US3634123A - Method for making nonthrombogenic surfaces - Google Patents

Method for making nonthrombogenic surfaces Download PDF

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Publication number
US3634123A
US3634123A US738826A US3634123DA US3634123A US 3634123 A US3634123 A US 3634123A US 738826 A US738826 A US 738826A US 3634123D A US3634123D A US 3634123DA US 3634123 A US3634123 A US 3634123A
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US
United States
Prior art keywords
plastic
active agent
treated
heparin
article
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US738826A
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English (en)
Inventor
Jan Christer Eriksson
Hans Ragnar Lagergren
Anders Lennart Johansson
Elsa Gunilla Gillberg
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Aminkemi AB
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Individual
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Publication of US3634123A publication Critical patent/US3634123A/en
Assigned to AMINKEMI AKTIEBOLAG reassignment AMINKEMI AKTIEBOLAG CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). EFFECTIVE JULY 11, 1980. Assignors: I.R.D. BIOMATERIAL AKTIEBOLAG
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31652—Of asbestos
    • Y10T428/31663—As siloxane, silicone or silane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31855—Of addition polymer from unsaturated monomers
    • Y10T428/31935—Ester, halide or nitrile of addition polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31855—Of addition polymer from unsaturated monomers
    • Y10T428/31938—Polymer of monoethylenically unsaturated hydrocarbon

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
US738826A 1964-12-17 1968-06-21 Method for making nonthrombogenic surfaces Expired - Lifetime US3634123A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE15249/64A SE306597B (ja) 1964-12-17 1964-12-17

Publications (1)

Publication Number Publication Date
US3634123A true US3634123A (en) 1972-01-11

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ID=20300376

Family Applications (1)

Application Number Title Priority Date Filing Date
US738826A Expired - Lifetime US3634123A (en) 1964-12-17 1968-06-21 Method for making nonthrombogenic surfaces

Country Status (2)

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US (1) US3634123A (ja)
SE (1) SE306597B (ja)

