US3635446A - Liquids shaking device - Google Patents

Liquids shaking device Download PDF

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Publication number
US3635446A
US3635446A US58250A US3635446DA US3635446A US 3635446 A US3635446 A US 3635446A US 58250 A US58250 A US 58250A US 3635446D A US3635446D A US 3635446DA US 3635446 A US3635446 A US 3635446A
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board
frame
holding plate
electric motor
liquid
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US58250A
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Yoshinori Kurosawa
Takashi Katsurasawa
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20Mixing the contents of independent containers, e.g. test tubes
    • B01F31/27Mixing the contents of independent containers, e.g. test tubes the vibrations being caused by electromagnets

Definitions

  • ABSTRACT Liquid-shaking device comprising an elastic frame, a board ..259/54,2g%/3l1Gl./32) held in the upper portion of the frame a holding plate [58] Fie'ld 73 55 56 propped by supports above the board, an electric motor 259/12 i 5 5 suspended underneath the board and an adjustable eccentric weight at the lower end of the axis of the electric motor. Microvibration by the electric motor and the weight is ef- ⁇ 561 References Clted fected over the holding plate to shake the liquid contained in UNITED STATES PATENTS the vessels provided on the holding plate. 3,220,268 11/1965 Brandt ..259/D1G.
  • This invention relates to a device for shaking liquid in vessels or a container enabling the shaking of a group of samples of liquid, say, blood for blood typing, by mechanical vibration.
  • a device for shaking liquid in vessels or a container enabling the shaking of a group of samples of liquid, say, blood for blood typing, by mechanical vibration.
  • the test tube has so far been used, but lately a microplate, or a plastic plate on which many vessels are provided, instead of a test tube, has come to use.
  • the device of this invention is developed to eliminate the said disadvantage.
  • FIG. 1 is a front view, partially cutaway, of an embodiment of the invention.
  • FIG. 2 is a top view of the above embodiment.
  • FIG. 3 is a side view of the microplates piled up.
  • FIG. 4 is a sectional view of the stand.
  • FIG. 5 is a sectional view of the frame.
  • FIG. 6 is a top view of the frame.
  • FIG. 7 is a front view of the suspended electric motor with a weight.
  • FIG. 8 is a top view of the holding plate.
  • FIG. 9 is a sectional view of combination of the holding plate, supports, round board, frame and stand.
  • the embodiment comprises the rubber ring frame I which is seated on the stand 2 embracing the round board 3 within the upper ring groove 4 of the frame as shown in FIG. 5, the said board 3, two supports 5 seated on the board 3 to sustain the holding plate 6, and the electric motor 7 vertically suspended under the board 3 and equipped with the eccentric weight 8 at the lower end of the rotating axis 9 as shown in FIGS. 7.
  • FIG. 2 there is shown the combination of the holding plate 6, the rubber ring frame 1 with four poles 10 in the middle portion of the frame (partially dotted line) and the vertically suspended electric motor (7) as shown in dotted line.
  • the holding plate 6 is sustained above and fixed to the board 3 through the supports 5 by means of studs 11 as fully shown in FIGS. 8 and 9.
  • it is further equipped with two clips 12 on each side of the holding plate to secure the microplate 13 being inserted.
  • the rubber ring frame I with the above-mentioned groove 4 comprises the upper and lower flange portions 14, 15 and four poles 10 in the middle portion as shown in FIGS. 1,2 (partially dotted line), 5 and 9.
  • the strand 2 shown in FIG. 4 is simply for securing the frame 1 and tits in the lower flange portion 15 of the frame at its upper ring portion as shown in FIG. 9.
  • the Shaking Device of this invention has a structure as above mentioned, the microvibration produced and enforced by the rotating motor 7 and the eccentric weight 8 is trans mitted, without impairing its strength, even through the board 3, the rubber ring frame 1, the supports 5 and the holdin plate 6, to the inserted microplate 3.
  • the sample 0 liquid contained in the vessels 17 of the microplate may be shaken evenly and regularly.
  • the microvibration may be adjusted as desired by controlling the velocity of the motor 7 as well as the distance between the weight 8 and the rotating axis 9.
  • the embodiment of this invention illustrated herein is described mainly for application to shaking blood to effect determination of its hemolysis or coagulation employment of the microplate.
  • the device of this invention is not intended only for such limited application, but it can be widely applicable 30 in cases where any type of liquid is to be shaken employing any other type of vessel or plate.
  • the embodiment of this invention is so flexible that the component parts of this invention such as the plate, vessel, etc., can be modified in accordance with the object of local situation.
  • the rubber frame used herein may possibly be substituted with any soft elastic materials such as plastics, etc., and the pole portion attached to the frame may more easily be replaced with springs; the frame in ring form and the board in round form are both changeable to other forms as required; the supports may be in a projection form being integral with the board; and the stand, which is not always essential as a component part, may be made integral with the frame.
  • a liquid-shaking device comprising, an electric frame having an upper and a lower level, said frame having pole portions which support a board at said upper level of said frame, an electric motor suspended from said board in dependent position with respect thereto, supports separate from or integral with the board supporting a plate above the board in mechanical contact through said supports, said plate being adapted to carry vessels for containing liquids, and an eccen tric weight adjustable radially with respect to the lower part of the axis of said motor, whereby upon activation of said motor vibrations are introduced into the mechanism and transmitted to the vessels in said holding plate.

