US3622053A - Aerosol inhaler with flip-up nozzle - Google Patents

Aerosol inhaler with flip-up nozzle Download PDF

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Publication number
US3622053A
US3622053A US883752A US3622053DA US3622053A US 3622053 A US3622053 A US 3622053A US 883752 A US883752 A US 883752A US 3622053D A US3622053D A US 3622053DA US 3622053 A US3622053 A US 3622053A
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US
United States
Prior art keywords
container
hood
dispenser
open
valve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US883752A
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English (en)
Inventor
John V Ryden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
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Filing date
Publication date
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0023—Mouthpieces therefor retractable

Definitions

  • the dispenser comprising a housing having a skirt open at its lower end for receiving the container and a dispensing head, the dispensing head having a valve activator therein including a boss having an opening for engaging and gripping the valve stem on the container for maintaining the container in the dispenser and a nozzle hood pivotally mounted on the dispensing head for receiving a metered amount of medication from the container and mixing such metered amount of medication with the air drawn through such hood by the patient, the nozzle hood including means, when said nozzle hood is closed, for abutting said container and for preventing said container from being moved axially of said dispenser for opening said valve PATENTEDN 23 I l 3.622 O53 (iLllligli li INVENTOR.
  • This invention relates to a dispensing device for aerosol products, that is, for products that are confined under pressure within a container and dispensed therefrom in the fonn of 5
  • The-administration of medicinal agents by inhalation has many advantages as compared with alternate methods. Inhalationis quick and easy and may be accomplished by the patient without assistance or difficulty. In addition, response to this type of administration is prompt because of the direct application of the medicinal agent to the affected area. Prompt response and administration by the patient are of particular importance where the patient is subject to attacks, such as, for example, asthma attacks, where such attacks are unpredictable and may occur at any time.
  • One means found to be particularly effective in the administration of medical agents by inhalation is by packaging the medicament, as for example antibiotics, anesthetics, antiseptics, antihistamines, and the like, and combinations thereof, in a container with a propellant, such as Freon.
  • a container with a propellant such as Freon.
  • Such container is provided with a valve which, when depressed, discharges the medicament in a mist or spray.
  • Such containers are relatively small and can be carried in a pocketbook, purse or pocket so that, when needed, it is readily available and a portion of the contents might be easily dispensed.
  • the required medicament may be administered by the patient and the attack lessened and relieved.
  • the contents of the container are not dispensed at one time but, rather, over a period of time depending upon the frequency and severity of attacks.
  • a patient may carry such a container in a pocketbook, purse or pocket for weeks and even months, before the contents of the container are exhausted.
  • the medicament and propellant When not in use, the medicament and propellant are maintained under pressure in the container. Just before the contents are exhausted, the spray discharged from the container decreases, indicating to the patient that a new container is required. This might occur weeks, and even months, after such container has been placed in use.
  • the medicament and propellant are packaged in a pressure tight container of metal or other material and the container is provided with a valve.
  • a dispenser having a nozzle into which the container valve is inserted and, usually, the dispenser is provided with a head through which the spray, from the container, is dispensed.
