USD1036656S1 - Applicator - Google Patents

Applicator Download PDF

Info

Publication number
USD1036656S1
USD1036656S1 US29/750,763 US202029750763F USD1036656S US D1036656 S1 USD1036656 S1 US D1036656S1 US 202029750763 F US202029750763 F US 202029750763F US D1036656 S USD1036656 S US D1036656S
Authority
US
United States
Prior art keywords
applicator
view
design
dot
ornamental design
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
US29/750,763
Inventor
Matthew Gene Davidson
Jayson Michael Rieger
Eugene Scavola
Paul Daly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Verrica Pharmaceuticals Inc
Original Assignee
Verrica Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Verrica Pharmaceuticals Inc filed Critical Verrica Pharmaceuticals Inc
Priority to US29/750,763 priority Critical patent/USD1036656S1/en
Assigned to VERRICA PHARMACEUTICALS, INC. reassignment VERRICA PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: DAVIDSON, MATTHEW GENE, DALY, PAUL, Rieger, Jayson Michael, SCAVOLA, Eugene
Assigned to ORBIMED ROYALTY & CREDIT OPPORTUNITIES IV, LP reassignment ORBIMED ROYALTY & CREDIT OPPORTUNITIES IV, LP SECURITY INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: VERRICA PHARMACEUTICALS INC.
Application granted granted Critical
Publication of USD1036656S1 publication Critical patent/USD1036656S1/en
Assigned to ORBIMED ROYALTY & CREDIT OPPORTUNITIES IV, LP reassignment ORBIMED ROYALTY & CREDIT OPPORTUNITIES IV, LP SECURITY INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: VERRICA PHARMACEUTICALS INC.
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Description

FIG. 1 is a perspective view of an applicator;
FIG. 2 is a right side view thereof, the left side view being a mirror image to the right side view;
FIG. 3 is a top view thereof; and,
FIG. 4 is a bottom view thereof.
The surface shading shown in FIGS. 1-2 indicates that the claimed applicator is transparent. Material, texture, color, surface finish and surface ornamentation form no part of the claimed design.
The dot-dash-dot lines represent the bounds of the claimed design that form no part of the claimed design. The remaining broken lines illustrate portions of the applicator that form no part of the claimed design.

Claims (1)

    CLAIM
  1. The ornamental design for an applicator, as shown and described.
US29/750,763 2017-06-15 2020-09-16 Applicator Active USD1036656S1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US29/750,763 USD1036656S1 (en) 2017-06-15 2020-09-16 Applicator

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29/607,744 USD900312S1 (en) 2017-06-15 2017-06-15 Applicator
US29/750,763 USD1036656S1 (en) 2017-06-15 2020-09-16 Applicator

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US29/607,744 Division USD900312S1 (en) 2017-06-15 2017-06-15 Applicator

Publications (1)

Publication Number Publication Date
USD1036656S1 true USD1036656S1 (en) 2024-07-23

Family

ID=72912995

Family Applications (2)

Application Number Title Priority Date Filing Date
US29/607,744 Active USD900312S1 (en) 2017-06-15 2017-06-15 Applicator
US29/750,763 Active USD1036656S1 (en) 2017-06-15 2020-09-16 Applicator

Family Applications Before (1)

Application Number Title Priority Date Filing Date
US29/607,744 Active USD900312S1 (en) 2017-06-15 2017-06-15 Applicator

Country Status (1)

Country Link
US (2) USD900312S1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12221452B2 (en) 2017-10-04 2025-02-11 Verrica Pharmaceuticals Inc. Synthesis of cantharidin
US12233042B2 (en) 2017-06-06 2025-02-25 Verrica Pharmaceuticals Inc. Treatment of cutaneous disorders
US12290651B2 (en) 2017-06-15 2025-05-06 Verrica Pharmaceuticals Inc. Devices and methods for the treatment of body surface disorders

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL315573A (en) 2013-08-21 2024-11-01 Verrica Pharmaceuticals Inc Preparations, methods and systems for the treatment of skin disorders
USD900312S1 (en) * 2017-06-15 2020-10-27 Verrica Pharmaceuticals, Inc. Applicator
USD928317S1 (en) * 2019-10-04 2021-08-17 Shukla Medical Jaw for a surgical instrument
USD998793S1 (en) * 2019-10-04 2023-09-12 Shukla Medical Jaw for a surgical instrument
USD983407S1 (en) * 2020-10-20 2023-04-11 Verrica Pharmaceuticals Inc. Ampule crush tool
USD928308S1 (en) * 2020-12-03 2021-08-17 Sal C. Mangeri Applicator tip

