US8636727B2 - Portable irradiating arrangement - Google Patents

Portable irradiating arrangement Download PDF

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Publication number
US8636727B2
US8636727B2 US12/665,071 US66507108A US8636727B2 US 8636727 B2 US8636727 B2 US 8636727B2 US 66507108 A US66507108 A US 66507108A US 8636727 B2 US8636727 B2 US 8636727B2
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United States
Prior art keywords
probe
inner sleeve
outer sleeve
radiation distributing
sleeve
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Expired - Fee Related, expires
Application number
US12/665,071
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English (en)
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US20100198201A1 (en
Inventor
Alois Bissig
Erich Zurfluh
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Amrita GmbH
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Alplight
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Assigned to ALPLIGHT reassignment ALPLIGHT ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BISSIG, ALOIS, ZURFLUH, ERICH
Publication of US20100198201A1 publication Critical patent/US20100198201A1/en
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Assigned to AMRITA GMBH reassignment AMRITA GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ALPLIGHT AG
Assigned to ALPLIGHT AG reassignment ALPLIGHT AG CHANGE OF NAME AND ADDRESS Assignors: ALPLIGHT
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C1/00Dental machines for boring or cutting ; General features of dental machines or apparatus, e.g. hand-piece design
    • A61C1/0046Dental lasers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/063Radiation therapy using light comprising light transmitting means, e.g. optical fibres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0635Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0644Handheld applicators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/065Light sources therefor
    • A61N2005/0651Diodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0616Skin treatment other than tanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent

Definitions

  • the invention relates to a portable irradiating arrangement with a light source.
  • a laser or a laser diode is preferably employed as the light source.
  • An LED (light-emitting diode) or another white light source or an optical waveguide as well can be used, however.
  • the portable laser arrangement can be used, for example, in the field of medical technology, particularly for the purpose of exposure to light, but it is not limited to applications in this field.
  • Irradiating arrangements are used in many ways in medical technology. Irradiating arrangements with a laser as the light source, so-called laser arrangements, are used, for example, in photodynamic therapy (PDT), photodynamic disinfection (PDD), and in low level light therapy (LLLT). Further, laser arrangements are also used for the cutting of tissue, drilling in or on teeth, for endodontic treatment, in veterinary medicine, for curing of dental fillings, for teeth whitening, and the like. It is advantageous for certain of the enumerated applications to use a portable laser arrangement.
  • PDT photodynamic therapy
  • PDD photodynamic disinfection
  • LLLT low level light therapy
  • laser arrangements are also used for the cutting of tissue, drilling in or on teeth, for endodontic treatment, in veterinary medicine, for curing of dental fillings, for teeth whitening, and the like. It is advantageous for certain of the enumerated applications to use a portable laser arrangement.
  • Prior-art portable laser arrangements with optical powers in the range of more than 1 milliwatt to over 200 milliwatts are frequently designed so that the radiation can emerge unimpeded and can thus represent a danger to the user and the patient.
  • Lasers of this type according to the laser classifications IEC 60825-1/IEC 601-2-22 or the corresponding ANSI standard(s) are assigned to laser class 3B or 4.
  • Assigned to laser class 3B are laser arrangements whose accessible laser radiation is hazardous to the eyes and in special cases to the skin as well, diffuse scattered light not usually being hazardous.
  • Assigned to laser class 4 are laser arrangements whose accessible laser radiation is highly hazardous for the eyes and hazardous for the skin; in this case, diffuse scattered light can also be hazardous and the laser radiation can cause a risk of fire or explosion.
  • protective devices are to be provided for laser arrangements of these laser classes, such as, for example, a safety lock, a safety “interlock” connector, a “laser on” indicator, a “laser ready” indicator, redundant timer electronics, an “emergency stop” switch, etc.
  • a safety lock such as, for example, a safety lock, a safety “interlock” connector, a “laser on” indicator, a “laser ready” indicator, redundant timer electronics, an “emergency stop” switch, etc.
  • the user and patient must wear laser protection glasses, which at times can negatively affect the field of view; the cost of the laser protection glasses increases with the danger of the laser arrangement and thereby with the laser class.
  • additional, often cost-intensive protective devices are therefore necessary.
  • the object of the present invention is to provide a portable irradiating arrangement having a light source, which in the case of a light source made as a laser or laser diode can be assigned to a lower or safer laser class than 3B.
  • the portable irradiating arrangement of the invention in the case of a light source made as a laser or laser diode can be assigned to a laser class of 2M or a lower, safer laser class.
  • the accessible laser radiation is only within the visible range (400 nanometers to 700 nanometers). With a brief radiation duration (up to 0.25 seconds), it is also safe for the eyes as long as no optical instruments, such as loupes or magnifiers, are used.
  • the portable irradiating arrangement of the invention comprises a light source, which is in particular a laser or a laser diode, an outer sleeve, an inner sleeve, and a radiation distributing probe, whereby the inner sleeve is mounted in the outer sleeve and the radiation distributing probe may be attached to one end of the outer sleeve.
  • the end of the outer sleeve to which the radiation distributing probe is to be attached is also called the probe-facing end of the outer sleeve.
  • the irradiating arrangement of the invention is designed in such a way that the light source may be turned on only when the radiation distributing probe is attached to the outer sleeve.
  • the irradiating arrangement of the invention can be used by a user only when the radiation distributing probe is attached to the outer sleeve or to its probe-facing end.
  • the light source can, of course, be a white light source, for example, an LED (light-emitting diode).
  • an optical waveguide, particularly an optical waveguide fiber, may also be used.
  • a spring system which acts on the inner sleeve in the axial direction, so that a first section of the inner sleeve projects at least partially from the probe-facing end of the outer sleeve, whereby the radiation distributing probe is formed in such a way that in the attached state it presses or pushes back the part, projecting from the outer sleeve, of the first section of the inner sleeve against the spring pressure of the spring system at least partially into the outer sleeve.
  • a control element particularly a push button or a touch panel, for turning on the light source is preferably provided on the outer sleeve and the inner sleeve preferably has an opening, whereby the axial distance between the control element and the opening is selected in such a way that the control element can be operationally connected via the opening with the light source only when the radiation distributing probe is attached.
  • a sensor that detects the attachment of the radiation distributing probe is provided in the outer sleeve.
  • the portable irradiating arrangement of the invention can be placed into operation or its light source can be turned on only with an attached radiation distributing probe.
  • the provided protective devices can prove to be less expensive than in the laser arrangements known from the prior art in laser classes 3B and 4 or be totally omitted, so that the use of the portable irradiating arrangement of the invention is cost-effective.
  • a portable irradiating arrangement which comprises a light source, which is in particular a laser or a laser diode or an optical waveguide, an outer sleeve, an inner sleeve, and a radiation distributing probe, whereby the inner sleeve is mounted in the outer sleeve and the radiation distributing probe is attached at one end of the outer sleeve, whereby the inner sleeve is in contact with the radiation distributing probe in such a way that the inner sleeve must be detached from the radiation distributing probe before removal of the radiation distributing probe from the outer sleeve.
  • the inner sleeve in particular prevents the radiation distributing probe from being removed from the outer sleeve by rotation.
  • the light source can be formed as a white light source, for example, as an LED.