  • Such dispenser is usually purchased by the patient with the initial container of medicament and propellant. When the contents of the container are exhausted, the dispenser is removed, the exhausted container is thrown away and a new container, purchased separately, is inserted in the dispenser.
  • the nozzle and head are situated in a head at the top of the dispenser and the dispenser is provided with a skirt that extends downwardly from the head.
  • the dispenser head is provided with a boss into which the valve stem on the container is inserted.
  • the boss frictionally grips and locks the container in the dispenser.
  • Other locking means, such as detents, recesses, and the like, on the dispenser and container may be employed.
  • the container is inserted in the dispenser through the open bottom of the skirt, the valve stem on the container is aligned with the opening in the boss in the dispenser head and the stem is pushed into the boss so that the stem is frictionally gripped by the boss to hold the container in the dispenser.
  • the dispenser skirt extends downward along the container body and one side of the skirt, at the lower end, is cutaway so that, by placing one finger on the bottom of the container, at the skirt recess, and another finger on the dispenser head, the container can be pressed into the dispenser to open the container valve and discharge a spray through the dispenser nozzle.
  • the cutaway at the skirt bottom also allows the container, when empty, to be pulled out so that a new container can be substituted.
  • the skirt extends beyond the lower end of the container and is rounded so that, if the dispenser, with the container therein, is placed on a table with the valve end up, the dispenser will fall over. In this way, the possibility of drainage of the metered charge out of the metering valve is avoided.
  • the nozzle hood is pivotally mounted on the dispenser head.
  • the hood prevents dust, dirt, and the like, from entering the dispenser head thus assuring that the head, and nozzle therein, will not become dirty and clogged.
  • the head engages the end of the container to prevent the container from being accidentally pushed into the dispenser and the valve from being accidentally opened to discharge the container contents.
  • the hood forms, with the dispenser head, an air passage through which air can enter the dispenser head, receive the metered spray of medication and discharge the mixture of medication and air to the patient.
  • the container When inserted and locked in the dispenser, the container, except where the dispenser skirt is cutaway, is housed within the skirt.
  • the container is protected, when in a pocketbook, purse or pocket, from being accidentally separated from the dispenser. This along with the engagement of the closed head with the container end, prevents accidental discharge and assures that, when needed by the patient, spray will be available.
  • the flow of air into the dispenser head and the discharge thereof through the nozzle head with the metered amount of medication assures that the patient using the dispenser will receive the prescribed medication.
  • FIG. 1 is a perspective side elevational view of the dispensing device
  • FIG. 2 is a sectional view of FIG. I taken along line 22;
  • FIG. 3 is a sectional view of the dispenser taken along line 3-3 of FIG. 2;
  • FIG. 4 is a sectional view of the valve line 44 of FIG. 2.
  • a conventional pressure container for the self-propelling composition, which container can be made of material such as steel, aluminum, etc.
  • the valve has a valve stem 6, with a passage therethrough, which when pushed into the container, opens the valve to discharge a metered amount of medication and, when released, permits the valve to close and recharge.
  • the dispenser to which the instant invention is particularly directed, includes head portion, generally designated 10, and skirt 12, extending downward from head 10.
  • skirt 12 is cylindrical to receive the cylindrical body of container 2 but may be of any shape to conform with the shape of the container, for example, rectangular, elliptical, etc.
  • skirt 12 is open and is cutaway at I4, to expose a portion or the container side for purposes more apparent hereinafter.
  • the lower end of skirt 12, where not cutaway, extends downward beyond the container end and is rounded at 16.