Citations (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1744893A (en) 1926-10-02 1930-01-28 George N Hein Hypodermic syringe
CH204207A (en) 1938-03-10 1939-04-30 Richard Graebener Fa Bottle cap.
GB587994A (en) 1945-01-01 1947-05-12 Harry Milman Bickle Improvements relating to stoppers for bottles and other containers
US3393962A (en) 1964-12-04 1968-07-23 Quill Res & Dev Corp Liquid applicator
US3981924A (en) 1974-04-22 1976-09-21 International Flavors & Fragrances Inc. Diels-Alder adduct product
JPS51141863A (en) 1975-06-02 1976-12-07 Nippon Nohyaku Co Ltd Process for preparing organo-phosphoric acid esters
US4148874A (en) 1977-06-13 1979-04-10 The Procter & Gamble Company Dermatological compositions
US4157967A (en) 1976-03-25 1979-06-12 Baxter Travenol Laboratories, Inc. Blood filter
US4299006A (en) 1980-02-19 1981-11-10 Cruz Miguel M Elastic drip guard for paint brushes
US4413154A (en) 1982-09-27 1983-11-01 Mobil Oil Corporation Diels-Alder cyclodimerization over a carbon molecular sieve catalyst
JPH0558914A (en) 1991-08-27 1993-03-09 Shiseido Co Ltd Skin external preparation
JPH05255367A (en) 1992-02-28 1993-10-05 Jitsuei O Production of cantharidin derivative composition and anti-viral agents containing it
US5445462A (en) 1993-08-03 1995-08-29 Medi-Flex Hospital Products, Inc. Liquid applicator
US5464855A (en) 1994-08-09 1995-11-07 Warner-Lambert Company Thiophene-2-carboxamidotetrazoles and pharmaceutical use thereof
US5590780A (en) 1995-06-22 1997-01-07 Wheaton Holding, Inc. Unit dose assembly
US5702694A (en) 1993-08-17 1997-12-30 Schering-Plough Healthcare Products, Inc. Compositions for treating corns, calluses and warts
JPH10114626A (en) 1996-10-07 1998-05-06 L'oreal Sa Use of organopolysilanes with elastomeric properties for use in combination with organic phases in products for nail make-up removal
JPH11319064A (en) 1998-05-18 1999-11-24 West Agro Inc Improved filming composition for animal skin prophylactic and protective agent
JPH11335303A (en) 1998-05-26 1999-12-07 Lion Corp Method for enhancing bitterness and external preparation for skin
US6066124A (en) 1998-11-24 2000-05-23 Caillouette; James C. Control of treatment fluid application to tissue
DE20016131U1 (en) 2000-09-16 2000-11-23 Aesculap AG & Co. KG, 78532 Tuttlingen Applicator for tissue glue
USD436661S1 (en) 1999-05-20 2001-01-23 Melvin P Berry Suppository applicator
US6379342B1 (en) 1999-04-02 2002-04-30 Scion International, Inc. Ampoule for dispensing medication and method of use
US20030068331A1 (en) 2001-06-18 2003-04-10 Alex Battaglia Gum resin as a carrier for topical application of pharmacologically active agents
US6547467B2 (en) 2001-08-29 2003-04-15 Closure Medical Corporation Microapplicators, delivery systems and methods for adhesives and sealants
US6673031B2 (en) 2001-09-25 2004-01-06 Phillip Mark Liquid applicator
JP2004059446A (en) 2002-07-25 2004-02-26 Mitsui Chemicals Inc Alicycic compound and method for producing the same
US20040152766A1 (en) 2001-05-31 2004-08-05 Au-Yeung Steven C.F. Composition comprising demethylcantharidin in combination with platinum-containing anticancer agents and use thereof
US6811342B2 (en) 2000-05-09 2004-11-02 Taiki Corporation, Ltd. System for applying a composition on a surface element
US20040254561A1 (en) 2003-06-13 2004-12-16 Richard Stenton Dual-ended applicator for dispensing two fluids
CN1571795A (en) 2001-10-19 2005-01-26 伊索泰克尼卡股份有限公司 Synthesis of cyclosporin analogs
US20050019418A1 (en) 2003-07-23 2005-01-27 Crutchfield Charles E. Wart treatment
KR20050032154A (en) 2003-10-01 2005-04-07 나건연 Devices for topical application of drugs or chemical compounds
US20050111900A1 (en) 2004-11-30 2005-05-26 Francesca Fazzolari Ampoule and method of use
JP2005187330A (en) 2003-12-24 2005-07-14 Lion Corp Tooth paste product and gel composition selection method
US20050169696A1 (en) 2004-01-22 2005-08-04 Nicolas Albisetti Device and method for applying a product
US20060110415A1 (en) 2004-11-22 2006-05-25 Bioderm Research Topical Delivery System for Cosmetic and Pharmaceutical Agents
US20060116649A1 (en) 2004-11-30 2006-06-01 James Hagele Mini eye drop tip
US20060180613A1 (en) 2003-03-31 2006-08-17 Manesis Nick J Multi-dose liquid dispensing assembly
US20070000566A1 (en) 2005-05-23 2007-01-04 L'oreal Packaging and applicator device for applying a cosmetic or dermatological composition
US20070111954A1 (en) 2003-07-23 2007-05-17 Cuticeuticals, Inc. Apparatus and method of wart treatment
CN101012230A (en) 2007-02-13 2007-08-08 北京世纪博康医药科技有限公司 The preparation technology of sodium cantharidinate
US20070187437A1 (en) 2006-02-10 2007-08-16 Nordson Corporation Dispensing tip for liquid dispensing systems and method of making the same
US20070233020A1 (en) 2006-03-30 2007-10-04 Isaac Hearne Cannula tip eye drop dispenser
US20070233021A1 (en) 2006-04-03 2007-10-04 R.P. Scherer Technologies, Inc. Drop dispenser for the delivery of uniform droplets of viscous liquids
JP2007269693A (en) 2006-03-31 2007-10-18 Kobayashi Pharmaceut Co Ltd Topical skin preparation
US20070275045A1 (en) 2006-02-28 2007-11-29 Evans Robin D Composition for the treatment of warts and molluscum contagiosum
CN101108853A (en) 2007-07-27 2008-01-23 贵州大学 Cantharidin separation and purification method
CN101108854A (en) 2007-07-27 2008-01-23 贵州大学 A kind of cantharidin separation and purification method
JP2008505960A (en) 2004-07-12 2008-02-28 シユワルツ，ローラン Multidrug cancer treatment
CN101161654A (en) 2007-08-16 2008-04-16 广东药学院 Antineoplastic active canthardin derivative and method for preparing same
US20080146674A1 (en) 2006-12-15 2008-06-19 Rosenberg E William Use of gentian violet in treatment of atopic dermatitis
