US6881220B2 - Method of recapturing a stent - Google Patents
Method of recapturing a stent Download PDFInfo
- Publication number
- US6881220B2 US6881220B2 US10/638,182 US63818203A US6881220B2 US 6881220 B2 US6881220 B2 US 6881220B2 US 63818203 A US63818203 A US 63818203A US 6881220 B2 US6881220 B2 US 6881220B2
- Authority
- US
- United States
- Prior art keywords
- stent
- fluid
- catheter
- recapture
- shape memory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/88—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
- A61F2210/0023—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply
- A61F2210/0042—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply using a fluid, e.g. circulating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
Definitions
- the present invention relates generally to endoluminal devices, and more particularly to stents.
- Stents and similar endoluminal devices have been used to expand a constricted vessel to maintain an open passageway through the vessel in many medical situations, for example, following angioplasty of a coronary artery.
- stents are useful to prevent restenosis of the dilated vessel through proliferation of vascular tissues.
- Stents can also be used to reinforce collapsing structures in the respiratory system, the reproductive system, biliary ducts or any tubular body lumens. Whereas in vascular applications fatty deposits or “plaque” frequently cause the stenosis, in many other body lumens the narrowing or closing may be caused by malignant tissue.
- Fluids have traditionally been used to pressurize the angioplasty balloons used to open restricted vessels.
- the balloons may have a variety of shapes including a coiled form.
- fluid is injected into the balloon to inflate the device and maintain turgidity.
- Shturman U.S. Pat. No. 5,181,911 discloses a perfusion balloon catheter wound into a helically coiled shape with one end attached to a fitting and the other to a syringe for inflating the balloon with fluid.
- the balloon When the balloon is inflated, its coiled form allows blood flow thorough the open center of the structure.
- it is possible to actually have fluid flow within the balloon structure so that the syringe can deliver fluid into the balloon, fluid can flow through the balloon, and fluid can then exit through a second lumen in a catheter attached to the syringe.
- Coiled stents that are connected to a catheter apparatus, as in Wang et al. (U.S. Pat. No. 5,795,318), are used for temporary insertion into a patient.
- Wang et al. discloses a coiled stent of shape-memory thermoplastic tube that can be converted from a relatively narrow diameter to a larger coiled form by heating.
- the narrow diameter coil is mounted at the end of a catheter over a balloon and in a preferred embodiment a resistive heating element runs down the length of the thermoplastic element.
- An electric current is applied to heat the element thereby softening it while the balloon is expanded to enlarge the diameter of the coil.
- the temporary stent has performed its duty, it is again heated and removed while in the softened state.
- the thermoplastic tube is supplied with an additional lumen so that liquid drugs can flow into the stent and delivered through apertures or semi-permeable regions.
- the present invention is an endoluminal coil stent comprising a hollow tube formed into a series of loops or other known stent shapes which initially has a low profile and diameter.
- This structure can be delivered into a patient's vascular system and expanded to full size.
- the present invention to provides a stent that is hollow allowing the passage of fluid.
- the stent has either one or a plurality of passageways for fluid flow.
- the stent is attached to a catheter via a special fitting so that when engaged with the catheter, fluid flows freely from the catheter to the stent with a possible return circuit through the catheter. When disengaged, the fitting prevents leakage from the stent permitting the stent to remain in place in a patient's vasculature.
- This invention provides a way of treating vascular areas affected with malignant growths or experiencing restenosis from smooth muscle cell proliferation, etc.
- the stent is inserted in a small diameter configuration and after being enlarged to a larger diameter, acts as a support device for the areas of restenosis or malignant growth.
- the stent can treat these affected areas in a unique way by flowing radioactive, heated or cryogenic fluids through the stent.
- the present invention also provides a way of delivering drugs to an affected site.
- a stent to accomplish this purpose can be composed of several different materials.
- the stent can formed from a metal or other material with small pores machined or otherwise formed (e.g., with a laser). When such a stent is filed with a drug, that drug slowly disperses through the pores.
- an entire metal tube or portions of the tube could be formed e.g., from sintered metal powder thereby forming a porous structure for drug delivery.
- Another embodiment would alternate a metal tube (for structural stability) with dispensing segments inserted at various intervals. The segments would be perforated to allow seepage of the drug or would be otherwise formed from a porous material.
- Another embodiment employs an expanded polytetrafluoroethylene (PTFE) tube around a support wire or metal tube in the form of a coiled stent so that a hollow passageway is created between the metal and the PTFE. A drug is flowed into this space and slowly dispensed through the porous PTFE.
- PTFE polytetrafluoroethylene
- One embodiment of the hollow stent of the present invention comprises a shape memory metal such as nitinol.
- Shape memory metals are a group of metallic compositions that that have the ability to return to a defined shape or size when subjected to certain thermal or stress conditions. Shape memory metals are generally capable of being deformed at a relatively low temperature and, upon exposure to a relatively higher temperature, return to the defined shape or size they held prior to the deformation. This enables the stent to be inserted into the body in a deformed, smaller state so that it assumes its “remembered” larger shape once it is exposed to a higher temperature (i.e. body temperature or heated fluid) in vivo.
- a higher temperature i.e. body temperature or heated fluid
- the hollow stent has an inlet and an outlet so that a complete fluid path can be created, and fluid can be continually circulated through the stent.
- the inlet and outlet are at opposite ends of the stent.
- two lumens can be connected at a distal end of the structure so that the outlet and inlet are both together at one end.
- Other arrangements can be readily envisioned by one of ordinary skill in the art.
- the stent is inserted into the body while connected to a catheter in a small, deformed state. Once inside the patient's body the stent is advanced to a desired position and expanded to its larger full size. If the stent is composed of shape memory metal, for example, the stent expands from its small-deformed state to its remembered larger state due to the higher body temperature or due to the passage of “hot” fluid through the stent. Subsequently “treatment” fluid (e.g., heated, cryogenic or radioactive) is pumped through the catheter to the stent where it is circulated throughout the stent, treating the adjacent vascular walls. The catheter can either be left in place for a certain period of time or removed, leaving the fluid inside the stent. This would particularly be the case with radioactive fluid or with a porous drug delivery stent.
- treatment fluid e.g., heated, cryogenic or radioactive
- the stent can be removed by reattaching the catheter allowing one to chill and shrink the stent (in the case of a memory alloy).
- the device can readily be used in its tethered form to remove memory alloy stents of the present invention or of prior art design.
- a device of the present invention is inserted into the vasculature to rest within the stent to be removed. Warm fluid is then circulated causing the stent to expand into contact with the memory alloy stent that is already in position. At this point cryogenic (e.g., low temperature) fluid is circulated causing the attached stent and the contacted stent to shrink so that the combination can be readily withdrawn.
- FIG. 1 is a perspective view of a hollow coiled stent.
- FIG. 2 is a perspective view of a valve assembly to be used with FIG. 1 .
- FIG. 3 is a sectional view of the hollow stent tube of FIG. 2 .
- FIG. 4 is a representation of the stent of FIG. 1 in the position for treatment.
- FIG. 5 is a sectional view of a second embodiment of a hollow coiled stent.
- FIG. 6 is a perspective view of a second embodiment of a hollow coiled stent.
- FIG. 7 is a perspective view of a third embodiment of a hollow coiled stent.
- FIG. 8 is a perspective view of a valve assembly to be used with FIG. 6 .
- FIG. 9 is a perspective view of a fourth embodiment of a hollow coiled stent.
- FIG. 10 is a sectional view of the hollow stent tube of FIG. 8 .
- FIGS. 11 ( 11 a , 11 b , and 11 c ) is an illustration of the method detailed in FIG. 12 .
- FIG. 12 is a flow diagram explaining use a stent of the present invention to retrieve a shape memory stent already in place.
- FIG. 1 depicts a preferred embodiment of this invention.
- a medical apparatus 10 comprising an endoluminal stent 20 attached to a delivery catheter 30 by means of a valve assembly 40 .
- endoluminal stent 20 is generally coiled in shape leaving a tubular space down the center of its length.
- the tubing 22 of the stent 20 is preferably composed of a metal material that can be crimped onto a balloon catheter (not shown) for insertion into a body. Once positioned inside of the body at the desired location, the balloon can be inflated, bringing the stent from a compact small size to its enlarged full size thus opening a pathway for blood flow.
- Pathways 26 and 28 have opposite flowing fluid streams and connect at the distal end 24 of stent 20 .
- radioactive, heated or cryogenic liquids can continuously flow through stent 20 for the purpose of killing or preventing proliferation of cells.
- heat or hot is meant temperatures above body temperature.
- cryogenic or “cold” is meant temperatures below body temperature.
- the stent 20 can either remain connected to a delivery catheter 30 for temporary insertion, or be detached for a more permanent insertion. In either case, fluid flow can be circulated throughout stent 20 prior to disconnection.
- fluid passageways connected to the stent 20 are lumens of the delivery catheter so that when the catheter is withdrawn, fluid flow must cease.
- valve 40 may comprise a simple back flow preventer.
- a ball 45 which sits in a ball seat 44 is forced back against a spring 46 and the valve 40 opens for the incoming fluid pathway 28 .
- a similar arrangement allows pressure to open the outgoing fluid pathway 26 .
- a check ball valve is shown only as an example. Flap valves or any of a number of other back flow valve designs well known in the art can be employed. Complex systems in which a bayonet-type attachment automatically opens a valve are also possible.
- the catheter 30 comprises a catheter shaft 32 , which further contains two fluid pathways 34 and 36 as seen in FIG. 2 .
- the valve assembly 40 has small hollow needles 48 that are designed to puncture elastomer diaphragms 25 .
- the catheter 30 is slightly larger in diameter than the stent member 20 so that the catheter tubing wall 32 forms a friction fit over the stent wall 22 . This creates a seal between the catheter 30 , and the stent 20 for fluid delivery and removal.
- the back flow preventer 40 could be on the stent 20 and the diaphragms could be on the catheter 30 .
- stent 20 is inserted into the body to the desired site through the use of a catheter insertion device well known in the art.
- FIG. 4 depicts stent 20 in its enlarged form after it has been inserted into the body at the affected location and expanded.
- Other means of stent expansion other than a balloon catheter are possible.
- the stent 20 is formed from shape memory metal, such as Nitinol, the heat of the body can cause the stent 20 to assume a larger, remembered form. Alternatively, heated fluid can be circulated through the stent to cause it to recover its remembered form.
- a self-expanding stent made of a spring-type alloy can also be employed. In that case the delivery catheter would be equipped with means (e.g., an outer sheath) to keep the stent compressed until it was at the desired location.
- the passageway is enlarged to permit increased blood flow.
- fluids can pass through the interior of tubes 22 of the hollow stent 20 to treat the vascular wall.
- the walls of the vasculature can be treated by running either a radioactive, cryogenic or heated fluid through the stent 20 or by delivering a drug through a stent equipped for drug diffusion (e.g., through holes or a porous region).
- FIG. 5 depicts a second embodiment of the invention.
- the hollow stent 60 has only one fluid pathway 66 , an inlet without an outlet, and is used to deliver drugs to affected areas.
- drugs are delivered through the catheter to the stent 60 .
- Stent 60 can be constructed in various ways to facilitate the delivery of drugs. In one case, as shown in FIG. 6 , the stent 60 is constructed with regions or segments that have pores 64 to allow drug seepage from the tubing 62 . Alternatively, continuously porous metal, porous plastic, or a combination of metal and plastic can be used.
- the perforations 64 or slits in the stent to facilitate drug delivery must be of sufficiently small size to allow the passage of the drug through the entire length of the stent so that all areas can be treated. It will be apparent that pore size can control the rate at which the drug is dispensed. It is possible to cover the pores 64 with semi-permeable membrane to further control and restrict drug outflow. A semi-permeable membrane with inclusion of an osmotic agent with the drug will result in water uptake and more rapid and controlled pressurized delivery of the drug.
- a third embodiment of the invention has a hollow stent 70 containing a single fluid pathway.
- the tubing 72 can be made of any of the materials discussed above, but in this embodiment, the stent 70 has an inlet path 78 that carries the fluid to the distal end 74 of stent 70 where it then runs through the coils.
- a valve 80 connects the stent 70 to catheter 30 .
- FIG. 8 a cross-sectional view of valve 80 . The pressure from the liquid sent through the catheter causes the gate 82 of valve 80 to open to allow the fluid into the inlet path 78 .
- the pressure that forces the opening of gate 82 causes the simultaneous opening of gate 84 , allowing the fluid that is circulated through the stent 70 to exit through pathway 36 of catheter 30 .
- the fluid entering and exiting through catheter 30 must also go through a check ball valve assembly similar to the one shown in FIG. 2 . Again, flaps or other “one way” valve mechanisms can be applied. After all incoming fluid has been delivered to the stent 70 , the absence of pressure causes gate 82 and gate 84 to close, thereby closing valve 80 .
- This design can be used with any of the fluids mentioned above.
- the stent 70 can be used to circulate radioactive or cryogenic fluids for treatment of the vascular walls and can also be perforated for the delivery of drugs.
- a hollow coiled stent 90 is formed from polytetrafluoroethylene (PTFE) 92 .
- PTFE polytetrafluoroethylene
- FIG. 9 a perspective view of this embodiment can be seen.
- the stent 90 consists of a support wire 94 over which PTFE 92 is fitted. The pliable structure resulting is then formed into a coiled stent.
- the PTFE 92 is fitted around the wire 94 so that there is sufficient room to allow the passage of fluid.
- FIG. 10 shows a cross-sectional view of stent 90 , illustrating the pathway 96 created around the support wire 94 to allow the passage of fluid.
- stretched expanded PTFE can be used to create a porous stent to facilitate the delivery of drugs.
- the wire 94 can also be hollow (passageway 95 ) so that the stent 90 can simultaneously deliver drugs and radioactive fluid or temperature regulating fluid.
- FIG. 11 A fifth embodiment of the invention is illustrated in FIG. 11 and described in a flow diagram shown in FIG. 12 .
- This embodiment is a method for recapturing an existing shape memory metal stent already in the body.
- a shape memory metal stent A is inserted into the body in its small, deformed state through the use of an insertion device well known in the art in step 112 .
- the inserted stent A in its deformed state is placed into the center of a memory alloy stent B that is already in an enlarged support position in the body in step 114 .
- the deformed stent A is then enlarged so that it comes in contact with stent B. This can be accomplished in one of two ways.
- Either the stent A may enlarge due to the higher in vivo body temperature in step 115 , or a hot liquid may be pumped through stent A to cause it to expand in step 116 .
- cryogenic liquid may be pumped through stent A so that both stent A and stent B are chilled and either shrink down to their deformed states or become sufficiently relaxed to allow ready removal in step 118 .
- stents A and B are easily removed from the body in step 119 by withdrawing the catheter attached to stent A.
- FIG. 11 a illustrates stent A in its reduced state being inserted into stent A.
- FIG. 11 b shows an enlarged version of stent A contacting stent B.
- a temperature change caused, for example, by fluid circulating through stent A will shrink both stents and enable their removal ( FIG. 11 c ).
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Radiation-Therapy Devices (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Surgical Instruments (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
An endoluminal stent contains a hollow passageway for the circulation of heated and/or cryogenic fluids to recapture a previously implanted shape memory stent. The hollow passageway stent can have one or a plurality of passageways and is configured in a tubular shape with numerous coils, providing an empty tubular lumen through the center of the stent to allow blood flow. The stent is connected to a removable catheter that conducts fluid to the stent. Fluid flow may be regulated by valves incorporated in either the stent and/or the catheter.
Description
This application is a division of application Ser. No. 09/975,743, filed Oct. 11, 2001, now U.S. Pat. No. 6,623,519, which is a division of application Ser. No. 09/321,496, filed May 27, 1999, now U.S. Pat. No. 6,358,276, which claims the benefit of U.S. Provisional Application No. 60/105,768, filed Sep. 30, 1998. This application expressly incorporates by reference the entirety of each of the above-mentioned applications as if fully set forth herein.
The present invention relates generally to endoluminal devices, and more particularly to stents.
