US8973749B2 - Reagent preparation assembly - Google Patents

Reagent preparation assembly Download PDF

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Publication number
US8973749B2
US8973749B2 US13/805,166 US201113805166A US8973749B2 US 8973749 B2 US8973749 B2 US 8973749B2 US 201113805166 A US201113805166 A US 201113805166A US 8973749 B2 US8973749 B2 US 8973749B2
Authority
US
United States
Prior art keywords
syringe
reaction chamber
reagent
plunger
seal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active, expires
Application number
US13/805,166
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English (en)
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US20130208558A1 (en
Inventor
Timothy Pearcy
James G. Skakoon
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Biolyph LLC
Original Assignee
Biolyph LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biolyph LLC filed Critical Biolyph LLC
Priority to US13/805,166 priority Critical patent/US8973749B2/en
Assigned to BIOLYPH, LLC reassignment BIOLYPH, LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: PEARCY, TIMOTHY, SKAKOON, JAMES G.
Publication of US20130208558A1 publication Critical patent/US20130208558A1/en
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Publication of US8973749B2 publication Critical patent/US8973749B2/en
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Classifications

    • B01F13/0023—
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B01L3/523—Containers specially adapted for storing or dispensing a reagent with means for closing or opening
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • B01F33/50112—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held of the syringe or cartridge type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0672—Integrated piercing tool
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/10—Means to control humidity and/or other gases
    • B01L2300/105—Means to control humidity and/or other gases using desiccants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining
US13/805,166 2010-06-29 2011-06-29 Reagent preparation assembly Active 2031-10-11 US8973749B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US13/805,166 US8973749B2 (en) 2010-06-29 2011-06-29 Reagent preparation assembly

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35963610P 2010-06-29 2010-06-29
US13/805,166 US8973749B2 (en) 2010-06-29 2011-06-29 Reagent preparation assembly
PCT/US2011/042443 WO2012006185A1 (en) 2010-06-29 2011-06-29 Reagent preparation assembly

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/042443 A-371-Of-International WO2012006185A1 (en) 2010-06-29 2011-06-29 Reagent preparation assembly

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US14/597,677 Continuation US10406524B2 (en) 2010-06-29 2015-01-15 Reagent preparation assembly

Publications (2)

Publication Number Publication Date
US20130208558A1 US20130208558A1 (en) 2013-08-15
US8973749B2 true US8973749B2 (en) 2015-03-10

Family

ID=45441528

Family Applications (4)

Application Number Title Priority Date Filing Date
US13/805,166 Active 2031-10-11 US8973749B2 (en) 2010-06-29 2011-06-29 Reagent preparation assembly
US14/597,677 Active 2034-03-12 US10406524B2 (en) 2010-06-29 2015-01-15 Reagent preparation assembly
US16/524,922 Active US10668473B2 (en) 2010-06-29 2019-07-29 Reagent preparation assembly
US16/864,878 Active 2033-04-15 US11819852B2 (en) 2010-06-29 2020-05-01 Reagent preparation assembly

Family Applications After (3)

Application Number Title Priority Date Filing Date
US14/597,677 Active 2034-03-12 US10406524B2 (en) 2010-06-29 2015-01-15 Reagent preparation assembly
US16/524,922 Active US10668473B2 (en) 2010-06-29 2019-07-29 Reagent preparation assembly
US16/864,878 Active 2033-04-15 US11819852B2 (en) 2010-06-29 2020-05-01 Reagent preparation assembly

Country Status (8)

Country Link
US (4) US8973749B2 (de)
EP (1) EP2588404B1 (de)
AU (1) AU2011276396B2 (de)
CA (1) CA2803375C (de)
DK (1) DK2588404T3 (de)
ES (1) ES2669185T3 (de)
NO (1) NO2588404T3 (de)
WO (1) WO2012006185A1 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9889442B2 (en) 2010-11-18 2018-02-13 Biolyph, L.L.C. Reagent preparation and dispensing device
US20180354703A1 (en) * 2017-06-12 2018-12-13 Bio-Techne Corporation Dual chamber storage device
US10406524B2 (en) 2010-06-29 2019-09-10 Biolyph, Llc Reagent preparation assembly

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2905719T3 (es) 2008-05-14 2022-04-11 Biolyph Llc Dispositivo de preparación y dispensación de mezclas de reactivos y métodos asociados
EP2934730B1 (de) * 2012-12-21 2019-09-25 Leica Biosystems Melbourne Pty Ltd Verfahren zur herstellung eines reagens an bord eines instruments
US20210121884A1 (en) * 2012-12-21 2021-04-29 Leica Biosystems Melbourne Pty Ltd Method of producing a reagent on-board an instrument
CN104057511B (zh) * 2014-05-27 2016-03-23 定远县林能木业有限责任公司 一种含纳米二氧化钛的木地板用木材改性处理剂
CN106604774B (zh) * 2014-06-16 2019-10-25 生命技术公司 试剂混合器及流体控制装置
EP3636342B1 (de) 2014-06-17 2021-04-28 Life Technologies Corporation Verfahren zur herstellung einer reagenzpatrone
US20210138471A1 (en) * 2018-07-10 2021-05-13 Biolyph, Llc Reagent storage devices and methods for same
GB2580964B (en) * 2019-02-01 2023-06-07 Dnae Diagnostics Ltd Storage Device
CN115077996A (zh) * 2021-03-15 2022-09-20 富佳生技股份有限公司 移液系统
MX2023003602A (es) 2020-09-30 2023-04-05 Univ Leland Stanford Junior Kit de diagnostico molecular domestico basado en embolo coaxial.
WO2024064702A1 (en) * 2022-09-19 2024-03-28 Biolyph, Llc Reagent cartridges

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US10406524B2 (en) 2019-09-10
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