Cited By (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717502A (en) * 1969-06-13 1973-02-20 Medical & Dental Univ Method for providing anticoagulant surfaces onto articles
US3846353A (en) * 1970-06-08 1974-11-05 Department Of Health Education Nonthrombogenic plastic material and method for making the same
US3865615A (en) * 1973-05-07 1975-02-11 Air Prod & Chem Non-thrombogenic plastics
US3932656A (en) * 1970-09-10 1976-01-13 Alza Corporation Article of manufacture for instant release of anti-aggregation and non-thrombogenic agents to biological media
US4048064A (en) * 1976-04-23 1977-09-13 Clark Iii William T Biocompatible hemoperfusion system
US4116898A (en) * 1977-01-31 1978-09-26 Becton, Dickinson And Company Non-thrombogenic articles
US4118485A (en) * 1975-03-20 1978-10-03 Aminkemi Aktiebolag Non-thrombogenic medical article and a method for its preparation
DE2831360A1 (de) * 1977-07-18 1979-02-08 Aminkemi Ab Verfahren und mittel zur heparinisierung einer geladenen oberflaeche eines medizinischen gegenstandes
US4273873A (en) * 1977-10-25 1981-06-16 Unitika Ltd. Preparation of antithrombogenic polymeric materials
US4302368A (en) * 1978-04-24 1981-11-24 Becton, Dickinson And Company Nonthrombogenic articles and method of preparation
WO1981003277A1 (en) * 1980-05-23 1981-11-26 Riker Laboratories Inc Heparin web and process
US4308232A (en) * 1979-07-09 1981-12-29 Sherwood Medical Industries Inc. Anticoagulant stopper coating
US4349467A (en) * 1977-01-31 1982-09-14 Williams Joel L Nonthrombogenic articles and method of preparation
US4405612A (en) * 1980-05-23 1983-09-20 Riker Laboratories, Inc. Heparin web compositions
US4479799A (en) * 1981-05-21 1984-10-30 Riker Laboratories, Inc. Hypodermic syringe containing microfibers of an amorphous heparin salt
US4530974A (en) * 1981-03-19 1985-07-23 Board Of Regents, The University Of Texas System Nonthrombogenic articles having enhanced albumin affinity
US4613517A (en) * 1983-04-27 1986-09-23 Becton, Dickinson And Company Heparinization of plasma treated surfaces
US4865870A (en) * 1988-07-07 1989-09-12 Becton, Dickinson And Company Method for rendering a substrate surface antithrombogenic
US4871357A (en) * 1986-01-21 1989-10-03 Baxter International Inc. Ionic heparin coating
US4914041A (en) * 1988-02-12 1990-04-03 Beckman Instruments, Inc. Reagent and method for detecting rheumatoid factor
EP0365536A1 (en) * 1987-05-04 1990-05-02 Albert J Banes POLYORGANOSILOXANE COMPOSITION WITH A BIOCOMPATIBLE SURFACE FOR CELL CULTURE APPARATUS.
US5047020A (en) * 1987-09-14 1991-09-10 Baxter International Inc. Ionic heparin coating
US5135516A (en) * 1989-12-15 1992-08-04 Boston Scientific Corporation Lubricious antithrombogenic catheters, guidewires and coatings
US5159050A (en) * 1991-05-09 1992-10-27 Becton, Dickinson And Company Polyurethane and medical article therefrom
US5159051A (en) * 1991-05-09 1992-10-27 Becton, Dickinson And Company Biostable polyurethane
US5322659A (en) * 1990-09-21 1994-06-21 Becton, Dickinson And Company Method for rendering a substrate surface antithrombogenic and/or anti-infective