Stents and similar endoluminal devices have been used to expand a constricted vessel to maintain an open passageway through the vessel in many medical situations, for example, following angioplasty of a coronary artery. In these situations, stents are useful to prevent restenosis of the dilated vessel through proliferation of vascular tissues. Stents can also be used to reinforce collapsing structures in the respiratory system, the reproductive system, biliary ducts or any tubular body lumens. Whereas in vascular applications fatty deposits or “plaque” frequently cause the stenosis, in many other body lumens the narrowing or closing may be caused by malignant tissue.
Fluids have traditionally been used to pressurize the angioplasty balloons used to open restricted vessels. The balloons may have a variety of shapes including a coiled form. In such a device fluid is injected into the balloon to inflate the device and maintain turgidity. Shturman (U.S. Pat. No. 5,181,911) discloses a perfusion balloon catheter wound into a helically coiled shape with one end attached to a fitting and the other to a syringe for inflating the balloon with fluid. When the balloon is inflated, its coiled form allows blood flow thorough the open center of the structure. At the same time it is possible to actually have fluid flow within the balloon structure so that the syringe can deliver fluid into the balloon, fluid can flow through the balloon, and fluid can then exit through a second lumen in a catheter attached to the syringe.
Coiled stents that are connected to a catheter apparatus, as in Wang et al. (U.S. Pat. No. 5,795,318), are used for temporary insertion into a patient. Wang et al. discloses a coiled stent of shape-memory thermoplastic tube that can be converted from a relatively narrow diameter to a larger coiled form by heating. The narrow diameter coil is mounted at the end of a catheter over a balloon and in a preferred embodiment a resistive heating element runs down the length of the thermoplastic element. An electric current is applied to heat the element thereby softening it while the balloon is expanded to enlarge the diameter of the coil. Upon cooling the enlarged coil hardens and the balloon is withdrawn. After the temporary stent has performed its duty, it is again heated and removed while in the softened state. In one embodiment the thermoplastic tube is supplied with an additional lumen so that liquid drugs can flow into the stent and delivered through apertures or semi-permeable regions.
The attempt to kill or prevent proliferation cells is a common theme in clinical practice. This is generally true in vascular and non-vascular lumens. It is known that ionizing radiation can prevent restenosis and malignant growth. Although the effect of temperature extremes, e.g., cryogenic (cold) or hot temperatures, on cellular activity is not as well researched, it may provide a safer approach to control of tissue proliferation. Among the drawbacks of the prior art coiled balloons is that the balloon material is relatively weak so that expansion and contraction cause the balloon to fail. Failure of a balloon containing radioactive or cryogenic fluids could be catastrophic. It would be desirable to provide a catheter based, minimally invasive device for stenting support that could deliver hot or cryogenic or radioactive fluids or drugs and that would be sturdy and could remain in the body for extended periods of time, detached from the insertion device.
In its simplest embodiment the present invention is an endoluminal coil stent comprising a hollow tube formed into a series of loops or other known stent shapes which initially has a low profile and diameter. This structure can be delivered into a patient's vascular system and expanded to full size. The present invention to provides a stent that is hollow allowing the passage of fluid. The stent has either one or a plurality of passageways for fluid flow. The stent is attached to a catheter via a special fitting so that when engaged with the catheter, fluid flows freely from the catheter to the stent with a possible return circuit through the catheter. When disengaged, the fitting prevents leakage from the stent permitting the stent to remain in place in a patient's vasculature.
This invention provides a way of treating vascular areas affected with malignant growths or experiencing restenosis from smooth muscle cell proliferation, etc. The stent is inserted in a small diameter configuration and after being enlarged to a larger diameter, acts as a support device for the areas of restenosis or malignant growth. In addition, the stent can treat these affected areas in a unique way by flowing radioactive, heated or cryogenic fluids through the stent.
The present invention also provides a way of delivering drugs to an affected site. A stent to accomplish this purpose can be composed of several different materials. For example, the stent can formed from a metal or other material with small pores machined or otherwise formed (e.g., with a laser). When such a stent is filed with a drug, that drug slowly disperses through the pores. Alternatively, an entire metal tube or portions of the tube could be formed e.g., from sintered metal powder thereby forming a porous structure for drug delivery. Another embodiment would alternate a metal tube (for structural stability) with dispensing segments inserted at various intervals. The segments would be perforated to allow seepage of the drug or would be otherwise formed from a porous material. Another embodiment employs an expanded polytetrafluoroethylene (PTFE) tube around a support wire or metal tube in the form of a coiled stent so that a hollow passageway is created between the metal and the PTFE. A drug is flowed into this space and slowly dispensed through the porous PTFE.
One embodiment of the hollow stent of the present invention comprises a shape memory metal such as nitinol. Shape memory metals are a group of metallic compositions that that have the ability to return to a defined shape or size when subjected to certain thermal or stress conditions. Shape memory metals are generally capable of being deformed at a relatively low temperature and, upon exposure to a relatively higher temperature, return to the defined shape or size they held prior to the deformation. This enables the stent to be inserted into the body in a deformed, smaller state so that it assumes its “remembered” larger shape once it is exposed to a higher temperature (i.e. body temperature or heated fluid) in vivo.
Special fittings are incorporated at the ends of the hollow stent. These fittings facilitate the injection and removal of fluid and also allow the stent to be detached from the insertion device to be left in place in a patient. The hollow stent has an inlet and an outlet so that a complete fluid path can be created, and fluid can be continually circulated through the stent. In the simplest configuration the inlet and outlet are at opposite ends of the stent. However, if the stent is equipped with a plurality of lumens, two lumens can be connected at a distal end of the structure so that the outlet and inlet are both together at one end. Other arrangements can be readily envisioned by one of ordinary skill in the art.
The stent is inserted into the body while connected to a catheter in a small, deformed state. Once inside the patient's body the stent is advanced to a desired position and expanded to its larger full size. If the stent is composed of shape memory metal, for example, the stent expands from its small-deformed state to its remembered larger state due to the higher body temperature or due to the passage of “hot” fluid through the stent. Subsequently “treatment” fluid (e.g., heated, cryogenic or radioactive) is pumped through the catheter to the stent where it is circulated throughout the stent, treating the adjacent vascular walls. The catheter can either be left in place for a certain period of time or removed, leaving the fluid inside the stent. This would particularly be the case with radioactive fluid or with a porous drug delivery stent.
The stent can be removed by reattaching the catheter allowing one to chill and shrink the stent (in the case of a memory alloy). Alternatively, the device can readily be used in its tethered form to remove memory alloy stents of the present invention or of prior art design. For this purpose a device of the present invention is inserted into the vasculature to rest within the stent to be removed. Warm fluid is then circulated causing the stent to expand into contact with the memory alloy stent that is already in position. At this point cryogenic (e.g., low temperature) fluid is circulated causing the attached stent and the contacted stent to shrink so that the combination can be readily withdrawn.
These and other embodiments, features and advantages of the present invention will become more apparent to those skilled in the art when taken with reference to the following more detailed description of the invention in conjunction with the accompanying drawings that are first briefly described.
The following detailed description should be read with reference to the drawings, in which like elements in different drawings are identically numbered. The drawings, which are not necessarily to scale, depict selected preferred embodiments and are not intended to limit the scope of the invention. The detailed description illustrates by way of example, not by way of limitation, the principles of the invention. This description will clearly enable one skilled in the art to make and use the invention, and describes several embodiments, adaptations, variations, alternatives and uses of the invention, including what is presently believed to be the best mode of carrying out the invention.
Referring now to the drawings, in which like reference numbers represent similar or identical structures throughout the drawings, FIG. 1 depicts a preferred embodiment of this invention. Pictured in FIG. 1 is a medical apparatus 10 comprising an endoluminal stent 20 attached to a delivery catheter 30 by means of a valve assembly 40. In this representation endoluminal stent 20 is generally coiled in shape leaving a tubular space down the center of its length. Obviously, the principle of a hollow stent can be applied to stents of a zigzag or other construction other than simply coiled. The tubing 22 of the stent 20 is preferably composed of a metal material that can be crimped onto a balloon catheter (not shown) for insertion into a body. Once positioned inside of the body at the desired location, the balloon can be inflated, bringing the stent from a compact small size to its enlarged full size thus opening a pathway for blood flow.
Inside the tubing 22 of stent 20, two fluid pathways exist. These pathways can be seen in the cross sectional view of FIG. 3. Pathways 26 and 28 have opposite flowing fluid streams and connect at the distal end 24 of stent 20. By allowing for opposite streams, radioactive, heated or cryogenic liquids can continuously flow through stent 20 for the purpose of killing or preventing proliferation of cells. By “heated” or “hot” is meant temperatures above body temperature. By “cryogenic” or “cold” is meant temperatures below body temperature. The stent 20 can either remain connected to a delivery catheter 30 for temporary insertion, or be detached for a more permanent insertion. In either case, fluid flow can be circulated throughout stent 20 prior to disconnection. In the simplest design, fluid passageways connected to the stent 20 are lumens of the delivery catheter so that when the catheter is withdrawn, fluid flow must cease.
It is also possible to provide separate flexible tubes that are threaded through the catheter so that the delivery catheter can be withdrawn leaving the relatively smaller fluid delivery tubes (not shown) behind. Preventing leakage of the fluid from the stent 20 after the catheter 30 is disconnected is accomplished through a valve mechanism contained in the catheter 30, or the stent 20 and/or both. In the example illustrated in FIG. 2 rubber or elastomer diaphragms 25 are penetrated by small hollow needles 48 in the valve assembly 40. In addition, the valve 40 may comprise a simple back flow preventer. Thus, when pressure is applied from incoming fluid to the valve assembly 40, a ball 45 which sits in a ball seat 44 is forced back against a spring 46 and the valve 40 opens for the incoming fluid pathway 28. A similar arrangement allows pressure to open the outgoing fluid pathway 26. A check ball valve is shown only as an example. Flap valves or any of a number of other back flow valve designs well known in the art can be employed. Complex systems in which a bayonet-type attachment automatically opens a valve are also possible.
The catheter 30 comprises a catheter shaft 32, which further contains two fluid pathways 34 and 36 as seen in FIG. 2. At the distal end of catheter 30, the valve assembly 40 has small hollow needles 48 that are designed to puncture elastomer diaphragms 25. The catheter 30 is slightly larger in diameter than the stent member 20 so that the catheter tubing wall 32 forms a friction fit over the stent wall 22. This creates a seal between the catheter 30, and the stent 20 for fluid delivery and removal. Upon detaching the catheter 30 leakage from the stent 20 is prevented due to the self-healing properties of the diaphragms 25. Obviously, the back flow preventer 40 could be on the stent 20 and the diaphragms could be on the catheter 30.
As discussed above, stent 20 is inserted into the body to the desired site through the use of a catheter insertion device well known in the art. FIG. 4 depicts stent 20 in its enlarged form after it has been inserted into the body at the affected location and expanded. Other means of stent expansion other than a balloon catheter are possible. If the stent 20 is formed from shape memory metal, such as Nitinol, the heat of the body can cause the stent 20 to assume a larger, remembered form. Alternatively, heated fluid can be circulated through the stent to cause it to recover its remembered form. A self-expanding stent made of a spring-type alloy can also be employed. In that case the delivery catheter would be equipped with means (e.g., an outer sheath) to keep the stent compressed until it was at the desired location.
By increasing the diameter of stent 20 at an affected location, the passageway is enlarged to permit increased blood flow. At the same time, fluids can pass through the interior of tubes 22 of the hollow stent 20 to treat the vascular wall. The walls of the vasculature can be treated by running either a radioactive, cryogenic or heated fluid through the stent 20 or by delivering a drug through a stent equipped for drug diffusion (e.g., through holes or a porous region).
A third embodiment of the invention, FIG. 7 , has a hollow stent 70 containing a single fluid pathway. The tubing 72 can be made of any of the materials discussed above, but in this embodiment, the stent 70 has an inlet path 78 that carries the fluid to the distal end 74 of stent 70 where it then runs through the coils. In this embodiment, a valve 80 connects the stent 70 to catheter 30. FIG. 8 a cross-sectional view of valve 80. The pressure from the liquid sent through the catheter causes the gate 82 of valve 80 to open to allow the fluid into the inlet path 78. The pressure that forces the opening of gate 82 causes the simultaneous opening of gate 84, allowing the fluid that is circulated through the stent 70 to exit through pathway 36 of catheter 30. The fluid entering and exiting through catheter 30 must also go through a check ball valve assembly similar to the one shown in FIG. 2. Again, flaps or other “one way” valve mechanisms can be applied. After all incoming fluid has been delivered to the stent 70, the absence of pressure causes gate 82 and gate 84 to close, thereby closing valve 80. This design can be used with any of the fluids mentioned above. The stent 70 can be used to circulate radioactive or cryogenic fluids for treatment of the vascular walls and can also be perforated for the delivery of drugs.
In a fourth embodiment, a hollow coiled stent 90 is formed from polytetrafluoroethylene (PTFE) 92. In FIG. 9 , a perspective view of this embodiment can be seen. The stent 90 consists of a support wire 94 over which PTFE 92 is fitted. The pliable structure resulting is then formed into a coiled stent. The PTFE 92 is fitted around the wire 94 so that there is sufficient room to allow the passage of fluid. FIG. 10 shows a cross-sectional view of stent 90, illustrating the pathway 96 created around the support wire 94 to allow the passage of fluid. In this embodiment, stretched expanded PTFE can be used to create a porous stent to facilitate the delivery of drugs. The wire 94 can also be hollow (passageway 95) so that the stent 90 can simultaneously deliver drugs and radioactive fluid or temperature regulating fluid.
A fifth embodiment of the invention is illustrated in FIG. 11 and described in a flow diagram shown in FIG. 12. This embodiment is a method for recapturing an existing shape memory metal stent already in the body. With reference to both FIGS. 11 and 12 , a shape memory metal stent A is inserted into the body in its small, deformed state through the use of an insertion device well known in the art in step 112. The inserted stent A in its deformed state is placed into the center of a memory alloy stent B that is already in an enlarged support position in the body in step 114. The deformed stent A is then enlarged so that it comes in contact with stent B. This can be accomplished in one of two ways. Either the stent A may enlarge due to the higher in vivo body temperature in step 115, or a hot liquid may be pumped through stent A to cause it to expand in step 116. Once expanded and in contact with stent B, cryogenic liquid may be pumped through stent A so that both stent A and stent B are chilled and either shrink down to their deformed states or become sufficiently relaxed to allow ready removal in step 118. Once in a small, deformed or relaxed state, stents A and B are easily removed from the body in step 119 by withdrawing the catheter attached to stent A. FIG. 11 a illustrates stent A in its reduced state being inserted into stent A. FIG. 11 b shows an enlarged version of stent A contacting stent B. Thereafter, a temperature change caused, for example, by fluid circulating through stent A will shrink both stents and enable their removal (FIG. 11 c).
Having thus described a preferred embodiment of a hollow endoluminal stent, it should be apparent to those skilled in the art that certain advantages of the within system have been achieved. It should also be appreciated that various modifications, adaptations, and alternative embodiments thereof may be made within the scope and spirit of the present invention. For example, a hollow stent with a coiled, tubular shape has been illustrated, however, many other possibilities exist for the shape and size of the hollow stent. In addition, the passageways are illustrated as round but could take on a variety of other shapes. The described embodiments are to be considered illustrative rather than restrictive. The invention is further defined by the following claims.
Claims (3)
1. A method of recapturing a shape memory stent that has been deployed within a vessel of a patient, wherein a lumen for the flow of blood is created by the deployed shape memory stent, comprising the steps of:
inserting a recapture stent within the shape memory stent, wherein the recapture stent is attached to a catheter, the recapture stent being configured to receive and circulate fluid from the catheter without release of fluid into the vessel;
enlarging the recapture stent to come in contact with the shape memory stent;
cooling the recapture stent thereby reverting the shape memory stent to a smaller or relaxed state whereby the shape memory stent enfolds the recapture stent; and
withdrawing the catheter to remove the recapture stent and shape memory stent.
2. The method according to claim 1 , wherein the enlarging step further comprises the step of circulating heated fluid through the recapture stent.
