US3865551A - Laboratory analysis instrument - Google Patents

Laboratory analysis instrument Download PDF

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Publication number
US3865551A
US3865551A US307534A US30753472A US3865551A US 3865551 A US3865551 A US 3865551A US 307534 A US307534 A US 307534A US 30753472 A US30753472 A US 30753472A US 3865551 A US3865551 A US 3865551A
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United States
Prior art keywords
tube
grinding
sample
laboratory analysis
analysis instrument
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US307534A
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English (en)
Inventor
Yoshiko Saiki
Atsushi Saiki
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Individual
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Individual
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Publication date
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Priority to US307534A priority Critical patent/US3865551A/en
Priority to DE2260277A priority patent/DE2260277C3/de
Application granted granted Critical
Publication of US3865551A publication Critical patent/US3865551A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2866—Grinding or homogeneising

Definitions

  • ABSTRACT A kit of implements for laboratory analysis, comprising a tube to contain a sample to be ground, a rod to be appropriately insertible into the tube, and a cap to tightly close the open mouth of the tube, among which the tube is so designed as to be commonly usable either in a grinding operation in combination with the rod or in a sequential physical and/or chemical treatment such as blending, centrifugation, extraction, etc., in combination with the cap, respectively, so that the sequential dual steps may be performed in immediate succession, while eliminating the necessity of transferring the ground sample from a grinding tube to a centrifugal precipitation tube as required in the conventional manner, thereby to prevent loss of the ground sample, which inevitably occurs due to the transfer procedure, thereby to effectively preserve high reliability of the experiment results, and furthermore to substantially save time and trouble required
  • This invention relates to a kit of implements for a certain analysis operation in the laboratory, and particularly to a new and improved implement kit which can be commonly adapted for sequential laboratory operations such as grinding, blending, centrifugation, extraction, etc.. More particularly, the present invention relates to a kit of implements which is adapted to grind a sample in a very effective manner and is specifically designed to integrally cover the abovementioned laboratory operations by making the implement kit versatilely serviceable.
  • kit of implements which comprises a tube and a rod for grinding a sample into small pieces and another tube for further sequential analysis operations in the laboratory.
  • an object of the present invention to provide an instrument which is usable for dual sequential steps in the laboratory analysis procedures, i.e., a grinding procedure and a further sucessive procedure such as blending, centrifugation, extraction, etc. More specifically, an object of this invention is to provide an instrument which is commonly adaptable to the above mentioned two steps, thereby to eliminate the necessity of transferring a ground sample from one instrument to another.
  • Another object of the invention is to provide an instrument which affords, by eliminating the necessity of the transfer procedure, a much higher reliability in the analysis results owing to the prevention of the loss of the sample which is liable to remain within the instrument during the transfer procedure.
  • Still another object of the invention is to provide the above stated instrument in the form of a kit of implements comprising a tube and a rod for grinding performance, which are individually provided with dual, fine and rough grinding surfaces around the circumferential surfaces thereof and in the bottom areas thereof, respectively, for performing effectively a grinding operation.
  • a further object of the invention is to provide an instrument which can be economically made by making the instrument integral or of one-piece structure with dual serviceability instead of the conventional twopiece kit of the implements for a single purpose.
  • a still further object of the invention is to provide an instrument which substantially relieves the laboratory staff of nervous strain due to transfer procedures and also substantially prevents time loss in experimental operations.
  • An additional object of the invention is to provide a kit of implements which may be stored under refrigeration, after being tightly capped, leaving the sample within the tube of the kit free from the trouble of transferring the sample.
  • an instrument which is commonly serviceable for grinding and further successive procedures, consisting essentially of a tube and a rod as a composite kit for a grinding operation, and a tube and a cap as another kit for a further successive procedure such as blending, centrifugation, extraction, etc., by which respective combination of the implements the two steps of grinding and a sequential procedure can readily be performed in immediate succession, making possible such laboratory analysis operations substantially free from loss of the sample during the transfer procedure from one implement to another, and therefore, resulting in high accuracy of the experimental results.
  • the laboratory staff can be substan tially relieved from nervous strain and time loss in a transfer procedure, whereby reliable experimental results can be achieved.
  • FIGS. 1(a) and 1(b) are perspective view showing, in combination, a set of the conventional Potter-Elvehjem instrument and the centrifugal precipitation tube for a centrifugal analysis operation;
