US3804899A - 3-alkylamino-2-(3,4-dihydroxyphenyl)propanols and the salts thereof - Google Patents

3-alkylamino-2-(3,4-dihydroxyphenyl)propanols and the salts thereof Download PDF

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Publication number
US3804899A
US3804899A US00183633A US18363371A US3804899A US 3804899 A US3804899 A US 3804899A US 00183633 A US00183633 A US 00183633A US 18363371 A US18363371 A US 18363371A US 3804899 A US3804899 A US 3804899A
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US
United States
Prior art keywords
propanol
dihydroxyphenyl
hydrobromide
carbon atoms
accordance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US00183633A
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English (en)
Inventor
A Ebnother
K Hasspacher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
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Filing date
Publication date
Priority claimed from CH1445970A external-priority patent/CH535739A/de
Priority claimed from CH1446170A external-priority patent/CH534658A/de
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of US3804899A publication Critical patent/US3804899A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
US00183633A 1970-09-30 1971-09-24 3-alkylamino-2-(3,4-dihydroxyphenyl)propanols and the salts thereof Expired - Lifetime US3804899A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1445970A CH535739A (de) 1970-09-30 1970-09-30 Verfahren zur Herstellung neuer Dihydroxyphenylverbindungen
CH1446170A CH534658A (de) 1970-09-30 1970-09-30 Verfahren zur Herstellung neuer Dihydroxyphenylverbindungen

Publications (1)

Publication Number Publication Date
US3804899A true US3804899A (en) 1974-04-16

Family

ID=25714500

Family Applications (1)

Application Number Title Priority Date Filing Date
US00183633A Expired - Lifetime US3804899A (en) 1970-09-30 1971-09-24 3-alkylamino-2-(3,4-dihydroxyphenyl)propanols and the salts thereof

Country Status (10)

Country Link
US (1) US3804899A (de)
AU (1) AU3403671A (de)
BE (1) BE773204A (de)
DD (1) DD99159A5 (de)
DE (1) DE2148551A1 (de)
ES (1) ES395494A1 (de)
FR (1) FR2108100B1 (de)
GB (1) GB1359871A (de)
HU (1) HU162651B (de)
NL (1) NL7112938A (de)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888829A (en) * 1971-06-25 1975-06-10 Sandoz Ag N,n'-bis(3-hydroxy-2-(3,4-dihydroxy-phenyl)-1-propyl)-aliphatic-diamines
US3952021A (en) * 1973-04-28 1976-04-20 Tanabe Seiyaku Co., Ltd. α-(3,4-Dimethoxyphenethylaminomethyl)-3,4 or 3,5-dihydroxybenzylalcohols and salts thereof
US4058642A (en) * 1973-10-11 1977-11-15 Boehringer Ingelheim Gmbh 2-Amino-3-(3'-hydroxy-phenyl)-propanols and salts thereof
US4252824A (en) * 1975-11-12 1981-02-24 Valeas S.R.L., Industria Chimica E Farmaceutica Amino-ethanol derivatives
US4309350A (en) * 1975-11-26 1982-01-05 Commonwealth Scientific And Industrial Research Organization Process of making phenylacrylic esters
US4396517A (en) * 1981-08-10 1983-08-02 Mobil Oil Corporation Phenolic-containing mannich bases and lubricants containing same
US4536601A (en) * 1982-09-28 1985-08-20 Dainippon Pharmaceutical Co., Ltd. Optically active N-substituted phenylalaninols and use thereof
US4788010A (en) * 1985-04-24 1988-11-29 E. R. Squibb & Sons, Inc. Amino substituted benzenepropanols
EP0329464A2 (de) * 1988-02-19 1989-08-23 Gensia, Inc. System zur Verabreichung von einem, eine Übung simulierenden Medikaments im geschlossenen Kreislauf
EP0345591A1 (de) * 1988-06-10 1989-12-13 F. Hoffmann-La Roche Ag Propanolaminderivate
US4994617A (en) * 1986-01-30 1991-02-19 Jouveinal S.A. Aminoalcohols, their preparation process and their applications, particularly in therapeutics
US5770615A (en) * 1996-04-04 1998-06-23 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
US5776983A (en) * 1993-12-21 1998-07-07 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
JP2013177470A (ja) * 2006-07-06 2013-09-09 Array Biopharma Inc Ａｋｔプロテインキナーゼ阻害剤としてのヒドロキシル化およびメトキシル化されたシクロペンタ［ｄ］ピリミジン
US9359340B2 (en) 2006-07-06 2016-06-07 Array Biopharma Inc. Hydroxylated and methoxylated pyrimidyl cyclopentanes as Akt protein kinase inhibitors