3. The method according to claim 1 , wherein the cooling step further comprises the step of circulating cryogenic fluid through the recapture stent.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/638,182 US6881220B2 (en) | 1998-09-30 | 2003-08-08 | Method of recapturing a stent |
US11/109,604 US20050187612A1 (en) | 1998-09-30 | 2005-04-19 | Method of recapturing a stent |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10576898P | 1998-09-30 | 1998-09-30 | |
US09/321,496 US6358276B1 (en) | 1998-09-30 | 1999-05-27 | Fluid containing endoluminal stent |
US09/975,743 US6623519B2 (en) | 1998-09-30 | 2001-10-11 | Fluid containing endoluminal stent |
US10/638,182 US6881220B2 (en) | 1998-09-30 | 2003-08-08 | Method of recapturing a stent |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/975,743 Division US6623519B2 (en) | 1998-09-30 | 2001-10-11 | Fluid containing endoluminal stent |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/109,604 Continuation US20050187612A1 (en) | 1998-09-30 | 2005-04-19 | Method of recapturing a stent |
Publications (2)
Publication Number | Publication Date |
---|---|
US20040044394A1 US20040044394A1 (en) | 2004-03-04 |
US6881220B2 true US6881220B2 (en) | 2005-04-19 |
Family
ID=26802921
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/321,496 Expired - Lifetime US6358276B1 (en) | 1998-09-30 | 1999-05-27 | Fluid containing endoluminal stent |
US09/975,743 Expired - Lifetime US6623519B2 (en) | 1998-09-30 | 2001-10-11 | Fluid containing endoluminal stent |
US10/638,182 Expired - Fee Related US6881220B2 (en) | 1998-09-30 | 2003-08-08 | Method of recapturing a stent |
US11/109,604 Abandoned US20050187612A1 (en) | 1998-09-30 | 2005-04-19 | Method of recapturing a stent |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/321,496 Expired - Lifetime US6358276B1 (en) | 1998-09-30 | 1999-05-27 | Fluid containing endoluminal stent |
US09/975,743 Expired - Lifetime US6623519B2 (en) | 1998-09-30 | 2001-10-11 | Fluid containing endoluminal stent |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/109,604 Abandoned US20050187612A1 (en) | 1998-09-30 | 2005-04-19 | Method of recapturing a stent |
Country Status (8)
Country | Link |
---|---|
US (4) | US6358276B1 (en) |
EP (2) | EP1520556B9 (en) |
JP (2) | JP4295436B2 (en) |
CA (1) | CA2345614A1 (en) |
DE (2) | DE69938516T2 (en) |
ES (1) | ES2241325T3 (en) |
MX (1) | MXPA01003280A (en) |
WO (1) | WO2000018327A1 (en) |
Cited By (134)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040147939A1 (en) * | 2001-04-27 | 2004-07-29 | Intek Technology, L.L.C. | Apparatus for delivering, repositioning and/or retrieving self-expanding stents |
US20040193260A1 (en) * | 2001-12-05 | 2004-09-30 | Alferness Clifton A. | Anchor and pull mitral valve device and method |
US20040193246A1 (en) * | 2003-03-25 | 2004-09-30 | Microvention, Inc. | Methods and apparatus for treating aneurysms and other vascular defects |
US20050010240A1 (en) * | 2003-06-05 | 2005-01-13 | Cardiac Dimensions Inc., A Washington Corporation | Device and method for modifying the shape of a body organ |
US20050021121A1 (en) * | 2001-11-01 | 2005-01-27 | Cardiac Dimensions, Inc., A Delaware Corporation | Adjustable height focal tissue deflector |
US20050027351A1 (en) * | 2001-05-14 | 2005-02-03 | Cardiac Dimensions, Inc. A Washington Corporation | Mitral valve regurgitation treatment device and method |
US20050096666A1 (en) * | 2002-12-05 | 2005-05-05 | Gordon Lucas S. | Percutaneous mitral valve annuloplasty delivery system |
US20050119673A1 (en) * | 2002-12-05 | 2005-06-02 | Gordon Lucas S. | Percutaneous mitral valve annuloplasty device delivery method |
US20050137699A1 (en) * | 2003-12-23 | 2005-06-23 | Sadra Medical, A Delaware Corporation | Methods and apparatus for endovascularly replacing a heart valve |
US20050137451A1 (en) * | 2003-12-19 | 2005-06-23 | Cardiac Dimensions, Inc. A Washington Corporation | Tissue shaping device with integral connector and crimp |
US20050137449A1 (en) * | 2003-12-19 | 2005-06-23 | Cardiac Dimensions, Inc. | Tissue shaping device with self-expanding anchors |
US20050171601A1 (en) * | 2000-10-05 | 2005-08-04 | Cosgrove Delos M. | Minimally-invasive annuloplasty repair segment delivery system |
US20050187612A1 (en) * | 1998-09-30 | 2005-08-25 | Bard Peripheral Vascular, Inc. | Method of recapturing a stent |
US20050187619A1 (en) * | 2002-05-08 | 2005-08-25 | Mathis Mark L. | Body lumen device anchor, device and assembly |
US20050216077A1 (en) * | 2002-01-30 | 2005-09-29 | Mathis Mark L | Fixed length anchor and pull mitral valve device and method |
US20050272969A1 (en) * | 2001-12-05 | 2005-12-08 | Alferness Clifton A | Device and method for modifying the shape of a body organ |
US20060173524A1 (en) * | 2003-12-23 | 2006-08-03 | Amr Salahieh | Medical Implant Delivery And Deployment Tool |
US20060211984A1 (en) * | 2003-09-23 | 2006-09-21 | C. R. Bard, Inc. | Implant with shape memory |
US20060271174A1 (en) * | 2003-12-19 | 2006-11-30 | Gregory Nieminen | Mitral Valve Annuloplasty Device with Wide Anchor |
US20060276891A1 (en) * | 2003-12-19 | 2006-12-07 | Gregory Nieminen | Mitral Valve Annuloplasty Device with Twisted Anchor |
US20070055293A1 (en) * | 2001-12-05 | 2007-03-08 | Alferness Clifton A | Device and method for modifying the shape of a body organ |
US20070066879A1 (en) * | 2002-01-30 | 2007-03-22 | Mathis Mark L | Body lumen shaping device with cardiac leads |
US20070135912A1 (en) * | 2003-02-03 | 2007-06-14 | Mathis Mark L | Mitral valve device using conditioned shape memory alloy |
US20070179501A1 (en) * | 2006-01-13 | 2007-08-02 | Paul Firkins | Spinal Rod Support Kit |
US20070191831A1 (en) * | 2006-01-26 | 2007-08-16 | Depuy Spine, Inc. | System and method for cooling a spinal correction device comprising a shape memory material for corrective spinal surgery |
US20070239270A1 (en) * | 2006-04-11 | 2007-10-11 | Mathis Mark L | Mitral Valve Annuloplasty Device with Vena Cava Anchor |
US20080015407A1 (en) * | 2003-05-02 | 2008-01-17 | Mathis Mark L | Device and Method for Modifying the Shape of a Body Organ |
US20090048632A1 (en) * | 2005-10-22 | 2009-02-19 | Paul Firkins | Spinal Support Rod Kit |
US20090222042A1 (en) * | 2005-10-22 | 2009-09-03 | Paul Firkins | Implant Kit For Supporting A Spinal Column |
US20100031793A1 (en) * | 2008-08-11 | 2010-02-11 | Hayner Louis R | Catheter Cutting Tool |
US20100261662A1 (en) * | 2009-04-09 | 2010-10-14 | Endologix, Inc. | Utilization of mural thrombus for local drug delivery into vascular tissue |
US7837728B2 (en) | 2003-12-19 | 2010-11-23 | Cardiac Dimensions, Inc. | Reduced length tissue shaping device |
US7959672B2 (en) | 2003-12-23 | 2011-06-14 | Sadra Medical | Replacement valve and anchor |
US7959666B2 (en) | 2003-12-23 | 2011-06-14 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US7988724B2 (en) | 2003-12-23 | 2011-08-02 | Sadra Medical, Inc. | Systems and methods for delivering a medical implant |
US8048153B2 (en) | 2003-12-23 | 2011-11-01 | Sadra Medical, Inc. | Low profile heart valve and delivery system |
US8052749B2 (en) | 2003-12-23 | 2011-11-08 | Sadra Medical, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US8066757B2 (en) | 2007-10-17 | 2011-11-29 | Mindframe, Inc. | Blood flow restoration and thrombus management methods |
US8088140B2 (en) | 2008-05-19 | 2012-01-03 | Mindframe, Inc. | Blood flow restorative and embolus removal methods |
US8136659B2 (en) | 2005-09-13 | 2012-03-20 | Sadra Medical, Inc. | Two-part package for medical implant |
US8231670B2 (en) | 2003-12-23 | 2012-07-31 | Sadra Medical, Inc. | Repositionable heart valve and method |
US8246678B2 (en) | 2003-12-23 | 2012-08-21 | Sadra Medicl, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8252052B2 (en) | 2003-12-23 | 2012-08-28 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8287584B2 (en) | 2005-11-14 | 2012-10-16 | Sadra Medical, Inc. | Medical implant deployment tool |
US8328868B2 (en) | 2004-11-05 | 2012-12-11 | Sadra Medical, Inc. | Medical devices and delivery systems for delivering medical devices |
US8343213B2 (en) | 2003-12-23 | 2013-01-01 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
US8430914B2 (en) | 2007-10-24 | 2013-04-30 | Depuy Spine, Inc. | Assembly for orthopaedic surgery |
US8545514B2 (en) | 2008-04-11 | 2013-10-01 | Covidien Lp | Monorail neuro-microcatheter for delivery of medical devices to treat stroke, processes and products thereby |
US8579962B2 (en) | 2003-12-23 | 2013-11-12 | Sadra Medical, Inc. | Methods and apparatus for performing valvuloplasty |
US8585713B2 (en) | 2007-10-17 | 2013-11-19 | Covidien Lp | Expandable tip assembly for thrombus management |
US8603160B2 (en) | 2003-12-23 | 2013-12-10 | Sadra Medical, Inc. | Method of using a retrievable heart valve anchor with a sheath |
US8668733B2 (en) | 2004-06-16 | 2014-03-11 | Sadra Medical, Inc. | Everting heart valve |
US8679142B2 (en) | 2008-02-22 | 2014-03-25 | Covidien Lp | Methods and apparatus for flow restoration |
US8728155B2 (en) | 2011-03-21 | 2014-05-20 | Cephea Valve Technologies, Inc. | Disk-based valve apparatus and method for the treatment of valve dysfunction |
US8840663B2 (en) | 2003-12-23 | 2014-09-23 | Sadra Medical, Inc. | Repositionable heart valve method |
US8870948B1 (en) | 2013-07-17 | 2014-10-28 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US8926680B2 (en) | 2007-11-12 | 2015-01-06 | Covidien Lp | Aneurysm neck bridging processes with revascularization systems methods and products thereby |
US8940014B2 (en) | 2011-11-15 | 2015-01-27 | Boston Scientific Scimed, Inc. | Bond between components of a medical device |
US8951243B2 (en) | 2011-12-03 | 2015-02-10 | Boston Scientific Scimed, Inc. | Medical device handle |
US8998976B2 (en) | 2011-07-12 | 2015-04-07 | Boston Scientific Scimed, Inc. | Coupling system for medical devices |
US9005273B2 (en) | 2003-12-23 | 2015-04-14 | Sadra Medical, Inc. | Assessing the location and performance of replacement heart valves |
US9011521B2 (en) | 2003-12-23 | 2015-04-21 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US9023094B2 (en) | 2007-06-25 | 2015-05-05 | Microvention, Inc. | Self-expanding prosthesis |
US9131926B2 (en) | 2011-11-10 | 2015-09-15 | Boston Scientific Scimed, Inc. | Direct connect flush system |
US9198687B2 (en) | 2007-10-17 | 2015-12-01 | Covidien Lp | Acute stroke revascularization/recanalization systems processes and products thereby |
US9220522B2 (en) | 2007-10-17 | 2015-12-29 | Covidien Lp | Embolus removal systems with baskets |
US9277993B2 (en) | 2011-12-20 | 2016-03-08 | Boston Scientific Scimed, Inc. | Medical device delivery systems |
US9415225B2 (en) | 2005-04-25 | 2016-08-16 | Cardiac Pacemakers, Inc. | Method and apparatus for pacing during revascularization |
US9439757B2 (en) | 2014-12-09 | 2016-09-13 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US9510945B2 (en) | 2011-12-20 | 2016-12-06 | Boston Scientific Scimed Inc. | Medical device handle |
US9526609B2 (en) | 2003-12-23 | 2016-12-27 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US9788942B2 (en) | 2015-02-03 | 2017-10-17 | Boston Scientific Scimed Inc. | Prosthetic heart valve having tubular seal |
US20170325938A1 (en) | 2016-05-16 | 2017-11-16 | Boston Scientific Scimed, Inc. | Replacement heart valve implant with invertible leaflets |
US9861477B2 (en) | 2015-01-26 | 2018-01-09 | Boston Scientific Scimed Inc. | Prosthetic heart valve square leaflet-leaflet stitch |
US9901445B2 (en) | 2014-11-21 | 2018-02-27 | Boston Scientific Scimed, Inc. | Valve locking mechanism |
US10080652B2 (en) | 2015-03-13 | 2018-09-25 | Boston Scientific Scimed, Inc. | Prosthetic heart valve having an improved tubular seal |
US10123803B2 (en) | 2007-10-17 | 2018-11-13 | Covidien Lp | Methods of managing neurovascular obstructions |
US10136991B2 (en) | 2015-08-12 | 2018-11-27 | Boston Scientific Scimed Inc. | Replacement heart valve implant |
US10143552B2 (en) | 2015-05-14 | 2018-12-04 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10172708B2 (en) | 2012-01-25 | 2019-01-08 | Boston Scientific Scimed, Inc. | Valve assembly with a bioabsorbable gasket and a replaceable valve implant |
US10179041B2 (en) | 2015-08-12 | 2019-01-15 | Boston Scientific Scimed Icn. | Pinless release mechanism |
US10195392B2 (en) | 2015-07-02 | 2019-02-05 | Boston Scientific Scimed, Inc. | Clip-on catheter |
US10201417B2 (en) | 2015-02-03 | 2019-02-12 | Boston Scientific Scimed Inc. | Prosthetic heart valve having tubular seal |
US10201418B2 (en) | 2010-09-10 | 2019-02-12 | Symetis, SA | Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device |
US10245136B2 (en) | 2016-05-13 | 2019-04-02 | Boston Scientific Scimed Inc. | Containment vessel with implant sheathing guide |
US10258465B2 (en) | 2003-12-23 | 2019-04-16 | Boston Scientific Scimed Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US10278805B2 (en) | 2000-08-18 | 2019-05-07 | Atritech, Inc. | Expandable implant devices for filtering blood flow from atrial appendages |
US10285809B2 (en) | 2015-03-06 | 2019-05-14 | Boston Scientific Scimed Inc. | TAVI anchoring assist device |
US10299922B2 (en) | 2005-12-22 | 2019-05-28 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
US10335277B2 (en) | 2015-07-02 | 2019-07-02 | Boston Scientific Scimed Inc. | Adjustable nosecone |
US10342660B2 (en) | 2016-02-02 | 2019-07-09 | Boston Scientific Inc. | Tensioned sheathing aids |
US10368990B2 (en) | 2017-01-23 | 2019-08-06 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10390953B2 (en) | 2017-03-08 | 2019-08-27 | Cardiac Dimensions Pty. Ltd. | Methods and devices for reducing paravalvular leakage |
US10426617B2 (en) | 2015-03-06 | 2019-10-01 | Boston Scientific Scimed, Inc. | Low profile valve locking mechanism and commissure assembly |
US10449043B2 (en) | 2015-01-16 | 2019-10-22 | Boston Scientific Scimed, Inc. | Displacement based lock and release mechanism |