  • FIGS. 2(a) and 2(b) are sectional view, partly in schematic form, showing, in combination, one example of the laboratory analysis instrument embodying the invention.
  • a solvent is placed into the Potter tube I to dissolve the ground sample, or at least to keep the sample in wet condition particularly when there is the possibility of the ground sample being scattered into the air during a blending or shaking procedure.
  • the dissolved or wetted sample is then transferred to a centrifugal precipitation tube 5 (hereinafter referred to as a centrifuge tube) or the like for a sequential analysis operation.
  • a centrifugal precipitation tube 5 hereinafter referred to as a centrifuge tube
  • a mortar or sea sand is occasionally applied.
  • the present invention in consideration of the above mentioned defects of the conventional means for laboratory analysis, contemplates advantageous means which completely eliminates the necessity of a transfer procedure of the sample after it is ground and affords an immediately successive operation of the sequential analysis.
  • a glass tube (hereinafter referred to as a Potter tube) is provided with a fine grinding surface 11 almost up to the open mouth thereof, and a fine frosted surface at the inner surface of the open mouth. Surface 11, furthermore, is shifted to a coarse grinding surface toward the bottom area 12, thus providing a coarse surface 13.
  • a stopper 16 has a frosted circumferential surface, and is provided for tightly fitting into and closing the mouth of the Potter tube so as to prevent the dissolved sample from leaking when shaken violently in a centrifuge.
  • the enlarged diametral portion 17 of a rod designed for grinding the sample is provided with a coarse surface in the bottom area 18 thereof and with a fine grinding surface on the outer circumferential surface 19 thereof.
  • the grinding instrument embodying the above mentioned features of construction may be used in the following analytical operations.
  • the sample to be ground is, after being priorly weighed, put into the Potter tube 10 and then ground by means of the rod 15.
  • the coarse grinding surface in the bottom area 18 of the enlarged diametral portion 17 of the grinding rod 15 area 18 contacts with the coarse grinding surface 13 at the bottom area 12 of the Potter tube 10, so that an effective grinding is obtained on the above mentioned sample.
  • a solvent is poured into the Potter tube 10 in order to dissolve the sample. It is recommended that this solvent be poured thereinto in such a manner that the solvent will wash the ground sample away from the rod 15 within the Potter tube 10 so as to prevent loss of the sample which might stick to the rod, in order to precisely preserve the amount of the sample.
  • the Potter tube 10 after being closed with a stopper 16 is then placed onto an appropriate centrifuge for a centrifugal precipitating operation or for other procedures such as blending, shaking, and extraction. After this operation, a gravimetric measurement is conducted on either a precipitate or a supernatant liquid for an analytical experiment to follow.
  • the grinding and further successive procedures can be readily performed without any interruption, thus not only preventing errors from occurring during the transfer procedure of the ground and dissolved sample from a Potter tube to a conventional centrifuge tube or the like, but also effectively shortening the time required for such an analysis operation, and further providing such an economic advantage as enabling the analysis instrument to be made as integral implement instead of the conventional two-piece kit of the implements for independent purposes.
  • the provision of the both fine and coarse grinding surfaces for the grinding rod and Potter tube, respectively results in a remarkably effective grinding operation when compared with the conventional means.
  • the glass tube as referred to in the foregoing disclosure may be made of any other material as, for example a plastic resin, metal or the like having a characteristic which suits its use to accomplish the desired purpose.
  • kit of implements may also be applied to general use such use in the home or commercial kitchen or at the table as a container of foodstuff for blending, shaking, etc. and for refrigeration, the foodstuff being left therewithin.
  • a laboratory analysis instrument comprising, in combination, a tube having a closed bottom and a coarse grinding surface on the inner bottom area thereof, a fine grinding surface at the inner circumferential wall surface extending substantially to the open mouth of said tube, and a finely frosted surface on the inner circumferential wall surface in the upper mouth area of said tube; a grinding rod provided at its lower end with an enlarged diametral portion snugly insertible into said tube for grinding a sample placed into said tube, said enlarged portion having a coarse grinding surface at the bottom area of said portion and having a fine grinding surface at the circumferential wall surface of said portion; and a stopper having a frosted circumferential surface for tightly fitting into and closing the mouth of said tube to prevent thereby leakage of a sample dissolved by a solvent in said tube when shaken in a centrifuge after grinding of said sample.
  • the laboratory analysis instrument as defined in claim 3 including a peripheral lip portion about the top rim of said tube.
US307534A 1972-11-17 1972-11-17 Laboratory analysis instrument Expired - Lifetime US3865551A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US307534A US3865551A (en) 1972-11-17 1972-11-17 Laboratory analysis instrument
DE2260277A DE2260277C3 (de) 1972-11-17 1972-12-08 Laborgerät

