inc. Method and apparatus for processing polynucleotide-containing samples
US7087148B1 (en) 1998-06-23 2006-08-08 Clinical Micro Sensors, Inc. Binding acceleration techniques for the detection of analytes
US20060183216A1 (en) 2005-01-21 2006-08-17 Kalyan Handique Containers for liquid storage and delivery with application to microfluidic devices
US7119194B2 (en) 1995-07-07 2006-10-10 Toyo Boseki Kabushiki Kaisha Nucleic acid-bondable magnetic carrier and method for isolating nucleic acid using the same
US20060246575A1 (en) 2005-01-13 2006-11-02 Micronics, Inc. Microfluidic rare cell detection device
US20060257993A1 (en) 2004-02-27 2006-11-16 Mcdevitt John T Integration of fluids and reagents into self-contained cartridges containing sensor elements
US20060264782A1 (en) 2005-05-09 2006-11-23 Holmes Elizabeth A Point-of-care fluidic systems and uses thereof
US7141429B2 (en) 2001-10-09 2006-11-28 University Of Washington Use of liquid junction potentials for electrophoresis without applied voltage in a microfluidic channel
US20060275852A1 (en) 2005-06-06 2006-12-07 Montagu Jean I Assays based on liquid flow over arrays
US20060275813A1 (en) 2005-06-03 2006-12-07 Yokogawa Electric Corporation Cartridge for chemical reaction
US7155344B1 (en) 1998-07-27 2006-12-26 Caliper Life Sciences, Inc. Distributed database for analytical instruments
US7160678B1 (en) 1996-11-05 2007-01-09 Clinical Micro Sensors, Inc. Compositions for the electronic detection of analytes utilizing monolayers
US7163612B2 (en) 2001-11-26 2007-01-16 Keck Graduate Institute Method, apparatus and article for microfluidic control via electrowetting, for chemical, biochemical and biological assays and the like
US20070013733A1 (en) 2005-07-15 2007-01-18 Yokogawa Electric Corporation Cartridge for chemical reaction and information managing apparatus
US20070017927A1 (en) 2005-07-07 2007-01-25 Roche Molecular Systems, Inc. Containers and methods for the automated handling of a liquid
US7172897B2 (en) 2000-01-11 2007-02-06 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
US20070042427A1 (en) 2005-05-03 2007-02-22 Micronics, Inc. Microfluidic laminar flow detection strip
US20070039974A1 (en) 2005-08-18 2007-02-22 Lloyd James J Dual-usage beverage dispensing system
US7192557B2 (en) 2001-03-28 2007-03-20 Handylab, Inc. Methods and systems for releasing intracellular material from cells within microfluidic samples of fluids
US7201881B2 (en) 2002-07-26 2007-04-10 Applera Corporation Actuator for deformable valves in a microfluidic device, and method
WO2007044917A2 (en) 2005-10-11 2007-04-19 Handylab, Inc. Polynucleotide sample preparation device
US7208271B2 (en) 2001-11-28 2007-04-24 Applera Corporation Compositions and methods of selective nucleic acid isolation
US7223371B2 (en) 2002-03-14 2007-05-29 Micronics, Inc. Microfluidic channel network device
US20070178529A1 (en) 2006-01-13 2007-08-02 Micronics, Inc. Electromagnetically actuated valves for use in microfluidic structures
US7258837B2 (en) 2001-12-05 2007-08-21 University Of Washington Microfluidic device and surface decoration process for solid phase affinity binding assays
US7270786B2 (en) 2001-03-28 2007-09-18 Handylab, Inc. Methods and systems for processing microfluidic samples of particle containing fluids
US20070219480A1 (en) 2006-02-09 2007-09-20 Dean Kamen Patch-sized fluid delivery systems and methods
WO2007112114A2 (en) 2006-03-24 2007-10-04 Handylab, Inc. Integrated system for processing microfluidic samples, and method of using same
US20070242105A1 (en) 2006-04-18 2007-10-18 Vijay Srinivasan Filler fluids for droplet operations
US20070241068A1 (en) 2006-04-13 2007-10-18 Pamula Vamsee K Droplet-based washing
WO2007120241A2 (en) 2006-04-18 2007-10-25 Advanced Liquid Logic, Inc. Droplet-based biochemistry
US20070248958A1 (en) 2004-09-15 2007-10-25 Microchip Biotechnologies, Inc. Microfluidic devices
US20070275415A1 (en) 2006-04-18 2007-11-29 Vijay Srinivasan Droplet-based affinity assays
US7312087B2 (en) 2000-01-11 2007-12-25 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
US7323140B2 (en) 2001-03-28 2008-01-29 Handylab, Inc. Moving microdroplets in a microfluidic device
US20080038810A1 (en) 2006-04-18 2008-02-14 Pollack Michael G Droplet-based nucleic acid amplification device, system, and method
US20080050287A1 (en) 2006-08-22 2008-02-28 Yokogawa Electric Corporation Chemical reaction apparatus
US20080056948A1 (en) 2006-09-06 2008-03-06 Canon U.S. Life Sciences, Inc. Chip and cartridge design configuration for performing micro-fluidic assays
US7364886B2 (en) 2006-02-28 2008-04-29 University Of Washington Chemical sensor enhanced by direct coupling of redox enzyme to conductive surface
US20080108122A1 (en) 2006-09-01 2008-05-08 State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon Microchemical nanofactories
US7371830B2 (en) 1995-06-08 2008-05-13 Roche Diagnostics Gmbh Method for separating biological material from a fluid using magnetic particles
US7393645B2 (en) 1996-11-05 2008-07-01 Clinical Micro Sensors, Inc. Compositions for the electronic detection of analytes utilizing monolayers
US7405054B1 (en) 2004-12-13 2008-07-29 University Of Washington Uw Tech Transfer - Invention Licensing Signal amplification method for surface plasmon resonance-based chemical detection
US20080182301A1 (en) 2006-03-24 2008-07-31 Kalyan Handique Microfluidic system for amplifying and detecting polynucleotides in parallel
US7416791B1 (en) 2002-06-11 2008-08-26 University Of Washington Osmium complexes and related organic light-emitting devices
US7416892B2 (en) 2003-01-21 2008-08-26 Micronics, Inc. Method and system for microfluidic manipulation, amplification and analysis of fluids, for example, bacteria assays and antiglobulin testing
US7419638B2 (en) 2003-01-14 2008-09-02 Micronics, Inc. Microfluidic devices for fluid manipulation and analysis
US20080227185A1 (en) 2004-01-28 2008-09-18 Norchip As Diagnostic System for Carrying Out a Nucleic Acid Sequence Amplification and Detection Process
US20080230386A1 (en) 2006-04-18 2008-09-25 Vijay Srinivasan Sample Processing Droplet Actuator, System and Method
US20080248590A1 (en) 2004-11-26 2008-10-09 Norchip As Device For Carrying Out A Biological Assay
US7439014B2 (en) 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
US20080274513A1 (en) 2005-05-11 2008-11-06 Shenderov Alexander D Method and Device for Conducting Biochemical or Chemical Reactions at Multiple Temperatures
US20080283439A1 (en) 2007-05-16 2008-11-20 Mystic Pharmaceuticals, Inc. Combination unit dose dispensing containers
US20080314167A1 (en) 2007-06-25 2008-12-25 Valentin Kahl Sample Chamber
US7473397B2 (en) 2001-12-13 2009-01-06 The Technology Partnership Plc Device for chemical or biochemical analysis
US7491495B2 (en) 2004-02-20 2009-02-17 Roche Diagnostics Operations, Inc. Adsorption of nucleic acids to a solid phase
US20090061450A1 (en) 2006-03-14 2009-03-05 Micronics, Inc. System and method for diagnosis of infectious diseases
US7544506B2 (en) 2003-06-06 2009-06-09 Micronics, Inc. System and method for heating, cooling and heat cycling on microfluidic device
US20090148847A1 (en) 2006-03-15 2009-06-11 Micronics, Inc. Rapid magnetic flow assays
US20090155902A1 (en) 2006-04-18 2009-06-18 Advanced Liquid Logic, Inc. Manipulation of Cells on a Droplet Actuator
US7550267B2 (en) 2004-09-23 2009-06-23 University Of Washington Microscale diffusion immunoassay utilizing multivalent reactants
US20090171311A1 (en) 2007-12-28 2009-07-02 Aktivpak, Inc. Dispenser and therapeutic package suitable for administering a therapeutic substance to a subject, along with method relating to same
US7560237B2 (en) 1997-06-12 2009-07-14 Osmetech Technology Inc. Electronics method for the detection of analytes
US20090180931A1 (en) 2007-09-17 2009-07-16 Sequenom, Inc. Integrated robotic sample transfer device
US20090182575A1 (en) 2008-01-11 2009-07-16 General Electric Company System and method to manage a workflow in delivering healthcare
US20090197778A1 (en) 2006-06-27 2009-08-06 Zenteris Gmbh Heated Reaction Chamber For Processing A Biochip And Method For Controlling Said Reaction Chamber
US20090221059A1 (en) 2007-07-13 2009-09-03 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US20090221091A1 (en) 2008-03-03 2009-09-03 Yokogawa Electric Corporation Chemical reaction cartridge, mixture generating method and control device of chemical reaction cartridge
USD599832S1 (en) 2008-02-25 2009-09-08 Advanced Liquid Logic, Inc. Benchtop instrument housing
US20090223989A1 (en) 2008-03-04 2009-09-10 R.J. Reynolds Tobacco Company Dispensing Container
USD600503S1 (en) 2008-07-29 2009-09-22 Ragsdale Donald W Food tray with waste collection feature
US20090263834A1 (en) 2006-04-18 2009-10-22 Advanced Liquid Logic, Inc. Droplet Actuator Devices and Methods for Immunoassays and Washing
US7607460B2 (en) 2006-06-12 2009-10-27 Jpro Dairy International, Inc. Coupling assembly
US20090298059A1 (en) 2005-05-25 2009-12-03 Walter Gumbrecht System for the Integrated and Automated Analysis of DNA or Protein and Method for Operating Said Type of System
US20090304944A1 (en) 2007-01-22 2009-12-10 Advanced Liquid Logic, Inc. Surface Assisted Fluid Loading and Droplet Dispensing
US20090325276A1 (en) 2006-09-27 2009-12-31 Micronics, Inc. Integrated microfluidic assay devices and methods
US7644898B2 (en) 2005-03-28 2010-01-12 Compview Medical, Llc Medical boom with articulated arms and a base with preconfigured removable modular racks used for storing electronic and utility equipment
US7648835B2 (en) 2003-06-06 2010-01-19 Micronics, Inc. System and method for heating, cooling and heat cycling on microfluidic device
US20100021910A1 (en) 2008-07-18 2010-01-28 Canon U.S. Life Sciences, Inc. Methods and Systems for Microfluidic DNA Sample Preparation
US7655190B2 (en) 2006-08-03 2010-02-02 Yokogawa Electric Corporation Biochemical reaction apparatus and biochemical reaction method
US20100025250A1 (en) 2007-03-01 2010-02-04 Advanced Liquid Logic, Inc. Droplet Actuator Structures
US20100032293A1 (en) 2007-04-10 2010-02-11 Advanced Liquid Logic, Inc. Droplet Dispensing Device and Methods
US20100035349A1 (en) 2008-08-06 2010-02-11 The Trustees Of The University Of Pennsylvania Biodetection Cassette with Automated Actuator
US20100048410A1 (en) 2007-03-22 2010-02-25 Advanced Liquid Logic, Inc. Bead Sorting on a Droplet Actuator
US7670559B2 (en) 2001-02-15 2010-03-02 Caliper Life Sciences, Inc. Microfluidic systems with enhanced detection systems
WO2010025302A2 (en) 2008-08-27 2010-03-04 Life Technologies Corporation Apparatus for and method of processing biological samples
US20100068764A1 (en) 2007-02-09 2010-03-18 Advanced Liquid Logic, Inc. Droplet Actuator Devices and Methods Employing Magnetic Beads
US20100087012A1 (en) 2007-04-23 2010-04-08 Advanced Liquid Logic, Inc. Sample Collector and Processor
US20100093019A1 (en) 2007-01-12 2010-04-15 Environmental Biotechnology Crc Pty Limited Sample handling device
US20100120130A1 (en) 2007-08-08 2010-05-13 Advanced Liquid Logic, Inc. Droplet Actuator with Droplet Retention Structures
US20100130369A1 (en) 2007-04-23 2010-05-27 Advanced Liquid Logic, Inc. Bead-Based Multiplexed Analytical Methods and Instrumentation
US7727723B2 (en) 2006-04-18 2010-06-01 Advanced Liquid Logic, Inc. Droplet-based pyrosequencing
US20100136554A1 (en) 2007-04-25 2010-06-03 3M Innovative Properties Company Supported reagents, methods, and devices
US7731906B2 (en) 2003-07-31 2010-06-08 Handylab, Inc. Processing particle-containing samples
US7736891B2 (en) 2007-09-11 2010-06-15 University Of Washington Microfluidic assay system with dispersion monitoring
US20100173394A1 (en) 2008-09-23 2010-07-08 Colston Jr Billy Wayne Droplet-based assay system
US20100178697A1 (en) 2008-01-09 2010-07-15 Keck Graduate Institute System, apparatus and method for material preparation and/or handling
US7763471B2 (en) 2006-04-18 2010-07-27 Advanced Liquid Logic, Inc. Method of electrowetting droplet operations for protein crystallization
US7763453B2 (en) 2005-11-30 2010-07-27 Micronics, Inc. Microfluidic mixing and analytic apparatus
US20100190263A1 (en) 2009-01-23 2010-07-29 Advanced Liquid Logic, Inc. Bubble Techniques for a Droplet Actuator
US20100194408A1 (en) 2007-02-15 2010-08-05 Advanced Liquid Logic, Inc. Capacitance Detection in a Droplet Actuator
US20100206094A1 (en) 2007-04-23 2010-08-19 Advanced Liquid Logic, Inc. Device and Method for Sample Collection and Concentration
US7789270B2 (en) 2005-09-27 2010-09-07 Yokogawa Electric Corporation Chemical reaction cartridge and method using same
US20100224511A1 (en) 2009-03-06 2010-09-09 Barry Boatner Bifurcated beverage can with unified opening and mixing operation
US7794669B2 (en) 2007-01-17 2010-09-14 Yokogawa Electric Corporation Chemical reaction cartridge
US20100233824A1 (en) 2007-07-20 2010-09-16 Koninklijke Philips Electronics N.V. Microfluidic methods and systems for use in detecting analytes
US20100236928A1 (en) 2007-10-17 2010-09-23 Advanced Liquid Logic, Inc. Multiplexed Detection Schemes for a Droplet Actuator
US20100236929A1 (en) 2007-10-18 2010-09-23 Advanced Liquid Logic, Inc. Droplet Actuators, Systems and Methods
US7815871B2 (en) 2006-04-18 2010-10-19 Advanced Liquid Logic, Inc. Droplet microactuator system
US7822510B2 (en) 2006-05-09 2010-10-26 Advanced Liquid Logic, Inc. Systems, methods, and products for graphically illustrating and controlling a droplet actuator
US7820030B2 (en) 2003-04-16 2010-10-26 Handylab, Inc. System and method for electrochemical detection of biological compounds
US7820391B2 (en) 2007-11-06 2010-10-26 Osmetech Molecular Diagnostics Baseless nucleotide analogues and uses thereof
US20100270156A1 (en) 2007-12-23 2010-10-28 Advanced Liquid Logic, Inc. Droplet Actuator Configurations and Methods of Conducting Droplet Operations
US20100279374A1 (en) 2006-04-18 2010-11-04 Advanced Liquid Logic, Inc. Manipulation of Beads in Droplets and Methods for Manipulating Droplets
US20100282608A1 (en) 2007-09-04 2010-11-11 Advanced Liquid Logic, Inc. Droplet Actuator with Improved Top Substrate
US20100282609A1 (en) 2007-10-17 2010-11-11 Advanced Liquid Logic, Inc. Reagent Storage and Reconstitution for a Droplet Actuator
US20100291588A1 (en) 2005-06-24 2010-11-18 The Board Of Regents Of The University Of Texas System Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
US20100297754A1 (en) 2007-06-07 2010-11-25 Norchip A/S Device for carrying out cell lysis and nucleic acid extraction
US20100304986A1 (en) 2006-12-14 2010-12-02 The Trustees Of The University Of Pennsylvania Mechanically actuated diagnostic device
US20100307917A1 (en) 2007-12-10 2010-12-09 Advanced Liquid Logic, Inc. Droplet Actuator Configurations and Methods
US20100307922A1 (en) 2007-05-24 2010-12-09 Digital Biosystems Electrowetting based digital microfluidics
US20100311599A1 (en) 2008-02-11 2010-12-09 Wheeler Aaron R Cell culture and cell assays using digital microfluidics