US10470881B2 (en) | 2015-05-14 | 2019-11-12 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10555809B2 (en) | 2012-06-19 | 2020-02-11 | Boston Scientific Scimed, Inc. | Replacement heart valve |
US10583005B2 (en) | 2016-05-13 | 2020-03-10 | Boston Scientific Scimed, Inc. | Medical device handle |
US10722255B2 (en) | 2008-12-23 | 2020-07-28 | Covidien Lp | Systems and methods for removing obstructive matter from body lumens and treating vascular defects |
US10779940B2 (en) | 2015-09-03 | 2020-09-22 | Boston Scientific Scimed, Inc. | Medical device handle |
US10828154B2 (en) | 2017-06-08 | 2020-11-10 | Boston Scientific Scimed, Inc. | Heart valve implant commissure support structure |
US10849746B2 (en) | 2015-05-14 | 2020-12-01 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
US10898325B2 (en) | 2017-08-01 | 2021-01-26 | Boston Scientific Scimed, Inc. | Medical implant locking mechanism |
US10912933B2 (en) | 2014-08-19 | 2021-02-09 | The Regents Of The University Of California | Implants for localized drug delivery and methods of use thereof |
US10939996B2 (en) | 2017-08-16 | 2021-03-09 | Boston Scientific Scimed, Inc. | Replacement heart valve commissure assembly |
US10993805B2 (en) | 2008-02-26 | 2021-05-04 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US11033257B2 (en) | 2005-01-20 | 2021-06-15 | Cardiac Dimensions Pty. Ltd. | Tissue shaping device |
US11065138B2 (en) | 2016-05-13 | 2021-07-20 | Jenavalve Technology, Inc. | Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system |
US11147668B2 (en) | 2018-02-07 | 2021-10-19 | Boston Scientific Scimed, Inc. | Medical device delivery system with alignment feature |
US11173291B2 (en) | 2020-03-20 | 2021-11-16 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
US11185405B2 (en) | 2013-08-30 | 2021-11-30 | Jenavalve Technology, Inc. | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
US11191641B2 (en) | 2018-01-19 | 2021-12-07 | Boston Scientific Scimed, Inc. | Inductance mode deployment sensors for transcatheter valve system |
US11197754B2 (en) | 2017-01-27 | 2021-12-14 | Jenavalve Technology, Inc. | Heart valve mimicry |
US11229517B2 (en) | 2018-05-15 | 2022-01-25 | Boston Scientific Scimed, Inc. | Replacement heart valve commissure assembly |
US11241312B2 (en) | 2018-12-10 | 2022-02-08 | Boston Scientific Scimed, Inc. | Medical device delivery system including a resistance member |
US11241310B2 (en) | 2018-06-13 | 2022-02-08 | Boston Scientific Scimed, Inc. | Replacement heart valve delivery device |
US11246625B2 (en) | 2018-01-19 | 2022-02-15 | Boston Scientific Scimed, Inc. | Medical device delivery system with feedback loop |
US11278398B2 (en) | 2003-12-23 | 2022-03-22 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US11285002B2 (en) | 2003-12-23 | 2022-03-29 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US11285005B2 (en) | 2006-07-17 | 2022-03-29 | Cardiac Dimensions Pty. Ltd. | Mitral valve annuloplasty device with twisted anchor |
US11331187B2 (en) | 2016-06-17 | 2022-05-17 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
US11337800B2 (en) | 2015-05-01 | 2022-05-24 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
US11338119B2 (en) | 2020-03-20 | 2022-05-24 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
US11337714B2 (en) | 2007-10-17 | 2022-05-24 | Covidien Lp | Restoring blood flow and clot removal during acute ischemic stroke |
US11344526B2 (en) | 2020-03-20 | 2022-05-31 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
US11357624B2 (en) | 2007-04-13 | 2022-06-14 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US11439504B2 (en) | 2019-05-10 | 2022-09-13 | Boston Scientific Scimed, Inc. | Replacement heart valve with improved cusp washout and reduced loading |
US11439732B2 (en) | 2018-02-26 | 2022-09-13 | Boston Scientific Scimed, Inc. | Embedded radiopaque marker in adaptive seal |
US11517431B2 (en) | 2005-01-20 | 2022-12-06 | Jenavalve Technology, Inc. | Catheter system for implantation of prosthetic heart valves |
US11564794B2 (en) | 2008-02-26 | 2023-01-31 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US11589981B2 (en) | 2010-05-25 | 2023-02-28 | Jenavalve Technology, Inc. | Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent |
US11596771B2 (en) | 2020-12-14 | 2023-03-07 | Cardiac Dimensions Pty. Ltd. | Modular pre-loaded medical implants and delivery systems |
US11771544B2 (en) | 2011-05-05 | 2023-10-03 | Symetis Sa | Method and apparatus for compressing/loading stent-valves |
US11938027B2 (en) | 2015-06-09 | 2024-03-26 | Edwards Lifesciences, Llc | Asymmetric mitral annuloplasty band |
Families Citing this family (112)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6063101A (en) * | 1998-11-20 | 2000-05-16 | Precision Vascular Systems, Inc. | Stent apparatus and method |
GB9828696D0 (en) * | 1998-12-29 | 1999-02-17 | Houston J G | Blood-flow tubing |
US6733513B2 (en) | 1999-11-04 | 2004-05-11 | Advanced Bioprosthetic Surfaces, Ltd. | Balloon catheter having metal balloon and method of making same |
US8458879B2 (en) | 2001-07-03 | 2013-06-11 | Advanced Bio Prosthetic Surfaces, Ltd., A Wholly Owned Subsidiary Of Palmaz Scientific, Inc. | Method of fabricating an implantable medical device |
US20050238686A1 (en) * | 1999-12-23 | 2005-10-27 | Advanced Cardiovascular Systems, Inc. | Coating for implantable devices and a method of forming the same |
US6658288B1 (en) * | 2000-05-05 | 2003-12-02 | Endovascular Technologies, Inc. | Apparatus and method for aiding thrombosis through the application of electric potential |
US8252044B1 (en) * | 2000-11-17 | 2012-08-28 | Advanced Bio Prosthestic Surfaces, Ltd. | Device for in vivo delivery of bioactive agents and method of manufacture thereof |
US6974473B2 (en) | 2000-06-30 | 2005-12-13 | Vascular Architects, Inc. | Function-enhanced thrombolytic AV fistula and method |
US10398830B2 (en) | 2000-11-17 | 2019-09-03 | Vactronix Scientific, Llc | Device for in vivo delivery of bioactive agents and method of manufacture thereof |
US9107605B2 (en) | 2000-11-17 | 2015-08-18 | Advanced Bio Prosthetic Surfaces, Ltd., A Wholly Owned Subsidiary Of Palmaz Scientific, Inc. | Device for in vivo delivery of bioactive agents and method of manufacture thereof |
DE50210591D1 (en) | 2001-02-16 | 2007-09-13 | Abbott Lab Vascular Entpr Ltd | IMPLANTS WITH FK506 FOR RESTENOSIS TREATMENT AND PROPHYLAXIS |
AU2002345328A1 (en) | 2001-06-27 | 2003-03-03 | Remon Medical Technologies Ltd. | Method and device for electrochemical formation of therapeutic species in vivo |
AU2003250913A1 (en) * | 2002-07-08 | 2004-01-23 | Abbott Laboratories Vascular Enterprises Limited | Drug eluting stent and methods of manufacture |
JP4995420B2 (en) | 2002-09-26 | 2012-08-08 | アドヴァンスド バイオ プロスセティック サーフェシーズ リミテッド | High strength vacuum deposited Nitinol alloy film, medical thin film graft material, and method of making same. |
US20040088038A1 (en) * | 2002-10-30 | 2004-05-06 | Houdin Dehnad | Porous metal for drug-loaded stents |
US20060271168A1 (en) * | 2002-10-30 | 2006-11-30 | Klaus Kleine | Degradable medical device |
US8435550B2 (en) | 2002-12-16 | 2013-05-07 | Abbot Cardiovascular Systems Inc. | Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device |
US6777647B1 (en) * | 2003-04-16 | 2004-08-17 | Scimed Life Systems, Inc. | Combination laser cutter and cleaner |
US20050234431A1 (en) * | 2004-02-10 | 2005-10-20 | Williams Michael S | Intravascular delivery system for therapeutic agents |
US7488343B2 (en) * | 2003-09-16 | 2009-02-10 | Boston Scientific Scimed, Inc. | Medical devices |
US7803178B2 (en) | 2004-01-30 | 2010-09-28 | Trivascular, Inc. | Inflatable porous implants and methods for drug delivery |
US8137397B2 (en) * | 2004-02-26 | 2012-03-20 | Boston Scientific Scimed, Inc. | Medical devices |
US8361013B2 (en) | 2004-04-19 | 2013-01-29 | The Invention Science Fund I, Llc | Telescoping perfusion management system |
US8353896B2 (en) | 2004-04-19 | 2013-01-15 | The Invention Science Fund I, Llc | Controllable release nasal system |
US8337482B2 (en) | 2004-04-19 | 2012-12-25 | The Invention Science Fund I, Llc | System for perfusion management |
US7850676B2 (en) | 2004-04-19 | 2010-12-14 | The Invention Science Fund I, Llc | System with a reservoir for perfusion management |
US7857767B2 (en) | 2004-04-19 | 2010-12-28 | Invention Science Fund I, Llc | Lumen-traveling device |
US8092549B2 (en) | 2004-09-24 | 2012-01-10 | The Invention Science Fund I, Llc | Ciliated stent-like-system |
US7998060B2 (en) | 2004-04-19 | 2011-08-16 | The Invention Science Fund I, Llc | Lumen-traveling delivery device |
US9011329B2 (en) | 2004-04-19 | 2015-04-21 | Searete Llc | Lumenally-active device |
US8512219B2 (en) | 2004-04-19 | 2013-08-20 | The Invention Science Fund I, Llc | Bioelectromagnetic interface system |
US8024036B2 (en) | 2007-03-19 | 2011-09-20 | The Invention Science Fund I, Llc | Lumen-traveling biological interface device and method of use |
US8177760B2 (en) | 2004-05-12 | 2012-05-15 | C. R. Bard, Inc. | Valved connector |
EP1788988A4 (en) * | 2004-07-27 | 2011-05-11 | Univ Southern California | Percutaneously retrievable stent assembly with fluid draining capability |
US7063720B2 (en) * | 2004-09-14 | 2006-06-20 | The Wallace Enterprises, Inc. | Covered stent with controlled therapeutic agent diffusion |
US7824416B2 (en) * | 2004-10-06 | 2010-11-02 | Boston Scientific Scimed, Inc. | Medical retrieval device |
WO2006086304A1 (en) * | 2005-02-08 | 2006-08-17 | Wilson-Cook Medical Inc. | Self contracting stent |
US8641746B2 (en) * | 2005-05-31 | 2014-02-04 | J.W. Medical Systems Ltd. | In situ stent formation |
US8038704B2 (en) * | 2005-07-27 | 2011-10-18 | Paul S. Sherburne | Stent and other objects removal from a body |
EP1779821A1 (en) * | 2005-10-26 | 2007-05-02 | Etervind AB | Adjustable gastric band |
US8840660B2 (en) | 2006-01-05 | 2014-09-23 | Boston Scientific Scimed, Inc. | Bioerodible endoprostheses and methods of making the same |
US8089029B2 (en) | 2006-02-01 | 2012-01-03 | Boston Scientific Scimed, Inc. | Bioabsorbable metal medical device and method of manufacture |
US20070225799A1 (en) * | 2006-03-24 | 2007-09-27 | Medtronic Vascular, Inc. | Stent, intraluminal stent delivery system, and method of treating a vascular condition |
US8180436B2 (en) | 2006-04-12 | 2012-05-15 | The Invention Science Fund I, Llc | Systems for autofluorescent imaging and target ablation |
US8048150B2 (en) | 2006-04-12 | 2011-11-01 | Boston Scientific Scimed, Inc. | Endoprosthesis having a fiber meshwork disposed thereon |
US20120035437A1 (en) | 2006-04-12 | 2012-02-09 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Navigation of a lumen traveling device toward a target |
WO2007139799A2 (en) * | 2006-05-24 | 2007-12-06 | Mayo Foundation For Medical Education And Research | Devices and methods for crossing chronic total occlusions |
US8052743B2 (en) * | 2006-08-02 | 2011-11-08 | Boston Scientific Scimed, Inc. | Endoprosthesis with three-dimensional disintegration control |
CA2663220A1 (en) | 2006-09-15 | 2008-03-20 | Boston Scientific Limited | Medical devices and methods of making the same |
WO2008034066A1 (en) | 2006-09-15 | 2008-03-20 | Boston Scientific Limited | Bioerodible endoprostheses and methods of making the same |
WO2008034048A2 (en) * | 2006-09-15 | 2008-03-20 | Boston Scientific Limited | Bioerodible endoprosthesis with biostable inorganic layers |
CA2663250A1 (en) | 2006-09-15 | 2008-03-20 | Boston Scientific Limited | Bioerodible endoprostheses and methods of making the same |
CA2663303A1 (en) * | 2006-09-15 | 2008-03-20 | Boston Scientific Limited | Endoprosthesis with adjustable surface features |
ATE530210T1 (en) * | 2006-09-18 | 2011-11-15 | Boston Scient Ltd | ENDOPROSTHESES |
US8002821B2 (en) | 2006-09-18 | 2011-08-23 | Boston Scientific Scimed, Inc. | Bioerodible metallic ENDOPROSTHESES |
US20080097577A1 (en) * | 2006-10-20 | 2008-04-24 | Boston Scientific Scimed, Inc. | Medical device hydrogen surface treatment by electrochemical reduction |
WO2008070130A1 (en) * | 2006-12-04 | 2008-06-12 | Cook Incorporated | Method for loading medical device into a delivery system |
EP2125065B1 (en) | 2006-12-28 | 2010-11-17 | Boston Scientific Limited | Bioerodible endoprostheses and methods of making same |
EP2111193A1 (en) * | 2007-02-13 | 2009-10-28 | Cinvention Ag | Reservoir implants and stents |
US8052745B2 (en) | 2007-09-13 | 2011-11-08 | Boston Scientific Scimed, Inc. | Endoprosthesis |
US8066755B2 (en) | 2007-09-26 | 2011-11-29 | Trivascular, Inc. | System and method of pivoted stent deployment |
US8226701B2 (en) | 2007-09-26 | 2012-07-24 | Trivascular, Inc. | Stent and delivery system for deployment thereof |
US8663309B2 (en) | 2007-09-26 | 2014-03-04 | Trivascular, Inc. | Asymmetric stent apparatus and method |
JP2010540190A (en) | 2007-10-04 | 2010-12-24 | トリバスキュラー・インコーポレイテッド | Modular vascular graft for low profile transdermal delivery |
US20090093871A1 (en) * | 2007-10-08 | 2009-04-09 | Medtronic Vascular, Inc. | Medical Implant With Internal Drug Delivery System |
US20100022951A1 (en) * | 2008-05-19 | 2010-01-28 | Luce, Forward, Hamilton 7 Scripps, Llp | Detachable hub/luer device and processes |
US8328861B2 (en) | 2007-11-16 | 2012-12-11 | Trivascular, Inc. | Delivery system and method for bifurcated graft |
US8083789B2 (en) | 2007-11-16 | 2011-12-27 | Trivascular, Inc. | Securement assembly and method for expandable endovascular device |
US8016880B2 (en) * | 2007-11-16 | 2011-09-13 | Medtronic Vascular, Inc. | Stent having spiral channel for drug delivery |
EP2420213B1 (en) * | 2008-04-23 | 2014-01-15 | Cook Medical Technologies LLC | Method of loading a medical device into a delivery system |
US7998192B2 (en) | 2008-05-09 | 2011-08-16 | Boston Scientific Scimed, Inc. | Endoprostheses |