WO2008092068A2 (en) 2007-01-25 2008-07-31 Hyperbranch Medical Technology, Inc. Applicators for multiple component formulations and the like, and methods of use thereof
US20090311028A1 (en) 2006-07-18 2009-12-17 Erich Odermatt Liquid dispenser for medical purposes in the form of an applicator and use of the same
WO2010002476A1 (en) 2008-07-03 2010-01-07 Allelogic Biosciences Corporation Compositions and methods for the protection of nucleophilic groups
CN101798309A (en) 2009-12-04 2010-08-11 南京泽朗医药科技有限公司 Method for preparing cantharidin from cantharides
JP2010235471A (en) 2009-03-30 2010-10-21 Nippon Kenko Kagaku Kenkyu Center:Kk Film-forming formulation
CN102146086A (en) 2011-04-12 2011-08-10 贵州金桥药业有限公司 Preparation method of sodium cantharidate
US20110208136A1 (en) 2007-09-27 2011-08-25 Horst Sollingen Method for applying a liquid medicinal treatment medium to an area to be treated and medicinal product
US20110212033A1 (en) 2007-12-07 2011-09-01 Foamix Ltd. Oil and liquid silicone foamable carriers and formulations
CN102268006A (en) 2011-06-15 2011-12-07 北京联合大学生物化学工程学院 Method for extracting cantharidin from compound enzyme
US20120016320A1 (en) 2010-07-13 2012-01-19 Lin Michael T Method and Device for Liquid Delivery
CN102336765A (en) 2011-10-11 2012-02-01 江苏四环生物股份有限公司 Method for extracting cantharidin from cantharides
US20120148520A1 (en) 2010-12-10 2012-06-14 Michael Strobel Organic Iodine Complex Durable Barrier With Antimicrobial Preparations
CN102526146A (en) 2012-01-13 2012-07-04 苏州大学 Medicament composition containing ginsenoside and cantharidin and application of medicament composition
US20120190658A1 (en) 1999-11-17 2012-07-26 Studin Joel R Method And Composition For The Treatment Of Adverse Skin Conditions
WO2012131238A1 (en) 2011-03-25 2012-10-04 Laboratoires Urgo Composition containing a cellulose, a vegetable oil and a volatile solvent, and use thereof as a dressing
US20120312709A1 (en) 2011-04-12 2012-12-13 Velcera, Inc. Device for storing and dispensing a medicament, and packaging for containing the same
US20130004230A1 (en) 2011-06-04 2013-01-03 Optmed, Inc. Applicator
CN202730045U (en) 2012-08-13 2013-02-13 遵义医学院 Cantharidin separation and purification device
JP2013507367A (en) 2009-10-08 2013-03-04 エムエスデー・コンシユーマー・ケア・インコーポレイテツド Low ether composition and delivery device
CN202920809U (en) 2012-09-27 2013-05-08 合肥诚者成医药科技有限公司 Ointment for treating condyloma acuminata
US20130197075A1 (en) 2011-08-01 2013-08-01 Jacob LEVITT Method of treating acquired perforating dermatosis with cantharidin
US8518076B2 (en) 2007-01-08 2013-08-27 Advanced Medical Solutions (Plymouth) Limited Surgical adhesive applicator
WO2013189841A1 (en) 2012-06-19 2013-12-27 F. Hoffmann-La Roche Ag New bicyclic thiophenylamide compounds
CN103923095A (en) 2014-04-23 2014-07-16 遵义医学院 Demethylated calcium cantharidate
US20140275248A1 (en) 2013-03-14 2014-09-18 Quadex Pharmaceuticals, Llc Treatment of molluscum contagiosum
WO2015027111A1 (en) 2013-08-21 2015-02-26 Verrica Pharmaceuticals, Inc. Compositions, methods and systems for the treatment of cutaneous disorders
US20150328259A1 (en) 2014-04-21 2015-11-19 Aclaris Therapeutics, Inc. Peroxide formulations and methods and applicators for using the same
CN204817029U (en) 2015-06-30 2015-12-02 厦门建霖工业有限公司 Filtration formula health care seedpod of lotus arm
WO2016006693A1 (en) 2014-07-11 2016-01-14 株式会社メニコン Visibility-ensuring material, and device for discharging visibility-ensuring material
WO2016100732A2 (en) 2014-12-17 2016-06-23 Verrica Pharmaceuticals, Inc. Commercially viable synthesis of cantharidin and bioactive cantharidin derivatives
WO2016118633A1 (en) 2015-01-20 2016-07-28 Verrica Pharmaceuticals, Inc. Quantification and preparation of pharmaceutical grade cantharidin
US9480691B1 (en) 2009-01-20 2016-11-01 Hill Dermaceuticals, Inc. Topical liquid containing refined peanut oil for treating skin proliferation or inflammation disorders
USD771250S1 (en) 2015-12-22 2016-11-08 Adhezion Biomedical, Llc Liquid dispenser with an extended tip
USD772407S1 (en) 2015-12-22 2016-11-22 Adhezion Biomedical, Llc Liquid dispenser having a tapered tip
CN106674248A (en) 2016-12-17 2017-05-17 重庆市中药研究院 Novel green environment-friendly synthesis process of cantharidin
US20170305925A1 (en) 2014-10-15 2017-10-26 Lixte Biotechnology, Inc. Process of synthesizing 3-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1] heptane-2-carboxylic acid
USD801830S1 (en) 2016-05-19 2017-11-07 Adhezion Biomedical, Llc Liquid dispenser
WO2018226894A1 (en) 2017-06-06 2018-12-13 Verrica Pharmaceuticals, Inc. Treatment of cutaneous disorders
US10195635B2 (en) 2016-01-25 2019-02-05 Porex Corporation Multicomponent sintered porous liquid applicator nibs
USD868160S1 (en) 2018-03-26 2019-11-26 Robert Lam Multi-nib marker
US20200270269A1 (en) 2017-10-04 2020-08-27 Verrica Pharmaceuticals, Inc. Synthesis of cantharidin
USD900312S1 (en) * 2017-06-15 2020-10-27 Verrica Pharmaceuticals, Inc. Applicator
US20210138214A1 (en) 2017-06-15 2021-05-13 Verrica Pharmaceuticals, Inc. Devices and methods for the treatment of body surface disorders
USD933494S1 (en) * 2018-07-10 2021-10-19 Aptar Radolfzell Gmbh Packaging bottle for liquids
USD938587S1 (en) * 2018-06-11 2021-12-14 Terumo Cardiovascular Systems Corporation Dissector cone for endoscope
US11279165B2 (en) * 2018-04-17 2022-03-22 Crayola Llc Ink-based marking device having a multi-component nib structure
USD947027S1 (en) * 2020-02-11 2022-03-29 B.R. Tenant, Inc. Spout for a container
USD957625S1 (en) * 2020-04-29 2022-07-12 Susan Reynolds Syringe
USD969312S1 (en) * 2010-03-31 2022-11-08 Shl Medical Ag Tubular holder for a medical injector
US11559294B2 (en) * 2018-07-19 2023-01-24 Sanulus Medical, LLC Devices and methods for targeted delivery of a substance

