US3635218A - Combination bulb-piston syringe - Google Patents

Combination bulb-piston syringe Download PDF

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Publication number
US3635218A
US3635218A US21737A US3635218DA US3635218A US 3635218 A US3635218 A US 3635218A US 21737 A US21737 A US 21737A US 3635218D A US3635218D A US 3635218DA US 3635218 A US3635218 A US 3635218A
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United States
Prior art keywords
piston
bulb
syringe
barrel
shaft
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US21737A
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English (en)
Inventor
Richard E Ericson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EILIOT LAB Inc
EILIOT LABORATORIES Inc
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EILIOT LAB Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A61M3/02—Enemata; Irrigators
    • A61M3/0233—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs
    • A61M3/0254—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs the liquid being pumped
    • A61M3/0262—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs the liquid being pumped manually, e.g. by squeezing a bulb
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A61M3/02—Enemata; Irrigators
    • A61M3/0204—Physical characteristics of the irrigation fluid, e.g. conductivity or turbidity
    • A61M3/0208—Physical characteristics of the irrigation fluid, e.g. conductivity or turbidity before use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A61M3/02—Enemata; Irrigators
    • A61M3/0204—Physical characteristics of the irrigation fluid, e.g. conductivity or turbidity
    • A61M3/0216—Pressure

Definitions

  • ABSTRACT A piston-type irrigating syringe, in which the piston shaft, slidable in the syringe barrel with the resilient piston, is hollow and extends into and communicates with an integral resilient hollow bulb and in which the resilient.
  • piston has a restricted passage providing continuous communication between the hollow shaft and bulb and the barrel and nozzle opening of the syringe, whereby the suction and positive pressures applied to a body cavity are applied gradually at a controlled rate and can be varied over a wide gradient, as compared to standard bulb-type syringes and standard piston-type syringes, whereby such pressures and suctions can be controlled to avoid harmful effects, whereby the necessity of employing more than one kind of syringe, i.e., a bulb-type syringe for mild pressures and suctions and a piston-type syringe for greater pressures an suctions, is avoided, whereby the fluid] reservoir capacity is greatly increased over standard syringes, and whereby greater maximum suctions and pressures can be achieved compared to standard syringes.
  • This invention relates to a combined bulb and piston-type medical irrigating syringe for irrigating body cavities and wounds.
  • the syringe is used to irrigate body cavities such as the urinary bladder, or wounds during surgery, by alternately squeezing and releasing the bulb to expel irrigating fluid out of the syringe and into the cavity or wound and to aspirate such fluid into the syringe and out of the cavity or wound, respectively, in a conventional manner.
  • the word bulb refers to any chamber connected to the hollow syringe stem, usually at the end opposite the syringe nozzle, and having a resilient, flexible and squeezable wall, whereby the volume of the chamber can be changed to provide a pumping action to expel a fluid from, and drain or aspirate a fluid into, the syringe. It includes not only the conventional rounded enlarged flexible and resilient bulb but also a cylindrical flexible and resilient enlargement or an accordion type bellows or even a nonenlarged flexible and resilient extension of the syringe stem.
  • the second type of conventional syringe is the piston or plunger-type syringe. This is used for relatively strong irrigations where greater force is required.
  • This type of syringe comprises a conventional syringe barrel, usually rigid, containing a rubbery piston which is in peripheral sealing, but slidable, contact with the internal barrel wall and which is moved axially within the barrel by a solid piston shaft secured thereto to expel irrigating fluid from the barrel into the body cavity or wound and draw it out of the cavity or wound into the barrel.
  • a serious disadvantage of the bulb-type syringe is that the maximum pressures and suctions which can be developed are often insufficient to cope with obstructions in the body cavity or difficult-to-remove debris, e.g., clots, mucous, calculus, cells, etc., or to cope with required flushing in the case of wound irrigations.
  • difficult-to-remove debris e.g., clots, mucous, calculus, cells, etc.