US8236046B2 (en) | 2008-06-10 | 2012-08-07 | Boston Scientific Scimed, Inc. | Bioerodible endoprosthesis |
DE102008002397A1 (en) * | 2008-06-12 | 2009-12-17 | Biotronik Vi Patent Ag | Implantable device |
US7985252B2 (en) | 2008-07-30 | 2011-07-26 | Boston Scientific Scimed, Inc. | Bioerodible endoprosthesis |
US8382824B2 (en) | 2008-10-03 | 2013-02-26 | Boston Scientific Scimed, Inc. | Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides |
EP2403546A2 (en) | 2009-03-02 | 2012-01-11 | Boston Scientific Scimed, Inc. | Self-buffering medical implants |
US7942917B2 (en) * | 2009-04-17 | 2011-05-17 | Medtronic Vascular, Inc. | Hollow helical stent system |
US9283305B2 (en) | 2009-07-09 | 2016-03-15 | Medtronic Vascular, Inc. | Hollow tubular drug eluting medical devices |
US8678046B2 (en) | 2009-09-20 | 2014-03-25 | Medtronic Vascular, Inc. | Apparatus and methods for loading a drug eluting medical device |
US8828474B2 (en) | 2009-09-20 | 2014-09-09 | Medtronic Vascular, Inc. | Apparatus and methods for loading a drug eluting medical device |
US20110070358A1 (en) | 2009-09-20 | 2011-03-24 | Medtronic Vascular, Inc. | Method of forming hollow tubular drug eluting medical devices |
US8381774B2 (en) * | 2009-09-20 | 2013-02-26 | Medtronic Vascular, Inc. | Methods for loading a drug eluting medical device |
WO2011119573A1 (en) | 2010-03-23 | 2011-09-29 | Boston Scientific Scimed, Inc. | Surface treated bioerodible metal endoprostheses |
US8616040B2 (en) | 2010-09-17 | 2013-12-31 | Medtronic Vascular, Inc. | Method of forming a drug-eluting medical device |
US8632846B2 (en) | 2010-09-17 | 2014-01-21 | Medtronic Vascular, Inc. | Apparatus and methods for loading a drug eluting medical device |
US8333801B2 (en) | 2010-09-17 | 2012-12-18 | Medtronic Vascular, Inc. | Method of Forming a Drug-Eluting Medical Device |
US20150073526A1 (en) * | 2010-10-26 | 2015-03-12 | Bryan W Kluck | Retractable Flow Maintaining Stent |
US20120101560A1 (en) * | 2010-10-26 | 2012-04-26 | Kluck Bryan W | Retractable flow maintaining stent wire |
WO2012071514A1 (en) * | 2010-11-23 | 2012-05-31 | Fred Hutchinson Cancer Research Center | Therapeutic methods for solid delivery |
US8757219B2 (en) | 2011-02-25 | 2014-06-24 | Abbott Cardiovascular Systems Inc. | Suction pump and apparatus for loading material into a stent strut |
US8733408B2 (en) | 2011-02-25 | 2014-05-27 | Abbott Cardiovascular Systems Inc. | Cover sleeve and apparatus for loading material into a stent strut |
US8927047B2 (en) | 2011-02-25 | 2015-01-06 | Abbott Cardiovascular Systems Inc. | Methods of drug loading a hollow stent with a high viscosity formulation |
US8936827B2 (en) | 2011-02-25 | 2015-01-20 | Abbott Cardiovascular Systems Inc. | Methods of loading a hollow stent with a drug or drug formulation |
US20120216908A1 (en) | 2011-02-25 | 2012-08-30 | Abbott Cardiovascular Systems Inc. | Methods Of Drug Loading A Hollow Stent By Immersion |
US9585780B2 (en) | 2011-02-25 | 2017-03-07 | Abbott Cardiovascular Systems Inc. | Pressure chamber and apparatus for loading material into a stent strut |
US9238514B2 (en) | 2011-02-25 | 2016-01-19 | Abbott Cardiovascular Systems Inc. | Vacuum chamber and apparatus for loading material into a stent strut |
US10045881B2 (en) | 2011-09-28 | 2018-08-14 | Zoll Circulation, Inc. | Patient temperature control catheter with helical heat exchange paths |
CN104023760A (en) | 2011-10-28 | 2014-09-03 | 普莱萨格生命科学公司 | Methods for drug delivery |
US8992595B2 (en) | 2012-04-04 | 2015-03-31 | Trivascular, Inc. | Durable stent graft with tapered struts and stable delivery methods and devices |
US9498363B2 (en) | 2012-04-06 | 2016-11-22 | Trivascular, Inc. | Delivery catheter for endovascular device |
US8998977B2 (en) | 2012-04-13 | 2015-04-07 | Medtronic Vascular, Inc. | Hollow drug-filled stent and method of forming hollow drug-filled stent |
US9155645B2 (en) | 2012-06-26 | 2015-10-13 | Abbott Cardiovascular Systems Inc. | Implantable prosthesis with radiopaque particles and method of making same |
US9149375B2 (en) | 2012-06-26 | 2015-10-06 | Abbott Cardiovascular Systems Inc. | Radiopaque drug-filled prosthesis and method of making same |
WO2014151906A1 (en) | 2013-03-14 | 2014-09-25 | Medtronic Vascular Inc. | Method for manufacturing a stent and stent manufactured thereby |
EP2994174A1 (en) | 2013-05-06 | 2016-03-16 | Abbott Cardiovascular Systems Inc. | A hollow stent filled with a therapeutic agent formulation |
WO2015061801A2 (en) * | 2013-10-26 | 2015-04-30 | Accumed Radial Systems Llc | System, apparatus, and method for creating a lumen |
CN103932751B (en) * | 2014-01-23 | 2016-03-30 | 赵雨辰 | Filling administration drainage stent in a kind of body |
US10758406B2 (en) | 2016-12-30 | 2020-09-01 | Zoll Circulation, Inc. | High efficiency heat exchange catheters for control of patient body temperature |
US11060480B2 (en) | 2017-11-14 | 2021-07-13 | The Boeing Company | Sound-attenuating heat exchangers and methods of utilizing the same |
US11525438B2 (en) | 2019-06-28 | 2022-12-13 | The Boeing Company | Shape memory alloy actuators and thermal management systems including the same |
US11168584B2 (en) | 2019-06-28 | 2021-11-09 | The Boeing Company | Thermal management system using shape memory alloy actuator |
US11143170B2 (en) * | 2019-06-28 | 2021-10-12 | The Boeing Company | Shape memory alloy lifting tubes and shape memory alloy actuators including the same |
Citations (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3868956A (en) | 1972-06-05 | 1975-03-04 | Ralph J Alfidi | Vessel implantable appliance and method of implanting it |
US4307723A (en) | 1978-04-07 | 1981-12-29 | Medical Engineering Corporation | Externally grooved ureteral stent |
US4503569A (en) | 1983-03-03 | 1985-03-12 | Dotter Charles T | Transluminally placed expandable graft prosthesis |
US4531933A (en) | 1982-12-07 | 1985-07-30 | C. R. Bard, Inc. | Helical ureteral stent |
US4694838A (en) | 1984-01-30 | 1987-09-22 | Mallinckrodt, Inc. | Loop coronary catheter |
US4706671A (en) | 1985-05-02 | 1987-11-17 | Weinrib Harry P | Catheter with coiled tip |
US4762130A (en) | 1987-01-15 | 1988-08-09 | Thomas J. Fogarty | Catheter with corkscrew-like balloon |
US4795458A (en) | 1987-07-02 | 1989-01-03 | Regan Barrie F | Stent for use following balloon angioplasty |
US4813925A (en) | 1987-04-21 | 1989-03-21 | Medical Engineering Corporation | Spiral ureteral stent |
US4820298A (en) | 1987-11-20 | 1989-04-11 | Leveen Eric G | Internal vascular prosthesis |
US4881939A (en) | 1985-02-19 | 1989-11-21 | The Johns Hopkins University | Implantable helical cuff |
US4887996A (en) | 1987-02-13 | 1989-12-19 | Stig Bengmark | Method and tube equipment for supplying fluid to a space and draining said space |
US4917666A (en) | 1988-11-14 | 1990-04-17 | Medtronic Versaflex, Inc. | Steerable thru-lumen catheter |
US5147370A (en) | 1991-06-12 | 1992-09-15 | Mcnamara Thomas O | Nitinol stent for hollow body conduits |
US5156620A (en) | 1991-02-04 | 1992-10-20 | Pigott John P | Intraluminal graft/stent and balloon catheter for insertion thereof |
US5163928A (en) | 1991-01-07 | 1992-11-17 | Franklin Electronic Publishers, Incorporated | Self-centering catheter |
US5181911A (en) | 1991-04-22 | 1993-01-26 | Shturman Technologies, Inc. | Helical balloon perfusion angioplasty catheter |
US5201901A (en) * | 1987-10-08 | 1993-04-13 | Terumo Kabushiki Kaisha | Expansion unit and apparatus for expanding tubular organ lumen |
US5226888A (en) | 1991-10-25 | 1993-07-13 | Michelle Arney | Coiled, perfusion balloon catheter |
US5370691A (en) | 1993-01-26 | 1994-12-06 | Target Therapeutics, Inc. | Intravascular inflatable stent |
US5380307A (en) | 1992-09-30 | 1995-01-10 | Target Therapeutics, Inc. | Catheter with atraumatic drug delivery tip |
US5441516A (en) | 1994-03-03 | 1995-08-15 | Scimed Lifesystems Inc. | Temporary stent |
US5445594A (en) | 1994-04-05 | 1995-08-29 | Elist; James J. | Implant for expanding penile girth and length |
US5536274A (en) | 1991-02-15 | 1996-07-16 | pfm Produkterfur Die Medizin | Spiral implant for organ pathways |
US5545135A (en) | 1994-10-31 | 1996-08-13 | Boston Scientific Corporation | Perfusion balloon stent |
US5562641A (en) * | 1993-05-28 | 1996-10-08 | A Bromberg & Co. Ltd. | Two way shape memory alloy medical stent |
US5649978A (en) | 1993-05-11 | 1997-07-22 | Target Therapeutics, Inc. | Temporary inflatable intravascular prosthesis |
US5669931A (en) | 1995-03-30 | 1997-09-23 | Target Therapeutics, Inc. | Liquid coils with secondary shape |
US5676685A (en) | 1995-06-22 | 1997-10-14 | Razavi; Ali | Temporary stent |
US5697968A (en) | 1995-08-10 | 1997-12-16 | Aeroquip Corporation | Check valve for intraluminal graft |
US5795318A (en) | 1993-04-30 | 1998-08-18 | Scimed Life Systems, Inc. | Method for delivering drugs to a vascular site |
US5882335A (en) | 1994-09-12 | 1999-03-16 | Cordis Corporation | Retrievable drug delivery stent |
US6050986A (en) | 1997-12-01 | 2000-04-18 | Scimed Life Systems, Inc. | Catheter system for the delivery of a low volume liquid bolus |
US6053900A (en) | 1996-02-16 | 2000-04-25 | Brown; Joe E. | Apparatus and method for delivering diagnostic and therapeutic agents intravascularly |
US6063101A (en) | 1998-11-20 | 2000-05-16 | Precision Vascular Systems, Inc. | Stent apparatus and method |
US6149677A (en) * | 1998-03-31 | 2000-11-21 | Innercool Therapies, Inc. | Circulating fluid hypothermia method |
US6258118B1 (en) * | 1998-11-25 | 2001-07-10 | Israel Aircraft Industries Ltd. | Removable support device |
US6348067B1 (en) | 1998-11-25 | 2002-02-19 | Israel Aircraft Industries Ltd. | Method and system with shape memory heating apparatus for temporarily supporting a tubular organ |
US6413273B1 (en) | 1998-11-25 | 2002-07-02 | Israel Aircraft Industries Ltd. | Method and system for temporarily supporting a tubular organ |
US20020161427A1 (en) * | 2001-04-27 | 2002-10-31 | Dmitry Rabkin | Methods for delivering, repositioning and/or retrieving self-expanding stents |
US6579305B1 (en) * | 1995-12-07 | 2003-06-17 | Medtronic Ave, Inc. | Method and apparatus for delivery deployment and retrieval of a stent comprising shape-memory material |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3765032A (en) * | 1972-09-27 | 1973-10-16 | J Palma | Implant |
US3868856A (en) * | 1973-04-25 | 1975-03-04 | Nasa | Instrumentation for measurement of air-craft noise and sonic boom |
US4496350A (en) * | 1980-04-08 | 1985-01-29 | Renal Systems, Inc. | Blood access device |
US4496349A (en) * | 1981-05-08 | 1985-01-29 | Renal Systems, Inc. | Percutaneous implant |
US5013304A (en) * | 1989-02-22 | 1991-05-07 | Bfd, Inc. | Intravascular catheter assembly |
US5158620A (en) * | 1989-06-08 | 1992-10-27 | Composite Materials Technology, Inc. | Superconductor and process of manufacture |
EP0441516B1 (en) * | 1990-02-08 | 1995-03-29 | Howmedica Inc. | Inflatable stent |
US5624392A (en) * | 1990-05-11 | 1997-04-29 | Saab; Mark A. | Heat transfer catheters and methods of making and using same |
JPH04314438A (en) * | 1991-01-14 | 1992-11-05 | Olympus Optical Co Ltd | Implanted device for medical treatment |
US5167239A (en) * | 1991-05-30 | 1992-12-01 | Endomedix Corporation | Anchorable guidewire |
US5256146A (en) * | 1991-10-11 | 1993-10-26 | W. D. Ensminger | Vascular catheterization system with catheter anchoring feature |
US5342387A (en) * | 1992-06-18 | 1994-08-30 | American Biomed, Inc. | Artificial support for a blood vessel |
US5523092A (en) * | 1993-04-14 | 1996-06-04 | Emory University | Device for local drug delivery and methods for using the same |
JPH08509642A (en) * | 1993-04-28 | 1996-10-15 | フォーカル,インコーポレイテッド | Device and method for intraluminal photothermoforming |
US5534024A (en) * | 1994-11-04 | 1996-07-09 | Aeroquip Corporation | Intraluminal stenting graft |
EP0812165A4 (en) | 1995-02-27 | 2000-01-19 | Instent Inc | Hollow stent |
US5871537A (en) * | 1996-02-13 | 1999-02-16 | Scimed Life Systems, Inc. | Endovascular apparatus |
ZA9710342B (en) * | 1996-11-25 | 1998-06-10 | Alza Corp | Directional drug delivery stent and method of use. |
EP2298241A3 (en) * | 1996-12-03 | 2011-11-02 | Atrium Medical Corporation | Multi-stage prothesis |
US6383210B1 (en) * | 2000-06-02 | 2002-05-07 | Innercool Therapies, Inc. | Method for determining the effective thermal mass of a body or organ using cooling catheter |
JP2003526392A (en) * | 1998-09-29 | 2003-09-09 | シー・アール・バード・インク | Drug supply system |
US6358276B1 (en) * | 1998-09-30 | 2002-03-19 | Impra, Inc. | Fluid containing endoluminal stent |
JP4299973B2 (en) * | 1999-05-20 | 2009-07-22 | ボストン サイエンティフィック リミテッド | Stent delivery system with a shrink stabilizer |
-
1999
- 1999-05-27 US US09/321,496 patent/US6358276B1/en not_active Expired - Lifetime
- 1999-09-30 ES ES99948521T patent/ES2241325T3/en not_active Expired - Lifetime
- 1999-09-30 DE DE69938516T patent/DE69938516T2/en not_active Expired - Lifetime
- 1999-09-30 WO PCT/US1999/022806 patent/WO2000018327A1/en active IP Right Grant
- 1999-09-30 MX MXPA01003280A patent/MXPA01003280A/en active IP Right Grant
- 1999-09-30 JP JP2000571850A patent/JP4295436B2/en not_active Expired - Fee Related
- 1999-09-30 EP EP04029223A patent/EP1520556B9/en not_active Expired - Lifetime
- 1999-09-30 DE DE69924856T patent/DE69924856T2/en not_active Expired - Lifetime
- 1999-09-30 CA CA002345614A patent/CA2345614A1/en not_active Abandoned
- 1999-09-30 EP EP99948521A patent/EP1117347B1/en not_active Expired - Lifetime
-
2001
- 2001-10-11 US US09/975,743 patent/US6623519B2/en not_active Expired - Lifetime
-
2003
- 2003-08-08 US US10/638,182 patent/US6881220B2/en not_active Expired - Fee Related
-
2005
- 2005-04-19 US US11/109,604 patent/US20050187612A1/en not_active Abandoned
-
2008
- 2008-08-08 JP JP2008205196A patent/JP4805316B2/en not_active Expired - Fee Related