  • Nozzle 26 in boss 24, faces open side 34 of head between walls 36, 38.
  • Nozzle hood 40 having a front wall 42 and a rear wall 44, when the hood is closed, is pivotally mounted by pivot 46, 47, on hood sidewalls 49, 51. Pivots 46, 47, project into recess in walls 36, 38 of open side 34.
  • wall 44 is adjacent neck 4 of container 2, with the end of wall 44 above the top of container 2, for purposes more apparent hereinafter.
  • hood 40 When hood 40 is closed, wall 42 forms a closure over open side 34 of head 10.
  • Hood 40 is open at its end 48 and has an opening 50 at its opposite end which, when the hood is open to the phantom line in FIG. 2, is aligned with nozzle 26.
  • Dispenser 10 may be made of any suitable material but, preferably, is molded from rigid or semirigid plastic.
  • Container 2 is inserted through the open end of skirt 12, valve end forward, valve stem 6 is aligned with passageway 28 and the container is pushed into the dispenser. With hood 40 closed, at the top of the container abuts the end of hood wall 44, and prevents the container from being moved further into the dispenser to open the valve and discharge the container contents.
  • Skirt 12 extending downward along the container, prevents container 2 from being jarred or displaced, relative to the dispenser. Furthermore, the end of the skirt and the end of hood wall 44 prevent container 2 from being pushed into the dispenser to open the container valve.
  • the dispenser When the patient requires the medicament, the dispenser, with the container therein, is withdrawn from the pocketbook, purse or pocket, and hood 40 is flipped open to the phantom line of FIG. 2.
  • the patient can then place one finger in recess 32 on the top of head 10 and another finger on the bottom of the container at cutaway 14 in skirt l2 and, by pushing the container into the dispenser, open the -valve and discharge a metered amount of spray through nozzle 26 and into the air moving through hood opening 50 and the open end of hood 40.
  • the patient can reclose hood 40 and returns the dispenser, with the container therein, to the patient's pocketbook, purse, pocket or wherever else the patient might select to carry the dispenser until use is again required.
  • hood 40 when closed, wall 42 of hood 40 forms a closure over open side 34 of dispenser hood 10 but, when open, hood 40 occupies only the upper portion of open side 34. Thus, below hood 40, with hood 40 open, air can pass into head 10 of the dispenser.
  • Open end 48 of hood 40 is in or relatively close to the patient's mouth. Because the top, bottom and side of hood 40 are closed, and open end 48 of hood 40 is in or in close proximity to the patients mouth, little, if any, of the medicament is lost to the atmosphere irrespective of whether the dispenser is used indoors or out of doors. This is of particular importance to administration of the medicament.
  • the end of the empttylcontainer is Edinburghgiby finger at cutout l4 and, while holding e dispenser, con ner 2 IS pulled out of the dispenser.
  • the empty container is thrown away and a new container is inserted through the open end of skirt l2 and pushed into the dispenser. Empty containers can be removed and new container can be inserted in the container any number of times.
  • a dispenser as recited in claim 1, in which said means on said hood for engaging the end of a container is said inner wall of said hood when said hood is closed.
  • a dispenser as recited in claim I, in which said skirt portion extends downward beyond the end of a container inserted therein.
  • a dispenser as recited in claim 3, in which said skirt portion extending downward beyond the end of a container inserted therein is cutaway at one side of its lower end for exposing the bottom and a portion of one side of the container.
  • a dispenser as recited in claim 4, in which the bottom of said skirt portion extending downward beyond the end of the container is rounded.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Nozzles (AREA)
US883752A 1969-12-10 1969-12-10 Aerosol inhaler with flip-up nozzle Expired - Lifetime US3622053A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88375269A 1969-12-10 1969-12-10

