US3588920A - Surgical vascular prostheses formed of polyester fiber paper - Google Patents
Surgical vascular prostheses formed of polyester fiber paper Download PDFInfo
- Publication number
- US3588920A US3588920A US855585A US3588920DA US3588920A US 3588920 A US3588920 A US 3588920A US 855585 A US855585 A US 855585A US 3588920D A US3588920D A US 3588920DA US 3588920 A US3588920 A US 3588920A
- Authority
- US
- United States
- Prior art keywords
- polyester fiber
- prostheses
- fiber paper
- paper
- microns
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000835 fiber Substances 0.000 title abstract description 23
- 229920000728 polyester Polymers 0.000 title abstract description 23
- 230000002792 vascular Effects 0.000 title abstract description 16
- 230000035876 healing Effects 0.000 abstract description 4
- 239000000853 adhesive Substances 0.000 description 7
- 230000001070 adhesive effect Effects 0.000 description 7
- 241001465754 Metazoa Species 0.000 description 5
- 239000007943 implant Substances 0.000 description 5
- 239000005020 polyethylene terephthalate Substances 0.000 description 5
- 229920004934 Dacron® Polymers 0.000 description 4
- 230000004927 fusion Effects 0.000 description 4
- 238000002844 melting Methods 0.000 description 4
- 230000008018 melting Effects 0.000 description 4
- 210000001367 artery Anatomy 0.000 description 3
- 239000004744 fabric Substances 0.000 description 3
- 229920001651 Cyanoacrylate Polymers 0.000 description 2
- 206010061876 Obstruction Diseases 0.000 description 2
- -1 Vinyon-N Polymers 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000000704 physical effect Effects 0.000 description 2
- 229920006122 polyamide resin Polymers 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 238000009958 sewing Methods 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 229920002972 Acrylic fiber Polymers 0.000 description 1
- 101100129922 Caenorhabditis elegans pig-1 gene Proteins 0.000 description 1
- 101100520057 Drosophila melanogaster Pig1 gene Proteins 0.000 description 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 210000000709 aorta Anatomy 0.000 description 1
- 210000002376 aorta thoracic Anatomy 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 230000003176 fibrotic effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 229920000768 polyamine Polymers 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 239000012209 synthetic fiber Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- D—TEXTILES; PAPER
- D21—PAPER-MAKING; PRODUCTION OF CELLULOSE
- D21H—PULP COMPOSITIONS; PREPARATION THEREOF NOT COVERED BY SUBCLASSES D21C OR D21D; IMPREGNATING OR COATING OF PAPER; TREATMENT OF FINISHED PAPER NOT COVERED BY CLASS B31 OR SUBCLASS D21G; PAPER NOT OTHERWISE PROVIDED FOR
- D21H13/00—Pulp or paper, comprising synthetic cellulose or non-cellulose fibres or web-forming material
- D21H13/10—Organic non-cellulose fibres
- D21H13/20—Organic non-cellulose fibres from macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- D21H13/24—Polyesters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
Definitions
- polyester fiber paper having a thickness of from about 64 microns to about 254 microns.
- the mechanical handling properties are excellent and the residual patency of the implanted prostheses following healing is superior to polyester prostheses having a woven or knit structure.
- This invention relates to prostheses constructed to maintain an open lumen when placed in an animal body, particularly in the human body. More particularly, this invention relates to vascular implants for surgical use in the repair and replacement of vessels and tracts in human and animal bodies.
- Synthetic fibers such as Vinyon-N, nylon, Orlon, Dacron, Teflon, and Ivalon have been woven and knitted into tubes and other suitable shapes, for use as arteries, veins, ducts, esophagi and the like.
- an artificial graft must meet a number of standards in order to be of value.
- the graft must have certain physical properties such that it can be readily handled and manipulated during the specific surgery calling for its use. It must be flexible, for such is essential during an operation when time is critical and the graft must be accommodated to the artery, vein or the like to which it is being secured. It is sometimes necessary in surgery to bend a device or graft either around or under a body organ.
- An essential feature is that the graft be suificiently rigid, though bendable, to allow for flexing without collapse and closing of the lumen thereof. If the graft does not have such strength, there is ever present the danger that when bent or flexed acutely in the body the lumen would collapse, leading to fatality.
- a suitable prostheses for the body should be non-toxic, flexible and porous.
- the ideal prostheses should retain its strength permanently in intimate contact with the body fluids and should be readily accepted and incorporated into the tissues. Porosity is an important characteristic of such a prosthesis to avoid the formation of fluid pockets and to promote the growth through the fabric of repair tissue. Proper merging of the fabric with the body structure is also essential.
- the fibers are randomly arranged and bonded together to form a non-woven, paper-like sheet.
- the structure may be stabilized by fusion of some of the polyester fibers to cause adhesion.
- various adhesives may be used for this purpose, i.e., a polyamide resin produced by the condensation of a polycarboxylic acid with polyamine (Versamid).
- an adhesive it must be applied sparingly to spot-weld the polyester fibers at spaced intervals throughout the area of the paper sheet so as not to decrease unduly the porosity of the fabric.
- a polyamide resin it is heatcured to polymerize and set the adhesive.
- a further object of the present invention is to provide a gossamer tube of high porosity. Still another object is to form artificial vascular parts for an animal body suitable for use as a replacement for damaged arteries.
- FIG. 1 is a perspective view of a Dacron paper tube embodying the invention
- FIG. 2 is a perspective view of the Dacron paper vascular implant of bifurcated form
- FIG. 3 is a cross-section of a vascular prostheses on the line 3--3 of FIG. 1;
- FIG. 4 is a longitudinal cross-section on the line 4-4 of FIG. 1;
- FIG. 5 is a cross-section of the tube shown in FIGS. 1 and 4 when in a crimped condition.
- the paper that is used to construct the prostheses of the present invention may consist essentially of polyester (polyethylene terephthalate) fibers of indefinite length.
- the paper is desirably between about 64 microns and 254 microns in thickness.
- one may include in the polyester fi-ber composition a small amount (1-4%) of a polyester fiber having a melting point that is substantially below the melting point of the polyester fibers that con stitute the major portion of the paper composition.
- the paper sheet after formation, is heated for a short period of time to the fusion temperature of the low melting polyester fibers, but below the fusion temperature of the higher melting polyester fibers, and then cooled to room temperature.
- the vascular prostheses of the present invention may be constructed, as best shown in FIG. 1, by rolling an oblong sheet to form a tube 10 and cementing the longitudinal seam 11 with a suitable adhesive.
- Adhesives that may be used for this purpose are the Z-cyanoacrylic esters such as methyl Z-cyanoacrylate and isobutyl Z-cyanoacrylate.
- the longitudinal seams may be secured by sewing with a polyester fiber thread, or by heat sealing.
- Bifurcated structures of the type shown in FIG. 2 may be manufactured by making a small longitudinal cut 12 in the wall of a tube and joining thereto one end of a second tube 13 with an appropriate adhesive or by sewing, or heat sealing.
- the tubes of the present invention may be crimped to allow for flexing and bending without collapse and closing of the lumen, by placing the uncrimped tube on a glass mandrel of slightly smaller diameter and compressing the tube longitudinally. The glass mandrel with the compressed tube thereon is then heat-set at a temperature slightly below the fusion temperature of the polyester fibers that are present in the paper, and permitted to cool to room temperature. After cooling, a crimped prostheses having the structure illustrated in FIG. may be removed from the mandrel.
- Paper polyester fiber tubes constructed in accordance with the present invention exhibit excellent mechanical and physical properties and may be sutured quite like normal aorta. Tests have been performed by implantation into the thoracic aorta of growing pigs for periods of six months.
- the prostheses demonstrate in general excellent healing properties that compare well with the best healing prostheses of knitted and woven fabrications and show no incidence of obstruction that may sometimes result from the secondary deposition of thrombus upon the inner surface.
- the general observations with respect to fibrotic and cellular reaction, stenosis, and obstruction is summarized in the following table.
- the articles formed as described herein are useful as tubular grafts. They have desired characteristics as revealed by their maneuverability and flexing quality and capability of maintaining an open lumen when flexed. In addition, they have the desired feature of porosity as well as integrating Well with body tissue.
- a tubular vascular prosthesis formed from randomly arranged polyester fibers bonded together to form a polyester fiber paper implant suitable for implanting in the human or animal body, said prosthesis characterized by having a porosity to water of from about 550 cc. to 8,000 cc. per minute per square centimeter as measured on the Wesolowski scale and having a wall thickness of from about 64 microns to about 254 microns.
- the vascular prostheses of claim 1 wherein the porosity is 8,000 cc. per minute per square centimeter and the wall thickness is 64 microns.
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85558569A | 1969-09-05 | 1969-09-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
US3588920A true US3588920A (en) | 1971-06-29 |
Family
ID=25321621
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US855585A Expired - Lifetime US3588920A (en) | 1969-09-05 | 1969-09-05 | Surgical vascular prostheses formed of polyester fiber paper |
Country Status (5)
Country | Link |
---|---|
US (1) | US3588920A (enrdf_load_stackoverflow) |
DE (1) | DE2025358A1 (enrdf_load_stackoverflow) |
FR (1) | FR2060524A5 (enrdf_load_stackoverflow) |
GB (1) | GB1265246A (enrdf_load_stackoverflow) |
NL (1) | NL7009030A (enrdf_load_stackoverflow) |
Cited By (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3843974A (en) * | 1972-01-05 | 1974-10-29 | Us Health Education & Welfare | Intimal lining and pump with vertically drafted webs |
US3878565A (en) * | 1971-07-14 | 1975-04-22 | Providence Hospital | Vascular prosthesis with external pile surface |
US3902198A (en) * | 1974-05-20 | 1975-09-02 | Gore & Ass | Method of replacing a body part with expanded porous polytetrafluoroethylene |
US3908201A (en) * | 1972-06-30 | 1975-09-30 | Ici Ltd | Prosthetics |
US4042978A (en) * | 1972-06-30 | 1977-08-23 | Imperial Chemical Industries Limited | Prosthetics |
US4130904A (en) * | 1977-06-06 | 1978-12-26 | Thermo Electron Corporation | Prosthetic blood conduit |
US4191218A (en) * | 1975-05-07 | 1980-03-04 | Albany International Corp. | Fabrics for heart valve and vascular prostheses and methods of fabricating same |
EP0043555A1 (en) * | 1980-07-07 | 1982-01-13 | Teijin Limited | Paper-like polyester fiber sheet and process for producing the same |
US4573471A (en) * | 1984-07-09 | 1986-03-04 | Rudner Merritt A | Prosthetic apparatus for surgical anastomosis |
US4671797A (en) * | 1984-09-21 | 1987-06-09 | Vrandecic Pedero Mario O | Heterologous arterial biograft and biological material treating process |
US4759748A (en) * | 1986-06-30 | 1988-07-26 | Raychem Corporation | Guiding catheter |
US4870966A (en) * | 1988-02-01 | 1989-10-03 | American Cyanamid Company | Bioabsorbable surgical device for treating nerve defects |
US5258027A (en) * | 1991-01-24 | 1993-11-02 | Willy Rusch Ag | Trachreal prosthesis |
US5697970A (en) * | 1994-08-02 | 1997-12-16 | Meadox Medicals, Inc. | Thinly woven flexible graft |
US5700287A (en) * | 1992-12-11 | 1997-12-23 | W. L. Gore & Associates, Inc. | Prosthetic vascular graft with deflectably secured fibers |
WO1999033403A1 (en) | 1997-12-31 | 1999-07-08 | Kensey Nash Corporation | Bifurcated connector system for coronary bypass grafts |
US6017352A (en) * | 1997-09-04 | 2000-01-25 | Kensey Nash Corporation | Systems for intravascular procedures and methods of use |
US6030395A (en) * | 1997-05-22 | 2000-02-29 | Kensey Nash Corporation | Anastomosis connection system |
US6063114A (en) * | 1997-09-04 | 2000-05-16 | Kensey Nash Corporation | Connector system for vessels, ducts, lumens or hollow organs and methods of use |
US6436135B1 (en) | 1974-10-24 | 2002-08-20 | David Goldfarb | Prosthetic vascular graft |
US20030093140A1 (en) * | 1987-12-08 | 2003-05-15 | W. Henry Wall | Method of implanting a sleeve in a lumen |
US20050113910A1 (en) * | 2002-01-04 | 2005-05-26 | David Paniagua | Percutaneously implantable replacement heart valve device and method of making same |
US20050267566A1 (en) * | 2003-03-26 | 2005-12-01 | Robert Rioux | Longitudinally expanding medical device |
US20090163936A1 (en) * | 2007-12-21 | 2009-06-25 | Chunlin Yang | Coated Tissue Engineering Scaffold |
US20100100170A1 (en) * | 2008-10-22 | 2010-04-22 | Boston Scientific Scimed, Inc. | Shape memory tubular stent with grooves |
US20100227096A1 (en) * | 2009-03-09 | 2010-09-09 | Georg Fischer Jrg Ag | Method for producing a tubular hollow body, and tubular hollow body |
US8361144B2 (en) | 2010-03-01 | 2013-01-29 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve and methods associated therewith |
US9119738B2 (en) | 2010-06-28 | 2015-09-01 | Colibri Heart Valve Llc | Method and apparatus for the endoluminal delivery of intravascular devices |
EP3011936A1 (en) * | 2011-01-06 | 2016-04-27 | Humacyte | Tissue-engineered constructs |
US9737400B2 (en) | 2010-12-14 | 2017-08-22 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets |
CN107708612A (zh) * | 2015-06-02 | 2018-02-16 | 株式会社Adeka | 源自生物体的组织的片材、由该片材得到的管状结构体以及包含该管状结构体的人工血管 |
US11395726B2 (en) | 2017-09-11 | 2022-07-26 | Incubar Llc | Conduit vascular implant sealing device for reducing endoleaks |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1527592A (en) * | 1974-08-05 | 1978-10-04 | Ici Ltd | Wound dressing |
US4340091A (en) * | 1975-05-07 | 1982-07-20 | Albany International Corp. | Elastomeric sheet materials for heart valve and other prosthetic implants |
GB1577221A (en) * | 1976-02-04 | 1980-10-22 | Ici Ltd | Vascular prosthesis |
DE2806030C2 (de) * | 1978-02-14 | 1984-02-02 | B. Braun Melsungen Ag, 3508 Melsungen | Verfahren zur Herstellung einer schlauchförmigen Blutgefäßprothese |
DE3477464D1 (en) * | 1983-06-06 | 1989-05-03 | Kanegafuchi Chemical Ind | Artificial vessel and process for preparing the same |
DE3478192D1 (en) * | 1983-06-06 | 1989-06-22 | Kanegafuchi Chemical Ind | Artificial vessel and process for preparing the same |
EP0157178B1 (en) * | 1984-03-01 | 1988-11-30 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Artificial vessel and process for preparing the same |
GB8422530D0 (en) * | 1984-09-06 | 1984-10-10 | Shirley Inst | Production of porous tubes |
DE3666530D1 (en) * | 1985-08-26 | 1989-11-30 | Kanegafuchi Chemical Ind | Artificial vessel |
JPS63209647A (ja) * | 1987-02-26 | 1988-08-31 | 鐘淵化学工業株式会社 | 人工血管 |
SE8802414D0 (sv) * | 1988-06-27 | 1988-06-28 | Astra Meditec Ab | Nytt kirurgiskt material |
US5641505A (en) * | 1988-06-27 | 1997-06-24 | Astra Tech Aktiebolag | Porous flexible sheet for tissue separation |
ATE511816T1 (de) * | 2003-03-31 | 2011-06-15 | Teijin Ltd | Verbund aus trägersubstrat und kollagen und verfahren zur herstellung eines trägersubstrats und verbunds |
EP2314739A1 (en) * | 2009-10-22 | 2011-04-27 | Gyeong-Man Kim | Anti-migration casing for transponders |
-
1969
- 1969-09-05 US US855585A patent/US3588920A/en not_active Expired - Lifetime
-
1970
- 1970-05-18 GB GB1265246D patent/GB1265246A/en not_active Expired
- 1970-05-23 DE DE19702025358 patent/DE2025358A1/de active Pending
- 1970-06-19 FR FR7022651A patent/FR2060524A5/fr not_active Expired
- 1970-06-19 NL NL7009030A patent/NL7009030A/xx not_active Application Discontinuation
Cited By (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3878565A (en) * | 1971-07-14 | 1975-04-22 | Providence Hospital | Vascular prosthesis with external pile surface |
US3843974A (en) * | 1972-01-05 | 1974-10-29 | Us Health Education & Welfare | Intimal lining and pump with vertically drafted webs |
US3908201A (en) * | 1972-06-30 | 1975-09-30 | Ici Ltd | Prosthetics |
US4042978A (en) * | 1972-06-30 | 1977-08-23 | Imperial Chemical Industries Limited | Prosthetics |
US3902198A (en) * | 1974-05-20 | 1975-09-02 | Gore & Ass | Method of replacing a body part with expanded porous polytetrafluoroethylene |
US6436135B1 (en) | 1974-10-24 | 2002-08-20 | David Goldfarb | Prosthetic vascular graft |
US4191218A (en) * | 1975-05-07 | 1980-03-04 | Albany International Corp. | Fabrics for heart valve and vascular prostheses and methods of fabricating same |
US4130904A (en) * | 1977-06-06 | 1978-12-26 | Thermo Electron Corporation | Prosthetic blood conduit |
EP0043555A1 (en) * | 1980-07-07 | 1982-01-13 | Teijin Limited | Paper-like polyester fiber sheet and process for producing the same |
US4573471A (en) * | 1984-07-09 | 1986-03-04 | Rudner Merritt A | Prosthetic apparatus for surgical anastomosis |
US4671797A (en) * | 1984-09-21 | 1987-06-09 | Vrandecic Pedero Mario O | Heterologous arterial biograft and biological material treating process |
US4759748A (en) * | 1986-06-30 | 1988-07-26 | Raychem Corporation | Guiding catheter |
US6974475B1 (en) | 1987-12-08 | 2005-12-13 | Wall W Henry | Angioplasty stent |
US20030093140A1 (en) * | 1987-12-08 | 2003-05-15 | W. Henry Wall | Method of implanting a sleeve in a lumen |
US4870966A (en) * | 1988-02-01 | 1989-10-03 | American Cyanamid Company | Bioabsorbable surgical device for treating nerve defects |
US5258027A (en) * | 1991-01-24 | 1993-11-02 | Willy Rusch Ag | Trachreal prosthesis |
US5700287A (en) * | 1992-12-11 | 1997-12-23 | W. L. Gore & Associates, Inc. | Prosthetic vascular graft with deflectably secured fibers |
US5697970A (en) * | 1994-08-02 | 1997-12-16 | Meadox Medicals, Inc. | Thinly woven flexible graft |
USRE40404E1 (en) | 1994-08-02 | 2008-06-24 | Maquet Cardiovascular, Llp | Thinly woven flexible graft |
US6030395A (en) * | 1997-05-22 | 2000-02-29 | Kensey Nash Corporation | Anastomosis connection system |
US6036705A (en) * | 1997-05-22 | 2000-03-14 | Kensey Nash Corporation | Anastomosis connection system and method of use |
US6056762A (en) * | 1997-05-22 | 2000-05-02 | Kensey Nash Corporation | Anastomosis system and method of use |
US6402767B1 (en) | 1997-05-22 | 2002-06-11 | Kensey Nash Corporation | Anastomosis connection system and method of use |
US7264624B2 (en) | 1997-09-04 | 2007-09-04 | Kensey Nash Corporation | Surgical connector systems and methods of use |
US7695483B2 (en) | 1997-09-04 | 2010-04-13 | Kensey Nash Corporation | Surgical connector systems and methods of use |
US6063114A (en) * | 1997-09-04 | 2000-05-16 | Kensey Nash Corporation | Connector system for vessels, ducts, lumens or hollow organs and methods of use |
US6923820B1 (en) | 1997-09-04 | 2005-08-02 | Kensey Nash Corporation | Surgical connector systems and methods of use |
US20050245946A1 (en) * | 1997-09-04 | 2005-11-03 | Nash John E | Surgical connector systems and methods of use |
US8377080B2 (en) | 1997-09-04 | 2013-02-19 | Kensey Nash Corporation | Surgical connector systems and methods of use |
US6017352A (en) * | 1997-09-04 | 2000-01-25 | Kensey Nash Corporation | Systems for intravascular procedures and methods of use |
US5922022A (en) * | 1997-09-04 | 1999-07-13 | Kensey Nash Corporation | Bifurcated connector system for coronary bypass grafts and methods of use |
US20070293881A1 (en) * | 1997-09-04 | 2007-12-20 | Nash John E | Surgical connector systems and methods of use |
US20100217290A1 (en) * | 1997-09-04 | 2010-08-26 | Nash John E | Surgical connector systems and methods of use |
WO1999033403A1 (en) | 1997-12-31 | 1999-07-08 | Kensey Nash Corporation | Bifurcated connector system for coronary bypass grafts |
US9554898B2 (en) | 2002-01-04 | 2017-01-31 | Colibri Heart Valve Llc | Percutaneous prosthetic heart valve |
US9610158B2 (en) | 2002-01-04 | 2017-04-04 | Colibri Heart Valve Llc | Percutaneously implantable replacement heart valve device and method of making same |
US9125739B2 (en) | 2002-01-04 | 2015-09-08 | Colibri Heart Valve Llc | Percutaneous replacement heart valve and a delivery and implantation system |
US20090030511A1 (en) * | 2002-01-04 | 2009-01-29 | David Paniagua | Percutaneously implantable replacement heart valve device and method of making same |
US20050113910A1 (en) * | 2002-01-04 | 2005-05-26 | David Paniagua | Percutaneously implantable replacement heart valve device and method of making same |
US8900294B2 (en) | 2002-01-04 | 2014-12-02 | Colibri Heart Valve Llc | Method of controlled release of a percutaneous replacement heart valve |
US8109995B2 (en) | 2002-01-04 | 2012-02-07 | Colibri Heart Valve Llc | Percutaneously implantable replacement heart valve device and method of making same |
US8308797B2 (en) | 2002-01-04 | 2012-11-13 | Colibri Heart Valve, LLC | Percutaneously implantable replacement heart valve device and method of making same |
US8790398B2 (en) | 2002-01-04 | 2014-07-29 | Colibri Heart Valve Llc | Percutaneously implantable replacement heart valve device and method of making same |
US9186248B2 (en) | 2002-01-04 | 2015-11-17 | Colibri Heart Valve Llc | Percutaneously implantable replacement heart valve device and method of making same |
US20050267566A1 (en) * | 2003-03-26 | 2005-12-01 | Robert Rioux | Longitudinally expanding medical device |
US7842098B2 (en) * | 2003-03-26 | 2010-11-30 | Boston Scientific Scimed, Inc. | Longitudinally expanding medical device |
US20090163936A1 (en) * | 2007-12-21 | 2009-06-25 | Chunlin Yang | Coated Tissue Engineering Scaffold |
US9980806B2 (en) | 2008-10-22 | 2018-05-29 | Boston Scientific Scimed, Inc. | Shape memory tubular stent with grooves |
US20100100170A1 (en) * | 2008-10-22 | 2010-04-22 | Boston Scientific Scimed, Inc. | Shape memory tubular stent with grooves |
US9724883B2 (en) | 2009-03-09 | 2017-08-08 | Georg Fischer Jrg Ag | Method for producing a tubular hollow body, and tubular hollow body |
US8652605B2 (en) * | 2009-03-09 | 2014-02-18 | Georg Fischer Jrg Ag | Method for producing a tubular hollow body, and tubular hollow body |
US20100227096A1 (en) * | 2009-03-09 | 2010-09-09 | Georg Fischer Jrg Ag | Method for producing a tubular hollow body, and tubular hollow body |
US8361144B2 (en) | 2010-03-01 | 2013-01-29 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve and methods associated therewith |
US9119738B2 (en) | 2010-06-28 | 2015-09-01 | Colibri Heart Valve Llc | Method and apparatus for the endoluminal delivery of intravascular devices |
US9737400B2 (en) | 2010-12-14 | 2017-08-22 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets |
US10973632B2 (en) | 2010-12-14 | 2021-04-13 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets |
EP3011936A1 (en) * | 2011-01-06 | 2016-04-27 | Humacyte | Tissue-engineered constructs |
CN107708612A (zh) * | 2015-06-02 | 2018-02-16 | 株式会社Adeka | 源自生物体的组织的片材、由该片材得到的管状结构体以及包含该管状结构体的人工血管 |
JP2020185432A (ja) * | 2015-06-02 | 2020-11-19 | 株式会社Adeka | 生体由来組織のシート、該シートから得られる管状構造体及び該管状構造体からなる人工血管 |
US11395726B2 (en) | 2017-09-11 | 2022-07-26 | Incubar Llc | Conduit vascular implant sealing device for reducing endoleaks |
Also Published As
Publication number | Publication date |
---|---|
NL7009030A (enrdf_load_stackoverflow) | 1971-03-09 |
GB1265246A (enrdf_load_stackoverflow) | 1972-03-01 |
FR2060524A5 (enrdf_load_stackoverflow) | 1971-06-18 |
DE2025358A1 (de) | 1971-06-16 |
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