US5328698A (en) * 1990-08-06 1994-07-12 Becton, Dickinson And Company Method for rendering a substrate surface antithrombogenic and/or anti-infective
US5532311A (en) * 1995-02-01 1996-07-02 Minnesota Mining And Manufacturing Company Process for modifying surfaces
US5583213A (en) * 1995-05-12 1996-12-10 Minnesota Mining And Manufacturing Company Process to activate sulfated polysaccharides
US5922690A (en) * 1996-04-25 1999-07-13 Van Gorp; Cornelius L. Dermatan disulfate, an inhibitor of thrombin generation and activation
US6146771A (en) * 1997-07-01 2000-11-14 Terumo Cardiovascular Systems Corporation Process for modifying surfaces using the reaction product of a water-insoluble polymer and a polyalkylene imine
US6197289B1 (en) 1997-07-01 2001-03-06 Terumo Cardiovascular Systems Corporation Removal of biologically active agents
US6251964B1 (en) 1996-11-20 2001-06-26 Biocompatibles Limited Biocompatible compositions
US6309660B1 (en) 1999-07-28 2001-10-30 Edwards Lifesciences Corp. Universal biocompatible coating platform for medical devices
US6340465B1 (en) 1999-04-12 2002-01-22 Edwards Lifesciences Corp. Lubricious coatings for medical devices
US6409987B1 (en) 1999-04-07 2002-06-25 Intimax Corporation Targeted agents useful for diagnostic and therapeutic applications
US6416549B1 (en) 1999-07-19 2002-07-09 Sulzer Carbomedics Inc. Antithrombogenic annuloplasty ring having a biodegradable insert
DE10106362A1 (de) * 2001-02-12 2002-09-12 Michael Licht Vorrichtung und Verfahren zum Sammeln von wässrigen Flüssigkeitsproben
US6599558B1 (en) 1997-06-03 2003-07-29 Polybiomed Limited Treating metal surfaces to enhance bio-compatibility and/or physical characteristics
US6755824B2 (en) 2002-04-15 2004-06-29 Uab Research Foundation Platelet inhibitor eluting ablation catheter
US20040176556A1 (en) * 1991-07-05 2004-09-09 Biocompatibles Limited Polymeric surface coatings
ES2224898A1 (es) * 2004-10-15 2005-03-01 Universitat Autonoma De Barcelona Procedimiento para la modificacion de superficies de metales, de semiconductores y de carbono, productos modificados superficialmente asi obtenidos y sus aplicaciones.
US20050090891A1 (en) * 1989-12-15 2005-04-28 Sahatjian Ronald A. Stent lining
US8480227B2 (en) 2010-07-30 2013-07-09 Novartis Ag Silicone hydrogel lenses with water-rich surfaces
US9005700B2 (en) 2011-10-12 2015-04-14 Novartis Ag Method for making UV-absorbing ophthalmic lenses
US20150352265A1 (en) * 2013-01-07 2015-12-10 Narayana GARIMELLA Biocompatible coating composition
US9708087B2 (en) 2013-12-17 2017-07-18 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
US10338408B2 (en) 2012-12-17 2019-07-02 Novartis Ag Method for making improved UV-absorbing ophthalmic lenses
US10449740B2 (en) 2015-12-15 2019-10-22 Novartis Ag Method for applying stable coating on silicone hydrogel contact lenses
US10830923B2 (en) 2017-12-13 2020-11-10 Alcon Inc. Method for producing MPS-compatible water gradient contact lenses
US11002884B2 (en) 2014-08-26 2021-05-11 Alcon Inc. Method for applying stable coating on silicone hydrogel contact lenses
US11613719B2 (en) 2018-09-24 2023-03-28 Becton, Dickinson And Company Self-lubricating medical articles