US20100308051A1 (en) 2007-12-06 2010-12-09 Lutz Weber Microfluid storage device
US20100317093A1 (en) 2009-06-10 2010-12-16 Cynvenio Biosystems, Inc. Flexible pouch and cartridge with fluidic circuits
US20100323405A1 (en) 2007-06-22 2010-12-23 Advanced Liquid Logic, Inc. Droplet-Based Nucleic Acid Amplification in a Temperature Gradient
US7858045B2 (en) 2005-09-30 2010-12-28 Yokogawa Electric Corporation Chemical reaction cartridge and method of using same
US20100331522A1 (en) 2009-06-26 2010-12-30 Bruce Irvine Capture and elution of bio-analytes via beads that are used to disrupt specimens
US7863035B2 (en) 2007-02-15 2011-01-04 Osmetech Technology Inc. Fluidics devices
US7867757B2 (en) 2001-12-28 2011-01-11 Norchip As Fluid manipulation in a microfabricated reaction chamber systems
US20110048951A1 (en) 2007-06-27 2011-03-03 Digital Biosystems Digital microfluidics based apparatus for heat-exchanging chemical processes
US20110053289A1 (en) 2006-03-29 2011-03-03 Inverness Medical Switzerland Gmbh Assay Device and Method
US7901947B2 (en) 2006-04-18 2011-03-08 Advanced Liquid Logic, Inc. Droplet-based particle sorting
US7910294B2 (en) 2000-12-05 2011-03-22 Norchip A/S Ligand detection method
US7914994B2 (en) 1998-12-24 2011-03-29 Cepheid Method for separating an analyte from a sample
US20110076692A1 (en) 2009-09-29 2011-03-31 Ramakrishna Sista Detection of Cardiac Markers on a Droplet Actuator
US7919330B2 (en) 2005-06-16 2011-04-05 Advanced Liquid Logic, Inc. Method of improving sensor detection of target molcules in a sample within a fluidic system
US20110086377A1 (en) 2007-08-24 2011-04-14 Advanced Liquid Logic, Inc. Bead Manipulations on a Droplet Actuator
US20110091989A1 (en) 2006-04-18 2011-04-21 Advanced Liquid Logic, Inc. Method of Reducing Liquid Volume Surrounding Beads
US20110097763A1 (en) 2008-05-13 2011-04-28 Advanced Liquid Logic, Inc. Thermal Cycling Method
US7935537B2 (en) 2004-03-11 2011-05-03 Handylab, Inc. Sample preparation device and method
US7935316B2 (en) 2007-01-16 2011-05-03 Yokogawa Electric Corporation Chemical reaction cartridge and method for using
US7935481B1 (en) 1999-07-26 2011-05-03 Osmetech Technology Inc. Sequence determination of nucleic acids using electronic detection
US20110104747A1 (en) 2006-05-09 2011-05-05 Advanced Liquid Logic, Inc. Method of Concentrating Beads in a Droplet
US20110104816A1 (en) 2008-05-03 2011-05-05 Advanced Liquid Logic, Inc. Method of Loading a Droplet Actuator
US20110104725A1 (en) 2008-05-02 2011-05-05 Advanced Liquid Logic, Inc. Method of Effecting Coagulation in a Droplet
US7939021B2 (en) 2007-05-09 2011-05-10 Advanced Liquid Logic, Inc. Droplet actuator analyzer with cartridge
US20110114490A1 (en) 2006-04-18 2011-05-19 Advanced Liquid Logic, Inc. Bead Manipulation Techniques
US20110129931A1 (en) 2009-10-20 2011-06-02 Agency For Science, Technology And Research Microfluidic system for detecting a biological entity in a sample
US20110143339A1 (en) 2007-08-17 2011-06-16 Craig Wisniewski Device, System and Method for Processing a Sample
US20110159578A1 (en) 2009-09-15 2011-06-30 James Hal Godsey Multiple-input Analytical System
JP2011520449A (en) 2008-05-13 2011-07-21 アドヴァンスト リキッド ロジック インコーポレイテッド Droplet actuator device, system, and method
US20110180571A1 (en) 2006-04-18 2011-07-28 Advanced Liquid Logic, Inc. Droplet Actuators, Modified Fluids and Methods
US20110186466A1 (en) 2008-06-19 2011-08-04 Boehringer Ingelheim Microparts Gmbh Fluid metering container
US20110207621A1 (en) 2008-02-21 2011-08-25 Avantra Biosciences Corporation Assays Based on Liquid Flow over Arrays
US20110203930A1 (en) 2006-04-18 2011-08-25 Advanced Liquid Logic, Inc. Bead Incubation and Washing on a Droplet Actuator
US20110207209A1 (en) 2010-02-17 2011-08-25 Aaron Hammons Culture systems, apparatus, and related methods and articles
WO2011106314A2 (en) 2010-02-25 2011-09-01 Advanced Liquid Logic, Inc. Method of making nucleic acid libraries
US8017340B2 (en) 2004-12-23 2011-09-13 Abbott Point Of Care Inc. Nucleic acid separation and amplification
US20110240471A1 (en) 2008-10-01 2011-10-06 Tecan Trading Ag Exchangeable carriers pre-loaded with reagent depots for digital microfluidics
WO2011127040A2 (en) 2010-04-09 2011-10-13 Molecular Devices, Inc. High throughput screening of ion channels
US8041463B2 (en) 2006-05-09 2011-10-18 Advanced Liquid Logic, Inc. Modular droplet actuator drive
US8048628B2 (en) 2002-09-24 2011-11-01 Duke University Methods for nucleic acid amplification on a printed circuit board
US8053239B2 (en) 2008-10-08 2011-11-08 The Governing Council Of The University Of Toronto Digital microfluidic method for protein extraction by precipitation from heterogeneous mixtures
US20110303542A1 (en) 2007-08-08 2011-12-15 Advanced Liquid Logic, Inc. Use of Additives for Enhancing Droplet Operations
JP2011252768A (en) 2010-06-01 2011-12-15 Sharp Corp Micro analysis chip, analyzer using the same and liquid feeding method
US20110311980A1 (en) 2008-12-15 2011-12-22 Advanced Liquid Logic, Inc. Nucleic Acid Amplification and Sequencing on a Droplet Actuator
US20110318824A1 (en) 2010-05-31 2011-12-29 Yokogawa Electric Corporation Cartridge system for chemical processing
US8093062B2 (en) 2007-03-22 2012-01-10 Theodore Winger Enzymatic assays using umbelliferone substrates with cyclodextrins in droplets in oil
US8101403B2 (en) 2006-10-04 2012-01-24 University Of Washington Method and device for rapid parallel microfluidic molecular affinity assays
US8101431B2 (en) 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US8110392B2 (en) 2006-06-23 2012-02-07 Micronics, Inc. Methods and devices for microfluidic point-of-care immunoassays
US20120044299A1 (en) 2009-08-14 2012-02-23 Advanced Liquid Logic, Inc. Droplet Actuator Devices and Methods
US8129118B2 (en) 1995-06-08 2012-03-06 Roche Diagnostics Gmbh Magnetic glass particles, method for their preparation and uses thereof
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8133703B2 (en) 2004-10-27 2012-03-13 Ceoheid Closed-system multi-stage nucleic acid amplification reactions
US20120071342A1 (en) 2010-09-15 2012-03-22 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
US20120083046A1 (en) 2008-10-10 2012-04-05 The Governing Council Of The University Of Toronto Hybrid digital and channel microfluidic devices and methods of use thereof
US20120085645A1 (en) 2009-02-26 2012-04-12 The Governing Council Of The University Of Toronto Digital microfluidic liquid-liquid extraction device and method of use thereof
US8168442B2 (en) 1999-05-28 2012-05-01 Cepheid Cartridge for conducting a chemical reaction
US20120107811A1 (en) 2009-02-06 2012-05-03 Kelso David M Burstable liquid packaging and uses thereof
US20120142070A1 (en) 2009-06-12 2012-06-07 Micronics, Inc. Rehydratable matrices for dry storage of taq polymerase in a microfluidic device
US8201765B2 (en) 2008-09-08 2012-06-19 California Institute Of Technology Mechanical lysis arrangements and methods
US8202736B2 (en) 2009-02-26 2012-06-19 The Governing Council Of The University Of Toronto Method of hormone extraction using digital microfluidics
US8202686B2 (en) 2007-03-22 2012-06-19 Advanced Liquid Logic, Inc. Enzyme assays for a droplet actuator
US20120156750A1 (en) 2009-06-12 2012-06-21 Micronics, Inc. Compositions and methods for dehydrated storage of on-board reagents in microfluidic devices
US20120156112A1 (en) 2009-04-13 2012-06-21 Micronics, Inc. Microfluidic clinical analyzer
US8208146B2 (en) 2007-03-13 2012-06-26 Advanced Liquid Logic, Inc. Droplet actuator devices, configurations, and methods for improving absorbance detection
US20120160826A1 (en) 2006-03-24 2012-06-28 Handylab, Inc. Heater unit for microfluidic diagnostic system
US8216832B2 (en) 2007-07-31 2012-07-10 Micronics, Inc. Sanitary swab collection system, microfluidic assay device, and methods for diagnostic assays
US8216529B2 (en) 2008-09-15 2012-07-10 Abbott Point Of Care Inc. Fluid-containing pouches with reduced gas exchange and methods for making same
US20120177543A1 (en) 2005-11-30 2012-07-12 Micronics, Inc. Microfluidic reactor system
US20120187117A1 (en) 2009-07-11 2012-07-26 Thinxxs Microtechnology Ag Fluid reservoir
US20120196280A1 (en) 2009-07-17 2012-08-02 Norchip A/S Microfabricated device for metering an analyte
US8247191B2 (en) 2008-11-13 2012-08-21 Ritzen Kalle Disposable cassette and method of use for blood analysis on blood analyzer
US8268246B2 (en) 2007-08-09 2012-09-18 Advanced Liquid Logic Inc PCB droplet actuator fabrication
US20120252008A1 (en) 2010-12-23 2012-10-04 Claremont Biosolutions, Llc Compositions and methods for capture and elution of biological materials via particulates
US20120261264A1 (en) 2008-07-18 2012-10-18 Advanced Liquid Logic, Inc. Droplet Operations Device
US20120270305A1 (en) 2011-01-10 2012-10-25 Illumina Inc. Systems, methods, and apparatuses to image a sample for biological or chemical analysis
US8304253B2 (en) 2005-10-22 2012-11-06 Advanced Liquid Logic Inc Droplet extraction from a liquid column for on-chip microfluidics
WO2012151192A2 (en) 2011-05-02 2012-11-08 Advanced Liquid Logic, Inc. Molecular diagnostics platform
US8317990B2 (en) 2007-03-23 2012-11-27 Advanced Liquid Logic Inc. Droplet actuator loading and target concentration
US8318439B2 (en) 2008-10-03 2012-11-27 Micronics, Inc. Microfluidic apparatus and methods for performing blood typing and crossmatching
US8329453B2 (en) 2009-01-30 2012-12-11 Micronics, Inc. Portable high gain fluorescence detection system
US8338166B2 (en) 2007-01-04 2012-12-25 Lawrence Livermore National Security, Llc Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture
US8342367B2 (en) 2008-10-16 2013-01-01 Automatic Bar Controls, Inc. Cassette and vat supply source for an on-demand mixing and distributing of a food product
US8343636B2 (en) 2006-05-09 2013-01-01 University Of Washington Crosslinkable hole-transporting materials for organic light-emitting devices
US20130018611A1 (en) 2011-07-11 2013-01-17 Advanced Liquid Logic Inc Systems and Methods of Measuring Gap Height
US20130017544A1 (en) 2011-07-11 2013-01-17 Advanced Liquid Logic Inc High Resolution Melting Analysis on a Droplet Actuator
US20130020202A1 (en) 2011-07-22 2013-01-24 Feiglin Marc N Cartridge and System for Manipulating Samples in Liquid Droplets
US8364315B2 (en) 2008-08-13 2013-01-29 Advanced Liquid Logic Inc. Methods, systems, and products for conducting droplet operations
US8372340B2 (en) 2005-10-19 2013-02-12 Luminex Corporation Apparatus and methods for integrated sample preparation, reaction and detection
US20130059366A1 (en) 2009-11-06 2013-03-07 Duke University Integrated Droplet Actuator for Gel; Electrophoresis and Molecular Analysis
US8394641B2 (en) 2009-12-21 2013-03-12 Advanced Liquid Logic Inc. Method of hydrolyzing an enzymatic substrate
US8394608B2 (en) 2005-05-09 2013-03-12 Biofire Diagnostics, Inc. Self-contained biological analysis
US8426214B2 (en) 2009-06-12 2013-04-23 University Of Washington System and method for magnetically concentrating and detecting biomarkers
US8426213B2 (en) 2007-03-05 2013-04-23 Advanced Liquid Logic Inc Hydrogen peroxide droplet-based assays
WO2013059750A1 (en) 2011-10-21 2013-04-25 Integenx Inc. Sample preparation, processing and analysis systems
US8440392B2 (en) 2007-03-22 2013-05-14 Advanced Liquid Logic Inc. Method of conducting a droplet based enzymatic assay
US20130130262A1 (en) 2010-01-29 2013-05-23 C. Frederick Battrell Sample-to-answer microfluidic cartridge
US8454905B2 (en) 2007-10-17 2013-06-04 Advanced Liquid Logic Inc. Droplet actuator structures
US8470606B2 (en) 2006-04-18 2013-06-25 Duke University Manipulation of beads in droplets and methods for splitting droplets
US8481125B2 (en) 2005-05-21 2013-07-09 Advanced Liquid Logic Inc. Mitigation of biomolecular adsorption with hydrophilic polymer additives
US20130178374A1 (en) 2011-07-06 2013-07-11 Advanced Liquid Logic, Inc. Systems for and Methods of Hybrid Pyrosequencing
US8506908B2 (en) 2007-03-09 2013-08-13 Vantix Holdings Limited Electrochemical detection system
US20130217113A1 (en) 2010-07-15 2013-08-22 Advanced Liquid Logic Inc. System for and methods of promoting cell lysis in droplet actuators
US20130217103A1 (en) 2010-03-30 2013-08-22 Advanced Liquid Logic Inc Droplet Operations Platform
US20130252262A1 (en) 2006-04-13 2013-09-26 Advanced Liquid Logic Inc. Droplet-based affinity assays
US8551424B2 (en) 2005-11-17 2013-10-08 Siemens Aktiengesellschaft Apparatus for processing a sample comprising a biochip and reagents embedded in a biodegradable material, and processes thereof
US8580209B2 (en) 2008-06-02 2013-11-12 Boehringer Ingelheim Microparts Gmbh Microfluidic foil structure for metering of fluids
US20130302787A1 (en) 2012-05-08 2013-11-14 Northwestern University Cartridge for use in an automated system for isolating an analyte from a sample, and methods of use
US20130327672A1 (en) 2010-11-10 2013-12-12 Boehringer Ingelheim Microparts Gmbh Blister packaging for liquid and use thereof and method for supplying a liquid to a fluidic assembly
US20130331298A1 (en) 2012-06-06 2013-12-12 Great Basin Scientific Analyzer and disposable cartridge for molecular in vitro diagnostics
US20130341231A1 (en) 2010-11-10 2013-12-26 Boehringer Ingelheim Microparts Gmbh Blister packaging for liquid
US20140000223A1 (en) 2010-11-10 2014-01-02 Boehringer Ingelheim Microparts Gmbh Method for filling a blister packaging with liquid, and blister packaging with a cavity for filling with liquid
US20140000735A1 (en) 2012-06-28 2014-01-02 Thinxxs Microtechnology Ag Micro reservoir, particularly for integration in a microfluidic flow cell
US20140045275A1 (en) 2011-02-15 2014-02-13 Robert Bosch Gmbh Apparatus for hermetically sealed storage of liquids for a microfluidic system
WO2014049371A2 (en) 2012-09-28 2014-04-03 Agplus Diagnostics Ltd Test device and sample carrier
USD702364S1 (en) 2011-12-20 2014-04-08 SYFR, Inc. Auto-staining cartridge
US8701906B1 (en) 2008-12-31 2014-04-22 Blast Max Llc Ingredient dispensing cap for mixing beverages with push-pull drinking spout
WO2014066704A1 (en) 2012-10-24 2014-05-01 Genmark Diagnostics, Inc. Integrated multiplex target analysis
US20140160877A1 (en) 2010-12-20 2014-06-12 Boehringer Ingelheim Microparts Gmbh Method for mixing at least one sample solution having at least one reagent, and device
US20140170641A1 (en) 2012-12-19 2014-06-19 Nanomr, Inc. Sample entry
US20140220702A1 (en) 2013-01-31 2014-08-07 Luminex Corporation Fluid retention plates and analysis cartridges
US20140252079A1 (en) 2013-03-11 2014-09-11 Promega Corporation Analyzer with machine readable protocol prompting
US20140255275A1 (en) 2013-03-07 2014-09-11 Quidel Corporation Dual chamber liquid packaging system
US20140261708A1 (en) 2013-03-15 2014-09-18 Genmark Diagnostics, Inc. Devices and methods for manipulating deformable fluid vessels
US20140322706A1 (en) 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