Publications (1)

Publication Number Publication Date
US3622053A true US3622053A (en) 1971-11-23

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Application Number Title Priority Date Filing Date
US883752A Expired - Lifetime US3622053A (en) 1969-12-10 1969-12-10 Aerosol inhaler with flip-up nozzle

Country Status (9)

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US (1) US3622053A (enrdf_load_stackoverflow)
JP (1) JPS4933050B1 (enrdf_load_stackoverflow)
CA (1) CA948599A (enrdf_load_stackoverflow)
CH (1) CH515157A (enrdf_load_stackoverflow)
DE (1) DE2060583A1 (enrdf_load_stackoverflow)
DK (1) DK129392B (enrdf_load_stackoverflow)
FR (1) FR2073152A5 (enrdf_load_stackoverflow)
GB (1) GB1333438A (enrdf_load_stackoverflow)
NL (1) NL7017959A (enrdf_load_stackoverflow)

Cited By (68)

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USD248046S (en) * 1977-06-23 1978-05-30 Tetsuya Tada Sprayer with a swingable-nestable nozzle
US4114615A (en) * 1975-12-12 1978-09-19 Aktiebolaget Draco Aerosol inhalation device
US4114811A (en) * 1977-04-12 1978-09-19 Ciba-Geigy Corporation Spray dispenser with easily actuable mouthpiece
US4424920A (en) 1980-06-17 1984-01-10 Canyon Corporation Push-button type sprayer
US4456007A (en) * 1980-12-12 1984-06-26 Combi Co., Ltd. Inhaler
US4509515A (en) * 1982-02-23 1985-04-09 Fisons Plc Inhalation device
USD286816S (en) 1984-01-30 1986-11-18 Glaxo Group Limited Dispenser aid for aerosol containers
US4805812A (en) * 1987-12-11 1989-02-21 Delshar Industries, Inc. Spray can actuation device with locking mechanism
US4819832A (en) * 1986-08-18 1989-04-11 The English Glass Company Limited Pump type dispenser with swivellable nozzle for locking the pump
US4969578A (en) * 1988-05-09 1990-11-13 Bespak Plc Dispensing apparatus
US5611444A (en) * 1989-02-03 1997-03-18 Senetics, Inc. Indicator device responsive to axial force
EP0937505A1 (fr) * 1998-02-24 1999-08-25 L'oreal Ensemble de conditionnement et de distribution, et utilisation d'un tel ensemble pour le conditionnement d'un produit cosmétique, pharmaceutique ou dermopharmaceutique
US6032835A (en) * 1993-01-19 2000-03-07 Glaxo Group Ltd. Aerosol dispenser and method
WO2000018458A1 (en) * 1998-09-26 2000-04-06 Glaxo Group Limited Inhalation device
WO2000018456A1 (en) * 1998-09-26 2000-04-06 Glaxo Group Limited Inhalation device
US20030066525A1 (en) * 1998-11-25 2003-04-10 Chiesi Farmaceutici S.P.A. Pressurised metered dose inhalers (MDI)
US6575162B1 (en) 1998-09-26 2003-06-10 Smithkline Beecham Corporation Inhalation device
US6612302B1 (en) 1998-09-26 2003-09-02 Smithkline Beecham Corporation Inhalation device
US20030190289A1 (en) * 2000-05-12 2003-10-09 David Lewis Formulations containing a glucocorticoid drug for the treatment of bronchopulmonary diseases
US20030190287A1 (en) * 1997-06-13 2003-10-09 Chiesi Farmaceutici S.P.A. Pharaceutical aerosol composition
US20030218029A1 (en) * 2002-05-24 2003-11-27 Harvey Brody Spray can holding and actuating device
US20040033201A1 (en) * 1999-06-18 2004-02-19 3M Innovative Properties Company Process for making chemically stable C-17/21 OH 20-ketosteroid aerosol products
US20040139964A1 (en) * 2003-01-17 2004-07-22 Langford Stanley C. Actuation inhibitor for metered dose inhalers
US20040222245A1 (en) * 2003-04-24 2004-11-11 Lindal Ventil Gmbh Spraying cap
US20050034720A1 (en) * 2000-01-07 2005-02-17 Gaetano Brambilla Aerosol inhaler
US6860412B1 (en) * 1993-01-19 2005-03-01 Glaxo Group Limited Aerosol dispenser with ultrasonically welded closure and method of making
US20050154013A1 (en) * 2002-03-01 2005-07-14 Chiesi Farmaceutici S.P.A. Pressurised metered dose inhalers containing solutions of beta-2 agonists
US20050163722A1 (en) * 2001-07-02 2005-07-28 Chiesi Farmaceutici S.P.A. Optimised formulation of tobramycin for aerosolization