Patent Citations (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3868956A (en) | 1972-06-05 | 1975-03-04 | Ralph J Alfidi | Vessel implantable appliance and method of implanting it |
US4307723A (en) | 1978-04-07 | 1981-12-29 | Medical Engineering Corporation | Externally grooved ureteral stent |
US4531933A (en) | 1982-12-07 | 1985-07-30 | C. R. Bard, Inc. | Helical ureteral stent |
US4503569A (en) | 1983-03-03 | 1985-03-12 | Dotter Charles T | Transluminally placed expandable graft prosthesis |
US4694838A (en) | 1984-01-30 | 1987-09-22 | Mallinckrodt, Inc. | Loop coronary catheter |
US4881939A (en) | 1985-02-19 | 1989-11-21 | The Johns Hopkins University | Implantable helical cuff |
US4706671A (en) | 1985-05-02 | 1987-11-17 | Weinrib Harry P | Catheter with coiled tip |
US4762130A (en) | 1987-01-15 | 1988-08-09 | Thomas J. Fogarty | Catheter with corkscrew-like balloon |
US4887996A (en) | 1987-02-13 | 1989-12-19 | Stig Bengmark | Method and tube equipment for supplying fluid to a space and draining said space |
US4813925A (en) | 1987-04-21 | 1989-03-21 | Medical Engineering Corporation | Spiral ureteral stent |
US4795458A (en) | 1987-07-02 | 1989-01-03 | Regan Barrie F | Stent for use following balloon angioplasty |
US5201901A (en) * | 1987-10-08 | 1993-04-13 | Terumo Kabushiki Kaisha | Expansion unit and apparatus for expanding tubular organ lumen |
US4820298A (en) | 1987-11-20 | 1989-04-11 | Leveen Eric G | Internal vascular prosthesis |
US4917666A (en) | 1988-11-14 | 1990-04-17 | Medtronic Versaflex, Inc. | Steerable thru-lumen catheter |
US5163928A (en) | 1991-01-07 | 1992-11-17 | Franklin Electronic Publishers, Incorporated | Self-centering catheter |
US5156620A (en) | 1991-02-04 | 1992-10-20 | Pigott John P | Intraluminal graft/stent and balloon catheter for insertion thereof |
US5536274A (en) | 1991-02-15 | 1996-07-16 | pfm Produkterfur Die Medizin | Spiral implant for organ pathways |
US5181911A (en) | 1991-04-22 | 1993-01-26 | Shturman Technologies, Inc. | Helical balloon perfusion angioplasty catheter |
US5147370A (en) | 1991-06-12 | 1992-09-15 | Mcnamara Thomas O | Nitinol stent for hollow body conduits |
US5226888A (en) | 1991-10-25 | 1993-07-13 | Michelle Arney | Coiled, perfusion balloon catheter |
US5380307A (en) | 1992-09-30 | 1995-01-10 | Target Therapeutics, Inc. | Catheter with atraumatic drug delivery tip |
US5370691A (en) | 1993-01-26 | 1994-12-06 | Target Therapeutics, Inc. | Intravascular inflatable stent |
US5795318A (en) | 1993-04-30 | 1998-08-18 | Scimed Life Systems, Inc. | Method for delivering drugs to a vascular site |
US5649978A (en) | 1993-05-11 | 1997-07-22 | Target Therapeutics, Inc. | Temporary inflatable intravascular prosthesis |
US5562641A (en) * | 1993-05-28 | 1996-10-08 | A Bromberg & Co. Ltd. | Two way shape memory alloy medical stent |
US5441516A (en) | 1994-03-03 | 1995-08-15 | Scimed Lifesystems Inc. | Temporary stent |
US5445594A (en) | 1994-04-05 | 1995-08-29 | Elist; James J. | Implant for expanding penile girth and length |
US5882335A (en) | 1994-09-12 | 1999-03-16 | Cordis Corporation | Retrievable drug delivery stent |
US5902266A (en) | 1994-09-12 | 1999-05-11 | Cordis Corporation | Method for delivering a liquid solution to the interior wall surface of a vessel |
US5545135A (en) | 1994-10-31 | 1996-08-13 | Boston Scientific Corporation | Perfusion balloon stent |
US5669931A (en) | 1995-03-30 | 1997-09-23 | Target Therapeutics, Inc. | Liquid coils with secondary shape |
US5676685A (en) | 1995-06-22 | 1997-10-14 | Razavi; Ali | Temporary stent |
US5697968A (en) | 1995-08-10 | 1997-12-16 | Aeroquip Corporation | Check valve for intraluminal graft |
US6579305B1 (en) * | 1995-12-07 | 2003-06-17 | Medtronic Ave, Inc. | Method and apparatus for delivery deployment and retrieval of a stent comprising shape-memory material |
US6053900A (en) | 1996-02-16 | 2000-04-25 | Brown; Joe E. | Apparatus and method for delivering diagnostic and therapeutic agents intravascularly |
US6050986A (en) | 1997-12-01 | 2000-04-18 | Scimed Life Systems, Inc. | Catheter system for the delivery of a low volume liquid bolus |
US6149677A (en) * | 1998-03-31 | 2000-11-21 | Innercool Therapies, Inc. | Circulating fluid hypothermia method |
US6063101A (en) | 1998-11-20 | 2000-05-16 | Precision Vascular Systems, Inc. | Stent apparatus and method |
US6258118B1 (en) * | 1998-11-25 | 2001-07-10 | Israel Aircraft Industries Ltd. | Removable support device |
US6348067B1 (en) | 1998-11-25 | 2002-02-19 | Israel Aircraft Industries Ltd. | Method and system with shape memory heating apparatus for temporarily supporting a tubular organ |
US6413273B1 (en) | 1998-11-25 | 2002-07-02 | Israel Aircraft Industries Ltd. | Method and system for temporarily supporting a tubular organ |
US20020161427A1 (en) * | 2001-04-27 | 2002-10-31 | Dmitry Rabkin | Methods for delivering, repositioning and/or retrieving self-expanding stents |
Cited By (290)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050187612A1 (en) * | 1998-09-30 | 2005-08-25 | Bard Peripheral Vascular, Inc. | Method of recapturing a stent |
US10278805B2 (en) | 2000-08-18 | 2019-05-07 | Atritech, Inc. | Expandable implant devices for filtering blood flow from atrial appendages |
US7931684B2 (en) * | 2000-10-05 | 2011-04-26 | Edwards Lifesciences Corporation | Minimally-invasive annuloplasty repair segment delivery system |
US20050171601A1 (en) * | 2000-10-05 | 2005-08-04 | Cosgrove Delos M. | Minimally-invasive annuloplasty repair segment delivery system |
US7258696B2 (en) * | 2001-04-27 | 2007-08-21 | Intek Technology L.L.C. | Apparatus for delivering, repositioning and/or retrieving self-expanding stents |
US20040210298A1 (en) * | 2001-04-27 | 2004-10-21 | Intek Technology, L.L.C. | Methods for delivering, repositioning and/or retrieving self-expanding stents |
US20040147939A1 (en) * | 2001-04-27 | 2004-07-29 | Intek Technology, L.L.C. | Apparatus for delivering, repositioning and/or retrieving self-expanding stents |
US7828843B2 (en) | 2001-05-14 | 2010-11-09 | Cardiac Dimensions, Inc. | Mitral valve therapy device, system and method |
US20050027353A1 (en) * | 2001-05-14 | 2005-02-03 | Alferness Clifton A. | Mitral valve therapy device, system and method |
US20050027351A1 (en) * | 2001-05-14 | 2005-02-03 | Cardiac Dimensions, Inc. A Washington Corporation | Mitral valve regurgitation treatment device and method |
US20100100175A1 (en) * | 2001-11-01 | 2010-04-22 | David Reuter | Adjustable Height Focal Tissue Deflector |
US20050021121A1 (en) * | 2001-11-01 | 2005-01-27 | Cardiac Dimensions, Inc., A Delaware Corporation | Adjustable height focal tissue deflector |
US8439971B2 (en) | 2001-11-01 | 2013-05-14 | Cardiac Dimensions, Inc. | Adjustable height focal tissue deflector |
US20070055293A1 (en) * | 2001-12-05 | 2007-03-08 | Alferness Clifton A | Device and method for modifying the shape of a body organ |
US7674287B2 (en) | 2001-12-05 | 2010-03-09 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
US20050149182A1 (en) * | 2001-12-05 | 2005-07-07 | Alferness Clifton A. | Anchor and pull mitral valve device and method |
US7857846B2 (en) | 2001-12-05 | 2010-12-28 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
US8172898B2 (en) | 2001-12-05 | 2012-05-08 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
US20050272969A1 (en) * | 2001-12-05 | 2005-12-08 | Alferness Clifton A | Device and method for modifying the shape of a body organ |
US20060142854A1 (en) * | 2001-12-05 | 2006-06-29 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
US20040193260A1 (en) * | 2001-12-05 | 2004-09-30 | Alferness Clifton A. | Anchor and pull mitral valve device and method |
US10206778B2 (en) | 2002-01-30 | 2019-02-19 | Cardiac Dimensions Pty. Ltd. | Tissue shaping device |
US20080140191A1 (en) * | 2002-01-30 | 2008-06-12 | Cardiac Dimensions, Inc. | Fixed Anchor and Pull Mitral Valve Device and Method |
US8974525B2 (en) | 2002-01-30 | 2015-03-10 | Cardiac Dimensions Pty. Ltd. | Tissue shaping device |
US9320600B2 (en) | 2002-01-30 | 2016-04-26 | Cardiac Dimensions Pty. Ltd. | Tissue shaping device |
US9408695B2 (en) | 2002-01-30 | 2016-08-09 | Cardiac Dimensions Pty. Ltd. | Fixed anchor and pull mitral valve device and method |
US9597186B2 (en) | 2002-01-30 | 2017-03-21 | Cardiac Dimensions Pty. Ltd. | Tissue shaping device |
US20070066879A1 (en) * | 2002-01-30 | 2007-03-22 | Mathis Mark L | Body lumen shaping device with cardiac leads |
US9827099B2 (en) | 2002-01-30 | 2017-11-28 | Cardiac Dimensions Pty. Ltd. | Tissue shaping device |
US9827098B2 (en) | 2002-01-30 | 2017-11-28 | Cardiac Dimensions Pty. Ltd. | Fixed anchor and pull mitral valve device and method |
US10327900B2 (en) | 2002-01-30 | 2019-06-25 | Cardiac Dimensions Pty. Ltd. | Tissue shaping device |
US9827100B2 (en) | 2002-01-30 | 2017-11-28 | Cardiac Dimensions Pty. Ltd. | Tissue shaping device |
US20050216077A1 (en) * | 2002-01-30 | 2005-09-29 | Mathis Mark L | Fixed length anchor and pull mitral valve device and method |
US20110035000A1 (en) * | 2002-01-30 | 2011-02-10 | Cardiac Dimensions, Inc. | Tissue Shaping Device |
US7828842B2 (en) | 2002-01-30 | 2010-11-09 | Cardiac Dimensions, Inc. | Tissue shaping device |
US9956076B2 (en) | 2002-01-30 | 2018-05-01 | Cardiac Dimensions Pty. Ltd. | Tissue shaping device |
US10052205B2 (en) | 2002-01-30 | 2018-08-21 | Cardiac Dimensions Pty. Ltd. | Fixed anchor and pull mitral valve device and method |
US7828841B2 (en) | 2002-05-08 | 2010-11-09 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
US20080097594A1 (en) * | 2002-05-08 | 2008-04-24 | Cardiac Dimensions, Inc. | Device and Method for Modifying the Shape of a Body Organ |
US20050187619A1 (en) * | 2002-05-08 | 2005-08-25 | Mathis Mark L. | Body lumen device anchor, device and assembly |
US20060173536A1 (en) * | 2002-05-08 | 2006-08-03 | Mathis Mark L | Body lumen device anchor, device and assembly |
US10456257B2 (en) | 2002-05-08 | 2019-10-29 | Cardiac Dimensions Pty. Ltd. | Tissue shaping device |
US9474608B2 (en) | 2002-05-08 | 2016-10-25 | Cardiac Dimensions Pty. Ltd. | Body lumen device anchor, device and assembly |
US10456258B2 (en) | 2002-05-08 | 2019-10-29 | Cardiac Dimensions Pty. Ltd. | Tissue shaping device |
US8062358B2 (en) | 2002-05-08 | 2011-11-22 | Cardiac Dimensions, Inc. | Body lumen device anchor, device and assembly |
US8075608B2 (en) | 2002-12-05 | 2011-12-13 | Cardiac Dimensions, Inc. | Medical device delivery system |
US8182529B2 (en) | 2002-12-05 | 2012-05-22 | Cardiac Dimensions, Inc. | Percutaneous mitral valve annuloplasty device delivery method |
US20050096666A1 (en) * | 2002-12-05 | 2005-05-05 | Gordon Lucas S. | Percutaneous mitral valve annuloplasty delivery system |
US20110066234A1 (en) * | 2002-12-05 | 2011-03-17 | Gordon Lucas S | Percutaneous Mitral Valve Annuloplasty Delivery System |
US20080109059A1 (en) * | 2002-12-05 | 2008-05-08 | Cardiac Dimensions, Inc. | Medical Device Delivery System |
US20050119673A1 (en) * | 2002-12-05 | 2005-06-02 | Gordon Lucas S. | Percutaneous mitral valve annuloplasty device delivery method |
US7837729B2 (en) | 2002-12-05 | 2010-11-23 | Cardiac Dimensions, Inc. | Percutaneous mitral valve annuloplasty delivery system |
US7758639B2 (en) | 2003-02-03 | 2010-07-20 | Cardiac Dimensions, Inc. | Mitral valve device using conditioned shape memory alloy |
US20100280602A1 (en) * | 2003-02-03 | 2010-11-04 | Cardiac Dimensions, Inc. | Mitral Valve Device Using Conditioned Shape Memory Alloy |
US20070135912A1 (en) * | 2003-02-03 | 2007-06-14 | Mathis Mark L | Mitral valve device using conditioned shape memory alloy |
US20040193246A1 (en) * | 2003-03-25 | 2004-09-30 | Microvention, Inc. | Methods and apparatus for treating aneurysms and other vascular defects |
US20080015679A1 (en) * | 2003-05-02 | 2008-01-17 | Mathis Mark L | Device and Method for Modifying the Shape of a Body Organ |
US20080015407A1 (en) * | 2003-05-02 | 2008-01-17 | Mathis Mark L | Device and Method for Modifying the Shape of a Body Organ |
US11452603B2 (en) | 2003-05-02 | 2022-09-27 | Cardiac Dimensions Pty. Ltd. | Device and method for modifying the shape of a body organ |
US20080015680A1 (en) * | 2003-05-02 | 2008-01-17 | Mathis Mark L | Device and Method for Modifying the Shape of a Body Organ |
US11311380B2 (en) | 2003-05-02 | 2022-04-26 | Cardiac Dimensions Pty. Ltd. | Device and method for modifying the shape of a body organ |
US7887582B2 (en) | 2003-06-05 | 2011-02-15 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
US20050010240A1 (en) * | 2003-06-05 | 2005-01-13 | Cardiac Dimensions Inc., A Washington Corporation | Device and method for modifying the shape of a body organ |
US20060211984A1 (en) * | 2003-09-23 | 2006-09-21 | C. R. Bard, Inc. | Implant with shape memory |
US20050137451A1 (en) * | 2003-12-19 | 2005-06-23 | Cardiac Dimensions, Inc. A Washington Corporation | Tissue shaping device with integral connector and crimp |
US9526616B2 (en) * | 2003-12-19 | 2016-12-27 | Cardiac Dimensions Pty. Ltd. | Mitral valve annuloplasty device with twisted anchor |
US9956077B2 (en) | 2003-12-19 | 2018-05-01 | Cardiac Dimensions Pty. Ltd. | Mitral valve annuloplasty device with twisted anchor |
US7814635B2 (en) | 2003-12-19 | 2010-10-19 | Cardiac Dimensions, Inc. | Method of making a tissue shaping device |
US7794496B2 (en) | 2003-12-19 | 2010-09-14 | Cardiac Dimensions, Inc. | Tissue shaping device with integral connector and crimp |
US20060191121A1 (en) * | 2003-12-19 | 2006-08-31 | Lucas Gordon | Tissue Shaping Device with Integral Connector and Crimp |
US7837728B2 (en) | 2003-12-19 | 2010-11-23 | Cardiac Dimensions, Inc. | Reduced length tissue shaping device |
US11318016B2 (en) | 2003-12-19 | 2022-05-03 | Cardiac Dimensions Pty. Ltd. | Mitral valve annuloplasty device with twisted anchor |
US20050137449A1 (en) * | 2003-12-19 | 2005-06-23 | Cardiac Dimensions, Inc. | Tissue shaping device with self-expanding anchors |