US20140370609A1 (en) 2013-04-05 2014-12-18 Roche Molecular Systems, Inc. Analysis system for a biological sample
US20150024436A1 (en) 2011-10-21 2015-01-22 Integenx Inc, Sample preparation, processing and analysis systems
US20150132860A1 (en) 2012-05-15 2015-05-14 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
US20150346097A1 (en) 2012-12-21 2015-12-03 Micronics, Inc. Portable fluorescence detection system and microassay cartridge
WO2015191916A1 (en) 2014-06-11 2015-12-17 Micronics, Inc. Microfluidic cartridges and apparatus with integrated assay controls for analysis of nucleic acids
US20160129445A1 (en) 2014-11-11 2016-05-12 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
US20160130640A1 (en) 2014-11-11 2016-05-12 Genmark Diagnostics, Inc. Cartridge for performing assays in a closed sample preparation and reaction system
US20160131672A1 (en) 2014-11-11 2016-05-12 Genmark Diagnostics, Inc. Redundant identification for sample tracking on a diagnostic device
US20160129437A1 (en) 2014-11-11 2016-05-12 Advanced Liquid Logic, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation
US20160146803A1 (en) 2013-01-25 2016-05-26 Carclo Technical Plastics Limited Heterogenous assay
US20170181314A1 (en) 2015-12-17 2017-06-22 Hewlett Packard Enterprise Development Lp Bay for removable device
USD800337S1 (en) 2016-01-27 2017-10-17 Phd Preventative Health Care And Diagnostics, Inc. Medical tray assembly
USD804808S1 (en) 2015-09-01 2017-12-12 Comprehensive Telemedicine Storage and carry case for telemedicine devices
US20180015454A1 (en) 2016-07-12 2018-01-18 Wi, Inc. Disposable diagnostic device with vented priming fluid passage for volumetric control of sample and reagents and method of performing a diagnosis therewith
US20180095100A1 (en) 2016-09-19 2018-04-05 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
USD815754S1 (en) 2014-05-16 2018-04-17 Cytonome/St, Llc Droplet sorter
USD815752S1 (en) 2014-11-28 2018-04-17 Randox Laboratories Ltd. Biochip well
USD819225S1 (en) * 2017-01-19 2018-05-29 Life Technologies Corporation Capillary electrophoresis instrument
USD830573S1 (en) 2017-05-30 2018-10-09 Qualigen, Inc. Reagent pack
USD831224S1 (en) 2017-03-23 2018-10-16 Bonraybio Co., Ltd. Test strip
USD845503S1 (en) * 2017-11-17 2019-04-09 Genmark Diagnostics, Inc. Instrument
USD881409S1 (en) 2013-10-24 2020-04-14 Genmark Diagnostics, Inc. Biochip cartridge

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634003A (en) 1984-08-22 1987-01-06 Suntory Limited Container for accommodating two kinds of liquids
US5567588A (en) 1990-06-11 1996-10-22 University Research Corporation Systematic evolution of ligands by exponential enrichment: Solution SELEX
US5637459A (en) 1990-06-11 1997-06-10 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: chimeric selex
US5705337A (en) 1990-06-11 1998-01-06 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: chemi-SELEX
US5683867A (en) 1990-06-11 1997-11-04 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: blended SELEX
US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
US5496938A (en) 1990-06-11 1996-03-05 Nexstar Pharmaceuticals, Inc. Nucleic acid ligands to HIV-RT and HIV-1 rev
CA2084987C (en) 1990-06-11 2007-02-13 Larry Gold Nucleic acid ligands
AU647609B2 (en) 1991-04-18 1994-03-24 Becton Dickinson & Company Microbial monitoring device
US5505877A (en) 1991-10-15 1996-04-09 Krivohlavek; Dennis Making multiple phase emulsion or gel
US5798215A (en) * 1993-02-18 1998-08-25 Biocircuits Corporation Device for use in analyte detection assays
DE19638790A1 (en) 1996-09-21 1998-03-26 Mann & Hummel Filter Air filter
WO1998020162A2 (en) 1996-11-05 1998-05-14 Clinical Micro Sensors Electrodes linked via conductive oligomers to nucleic acids
EP1075541A1 (en) 1998-05-06 2001-02-14 Clinical Micro Sensors Electronic detection of nucleic acids using monolayers
JP4530541B2 (en) 1998-09-17 2010-08-25 クリニカル・マイクロ・センサーズ・インコーポレイテッド Signal detection method for analyte detection
JP2002533694A (en) 1998-12-30 2002-10-08 クリニカル・マイクロ・センサーズ・インコーポレイテッド Tissue collection device with biosensor
US6561727B1 (en) 1999-04-12 2003-05-13 Thomas F. Gustafson, Jr. Ergonomic hybrid transit access corridor particularly for town and urban centers
BR0012965A (en) 1999-08-04 2003-07-29 Nini Policappelli Multicellular container
US6811752B2 (en) * 2001-05-15 2004-11-02 Biocrystal, Ltd. Device having microchambers and microfluidics
JP2003222633A (en) * 2002-01-30 2003-08-08 Nippon Sheet Glass Co Ltd Microchip
DK1518011T3 (en) 2002-06-28 2013-06-17 Neokidney Holding B V Process for the preparation of functional porous fibers
SE524730C2 (en) * 2002-11-20 2004-09-21 Boule Medical Ab Blood Unit
US7682833B2 (en) * 2003-09-10 2010-03-23 Abbott Point Of Care Inc. Immunoassay device with improved sample closure
WO2005083423A2 (en) 2004-02-27 2005-09-09 Board Of Regents, The University Of Texas System System and method for integrating fluids and reagents in self-contained cartridges containing particle and membrane sensor elements
KR100552706B1 (en) * 2004-03-12 2006-02-20 삼성전자주식회사 Method and apparatus for nucleic acid amplification
DE102004022423A1 (en) * 2004-05-06 2005-12-15 Siemens Ag microfluidic
JP2006094741A (en) * 2004-09-29 2006-04-13 Canon Inc Biochemical reaction treatment apparatus and biochemical reaction treatment method
JP2006223126A (en) * 2005-02-15 2006-08-31 Shimadzu Corp Reaction vessel, method and apparatus for detecting genetic polymorphism and method and apparatus for diagnosis
WO2006102708A1 (en) 2005-04-01 2006-10-05 Resmed Limited Mask pressure regulation in cpap treatment and assisted respiration by dynamic control of mask vent flow
US9568424B2 (en) * 2005-06-23 2017-02-14 Biocartis Nv Cartridge, system and method for automated medical diagnostics
US20070032081A1 (en) 2005-08-08 2007-02-08 Jeremy Chang Edge ring assembly with dielectric spacer ring
US8541177B2 (en) 2006-01-13 2013-09-24 A Chan Holding B.V. Treatment and diagnosis of abnormal bone density with an inhibitor of the glypican-sclerostin interaction
CN101384846A (en) * 2006-02-13 2009-03-11 皇家飞利浦电子股份有限公司 Microfluidic device for molecular diagnostic applications
JP4593517B2 (en) * 2006-05-15 2010-12-08 株式会社日立ハイテクノロジーズ Chemical analyzer
US7851384B2 (en) 2006-06-01 2010-12-14 Applied Materials, Inc. Method to mitigate impact of UV and E-beam exposure on semiconductor device film properties by use of a bilayer film
JP4759451B2 (en) * 2006-06-16 2011-08-31 株式会社日立ソリューションズ Pretreatment chip for biological material and pretreatment chip system
US20080069732A1 (en) * 2006-09-20 2008-03-20 Robert Yi Diagnostic test system
GB0618966D0 (en) * 2006-09-26 2006-11-08 Iti Scotland Ltd Cartridge system
US9266076B2 (en) * 2006-11-02 2016-02-23 The Regents Of The University Of California Method and apparatus for real-time feedback control of electrical manipulation of droplets on chip
EP2191897B1 (en) * 2007-06-21 2014-02-26 Gen-Probe Incorporated Instrument and receptacles for performing processes
US8709395B2 (en) 2007-10-29 2014-04-29 Ayman Boutros Method for repairing or replacing damaged tissue
JP2009134512A (en) * 2007-11-30 2009-06-18 Brother Ind Ltd Information processor and information processing program
JP5046298B2 (en) * 2007-12-28 2012-10-10 株式会社吉野工業所 Two-component mixing container
US7919062B2 (en) * 2008-03-20 2011-04-05 Corning Incorporated Modular microfluidic system and method for building a modular microfludic system
US20110137018A1 (en) * 2008-04-16 2011-06-09 Cynvenio Biosystems, Inc. Magnetic separation system with pre and post processing modules
CA2723707C (en) * 2008-05-09 2016-08-23 Akonni Biosystems Microarray system
JP2009284373A (en) 2008-05-26 2009-12-03 Nippon Sheet Glass Co Ltd Ultraviolet-rays line lighting apparatus, contact image sensor, image reading apparatus, and reductive optical system image reading apparatus
FR2933316B1 (en) * 2008-07-07 2010-09-10 Commissariat Energie Atomique MICROFLUID DEVICE FOR DISPLACING LIQUID CONTROL
EP2344679B1 (en) * 2008-09-24 2018-05-23 First Light Biosciences, Inc. Kits and devices for detecting analytes
CH700127A1 (en) 2008-12-17 2010-06-30 Tecan Trading Ag System and apparatus for processing biological samples and for manipulating liquids with biological samples.
WO2010093027A1 (en) 2009-02-13 2010-08-19 Kagawa Seiji Metal thin film-plastic film composite film with linear streaks and apparatus for producing same
KR101395003B1 (en) 2009-03-20 2014-05-14 유니페르시타이트 안트베르펜 Surface-modified inorganic matrix and method for preparation thereof
JP5146399B2 (en) * 2009-04-27 2013-02-20 横河電機株式会社 Chemical reaction cartridge and drive mechanism thereof
JP2009199617A (en) * 2009-05-07 2009-09-03 Sony Corp Information processing device and method
JP5428551B2 (en) 2009-06-05 2014-02-26 ダイキン工業株式会社 Trailer refrigeration equipment
US9250234B2 (en) 2011-01-19 2016-02-02 Ohmx Corporation Enzyme triggered redox altering chemical elimination (E-TRACE) immunoassay
EP2642291B1 (en) * 2009-08-07 2015-10-07 Ohmx Corporation Enzyme triggered redox altering chemical elimination (E-trace) immunoassay
US8715476B2 (en) * 2009-12-11 2014-05-06 Bio-Rad Laboratories, Inc. Instrument for independent electrotransfer in multiple cassettes
US20130168250A1 (en) * 2010-09-16 2013-07-04 Advanced Liquid Logic Inc Droplet Actuator Systems, Devices and Methods
WO2012054588A2 (en) * 2010-10-22 2012-04-26 T2 Biosystems, Inc. Conduit-containing devices and methods for analyte processing and detection
JP6040940B2 (en) 2010-12-16 2016-12-07 ベーリンガー インゲルハイム マイクロパーツ ゲゼルシャフト ミット ベシュレンクテル ハフツングBoehringer Ingelheim microParts GmbH Method for filling cavities, especially blisters in blister packaging, with liquid and semi-finished product used in such a method
DK2681550T3 (en) * 2011-03-01 2016-09-12 Sophion Bioscience As Hand-held device for electrophysiological analysis
US20130178068A1 (en) 2012-01-10 2013-07-11 Taiwan Semiconductor Manufacturing Co., Ltd. Dual damascene process and apparatus
US9245105B1 (en) 2012-02-22 2016-01-26 Google Inc. Verification of remote job state for access control
US9338726B2 (en) 2012-10-15 2016-05-10 Qualcomm Incorporated Cooperative data mules
US9135183B2 (en) 2013-03-13 2015-09-15 Samsung Electronics Co., Ltd. Multi-threaded memory management
CA2906920C (en) 2013-03-15 2021-01-05 Armour Technologies, Inc. Medical device curving apparatus, system, and method of use
US9910104B2 (en) 2015-01-23 2018-03-06 Lockheed Martin Corporation DNV magnetic field detector
US9306653B2 (en) 2014-06-02 2016-04-05 Qualcomm Incorporated Enhanced opportunistic mobile receive diversity for dual-SIM dual-active mobile device
EP3218108B1 (en) 2014-11-11 2020-09-02 Genmark Diagnostics Inc. Fluid sample processing cartridge and use thereof

Patent Citations (657)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641909A (en) 1969-07-03 1972-02-15 Polaroid Corp System for rupturing a pod containing processing fluid for photographic apparatus
US3687051A (en) 1969-07-03 1972-08-29 Polaroid Corp System for rupturing pod containing processing fluid for photographic material
US3776425A (en) 1969-07-03 1973-12-04 Polaroid Corp System for rupturing pod containing processing fluid for photographic material
US3820149A (en) 1969-07-03 1974-06-25 Polaroid Corp System for rupturing pod containing processing fluid for photographic material
US4007010A (en) 1974-07-03 1977-02-08 Woodbridge Iii Richard G Blister plane apparatus for testing samples of fluid
US4065263A (en) 1976-04-02 1977-12-27 Woodbridge Iii Richard G Analytical test strip apparatus
USD253126S (en) 1977-04-18 1979-10-09 American Home Products Corp. Necropsy board for small animals
US4182447A (en) 1977-07-27 1980-01-08 Ira Kay Device for storing, transporting and mixing reactive ingredients
USD268130S (en) 1980-06-27 1983-03-01 Easton Harlan J Tray for veterinary supplies and equipment
US4469863A (en) 1980-11-12 1984-09-04 Ts O Paul O P Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
US4429792A (en) 1981-09-11 1984-02-07 Medication Services, Inc. Medication-dispensing card
US4526320A (en) 1982-05-15 1985-07-02 Globol-Werk Gmbh Apparatus for vaporizing insecticides, perfumes and/or other volatile agents
USD287760S (en) 1984-03-05 1987-01-13 Discko Jr John J Dental tray
US5034506A (en) 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US5235033A (en) 1985-03-15 1993-08-10 Anti-Gene Development Group Alpha-morpholino ribonucleoside derivatives and polymers thereof
US4844251A (en) 1986-08-12 1989-07-04 L'oreal Container means for separately storing at least two products to be brought into contact at the time of use
US4739903A (en) 1986-10-01 1988-04-26 Fibre Glass-Evercoat Company, Inc. Dispensing case assembly
US5714380A (en) 1986-10-23 1998-02-03 Amoco Corporation Closed vessel for isolating target molecules and for performing amplification
US4978502A (en) 1987-01-05 1990-12-18 Dole Associates, Inc. Immunoassay or diagnostic device and method of manufacture
US4859603A (en) 1987-01-05 1989-08-22 Dole Associates, Inc. Personal diagnostic kit
US4769333A (en) 1987-01-05 1988-09-06 Dole Associates, Inc. Personal diagnostic kit
US4887455A (en) 1987-04-06 1989-12-19 Cogent Limited Gas sensor
US5216141A (en) 1988-06-06 1993-06-01 Benner Steven A Oligonucleotide analogs containing sulfur linkages
USD327363S (en) 1988-09-19 1992-06-30 Farb M Daniel Portable ophthalmic instrument case
US5512439A (en) 1988-11-21 1996-04-30 Dynal As Oligonucleotide-linked magnetic particles and uses thereof
US6645758B1 (en) 1989-02-03 2003-11-11 Johnson & Johnson Clinical Diagnostics, Inc. Containment cuvette for PCR and method of use
US5229297A (en) 1989-02-03 1993-07-20 Eastman Kodak Company Containment cuvette for PCR and method of use
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
US5460780A (en) 1989-06-12 1995-10-24 Devaney, Jr.; Mark J. Temperature control device and reaction vessel
US5089233A (en) 1989-06-12 1992-02-18 Eastman Kodak Company Processing apparatus for a chemical reaction pack
US5098660A (en) 1990-01-08 1992-03-24 Eastman Kodak Company Transfer apparatus for chemical reaction pack
US5386023A (en) 1990-07-27 1995-01-31 Isis Pharmaceuticals Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
US5602240A (en) 1990-07-27 1997-02-11 Ciba Geigy Ag. Backbone modified oligonucleotide analogs
US5154888A (en) 1990-10-25 1992-10-13 Eastman Kodak Company Automatic sealing closure means for closing off a passage in a flexible cuvette
US5254479A (en) 1991-12-19 1993-10-19 Eastman Kodak Company Methods for preventing air injection into a detection chamber supplied with injected liquid
US5644048A (en) 1992-01-10 1997-07-01 Isis Pharmaceuticals, Inc. Process for preparing phosphorothioate oligonucleotides
US5468366A (en) 1992-01-15 1995-11-21 Andcare, Inc. Colloidal-gold electrosensor measuring device
USD351996S (en) 1992-06-23 1994-11-01 Multi-Comp, Inc. Dispensing container for pharmaceutical medication