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CY1273A (en) 1980-07-09 1985-03-08 Draco Ab 1-(dihydroxyphenyl)-2-amino-ethanol derivatives;preparation,compositions and intermediates
IE903957A1 (en) * 1989-11-06 1991-05-08 Sanofi Sa Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888829A (en) * 1971-06-25 1975-06-10 Sandoz Ag N,n'-bis(3-hydroxy-2-(3,4-dihydroxy-phenyl)-1-propyl)-aliphatic-diamines
US3952021A (en) * 1973-04-28 1976-04-20 Tanabe Seiyaku Co., Ltd. α-(3,4-Dimethoxyphenethylaminomethyl)-3,4 or 3,5-dihydroxybenzylalcohols and salts thereof
US4058642A (en) * 1973-10-11 1977-11-15 Boehringer Ingelheim Gmbh 2-Amino-3-(3'-hydroxy-phenyl)-propanols and salts thereof
US4252824A (en) * 1975-11-12 1981-02-24 Valeas S.R.L., Industria Chimica E Farmaceutica Amino-ethanol derivatives
US4309350A (en) * 1975-11-26 1982-01-05 Commonwealth Scientific And Industrial Research Organization Process of making phenylacrylic esters
US4396517A (en) * 1981-08-10 1983-08-02 Mobil Oil Corporation Phenolic-containing mannich bases and lubricants containing same
US4536601A (en) * 1982-09-28 1985-08-20 Dainippon Pharmaceutical Co., Ltd. Optically active N-substituted phenylalaninols and use thereof
US4788010A (en) * 1985-04-24 1988-11-29 E. R. Squibb & Sons, Inc. Amino substituted benzenepropanols
US4994617A (en) * 1986-01-30 1991-02-19 Jouveinal S.A. Aminoalcohols, their preparation process and their applications, particularly in therapeutics
EP0329464A2 (de) * 1988-02-19 1989-08-23 Gensia, Inc. System zur Verabreichung von einem, eine Übung simulierenden Medikaments im geschlossenen Kreislauf
EP0329464A3 (de) * 1988-02-19 1991-07-17 Gensia, Inc. System zur Verabreichung von einem, eine Übung simulierenden Medikaments im geschlossenen Kreislauf
US5460605A (en) * 1988-02-19 1995-10-24 Gensia, Inc. Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist
EP0345591A1 (de) * 1988-06-10 1989-12-13 F. Hoffmann-La Roche Ag Propanolaminderivate
US5045567A (en) * 1988-06-10 1991-09-03 Hoffmann-La Roche Inc. Propanolamine derivatives having anti-diabetic effects
US5776983A (en) * 1993-12-21 1998-07-07 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
US5770615A (en) * 1996-04-04 1998-06-23 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
JP2013177470A (ja) * 2006-07-06 2013-09-09 Array Biopharma Inc Ａｋｔプロテインキナーゼ阻害剤としてのヒドロキシル化およびメトキシル化されたシクロペンタ［ｄ］ピリミジン
US9359340B2 (en) 2006-07-06 2016-06-07 Array Biopharma Inc. Hydroxylated and methoxylated pyrimidyl cyclopentanes as Akt protein kinase inhibitors

Also Published As

Publication number Publication date
HU162651B (de) 1973-03-28
GB1359871A (en) 1974-07-10
DD99159A5 (de) 1973-07-20
DE2148551A1 (de) 1972-05-10
AU3403671A (en) 1973-04-05
FR2108100A1 (de) 1972-05-12
FR2108100B1 (de) 1975-04-18
NL7112938A (de) 1972-04-05
BE773204A (fr) 1972-03-28
ES395494A1 (es) 1974-11-01

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