US11109971B2 (en) | 2003-12-19 | 2021-09-07 | Cardiac Dimensions Pty. Ltd. | Mitral valve annuloplasty device with twisted anchor |
US20060276891A1 (en) * | 2003-12-19 | 2006-12-07 | Gregory Nieminen | Mitral Valve Annuloplasty Device with Twisted Anchor |
US10166102B2 (en) | 2003-12-19 | 2019-01-01 | Cardiac Dimensions Pty. Ltd. | Mitral valve annuloplasty device with twisted anchor |
US20060271174A1 (en) * | 2003-12-19 | 2006-11-30 | Gregory Nieminen | Mitral Valve Annuloplasty Device with Wide Anchor |
US10449048B2 (en) | 2003-12-19 | 2019-10-22 | Cardiac Dimensions Pty. Ltd. | Mitral valve annuloplasty device with twisted anchor |
US8858620B2 (en) | 2003-12-23 | 2014-10-14 | Sadra Medical Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US11696825B2 (en) | 2003-12-23 | 2023-07-11 | Boston Scientific Scimed, Inc. | Replacement valve and anchor |
US7824443B2 (en) | 2003-12-23 | 2010-11-02 | Sadra Medical, Inc. | Medical implant delivery and deployment tool |
US9956075B2 (en) | 2003-12-23 | 2018-05-01 | Boston Scientific Scimed Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US8343213B2 (en) | 2003-12-23 | 2013-01-01 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
US9872768B2 (en) | 2003-12-23 | 2018-01-23 | Boston Scientific Scimed, Inc. | Medical devices and delivery systems for delivering medical devices |
US7959672B2 (en) | 2003-12-23 | 2011-06-14 | Sadra Medical | Replacement valve and anchor |
US9861476B2 (en) | 2003-12-23 | 2018-01-09 | Boston Scientific Scimed Inc. | Leaflet engagement elements and methods for use thereof |
US20050137699A1 (en) * | 2003-12-23 | 2005-06-23 | Sadra Medical, A Delaware Corporation | Methods and apparatus for endovascularly replacing a heart valve |
US8246678B2 (en) | 2003-12-23 | 2012-08-21 | Sadra Medicl, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US20060173524A1 (en) * | 2003-12-23 | 2006-08-03 | Amr Salahieh | Medical Implant Delivery And Deployment Tool |
US7959666B2 (en) | 2003-12-23 | 2011-06-14 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US8579962B2 (en) | 2003-12-23 | 2013-11-12 | Sadra Medical, Inc. | Methods and apparatus for performing valvuloplasty |
US10426608B2 (en) | 2003-12-23 | 2019-10-01 | Boston Scientific Scimed, Inc. | Repositionable heart valve |
US8603160B2 (en) | 2003-12-23 | 2013-12-10 | Sadra Medical, Inc. | Method of using a retrievable heart valve anchor with a sheath |
US7988724B2 (en) | 2003-12-23 | 2011-08-02 | Sadra Medical, Inc. | Systems and methods for delivering a medical implant |
US8623076B2 (en) | 2003-12-23 | 2014-01-07 | Sadra Medical, Inc. | Low profile heart valve and delivery system |
US8623078B2 (en) | 2003-12-23 | 2014-01-07 | Sadra Medical, Inc. | Replacement valve and anchor |
US11285002B2 (en) | 2003-12-23 | 2022-03-29 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US10413412B2 (en) | 2003-12-23 | 2019-09-17 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US10413409B2 (en) | 2003-12-23 | 2019-09-17 | Boston Scientific Scimed, Inc. | Systems and methods for delivering a medical implant |
US8828078B2 (en) | 2003-12-23 | 2014-09-09 | Sadra Medical, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US8840662B2 (en) | 2003-12-23 | 2014-09-23 | Sadra Medical, Inc. | Repositionable heart valve and method |
US8840663B2 (en) | 2003-12-23 | 2014-09-23 | Sadra Medical, Inc. | Repositionable heart valve method |
US10478289B2 (en) | 2003-12-23 | 2019-11-19 | Boston Scientific Scimed, Inc. | Replacement valve and anchor |
US8048153B2 (en) | 2003-12-23 | 2011-11-01 | Sadra Medical, Inc. | Low profile heart valve and delivery system |
US8894703B2 (en) | 2003-12-23 | 2014-11-25 | Sadra Medical, Inc. | Systems and methods for delivering a medical implant |
US11278398B2 (en) | 2003-12-23 | 2022-03-22 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US8052749B2 (en) | 2003-12-23 | 2011-11-08 | Sadra Medical, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US10357359B2 (en) | 2003-12-23 | 2019-07-23 | Boston Scientific Scimed Inc | Methods and apparatus for endovascularly replacing a patient's heart valve |
US9585749B2 (en) | 2003-12-23 | 2017-03-07 | Boston Scientific Scimed, Inc. | Replacement heart valve assembly |
US8252052B2 (en) | 2003-12-23 | 2012-08-28 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8951299B2 (en) | 2003-12-23 | 2015-02-10 | Sadra Medical, Inc. | Medical devices and delivery systems for delivering medical devices |
US10716663B2 (en) | 2003-12-23 | 2020-07-21 | Boston Scientific Scimed, Inc. | Methods and apparatus for performing valvuloplasty |
US8231670B2 (en) | 2003-12-23 | 2012-07-31 | Sadra Medical, Inc. | Repositionable heart valve and method |
US9585750B2 (en) | 2003-12-23 | 2017-03-07 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US10335273B2 (en) | 2003-12-23 | 2019-07-02 | Boston Scientific Scimed Inc. | Leaflet engagement elements and methods for use thereof |
US9005273B2 (en) | 2003-12-23 | 2015-04-14 | Sadra Medical, Inc. | Assessing the location and performance of replacement heart valves |
US9011521B2 (en) | 2003-12-23 | 2015-04-21 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US11185408B2 (en) | 2003-12-23 | 2021-11-30 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US9532872B2 (en) | 2003-12-23 | 2017-01-03 | Boston Scientific Scimed, Inc. | Systems and methods for delivering a medical implant |
US9526609B2 (en) | 2003-12-23 | 2016-12-27 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US10314695B2 (en) | 2003-12-23 | 2019-06-11 | Boston Scientific Scimed Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US10925724B2 (en) | 2003-12-23 | 2021-02-23 | Boston Scientific Scimed, Inc. | Replacement valve and anchor |
US7824442B2 (en) | 2003-12-23 | 2010-11-02 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US9277991B2 (en) | 2003-12-23 | 2016-03-08 | Boston Scientific Scimed, Inc. | Low profile heart valve and delivery system |
US9308085B2 (en) | 2003-12-23 | 2016-04-12 | Boston Scientific Scimed, Inc. | Repositionable heart valve and method |
US8182528B2 (en) | 2003-12-23 | 2012-05-22 | Sadra Medical, Inc. | Locking heart valve anchor |
US9320599B2 (en) | 2003-12-23 | 2016-04-26 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US10258465B2 (en) | 2003-12-23 | 2019-04-16 | Boston Scientific Scimed Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US9358106B2 (en) | 2003-12-23 | 2016-06-07 | Boston Scientific Scimed Inc. | Methods and apparatus for performing valvuloplasty |
US9358110B2 (en) | 2003-12-23 | 2016-06-07 | Boston Scientific Scimed, Inc. | Medical devices and delivery systems for delivering medical devices |
US10772724B2 (en) | 2003-12-23 | 2020-09-15 | Boston Scientific Scimed, Inc. | Medical devices and delivery systems for delivering medical devices |
US10206774B2 (en) | 2003-12-23 | 2019-02-19 | Boston Scientific Scimed Inc. | Low profile heart valve and delivery system |
US9387076B2 (en) | 2003-12-23 | 2016-07-12 | Boston Scientific Scimed Inc. | Medical devices and delivery systems for delivering medical devices |
US9393113B2 (en) | 2003-12-23 | 2016-07-19 | Boston Scientific Scimed Inc. | Retrievable heart valve anchor and method |
US11484405B2 (en) | 2004-06-16 | 2022-11-01 | Boston Scientific Scimed, Inc. | Everting heart valve |
US8668733B2 (en) | 2004-06-16 | 2014-03-11 | Sadra Medical, Inc. | Everting heart valve |
US9744035B2 (en) | 2004-06-16 | 2017-08-29 | Boston Scientific Scimed, Inc. | Everting heart valve |
US8992608B2 (en) | 2004-06-16 | 2015-03-31 | Sadra Medical, Inc. | Everting heart valve |
US8328868B2 (en) | 2004-11-05 | 2012-12-11 | Sadra Medical, Inc. | Medical devices and delivery systems for delivering medical devices |
US8617236B2 (en) | 2004-11-05 | 2013-12-31 | Sadra Medical, Inc. | Medical devices and delivery systems for delivering medical devices |
US10531952B2 (en) | 2004-11-05 | 2020-01-14 | Boston Scientific Scimed, Inc. | Medical devices and delivery systems for delivering medical devices |
US11033257B2 (en) | 2005-01-20 | 2021-06-15 | Cardiac Dimensions Pty. Ltd. | Tissue shaping device |
US11517431B2 (en) | 2005-01-20 | 2022-12-06 | Jenavalve Technology, Inc. | Catheter system for implantation of prosthetic heart valves |
US12016538B2 (en) | 2005-01-20 | 2024-06-25 | Cardiac Dimensions Pty. Ltd. | Tissue shaping device |
US9415225B2 (en) | 2005-04-25 | 2016-08-16 | Cardiac Pacemakers, Inc. | Method and apparatus for pacing during revascularization |
US9649495B2 (en) | 2005-04-25 | 2017-05-16 | Cardiac Pacemakers, Inc. | Method and apparatus for pacing during revascularization |
US10549101B2 (en) | 2005-04-25 | 2020-02-04 | Cardiac Pacemakers, Inc. | Method and apparatus for pacing during revascularization |
US8136659B2 (en) | 2005-09-13 | 2012-03-20 | Sadra Medical, Inc. | Two-part package for medical implant |
US9393094B2 (en) | 2005-09-13 | 2016-07-19 | Boston Scientific Scimed, Inc. | Two-part package for medical implant |
US10370150B2 (en) | 2005-09-13 | 2019-08-06 | Boston Scientific Scimed Inc. | Two-part package for medical implant |
US20090222042A1 (en) * | 2005-10-22 | 2009-09-03 | Paul Firkins | Implant Kit For Supporting A Spinal Column |
US20090048632A1 (en) * | 2005-10-22 | 2009-02-19 | Paul Firkins | Spinal Support Rod Kit |
US8414614B2 (en) | 2005-10-22 | 2013-04-09 | Depuy International Ltd | Implant kit for supporting a spinal column |
US8287584B2 (en) | 2005-11-14 | 2012-10-16 | Sadra Medical, Inc. | Medical implant deployment tool |
US10299922B2 (en) | 2005-12-22 | 2019-05-28 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
US10314701B2 (en) | 2005-12-22 | 2019-06-11 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
US8425563B2 (en) | 2006-01-13 | 2013-04-23 | Depuy International Ltd. | Spinal rod support kit |
US20070179501A1 (en) * | 2006-01-13 | 2007-08-02 | Paul Firkins | Spinal Rod Support Kit |
US20070191831A1 (en) * | 2006-01-26 | 2007-08-16 | Depuy Spine, Inc. | System and method for cooling a spinal correction device comprising a shape memory material for corrective spinal surgery |
US8348952B2 (en) * | 2006-01-26 | 2013-01-08 | Depuy International Ltd. | System and method for cooling a spinal correction device comprising a shape memory material for corrective spinal surgery |
US20070239270A1 (en) * | 2006-04-11 | 2007-10-11 | Mathis Mark L | Mitral Valve Annuloplasty Device with Vena Cava Anchor |
US11285005B2 (en) | 2006-07-17 | 2022-03-29 | Cardiac Dimensions Pty. Ltd. | Mitral valve annuloplasty device with twisted anchor |
US11357624B2 (en) | 2007-04-13 | 2022-06-14 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US9023094B2 (en) | 2007-06-25 | 2015-05-05 | Microvention, Inc. | Self-expanding prosthesis |
US8945172B2 (en) | 2007-10-17 | 2015-02-03 | Covidien Lp | Devices for restoring blood flow and clot removal during acute ischemic stroke |
US10016211B2 (en) | 2007-10-17 | 2018-07-10 | Covidien Lp | Expandable tip assembly for thrombus management |
US9198687B2 (en) | 2007-10-17 | 2015-12-01 | Covidien Lp | Acute stroke revascularization/recanalization systems processes and products thereby |
US8574262B2 (en) | 2007-10-17 | 2013-11-05 | Covidien Lp | Revascularization devices |
US10123803B2 (en) | 2007-10-17 | 2018-11-13 | Covidien Lp | Methods of managing neurovascular obstructions |
US11337714B2 (en) | 2007-10-17 | 2022-05-24 | Covidien Lp | Restoring blood flow and clot removal during acute ischemic stroke |
US8066757B2 (en) | 2007-10-17 | 2011-11-29 | Mindframe, Inc. | Blood flow restoration and thrombus management methods |
US9220522B2 (en) | 2007-10-17 | 2015-12-29 | Covidien Lp | Embolus removal systems with baskets |
US8585713B2 (en) | 2007-10-17 | 2013-11-19 | Covidien Lp | Expandable tip assembly for thrombus management |
US8070791B2 (en) | 2007-10-17 | 2011-12-06 | Mindframe, Inc. | Multiple layer embolus removal |
US11786254B2 (en) | 2007-10-17 | 2023-10-17 | Covidien Lp | Methods of managing neurovascular obstructions |
US8197493B2 (en) | 2007-10-17 | 2012-06-12 | Mindframe, Inc. | Method for providing progressive therapy for thrombus management |
US9320532B2 (en) | 2007-10-17 | 2016-04-26 | Covidien Lp | Expandable tip assembly for thrombus management |
US10413310B2 (en) | 2007-10-17 | 2019-09-17 | Covidien Lp | Restoring blood flow and clot removal during acute ischemic stroke |
US10835257B2 (en) | 2007-10-17 | 2020-11-17 | Covidien Lp | Methods of managing neurovascular obstructions |
US8945143B2 (en) | 2007-10-17 | 2015-02-03 | Covidien Lp | Expandable tip assembly for thrombus management |
US9387098B2 (en) | 2007-10-17 | 2016-07-12 | Covidien Lp | Revascularization devices |
US8430914B2 (en) | 2007-10-24 | 2013-04-30 | Depuy Spine, Inc. | Assembly for orthopaedic surgery |
US8926680B2 (en) | 2007-11-12 | 2015-01-06 | Covidien Lp | Aneurysm neck bridging processes with revascularization systems methods and products thereby |
US8940003B2 (en) | 2008-02-22 | 2015-01-27 | Covidien Lp | Methods and apparatus for flow restoration |
US11529156B2 (en) | 2008-02-22 | 2022-12-20 | Covidien Lp | Methods and apparatus for flow restoration |
US9161766B2 (en) | 2008-02-22 | 2015-10-20 | Covidien Lp | Methods and apparatus for flow restoration |
US8679142B2 (en) | 2008-02-22 | 2014-03-25 | Covidien Lp | Methods and apparatus for flow restoration |
US10456151B2 (en) | 2008-02-22 | 2019-10-29 | Covidien Lp | Methods and apparatus for flow restoration |
US10993805B2 (en) | 2008-02-26 | 2021-05-04 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US11564794B2 (en) | 2008-02-26 | 2023-01-31 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US11154398B2 (en) | 2008-02-26 | 2021-10-26 | JenaValve Technology. Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US8545514B2 (en) | 2008-04-11 | 2013-10-01 | Covidien Lp | Monorail neuro-microcatheter for delivery of medical devices to treat stroke, processes and products thereby |