  • the inner sleeve in a first, probe-facing section has an outer profile and the radiation distributing probe a matching inner profile, whereby the inner profile sits on the outer profile when the radiation distributing probe is attached.
  • the outer profile of the inner sleeve is preferably made as a hexagonal head and the inner profile of the radiation distributing probe is preferably made as a matching hexagonal socket.
  • the portable irradiating arrangement of the invention is easy to clean and sterilize.
  • the outer sleeve can be cleaned and sterilized in a so-called autoclave.
  • the inner sleeve in which preferably the light source, a current supply for the light source, and electronic components for activating the light source are provided, is protected by the outer sleeve and the radiation distributing probe during the cleaning and sterilization process, because the radiation distributing probe can be removed only after removal of the inner sleeve from the outer sleeve.
  • the extent to which the inner sleeve can be sterilized or autoclaved depends in particular on the design of its electronic components. If this is also necessary for safety reasons, then the inner sleeve can also be removed out of the outer sleeve before sterilization or autoclaving.
  • FIG. 1 shows an illustration of a portable irradiating arrangement of the invention
  • FIG. 2 shows an exploded view of the illustration in FIG. 1 ;
  • FIG. 3 shows a side view of a portable irradiating arrangement of the invention with various radiation distributing probes
  • FIG. 4 shows an illustration of a portable irradiating arrangement of the invention with a removed radiation distributing probe
  • FIG. 5 shows an illustration of a closure device, having a release device, of the portable irradiating arrangement of the invention for the detachment of the radiation distributing probe;
  • FIGS. 6 and 7 show an illustration of an exemplary embodiment of a portable irradiating arrangement of the invention in a back view ( FIG. 6 a ), as a cross section with a removed radiation distributing probe ( FIG. 6 b ), as a detail with a removed radiation distributing probe ( FIG. 6 c ), and as a detail with an attached radiation distributing probe ( FIG. 7 );
  • FIG. 8 shows a detail of a portable irradiating arrangement of the invention with a closure device at its back end
  • FIG. 9 shows a cross section of another exemplary embodiment of a portable irradiating arrangement of the invention with a removed radiation distributing probe ( FIG. 9 a ) and a detail thereof ( FIG. 9 b ).
  • FIGS. 1 and 2 show a portable irradiating arrangement 1 of the invention in an assembled and exploded view.
  • Portable irradiating arrangement 1 comprises an outer sleeve 2 and an inner sleeve 3 , which is arranged removably in outer sleeve 2 .
  • a radiation distributing probe 4 is attached removably at one end of outer sleeve 2 , particularly by means of a plug-in connection, whereby barbs (not shown) may be provided that break off upon rotation. It is also possible, of course, to attach radiation distributing probe 4 to outer sleeve 2 by means of a screw connection.
  • This end of outer sleeve 2 is designated accordingly also as the probe-facing end of the outer sleeve.
  • a closure device 5 is attached removably at the end of outer sleeve 2 , said end that is opposite to said probe-facing end of the outer sleeve.
  • Radiation distributing probe 4 scatters or absorbs the radiation preferably in such a manner that the emerging radiation has a power density that is safe for the skin and eyesight of a user and a patient.
  • Radiation distributing probe 4 may have a light guide 7 (also compare radiation distributing probe 4 . 1 in FIG. 3 ).
  • Other possible embodiments of radiation distributing probe 4 are shown as radiation distributing probe 4 . 2 , 4 . 3 , and 4 . 4 in FIG. 3 .
  • a control element 6 for turning on a light source 14 preferably arranged in inner sleeve 3 of portable irradiating arrangement 1 , (compare FIGS. 6 , 7 , and 9 ) is provided, which is preferably made as a push button, touch panel, switch, and/or button.
  • control element 6 can be formed as acting capacitively, inductively, and/or optically.
  • Control element 6 is preferably arranged in or on outer sleeve 2 .
  • Control element 6 can also be made as a remote control at a distance from irradiating arrangement 1 , e.g., as a foot-operated switch, which during actuation transmits a suitable signal to electronic components 15 of irradiating arrangement 1 , for example, via radio, ultrasound, and/or by means of infrared.
  • Inner sleeve 3 has an opening 17 , whereby with an attached radiation distributing probe 4 control element 6 can be operationally connected via opening 17 with light source 14 arranged in inner sleeve 3 (compare FIGS. 6 , 7 , and 9 ). Light source 14 or portable irradiating arrangement 1 can then be turned on by actuating control element 6 .
  • Inner sleeve 3 is mounted rotation-resistant in outer sleeve 2 , preferably by means of closure device 5 .
  • inner sleeve 3 with a first, probe-facing section 9 at the probe-facing end of outer sleeve 2 projects from said outer sleeve.
  • An outer profile 10 which is preferably formed as a hexagonal head, is provided at least on a part of said first, probe-facing section 9 at its periphery.
  • Radiation distributing probe 4 has an inner profile 20 matching said outer profile 10 (compare FIGS. 6 c and 9 b ), so that inner profile 20 in the case of an attached radiation distributing probe 4 sits on outer profile 10 of first section 9 of inner sleeve 3 . If outer profile 10 of inner sleeve 3 is made as shown as a hexagonal head, then inner profile 20 (compare FIGS. 6 c and 9 b ) of radiation distributing probe 4 is made as a hexagonal socket matching said hexagonal head.
  • an outer profile 10 on a first section 9 of inner sleeve 3 and a matching inner profile 20 on radiation distributing probe 4 represents an anti-rotation protection.
  • inner sleeve 3 is connected via its outer profile 10 to radiation distributing probe 4 or its inner profile 20 , radiation distributing probe 4 cannot be removed from outer sleeve 2 by rotation.
  • inner sleeve 3 must first be detached from radiation distributing probe 4 ; i.e., outer profile 10 of inner sleeve 3 must be detached from inner profile 20 of radiation distributing probe 4 .
  • closure device 5 which is preferably connected via a plug-in and/or screw connection with outer sleeve 2 , is detached from outer sleeve 2 and inner sleeve 3 is removed from outer sleeve 2 .
  • Radiation distributing probe 4 can then be detached from outer sleeve 2 , particularly by a rotatory motion.
  • a sealing ring 8 which can also be called a retaining ring, is provided in the area of outer sleeve 2 , to which radiation distributing probe 4 is attached, to protect inner sleeve 3 from soiling.
  • sealing ring 8 or an additional sealing ring or retaining ring may also be disposed in radiation distributing probe 4 itself.
  • Another sealing ring 26 is preferably provided between closure device 5 and outer sleeve 2 (cf. FIG. 8 ).