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004093786A2 (en) 2003-04-16 2004-11-04 Corium International Covalent and non-covalent crosslinking of hydrophilic polymers and adhesive compositions prepared therewith

Patent Citations (122)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1744893A (en) 1926-10-02 1930-01-28 George N Hein Hypodermic syringe
CH204207A (en) 1938-03-10 1939-04-30 Richard Graebener Fa Bottle cap.
GB587994A (en) 1945-01-01 1947-05-12 Harry Milman Bickle Improvements relating to stoppers for bottles and other containers
US3393962A (en) 1964-12-04 1968-07-23 Quill Res & Dev Corp Liquid applicator
US3981924A (en) 1974-04-22 1976-09-21 International Flavors & Fragrances Inc. Diels-Alder adduct product
JPS51141863A (en) 1975-06-02 1976-12-07 Nippon Nohyaku Co Ltd Process for preparing organo-phosphoric acid esters
US4157967A (en) 1976-03-25 1979-06-12 Baxter Travenol Laboratories, Inc. Blood filter
US4148874A (en) 1977-06-13 1979-04-10 The Procter & Gamble Company Dermatological compositions
US4299006A (en) 1980-02-19 1981-11-10 Cruz Miguel M Elastic drip guard for paint brushes
US4413154A (en) 1982-09-27 1983-11-01 Mobil Oil Corporation Diels-Alder cyclodimerization over a carbon molecular sieve catalyst
JPH0558914A (en) 1991-08-27 1993-03-09 Shiseido Co Ltd Skin external preparation
JPH05255367A (en) 1992-02-28 1993-10-05 Jitsuei O Production of cantharidin derivative composition and anti-viral agents containing it
US5445462A (en) 1993-08-03 1995-08-29 Medi-Flex Hospital Products, Inc. Liquid applicator
US5702694A (en) 1993-08-17 1997-12-30 Schering-Plough Healthcare Products, Inc. Compositions for treating corns, calluses and warts
US5464855A (en) 1994-08-09 1995-11-07 Warner-Lambert Company Thiophene-2-carboxamidotetrazoles and pharmaceutical use thereof
US5590780A (en) 1995-06-22 1997-01-07 Wheaton Holding, Inc. Unit dose assembly
JPH10114626A (en) 1996-10-07 1998-05-06 L'oreal Sa Use of organopolysilanes with elastomeric properties for use in combination with organic phases in products for nail make-up removal
EP0841059A1 (en) 1996-10-07 1998-05-13 L'oreal Use of a natural elastomeric organopolysiloxan associated with an organic phase in a composition for nail coating removal
JPH11319064A (en) 1998-05-18 1999-11-24 West Agro Inc Improved filming composition for animal skin prophylactic and protective agent
JPH11335303A (en) 1998-05-26 1999-12-07 Lion Corp Method for enhancing bitterness and external preparation for skin
US6066124A (en) 1998-11-24 2000-05-23 Caillouette; James C. Control of treatment fluid application to tissue
US6379342B1 (en) 1999-04-02 2002-04-30 Scion International, Inc. Ampoule for dispensing medication and method of use
USD436661S1 (en) 1999-05-20 2001-01-23 Melvin P Berry Suppository applicator
US20120190658A1 (en) 1999-11-17 2012-07-26 Studin Joel R Method And Composition For The Treatment Of Adverse Skin Conditions
US6811342B2 (en) 2000-05-09 2004-11-02 Taiki Corporation, Ltd. System for applying a composition on a surface element
DE20016131U1 (en) 2000-09-16 2000-11-23 Aesculap AG & Co. KG, 78532 Tuttlingen Applicator for tissue glue
US20040152766A1 (en) 2001-05-31 2004-08-05 Au-Yeung Steven C.F. Composition comprising demethylcantharidin in combination with platinum-containing anticancer agents and use thereof
US20030068331A1 (en) 2001-06-18 2003-04-10 Alex Battaglia Gum resin as a carrier for topical application of pharmacologically active agents
US6547467B2 (en) 2001-08-29 2003-04-15 Closure Medical Corporation Microapplicators, delivery systems and methods for adhesives and sealants
US6673031B2 (en) 2001-09-25 2004-01-06 Phillip Mark Liquid applicator
CN1571795A (en) 2001-10-19 2005-01-26 伊索泰克尼卡股份有限公司 Synthesis of cyclosporin analogs
JP2004059446A (en) 2002-07-25 2004-02-26 Mitsui Chemicals Inc Alicycic compound and method for producing the same
US20060180613A1 (en) 2003-03-31 2006-08-17 Manesis Nick J Multi-dose liquid dispensing assembly
US20040254561A1 (en) 2003-06-13 2004-12-16 Richard Stenton Dual-ended applicator for dispensing two fluids
US20050019418A1 (en) 2003-07-23 2005-01-27 Crutchfield Charles E. Wart treatment
US20070111954A1 (en) 2003-07-23 2007-05-17 Cuticeuticals, Inc. Apparatus and method of wart treatment
KR20050032154A (en) 2003-10-01 2005-04-07 나건연 Devices for topical application of drugs or chemical compounds
JP2005187330A (en) 2003-12-24 2005-07-14 Lion Corp Tooth paste product and gel composition selection method
US20050169696A1 (en) 2004-01-22 2005-08-04 Nicolas Albisetti Device and method for applying a product
JP2008505960A (en) 2004-07-12 2008-02-28 シユワルツ，ローラン Multidrug cancer treatment
US20060110415A1 (en) 2004-11-22 2006-05-25 Bioderm Research Topical Delivery System for Cosmetic and Pharmaceutical Agents