WO2005087299A1 (en) * 2004-03-10 2005-09-22 Glaxo Group Limited A dispensing device
US6964759B2 (en) 2000-02-22 2005-11-15 Chiesi Farmaceutici S.P.A. Formulations containing an anticholinergic drug for the treatment of chronic obstructive pulmonary disease
US6967017B1 (en) 1999-07-23 2005-11-22 Chiesi Farmaceutici S.P.A. Formulations of steroid solutions for inhalatory administration
US7018618B2 (en) 2000-05-22 2006-03-28 Chiesi Farmaceutici S.P.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
US20070181120A1 (en) * 2005-11-22 2007-08-09 Andrew Wright Aerosol dispensing apparatus
US20070284383A1 (en) * 2006-05-26 2007-12-13 Andrew Wright Dispensing apparatus
US7381402B2 (en) 2004-02-27 2008-06-03 Chiesi Farmaceutici S.P.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
US20080127970A1 (en) * 1999-07-23 2008-06-05 Mannkind Corporation Unit Dose Capsules and Dry Powder Inhaler
US20090241949A1 (en) * 2008-03-27 2009-10-01 Smutney Chad C Dry powder inhalation system
CN1950122B (zh) * 2004-03-10 2010-09-29 葛兰素集团有限公司 分配设备
US20110049191A1 (en) * 2009-01-16 2011-03-03 Colgate-Palmolive Company Dispensing container
US8291898B2 (en) 2006-05-26 2012-10-23 Consort Medical Plc Dispensing apparatus
US8950397B2 (en) 1999-07-23 2015-02-10 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US9192675B2 (en) 2008-06-13 2015-11-24 Mankind Corporation Dry powder inhaler and system for drug delivery
US9220687B2 (en) 2008-12-29 2015-12-29 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US9233159B2 (en) 2011-10-24 2016-01-12 Mannkind Corporation Methods and compositions for treating pain
US9241903B2 (en) 2006-02-22 2016-01-26 Mannkind Corporation Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
US9283193B2 (en) 2005-09-14 2016-03-15 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
US9346766B2 (en) 2004-08-20 2016-05-24 Mannkind Corporation Catalysis of diketopiperazine synthesis
US9364436B2 (en) 2011-06-17 2016-06-14 Mannkind Corporation High capacity diketopiperazine microparticles and methods
US9364619B2 (en) 2008-06-20 2016-06-14 Mannkind Corporation Interactive apparatus and method for real-time profiling of inhalation efforts
US9630930B2 (en) 2009-06-12 2017-04-25 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
US9662461B2 (en) 2008-06-13 2017-05-30 Mannkind Corporation Dry powder drug delivery system and methods
US9675674B2 (en) 2004-08-23 2017-06-13 Mannkind Corporation Diketopiperazine salts for drug delivery and related methods
US9700690B2 (en) 2002-03-20 2017-07-11 Mannkind Corporation Inhalation apparatus
US9706944B2 (en) 2009-11-03 2017-07-18 Mannkind Corporation Apparatus and method for simulating inhalation efforts
US9801925B2 (en) 1999-06-29 2017-10-31 Mannkind Corporation Potentiation of glucose elimination
US9802012B2 (en) 2012-07-12 2017-10-31 Mannkind Corporation Dry powder drug delivery system and methods
US9925144B2 (en) 2013-07-18 2018-03-27 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
US9943571B2 (en) 2008-08-11 2018-04-17 Mannkind Corporation Use of ultrarapid acting insulin
US9983108B2 (en) 2009-03-11 2018-05-29 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10342938B2 (en) 2008-06-13 2019-07-09 Mannkind Corporation Dry powder drug delivery system
US10421729B2 (en) 2013-03-15 2019-09-24 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
US10506829B2 (en) 2016-02-26 2019-12-17 Freelander Innovations USA, LLC System and method for a vaporizer
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US10625034B2 (en) 2011-04-01 2020-04-21 Mannkind Corporation Blister package for pharmaceutical cartridges
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US11446127B2 (en) 2013-08-05 2022-09-20 Mannkind Corporation Insufflation apparatus and methods