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Gott et al., Heparin Bonding on Colloidal Graphite Surfaces Science, V. 132 Dec. 1963, pp. 1297 1298 *

Cited By (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717502A (en) * 1969-06-13 1973-02-20 Medical & Dental Univ Method for providing anticoagulant surfaces onto articles
US3846353A (en) * 1970-06-08 1974-11-05 Department Of Health Education Nonthrombogenic plastic material and method for making the same
US3932656A (en) * 1970-09-10 1976-01-13 Alza Corporation Article of manufacture for instant release of anti-aggregation and non-thrombogenic agents to biological media
US3865615A (en) * 1973-05-07 1975-02-11 Air Prod & Chem Non-thrombogenic plastics
US4118485A (en) * 1975-03-20 1978-10-03 Aminkemi Aktiebolag Non-thrombogenic medical article and a method for its preparation
US4048064A (en) * 1976-04-23 1977-09-13 Clark Iii William T Biocompatible hemoperfusion system
US4349467A (en) * 1977-01-31 1982-09-14 Williams Joel L Nonthrombogenic articles and method of preparation
US4116898A (en) * 1977-01-31 1978-09-26 Becton, Dickinson And Company Non-thrombogenic articles
DE2831360A1 (de) * 1977-07-18 1979-02-08 Aminkemi Ab Verfahren und mittel zur heparinisierung einer geladenen oberflaeche eines medizinischen gegenstandes
US4265927A (en) * 1977-07-18 1981-05-05 Aminkemi Ab Method of heparinizing a charged surface of a medical article intended for blood contact
US4273873A (en) * 1977-10-25 1981-06-16 Unitika Ltd. Preparation of antithrombogenic polymeric materials
US4302368A (en) * 1978-04-24 1981-11-24 Becton, Dickinson And Company Nonthrombogenic articles and method of preparation
US4308232A (en) * 1979-07-09 1981-12-29 Sherwood Medical Industries Inc. Anticoagulant stopper coating
WO1981003277A1 (en) * 1980-05-23 1981-11-26 Riker Laboratories Inc Heparin web and process
US4405612A (en) * 1980-05-23 1983-09-20 Riker Laboratories, Inc. Heparin web compositions
US4530974A (en) * 1981-03-19 1985-07-23 Board Of Regents, The University Of Texas System Nonthrombogenic articles having enhanced albumin affinity
US4479799A (en) * 1981-05-21 1984-10-30 Riker Laboratories, Inc. Hypodermic syringe containing microfibers of an amorphous heparin salt
US4613517A (en) * 1983-04-27 1986-09-23 Becton, Dickinson And Company Heparinization of plasma treated surfaces
US4871357A (en) * 1986-01-21 1989-10-03 Baxter International Inc. Ionic heparin coating
EP0365536B1 (en) * 1987-05-04 1996-10-23 BANES, Albert J. Biocompatible polyorganosiloxane composition for cell culture apparatus
EP0365536A1 (en) * 1987-05-04 1990-05-02 Albert J Banes POLYORGANOSILOXANE COMPOSITION WITH A BIOCOMPATIBLE SURFACE FOR CELL CULTURE APPARATUS.
US5047020A (en) * 1987-09-14 1991-09-10 Baxter International Inc. Ionic heparin coating
US4914041A (en) * 1988-02-12 1990-04-03 Beckman Instruments, Inc. Reagent and method for detecting rheumatoid factor
US4865870A (en) * 1988-07-07 1989-09-12 Becton, Dickinson And Company Method for rendering a substrate surface antithrombogenic
US5135516A (en) * 1989-12-15 1992-08-04 Boston Scientific Corporation Lubricious antithrombogenic catheters, guidewires and coatings
US7371257B2 (en) 1989-12-15 2008-05-13 Boston Scientific Scimed, Inc. Stent lining
US20050090891A1 (en) * 1989-12-15 2005-04-28 Sahatjian Ronald A. Stent lining
US5328698A (en) * 1990-08-06 1994-07-12 Becton, Dickinson And Company Method for rendering a substrate surface antithrombogenic and/or anti-infective
US5322659A (en) * 1990-09-21 1994-06-21 Becton, Dickinson And Company Method for rendering a substrate surface antithrombogenic and/or anti-infective
US5159051A (en) * 1991-05-09 1992-10-27 Becton, Dickinson And Company Biostable polyurethane
US5159050A (en) * 1991-05-09 1992-10-27 Becton, Dickinson And Company Polyurethane and medical article therefrom
US7160953B2 (en) 1991-07-05 2007-01-09 Biocompatibles Uk Limited Polymeric surface coatings
US20040176556A1 (en) * 1991-07-05 2004-09-09 Biocompatibles Limited Polymeric surface coatings
US5532311A (en) * 1995-02-01 1996-07-02 Minnesota Mining And Manufacturing Company Process for modifying surfaces
US5583213A (en) * 1995-05-12 1996-12-10 Minnesota Mining And Manufacturing Company Process to activate sulfated polysaccharides
US5922690A (en) * 1996-04-25 1999-07-13 Van Gorp; Cornelius L. Dermatan disulfate, an inhibitor of thrombin generation and activation
US6251964B1 (en) 1996-11-20 2001-06-26 Biocompatibles Limited Biocompatible compositions