US8088140B2 (en) | 2008-05-19 | 2012-01-03 | Mindframe, Inc. | Blood flow restorative and embolus removal methods |
US8006594B2 (en) | 2008-08-11 | 2011-08-30 | Cardiac Dimensions, Inc. | Catheter cutting tool |
US20100031793A1 (en) * | 2008-08-11 | 2010-02-11 | Hayner Louis R | Catheter Cutting Tool |
US10722255B2 (en) | 2008-12-23 | 2020-07-28 | Covidien Lp | Systems and methods for removing obstructive matter from body lumens and treating vascular defects |
US20100261662A1 (en) * | 2009-04-09 | 2010-10-14 | Endologix, Inc. | Utilization of mural thrombus for local drug delivery into vascular tissue |
US11589981B2 (en) | 2010-05-25 | 2023-02-28 | Jenavalve Technology, Inc. | Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent |
US10869760B2 (en) | 2010-09-10 | 2020-12-22 | Symetis Sa | Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device |
US10201418B2 (en) | 2010-09-10 | 2019-02-12 | Symetis, SA | Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device |
US8728155B2 (en) | 2011-03-21 | 2014-05-20 | Cephea Valve Technologies, Inc. | Disk-based valve apparatus and method for the treatment of valve dysfunction |
US10456255B2 (en) | 2011-03-21 | 2019-10-29 | Cephea Valve Technologies, Inc. | Disk-based valve apparatus and method for the treatment of valve dysfunction |
US11931252B2 (en) | 2011-03-21 | 2024-03-19 | Cephea Valve Technologies, Inc. | Disk-based valve apparatus and method for the treatment of valve dysfunction |
US11771544B2 (en) | 2011-05-05 | 2023-10-03 | Symetis Sa | Method and apparatus for compressing/loading stent-valves |
US8998976B2 (en) | 2011-07-12 | 2015-04-07 | Boston Scientific Scimed, Inc. | Coupling system for medical devices |
US9555219B2 (en) | 2011-11-10 | 2017-01-31 | Boston Scientific Scimed, Inc. | Direct connect flush system |
US9131926B2 (en) | 2011-11-10 | 2015-09-15 | Boston Scientific Scimed, Inc. | Direct connect flush system |
US10478300B2 (en) | 2011-11-15 | 2019-11-19 | Boston Scientific Scimed, Inc. | Bond between components of a medical device |
US8940014B2 (en) | 2011-11-15 | 2015-01-27 | Boston Scientific Scimed, Inc. | Bond between components of a medical device |
US9642705B2 (en) | 2011-11-15 | 2017-05-09 | Boston Scientific Scimed Inc. | Bond between components of a medical device |
US8951243B2 (en) | 2011-12-03 | 2015-02-10 | Boston Scientific Scimed, Inc. | Medical device handle |
US9370421B2 (en) | 2011-12-03 | 2016-06-21 | Boston Scientific Scimed, Inc. | Medical device handle |
US9510945B2 (en) | 2011-12-20 | 2016-12-06 | Boston Scientific Scimed Inc. | Medical device handle |
US9277993B2 (en) | 2011-12-20 | 2016-03-08 | Boston Scientific Scimed, Inc. | Medical device delivery systems |
US10172708B2 (en) | 2012-01-25 | 2019-01-08 | Boston Scientific Scimed, Inc. | Valve assembly with a bioabsorbable gasket and a replaceable valve implant |
US11382739B2 (en) | 2012-06-19 | 2022-07-12 | Boston Scientific Scimed, Inc. | Replacement heart valve |
US10555809B2 (en) | 2012-06-19 | 2020-02-11 | Boston Scientific Scimed, Inc. | Replacement heart valve |
US8870948B1 (en) | 2013-07-17 | 2014-10-28 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US10624742B2 (en) | 2013-07-17 | 2020-04-21 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US9554899B2 (en) | 2013-07-17 | 2017-01-31 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US11510780B2 (en) | 2013-07-17 | 2022-11-29 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US9561103B2 (en) | 2013-07-17 | 2017-02-07 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US10149761B2 (en) | 2013-07-17 | 2018-12-11 | Cephea Valve Technlologies, Inc. | System and method for cardiac valve repair and replacement |
US10154906B2 (en) | 2013-07-17 | 2018-12-18 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US11185405B2 (en) | 2013-08-30 | 2021-11-30 | Jenavalve Technology, Inc. | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
US11324935B2 (en) | 2014-08-19 | 2022-05-10 | The Regents Of The University Of California | Implants for localized drug delivery and methods of use thereof |
US11918770B2 (en) | 2014-08-19 | 2024-03-05 | The Regents Of The University Of California | Implants for localized drug delivery and methods of use thereof |
US10912933B2 (en) | 2014-08-19 | 2021-02-09 | The Regents Of The University Of California | Implants for localized drug delivery and methods of use thereof |
US9901445B2 (en) | 2014-11-21 | 2018-02-27 | Boston Scientific Scimed, Inc. | Valve locking mechanism |
US10869755B2 (en) | 2014-12-09 | 2020-12-22 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US9439757B2 (en) | 2014-12-09 | 2016-09-13 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US9492273B2 (en) | 2014-12-09 | 2016-11-15 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US10548721B2 (en) | 2014-12-09 | 2020-02-04 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US10433953B2 (en) | 2014-12-09 | 2019-10-08 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US11147665B2 (en) | 2014-12-09 | 2021-10-19 | Cepha Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US10449043B2 (en) | 2015-01-16 | 2019-10-22 | Boston Scientific Scimed, Inc. | Displacement based lock and release mechanism |
US9861477B2 (en) | 2015-01-26 | 2018-01-09 | Boston Scientific Scimed Inc. | Prosthetic heart valve square leaflet-leaflet stitch |
US10201417B2 (en) | 2015-02-03 | 2019-02-12 | Boston Scientific Scimed Inc. | Prosthetic heart valve having tubular seal |
US9788942B2 (en) | 2015-02-03 | 2017-10-17 | Boston Scientific Scimed Inc. | Prosthetic heart valve having tubular seal |
US10285809B2 (en) | 2015-03-06 | 2019-05-14 | Boston Scientific Scimed Inc. | TAVI anchoring assist device |
US10426617B2 (en) | 2015-03-06 | 2019-10-01 | Boston Scientific Scimed, Inc. | Low profile valve locking mechanism and commissure assembly |
US10080652B2 (en) | 2015-03-13 | 2018-09-25 | Boston Scientific Scimed, Inc. | Prosthetic heart valve having an improved tubular seal |
US11337800B2 (en) | 2015-05-01 | 2022-05-24 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
US11786373B2 (en) | 2015-05-14 | 2023-10-17 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
US11617646B2 (en) | 2015-05-14 | 2023-04-04 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10849746B2 (en) | 2015-05-14 | 2020-12-01 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
US10143552B2 (en) | 2015-05-14 | 2018-12-04 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10555808B2 (en) | 2015-05-14 | 2020-02-11 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10470881B2 (en) | 2015-05-14 | 2019-11-12 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US11938027B2 (en) | 2015-06-09 | 2024-03-26 | Edwards Lifesciences, Llc | Asymmetric mitral annuloplasty band |
US10335277B2 (en) | 2015-07-02 | 2019-07-02 | Boston Scientific Scimed Inc. | Adjustable nosecone |
US10195392B2 (en) | 2015-07-02 | 2019-02-05 | Boston Scientific Scimed, Inc. | Clip-on catheter |
US11730595B2 (en) | 2015-07-02 | 2023-08-22 | Boston Scientific Scimed, Inc. | Adjustable nosecone |
US10856973B2 (en) | 2015-08-12 | 2020-12-08 | Boston Scientific Scimed, Inc. | Replacement heart valve implant |
US10136991B2 (en) | 2015-08-12 | 2018-11-27 | Boston Scientific Scimed Inc. | Replacement heart valve implant |
US10179041B2 (en) | 2015-08-12 | 2019-01-15 | Boston Scientific Scimed Icn. | Pinless release mechanism |
US10779940B2 (en) | 2015-09-03 | 2020-09-22 | Boston Scientific Scimed, Inc. | Medical device handle |
US10342660B2 (en) | 2016-02-02 | 2019-07-09 | Boston Scientific Inc. | Tensioned sheathing aids |
US10583005B2 (en) | 2016-05-13 | 2020-03-10 | Boston Scientific Scimed, Inc. | Medical device handle |
US11065138B2 (en) | 2016-05-13 | 2021-07-20 | Jenavalve Technology, Inc. | Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system |
US11382742B2 (en) | 2016-05-13 | 2022-07-12 | Boston Scientific Scimed, Inc. | Medical device handle |
US10245136B2 (en) | 2016-05-13 | 2019-04-02 | Boston Scientific Scimed Inc. | Containment vessel with implant sheathing guide |
US10201416B2 (en) | 2016-05-16 | 2019-02-12 | Boston Scientific Scimed, Inc. | Replacement heart valve implant with invertible leaflets |
US20170325938A1 (en) | 2016-05-16 | 2017-11-16 | Boston Scientific Scimed, Inc. | Replacement heart valve implant with invertible leaflets |
US10709552B2 (en) | 2016-05-16 | 2020-07-14 | Boston Scientific Scimed, Inc. | Replacement heart valve implant with invertible leaflets |
US11331187B2 (en) | 2016-06-17 | 2022-05-17 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
US10828153B2 (en) | 2017-01-23 | 2020-11-10 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US11058535B2 (en) | 2017-01-23 | 2021-07-13 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US11090158B2 (en) | 2017-01-23 | 2021-08-17 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10568737B2 (en) | 2017-01-23 | 2020-02-25 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US11633278B2 (en) | 2017-01-23 | 2023-04-25 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10368990B2 (en) | 2017-01-23 | 2019-08-06 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US11197754B2 (en) | 2017-01-27 | 2021-12-14 | Jenavalve Technology, Inc. | Heart valve mimicry |
US10390953B2 (en) | 2017-03-08 | 2019-08-27 | Cardiac Dimensions Pty. Ltd. | Methods and devices for reducing paravalvular leakage |
US11399939B2 (en) | 2017-03-08 | 2022-08-02 | Cardiac Dimensions Pty. Ltd. | Methods and devices for reducing paravalvular leakage |
US10828154B2 (en) | 2017-06-08 | 2020-11-10 | Boston Scientific Scimed, Inc. | Heart valve implant commissure support structure |
US10898325B2 (en) | 2017-08-01 | 2021-01-26 | Boston Scientific Scimed, Inc. | Medical implant locking mechanism |
US10939996B2 (en) | 2017-08-16 | 2021-03-09 | Boston Scientific Scimed, Inc. | Replacement heart valve commissure assembly |
US11246625B2 (en) | 2018-01-19 | 2022-02-15 | Boston Scientific Scimed, Inc. | Medical device delivery system with feedback loop |
US11191641B2 (en) | 2018-01-19 | 2021-12-07 | Boston Scientific Scimed, Inc. | Inductance mode deployment sensors for transcatheter valve system |
US11147668B2 (en) | 2018-02-07 | 2021-10-19 | Boston Scientific Scimed, Inc. | Medical device delivery system with alignment feature |
US11439732B2 (en) | 2018-02-26 | 2022-09-13 | Boston Scientific Scimed, Inc. | Embedded radiopaque marker in adaptive seal |
US11229517B2 (en) | 2018-05-15 | 2022-01-25 | Boston Scientific Scimed, Inc. | Replacement heart valve commissure assembly |
US11241310B2 (en) | 2018-06-13 | 2022-02-08 | Boston Scientific Scimed, Inc. | Replacement heart valve delivery device |
US11241312B2 (en) | 2018-12-10 | 2022-02-08 | Boston Scientific Scimed, Inc. | Medical device delivery system including a resistance member |
US11439504B2 (en) | 2019-05-10 | 2022-09-13 | Boston Scientific Scimed, Inc. | Replacement heart valve with improved cusp washout and reduced loading |
US11173291B2 (en) | 2020-03-20 | 2021-11-16 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
US11338119B2 (en) | 2020-03-20 | 2022-05-24 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
US11344526B2 (en) | 2020-03-20 | 2022-05-31 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
US11596771B2 (en) | 2020-12-14 | 2023-03-07 | Cardiac Dimensions Pty. Ltd. | Modular pre-loaded medical implants and delivery systems |
Also Published As
Publication number | Publication date |
---|---|
EP1520556B9 (en) | 2008-11-05 |
US20050187612A1 (en) | 2005-08-25 |
US6358276B1 (en) | 2002-03-19 |
EP1520556B1 (en) | 2008-04-09 |
EP1520556A2 (en) | 2005-04-06 |
US20040044394A1 (en) | 2004-03-04 |
JP4295436B2 (en) | 2009-07-15 |
DE69924856D1 (en) | 2005-05-25 |
US6623519B2 (en) | 2003-09-23 |
DE69924856T2 (en) | 2006-03-02 |
US20020087209A1 (en) | 2002-07-04 |
ES2241325T3 (en) | 2005-10-16 |
EP1520556A3 (en) | 2006-08-23 |
EP1117347A1 (en) | 2001-07-25 |
JP4805316B2 (en) | 2011-11-02 |
EP1117347B1 (en) | 2005-04-20 |
DE69938516T2 (en) | 2009-06-25 |
MXPA01003280A (en) | 2002-07-02 |
DE69938516D1 (en) | 2008-05-21 |
CA2345614A1 (en) | 2000-04-06 |
WO2000018327A1 (en) | 2000-04-06 |
JP2008289921A (en) | 2008-12-04 |
JP2002525165A (en) | 2002-08-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6881220B2 (en) | Method of recapturing a stent | |
AU716432B2 (en) | Method and apparatus for delivery, deployment and retrieval of a stent comprising shape-memory material | |
US5993484A (en) | Apparatus and method for dilatation of a body lumen and delivery of a prosthesis therein | |
EP0915678B1 (en) | Surgical implants and delivery systems therefor | |
JP4995088B2 (en) | Thin film medical devices and delivery systems | |
US6413273B1 (en) | Method and system for temporarily supporting a tubular organ | |
US7131986B2 (en) | Catheter having exchangeable balloon | |
EP1996273B1 (en) | A device for delivering medical treatment | |
US6258118B1 (en) | Removable support device | |
US6348067B1 (en) | Method and system with shape memory heating apparatus for temporarily supporting a tubular organ | |
JP2008509724A (en) | Stent with extrusion coating | |
US20070142900A1 (en) | Stent including a portal and methods of use thereof | |
GB2381457A (en) | Dilatation catheter system |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: BARD PERIPHERAL VASCULAR, INC., ARIZONA Free format text: CHANGE OF NAME;ASSIGNOR:IMPRA, INC.;REEL/FRAME:014495/0739 Effective date: 20030505 |
|
CC | Certificate of correction | ||
FPAY | Fee payment |
Year of fee payment: 4 |
|
REMI | Maintenance fee reminder mailed | ||
LAPS | Lapse for failure to pay maintenance fees | ||
STCH | Information on status: patent discontinuation |
Free format text: PATENT EXPIRED DUE TO NONPAYMENT OF MAINTENANCE FEES UNDER 37 CFR 1.362 |
|
FP | Lapsed due to failure to pay maintenance fee |
Effective date: 20130419 |