EP0583833A2 (en) 1992-08-17 1994-02-23 Eastman Kodak Company Flexible extraction device
US5290518A (en) 1992-08-17 1994-03-01 Eastman Kodak Company Flexible extraction device with burstable sidewall
US5820826A (en) 1992-09-03 1998-10-13 Boehringer Mannheim Company Casing means for analytical test apparatus
US5288463A (en) 1992-10-23 1994-02-22 Eastman Kodak Company Positive flow control in an unvented container
US5422271A (en) 1992-11-20 1995-06-06 Eastman Kodak Company Nucleic acid material amplification and detection without washing
US5652149A (en) 1992-12-08 1997-07-29 Westinghouse Electric Corporation Mixing apparatus & method for an optical agglutination assay device
US5399486A (en) 1993-02-18 1995-03-21 Biocircuits Corporation Disposable unit in diagnostic assays
USD350478S (en) 1993-03-30 1994-09-13 Fuller Kathryn O Weekly pill organizer calendar
US5449096A (en) 1993-04-10 1995-09-12 Hilti Aktiengesellschaft Piston for a dispensing tool
US5374395A (en) 1993-10-14 1994-12-20 Amoco Corporation Diagnostics instrument
US5849486A (en) 1993-11-01 1998-12-15 Nanogen, Inc. Methods for hybridization analysis utilizing electrically controlled hybridization
US5824473A (en) 1993-12-10 1998-10-20 California Institute Of Technology Nucleic acid mediated electron transfer
US5591578A (en) 1993-12-10 1997-01-07 California Institute Of Technology Nucleic acid mediated electron transfer
US5705348A (en) 1993-12-10 1998-01-06 California Institute Of Technology Nucleic acid mediated electron transfer
US5637684A (en) 1994-02-23 1997-06-10 Isis Pharmaceuticals, Inc. Phosphoramidate and phosphorothioamidate oligomeric compounds
US5807701A (en) 1994-06-09 1998-09-15 Aromascan Plc Method and apparatus for detecting microorganisms
US6180064B1 (en) 1994-06-23 2001-01-30 Osmetech Plc Semiconducting organic polymer gas sensor
US5882497A (en) 1994-06-23 1999-03-16 Aromascan Plc Semiconducting organic polymers for gas sensors
US5692644A (en) 1994-07-25 1997-12-02 L'oreal Container for storing at least two products, mixing these products, and dispensing the mixture thus obtained
US5681702A (en) 1994-08-30 1997-10-28 Chiron Corporation Reduction of nonspecific hybridization by using novel base-pairing schemes
US5898071A (en) 1994-09-20 1999-04-27 Whitehead Institute For Biomedical Research DNA purification and isolation using magnetic particles
US5705628A (en) 1994-09-20 1998-01-06 Whitehead Institute For Biomedical Research DNA purification and isolation using magnetic particles
US5529188A (en) 1994-09-28 1996-06-25 Becton Dickinson And Company Child resistant carded type blister folder
US6033601A (en) 1994-12-14 2000-03-07 Aromascan Plc Semiconducting organic polymers
US6706498B2 (en) 1995-02-14 2004-03-16 Bio101, Inc. Method for isolating DNA
US6235501B1 (en) 1995-02-14 2001-05-22 Bio101, Inc. Method for isolation DNA
US6192351B1 (en) 1995-02-24 2001-02-20 Osmetech Plc Fuzzy neural networks
US6227809B1 (en) 1995-03-09 2001-05-08 University Of Washington Method for making micropumps
US5876187A (en) 1995-03-09 1999-03-02 University Of Washington Micropumps with fixed valves
US6265155B1 (en) 1995-06-07 2001-07-24 California Institute Of Technology Metallic solid supports modified with nucleic acids
US6255477B1 (en) 1995-06-08 2001-07-03 Roche Diagnostics Gmbh Particles having a magnetic core and outer glass layer for separating biological material
US7371830B2 (en) 1995-06-08 2008-05-13 Roche Diagnostics Gmbh Method for separating biological material from a fluid using magnetic particles
US8129118B2 (en) 1995-06-08 2012-03-06 Roche Diagnostics Gmbh Magnetic glass particles, method for their preparation and uses thereof
US6454945B1 (en) 1995-06-16 2002-09-24 University Of Washington Microfabricated devices and methods
US5932100A (en) 1995-06-16 1999-08-03 University Of Washington Microfabricated differential extraction device and method
US6387290B1 (en) 1995-06-16 2002-05-14 University Of Washington Tangential flow planar microfabricated fluid filter
US7119194B2 (en) 1995-07-07 2006-10-10 Toyo Boseki Kabushiki Kaisha Nucleic acid-bondable magnetic carrier and method for isolating nucleic acid using the same
US5873990A (en) 1995-08-22 1999-02-23 Andcare, Inc. Handheld electromonitor device
US5770365A (en) 1995-08-25 1998-06-23 Tm Technologies, Inc. Nucleic acid capture moieties
US5726751A (en) 1995-09-27 1998-03-10 University Of Washington Silicon microchannel optical flow cytometer
US20020068357A1 (en) 1995-09-28 2002-06-06 Mathies Richard A. Miniaturized integrated nucleic acid processing and analysis device and method
US6236951B1 (en) 1995-11-16 2001-05-22 Osmetech Plc Sensor interrogation
US5851536A (en) 1995-11-22 1998-12-22 University Of Washington Therapeutic delivery using compounds self-assembled into high axial ratio microstructures
US5674653A (en) 1995-12-05 1997-10-07 Eastman Kodak Company Test pouch
US5593804A (en) 1995-12-05 1997-01-14 Eastman Kodak Company Test pouch
US5747349A (en) 1996-03-20 1998-05-05 University Of Washington Fluorescent reporter beads for fluid analysis
US6171865B1 (en) 1996-03-29 2001-01-09 University Of Washington Simultaneous analyte determination and reference balancing in reference T-sensor devices
US6541213B1 (en) 1996-03-29 2003-04-01 University Of Washington Microscale diffusion immunoassay
US6582963B1 (en) 1996-03-29 2003-06-24 University Of Washington Simultaneous analyte determination and reference balancing in reference T-sensor devices
US7271007B2 (en) 1996-03-29 2007-09-18 University Of Washington Microscale diffusion immunoassay
US5716852A (en) 1996-03-29 1998-02-10 University Of Washington Microfabricated diffusion-based chemical sensor
US5972710A (en) 1996-03-29 1999-10-26 University Of Washington Microfabricated diffusion-based chemical sensor
US6399023B1 (en) 1996-04-16 2002-06-04 Caliper Technologies Corp. Analytical system and method
US5726404A (en) 1996-05-31 1998-03-10 University Of Washington Valveless liquid microswitch
US5971158A (en) 1996-06-14 1999-10-26 University Of Washington Absorption-enhanced differential extraction device
US6695147B1 (en) 1996-06-14 2004-02-24 University Of Washington Absorption-enhanced differential extraction device
US6432720B2 (en) 1996-08-02 2002-08-13 Caliper Technologies Corp. Analytical system and method
US6071478A (en) 1996-08-02 2000-06-06 Caliper Technologies Corp. Analytical system and method
US6503757B1 (en) 1996-08-02 2003-01-07 Caliper Technologies Corp. Analytical system and method
US6399025B1 (en) 1996-08-02 2002-06-04 Caliper Technologies Corp. Analytical system and method
US5955028A (en) 1996-08-02 1999-09-21 Caliper Technologies Corp. Analytical system and method
US6039897A (en) 1996-08-28 2000-03-21 University Of Washington Multiple patterned structures on a single substrate fabricated by elastomeric micro-molding techniques
US5748827A (en) 1996-10-23 1998-05-05 University Of Washington Two-stage kinematic mount
US6110354A (en) 1996-11-01 2000-08-29 University Of Washington Microband electrode arrays
US6790341B1 (en) 1996-11-01 2004-09-14 University Of Washington Microband electrode arrays
US6096273A (en) 1996-11-05 2000-08-01 Clinical Micro Sensors Electrodes linked via conductive oligomers to nucleic acids
US7160678B1 (en) 1996-11-05 2007-01-09 Clinical Micro Sensors, Inc. Compositions for the electronic detection of analytes utilizing monolayers
US6221583B1 (en) 1996-11-05 2001-04-24 Clinical Micro Sensors, Inc. Methods of detecting nucleic acids using electrodes
US6495323B1 (en) 1996-11-05 2002-12-17 Clinical Micro Sensors, Inc. AC methods for the detection of nucleic acids
US7014992B1 (en) 1996-11-05 2006-03-21 Clinical Micro Sensors, Inc. Conductive oligomers attached to electrodes and nucleoside analogs
US7125668B2 (en) 1996-11-05 2006-10-24 Clinical Micro Sensors, Inc. Electrodes linked via conductive oligomers to nucleic acids
US6479240B1 (en) 1996-11-05 2002-11-12 Clinical Micro Sensors, Inc. Electrodes linked via conductive oligomers to nucleic acids
US7384749B2 (en) 1996-11-05 2008-06-10 Clinical Micro Sensors, Inc. Electrodes linked via conductive oligomers to nucleic acids
US7045285B1 (en) 1996-11-05 2006-05-16 Clinical Micro Sensors, Inc. Electronic transfer moieties attached to peptide nucleic acids
US7056669B2 (en) 1996-11-05 2006-06-06 Clinical Micro Sensors, Inc. AC methods for the detection of nucleic acids
US7393645B2 (en) 1996-11-05 2008-07-01 Clinical Micro Sensors, Inc. Compositions for the electronic detection of analytes utilizing monolayers
US6977151B2 (en) 1996-11-05 2005-12-20 Clinical Micro Sensors, Inc. Electrodes linked via conductive oligomers to nucleic acids
US7381533B2 (en) 1996-11-05 2008-06-03 Clinical Micro Sensors, Inc. Electrodes linked via oligomers to nucleic acids
US6090933A (en) 1996-11-05 2000-07-18 Clinical Micro Sensors, Inc. Methods of attaching conductive oligomers to electrodes
US6180114B1 (en) 1996-11-21 2001-01-30 University Of Washington Therapeutic delivery using compounds self-assembled into high axial ratio microstructures
US6190858B1 (en) 1997-01-02 2001-02-20 Osmetech Plc Detection of conditions by analysis of gases or vapors
US6376232B1 (en) 1997-03-06 2002-04-23 Osmetech Plc Microorganism analysis means
US6232062B1 (en) 1997-03-07 2001-05-15 Clinical Micro Sensors, Inc. AC methods for the detection of nucleic acids
US7381525B1 (en) 1997-03-07 2008-06-03 Clinical Micro Sensors, Inc. AC/DC voltage apparatus for detection of nucleic acids
US6230884B1 (en) 1997-03-12 2001-05-15 Fredrick Michael Coory Discharge cap with releasable tablet basket
US7169358B2 (en) 1997-03-18 2007-01-30 Henkens Robert W Electrochemical detection of nucleic acid sequences
US6391558B1 (en) 1997-03-18 2002-05-21 Andcare, Inc. Electrochemical detection of nucleic acid sequences
US6159739A (en) 1997-03-26 2000-12-12 University Of Washington Device and method for 3-dimensional alignment of particles in microfabricated flow channels
US5948684A (en) 1997-03-31 1999-09-07 University Of Washington Simultaneous analyte determination and reference balancing in reference T-sensor devices
US6391622B1 (en) 1997-04-04 2002-05-21 Caliper Technologies Corp. Closed-loop biochemical analyzers
US6403338B1 (en) 1997-04-04 2002-06-11 Mountain View Microfluidic systems and methods of genotyping
EP0870541A2 (en) 1997-04-11 1998-10-14 Eastman Kodak Company Integrated ceramic micro-chemical plant
US6660480B2 (en) 1997-04-28 2003-12-09 Ut-Battelle, Llc Method for analyzing nucleic acids by means of a substrate having a microchannel structure containing immobilized nucleic acid probes
US7582419B2 (en) 1997-06-12 2009-09-01 Osmetech Technology Inc. Detection of analytes using reorganization energy
US6013170A (en) 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
US7560237B2 (en) 1997-06-12 2009-07-14 Osmetech Technology Inc. Electronics method for the detection of analytes
US7759073B2 (en) 1997-06-12 2010-07-20 Osmetech Technology Inc. Electronic methods for the detection of analytes
US6248229B1 (en) 1997-06-12 2001-06-19 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
US7566534B2 (en) 1997-06-12 2009-07-28 Osmetech Technology Inc. Detection of analytes using reorganization energy
US7514228B2 (en) 1997-06-12 2009-04-07 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
US7018523B2 (en) 1997-06-12 2006-03-28 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
US7595153B2 (en) 1997-06-12 2009-09-29 Osmetech Technology Inc. Detection of analytes using reorganization energy
US7267939B2 (en) 1997-06-12 2007-09-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
US6013459A (en) 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
US8114661B2 (en) 1997-06-12 2012-02-14 Osmetech Technology, Inc. Electronic methods for the detection of analytes
US7713711B2 (en) 1997-06-12 2010-05-11 Osmetech Technology Inc. Electronic methods for the detection of analytes
US7579145B2 (en) 1997-06-12 2009-08-25 Osmetech Technology Inc. Detection of analytes using reorganization energy
US7601507B2 (en) 1997-06-12 2009-10-13 Osmetech Technology Inc. Electronic methods for the detection of analytes
US5974867A (en) 1997-06-13 1999-11-02 University Of Washington Method for determining concentration of a laminar sample stream
US6134950A (en) 1997-06-13 2000-10-24 University Of Washington Method for determining concentration of a laminar sample stream
US6268136B1 (en) 1997-06-16 2001-07-31 Exact Science Corporation Methods for stool sample preparation
US6406857B1 (en) 1997-06-16 2002-06-18 Exact Sciences Corporation Methods for stool sample preparation
US6431016B1 (en) 1997-07-05 2002-08-13 Osmetech Plc Apparatus and methods for gas sampling
US6065641A (en) 1997-07-16 2000-05-23 Laboratorios Inibsa, S.A. Cartridge containing two liquids
US6426230B1 (en) 1997-08-01 2002-07-30 Qualigen, Inc. Disposable diagnostic device and method
US6300138B1 (en) 1997-08-01 2001-10-09 Qualigen, Inc. Methods for conducting tests
US6893879B2 (en) 1997-08-13 2005-05-17 Cepheid Method for separating analyte from a sample
US6136272A (en) 1997-09-26 2000-10-24 University Of Washington Device for rapidly joining and splitting fluid layers
US6277641B1 (en) 1997-09-26 2001-08-21 University Of Washington Methods for analyzing the presence and concentration of multiple analytes using a diffusion-based chemical sensor
US6221677B1 (en) 1997-09-26 2001-04-24 University Of Washington Simultaneous particle separation and chemical reaction
US6007775A (en) 1997-09-26 1999-12-28 University Of Washington Multiple analyte diffusion based chemical sensor
US6297061B1 (en) 1997-09-26 2001-10-02 University Of Washington Simultaneous particle separation and chemical reaction
US6562568B1 (en) 1997-10-01 2003-05-13 Roche Diagnostics Gmbh Method, kit and apparatus comprising magnetic glass particles for the isolation of biomolecules
US5842787A (en) 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
US5957579A (en) 1997-10-09 1999-09-28 Caliper Technologies Corp. Microfluidic systems incorporating varied channel dimensions
US6098795A (en) 1997-10-14 2000-08-08 Mollstam; Bo Device for adding a component to a package
US6914137B2 (en) 1997-12-06 2005-07-05 Dna Research Innovations Limited Isolation of nucleic acids
US6440725B1 (en) 1997-12-24 2002-08-27 Cepheid Integrated fluid manipulation cartridge
US7569346B2 (en) 1997-12-24 2009-08-04 Cepheid Method for separating analyte from a sample
US6857449B1 (en) 1998-01-20 2005-02-22 Caliper Life Sciences, Inc. Multi-layer microfluidic devices
US6494230B2 (en) 1998-01-20 2002-12-17 Caliper Technologies Corp. Multi-layer microfluidic devices
US6321791B1 (en) 1998-01-20 2001-11-27 Caliper Technologies Corp. Multi-layer microfluidic devices
US6648015B1 (en) 1998-01-20 2003-11-18 Caliper Technologies Corp. Multi-layer microfluidic devices
US6167910B1 (en) 1998-01-20 2001-01-02 Caliper Technologies Corp. Multi-layer microfluidic devices