US20060116649A1 (en) 2004-11-30 2006-06-01 James Hagele Mini eye drop tip
US20050111900A1 (en) 2004-11-30 2005-05-26 Francesca Fazzolari Ampoule and method of use
US20070000566A1 (en) 2005-05-23 2007-01-04 L'oreal Packaging and applicator device for applying a cosmetic or dermatological composition
US20070187437A1 (en) 2006-02-10 2007-08-16 Nordson Corporation Dispensing tip for liquid dispensing systems and method of making the same
US20070275045A1 (en) 2006-02-28 2007-11-29 Evans Robin D Composition for the treatment of warts and molluscum contagiosum
US20070233020A1 (en) 2006-03-30 2007-10-04 Isaac Hearne Cannula tip eye drop dispenser
JP2007269693A (en) 2006-03-31 2007-10-18 Kobayashi Pharmaceut Co Ltd Topical skin preparation
US20070233021A1 (en) 2006-04-03 2007-10-04 R.P. Scherer Technologies, Inc. Drop dispenser for the delivery of uniform droplets of viscous liquids
US20090311028A1 (en) 2006-07-18 2009-12-17 Erich Odermatt Liquid dispenser for medical purposes in the form of an applicator and use of the same
US20080146674A1 (en) 2006-12-15 2008-06-19 Rosenberg E William Use of gentian violet in treatment of atopic dermatitis
US8518076B2 (en) 2007-01-08 2013-08-27 Advanced Medical Solutions (Plymouth) Limited Surgical adhesive applicator
JP2010516410A (en) 2007-01-25 2010-05-20 ハイパーブランチ メディカル テクノロジー， インコーポレイテッド Applicator and method of use for multi-component formulations
WO2008092068A2 (en) 2007-01-25 2008-07-31 Hyperbranch Medical Technology, Inc. Applicators for multiple component formulations and the like, and methods of use thereof
US20080195040A1 (en) 2007-01-25 2008-08-14 Hyperbranch Medical Technology, Inc. Applicators for Multiple Component Formulations and the Like, and Methods of Use Thereof
CN101012230A (en) 2007-02-13 2007-08-08 北京世纪博康医药科技有限公司 The preparation technology of sodium cantharidinate
CN101108854A (en) 2007-07-27 2008-01-23 贵州大学 A kind of cantharidin separation and purification method
CN101108853A (en) 2007-07-27 2008-01-23 贵州大学 Cantharidin separation and purification method
CN101161654A (en) 2007-08-16 2008-04-16 广东药学院 Antineoplastic active canthardin derivative and method for preparing same
US20110208136A1 (en) 2007-09-27 2011-08-25 Horst Sollingen Method for applying a liquid medicinal treatment medium to an area to be treated and medicinal product
US20150118164A1 (en) 2007-12-07 2015-04-30 Foamix Pharmaceuticals Ltd. Oil and Liquid Silicone Foamable Carriers and Formulations
US20110212033A1 (en) 2007-12-07 2011-09-01 Foamix Ltd. Oil and liquid silicone foamable carriers and formulations
WO2010002476A1 (en) 2008-07-03 2010-01-07 Allelogic Biosciences Corporation Compositions and methods for the protection of nucleophilic groups
US9480691B1 (en) 2009-01-20 2016-11-01 Hill Dermaceuticals, Inc. Topical liquid containing refined peanut oil for treating skin proliferation or inflammation disorders
JP2010235471A (en) 2009-03-30 2010-10-21 Nippon Kenko Kagaku Kenkyu Center:Kk Film-forming formulation
JP2013507367A (en) 2009-10-08 2013-03-04 エムエスデー・コンシユーマー・ケア・インコーポレイテツド Low ether composition and delivery device
CN101798309A (en) 2009-12-04 2010-08-11 南京泽朗医药科技有限公司 Method for preparing cantharidin from cantharides
USD969312S1 (en) * 2010-03-31 2022-11-08 Shl Medical Ag Tubular holder for a medical injector
US20120016320A1 (en) 2010-07-13 2012-01-19 Lin Michael T Method and Device for Liquid Delivery
US20120148520A1 (en) 2010-12-10 2012-06-14 Michael Strobel Organic Iodine Complex Durable Barrier With Antimicrobial Preparations
WO2012131238A1 (en) 2011-03-25 2012-10-04 Laboratoires Urgo Composition containing a cellulose, a vegetable oil and a volatile solvent, and use thereof as a dressing
US20120312709A1 (en) 2011-04-12 2012-12-13 Velcera, Inc. Device for storing and dispensing a medicament, and packaging for containing the same
CN102146086A (en) 2011-04-12 2011-08-10 贵州金桥药业有限公司 Preparation method of sodium cantharidate
US20130004230A1 (en) 2011-06-04 2013-01-03 Optmed, Inc. Applicator
CN102268006A (en) 2011-06-15 2011-12-07 北京联合大学生物化学工程学院 Method for extracting cantharidin from compound enzyme
US20130197075A1 (en) 2011-08-01 2013-08-01 Jacob LEVITT Method of treating acquired perforating dermatosis with cantharidin
US8871801B2 (en) 2011-08-01 2014-10-28 Jacob LEVITT Method of treating acquired perforating dermatosis with cantharidin
CN102336765A (en) 2011-10-11 2012-02-01 江苏四环生物股份有限公司 Method for extracting cantharidin from cantharides
CN102526146A (en) 2012-01-13 2012-07-04 苏州大学 Medicament composition containing ginsenoside and cantharidin and application of medicament composition
WO2013189841A1 (en) 2012-06-19 2013-12-27 F. Hoffmann-La Roche Ag New bicyclic thiophenylamide compounds
CN202730045U (en) 2012-08-13 2013-02-13 遵义医学院 Cantharidin separation and purification device
CN202920809U (en) 2012-09-27 2013-05-08 合肥诚者成医药科技有限公司 Ointment for treating condyloma acuminata