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US307534A US3865551A (en) 1972-11-17 1972-11-17 Laboratory analysis instrument
DE2260277A DE2260277C3 (de) 1972-11-17 1972-12-08 Laborgerät

Publications (1)

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US3865551A true US3865551A (en) 1975-02-11

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Application Number Title Priority Date Filing Date
US307534A Expired - Lifetime US3865551A (en) 1972-11-17 1972-11-17 Laboratory analysis instrument

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US (1) US3865551A (de)
DE (1) DE2260277C3 (de)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3941317A (en) * 1973-10-26 1976-03-02 Lnih, Inc. Method and apparatus for tissue disaggregation
US4373674A (en) * 1979-02-14 1983-02-15 Marion Barrera Crushing method and apparatus
FR2523320A1 (fr) * 1982-03-12 1983-09-16 Wright Lab Inc Appareil pour examiner au microscope un echantillon
US5174508A (en) * 1991-08-16 1992-12-29 Source For Automation, Inc. Tablet extraction and analysis system and method
US5223227A (en) * 1989-06-19 1993-06-29 Haemoscope Corporation Disposable pin and cup with reuseable stem and collar for blood coagulation analyzer
US5316732A (en) * 1992-07-01 1994-05-31 Smithkline Diagnostics, Inc. Extraction vial
US5484734A (en) * 1993-03-09 1996-01-16 Torc Seimitsu Industries, Ltd. Reaction vessel for preventing evaporation and a method thereof
US20100083773A1 (en) * 2008-10-04 2010-04-08 Eppendorf Ag Sample carrier
US20100083774A1 (en) * 2008-10-04 2010-04-08 Eppendorf Ag Forensic pipette
US20100167415A1 (en) * 2008-12-30 2010-07-01 Eppendorf Ag Aliquotting device
US20100193524A1 (en) * 2009-02-05 2010-08-05 Eppendorf Ag Preserving container
USD984671S1 (en) 2020-12-09 2023-04-25 Studio 010 Inc. Mortar and pestle

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341356A (en) * 1980-06-16 1982-07-27 Hiott & Bridges, Inc. Pulverizer
CN105728145B (zh) * 2016-04-21 2018-01-26 广西作物遗传改良生物技术重点开放实验室 一种用于组织磨样的磨样器
CN111390196B (zh) * 2020-04-07 2022-06-21 哈尔滨师范大学 一种蛋白银粉末制作反应器

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773468A (en) * 1972-04-03 1973-11-20 R Hubbard Centrifugable extraction and hohogenization vessel

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773468A (en) * 1972-04-03 1973-11-20 R Hubbard Centrifugable extraction and hohogenization vessel

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3941317A (en) * 1973-10-26 1976-03-02 Lnih, Inc. Method and apparatus for tissue disaggregation
US4373674A (en) * 1979-02-14 1983-02-15 Marion Barrera Crushing method and apparatus
FR2523320A1 (fr) * 1982-03-12 1983-09-16 Wright Lab Inc Appareil pour examiner au microscope un echantillon
US5223227A (en) * 1989-06-19 1993-06-29 Haemoscope Corporation Disposable pin and cup with reuseable stem and collar for blood coagulation analyzer
US5174508A (en) * 1991-08-16 1992-12-29 Source For Automation, Inc. Tablet extraction and analysis system and method
US5316732A (en) * 1992-07-01 1994-05-31 Smithkline Diagnostics, Inc. Extraction vial
US5484734A (en) * 1993-03-09 1996-01-16 Torc Seimitsu Industries, Ltd. Reaction vessel for preventing evaporation and a method thereof
US20100083773A1 (en) * 2008-10-04 2010-04-08 Eppendorf Ag Sample carrier
US20100083774A1 (en) * 2008-10-04 2010-04-08 Eppendorf Ag Forensic pipette
US20100167415A1 (en) * 2008-12-30 2010-07-01 Eppendorf Ag Aliquotting device
US20100193524A1 (en) * 2009-02-05 2010-08-05 Eppendorf Ag Preserving container
USD984671S1 (en) 2020-12-09 2023-04-25 Studio 010 Inc. Mortar and pestle

Also Published As

Publication number Publication date
DE2260277B2 (de) 1978-01-19
DE2260277C3 (de) 1978-09-14
DE2260277A1 (de) 1974-06-12

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