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JPS52156644U (enrdf_load_stackoverflow) * 1976-05-21 1977-11-28
FR2626254B1 (fr) * 1988-01-27 1990-07-06 Valois Sa Poussoir-etui avec systeme de garantie
IT233948Y1 (it) * 1994-07-20 2000-02-16 Plastiape Spa Dispositivo erogatore tascabile,particolrmente studiato per immettere nel cavo orale sostanze medicamentose nebulizzate
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Cited By (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4114615A (en) * 1975-12-12 1978-09-19 Aktiebolaget Draco Aerosol inhalation device
US4114811A (en) * 1977-04-12 1978-09-19 Ciba-Geigy Corporation Spray dispenser with easily actuable mouthpiece
USD248046S (en) * 1977-06-23 1978-05-30 Tetsuya Tada Sprayer with a swingable-nestable nozzle
US4424920A (en) 1980-06-17 1984-01-10 Canyon Corporation Push-button type sprayer
US4456007A (en) * 1980-12-12 1984-06-26 Combi Co., Ltd. Inhaler
US4509515A (en) * 1982-02-23 1985-04-09 Fisons Plc Inhalation device
USD286816S (en) 1984-01-30 1986-11-18 Glaxo Group Limited Dispenser aid for aerosol containers
US4819832A (en) * 1986-08-18 1989-04-11 The English Glass Company Limited Pump type dispenser with swivellable nozzle for locking the pump
US4805812A (en) * 1987-12-11 1989-02-21 Delshar Industries, Inc. Spray can actuation device with locking mechanism
US4969578A (en) * 1988-05-09 1990-11-13 Bespak Plc Dispensing apparatus
US5611444A (en) * 1989-02-03 1997-03-18 Senetics, Inc. Indicator device responsive to axial force
US6860412B1 (en) * 1993-01-19 2005-03-01 Glaxo Group Limited Aerosol dispenser with ultrasonically welded closure and method of making
US6032835A (en) * 1993-01-19 2000-03-07 Glaxo Group Ltd. Aerosol dispenser and method
US7601336B2 (en) 1997-06-13 2009-10-13 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
US20090311196A1 (en) * 1997-06-13 2009-12-17 Chiesi Farmaceutici S.P.A Pharmaceutical aerosol composition
US20040062720A1 (en) * 1997-06-13 2004-04-01 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
US8420058B2 (en) 1997-06-13 2013-04-16 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
US20030206870A1 (en) * 1997-06-13 2003-11-06 Chiesi Farmaceutici S.P.A. Pharaceutical aerosol composition
US20030190287A1 (en) * 1997-06-13 2003-10-09 Chiesi Farmaceutici S.P.A. Pharaceutical aerosol composition
EP0937505A1 (fr) * 1998-02-24 1999-08-25 L'oreal Ensemble de conditionnement et de distribution, et utilisation d'un tel ensemble pour le conditionnement d'un produit cosmétique, pharmaceutique ou dermopharmaceutique
FR2775258A1 (fr) * 1998-02-24 1999-08-27 Oreal Ensemble de conditionnement et de distribution, et utilisation d'un tel ensemble pour le conditionnement d'un produit cosmetique, pharmaceutique ou dermopharmaceutique
US6053363A (en) * 1998-02-24 2000-04-25 L'oreal Packaging and dispensing assembly for a cosmetic, pharmaceutical or dermo-pharmaceutical product
US6612302B1 (en) 1998-09-26 2003-09-02 Smithkline Beecham Corporation Inhalation device
US6575162B1 (en) 1998-09-26 2003-06-10 Smithkline Beecham Corporation Inhalation device
US6568389B1 (en) 1998-09-26 2003-05-27 Smithkline Beecham Corporation Inhalation device
WO2000018458A1 (en) * 1998-09-26 2000-04-06 Glaxo Group Limited Inhalation device
WO2000018456A1 (en) * 1998-09-26 2000-04-06 Glaxo Group Limited Inhalation device
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Also Published As

Publication number Publication date
DE2060583A1 (de) 1971-06-16
NL7017959A (enrdf_load_stackoverflow) 1971-06-14
FR2073152A5 (fr) 1971-09-24
GB1333438A (en) 1973-10-10
CA948599A (en) 1974-06-04
JPS4933050B1 (enrdf_load_stackoverflow) 1974-09-04
DK129392B (da) 1974-10-07
CH515157A (de) 1971-11-15
DK129392C (enrdf_load_stackoverflow) 1975-02-24

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