US20140275248A1 (en) 2013-03-14 2014-09-18 Quadex Pharmaceuticals, Llc Treatment of molluscum contagiosum
CN105636637A (en) 2013-08-21 2016-06-01 威瑞卡制药公司 Compositions, methods and systems for treating skin disorders
US20210386703A1 (en) 2013-08-21 2021-12-16 Verrica Pharmaceuticals Inc. Compositions, methods and systems for the treatment of cutaneous disorders
KR20160045086A (en) 2013-08-21 2016-04-26 베리카 파마슈티컬스, 인코포레이티드 Compositions, methods and systems for the treatment of cutaneous disorders
WO2015027111A1 (en) 2013-08-21 2015-02-26 Verrica Pharmaceuticals, Inc. Compositions, methods and systems for the treatment of cutaneous disorders
JP2016528015A (en) 2013-08-21 2016-09-15 ヴェリカ ファーマシューティカルズ, インコーポレイテッドVerrica Pharmaceuticals, Inc. Compositions, methods and systems for the treatment of skin disorders
US20160193177A1 (en) 2013-08-21 2016-07-07 Varrica Pharmaceuticals. Inc. Compositions, methods and systems for the treatment of cutaneous disorders
US11052064B2 (en) 2013-08-21 2021-07-06 Verrica Pharmaceuticals Inc. Compositions, methods and systems for the treatment of cutaneous disorders
US20150328259A1 (en) 2014-04-21 2015-11-19 Aclaris Therapeutics, Inc. Peroxide formulations and methods and applicators for using the same
KR20170029413A (en) 2014-04-21 2017-03-15 어클라리스 쎄라퓨틱스, 인코포레이티드 Peroxide formulations and methods and applicators for using the same
JP2017513907A (en) 2014-04-21 2017-06-01 アクラリス セラピューティクス、インク． Peroxide formulations and methods and applicators for their use
CN103923095A (en) 2014-04-23 2014-07-16 遵义医学院 Demethylated calcium cantharidate
WO2016006693A1 (en) 2014-07-11 2016-01-14 株式会社メニコン Visibility-ensuring material, and device for discharging visibility-ensuring material
US20170305925A1 (en) 2014-10-15 2017-10-26 Lixte Biotechnology, Inc. Process of synthesizing 3-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1] heptane-2-carboxylic acid
WO2016100732A2 (en) 2014-12-17 2016-06-23 Verrica Pharmaceuticals, Inc. Commercially viable synthesis of cantharidin and bioactive cantharidin derivatives
US10745413B2 (en) 2014-12-17 2020-08-18 Verrica Pharmaceuticals, Inc. Commercially viable synthesis of cantharidin and bioactive cantharidin derivatives
US20190002474A1 (en) 2014-12-17 2019-01-03 Verrica Pharmaceuticals, Inc. Commercially viable synthesis of cantharidin and bioactive cantharidin derivatives
US11168091B2 (en) 2015-01-20 2021-11-09 Verrica Pharmaceuticals Inc. Quantification and preparation of pharmaceutical grade cantharidin
WO2016118633A1 (en) 2015-01-20 2016-07-28 Verrica Pharmaceuticals, Inc. Quantification and preparation of pharmaceutical grade cantharidin
US20190031674A1 (en) 2015-01-20 2019-01-31 Verrica Pharmaceuticals, Inc. Quantification and preparation of pharmaceutical grade cantharidin
CN204817029U (en) 2015-06-30 2015-12-02 厦门建霖工业有限公司 Filtration formula health care seedpod of lotus arm
USD771250S1 (en) 2015-12-22 2016-11-08 Adhezion Biomedical, Llc Liquid dispenser with an extended tip
USD772407S1 (en) 2015-12-22 2016-11-22 Adhezion Biomedical, Llc Liquid dispenser having a tapered tip
US10195635B2 (en) 2016-01-25 2019-02-05 Porex Corporation Multicomponent sintered porous liquid applicator nibs
USD801830S1 (en) 2016-05-19 2017-11-07 Adhezion Biomedical, Llc Liquid dispenser
CN106674248A (en) 2016-12-17 2017-05-17 重庆市中药研究院 Novel green environment-friendly synthesis process of cantharidin
US20210401793A1 (en) 2017-06-06 2021-12-30 Verrica Pharmaceuticals Inc. Treatment of cutaneous disorders
WO2018226894A1 (en) 2017-06-06 2018-12-13 Verrica Pharmaceuticals, Inc. Treatment of cutaneous disorders
US20200155498A1 (en) 2017-06-06 2020-05-21 Verrica Pharmaceuticals, Inc Treatment of cutaneous disorders
US11147790B2 (en) 2017-06-06 2021-10-19 Verrica Pharmaceuticals Inc. Treatment of cutaneous disorders
US20210138214A1 (en) 2017-06-15 2021-05-13 Verrica Pharmaceuticals, Inc. Devices and methods for the treatment of body surface disorders
USD900312S1 (en) * 2017-06-15 2020-10-27 Verrica Pharmaceuticals, Inc. Applicator
US20200270269A1 (en) 2017-10-04 2020-08-27 Verrica Pharmaceuticals, Inc. Synthesis of cantharidin
USD868160S1 (en) 2018-03-26 2019-11-26 Robert Lam Multi-nib marker
US11279165B2 (en) * 2018-04-17 2022-03-22 Crayola Llc Ink-based marking device having a multi-component nib structure
USD938587S1 (en) * 2018-06-11 2021-12-14 Terumo Cardiovascular Systems Corporation Dissector cone for endoscope
USD933494S1 (en) * 2018-07-10 2021-10-19 Aptar Radolfzell Gmbh Packaging bottle for liquids
US11559294B2 (en) * 2018-07-19 2023-01-24 Sanulus Medical, LLC Devices and methods for targeted delivery of a substance
USD947027S1 (en) * 2020-02-11 2022-03-29 B.R. Tenant, Inc. Spout for a container
USD957625S1 (en) * 2020-04-29 2022-07-12 Susan Reynolds Syringe