US6063573A (en) 1998-01-27 2000-05-16 Clinical Micro Sensors, Inc. Cycling probe technology using electron transfer detection
US6686150B1 (en) 1998-01-27 2004-02-03 Clinical Micro Sensors, Inc. Amplification of nucleic acids with electronic detection
US7090804B2 (en) 1998-01-27 2006-08-15 Clinical Mirco Sensors, Inc. Amplification of nucleic acids with electronic detection
US20020006643A1 (en) 1998-01-27 2002-01-17 Jon Faiz Kayyem Amplification of nucleic acids with electronic detection
US6979424B2 (en) 1998-03-17 2005-12-27 Cepheid Integrated sample analysis device
US6655010B1 (en) 1998-03-20 2003-12-02 Osmetech Plc Method for batch manufacturing sensor units
US6600026B1 (en) 1998-05-06 2003-07-29 Clinical Micro Sensors, Inc. Electronic methods for the detection of analytes utilizing monolayers
US6123798A (en) 1998-05-06 2000-09-26 Caliper Technologies Corp. Methods of fabricating polymeric structures incorporating microscale fluidic elements
US6656431B2 (en) 1998-05-18 2003-12-02 University Of Washington Sample analysis instrument
US6852284B1 (en) 1998-05-18 2005-02-08 University Of Washington Liquid analysis cartridge
US7226562B2 (en) 1998-05-18 2007-06-05 University Of Washington Liquid analysis cartridge
US6712925B1 (en) 1998-05-18 2004-03-30 University Of Washington Method of making a liquid analysis cartridge
US6830729B1 (en) 1998-05-18 2004-12-14 University Of Washington Sample analysis instrument
US6537501B1 (en) 1998-05-18 2003-03-25 University Of Washington Disposable hematology cartridge
US6576194B1 (en) 1998-05-18 2003-06-10 University Of Washington Sheath flow assembly
US6761816B1 (en) 1998-06-23 2004-07-13 Clinical Micro Systems, Inc. Printed circuit boards with monolayers and capture ligands
US7087148B1 (en) 1998-06-23 2006-08-08 Clinical Micro Sensors, Inc. Binding acceleration techniques for the detection of analytes
US20050003399A1 (en) 1998-06-23 2005-01-06 Gary Blackburn Binding acceleration techniques for the detection of analytes
US7655129B2 (en) 1998-06-23 2010-02-02 Osmetech Technology Inc. Binding acceleration techniques for the detection of analytes
US6290839B1 (en) 1998-06-23 2001-09-18 Clinical Micro Sensors, Inc. Systems for electrophoretic transport and detection of analytes
US6264825B1 (en) 1998-06-23 2001-07-24 Clinical Micro Sensors, Inc. Binding acceleration techniques for the detection of analytes
US6366924B1 (en) 1998-07-27 2002-04-02 Caliper Technologies Corp. Distributed database for analytical instruments
US7155344B1 (en) 1998-07-27 2006-12-26 Caliper Life Sciences, Inc. Distributed database for analytical instruments
US6647397B2 (en) 1998-07-27 2003-11-11 Caliper Technologies Corp. Distributed database for analytical instruments
US7343248B2 (en) 1998-07-27 2008-03-11 Caliper Life Sciences Distributed database for analytical instruments
US6627412B1 (en) 1998-08-21 2003-09-30 Osmetech Plc Method for detecting microorganisms
US6740518B1 (en) 1998-09-17 2004-05-25 Clinical Micro Sensors, Inc. Signal detection techniques for the detection of analytes
US6482306B1 (en) 1998-09-22 2002-11-19 University Of Washington Meso- and microfluidic continuous flow and stopped flow electroösmotic mixer
US6067157A (en) 1998-10-09 2000-05-23 University Of Washington Dual large angle light scattering detection
US6404493B1 (en) 1998-10-09 2002-06-11 University Of Washington Dual large angle light scattering detection
US6591852B1 (en) 1998-10-13 2003-07-15 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
US6003728A (en) 1998-10-22 1999-12-21 Aptargroup, Inc. Dispensing structure with an openable member for separating two products
US8501921B2 (en) 1998-10-27 2013-08-06 Osmetech Technology, Inc. Detection of target analytes using particles and electrodes
US8012743B2 (en) 1998-10-27 2011-09-06 Osmetech Technology Inc. Detection of target analytes using particles and electrodes
US6541617B1 (en) 1998-10-27 2003-04-01 Clinical Micro Sensors, Inc. Detection of target analytes using particles and electrodes
US6488895B1 (en) 1998-10-29 2002-12-03 Caliper Technologies Corp. Multiplexed microfluidic devices, systems, and methods
US5973138A (en) 1998-10-30 1999-10-26 Becton Dickinson And Company Method for purification and manipulation of nucleic acids using paramagnetic particles
US6433160B1 (en) 1998-10-30 2002-08-13 Becton, Dickinson And Company Method for purification and manipulation of nucleic acids using paramagnetic particles
US6919444B2 (en) 1998-11-30 2005-07-19 Roche Diagnostics Gmbh Magnetic particles for purifying nucleic acids
US6091502A (en) 1998-12-23 2000-07-18 Micronics, Inc. Device and method for performing spectral measurements in flow cells with spatial resolution
US7914994B2 (en) 1998-12-24 2011-03-29 Cepheid Method for separating an analyte from a sample
US8247176B2 (en) 1998-12-24 2012-08-21 Cepheid Method for separating an analyte from a sample
US6887693B2 (en) 1998-12-24 2005-05-03 Cepheid Device and method for lysing cells, spores, or microorganisms
US6833267B1 (en) 1998-12-30 2004-12-21 Clinical Micro Sensors, Inc. Tissue collection devices containing biosensors
US6432723B1 (en) 1999-01-22 2002-08-13 Clinical Micro Sensors, Inc. Biosensors utilizing ligand induced conformation changes
US7943030B2 (en) 1999-01-25 2011-05-17 Advanced Liquid Logic, Inc. Actuators for microfluidics without moving parts
US6565727B1 (en) 1999-01-25 2003-05-20 Nanolytics, Inc. Actuators for microfluidics without moving parts
US20110209998A1 (en) 1999-01-25 2011-09-01 Advanced Liquid Logic, Inc. Droplet Actuator and Methods
US7255780B2 (en) 1999-01-25 2007-08-14 Nanolytics, Inc. Method of using actuators for microfluidics without moving parts
US6451606B1 (en) 1999-01-30 2002-09-17 Fresenius Medical Care Deutschland Gmbh Receptacle unit for solutions, in particular solutions for calibration of sensors for measuring physiologically relevant parameters
US20070098600A1 (en) 1999-04-21 2007-05-03 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
US9557295B2 (en) 1999-04-21 2017-01-31 Osmetech Technology, Inc. Use of microfluidic systems in the electrochemical detection of target analytes
US7534331B2 (en) 1999-04-21 2009-05-19 Osmetech Technology Inc. Use of microfluidic systems in the electrochemical detection of target analytes
US6942771B1 (en) 1999-04-21 2005-09-13 Clinical Micro Sensors, Inc. Microfluidic systems in the electrochemical detection of target analytes
US6881541B2 (en) 1999-05-28 2005-04-19 Cepheid Method for analyzing a fluid sample
US8168442B2 (en) 1999-05-28 2012-05-01 Cepheid Cartridge for conducting a chemical reaction
US7449096B2 (en) 1999-06-22 2008-11-11 Manfred Berndt Apparatus for the operation of a microfluidic device
US6811668B1 (en) 1999-06-22 2004-11-02 Caliper Life Sciences, Inc. Apparatus for the operation of a microfluidic device
US6878540B2 (en) 1999-06-25 2005-04-12 Cepheid Device for lysing cells, spores, or microorganisms
US6664104B2 (en) 1999-06-25 2003-12-16 Cepheid Device incorporating a microfluidic chip for separating analyte from a sample
US7935481B1 (en) 1999-07-26 2011-05-03 Osmetech Technology Inc. Sequence determination of nucleic acids using electronic detection
US6524456B1 (en) 1999-08-12 2003-02-25 Ut-Battelle, Llc Microfluidic devices for the controlled manipulation of small volumes
US7238268B2 (en) 1999-08-12 2007-07-03 Ut-Battelle, Llc Microfluidic devices for the controlled manipulation of small volumes
US6495104B1 (en) 1999-08-19 2002-12-17 Caliper Technologies Corp. Indicator components for microfluidic systems
US6743399B1 (en) 1999-10-08 2004-06-01 Micronics, Inc. Pumpless microfluidics
US6596483B1 (en) 1999-11-12 2003-07-22 Motorola, Inc. System and method for detecting molecules using an active pixel sensor
US6960467B2 (en) 1999-11-12 2005-11-01 Clinical Micro Sensors, Inc. Biochannel assay for hybridization with biomaterial
US6361958B1 (en) 1999-11-12 2002-03-26 Motorola, Inc. Biochannel assay for hybridization with biomaterial
US6875619B2 (en) 1999-11-12 2005-04-05 Motorola, Inc. Microfluidic devices comprising biochannels
US6642046B1 (en) 1999-12-09 2003-11-04 Motorola, Inc. Method and apparatus for performing biological reactions on a substrate surface
US6518024B2 (en) 1999-12-13 2003-02-11 Motorola, Inc. Electrochemical detection of single base extension
US6415821B2 (en) 1999-12-15 2002-07-09 University Of Washington Magnetically actuated fluid handling devices for microfluidic applications
US6408884B1 (en) 1999-12-15 2002-06-25 University Of Washington Magnetically actuated fluid handling devices for microfluidic applications
US6431476B1 (en) 1999-12-21 2002-08-13 Cepheid Apparatus and method for rapid ultrasonic disruption of cells or viruses
US7312087B2 (en) 2000-01-11 2007-12-25 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
US7172897B2 (en) 2000-01-11 2007-02-06 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
US20040053290A1 (en) 2000-01-11 2004-03-18 Terbrueggen Robert Henry Devices and methods for biochip multiplexing
US6443307B1 (en) 2000-01-25 2002-09-03 Michael D. Burridge Medication dispenser with an internal ejector
US20030034271A1 (en) 2000-01-25 2003-02-20 Burridge Michael D. Internal ejector punch for blister-pack type containers
US6824669B1 (en) 2000-02-17 2004-11-30 Motorola, Inc. Protein and peptide sensors using electrical detection methods
US20030038040A1 (en) 2000-03-01 2003-02-27 Mathias Bertl Device for storing and dispensing a free-flowing substance
US20030048631A1 (en) 2000-03-01 2003-03-13 Jacques Ladyjensky Chemiluminescent lighting element
US6488896B2 (en) 2000-03-14 2002-12-03 Micronics, Inc. Microfluidic analysis cartridge
US6881312B2 (en) 2000-03-27 2005-04-19 Caliper Life Sciences, Inc. Ultra high throughput microfluidic analytical systems and methods
US6409832B2 (en) 2000-03-31 2002-06-25 Micronics, Inc. Protein crystallization in microfluidic structures
US6753143B2 (en) 2000-05-01 2004-06-22 Clinical Micro Sensors, Inc. Target analyte detection using asymmetrical self-assembled monolayers
US6557427B2 (en) 2000-05-24 2003-05-06 Micronics, Inc. Capillaries for fluid movement within microfluidic channels
US6431212B1 (en) 2000-05-24 2002-08-13 Jon W. Hayenga Valve for use in microfluidic structures
US6602400B1 (en) 2000-06-15 2003-08-05 Motorola, Inc. Method for enhanced bio-conjugation events
US20030197139A1 (en) 2000-06-23 2003-10-23 Micronics, Inc. Valve for use in microfluidic structures
US6581899B2 (en) 2000-06-23 2003-06-24 Micronics, Inc. Valve for use in microfluidic structures
US6773566B2 (en) 2000-08-31 2004-08-10 Nanolytics, Inc. Electrostatic actuators for microfluidics and methods for using same
US7011791B2 (en) 2000-09-18 2006-03-14 University Of Washington Microfluidic devices for rotational manipulation of the fluidic interface between multiple flow streams
US20020066677A1 (en) 2000-12-01 2002-06-06 Brett Moscovitz Device for storing and dispensing a substance by mating with a container and associated methods
US7910294B2 (en) 2000-12-05 2011-03-22 Norchip A/S Ligand detection method
US7670559B2 (en) 2001-02-15 2010-03-02 Caliper Life Sciences, Inc. Microfluidic systems with enhanced detection systems
US6443179B1 (en) 2001-02-21 2002-09-03 Sandia Corporation Packaging of electro-microfluidic devices
US20040037739A1 (en) 2001-03-09 2004-02-26 Mcneely Michael Method and system for microfluidic interfacing to arrays
US7270786B2 (en) 2001-03-28 2007-09-18 Handylab, Inc. Methods and systems for processing microfluidic samples of particle containing fluids
US20120022695A1 (en) 2001-03-28 2012-01-26 Handylab, Inc. Methods and systems for control of microfluidic devices
US7323140B2 (en) 2001-03-28 2008-01-29 Handylab, Inc. Moving microdroplets in a microfluidic device
US7192557B2 (en) 2001-03-28 2007-03-20 Handylab, Inc. Methods and systems for releasing intracellular material from cells within microfluidic samples of fluids
US7010391B2 (en) 2001-03-28 2006-03-07 Handylab, Inc. Methods and systems for control of microfluidic devices
US7987022B2 (en) 2001-03-28 2011-07-26 Handylab, Inc. Methods and systems for control of microfluidic devices
US8273308B2 (en) 2001-03-28 2012-09-25 Handylab, Inc. Moving microdroplets in a microfluidic device
US20040229378A1 (en) 2001-04-03 2004-11-18 Micronics, Inc. Well-plate microfluidics
US20050201903A1 (en) 2001-04-03 2005-09-15 Micronics, Inc. Microfluidic device for concentrating particles in a concentrating solution
US20050205816A1 (en) 2001-04-03 2005-09-22 Micronics, Inc. Pneumatic valve interface for use in microfluidic structures
US6742661B1 (en) 2001-04-03 2004-06-01 Micronics, Inc. Well-plate microfluidics
US6674525B2 (en) 2001-04-03 2004-01-06 Micronics, Inc. Split focusing cytometer
US6960437B2 (en) 2001-04-06 2005-11-01 California Institute Of Technology Nucleic acid amplification utilizing microfluidic devices
US7833708B2 (en) 2001-04-06 2010-11-16 California Institute Of Technology Nucleic acid amplification using microfluidic devices
US20030025129A1 (en) 2001-07-24 2003-02-06 Lg.Electronics Inc. Handling and delivering fluid through a microchannel in an elastic substrate by progressively squeezing the microchannel along its length
US6575188B2 (en) 2001-07-26 2003-06-10 Handylab, Inc. Methods and systems for fluid control in microfluidic devices
US6951759B2 (en) 2001-08-17 2005-10-04 Osmetech Plc Detection of bacterial vaginosis
US6739531B2 (en) 2001-10-04 2004-05-25 Cepheid Apparatus and method for rapid disruption of cells or viruses
US7141429B2 (en) 2001-10-09 2006-11-28 University Of Washington Use of liquid junction potentials for electrophoresis without applied voltage in a microfluidic channel
US6783647B2 (en) 2001-10-19 2004-08-31 Ut-Battelle, Llc Microfluidic systems and methods of transport and lysis of cells and analysis of cell lysate
US7419575B2 (en) 2001-10-19 2008-09-02 Ut-Battelle, Llc Microfluidic systems and methods for transport and lysis of cells and analysis of cell lysate
US6967489B2 (en) 2001-11-13 2005-11-22 Caliper Life Sciences, Inc. Method and apparatus for controllably effecting samples using two signals
US7163612B2 (en) 2001-11-26 2007-01-16 Keck Graduate Institute Method, apparatus and article for microfluidic control via electrowetting, for chemical, biochemical and biological assays and the like
US7208271B2 (en) 2001-11-28 2007-04-24 Applera Corporation Compositions and methods of selective nucleic acid isolation
US7258837B2 (en) 2001-12-05 2007-08-21 University Of Washington Microfluidic device and surface decoration process for solid phase affinity binding assays
US7473397B2 (en) 2001-12-13 2009-01-06 The Technology Partnership Plc Device for chemical or biochemical analysis
US7867757B2 (en) 2001-12-28 2011-01-11 Norchip As Fluid manipulation in a microfabricated reaction chamber systems
US20050064423A1 (en) 2002-01-08 2005-03-24 Toshiro Higuchi Pcr method by electrostatic transportation, hybridization method for electrostatic transportation and devices therefor