US6599558B1 (en) 1997-06-03 2003-07-29 Polybiomed Limited Treating metal surfaces to enhance bio-compatibility and/or physical characteristics
US6197289B1 (en) 1997-07-01 2001-03-06 Terumo Cardiovascular Systems Corporation Removal of biologically active agents
US6146771A (en) * 1997-07-01 2000-11-14 Terumo Cardiovascular Systems Corporation Process for modifying surfaces using the reaction product of a water-insoluble polymer and a polyalkylene imine
US6409987B1 (en) 1999-04-07 2002-06-25 Intimax Corporation Targeted agents useful for diagnostic and therapeutic applications
US6340465B1 (en) 1999-04-12 2002-01-22 Edwards Lifesciences Corp. Lubricious coatings for medical devices
US6416549B1 (en) 1999-07-19 2002-07-09 Sulzer Carbomedics Inc. Antithrombogenic annuloplasty ring having a biodegradable insert
US6309660B1 (en) 1999-07-28 2001-10-30 Edwards Lifesciences Corp. Universal biocompatible coating platform for medical devices
DE10106362A1 (de) * 2001-02-12 2002-09-12 Michael Licht Vorrichtung und Verfahren zum Sammeln von wässrigen Flüssigkeitsproben
DE10106362B4 (de) * 2001-02-12 2005-03-17 Licht, Michael, Dipl.-Ing. (FH) Vorrichtung und Verfahren zum Sammeln von wässrigen Flüssigkeitsproben
US6755824B2 (en) 2002-04-15 2004-06-29 Uab Research Foundation Platelet inhibitor eluting ablation catheter
ES2224898A1 (es) * 2004-10-15 2005-03-01 Universitat Autonoma De Barcelona Procedimiento para la modificacion de superficies de metales, de semiconductores y de carbono, productos modificados superficialmente asi obtenidos y sus aplicaciones.
WO2006042892A1 (es) * 2004-10-15 2006-04-27 Universitat Autonoma De Barcelona Procedimiento para la modificación de superficies de metales, de semiconductores y de carbono, productos modificados superficialmente así obtenidos y sus aplicaciones
US9239409B2 (en) 2010-07-30 2016-01-19 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
US9738813B2 (en) 2010-07-30 2017-08-22 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
US8939577B2 (en) 2010-07-30 2015-01-27 Novartis Ag Silicone hydrogel lenses with water-rich surfaces
US8944592B2 (en) 2010-07-30 2015-02-03 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
US10781340B2 (en) 2010-07-30 2020-09-22 Alcon Inc. Silicone hydrogel lenses with water-rich surfaces
US9816009B2 (en) 2010-07-30 2017-11-14 Novartis Ag Silicone hydrogel lenses with water-rich surfaces
US8480227B2 (en) 2010-07-30 2013-07-09 Novartis Ag Silicone hydrogel lenses with water-rich surfaces
US9244200B2 (en) 2010-07-30 2016-01-26 Novartis Ag Silicone hydrogel lenses with water-rich surfaces
US9411171B2 (en) 2010-07-30 2016-08-09 Novartis Ag Silicone hydrogel lenses with water-rich surfaces
US9507173B2 (en) 2010-07-30 2016-11-29 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
US8529057B2 (en) 2010-07-30 2013-09-10 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
US9005700B2 (en) 2011-10-12 2015-04-14 Novartis Ag Method for making UV-absorbing ophthalmic lenses
US10338408B2 (en) 2012-12-17 2019-07-02 Novartis Ag Method for making improved UV-absorbing ophthalmic lenses
US20150352265A1 (en) * 2013-01-07 2015-12-10 Narayana GARIMELLA Biocompatible coating composition
US9708087B2 (en) 2013-12-17 2017-07-18 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
US11002884B2 (en) 2014-08-26 2021-05-11 Alcon Inc. Method for applying stable coating on silicone hydrogel contact lenses
US10449740B2 (en) 2015-12-15 2019-10-22 Novartis Ag Method for applying stable coating on silicone hydrogel contact lenses
US10830923B2 (en) 2017-12-13 2020-11-10 Alcon Inc. Method for producing MPS-compatible water gradient contact lenses
US11029446B2 (en) 2017-12-13 2021-06-08 Alcon Inc. Method for producing MPS-compatible water gradient contact lenses
US11029447B2 (en) 2017-12-13 2021-06-08 Alcon Inc. Method for producing MPS-compatible water gradient contact lenses
US11256003B2 (en) 2017-12-13 2022-02-22 Alcon Inc. Weekly and monthly disposable water gradient contact lenses
US11613719B2 (en) 2018-09-24 2023-03-28 Becton, Dickinson And Company Self-lubricating medical articles

Also Published As

Publication number Publication date
SE306597B (ja) 1968-12-02

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Legal Events

Date Code Title Description
AS Assignment

Owner name: AMINKEMI AKTIEBOLAG

Free format text: CHANGE OF NAME;ASSIGNOR:I.R.D. BIOMATERIAL AKTIEBOLAG;REEL/FRAME:003866/0709

Effective date: 19810505