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  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

Liquid-shaking device comprising an elastic frame, a board held in the upper portion of the frame, a holding plate propped by supports above the board, an electric motor suspended underneath the board and an adjustable eccentric weight at the lower end of the axis of the electric motor. Microvibration by the electric motor and the weight is effected over the holding plate to shake the liquid contained in the vessels provided on the holding plate.

Description

D United States Patent [151 3,635,446 Kurosawa et a1. 5] Jan. 18, 1972 541 LIQUIDS SHAKING DEVICE 3,220,704 11/1965 Phillips ..259/54 [72] Inventors: Yoshinori Kurosawa, No. 4914, Ohaza #:Ejgig" g3 Shiba, Kawaguchi; Takashi Katsurasawa, No 18 5 ch0me, Noboritwcho 3,533,602 10/1970 Heck ..259/54 Koshigaya, both of Japan Przmary Examiner-Robert W. Jenkins [22] Filed: July 27, 1970 Attorney-Thomas B, Graham [21] Appl. No.: 58,250 [57] ABSTRACT Liquid-shaking device comprising an elastic frame, a board ..259/54,2g%/3l1Gl./32) held in the upper portion of the frame a holding plate [58] Fie'ld 73 55 56 propped by supports above the board, an electric motor 259/12 i 5 5 suspended underneath the board and an adjustable eccentric weight at the lower end of the axis of the electric motor. Microvibration by the electric motor and the weight is ef- {561 References Clted fected over the holding plate to shake the liquid contained in UNITED STATES PATENTS the vessels provided on the holding plate. 3,220,268 11/1965 Brandt ..259/D1G. 42 11 Claims, 9 Drawing Figures 17 13 i: 1T1 LL 11 IT) |Iool'1 "1TFI /6\ r 5 mi er l FATENTEU JAN 1 81972 SHEEI 1 BF 3 F/Gj l NVEN TOR. TSURA 8A alums/u KA ATTDRIVY PATENTEU um I 8 I972 3,635,446
sum 2 0F 3 F/G4 W INVENTOR.
PATENTEBMWW 3635MB SHEET 3 BF 3 IN VENTOR.
TAKAsH/ KA'TJURASAWA VasH/N m KunosAwA Arron/v LIQUIDS SHARING DEVICE This invention relates to a device for shaking liquid in vessels or a container enabling the shaking of a group of samples of liquid, say, blood for blood typing, by mechanical vibration. For the purpose of blood typing, including determination of the blood hemolysis or coagulation, the test tube has so far been used, but lately a microplate, or a plastic plate on which many vessels are provided, instead of a test tube, has come to use.
Taking an example of a sample of liquid such as the blood, it may be said that in the method of shaking of a microplate by hand, vibration is effected quite unevenly. By that method, in which vibration is by manual power using two plates to be knocked at each end, the minor amount of liquid in the vessels might flow out of the vessel, thus resulting in having a liquid in a vessel mix with that in the adjacent vessels when vigorously shaken, and there might occur some difference in vibration effect between the liquid in the portion close to the place knocked and the remote portion of each plate.
In consideration of the disadvantage of manual operation, a more advanced method of shaking to effect even vibration has been keenly desired particularly by people engaging in blood typing work. In compliance with such demand, the device of this invention is developed to eliminate the said disadvantage.
For further reference the following description is taken in connection with the accompanying drawings specified below:
FIG. 1 is a front view, partially cutaway, of an embodiment of the invention.
FIG. 2 is a top view of the above embodiment.
FIG. 3 is a side view of the microplates piled up.
FIG. 4 is a sectional view of the stand.
FIG. 5 is a sectional view of the frame.
FIG. 6 is a top view of the frame.
FIG. 7 is a front view of the suspended electric motor with a weight.
FIG. 8 is a top view of the holding plate.
FIG. 9 is a sectional view of combination of the holding plate, supports, round board, frame and stand.
Referring to FIG. 1, the components of this invention are collectively illustrated. The embodiment comprises the rubber ring frame I which is seated on the stand 2 embracing the round board 3 within the upper ring groove 4 of the frame as shown in FIG. 5, the said board 3, two supports 5 seated on the board 3 to sustain the holding plate 6, and the electric motor 7 vertically suspended under the board 3 and equipped with the eccentric weight 8 at the lower end of the rotating axis 9 as shown in FIGS. 7.
Referring to FIG. 2, there is shown the combination of the holding plate 6, the rubber ring frame 1 with four poles 10 in the middle portion of the frame (partially dotted line) and the vertically suspended electric motor (7) as shown in dotted line. The holding plate 6 is sustained above and fixed to the board 3 through the supports 5 by means of studs 11 as fully shown in FIGS. 8 and 9. As apparent from the FIGS. 2, 8 and 9, it is further equipped with two clips 12 on each side of the holding plate to secure the microplate 13 being inserted. The
holding plate may hold several microplates by means of suitable bands as shown in FIG. 3. The rubber ring frame I with the above-mentioned groove 4 comprises the upper and lower flange portions 14, 15 and four poles 10 in the middle portion as shown in FIGS. 1,2 (partially dotted line), 5 and 9.
The motor 7, the axis of which is kept vertical, is suspended under the board 3 by the studs 16 as shown in FIG. I and 7. The eccentric weight 8 provided at the lower end of the rotating axis 9, as shown in FIG. 1 and 7, can be properly adjusted by threading it in and out. The strand 2 shown in FIG. 4 is simply for securing the frame 1 and tits in the lower flange portion 15 of the frame at its upper ring portion as shown in FIG. 9.
Since the Shaking Device of this invention has a structure as above mentioned, the microvibration produced and enforced by the rotating motor 7 and the eccentric weight 8 is trans mitted, without impairing its strength, even through the board 3, the rubber ring frame 1, the supports 5 and the holdin plate 6, to the inserted microplate 3. Thus the sample 0 liquid contained in the vessels 17 of the microplate may be shaken evenly and regularly. The microvibration may be adjusted as desired by controlling the velocity of the motor 7 as well as the distance between the weight 8 and the rotating axis 9.
The embodiment of this invention illustrated herein, is described mainly for application to shaking blood to effect determination of its hemolysis or coagulation employment of the microplate. The device of this invention, however, is not intended only for such limited application, but it can be widely applicable 30 in cases where any type of liquid is to be shaken employing any other type of vessel or plate. In other words, the embodiment of this invention is so flexible that the component parts of this invention such as the plate, vessel, etc., can be modified in accordance with the object of local situation. For example, the rubber frame used herein may possibly be substituted with any soft elastic materials such as plastics, etc., and the pole portion attached to the frame may more easily be replaced with springs; the frame in ring form and the board in round form are both changeable to other forms as required; the supports may be in a projection form being integral with the board; and the stand, which is not always essential as a component part, may be made integral with the frame.
What is claimed is:
l. A liquid-shaking device comprising, an electric frame having an upper and a lower level, said frame having pole portions which support a board at said upper level of said frame, an electric motor suspended from said board in dependent position with respect thereto, supports separate from or integral with the board supporting a plate above the board in mechanical contact through said supports, said plate being adapted to carry vessels for containing liquids, and an eccen tric weight adjustable radially with respect to the lower part of the axis of said motor, whereby upon activation of said motor vibrations are introduced into the mechanism and transmitted to the vessels in said holding plate.

Claims (1)

1. A liquid-shaking device comprising, an electric frame having an upper and a lower level, said frame having pole portions which support a board at said upper level of said frame, an electric motor suspended from said board in dependent position with respect thereto, supports separate from or integral with the board supporting a plate above the board in mechanical contact through said supports, said plate being adapted to carry vessels for containing liquids, and an eccentric weight adjustable radially with respect to the lower part of the axis of said motor, whereby upon activation of said motor vibrations are introduced into the mechanism and transmitted to the vessels in said holding plate.
US58250A 1970-07-27 1970-07-27 Liquids shaking device Expired - Lifetime US3635446A (en)

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Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3779681A (en) * 1971-07-06 1973-12-18 T Kinney Apparatus for embedding electron microscopy tissue
US3813816A (en) * 1972-12-12 1974-06-04 C Funk Polishing apparatus
US3944188A (en) * 1974-05-20 1976-03-16 Buchler Instruments Div. Of Searle Analytic Inc. Concentrating vortex shaker
FR2499894A1 (en) * 1981-02-18 1982-08-20 Gorno Metall I Vibratory abrasive finishing machine tool - uses frame on resilient supports to mount stacked plates with cavities for work in abrasive grit
US4571087A (en) * 1983-03-22 1986-02-18 Board Of Regents, University Of Texas System Array sonicator apparatus for automated sample preparation
FR2638103A1 (en) * 1988-10-24 1990-04-27 Herment Dominique ROTARY AGITATOR WITH DRAWERS
US5203385A (en) * 1992-03-31 1993-04-20 Donald Waber Apparatus and process for automatically reconstituting dry materials, especially pharmaceuticals
DE4214913A1 (en) * 1992-05-05 1993-11-11 Liebisch Geb Laboratory glassware shaker with integral damper system - reducing the tendency for the unit to wander around the bench
US20010030906A1 (en) * 1999-12-23 2001-10-18 Friedman Mitchell A. Electromagnetic vibratory microplate shaker
US6565533B1 (en) 2000-01-21 2003-05-20 Novus International, Inc. Inoculation apparatus and method
US6659637B2 (en) 2000-10-03 2003-12-09 Union Scientific Corporation Vertical electromagnetic shaker for biological and chemical specimens
US20070177457A1 (en) * 2006-02-01 2007-08-02 Berthold Technologies Gmbh & Co Kg Shaker
WO2008096018A1 (en) * 2007-02-07 2008-08-14 Centro De Investigación De Rotación Y Torque Aplicada, S.L. Electromagnetic axial agitator
US8016218B1 (en) 2011-03-16 2011-09-13 Mitchell Friedman Linear specimen shaker
CN103272514A (en) * 2013-06-15 2013-09-04 高玉琴 Shaking type blending machine
US20150309025A1 (en) * 2013-07-17 2015-10-29 Gold Standard Diagnostics Process and machine for automated agglutination assays
CN106645769A (en) * 2017-01-22 2017-05-10 王雪游 Method and device for detecting blood coagulation system function by thrombus elasticity diagram
US10222375B2 (en) 2013-07-17 2019-03-05 Gold Standard Diagnostics Process and machine for automated agglutination assays with image automated evaluation
CN110756098A (en) * 2019-11-04 2020-02-07 孙振男 Mixed medicament bottle

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3220704A (en) * 1964-02-25 1965-11-30 Bristol Myers Co Machine for feeding and agitating
US3220268A (en) * 1960-12-27 1965-11-30 Jr Richard W Brandt Vibration generator
US3286939A (en) * 1963-11-26 1966-11-22 Glidden Co Vibratory ball mill
US3430926A (en) * 1967-09-12 1969-03-04 New Brunswick Scientific Co Counterweight system for shaker apparatus
US3533602A (en) * 1966-05-16 1970-10-13 Adolf L Heck Apparatus for riddling bottled wines

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3220268A (en) * 1960-12-27 1965-11-30 Jr Richard W Brandt Vibration generator
US3286939A (en) * 1963-11-26 1966-11-22 Glidden Co Vibratory ball mill
US3220704A (en) * 1964-02-25 1965-11-30 Bristol Myers Co Machine for feeding and agitating
US3533602A (en) * 1966-05-16 1970-10-13 Adolf L Heck Apparatus for riddling bottled wines
US3430926A (en) * 1967-09-12 1969-03-04 New Brunswick Scientific Co Counterweight system for shaker apparatus

Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3779681A (en) * 1971-07-06 1973-12-18 T Kinney Apparatus for embedding electron microscopy tissue
US3813816A (en) * 1972-12-12 1974-06-04 C Funk Polishing apparatus
US3944188A (en) * 1974-05-20 1976-03-16 Buchler Instruments Div. Of Searle Analytic Inc. Concentrating vortex shaker
FR2499894A1 (en) * 1981-02-18 1982-08-20 Gorno Metall I Vibratory abrasive finishing machine tool - uses frame on resilient supports to mount stacked plates with cavities for work in abrasive grit
US4571087A (en) * 1983-03-22 1986-02-18 Board Of Regents, University Of Texas System Array sonicator apparatus for automated sample preparation
EP0368774A2 (en) * 1988-10-24 1990-05-16 Dominique Herment Rotating agitator with drawers
EP0368774A3 (en) * 1988-10-24 1990-05-23 Dominique Herment Rotating agitator with drawers
FR2638103A1 (en) * 1988-10-24 1990-04-27 Herment Dominique ROTARY AGITATOR WITH DRAWERS
US5203385A (en) * 1992-03-31 1993-04-20 Donald Waber Apparatus and process for automatically reconstituting dry materials, especially pharmaceuticals
US5316053A (en) * 1992-03-31 1994-05-31 Donald Waber Apparatus and process for automatically reconstituting dry materials, especially pharmaceuticals
DE4214913A1 (en) * 1992-05-05 1993-11-11 Liebisch Geb Laboratory glassware shaker with integral damper system - reducing the tendency for the unit to wander around the bench
US20010030906A1 (en) * 1999-12-23 2001-10-18 Friedman Mitchell A. Electromagnetic vibratory microplate shaker
US6508582B2 (en) * 1999-12-23 2003-01-21 Union Scientific Corporation Electromagnetic vibratory microplate shaker
US20030229312A1 (en) * 2000-01-21 2003-12-11 Novus International, Inc. Inoculation apparatus and method
US6565533B1 (en) 2000-01-21 2003-05-20 Novus International, Inc. Inoculation apparatus and method
US6659637B2 (en) 2000-10-03 2003-12-09 Union Scientific Corporation Vertical electromagnetic shaker for biological and chemical specimens
US20070177457A1 (en) * 2006-02-01 2007-08-02 Berthold Technologies Gmbh & Co Kg Shaker
US7338199B2 (en) * 2006-02-01 2008-03-04 Berthold Technologies Gmbh & Co Kg Shaker
CN101668582B (en) * 2007-02-07 2013-08-07 旋转转矩应用研究中心 Electromagnetic axial agitator
US20100039886A1 (en) * 2007-02-07 2010-02-18 Cirta, S.L. Electromagnetic axial agitator
US8142067B2 (en) 2007-02-07 2012-03-27 Cirta, S.L. Electromagnetic axial agitator
WO2008096018A1 (en) * 2007-02-07 2008-08-14 Centro De Investigación De Rotación Y Torque Aplicada, S.L. Electromagnetic axial agitator
US8016218B1 (en) 2011-03-16 2011-09-13 Mitchell Friedman Linear specimen shaker
CN103272514A (en) * 2013-06-15 2013-09-04 高玉琴 Shaking type blending machine
US20150309025A1 (en) * 2013-07-17 2015-10-29 Gold Standard Diagnostics Process and machine for automated agglutination assays
US10222375B2 (en) 2013-07-17 2019-03-05 Gold Standard Diagnostics Process and machine for automated agglutination assays with image automated evaluation
CN106645769A (en) * 2017-01-22 2017-05-10 王雪游 Method and device for detecting blood coagulation system function by thrombus elasticity diagram
CN106645769B (en) * 2017-01-22 2019-09-20 王雪游 A kind of method and device of thrombelastogram detection blood coagulation system function
CN110756098A (en) * 2019-11-04 2020-02-07 孙振男 Mixed medicament bottle
CN110756098B (en) * 2019-11-04 2021-11-02 安徽医学高等专科学校 Mixed medicament bottle

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