US7056475B2 (en) 2002-01-30 2006-06-06 Agilent Technologies, Inc. Fluidically isolated pumping and metered fluid delivery system and methods
US7223371B2 (en) 2002-03-14 2007-05-29 Micronics, Inc. Microfluidic channel network device
US7416791B1 (en) 2002-06-11 2008-08-26 University Of Washington Osmium complexes and related organic light-emitting devices
US7201881B2 (en) 2002-07-26 2007-04-10 Applera Corporation Actuator for deformable valves in a microfluidic device, and method
US20050233440A1 (en) 2002-09-17 2005-10-20 Stmicroelectronics S.R.L. Apparatus for biochemical analysis
US20130118901A1 (en) 2002-09-24 2013-05-16 Duke University Apparatuses and Methods for Manipulating Droplets
US8349276B2 (en) 2002-09-24 2013-01-08 Duke University Apparatuses and methods for manipulating droplets on a printed circuit board
US8388909B2 (en) 2002-09-24 2013-03-05 Duke University Apparatuses and methods for manipulating droplets
US8048628B2 (en) 2002-09-24 2011-11-01 Duke University Methods for nucleic acid amplification on a printed circuit board
WO2004034028A2 (en) 2002-10-09 2004-04-22 The Board Of Trustees Of The University Of Illinois Microfluidic systems and components
US7030989B2 (en) 2002-10-28 2006-04-18 University Of Washington Wavelength tunable surface plasmon resonance sensor
US20060057581A1 (en) 2002-11-01 2006-03-16 Norchip As Microfabricated fluidic device for fragmentation
US20040189311A1 (en) 2002-12-26 2004-09-30 Glezer Eli N. Assay cartridges and methods of using the same
US7497997B2 (en) 2002-12-26 2009-03-03 Meso Scale Technologies, Llc Assay cartridges and methods of using the same
US20040137607A1 (en) 2003-01-09 2004-07-15 Yokogawa Electric Corporation Biochip cartridge
US20090022624A1 (en) 2003-01-14 2009-01-22 Micronics, Inc. Microfluidic devices for fluid manipulation and analysis
US8557198B2 (en) 2003-01-14 2013-10-15 Micronics, Inc. Microfluidic devices for fluid manipulation and analysis
US8318109B2 (en) 2003-01-14 2012-11-27 Micronics, Inc. Microfluidic devices for fluid manipulation and analysis
US7419638B2 (en) 2003-01-14 2008-09-02 Micronics, Inc. Microfluidic devices for fluid manipulation and analysis
US7416892B2 (en) 2003-01-21 2008-08-26 Micronics, Inc. Method and system for microfluidic manipulation, amplification and analysis of fluids, for example, bacteria assays and antiglobulin testing
US20050182301A1 (en) 2003-01-31 2005-08-18 Zimmer Technology, Inc. Lit retractor
US20040185551A1 (en) 2003-03-20 2004-09-23 Northeastern Ohio Universities College Of Medicine Self-contained assay device for rapid detection of biohazardous agents
US7820030B2 (en) 2003-04-16 2010-10-26 Handylab, Inc. System and method for electrochemical detection of biological compounds
US8105477B2 (en) 2003-04-16 2012-01-31 Handylab, Inc. System and method for electrochemical detection of biological compounds
US20100151475A1 (en) 2003-05-12 2010-06-17 Yokogawa Electric Corporation Chemical reaction cartridge, its fabrication method, and a chemical reaction cartridge drive system
US20040254559A1 (en) 2003-05-12 2004-12-16 Yokogawa Electric Corporation Chemical reaction cartridge, its fabrication method, and a chemical reaction cartridge drive system
US7854897B2 (en) 2003-05-12 2010-12-21 Yokogawa Electric Corporation Chemical reaction cartridge, its fabrication method, and a chemical reaction cartridge drive system
US7648835B2 (en) 2003-06-06 2010-01-19 Micronics, Inc. System and method for heating, cooling and heat cycling on microfluidic device
US7544506B2 (en) 2003-06-06 2009-06-09 Micronics, Inc. System and method for heating, cooling and heat cycling on microfluidic device
US7731906B2 (en) 2003-07-31 2010-06-08 Handylab, Inc. Processing particle-containing samples
US20050164373A1 (en) 2004-01-22 2005-07-28 Oldham Mark F. Diffusion-aided loading system for microfluidic devices
US20080227185A1 (en) 2004-01-28 2008-09-18 Norchip As Diagnostic System for Carrying Out a Nucleic Acid Sequence Amplification and Detection Process
US7491495B2 (en) 2004-02-20 2009-02-17 Roche Diagnostics Operations, Inc. Adsorption of nucleic acids to a solid phase
US20060257993A1 (en) 2004-02-27 2006-11-16 Mcdevitt John T Integration of fluids and reagents into self-contained cartridges containing sensor elements
US8105849B2 (en) 2004-02-27 2012-01-31 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements
US8101431B2 (en) 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US7935537B2 (en) 2004-03-11 2011-05-03 Handylab, Inc. Sample preparation device and method
US20050244308A1 (en) 2004-04-28 2005-11-03 Takeo Tanaami Chemical reaction cartridge, method of producing chemical reaction cartridge, and mechanism for driving chemical reaction cartridge
US20060166233A1 (en) 2004-05-03 2006-07-27 Handylab, Inc. Method and apparatus for processing polynucleotide-containing samples
US20060040379A1 (en) 2004-08-18 2006-02-23 Yokogawa Electric Corporation Biochip cartridge and biochip reader
US20070248958A1 (en) 2004-09-15 2007-10-25 Microchip Biotechnologies, Inc. Microfluidic devices
US7550267B2 (en) 2004-09-23 2009-06-23 University Of Washington Microscale diffusion immunoassay utilizing multivalent reactants
US20060079834A1 (en) 2004-10-13 2006-04-13 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US8133703B2 (en) 2004-10-27 2012-03-13 Ceoheid Closed-system multi-stage nucleic acid amplification reactions
US20080248590A1 (en) 2004-11-26 2008-10-09 Norchip As Device For Carrying Out A Biological Assay
US7405054B1 (en) 2004-12-13 2008-07-29 University Of Washington Uw Tech Transfer - Invention Licensing Signal amplification method for surface plasmon resonance-based chemical detection
US8017340B2 (en) 2004-12-23 2011-09-13 Abbott Point Of Care Inc. Nucleic acid separation and amplification
US6968978B1 (en) 2005-01-05 2005-11-29 William B Matthews Wall mountable dispenser for collapsible tubes
US20060246575A1 (en) 2005-01-13 2006-11-02 Micronics, Inc. Microfluidic rare cell detection device
US20060183216A1 (en) 2005-01-21 2006-08-17 Kalyan Handique Containers for liquid storage and delivery with application to microfluidic devices
US7644898B2 (en) 2005-03-28 2010-01-12 Compview Medical, Llc Medical boom with articulated arms and a base with preconfigured removable modular racks used for storing electronic and utility equipment
US20070042427A1 (en) 2005-05-03 2007-02-22 Micronics, Inc. Microfluidic laminar flow detection strip
US20060264782A1 (en) 2005-05-09 2006-11-23 Holmes Elizabeth A Point-of-care fluidic systems and uses thereof
US8394608B2 (en) 2005-05-09 2013-03-12 Biofire Diagnostics, Inc. Self-contained biological analysis
US20120132528A1 (en) 2005-05-11 2012-05-31 Advanced Liquid Logic, Inc. Methods of Dispensing and Withdrawing Liquid in an Electrowetting Device
US20080274513A1 (en) 2005-05-11 2008-11-06 Shenderov Alexander D Method and Device for Conducting Biochemical or Chemical Reactions at Multiple Temperatures
US8481125B2 (en) 2005-05-21 2013-07-09 Advanced Liquid Logic Inc. Mitigation of biomolecular adsorption with hydrophilic polymer additives
US20090298059A1 (en) 2005-05-25 2009-12-03 Walter Gumbrecht System for the Integrated and Automated Analysis of DNA or Protein and Method for Operating Said Type of System
US20060275813A1 (en) 2005-06-03 2006-12-07 Yokogawa Electric Corporation Cartridge for chemical reaction
US20110319279A1 (en) 2005-06-06 2011-12-29 Avantra Biosciences Corporation Assays Based on Liquid Flow Over Arrays
US20060275852A1 (en) 2005-06-06 2006-12-07 Montagu Jean I Assays based on liquid flow over arrays
US7919330B2 (en) 2005-06-16 2011-04-05 Advanced Liquid Logic, Inc. Method of improving sensor detection of target molcules in a sample within a fluidic system
US20100291588A1 (en) 2005-06-24 2010-11-18 The Board Of Regents Of The University Of Texas System Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
US20070017927A1 (en) 2005-07-07 2007-01-25 Roche Molecular Systems, Inc. Containers and methods for the automated handling of a liquid
US20070013733A1 (en) 2005-07-15 2007-01-18 Yokogawa Electric Corporation Cartridge for chemical reaction and information managing apparatus
US20070039974A1 (en) 2005-08-18 2007-02-22 Lloyd James J Dual-usage beverage dispensing system
US20100288789A1 (en) 2005-09-27 2010-11-18 Yokogawa Electric Corporation Chemical reaction cartridge and method of using same
US7789270B2 (en) 2005-09-27 2010-09-07 Yokogawa Electric Corporation Chemical reaction cartridge and method using same
US7858045B2 (en) 2005-09-30 2010-12-28 Yokogawa Electric Corporation Chemical reaction cartridge and method of using same
WO2007044917A2 (en) 2005-10-11 2007-04-19 Handylab, Inc. Polynucleotide sample preparation device
US20070184547A1 (en) 2005-10-11 2007-08-09 Kalyan Handique Polynucleotide sample preparation device
US8372340B2 (en) 2005-10-19 2013-02-12 Luminex Corporation Apparatus and methods for integrated sample preparation, reaction and detection
US8304253B2 (en) 2005-10-22 2012-11-06 Advanced Liquid Logic Inc Droplet extraction from a liquid column for on-chip microfluidics
US8551424B2 (en) 2005-11-17 2013-10-08 Siemens Aktiengesellschaft Apparatus for processing a sample comprising a biochip and reagents embedded in a biodegradable material, and processes thereof
US7763453B2 (en) 2005-11-30 2010-07-27 Micronics, Inc. Microfluidic mixing and analytic apparatus
US20120177543A1 (en) 2005-11-30 2012-07-12 Micronics, Inc. Microfluidic reactor system
US20120064597A1 (en) 2005-11-30 2012-03-15 Micronics, Inc. Microfluidic mixing and analytical apparatus
US7955836B2 (en) 2005-11-30 2011-06-07 Micronics, Inc. Microfluidic mixing and analytical apparatus
US20070178529A1 (en) 2006-01-13 2007-08-02 Micronics, Inc. Electromagnetically actuated valves for use in microfluidic structures
US20070219480A1 (en) 2006-02-09 2007-09-20 Dean Kamen Patch-sized fluid delivery systems and methods
US7364886B2 (en) 2006-02-28 2008-04-29 University Of Washington Chemical sensor enhanced by direct coupling of redox enzyme to conductive surface
US7659089B2 (en) 2006-02-28 2010-02-09 University Of Washington Chemical sensor enhanced by direct coupling of redox enzyme to conductive surface
US20090061450A1 (en) 2006-03-14 2009-03-05 Micronics, Inc. System and method for diagnosis of infectious diseases
US20120329142A1 (en) 2006-03-15 2012-12-27 Micronics, Inc. Integrated nucleic acid assays
US8222023B2 (en) 2006-03-15 2012-07-17 Micronics, Inc. Integrated nucleic acid assays
US20090148847A1 (en) 2006-03-15 2009-06-11 Micronics, Inc. Rapid magnetic flow assays
US20080182301A1 (en) 2006-03-24 2008-07-31 Kalyan Handique Microfluidic system for amplifying and detecting polynucleotides in parallel
US9040288B2 (en) 2006-03-24 2015-05-26 Handylab, Inc. Integrated system for processing microfluidic samples, and method of using the same
JP2012055321A (en) 2006-03-24 2012-03-22 Handylab Inc Integrated system for processing microfluidic sample, and method of using the same
WO2007112114A2 (en) 2006-03-24 2007-10-04 Handylab, Inc. Integrated system for processing microfluidic samples, and method of using same
US20120160826A1 (en) 2006-03-24 2012-06-28 Handylab, Inc. Heater unit for microfluidic diagnostic system
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US8323900B2 (en) 2006-03-24 2012-12-04 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US20070292941A1 (en) 2006-03-24 2007-12-20 Handylab, Inc. Integrated system for processing microfluidic samples, and method of using the same
US20110053289A1 (en) 2006-03-29 2011-03-03 Inverness Medical Switzerland Gmbh Assay Device and Method
US20070241068A1 (en) 2006-04-13 2007-10-18 Pamula Vamsee K Droplet-based washing
US8613889B2 (en) 2006-04-13 2013-12-24 Advanced Liquid Logic, Inc. Droplet-based washing
US20130252262A1 (en) 2006-04-13 2013-09-26 Advanced Liquid Logic Inc. Droplet-based affinity assays
US20120165238A1 (en) 2006-04-18 2012-06-28 Duke University Droplet-Based Surface Modification and Washing
US20110091989A1 (en) 2006-04-18 2011-04-21 Advanced Liquid Logic, Inc. Method of Reducing Liquid Volume Surrounding Beads
US7816121B2 (en) 2006-04-18 2010-10-19 Advanced Liquid Logic, Inc. Droplet actuation system and method
US8470606B2 (en) 2006-04-18 2013-06-25 Duke University Manipulation of beads in droplets and methods for splitting droplets
US20100116640A1 (en) 2006-04-18 2010-05-13 Advanced Liquid Logic, Inc. Droplet-Based Surface Modification and Washing
US8007739B2 (en) 2006-04-18 2011-08-30 Advanced Liquid Logic, Inc. Protein crystallization screening and optimization droplet actuators, systems and methods
US20120018306A1 (en) 2006-04-18 2012-01-26 Duke University Sample Processing Droplet Actuator, System and Method
US20100279374A1 (en) 2006-04-18 2010-11-04 Advanced Liquid Logic, Inc. Manipulation of Beads in Droplets and Methods for Manipulating Droplets
US8313895B2 (en) 2006-04-18 2012-11-20 Advanced Liquid Logic Inc Droplet-based surface modification and washing
US8313698B2 (en) 2006-04-18 2012-11-20 Advanced Liquid Logic Inc Droplet-based nucleic acid amplification apparatus and system
US20110203930A1 (en) 2006-04-18 2011-08-25 Advanced Liquid Logic, Inc. Bead Incubation and Washing on a Droplet Actuator
US20070275415A1 (en) 2006-04-18 2007-11-29 Vijay Srinivasan Droplet-based affinity assays
US7998436B2 (en) 2006-04-18 2011-08-16 Advanced Liquid Logic, Inc. Multiwell droplet actuator, system and method
US20100291578A1 (en) 2006-04-18 2010-11-18 Advanced Liquid Logic, Inc. Droplet-Based Pyrosequencing
US20110186433A1 (en) 2006-04-18 2011-08-04 Advanced Liquid Logic, Inc. Droplet-Based Particle Sorting
US20110180571A1 (en) 2006-04-18 2011-07-28 Advanced Liquid Logic, Inc. Droplet Actuators, Modified Fluids and Methods
US20080230386A1 (en) 2006-04-18 2008-09-25 Vijay Srinivasan Sample Processing Droplet Actuator, System and Method
US20090263834A1 (en) 2006-04-18 2009-10-22 Advanced Liquid Logic, Inc. Droplet Actuator Devices and Methods for Immunoassays and Washing
US8541176B2 (en) 2006-04-18 2013-09-24 Advanced Liquid Logic Inc. Droplet-based surface modification and washing
JP2009534653A (en) 2006-04-18 2009-09-24 アドバンスド・リキッド・ロジック・インコーポレイテッド Biochemistry based on droplets
US7851184B2 (en) 2006-04-18 2010-12-14 Advanced Liquid Logic, Inc. Droplet-based nucleic acid amplification method and apparatus
US7439014B2 (en) 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
WO2007120241A2 (en) 2006-04-18 2007-10-25 Advanced Liquid Logic, Inc. Droplet-based biochemistry
US7727723B2 (en) 2006-04-18 2010-06-01 Advanced Liquid Logic, Inc. Droplet-based pyrosequencing
US8637324B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US20130164742A1 (en) 2006-04-18 2013-06-27 Advanced Liquid Logic, Inc. Droplet-Based Pyrosequencing
US20110114490A1 (en) 2006-04-18 2011-05-19 Advanced Liquid Logic, Inc. Bead Manipulation Techniques
US8637317B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Method of washing beads
US20070242105A1 (en) 2006-04-18 2007-10-18 Vijay Srinivasan Filler fluids for droplet operations
US8389297B2 (en) 2006-04-18 2013-03-05 Duke University Droplet-based affinity assay device and system
US7901947B2 (en) 2006-04-18 2011-03-08 Advanced Liquid Logic, Inc. Droplet-based particle sorting
US7763471B2 (en) 2006-04-18 2010-07-27 Advanced Liquid Logic, Inc. Method of electrowetting droplet operations for protein crystallization
US20080038810A1 (en) 2006-04-18 2008-02-14 Pollack Michael G Droplet-based nucleic acid amplification device, system, and method
US8658111B2 (en) 2006-04-18 2014-02-25 Advanced Liquid Logic, Inc. Droplet actuators, modified fluids and methods
US8685754B2 (en) 2006-04-18 2014-04-01 Advanced Liquid Logic, Inc. Droplet actuator devices and methods for immunoassays and washing
US8137917B2 (en) 2006-04-18 2012-03-20 Advanced Liquid Logic, Inc. Droplet actuator devices, systems, and methods
US7815871B2 (en) 2006-04-18 2010-10-19 Advanced Liquid Logic, Inc. Droplet microactuator system
US8492168B2 (en) 2006-04-18 2013-07-23 Advanced Liquid Logic Inc. Droplet-based affinity assays
US20090155902A1 (en) 2006-04-18 2009-06-18 Advanced Liquid Logic, Inc. Manipulation of Cells on a Droplet Actuator
US8343636B2 (en) 2006-05-09 2013-01-01 University Of Washington Crosslinkable hole-transporting materials for organic light-emitting devices
US20110104747A1 (en) 2006-05-09 2011-05-05 Advanced Liquid Logic, Inc. Method of Concentrating Beads in a Droplet
US8041463B2 (en) 2006-05-09 2011-10-18 Advanced Liquid Logic, Inc. Modular droplet actuator drive
US7822510B2 (en) 2006-05-09 2010-10-26 Advanced Liquid Logic, Inc. Systems, methods, and products for graphically illustrating and controlling a droplet actuator
US7607460B2 (en) 2006-06-12 2009-10-27 Jpro Dairy International, Inc. Coupling assembly
US20120164627A1 (en) 2006-06-23 2012-06-28 Micronics, Inc. Methods and devices for microfluidic point-of-care immunoassays
US8110392B2 (en) 2006-06-23 2012-02-07 Micronics, Inc. Methods and devices for microfluidic point-of-care immunoassays
US20090197778A1 (en) 2006-06-27 2009-08-06 Zenteris Gmbh Heated Reaction Chamber For Processing A Biochip And Method For Controlling Said Reaction Chamber
US7655190B2 (en) 2006-08-03 2010-02-02 Yokogawa Electric Corporation Biochemical reaction apparatus and biochemical reaction method
US20080050287A1 (en) 2006-08-22 2008-02-28 Yokogawa Electric Corporation Chemical reaction apparatus
US20100150783A1 (en) 2006-08-22 2010-06-17 Yokogawa Electric Corporation Chemical reaction apparatus
US20080108122A1 (en) 2006-09-01 2008-05-08 State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon Microchemical nanofactories
US20080056948A1 (en) 2006-09-06 2008-03-06 Canon U.S. Life Sciences, Inc. Chip and cartridge design configuration for performing micro-fluidic assays
US20090325276A1 (en) 2006-09-27 2009-12-31 Micronics, Inc. Integrated microfluidic assay devices and methods
US8101403B2 (en) 2006-10-04 2012-01-24 University Of Washington Method and device for rapid parallel microfluidic molecular affinity assays
US20100304986A1 (en) 2006-12-14 2010-12-02 The Trustees Of The University Of Pennsylvania Mechanically actuated diagnostic device
US8338166B2 (en) 2007-01-04 2012-12-25 Lawrence Livermore National Security, Llc Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture
US20100093019A1 (en) 2007-01-12 2010-04-15 Environmental Biotechnology Crc Pty Limited Sample handling device
US7935316B2 (en) 2007-01-16 2011-05-03 Yokogawa Electric Corporation Chemical reaction cartridge and method for using
US7794669B2 (en) 2007-01-17 2010-09-14 Yokogawa Electric Corporation Chemical reaction cartridge
US20090304944A1 (en) 2007-01-22 2009-12-10 Advanced Liquid Logic, Inc. Surface Assisted Fluid Loading and Droplet Dispensing
US8685344B2 (en) 2007-01-22 2014-04-01 Advanced Liquid Logic, Inc. Surface assisted fluid loading and droplet dispensing
US20100068764A1 (en) 2007-02-09 2010-03-18 Advanced Liquid Logic, Inc. Droplet Actuator Devices and Methods Employing Magnetic Beads
US7863035B2 (en) 2007-02-15 2011-01-04 Osmetech Technology Inc. Fluidics devices
US20100194408A1 (en) 2007-02-15 2010-08-05 Advanced Liquid Logic, Inc. Capacitance Detection in a Droplet Actuator
US20100025250A1 (en) 2007-03-01 2010-02-04 Advanced Liquid Logic, Inc. Droplet Actuator Structures
US20130233712A1 (en) 2007-03-01 2013-09-12 Advanced Liquid Logic Inc. Method of Manipulating a Droplet
US8426213B2 (en) 2007-03-05 2013-04-23 Advanced Liquid Logic Inc Hydrogen peroxide droplet-based assays
US8506908B2 (en) 2007-03-09 2013-08-13 Vantix Holdings Limited Electrochemical detection system
US8208146B2 (en) 2007-03-13 2012-06-26 Advanced Liquid Logic, Inc. Droplet actuator devices, configurations, and methods for improving absorbance detection
US8440392B2 (en) 2007-03-22 2013-05-14 Advanced Liquid Logic Inc. Method of conducting a droplet based enzymatic assay
US8592217B2 (en) 2007-03-22 2013-11-26 Advanced Liquid Logic, Inc. Method of conducting an assay
US20130130936A1 (en) 2007-03-22 2013-05-23 Advanced Liquid Logic, Inc. Method of Conducting an Assay
US20130230875A1 (en) 2007-03-22 2013-09-05 Advanced Liquid Logic Inc. Enzymatic Assays for a Droplet Actuator
US20100048410A1 (en) 2007-03-22 2010-02-25 Advanced Liquid Logic, Inc. Bead Sorting on a Droplet Actuator
US8093062B2 (en) 2007-03-22 2012-01-10 Theodore Winger Enzymatic assays using umbelliferone substrates with cyclodextrins in droplets in oil
US8202686B2 (en) 2007-03-22 2012-06-19 Advanced Liquid Logic, Inc. Enzyme assays for a droplet actuator
US20130146461A1 (en) 2007-03-23 2013-06-13 Advanced Liquid Logic Inc Droplet Actuator Loading and Target Concentration
US8317990B2 (en) 2007-03-23 2012-11-27 Advanced Liquid Logic Inc. Droplet actuator loading and target concentration
US20100032293A1 (en) 2007-04-10 2010-02-11 Advanced Liquid Logic, Inc. Droplet Dispensing Device and Methods
US20100206094A1 (en) 2007-04-23 2010-08-19 Advanced Liquid Logic, Inc. Device and Method for Sample Collection and Concentration
US20100087012A1 (en) 2007-04-23 2010-04-08 Advanced Liquid Logic, Inc. Sample Collector and Processor
US20100130369A1 (en) 2007-04-23 2010-05-27 Advanced Liquid Logic, Inc. Bead-Based Multiplexed Analytical Methods and Instrumentation
US20100136554A1 (en) 2007-04-25 2010-06-03 3M Innovative Properties Company Supported reagents, methods, and devices
US7939021B2 (en) 2007-05-09 2011-05-10 Advanced Liquid Logic, Inc. Droplet actuator analyzer with cartridge
US7669597B2 (en) 2007-05-16 2010-03-02 Mystic Pharmaceuticals, Inc. Combination unit dose dispensing containers
US20080283439A1 (en) 2007-05-16 2008-11-20 Mystic Pharmaceuticals, Inc. Combination unit dose dispensing containers
US20100307922A1 (en) 2007-05-24 2010-12-09 Digital Biosystems Electrowetting based digital microfluidics
US8404440B2 (en) 2007-06-07 2013-03-26 Norchip A/S Device for carrying out cell lysis and nucleic acid extraction
US20100297754A1 (en) 2007-06-07 2010-11-25 Norchip A/S Device for carrying out cell lysis and nucleic acid extraction
US20100323405A1 (en) 2007-06-22 2010-12-23 Advanced Liquid Logic, Inc. Droplet-Based Nucleic Acid Amplification in a Temperature Gradient
US20080314167A1 (en) 2007-06-25 2008-12-25 Valentin Kahl Sample Chamber
US20110048951A1 (en) 2007-06-27 2011-03-03 Digital Biosystems Digital microfluidics based apparatus for heat-exchanging chemical processes
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US20120171759A1 (en) 2007-07-13 2012-07-05 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US20090221059A1 (en) 2007-07-13 2009-09-03 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US20120122108A1 (en) 2007-07-13 2012-05-17 Handylab, Inc. Microfluidic cartridge
US20100233824A1 (en) 2007-07-20 2010-09-16 Koninklijke Philips Electronics N.V. Microfluidic methods and systems for use in detecting analytes
US20120271127A1 (en) 2007-07-31 2012-10-25 Micronics, Inc. Sanitary swab collection system, microfluidic assay device, and methods for diagnostic assays
US8216832B2 (en) 2007-07-31 2012-07-10 Micronics, Inc. Sanitary swab collection system, microfluidic assay device, and methods for diagnostic assays
US20100120130A1 (en) 2007-08-08 2010-05-13 Advanced Liquid Logic, Inc. Droplet Actuator with Droplet Retention Structures
US20110303542A1 (en) 2007-08-08 2011-12-15 Advanced Liquid Logic, Inc. Use of Additives for Enhancing Droplet Operations
US20130233425A1 (en) 2007-08-08 2013-09-12 Advanced Liquid Logic Inc. Enhancing and/or Maintaining Oil Film Stability in a Droplet Actuator
US8268246B2 (en) 2007-08-09 2012-09-18 Advanced Liquid Logic Inc PCB droplet actuator fabrication
US20110143339A1 (en) 2007-08-17 2011-06-16 Craig Wisniewski Device, System and Method for Processing a Sample
US20110086377A1 (en) 2007-08-24 2011-04-14 Advanced Liquid Logic, Inc. Bead Manipulations on a Droplet Actuator
US8591830B2 (en) 2007-08-24 2013-11-26 Advanced Liquid Logic, Inc. Bead manipulations on a droplet actuator
US20100282608A1 (en) 2007-09-04 2010-11-11 Advanced Liquid Logic, Inc. Droplet Actuator with Improved Top Substrate
US7736891B2 (en) 2007-09-11 2010-06-15 University Of Washington Microfluidic assay system with dispersion monitoring
US20090180931A1 (en) 2007-09-17 2009-07-16 Sequenom, Inc. Integrated robotic sample transfer device
US20100236928A1 (en) 2007-10-17 2010-09-23 Advanced Liquid Logic, Inc. Multiplexed Detection Schemes for a Droplet Actuator
US20100282609A1 (en) 2007-10-17 2010-11-11 Advanced Liquid Logic, Inc. Reagent Storage and Reconstitution for a Droplet Actuator
US8460528B2 (en) 2007-10-17 2013-06-11 Advanced Liquid Logic Inc. Reagent storage and reconstitution for a droplet actuator
US8454905B2 (en) 2007-10-17 2013-06-04 Advanced Liquid Logic Inc. Droplet actuator structures
US20100236929A1 (en) 2007-10-18 2010-09-23 Advanced Liquid Logic, Inc. Droplet Actuators, Systems and Methods
US7820391B2 (en) 2007-11-06 2010-10-26 Osmetech Molecular Diagnostics Baseless nucleotide analogues and uses thereof
US20100308051A1 (en) 2007-12-06 2010-12-09 Lutz Weber Microfluid storage device
US9211538B2 (en) 2007-12-06 2015-12-15 Thinxxs Microtechnology Ag Microfluid storage device
US8562807B2 (en) 2007-12-10 2013-10-22 Advanced Liquid Logic Inc. Droplet actuator configurations and methods
US20100307917A1 (en) 2007-12-10 2010-12-09 Advanced Liquid Logic, Inc. Droplet Actuator Configurations and Methods
US20100270156A1 (en) 2007-12-23 2010-10-28 Advanced Liquid Logic, Inc. Droplet Actuator Configurations and Methods of Conducting Droplet Operations
US20090171311A1 (en) 2007-12-28 2009-07-02 Aktivpak, Inc. Dispenser and therapeutic package suitable for administering a therapeutic substance to a subject, along with method relating to same
US20150024480A1 (en) 2008-01-09 2015-01-22 Keck Graduate Institute System, apparatus and method for material preparation and/or handling
US20100178697A1 (en) 2008-01-09 2010-07-15 Keck Graduate Institute System, apparatus and method for material preparation and/or handling
US20090182575A1 (en) 2008-01-11 2009-07-16 General Electric Company System and method to manage a workflow in delivering healthcare
US8367370B2 (en) 2008-02-11 2013-02-05 Wheeler Aaron R Droplet-based cell culture and cell assays using digital microfluidics
US20100311599A1 (en) 2008-02-11 2010-12-09 Wheeler Aaron R Cell culture and cell assays using digital microfluidics
US20110207621A1 (en) 2008-02-21 2011-08-25 Avantra Biosciences Corporation Assays Based on Liquid Flow over Arrays
USD599832S1 (en) 2008-02-25 2009-09-08 Advanced Liquid Logic, Inc. Benchtop instrument housing
US20090221091A1 (en) 2008-03-03 2009-09-03 Yokogawa Electric Corporation Chemical reaction cartridge, mixture generating method and control device of chemical reaction cartridge
US20100226199A1 (en) 2008-03-03 2010-09-09 Yokogawa Electric Corporation Chemical reaction cartridge, mixture generating method and control device of chemical reaction cartridge
US20090223989A1 (en) 2008-03-04 2009-09-10 R.J. Reynolds Tobacco Company Dispensing Container
US20110104725A1 (en) 2008-05-02 2011-05-05 Advanced Liquid Logic, Inc. Method of Effecting Coagulation in a Droplet
US20110104816A1 (en) 2008-05-03 2011-05-05 Advanced Liquid Logic, Inc. Method of Loading a Droplet Actuator
US8088578B2 (en) 2008-05-13 2012-01-03 Advanced Liquid Logic, Inc. Method of detecting an analyte
US20110097763A1 (en) 2008-05-13 2011-04-28 Advanced Liquid Logic, Inc. Thermal Cycling Method
JP2011520449A (en) 2008-05-13 2011-07-21 アドヴァンスト リキッド ロジック インコーポレイテッド Droplet actuator device, system, and method
US8580209B2 (en) 2008-06-02 2013-11-12 Boehringer Ingelheim Microparts Gmbh Microfluidic foil structure for metering of fluids
US20110186466A1 (en) 2008-06-19 2011-08-04 Boehringer Ingelheim Microparts Gmbh Fluid metering container
US8795607B2 (en) 2008-06-19 2014-08-05 Boehringer Ingelheim Microparts Gmbh Fluid metering container
US20100021910A1 (en) 2008-07-18 2010-01-28 Canon U.S. Life Sciences, Inc. Methods and Systems for Microfluidic DNA Sample Preparation
US20120261264A1 (en) 2008-07-18 2012-10-18 Advanced Liquid Logic, Inc. Droplet Operations Device
USD600503S1 (en) 2008-07-29 2009-09-22 Ragsdale Donald W Food tray with waste collection feature
US20100035349A1 (en) 2008-08-06 2010-02-11 The Trustees Of The University Of Pennsylvania Biodetection Cassette with Automated Actuator
US20130178968A1 (en) 2008-08-13 2013-07-11 Advanced Liquid Logic, Inc. Methods, Systems, and Products for Conducting Droplet Operations
US8364315B2 (en) 2008-08-13 2013-01-29 Advanced Liquid Logic Inc. Methods, systems, and products for conducting droplet operations
WO2010025302A2 (en) 2008-08-27 2010-03-04 Life Technologies Corporation Apparatus for and method of processing biological samples
US8356763B2 (en) 2008-09-08 2013-01-22 California Institute Of Technology Mechanical lysis arrangements and methods
US8201765B2 (en) 2008-09-08 2012-06-19 California Institute Of Technology Mechanical lysis arrangements and methods
US8216529B2 (en) 2008-09-15 2012-07-10 Abbott Point Of Care Inc. Fluid-containing pouches with reduced gas exchange and methods for making same
US20100173394A1 (en) 2008-09-23 2010-07-08 Colston Jr Billy Wayne Droplet-based assay system
US20110240471A1 (en) 2008-10-01 2011-10-06 Tecan Trading Ag Exchangeable carriers pre-loaded with reagent depots for digital microfluidics
US8187864B2 (en) 2008-10-01 2012-05-29 The Governing Council Of The University Of Toronto Exchangeable sheets pre-loaded with reagent depots for digital microfluidics
US8318439B2 (en) 2008-10-03 2012-11-27 Micronics, Inc. Microfluidic apparatus and methods for performing blood typing and crossmatching
US20130142708A1 (en) 2008-10-03 2013-06-06 Micronics, Inc. Microfluidic apparatus and methods for performing blood typing and crossmatching
US8053239B2 (en) 2008-10-08 2011-11-08 The Governing Council Of The University Of Toronto Digital microfluidic method for protein extraction by precipitation from heterogeneous mixtures