Non-Patent Citations (69)

* Cited by examiner, † Cited by third party
Title
[No Author Listed] CAS RN 27607-77-8. Entered STN: Nov. 16, 1984. 28 pages.
[No Author Listed] CAS RN 76262-87-8. Entered STN: Nov. 16, 1984. 19 pages.
[No Author Listed] CAS RN 89672-77-5. Entered STN: Nov. 16, 1984. 29 pages.
[No Author Listed] Journal of Organic Chemistry Author Guidelines. Last updated May 5, 2022. 3 pages.
Aitken et al., Fragmentation patterns in the gas-phase pyrolysis of some bi- and tri-cyclic sulfolanes related to the 8-thiabicyclo[4.3.0]non-3-ene 8,8-dioxide ring system . J Chem Soc. Perkin Transactions 1. 1994;16:2301-2308.
Anderson et al., Practical Process Research and Development. 1st Edition. Academic Press. Mar. 20, 2000. 81-111.
Augé et al., Catalysis by Lithium Cation: Lithium Trifluoromethanesulfonate as a Substitute for Lithium Perchlorate in Cycloadditions. Synlett 2000;6:877-9.
Bouacha et al., A theoretical study of the mechanism, stereoselectivity and Lewis acid catalyst on the Diels-Alder cycloaddition between furan and activated alkenes. Tetrahedron Letters. 2013;54:4030-4033.
Braddock et al., Stereochemistry of the Catalysed Diels-Alder Reaction between Cyclopentadiene and Dimethyl Monothionofumarate; Soft versus Hard Lewis Acids. J. Chem. Soc. Chem. Commun. Jan. 1, 1993;16:1244-6. doi: https://doi.org/10.1039/C39930001244.
Brion et al., On the lewis acid catalyzed diels-alder reaction of furan. regio- and stereospecific synthesis of substituted cyclohexenols and cyclohexadienols. Tetrahedron Letters. 1982;23(50):5299-302. https://doi.org/10.1016/S0040-4039(00)85823-2.
Chen et al., Precautions with gentian violet: skin marking made sterile, effective, and economical. Am J Infect Control. Apr. 2009;37(3):244-6. doi: 10.1016/j.ajic.2008.06.005. Epub Oct. 14, 2008.
Chung et al., Sequential Nitromethane Conjugate Addition/Elimination—PD-Catalyzed Allylation of beta-Trifloxy Acrylates. Application to Carbapenem Synthesis. Org Lett. 1999;1(11):1783-1785.
Earle et al., Diels-Alder reactions in ionic liqu1449—. A safe recyclable alternative to lithium perchlorate-diethyl ether mixtures. Green Chem. Feb. 1999; 1:23-25. doi: 10.1039/A808052F.
EP 14837297.2, Date of Mailing Mar. 10, 2017, *Extended European Search Report.
EP 15871116.8, Date of Mailing Oct. 26, 2018, *Extended European Search Report.
EP 16740681.8, Date of Mailing Aug. 8, 2018, *Supplementary European Search Report.
EP 16740681.8, Date of Mailing Dec. 4, 2018, *Extended European Search Report.
Extended European Search Report, mailed Dec. 4, 2018, in connection with EP 16740681.8.
Extended European Search Report, mailed Mar. 10, 2017, in connection with EP 14837297.2.
Extended European Search Report, mailed Oct. 26, 2018, in connection with EP 15871116.8.
Gaul, Part I. Diels-Alder reactions performed in highly polar media. Part II. Reactions of allenylstannanes with in situ generated immonium ions. Dissertation. Indiana University, Bloomington Indiana, 1990. 152 pages.
Harreus et al., 2-Pyrrolidone. Ullmann's Encyclopedia of Industrial Chemistry. 2000. doi: doi: 10.1002/14356007.a22_457.pub2.
Hollis et al., Homogeneous catalysis. Titanium complex [Ti(Cp)2(CF3SO3)2] and zirconium complex [Zr(Cp)2(CF3SO3)2THF], efficient catalysts for the Diels-Alder reaction. Organometallics. Aug. 1, 1992;11(8):2745-8. https://doi.org/10.1021/om00044a004.
Hollis et al., Homogenous Catalysis: Transition Metal Based Lewis Acid Catalysts. Tetrahedron. 1993;49(25):5415-30. doi: https://doi.org/10.1016/S0040-4020(01)87259-8.
Houk et al., On Lewis Acid catalysis of diels-alder reactions. J Am Chem Soc. Jun. 13, 1973;95(12):4094-4096.
Huang, Catalysts for Hetero Diels-Alder Reaction of Imines. Chinese Journal of Organic Chemistry. Oct. 2003;23(10):1064-75.
Hubbard et al., Lewis Acid Catalyzed Diels?Alder Reactions of Highly Hindered Dienophiles. J. Org. Chem. 1998;63(12):4143-4146.
Hunt et al., Why do catalytic quantities of lewis acid generally yield more product than 1.1 equiv in the intramolecular diels-adler reaction with a furan diene? Competitive complexation NMR studies provide an answer. J Am Chem Soc. 1995;117:1049-1056.
International Preliminary Report on Patentability mailed Apr. 16, 2020, in connection with International Application No. PCT/US2018/054373.
International Preliminary Report on Patentability mailed Dec. 26, 2019 in connection with International Application No. PCT/US2018/037808.
International Search Report and Written Opinion, mailed Apr. 3, 2019 in connection with PCT/US2018/054373.
International Search Report and Written Opinion, mailed Nov. 13, 2018, in connection with PCT/US2018/037808.
International Search Report and Written Opinion, mailed Nov. 20, 2014, in connection with PCT/US2014/052184.
International Search Report and Written Opinion, mailed Oct. 22, 2018, in connection with PCT/US2018/036353.
Invitation to Pay Additional Fees, mailed Aug. 27, 2018, in connection with PCT/US2018/O3653.
Invitation to Pay Additional Fees, mailed Dec. 10, 2018, in connection with PCT/US2018/054373.
Invitation to Pay Additional Fees, mailed Sep. 20, 2018, in connection with PCT/US2018/037808.
Kharitonov et al., Synthetic transformations of higher terpenoids: VIII. [4+2]-Cycloaddition reactions of lambertianic acid. Russian J Organic Chem. 2003;39(1):57-74.
Lange et al., Synthesis of 4-carboxy-2-thiabicyclo [3.2.0] Heptan-6-ones via 3-carboxy-2,3-dihydrothiophenes: potential ?-lactamase inhibitors. Tetrahedron Lett. 1985;26(15):1791-1794.
Pagni et al., A chemical, spectroscopic, and theoretical assessment of the lewis acidity of LiClO4 in Diethyl Ether. J. Org Chem. 1993;58:3130-3133.
PCT/US2014/052184, Date of Mailing Nov. 20, 2014, *International Search Report and Written Opinion.
PCT/US2015/066487, Date of Mailing Jul. 14, 2016, *International Search Report and Written Opinion.
PCT/US2015/066487, Date of Mailing Jun. 29, 2017, *International Preliminary Report on Patentability.
PCT/US2016/014139, Date of Mailing Aug. 3, 2017, *International Preliminary Report on Patentability.
PCT/US2016/014139, Date of Mailing Jul. 1, 2016, *International Search Report and Written Opinion.
PCT/US2018/036353, Date of Mailing Aug. 27, 2018, *Invitation to Pay Additional Fees.
PCT/US2018/036353, Date of Mailing Oct. 22, 2018, *International Search Report and Written Opinion.
PCT/US2018/037808, Date of Mailing Dec. 26, 2019, *International Preliminary Report on Patentability.
PCT/US2018/037808, Date of Mailing Nov. 13, 2018, *International Search Report and Written Opinion.
PCT/US2018/037808, Date of Mailing Sep. 20, 2018, *Invitation to Pay Additional Fees.
PCT/US2018/054373, Date of Mailing Apr. 16, 2020, *International Preliminary Report on Patentability.
PCT/US2018/054373, Date of Mailing Apr. 3, 2019, *International Search Report and Written Opinion.
PCT/US2018/054373, Date of Mailing Dec. 10, 2018, *Invitation to Pay Additional Fees.
Prabhakar Reddy et al., Synthesis, cytotoxic activity and structure-activity relationships of hedychenone analogues. Bioorg Med Chem Lett. Apr. 15, 2010;20(8):2525-8. doi: 10.1016/j.bmcl.2010.02.101. Epub Mar. 3, 2010.
Pulce et al., Denatonium Benzoate. Human Toxicol. Jan. 1996;1-12. Accessed 2022 Sep. 12 from <https://www.sciencedirect.com/topics/medicine-and-dentistry/denatonium-benzoate>.
Rossy et al., Aromatization of Dihyrothiophenes. Thiophenesaccharin: A Sweet Surprise. J Org Chem. 1980;45:617-620.
Song et al., Ionic liquids as powerful media in scandium triflate catalysed Diels-Alder reactions: significant rate acceleration, selectivity improvement and easy recycling of catalyst. Chem Commun. 2001;12:1122-3.
Sperry et al., Studies on the Diels-Alder reaction of annulated furans: application to the synthesis of substituted phenanthrenes. Tetrahedron Letters. Apr. 18, 2005;46(16):2789-93. Doi: 10.1016/j.tetlet.2005.02.148.
Supplementary European Search Report, mailed Aug. 8, 2018, in connection with EP 16740681.8.
Tseng et al., Synthesis and Evaluation of Cantharidinimides on Human Cancer Cells. J Exp Clin Med. Oct. 2012;4(5):280-283.
U.S. Appl. No. 14/913,335, filed Feb. 19, 2016, Davidson.
U.S. Appl. No. 15/535,860, filed Jun. 14, 2017, Davidson et al.
U.S. Appl. No. 15/544,669, filed Jul. 19, 2017, Davidson et al.
U.S. Appl. No. 16/619,675, filed Dec. 5, 2019, Welgus et al.
U.S. Appl. No. 16/621,854, filed Dec. 12, 2019, Davidson et al.
U.S. Appl. No. 16/753,660, filed Apr. 3, 2020, Davidson et al.
U.S. Appl. No. 16/995,606, filed Aug. 17, 2020, Davidson et al.
U.S. Appl. No. 29/607,744, filed Jun. 15, 2017, Davidson et al.
White et al., Quinoline Analogues of Ortho-Quinodimethane. Tetrahedron Lett. 1995;36(33):5983-5986.