  • inner sleeve 3 The anti-rotation protection between inner sleeve 3 and radiation distributing probe 4 assures that radiation distributing probe 4 is not taken off outer sleeve 2 before the removal of inner sleeve 3 from outer sleeve 2 . It is guaranteed in this way that during cleaning and sterilization of portable irradiating arrangement 1 , inner sleeve 3 , if it is sterilizable, does not come into contact with steam and/or other cleaning agents, because inner sleeve 3 preferably contains the light source, current supply for the light source, and other electronic components for controlling the light source. The inner sleeve is protected still further from soiling by sealing ring 8 .
  • Closure device 5 preferably has a release device 11 to release radiation distributing probe 4 from outer sleeve 2 .
  • release device 11 is preferably made U-shaped.
  • radiation distributing probe 4 on its exterior preferably has a longitudinal projection 12 , which is formed in such a way that release device 11 can engage in it to release radiation distributing device 4 .
  • U-shaped release device 11 is placed in or at longitudinal projection 12 . Radiation distributing probe 4 can then be released or “twisted off” from outer sleeve 2 by rotation of closure device 5 .
  • release device 11 by means of this design of release device 11 , an unintentional rolling of irradiating arrangement 1 of the invention on or off a surface, for example, on or off a table, can be prevented and irradiating arrangement 1 can therefore be protected from damage.
  • FIGS. 6 to 9 show cross-sectional views and a back view of portable irradiating arrangement 1 of the invention, whereby in FIG. 6 a the back view shows closure device 5 with U-shaped release device 11 .
  • Light source 14 which is preferably a laser diode, which is preferably assigned a lens, is preferably arranged on the probe-facing side in inner sleeve 3 .
  • a current source 13 which is preferably a battery or an accumulator, preferably two batteries or accumulators, is arranged in inner sleeve 3 .
  • electronic components 15 for controlling or activating light source 14 are provided, which are preferably arranged in the axial direction between current source 13 and light source 14 .
  • Electrical components 15 have a contact 16 for control element 6 .
  • An opening 17 (compare FIG. 2 ), via which the control element 6 can come into contact with or be operationally connected with contact 16 and in this way with electronic components 15 , when radiation distributing probe 4 is attached to outer sleeve 2 , is provided in inner sleeve 3 .
  • Contact 16 is preferably made as a button and control element 6 is preferably made as a push button, so that when control element 6 is pressed button 16 is pressed and in this way an electric circuit for the current supply for light source 14 is closed and light source 14 is supplied with current.
  • a spring system 18 for the spring mounting of inner sleeve 3 is provided.
  • Spring system 18 is preferably provided between closure device 5 and inner sleeve 3 in the axial direction and made as a spring, whereby in addition a sealing plug 19 is arranged removably between spring system 18 and inner sleeve 3 for the independent closing of the end of inner sleeve 3 , said end being opposite to radiation distributing probe 4 (compare FIG. 8 ).
  • inner sleeve 3 can also be closed removably in another manner, so that current source 13 can be replaced if necessary.
  • a spring system 21 is likewise preferably provided between current source 13 and electronic components 15 , to improve the electrical contact between current source 13 and electronic components 15 .
  • An optical waveguide fiber (not shown) may also be used as light source 14 , whereby in this case current source 13 and electronic components 15 can be omitted.
  • Irradiating arrangement 1 is then formed as a fiber-optic handpiece, in which only outer sleeve 2 must be sterilized and not its interior.
  • FIG. 6 c shows the detail labeled with “C” in FIG. 6 b in an enlarged view.
  • Radiation distributing probe 4 is shown separately, i.e., not attached to outer sleeve 2 .
  • Inner sleeve 3 is positioned by spring system 18 in outer sleeve 2 in such a way that the first, probe-facing section 9 projects at least partially from the probe-facing end of the outer sleeve.
  • Outer sleeve 2 preferably has a stop 23 on its inner side for second section 22 of inner sleeve 3 .
  • Second section 22 of inner sleeve 3 is pressed against stop 23 of outer sleeve 2 by spring system 18 , when radiation distributing probe 4 is not mounted on outer sleeve 2 .
  • control element 6 is spaced so far apart or at a distance from opening 17 in inner sleeve 3 in the axial direction (compare FIGS. 2 and 7 ) that it cannot be operationally connected via opening 17 with electronic components 15 or their contact 16 .
  • radiation distributing probe 4 If radiation distributing probe 4 is now placed on outer sleeve 2 , it moves back first section 9 of inner sleeve 3 , at least partially against the spring pressure of spring system 18 , into outer sleeve 2 , so that second section 22 of inner sleeve 3 no longer lies against stop 23 of outer sleeve 2 and control element 6 is now located over opening 17 of inner sleeve 3 and thereby by its actuation can be operationally connected with electronic components 15 or their contact 16 (compare FIG. 7 ).
  • the arrows in FIG. 7 indicate the direction of movement of radiation distributing probe 4 during attachment to outer sleeve 2 of portable irradiating arrangement 1 .
  • FIGS. 9 a and 9 b show the irradiating arrangement illustrated in FIGS. 6 b and 6 c , whereby in addition a sensor 24 is provided, which is arranged in particular in or on outer sleeve 2 .
  • Sensor 24 is formed in such a way that it detects whether a radiation distributing probe 4 is attached to outer sleeve 2 . It is connected via electrical lines, not described in greater detail, to electrical components 15 .
  • Sensor 24 is preferably formed as a pressure sensor, particularly as a button.
  • sensor 24 detects the attachment of a radiation distributing probe 4 , it emits a corresponding signal or changes its position in such a way, if it is formed as a switch or button, that as a result of this the electrical circuit between current source 13 and light source 14 is closed when control element 6 is actuated and thereby portable irradiating arrangement 1 can be turned on by actuating control element 6 .
  • radiation distributing probe 4 preferably has a projection 25 , which presses on sensor 24 , when radiation distributing probe 4 is placed on outer sleeve 2 . In the case of sensor 24 , this results in the detection of the attached radiation distributing probe 4 .
  • Sensor 24 is preferably arranged at the periphery of outer sleeve 2 . Alternatively or in addition, the sensor 24 can also be arranged on the front side of outer sleeve 2 . Particularly in the last case, a projection 25 on radiation distributing probe 4 is not absolutely necessary.
  • only one sensor 24 may also be provided, which is formed as described heretofore.
  • control element 6 can be operationally connected with light source 14 and still in addition the attachment of radiation distributing probe 4 is detected via sensor 24 .

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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dentistry (AREA)
  • Electromagnetism (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Radiation-Therapy Devices (AREA)
  • Laser Surgery Devices (AREA)
US12/665,071 2007-06-29 2008-04-30 Portable irradiating arrangement Expired - Fee Related US8636727B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH10512007 2007-06-29
CH1051/07 2007-06-29
PCT/CH2008/000199 WO2009003295A1 (fr) 2007-06-29 2008-04-30 Dispositif de radiation portable

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US20100198201A1 US20100198201A1 (en) 2010-08-05
US8636727B2 true US8636727B2 (en) 2014-01-28

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EP (1) EP2164567B1 (fr)
CA (1) CA2692895A1 (fr)
WO (1) WO2009003295A1 (fr)

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US20130041357A1 (en) * 2011-08-12 2013-02-14 Ceramoptec Industries Inc. Class 1 laser treatment system
US11759271B2 (en) 2017-04-28 2023-09-19 Stryker Corporation System and method for indicating mapping of console-based surgical systems

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US6887260B1 (en) 1998-11-30 2005-05-03 Light Bioscience, Llc Method and apparatus for acne treatment
US6283956B1 (en) 1998-11-30 2001-09-04 David H. McDaniels Reduction, elimination, or stimulation of hair growth
US20060212025A1 (en) 1998-11-30 2006-09-21 Light Bioscience, Llc Method and apparatus for acne treatment
JP2006522660A (ja) 2003-04-10 2006-10-05 ライト バイオサイエンス,エルエルシー 細胞増殖及び遺伝子発現を調節するためのフォトモジュレーション方法及び装置
US20050149150A1 (en) 2003-07-31 2005-07-07 Light Bioscience L.L.C. System and method for the photodynamic treatment of burns, wounds, and related skin disorders
EP2750619B1 (fr) * 2011-09-02 2019-11-06 Convergent Dental, Inc. Système de préparation dentaire commandé par ordinateur basé sur un laser
DE102012212429A1 (de) * 2012-07-16 2014-01-16 Voco Gmbh Dentalhandgerät, Verfahren und Verwendung desselben zum Aushärten lichthärtbaren Materials

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EP2164567B1 (fr) 2016-01-06

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