  • a bulb-type syringe is often employed first and if it is not sufficient, the next step would be to use a piston-type syringe, which necessitates the additional cost, storage, time and handling of two syringes in two operations, thereby adding to the complexity of the procedure, further risk of contamination and to the inconvenience of hospital personnel and patient.
  • the syringe of the present invention permits the use of a wide gradient of controlled, cushioned, gradually applied median maximum pressures and suctions between the mild pressures and suctions of a bulb-type syringe and the greater forceful positive pressures and suctions of the piston-type syringe, whereby the sudden buildup of dangerous, excess pressures and suctions upon sudden dislodgement of an obstruction in the body cavity or for any other reason, is avoided.
  • the pressures and suctions applied to the body cavity can only be built up gradually to a safe maximum, the excess pressures and suctions which might nonnally be developed under such circumstances being absorbed or cushioned. Only that pressure or suction required to dislodge the obstruction is built up gradually, and upon dislodgerment, liquid is ejected into the body cavity vor withdrawn from the body cavity without substantially exceeding such required pressure or suction.
  • the syringe of the invention can be used to provide even stronger irrigation than is possible with the piston-type syringe. In addition, it permits a substantial increase in syringe capacity without increasing the physical size of the syringe.
  • the piston shaft of the piston-type syringe with a bulb-type syringe having a hollow stem with the bulb (preferably the bulb and stem are integral) at one end portion and the resilient piston attached to the other end portion and with a passage, preferably a restricted passage or orifice, through the piston providing continuous communication between the barrel and nozzle of the piston syringe and the interior of the hollow stem and bulb.
  • the bulb and stem function as the piston shaft and also as a bulb-type syringe, as will be more fully described hereinafter.
  • FIG. I is a view in elevation of a syringe embodying the present invention.
  • FIG. 2 is a view in perspective of the syringe in FIG. 1.
  • FIG. 3 is a view in perspective from another direction of the syringe of FIG. 2.
  • FIG. 4 is a section taken along the line 4-4 of FIG. 1.
  • 2 is a syringe embodying the present invention and comprising (a) a hollow cylindrical syringe barrel 4, which is made of arigid transparent plastic, such as polypropylene, which hasa tapered hollow nozzle tip 5 at one end forming a nozzle opening 7 of restricted cross section and the other open end 9 of which is of the same diameter as the internal diameter of the syringe barrel proper, (b) a generally cylindrical, hollow, rubber piston or plunger 6, the periphery of which engages the inner wall of the barrel 4 in a fluidtight manner but which is slidable longitudinally in the barrel to draw fluid into, and expel fluid from, the barrel and (c) a piston or plunger shaft 8, which is secured to the piston 6 for sliding the piston back and forth in the barrel and which is in the form of a hollow bulb-type syringe 8 of flexible and resilient plastic, such as an ethylene-vinyl acetate copolymer, comprising a hollow,
  • the upper end of barrel 4 is provided with a pair of laterally extending lugs 14 to provide finger holds during operation of the syringe.
  • the periphery of the rubber piston 6 has a pair of axially spaced annular sealing ribs 16 and 18, extending laterally from the upper and lower ends thereof, as shown, and compressed into sealing relationship with the inside wall of the barrel 4 to form a pair of axially spaced annular fluidtight seals with an annular space 20 formed by the two sealing ribs 16 and 18, the remainder of the periphery of the piston therebetween and the inner wall of the barrel 4.
  • the rubber piston 6 is removably secured to the end of the stem 10 by means of a radially outwardly extending annular lip 22 at the end of the stem protruding radially from the lower end of a reduced diameter end portion 24 of the stem 10 into an internal, undercut, annular groove 26 in the hollow piston 6, with a portion of the piston proper located between the lip 22 and the ledge 31 formed by the reduced portion 24, as shown in FIG. 4.
  • Piston 6 has a lower tapered end wall 28 having a central reduced passage or orifice 30 therein of circular cross-sectional shape and which, in the embodiment shown, is of the same diameter as the nozzle opening 7 and is axially aligned with such nozzle opening.
  • end wall- 28 commences at the bottom of lower rib l8 and tapers downward and inwardly at 29 to the lower end of the orifice 30, as shown. lntemally, the end wall 28 commences at the lower edge of the internal groove 26 (which is located at a height slightly below the upper rib 16 and substantially above the lower rib 18) and tapers downwardly and inwardly at 33 at a steeper inclination than the external taper 29, whereby the thickness of the end wall 28 diminishes in a radially inward direction.
  • the taper of the lower external surface 29 of end wall 28 of the piston 6 is the same as the taper 35 of the end wall 32 of the syringe barrel so that when the piston is pushed fully into the barrel, the lower surface 29 of end wall 28 of the piston mates in close contact with the end wall 32 of the barrel along their areas.
  • the upper end of the bulb 12 is out-of-round slightly at 34 to form a flattened zone for standing the syringe in an upright manner on a relatively flat surface.
  • the flattened zone 34 has a shallow concavity 36 therein for locating the thumb (with the index finger and the adjacent finger under the lugs 14) to squeeze the bulb vertically during use, to thereby provide a more controlled irrigating action, and also to locate the thumb for moving the piston into-the barrel.
  • the syringe is shipped with an internally tapered plastic protective cap (not shown) frictionally but removably secured over the tip 5.
  • a commercial syringe embodying the invention has the following dimensions: lntemal diameter of barrell 7i? inch, internal length of barrel to the lower end of end wall 32-5 inches, length of tip I )6 inch, diameter of opening 7 and orifice SO-three-sixteenths inch, internal diameter of stem-- 1 inch, height of stem-4% inches, diameter of bulb 2% inches, height of piston-eleven/sixteenths inch, thickness of stem wallone thirty-seconds inch, thickness of bulb wall one thirty-seconds one sixty-fourth inch.
  • the normal diameters of the ribs 16 and 18 are slightly greater than the internal diameter of the barrel in order to achieve lateral sealing compression.
  • the annular juncture 38 of the wall between the bulb 12 and stem 10 is slightly enlarged in thickness as compared to the bulb proper and stem to prevent roll over of the bulb onto the upper end of the stern when the bulb is pushed vertically downwardly by the thumb (with the index finger and the next adjacent finger under lugs 14) for piston-type operation and when it is squeezed downwardly by the thumb (with the same fingers under lugs 14) for bulb-type operation.
  • the thickness of the bulb wall at the upper end 40 near and where it flattens out is slightly less than the thickness of the rest of the bulb wall to permit maximum flexure at this area by squeezing down on the top of the bulb with the thumb with the index finger and next adjacent finger under the lugs 14, as aforesaid.
  • the plastic from which the bulb and stem are made can be any plastic or rubber or other elastomer (preferably transparent or translucent) which possesses the properties of being highly flexible, highly resilient, elastic and rubbery with a good memory so that when the bulb is squeezed to deform it, it will immediately spring back or recoil to its original shape when the squeezing pressure is released. Furthermore, it should be highly stable, inert, nontoxic, impervious, resistant to stress cracking and capable of being sterilized. There are a large number of such plastics and rubbers and combinations thereof which are suitable, such as silicone rubber, natural.
  • styrene-butadiene copolymer rubber low density polyethylene
  • plasticized polyvinyl chloride ethylenevinyl acetate copolymer
  • styrene-butadiene thermoplastic elastomers such as those sold under the trade name Kratons by Shell Chemical Company, etc.
  • the piston may be made of natural or synthetic rubber, including styrene-butadiene, or any of the other plastics from which the stem and bulb are made. However, because it has a substantially greater thickness it is stiffer, although still elastic, flexible and resilient for sealing purposes.
  • the piston may be easily secured on and pulled off the end of the stem merely by snapping the lip 22 into and out of the undercut groove 26.
  • the piston may be integral with the stem, and the bulb may be separable from the stem.
  • the bulb When the bulb is separate from the stem it may be made from the same or a different material.
  • the stem and bulb unit is injection blow molded.
  • the barrel 4 may be made of any rigid or semirigid plastic (preferably transparent or translucent) conventionally used for making syringe barrels, or even glass or metal.
  • the barrel is provided with graduation marks and amounts in conventional manner.
  • the syringe shown in the drawings may be used as a true bulb-type syringe by squeezing and releasing the bulb 12 with the stem 10 at all times pushed fully into the barrel 4 so that tapered end wall 29 is snug against the tapered end wall 32 of the barrel. This serves to expel liquid out of and draw liquid into the interior 42 and 46 of the stem and bulb through the nozzle opening 7 and orifice 30.
  • the syringe shown in the drawings may be used as a true piston-type syringe by reciprocating the piston 6 with the stem 10 and bulb 12 full of liquid at all times, e.g., by the bulb action, so that they act as a solid piston shaft. This is effective to expel liquid out of and draw liquid into the interior 44 of the barrel 4 through nozzle opening 7.
  • the operator in applying the syringe to the patient, finds that the bulb procedure, as described aforesaid, does not provide a vigorous enough action he can utilize the piston type procedure, as aforesaid, without the necessity of securing another syringe. Furthermore, if he, at the beginning, believes that a more vigorous type of irrigation is in order but finds that the action is too vigorous, he can utilize the less vigorous bulb type procedure, as aforesaid, without securing another syringe.
  • the combined bulb and piston arrangement of the invention provides a much greater total liquid capacity without adversely increasing the overall bulk and size of the syringe by filling the barrel 4, the bulb 12 and the hollow stem with the stern fully retracted during the irrigation procedure.
  • the particular maximum median pressure and suction achieved can be controlled by controlling the degree to which the stem 10 and bulb 12 are initially filled with liquid between empty and full.
  • the volume of the dead airspaces 42-46 available for compression or expansion is proportionately reduced as compared to an initially empty stern and bulb to decrease the cushioning or absorbing effect.
  • the maximum obstruction release pressure which is built up is increased over a shorter gradient. The same is true for suction aspiration of the body cavity.
  • the doctor by filling the stem and bulb more or less between empty and full, can control the maximum pressures and suctions achieved and the pressure or suction gradient differential to achieve maximum control and safety.
  • the time-pressure gradient achieved using the syringe as a piston-type syringe with an initially empty or partially full stem and bulb can be varied by varying the size of the orifice 30. By decreasing its size, the rate of bleedoff of overpressure or oversuction is reduced. Thus, by varying orifice size, many versatile results can be achieved. It is preferred that the size of the orifice 30 be about equal to or less than the size of the nozzle opening 7. Of course, if the orifice size continues to be decreased, a point will be reached where the action of the stern and bulb begins to approach that of a solid piston shaft. For example, when an orifice one-half the diameter of the nozzle opening was used, the pressure gradient for a given piston movement was increased substantially.
  • the stem may extend entirely through the piston with the orifice 30 located at the reduced lower end of the stem (in such case it is preferred that the stem does not protrude downwardly substantially below the piston in a way to substantially limit the downward movement of the piston and thereby reduce the strolre of the piston). in either case, such orifice passage 30 may be considered from a functional standpoint as being through the piston. Accordingly, when reference is made herein to such passage through the piston both constructions are included.
  • the present invention is most suitable for medical irrigating syringes, as above described, the same principal can be used to advantage with hypodermic-type syringes.
  • a medical pressure regulating syringe comprising a cylindrical syringe barrel having at its nozzle end a restricting opening, a resilient and flexible piston having at least one external, annular sealing rib slidable in said barrel in a fluidtight manner to draw and expel fluid into and out of said barrel through said opening, a hollow tubular piston shaft connected to said piston for sliding movement with said piston and with respect to said barrel, said piston having a cylindrical sidewall portion embracing a portion of the shaft, the internal wall of said cylindrical sidewall portion having an annular groove therein, said portion of said shaft having a reduced neck and a flange ex tending radially outwardly into said groove, said hollow shaft being connected with a chamber communicating with the in terior of said hollow shaft and having a resilient and flexible wall to change the volume of said chamber, said chamber comprising an enlarged, flexible, resilient, squeezable bulb, said shaft and bulb being integral and of plastic, said piston having a passage therethrough providing continuous and uninterrupted communication between the interior of said hollow shaft and
  • a syringe according to claim 1 said integral shaft and bulb being formed from a resilient, flexible and elastic plastic of the group consisting of polyethylene, polyvinyl chloride, ethylene-vinyl acetate copolymer, natural rubber, synthetic rubber and combinations thereof.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
US21737A 1970-03-23 1970-03-23 Combination bulb-piston syringe Expired - Lifetime US3635218A (en)

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US2173770A 1970-03-23 1970-03-23

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Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093108A (en) * 1974-07-11 1978-06-06 Carl Schleicher & Schull Syringe adapted to overcome a pressure resistance
US4113144A (en) * 1976-04-04 1978-09-12 Wolfgang Hein Syringes adapted to overcome a pressure resistance
EP0111724A2 (en) * 1982-12-20 1984-06-27 Becton Dickinson and Company Variable sealing pressure plunger rod assembly
US4483825A (en) * 1982-07-09 1984-11-20 Fatches Keith R Pipette and filter combination
US4543093A (en) * 1982-12-20 1985-09-24 Becton, Dickinson And Company Variable sealing pressure plunger rod assembly
US4693709A (en) * 1985-04-08 1987-09-15 Sherwood Medical Company Syringe
US5176642A (en) * 1991-03-11 1993-01-05 Mectra Labs, Inc. Vacuum powdered syringe
WO1995000195A1 (en) * 1993-06-18 1995-01-05 Habley Medical Technology Corporation Medication sprayer
US5433191A (en) * 1992-05-15 1995-07-18 Habley Medical Technology Corp. Medication sprayer
US5921972A (en) * 1996-01-11 1999-07-13 Skow; Joseph I. Surgical wicking and fluid removal swab
US6109264A (en) * 1996-01-26 2000-08-29 Lasersurge, Inc. Apparatus for expanding body tissue
US6620132B1 (en) 1996-01-11 2003-09-16 Joseph I. Skow Surgical irrigation device
US20050159713A1 (en) * 2004-01-16 2005-07-21 Mcpherson Robert Portable and self-contained lavage apparatus
US20050203463A1 (en) * 2004-03-11 2005-09-15 Merit Medical Systems, Inc. Integral flushing device
US20070000041A1 (en) * 2003-07-08 2007-01-04 Tomoe Masuda Portable bidet
US20070270736A1 (en) * 2005-11-01 2007-11-22 Rosana Giarrocco-Brettner Bulb Syringe Nasal Protection Device
US20090173808A1 (en) * 2008-01-03 2009-07-09 Hsiu-Chun Chen Airbrush structure
US20090202665A1 (en) * 2008-02-13 2009-08-13 Bekan Rhinologics Inc. Nasal irrigation device
US20110159779A1 (en) * 2009-12-24 2011-06-30 Willy Chen Water shooting toy with high capacity
US20110166523A1 (en) * 2008-02-13 2011-07-07 Javer Amin R Nasal irrigation device
US20130324792A1 (en) * 2012-05-31 2013-12-05 Euphoric Products D & M Inc. Targeted lubricant delivery device
US20140378948A1 (en) * 2013-06-19 2014-12-25 Kashiv Pharma, Llc Medicament applicator
US20150239641A1 (en) * 2012-10-01 2015-08-27 Musashi Engineering, Inc. Plunger for dispenser, dispenser, and method for dispensing liquid material
US10238821B2 (en) 2016-10-11 2019-03-26 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
US11317933B1 (en) 2017-10-05 2022-05-03 Nathedra G. White Nasal cleaning tool
US20220362528A1 (en) * 2021-05-11 2022-11-17 Rodney Williams Scalp Treatment Applicator Assembly
US11596746B2 (en) * 2018-12-18 2023-03-07 Shl Medical Ag Medicament delivery device

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4573998A (en) * 1982-02-05 1986-03-04 Staar Surgical Co. Methods for implantation of deformable intraocular lenses

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US822110A (en) * 1905-10-02 1906-05-29 Anne Augustine Gaillot Syringe for subcutaneous or other injections.
US1643531A (en) * 1926-11-15 1927-09-27 Wolf William Syringe for hypodermic needles or the like
US2532598A (en) * 1947-12-08 1950-12-05 Surgident Ltd Guard device for syringes for use with heat-fluent materials
US2735735A (en) * 1956-02-21 Syringe construction
US2841145A (en) * 1956-05-07 1958-07-01 John A Epps Syringe
US2869543A (en) * 1957-08-23 1959-01-20 Iowa Cooperative Ass Injector
US3291128A (en) * 1964-01-24 1966-12-13 John G O'neil Hypodermic syringe construction with sealable vent means
US3295523A (en) * 1963-10-17 1967-01-03 Biolog Res Inc Disposable syringe with novel rebounding squeeze bulb

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2735735A (en) * 1956-02-21 Syringe construction
US822110A (en) * 1905-10-02 1906-05-29 Anne Augustine Gaillot Syringe for subcutaneous or other injections.
US1643531A (en) * 1926-11-15 1927-09-27 Wolf William Syringe for hypodermic needles or the like
US2532598A (en) * 1947-12-08 1950-12-05 Surgident Ltd Guard device for syringes for use with heat-fluent materials
US2841145A (en) * 1956-05-07 1958-07-01 John A Epps Syringe
US2869543A (en) * 1957-08-23 1959-01-20 Iowa Cooperative Ass Injector
US3295523A (en) * 1963-10-17 1967-01-03 Biolog Res Inc Disposable syringe with novel rebounding squeeze bulb
US3291128A (en) * 1964-01-24 1966-12-13 John G O'neil Hypodermic syringe construction with sealable vent means

Cited By (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093108A (en) * 1974-07-11 1978-06-06 Carl Schleicher & Schull Syringe adapted to overcome a pressure resistance
US4113144A (en) * 1976-04-04 1978-09-12 Wolfgang Hein Syringes adapted to overcome a pressure resistance
US4483825A (en) * 1982-07-09 1984-11-20 Fatches Keith R Pipette and filter combination
US4543093A (en) * 1982-12-20 1985-09-24 Becton, Dickinson And Company Variable sealing pressure plunger rod assembly
EP0111724A3 (en) * 1982-12-20 1984-08-01 Becton, Dickinson And Company Variable sealing pressure plunger rod assembly
US4500310A (en) * 1982-12-20 1985-02-19 Becton, Dickinson And Company Variable sealing pressure plunger rod assembly
EP0111724A2 (en) * 1982-12-20 1984-06-27 Becton Dickinson and Company Variable sealing pressure plunger rod assembly
US4693709A (en) * 1985-04-08 1987-09-15 Sherwood Medical Company Syringe
US5176642A (en) * 1991-03-11 1993-01-05 Mectra Labs, Inc. Vacuum powdered syringe
US5433191A (en) * 1992-05-15 1995-07-18 Habley Medical Technology Corp. Medication sprayer
WO1995000195A1 (en) * 1993-06-18 1995-01-05 Habley Medical Technology Corporation Medication sprayer
US5921972A (en) * 1996-01-11 1999-07-13 Skow; Joseph I. Surgical wicking and fluid removal swab
US6620132B1 (en) 1996-01-11 2003-09-16 Joseph I. Skow Surgical irrigation device
US6109264A (en) * 1996-01-26 2000-08-29 Lasersurge, Inc. Apparatus for expanding body tissue
US7475438B2 (en) * 2003-07-08 2009-01-13 Wbe Co., Ltd. Portable bidet
US20070000041A1 (en) * 2003-07-08 2007-01-04 Tomoe Masuda Portable bidet
US20050159713A1 (en) * 2004-01-16 2005-07-21 Mcpherson Robert Portable and self-contained lavage apparatus
US20050203463A1 (en) * 2004-03-11 2005-09-15 Merit Medical Systems, Inc. Integral flushing device
US7591805B2 (en) * 2004-03-11 2009-09-22 Merit Medical Systems, Inc. Integral flushing device
US20070270736A1 (en) * 2005-11-01 2007-11-22 Rosana Giarrocco-Brettner Bulb Syringe Nasal Protection Device
US20090173808A1 (en) * 2008-01-03 2009-07-09 Hsiu-Chun Chen Airbrush structure
US20090202665A1 (en) * 2008-02-13 2009-08-13 Bekan Rhinologics Inc. Nasal irrigation device
US7862548B2 (en) * 2008-02-13 2011-01-04 Bekan Rhinologics Inc. Nasal irrigation device
US20110166523A1 (en) * 2008-02-13 2011-07-07 Javer Amin R Nasal irrigation device
US20110159779A1 (en) * 2009-12-24 2011-06-30 Willy Chen Water shooting toy with high capacity
US20130324792A1 (en) * 2012-05-31 2013-12-05 Euphoric Products D & M Inc. Targeted lubricant delivery device
US20150239641A1 (en) * 2012-10-01 2015-08-27 Musashi Engineering, Inc. Plunger for dispenser, dispenser, and method for dispensing liquid material
US9796518B2 (en) * 2012-10-01 2017-10-24 Musashi Engineering, Inc. Plunger for dispenser, dispenser, and method for dispensing liquid material
US10501256B2 (en) 2012-10-01 2019-12-10 Musashi Engineering, Inc. Plunger for dispenser, dispenser, and method for dispensing liquid material
US20140378948A1 (en) * 2013-06-19 2014-12-25 Kashiv Pharma, Llc Medicament applicator
US9517328B2 (en) * 2013-06-19 2016-12-13 Kashiv Pharma, Llc Medicament applicator
US9884173B2 (en) 2013-06-19 2018-02-06 Kashiv Pharma, Llc Medicament applicator
US10940300B2 (en) 2013-06-19 2021-03-09 Kashiv Pharma, Llc Medicament applicator
US10238821B2 (en) 2016-10-11 2019-03-26 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
US11317933B1 (en) 2017-10-05 2022-05-03 Nathedra G. White Nasal cleaning tool
US11596746B2 (en) * 2018-12-18 2023-03-07 Shl Medical Ag Medicament delivery device
US20220362528A1 (en) * 2021-05-11 2022-11-17 Rodney Williams Scalp Treatment Applicator Assembly

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GB1289183A (sv) 1972-09-13
CA953173A (en) 1974-08-20

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