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12233042B2 (en) 2017-06-06 2025-02-25 Verrica Pharmaceuticals Inc. Treatment of cutaneous disorders
US12290651B2 (en) 2017-06-15 2025-05-06 Verrica Pharmaceuticals Inc. Devices and methods for the treatment of body surface disorders
US12221452B2 (en) 2017-10-04 2025-02-11 Verrica Pharmaceuticals Inc. Synthesis of cantharidin

Also Published As

Publication number Publication date
USD900312S1 (en) 2020-10-27

Similar Documents

Publication Publication Date Title
USD1036656S1 (en) Applicator
USD858349S1 (en) Buckle
USD858168S1 (en) Dispenser
USD801837S1 (en) Portable food scale
USD822233S1 (en) Lamp
USD816975S1 (en) Shoe upper
USD799277S1 (en) Insulating device
USD816621S1 (en) Adjustable bed remote control
USD781558S1 (en) Shoe upper
USD670658S1 (en) Furniture remote control
USD783251S1 (en) Shoe upper
USD786684S1 (en) Bottle
USD793704S1 (en) Shoe upper
USD801667S1 (en) Shoe upper
USD832441S1 (en) Spacer wedge
USD771926S1 (en) Shoe upper
USD861955S1 (en) Light
USD702130S1 (en) Bottle
USD704069S1 (en) Bottle
USD702131S1 (en) Bottle
USD748000S1 (en) Bracelet
USD776439S1 (en) Applicator
USD706109S1 (en) Removable toilet seat handle
USD839483S1 (en) Helmet
USD876635S1 (en) Patient lift

Legal Events

Date Code Title Description
FEPP Fee payment procedure

Free format text: ENTITY STATUS SET TO UNDISCOUNTED (ORIGINAL EVENT CODE: BIG.); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY

FEPP Fee payment procedure

Free format text: ENTITY STATUS SET TO SMALL (ORIGINAL EVENT CODE: SMAL); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY