US3659104A - Method of measuring serum thyroxine - Google Patents

Method of measuring serum thyroxine Download PDF

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Publication number
US3659104A
US3659104A US51005A US3659104DA US3659104A US 3659104 A US3659104 A US 3659104A US 51005 A US51005 A US 51005A US 3659104D A US3659104D A US 3659104DA US 3659104 A US3659104 A US 3659104A
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US
United States
Prior art keywords
column
serum
thyroxine
gel
iodine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US51005A
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English (en)
Inventor
Jack Gross
Amirav Gordon
Lloyd Alan Schick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JERUSALEM THE, University of
Original Assignee
JERUSALEM THE, University of
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JERUSALEM THE, University of filed Critical JERUSALEM THE, University of
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Publication of US3659104A publication Critical patent/US3659104A/en
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Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/804—Radioisotope, e.g. radioimmunoassay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/825—Pretreatment for removal of interfering factors from sample
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/826—Additives, e.g. buffers, diluents, preservatives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
US51005A 1970-06-29 1970-06-29 Method of measuring serum thyroxine Expired - Lifetime US3659104A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5100570A 1970-06-29 1970-06-29

Publications (1)

Publication Number Publication Date
US3659104A true US3659104A (en) 1972-04-25

Family

ID=21968790

Family Applications (1)

Application Number Title Priority Date Filing Date
US51005A Expired - Lifetime US3659104A (en) 1970-06-29 1970-06-29 Method of measuring serum thyroxine

Country Status (11)

Country Link
US (1) US3659104A (xx)
JP (1) JPS5331399B1 (xx)
CA (1) CA955159A (xx)
DE (1) DE2132112C3 (xx)
ES (1) ES392664A1 (xx)
FR (1) FR2100008A5 (xx)
GB (1) GB1351836A (xx)
HU (1) HU166424B (xx)
IL (1) IL37046A (xx)
SE (1) SE392346B (xx)
ZA (1) ZA713408B (xx)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3753655A (en) * 1971-11-09 1973-08-21 B Schreiber Process for isolation and separation of thyroid hormones
US3816076A (en) * 1971-06-15 1974-06-11 Merck Patent Gmbh Process for the determination of thyroxine
US3911096A (en) * 1972-06-23 1975-10-07 Professional Staff Ass Of The Radioimmunoassay for measurement of thyroxine (T{HD 4{B ) and triiodothyonine (T{HD 3{B ) in blood serum
US3918909A (en) * 1971-09-21 1975-11-11 Philips Corp Apparatus for performing saturation analyses
US3929410A (en) * 1970-11-09 1975-12-30 Benjamin Schloss Analytical process
US3941564A (en) * 1973-09-13 1976-03-02 Miles Laboratories, Inc. Method for assessing thyroid function
US3947564A (en) * 1973-05-29 1976-03-30 Bio-Rad Laboratories Radioactive determination of serum thyroxine
US3961894A (en) * 1973-04-24 1976-06-08 Yissum Research Development Company Test for determination of triiodothyronine
DE2806860A1 (de) * 1977-03-10 1978-09-14 Lepetit Spa Verfahren zur bestimmung der konzentration der freien fraktion eines hormons in einer biologischen fluessigkeit
US4170454A (en) * 1978-03-30 1979-10-09 Union Carbide Corporation Process for the preparation of a solid-phase radioimmunoassay support and use thereof
US4225576A (en) * 1978-11-20 1980-09-30 Miles Laboratories, Inc. Combined radioimmunoassay for triiodothyronine and thyroxine
US4230797A (en) * 1975-04-28 1980-10-28 Miles Laboratories, Inc. Heterogenous specific binding assay employing a coenzyme as label
US4318980A (en) * 1978-04-10 1982-03-09 Miles Laboratories, Inc. Heterogenous specific binding assay employing a cycling reactant as label
US4492751A (en) * 1978-04-10 1985-01-08 Miles Laboratories, Inc. Heterogenous specific binding assay employing an enzyme substrate as label
USRE32098E (en) * 1972-06-23 1986-03-25 Research And Education Institute, Inc. Radioimmunoassay for measurement of thyroxine (T4) and triiodothyronine (T3) in blood serum
US5217903A (en) * 1990-05-15 1993-06-08 Trustees Of Boston University Measuring connective tissue breakdown products in body fluids
KR20020065698A (ko) * 2001-02-07 2002-08-14 주식회사 바이오라인 방사면역측정법을 이용한 갑상선 호르몬 측정키트

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4301139A (en) * 1979-06-21 1981-11-17 Ames-Yissum Ltd. Multilayer column chromatography specific binding assay method, test device and test kit

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3451777A (en) * 1965-08-20 1969-06-24 Walter Di Giulio Method and apparatus for determining the thyroid hormone content of blood
US3507618A (en) * 1964-11-27 1970-04-21 Squibb & Sons Inc Apparatus and method for determining thyroid function

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507618A (en) * 1964-11-27 1970-04-21 Squibb & Sons Inc Apparatus and method for determining thyroid function
US3451777A (en) * 1965-08-20 1969-06-24 Walter Di Giulio Method and apparatus for determining the thyroid hormone content of blood

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929410A (en) * 1970-11-09 1975-12-30 Benjamin Schloss Analytical process
US3816076A (en) * 1971-06-15 1974-06-11 Merck Patent Gmbh Process for the determination of thyroxine
US3918909A (en) * 1971-09-21 1975-11-11 Philips Corp Apparatus for performing saturation analyses
US3753655A (en) * 1971-11-09 1973-08-21 B Schreiber Process for isolation and separation of thyroid hormones
US3911096A (en) * 1972-06-23 1975-10-07 Professional Staff Ass Of The Radioimmunoassay for measurement of thyroxine (T{HD 4{B ) and triiodothyonine (T{HD 3{B ) in blood serum
USRE32098E (en) * 1972-06-23 1986-03-25 Research And Education Institute, Inc. Radioimmunoassay for measurement of thyroxine (T4) and triiodothyronine (T3) in blood serum
US3961894A (en) * 1973-04-24 1976-06-08 Yissum Research Development Company Test for determination of triiodothyronine
US3947564A (en) * 1973-05-29 1976-03-30 Bio-Rad Laboratories Radioactive determination of serum thyroxine
US3941564A (en) * 1973-09-13 1976-03-02 Miles Laboratories, Inc. Method for assessing thyroid function
US4230797A (en) * 1975-04-28 1980-10-28 Miles Laboratories, Inc. Heterogenous specific binding assay employing a coenzyme as label
DE2806860A1 (de) * 1977-03-10 1978-09-14 Lepetit Spa Verfahren zur bestimmung der konzentration der freien fraktion eines hormons in einer biologischen fluessigkeit
US4170454A (en) * 1978-03-30 1979-10-09 Union Carbide Corporation Process for the preparation of a solid-phase radioimmunoassay support and use thereof
US4318980A (en) * 1978-04-10 1982-03-09 Miles Laboratories, Inc. Heterogenous specific binding assay employing a cycling reactant as label
US4492751A (en) * 1978-04-10 1985-01-08 Miles Laboratories, Inc. Heterogenous specific binding assay employing an enzyme substrate as label
US4225576A (en) * 1978-11-20 1980-09-30 Miles Laboratories, Inc. Combined radioimmunoassay for triiodothyronine and thyroxine
US5217903A (en) * 1990-05-15 1993-06-08 Trustees Of Boston University Measuring connective tissue breakdown products in body fluids
KR20020065698A (ko) * 2001-02-07 2002-08-14 주식회사 바이오라인 방사면역측정법을 이용한 갑상선 호르몬 측정키트

Also Published As

Publication number Publication date
HU166424B (xx) 1975-03-28
FR2100008A5 (xx) 1972-03-17
DE2132112A1 (de) 1972-01-27
DE2132112C3 (de) 1974-09-19
ES392664A1 (es) 1973-08-01
GB1351836A (en) 1974-05-01
CA955159A (en) 1974-09-24
IL37046A (en) 1974-05-16
ZA713408B (en) 1972-01-26
JPS5331399B1 (xx) 1978-09-02
SE392346B (sv) 1977-03-21
DE2132112B2 (de) 1974-02-21

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