US20120083046A1 (en) 2008-10-10 2012-04-05 The Governing Council Of The University Of Toronto Hybrid digital and channel microfluidic devices and methods of use thereof
US8342367B2 (en) 2008-10-16 2013-01-01 Automatic Bar Controls, Inc. Cassette and vat supply source for an on-demand mixing and distributing of a food product
US8518662B2 (en) 2008-11-13 2013-08-27 Boule Medical Ab Disposable cassette and method of use for blood analysis on blood analyzer
US8247191B2 (en) 2008-11-13 2012-08-21 Ritzen Kalle Disposable cassette and method of use for blood analysis on blood analyzer
US20110311980A1 (en) 2008-12-15 2011-12-22 Advanced Liquid Logic, Inc. Nucleic Acid Amplification and Sequencing on a Droplet Actuator
US8701906B1 (en) 2008-12-31 2014-04-22 Blast Max Llc Ingredient dispensing cap for mixing beverages with push-pull drinking spout
US20100190263A1 (en) 2009-01-23 2010-07-29 Advanced Liquid Logic, Inc. Bubble Techniques for a Droplet Actuator
US20130011912A1 (en) 2009-01-30 2013-01-10 Micronics, Inc. Portable high gain fluorescence detection system
US8431389B2 (en) 2009-01-30 2013-04-30 Micronics, Inc. Portable high gain fluorescence detection system
US8329453B2 (en) 2009-01-30 2012-12-11 Micronics, Inc. Portable high gain fluorescence detection system
US20120107811A1 (en) 2009-02-06 2012-05-03 Kelso David M Burstable liquid packaging and uses thereof
US8202736B2 (en) 2009-02-26 2012-06-19 The Governing Council Of The University Of Toronto Method of hormone extraction using digital microfluidics
US20120085645A1 (en) 2009-02-26 2012-04-12 The Governing Council Of The University Of Toronto Digital microfluidic liquid-liquid extraction device and method of use thereof
US20100224511A1 (en) 2009-03-06 2010-09-09 Barry Boatner Bifurcated beverage can with unified opening and mixing operation
US20120156112A1 (en) 2009-04-13 2012-06-21 Micronics, Inc. Microfluidic clinical analyzer
US20100317093A1 (en) 2009-06-10 2010-12-16 Cynvenio Biosystems, Inc. Flexible pouch and cartridge with fluidic circuits
US20120142070A1 (en) 2009-06-12 2012-06-07 Micronics, Inc. Rehydratable matrices for dry storage of taq polymerase in a microfluidic device
US20120156750A1 (en) 2009-06-12 2012-06-21 Micronics, Inc. Compositions and methods for dehydrated storage of on-board reagents in microfluidic devices
US8426214B2 (en) 2009-06-12 2013-04-23 University Of Washington System and method for magnetically concentrating and detecting biomarkers
US20100331522A1 (en) 2009-06-26 2010-12-30 Bruce Irvine Capture and elution of bio-analytes via beads that are used to disrupt specimens
US9260475B2 (en) 2009-06-26 2016-02-16 Claremont Biosolutions Llc Capture and elution of bio-analytes via beads that are used to disrupt specimens
US20120187117A1 (en) 2009-07-11 2012-07-26 Thinxxs Microtechnology Ag Fluid reservoir
US20120196280A1 (en) 2009-07-17 2012-08-02 Norchip A/S Microfabricated device for metering an analyte
US20120044299A1 (en) 2009-08-14 2012-02-23 Advanced Liquid Logic, Inc. Droplet Actuator Devices and Methods
US20110159578A1 (en) 2009-09-15 2011-06-30 James Hal Godsey Multiple-input Analytical System
US20110076692A1 (en) 2009-09-29 2011-03-31 Ramakrishna Sista Detection of Cardiac Markers on a Droplet Actuator
US20110129931A1 (en) 2009-10-20 2011-06-02 Agency For Science, Technology And Research Microfluidic system for detecting a biological entity in a sample
US20130059366A1 (en) 2009-11-06 2013-03-07 Duke University Integrated Droplet Actuator for Gel; Electrophoresis and Molecular Analysis
US8394641B2 (en) 2009-12-21 2013-03-12 Advanced Liquid Logic Inc. Method of hydrolyzing an enzymatic substrate
US20130130262A1 (en) 2010-01-29 2013-05-23 C. Frederick Battrell Sample-to-answer microfluidic cartridge
US20110207209A1 (en) 2010-02-17 2011-08-25 Aaron Hammons Culture systems, apparatus, and related methods and articles
US20130225452A1 (en) 2010-02-25 2013-08-29 Advanced Liquid Logic Inc Method of Preparing a Nucleic Acid Library
WO2011106314A2 (en) 2010-02-25 2011-09-01 Advanced Liquid Logic, Inc. Method of making nucleic acid libraries
US20130225450A1 (en) 2010-02-25 2013-08-29 Advanced Liquid Logic Inc Method of Ligating a Nucleic Acid
US20130203606A1 (en) 2010-02-25 2013-08-08 Advanced Liquid Logic Inc Method of Preparing a Nucleic Acid Library
US20130217103A1 (en) 2010-03-30 2013-08-22 Advanced Liquid Logic Inc Droplet Operations Platform
WO2011127040A2 (en) 2010-04-09 2011-10-13 Molecular Devices, Inc. High throughput screening of ion channels
US20110318824A1 (en) 2010-05-31 2011-12-29 Yokogawa Electric Corporation Cartridge system for chemical processing
JP2011252768A (en) 2010-06-01 2011-12-15 Sharp Corp Micro analysis chip, analyzer using the same and liquid feeding method
US20130217113A1 (en) 2010-07-15 2013-08-22 Advanced Liquid Logic Inc. System for and methods of promoting cell lysis in droplet actuators
US20120071342A1 (en) 2010-09-15 2012-03-22 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
US20130341231A1 (en) 2010-11-10 2013-12-26 Boehringer Ingelheim Microparts Gmbh Blister packaging for liquid
US20130327672A1 (en) 2010-11-10 2013-12-12 Boehringer Ingelheim Microparts Gmbh Blister packaging for liquid and use thereof and method for supplying a liquid to a fluidic assembly
US20140000223A1 (en) 2010-11-10 2014-01-02 Boehringer Ingelheim Microparts Gmbh Method for filling a blister packaging with liquid, and blister packaging with a cavity for filling with liquid
US20140160877A1 (en) 2010-12-20 2014-06-12 Boehringer Ingelheim Microparts Gmbh Method for mixing at least one sample solution having at least one reagent, and device
US20120252008A1 (en) 2010-12-23 2012-10-04 Claremont Biosolutions, Llc Compositions and methods for capture and elution of biological materials via particulates
US8663974B2 (en) 2010-12-23 2014-03-04 Claremont Biosolutions Llc Compositions and methods for capture and elution of biological materials via particulates
US20140127773A1 (en) 2010-12-23 2014-05-08 Claremont Biosolutions, Llc Compositions and methods for capture and elution of biological materials via particulates
US8951781B2 (en) 2011-01-10 2015-02-10 Illumina, Inc. Systems, methods, and apparatuses to image a sample for biological or chemical analysis
US20120270305A1 (en) 2011-01-10 2012-10-25 Illumina Inc. Systems, methods, and apparatuses to image a sample for biological or chemical analysis
US20140045275A1 (en) 2011-02-15 2014-02-13 Robert Bosch Gmbh Apparatus for hermetically sealed storage of liquids for a microfluidic system
WO2012151192A2 (en) 2011-05-02 2012-11-08 Advanced Liquid Logic, Inc. Molecular diagnostics platform
US20130178374A1 (en) 2011-07-06 2013-07-11 Advanced Liquid Logic, Inc. Systems for and Methods of Hybrid Pyrosequencing
US20130017544A1 (en) 2011-07-11 2013-01-17 Advanced Liquid Logic Inc High Resolution Melting Analysis on a Droplet Actuator
US20130018611A1 (en) 2011-07-11 2013-01-17 Advanced Liquid Logic Inc Systems and Methods of Measuring Gap Height
US20130020202A1 (en) 2011-07-22 2013-01-24 Feiglin Marc N Cartridge and System for Manipulating Samples in Liquid Droplets
US20150024436A1 (en) 2011-10-21 2015-01-22 Integenx Inc, Sample preparation, processing and analysis systems
WO2013059750A1 (en) 2011-10-21 2013-04-25 Integenx Inc. Sample preparation, processing and analysis systems
USD702364S1 (en) 2011-12-20 2014-04-08 SYFR, Inc. Auto-staining cartridge
US20130302787A1 (en) 2012-05-08 2013-11-14 Northwestern University Cartridge for use in an automated system for isolating an analyte from a sample, and methods of use
US20150132860A1 (en) 2012-05-15 2015-05-14 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
US20130331298A1 (en) 2012-06-06 2013-12-12 Great Basin Scientific Analyzer and disposable cartridge for molecular in vitro diagnostics
US20140000735A1 (en) 2012-06-28 2014-01-02 Thinxxs Microtechnology Ag Micro reservoir, particularly for integration in a microfluidic flow cell
US20150298118A1 (en) 2012-09-28 2015-10-22 Agplus Diagnostics Ltd Test Device and Sample Carrier
WO2014049371A2 (en) 2012-09-28 2014-04-03 Agplus Diagnostics Ltd Test device and sample carrier
US10495656B2 (en) 2012-10-24 2019-12-03 Genmark Diagnostics, Inc. Integrated multiplex target analysis
WO2014066704A1 (en) 2012-10-24 2014-05-01 Genmark Diagnostics, Inc. Integrated multiplex target analysis
US20180223345A1 (en) 2012-10-24 2018-08-09 Genmark Diagnostics, Inc. Integrated multiplex target analysis
US20140322706A1 (en) 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
US20150323555A1 (en) 2012-10-24 2015-11-12 Genmark Diagnostics, Inc. Integrated multiplex target analysis
US20140194305A1 (en) 2012-10-24 2014-07-10 Jon Faiz Kayyem Integrated multiplex target analysis
US9957553B2 (en) 2012-10-24 2018-05-01 Genmark Diagnostics, Inc. Integrated multiplex target analysis
US20140170641A1 (en) 2012-12-19 2014-06-19 Nanomr, Inc. Sample entry
US20150346097A1 (en) 2012-12-21 2015-12-03 Micronics, Inc. Portable fluorescence detection system and microassay cartridge
US20160146803A1 (en) 2013-01-25 2016-05-26 Carclo Technical Plastics Limited Heterogenous assay
US20140220702A1 (en) 2013-01-31 2014-08-07 Luminex Corporation Fluid retention plates and analysis cartridges
US20140255275A1 (en) 2013-03-07 2014-09-11 Quidel Corporation Dual chamber liquid packaging system
US20140252079A1 (en) 2013-03-11 2014-09-11 Promega Corporation Analyzer with machine readable protocol prompting
US20140261708A1 (en) 2013-03-15 2014-09-18 Genmark Diagnostics, Inc. Devices and methods for manipulating deformable fluid vessels
US9222623B2 (en) 2013-03-15 2015-12-29 Genmark Diagnostics, Inc. Devices and methods for manipulating deformable fluid vessels
US10391489B2 (en) 2013-03-15 2019-08-27 Genmark Diagnostics, Inc. Apparatus and methods for manipulating deformable fluid vessels
US20140263439A1 (en) 2013-03-15 2014-09-18 Genmark Diagnostics, Inc. Apparatus and methods for manipulating deformable fluid vessels
US20160339426A1 (en) 2013-03-15 2016-11-24 Genmark Diagnostics, Inc. Apparatus, devices, and methods for manipulating deformable fluid vessels
US9410663B2 (en) 2013-03-15 2016-08-09 Genmark Diagnostics, Inc. Apparatus and methods for manipulating deformable fluid vessels
US9453613B2 (en) 2013-03-15 2016-09-27 Genmark Diagnostics, Inc. Apparatus, devices, and methods for manipulating deformable fluid vessels
US20140370609A1 (en) 2013-04-05 2014-12-18 Roche Molecular Systems, Inc. Analysis system for a biological sample
USD881409S1 (en) 2013-10-24 2020-04-14 Genmark Diagnostics, Inc. Biochip cartridge
USD815754S1 (en) 2014-05-16 2018-04-17 Cytonome/St, Llc Droplet sorter
WO2015191916A1 (en) 2014-06-11 2015-12-17 Micronics, Inc. Microfluidic cartridges and apparatus with integrated assay controls for analysis of nucleic acids
US9498778B2 (en) 2014-11-11 2016-11-22 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
US20160129445A1 (en) 2014-11-11 2016-05-12 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
US9598722B2 (en) 2014-11-11 2017-03-21 Genmark Diagnostics, Inc. Cartridge for performing assays in a closed sample preparation and reaction system
US20160129437A1 (en) 2014-11-11 2016-05-12 Advanced Liquid Logic, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation
US20160130640A1 (en) 2014-11-11 2016-05-12 Genmark Diagnostics, Inc. Cartridge for performing assays in a closed sample preparation and reaction system
US20160131672A1 (en) 2014-11-11 2016-05-12 Genmark Diagnostics, Inc. Redundant identification for sample tracking on a diagnostic device
USD815752S1 (en) 2014-11-28 2018-04-17 Randox Laboratories Ltd. Biochip well
USD804808S1 (en) 2015-09-01 2017-12-12 Comprehensive Telemedicine Storage and carry case for telemedicine devices
US20170181314A1 (en) 2015-12-17 2017-06-22 Hewlett Packard Enterprise Development Lp Bay for removable device
USD800337S1 (en) 2016-01-27 2017-10-17 Phd Preventative Health Care And Diagnostics, Inc. Medical tray assembly
US20180015454A1 (en) 2016-07-12 2018-01-18 Wi, Inc. Disposable diagnostic device with vented priming fluid passage for volumetric control of sample and reagents and method of performing a diagnosis therewith
US20180095100A1 (en) 2016-09-19 2018-04-05 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
USD819225S1 (en) * 2017-01-19 2018-05-29 Life Technologies Corporation Capillary electrophoresis instrument
USD831224S1 (en) 2017-03-23 2018-10-16 Bonraybio Co., Ltd. Test strip
USD830573S1 (en) 2017-05-30 2018-10-09 Qualigen, Inc. Reagent pack
USD845503S1 (en) * 2017-11-17 2019-04-09 Genmark Diagnostics, Inc. Instrument

Non-Patent Citations (17)

* Cited by examiner, † Cited by third party
Title
Beaucage et al., "Tetrahedron Report No. 329: The Functionalization of Oligonucleotides via Phosphoramidite Derivatives," Tetrahedron vol. 49, No. 10, pp. 1925-2963 (1993).
Erickson et al., "Integrated Microfluidic Devices," Elsevier B.V., 16 pages (2003).
Findlay et al., "Automated Closed-Vessel System for in Vitro Diagnostics Based on Polymerase Chain Reaction," Clinical Chemistry, 39:9, pp. 1927-1933, 1993).
Focke et al., "Lab-on-a-Foil: Microfluidics on Thin and Flexible Films," The Royal Society of Chemistry, pp. 1365-1386 (2010).
Letsinger et al., "Hybridization of Alternating Cationic/ Anionic Oligonucleotides to RNA Segments," Nucleosides & Nucleotides vol. 13, No. 6&7, pp. 1597-1605 (1994).
Malic et al., "Current State of Intellectual Property in Microfluidic Nucleic Acid Analysis," McGill University, Bentham Science Publishers, 18 pages (2007).
Mesmaeker et al., "Comparison of Rigid and Flexible Backbones in Antisense Oligonucleotides," Bioorganic & Medicinal Chem. Letters, vol. 4, No. 3, pp. 395-398 (1994).
Non-Final Office Action in U.S. Appl. No. 29/623,925, 9 pages, (dated Sep. 6, 2018).
Non-final Office Action of U.S. Appl. No. 29/623,931 dated Feb. 21, 2019, 14 pages.
Office Action in U.S. Appl. No. 16/541,893, dated Feb. 28, 2020, 14 pages.
Respiratory Pathogen (RP) Panel. Online, published date unknown. Retrieved on Dec. 23, 2018 from URL: https://www.genmarkdx.com/solutions/panels/eplex-panels/respiratory-pathogen-panel/.
Sample to Answer Genetic System-Key Tech. Available in 2017. *
Sample to Answer Genetic System—Key Tech. Available in 2017. *
U.S. Appl. No. 11/883,896, filed Oct. 2009, Graeme Huntley.
U.S. Appl. No. 11/993,705, filed Aug. 2010, John McDevitt et al.
U.S. Appl. No. 62/396,449, filed Sep. 2016, Nguyen.
Vandeventer et al., "Mechanical Disruption of Lysis-Resistant Bacterial Cells by Use of a Miniature, Low-Power, Disposable Device," American Society for Microbiology, Journal of Clinical Microbiology, 49:7, pp. 2533-2539 (Jul. 2011).

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD981570S1 (en) * 2021-10-25 2023-03-21 Dongguan Hongyu Plastic Co., Ltd. Spa apparatus

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