US3494359A - Two compartment syringe with a single barrel - Google Patents

Two compartment syringe with a single barrel Download PDF

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Publication number
US3494359A
US3494359A US807690A US3494359DA US3494359A US 3494359 A US3494359 A US 3494359A US 807690 A US807690 A US 807690A US 3494359D A US3494359D A US 3494359DA US 3494359 A US3494359 A US 3494359A
Authority
US
United States
Prior art keywords
barrel
compartment
separator
syringe
plunger
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US807690A
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English (en)
Inventor
Eli A Zackheim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Silver Industries Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of US3494359A publication Critical patent/US3494359A/en
Assigned to SILVER INDUSTRIES, INC. reassignment SILVER INDUSTRIES, INC. ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: SILVER, JULES
Assigned to SILVER INDUSTRIES INC., A CORP. OF CT. reassignment SILVER INDUSTRIES INC., A CORP. OF CT. CONDITIONAL ASSIGNMENT (SEE DOCUMENT FOR DETAILS). Assignors: SILVER, JULES
Assigned to HARTFORD NATIONAL BANK AND TRUST COMPANY reassignment HARTFORD NATIONAL BANK AND TRUST COMPANY SECURITY INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SILVER INDUSTRIES, INC., A CORP. OF CT.
Assigned to SILVER INDUSTRIES, INC. reassignment SILVER INDUSTRIES, INC. LICENSE (SEE DOCUMENT FOR DETAILS). Assignors: HARTFORD NATIONAL BANK AND TRUT COMPANY (A NATIONAL BANKING ASSOCIATION)
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/286—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
    • A61M2005/287—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst by displacing occluding plugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/286—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst

Definitions

  • a plunger is depressed into the barrel causing the material in the compartment above the separator to act against the separator causing it to be cammed out of a transverse position in the barrel so that the material in the first compartment may flow into the second compartment mixing with the material therein.
  • a continued stroke of the plunger causes the separator to travel with the plunger against the mixed material forcing it out through an opening in the bottom of the barrel and then into a needle.
  • the present invention relates to an improved syringe of the type having two compartments. More particularly, the invention relates to disposable hypodermic syringes where two materials are stored in separate compartments until shortly before they are desired to be used as a mixture and ejected from the syringe.
  • hypodermic syringes The use of two compartment hypodermic syringes is well established. In many cases it is desired to keep a powdered pharmaceutical or medicament in one compartment of a syringe but sealed off from a diluent or solvent stored in another compartment. Prior to use, the dilutent or solvent is forced through some sealing means into the compartment containing the pharmaceutical or medicament. There they are mixed together and then the mixed material is forced out through a hypodermic needle, canula or opening.
  • FIGURE 1 is an exploded side view showing the various components of the present invention
  • FIGURE 2 is a sectional side view of the two compartments of the present invention.
  • FIGURE 3 is similar to FIGURE 2 but with the plunger partially depressed to cam the separator to slightly tilted position permitting material to pass from one compartment to the other;
  • FIGURE 4 is similar to FIGURE 2 but with the plunger contacting the separator and moved past the support;
  • FIGURE 5 is similar to FIGURE 2 with the plunger and the separator adjacent to each other and moved to the bottom of the barrel of the syringe;
  • FIGURE 6 is a plan section through the barrel of FIGURE 2 showing the support in relation to the side wall.
  • a syringe 10 in accordance with the present invention is shown as an exploded assembly of several components.
  • the syringe is comprised of a barrel portion 12 into which is fitted a plunger 14.
  • a compartment separator 16 is positioned transversely within the barrel 12 and rests on a support member 18.
  • a needle 20 is attached to the barrel 12 and may be protected if desired by a needle cap 22. It is understood that a canula or any opening may be used.
  • the barrel 12 is generally of cylindrical shape comprised of a side wall 24 and a bottom wall 26.
  • An opening 28 is provided in the bottom wall 26 and this opening communicates with the needle 20.
  • the separator 16 divides the barrel 12 into a lower compartment 30 and an upper compartment 32.
  • a first material in the form of a solvent or dilutent in the illustrated embodiment
  • a second material in the illustrated embodiment in the form of a powder
  • the separator 16 is in liquid type contact with the side wall 24 and therefore the materials in the upper and lower compartments 30 and 32 are kept separated from each other.
  • a seal plate 38 is provided on the stem 40 of the plunger 14.
  • a thumb piece 42 is provided on the upper end of the plunger, and a finger flange 44 is provided on the barrel 12 to provide finger grips for the user.
  • the separator 16 rests on a support in the form of the abutment 18, the abutment being only a few mils thick.
  • the extent and size of the abutment 18 will depend upon several factors, including the diameter of the barrel, the types of materials involved and so forth. In actual practice, an abutment of at least five mils has been found to be desirable.
  • the plunger In order to move material from the upper compartment 32 into the lower compartment 30, the plunger is forced downwardly into the barrel in a piston-like action.
  • the seal plate 38 is maintained in liquid tight engagement with the side wall of the barrel and forces the material in the upper compartment 32 against the separator 16.
  • the pressure on the separator 16 is such that the abutment 18 adds support to the area 46 of the separator in contact with it acting as a cam.
  • the remainder of the separator is not so supported and since the edge 48 of the separator 16 away from the abutment 18 is unsupported, the pressure exerted by the seal plate 38 causes that edge 48 to be forced downwardly.
  • As it is forced downwardly it forms a passage way between the side wall and the edge permitting any material in the upper compartment 32 to pass into the lower compartment 30.
  • the camming of the separator is particularly shown in FIGURE 3.
  • the barrel, plunger and separator may be readily molded from material such as polyethylene or polypropylene.
  • the only requirement is that the material used for the separator and the seal plate on the plunger be preferably and advantageously self-lubricating to permit them to move slidably through the barrel along the side wall without the need of additional lubrication.
  • the needle 20, if it is to be used to make an injection through the skin of a body of a human or an animal of course must be of a metallic nature such as a hollow steel needle.
  • it if it is to be inserted into an opening such as the canal in the teat of a cow, it can be of a plastic material and molded integrally with the lower barrel 12.
  • An improved two compartment syringe of the type adapted to be used with a hollow member comprising:
  • a barrel having side and bottom walls and an open end opposite said bottom wall, an opening in the bottom wall adapted to be connected to the member or other P a plunger having a seal plate and positioned within the side wall of the barrel in slidable but liquid-tight relationship therewith,
  • a separator positioned transversely across the barrel and adjacent to the cam, said separator being in liquid-tight relationship with the side wall of the barrel and positioned between the cam and the seal plate on the plunger,
  • separator dividing sa-id barrel into two compartments whereby two separate materials may be stored in each compartment and mixed together by forcing the seal plate towards the separator so that the material in the compartment adjacent to the seal plate forces the separator against the cam causing it to be forced out of liquid-tight relationship with the side wall of the barrel permitting the two separate materials to be mixed together.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
US807690A 1969-03-17 1969-03-17 Two compartment syringe with a single barrel Expired - Lifetime US3494359A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80769069A 1969-03-17 1969-03-17

Publications (1)

Publication Number Publication Date
US3494359A true US3494359A (en) 1970-02-10

Family

ID=25196959

Family Applications (1)

Application Number Title Priority Date Filing Date
US807690A Expired - Lifetime US3494359A (en) 1969-03-17 1969-03-17 Two compartment syringe with a single barrel

Country Status (8)

Country Link
US (1) US3494359A (de)
JP (1) JPS504992B1 (de)
BE (1) BE747421A (de)
CH (1) CH505625A (de)
DE (1) DE2012607C3 (de)
FR (1) FR2037959A5 (de)
GB (1) GB1300163A (de)
SE (1) SE358557B (de)

Cited By (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3563415A (en) * 1969-06-04 1971-02-16 Multi Drop Adapter Corp Multidrop adapter
US3595439A (en) * 1969-09-09 1971-07-27 Minnesota Mining & Mfg Combination mixing capsule and dispenser
US3662753A (en) * 1970-05-25 1972-05-16 Kitchener B Tassell Syringe
US3739947A (en) * 1969-08-01 1973-06-19 E Baumann Storing and mixing receptacle
US3858580A (en) * 1969-06-04 1975-01-07 Ims Ltd Intravenous container mixing assembly
US4128136A (en) * 1977-12-09 1978-12-05 Lamage Limited Drill bit
US4172457A (en) * 1977-10-06 1979-10-30 American Hospital Supply Corporation Plural component mixing system and method
US4208133A (en) * 1978-01-07 1980-06-17 Korte-Jungermann Gesellschaft fur Fassadenbau und Befesstigungstechnik mit beschrankter Haftung Injection cartridge
US4366919A (en) * 1978-05-01 1983-01-04 Coaxial Cartridges, Inc. Composite cartridge and device for metering extrusion of contents
US4394863A (en) * 1981-10-23 1983-07-26 Survival Technology, Inc. Automatic injector with cartridge having separate sequentially injectable medicaments
US4463875A (en) * 1982-06-14 1984-08-07 Robert W. Mann Method and apparatus for preparing and applying a two-component cement
US4689042A (en) * 1985-05-20 1987-08-25 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
DE3618318A1 (de) * 1986-05-30 1987-12-03 Rau Roland Injektionsspritze
WO1991000094A1 (en) * 1989-06-28 1991-01-10 Finn Tranberg A new papaverine injection system
US4994043A (en) * 1987-06-16 1991-02-19 Akzo N.V. Two compartment syringe
US5137528A (en) * 1990-11-26 1992-08-11 Crose Virginia W Ampoule for administering a liquid local anaesthetic
US5301842A (en) * 1991-03-06 1994-04-12 Frank Ritter Multicomponent cartridge for plastic materials
US5472422A (en) * 1992-07-07 1995-12-05 Pharmacia Aktiebolag Dual-chamber injection cartridge
US5522804A (en) * 1994-02-15 1996-06-04 Lynn; Lawrence A. Aspiration, mixing, and injection syringe
DE29605790U1 (de) * 1996-03-28 1996-08-08 Dr. Karl Thomae Gmbh, 88400 Biberach Spritze für medizinische Zwecke
US5662472A (en) * 1995-08-18 1997-09-02 Dentsply Gmbh Hue and lightness identification system for dental products
US5817055A (en) * 1992-07-07 1998-10-06 Pharmacia & Upjohn Aktiebolag Dual-chamber injection cartridge
US20040079363A1 (en) * 2001-01-12 2004-04-29 Casper Robert A. Medicament respiratory delivery device and method
US20050000514A1 (en) * 2001-01-12 2005-01-06 Becton, Dickinson And Company Medicament microdevice delivery system, cartridge and method of use
US20050113768A1 (en) * 2003-11-24 2005-05-26 Carlos Patrickson Pain-alleviating injection needle
US20080091148A1 (en) * 2006-10-17 2008-04-17 Arte Corporation Combined container-syringe
US20080215012A1 (en) * 2005-02-02 2008-09-04 Taisei Kakoco., Ltd. Syringe
US20080230565A1 (en) * 2005-10-14 2008-09-25 Arno Hohmann Plunger and Plunger Assembly For a Cartridge, System For Storing a Substance, and Method of Filling and Sealing a Substance in a Delivery System
US20100249829A1 (en) * 2009-03-30 2010-09-30 Derek Rissman Compartmented Syringe
US8057090B1 (en) * 2005-08-31 2011-11-15 Subrata Saha Automated bone cement mixer
US8865857B2 (en) 2010-07-01 2014-10-21 Sofradim Production Medical device with predefined activated cellular integration
US9247931B2 (en) 2010-06-29 2016-02-02 Covidien Lp Microwave-powered reactor and method for in situ forming implants
US9510810B2 (en) 2009-02-21 2016-12-06 Sofradim Production Medical devices incorporating functional adhesives
US9775928B2 (en) 2013-06-18 2017-10-03 Covidien Lp Adhesive barbed filament
US10259635B2 (en) 2014-11-28 2019-04-16 Sulzer Mixpac Ag Apparatus and methods for storing and mixing separate substances
US11185391B2 (en) 2016-09-21 2021-11-30 3M Innovative Properties Company Mixer assembly and device for dispensing a dental material

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018222A (en) * 1975-02-10 1977-04-19 Merck & Co., Inc. Syringe containing frozen vaccine
DE7916475U1 (de) * 1979-06-08 1979-10-18 Hoechst Ag, 6000 Frankfurt Spriihapplikator
FR2539302B1 (fr) * 1983-01-17 1986-03-14 Brunet Jean Louis Seringue a usage medical
SE464963B (sv) * 1988-12-14 1991-07-08 Gudmar Olovson Injektionsspruta
WO2000062828A1 (en) 1996-04-30 2000-10-26 Medtronic, Inc. Autologous fibrin sealant and method for making the same
DE602004001126T2 (de) * 2004-03-11 2007-06-06 3M Espe Ag Kapsel zur Lagerung, Mischung und Ausgabe von Materialien
WO2016120333A1 (en) 2015-01-28 2016-08-04 Cube Pharmaceuticals N.Kalofolias & Co. Oe Devices and methods for establishing communication between chambers in a multi-chambered vessel

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1929616A (en) * 1932-04-29 1933-10-10 William O Vopata Double compartment ampule
US2390246A (en) * 1940-10-18 1945-12-04 Marvin L Folkman Syringe
US2549417A (en) * 1949-08-10 1951-04-17 Frederick M Turnbull Syringe ampoule
US3052239A (en) * 1959-01-29 1962-09-04 Silver Disposable hypodermic syringe
US3052240A (en) * 1959-01-29 1962-09-04 Silver Disposable hypodermic syringe
US3380451A (en) * 1965-06-14 1968-04-30 Robert E. Porter Two compartment syringe

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1929616A (en) * 1932-04-29 1933-10-10 William O Vopata Double compartment ampule
US2390246A (en) * 1940-10-18 1945-12-04 Marvin L Folkman Syringe
US2549417A (en) * 1949-08-10 1951-04-17 Frederick M Turnbull Syringe ampoule
US3052239A (en) * 1959-01-29 1962-09-04 Silver Disposable hypodermic syringe
US3052240A (en) * 1959-01-29 1962-09-04 Silver Disposable hypodermic syringe
US3380451A (en) * 1965-06-14 1968-04-30 Robert E. Porter Two compartment syringe

Cited By (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3563415A (en) * 1969-06-04 1971-02-16 Multi Drop Adapter Corp Multidrop adapter
US3858580A (en) * 1969-06-04 1975-01-07 Ims Ltd Intravenous container mixing assembly
US3739947A (en) * 1969-08-01 1973-06-19 E Baumann Storing and mixing receptacle
US3595439A (en) * 1969-09-09 1971-07-27 Minnesota Mining & Mfg Combination mixing capsule and dispenser
US3662753A (en) * 1970-05-25 1972-05-16 Kitchener B Tassell Syringe
USRE29062E (en) * 1972-11-01 1976-12-07 Ims Limited Intravenous container mixing assembly
US4243080A (en) * 1977-10-06 1981-01-06 American Hospital Supply Corporation Method of mixing plural components
US4172457A (en) * 1977-10-06 1979-10-30 American Hospital Supply Corporation Plural component mixing system and method
US4128136A (en) * 1977-12-09 1978-12-05 Lamage Limited Drill bit
US4208133A (en) * 1978-01-07 1980-06-17 Korte-Jungermann Gesellschaft fur Fassadenbau und Befesstigungstechnik mit beschrankter Haftung Injection cartridge
US4366919A (en) * 1978-05-01 1983-01-04 Coaxial Cartridges, Inc. Composite cartridge and device for metering extrusion of contents
US4394863A (en) * 1981-10-23 1983-07-26 Survival Technology, Inc. Automatic injector with cartridge having separate sequentially injectable medicaments
US4463875A (en) * 1982-06-14 1984-08-07 Robert W. Mann Method and apparatus for preparing and applying a two-component cement
US4755169A (en) * 1985-05-20 1988-07-05 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
US4689042A (en) * 1985-05-20 1987-08-25 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
DE3618318A1 (de) * 1986-05-30 1987-12-03 Rau Roland Injektionsspritze
US4994043A (en) * 1987-06-16 1991-02-19 Akzo N.V. Two compartment syringe
WO1991000094A1 (en) * 1989-06-28 1991-01-10 Finn Tranberg A new papaverine injection system
US5137528A (en) * 1990-11-26 1992-08-11 Crose Virginia W Ampoule for administering a liquid local anaesthetic
US5301842A (en) * 1991-03-06 1994-04-12 Frank Ritter Multicomponent cartridge for plastic materials
US5472422A (en) * 1992-07-07 1995-12-05 Pharmacia Aktiebolag Dual-chamber injection cartridge
US5817055A (en) * 1992-07-07 1998-10-06 Pharmacia & Upjohn Aktiebolag Dual-chamber injection cartridge
US6228065B1 (en) 1994-02-15 2001-05-08 Lawrence A. Lynn Displacement activated medical check valve
US5549569A (en) * 1994-02-15 1996-08-27 Lawrence A. Lynn Ex vivo blood isolation system
US5643218A (en) * 1994-02-15 1997-07-01 Lawrence A. Lynn Auto-flushing medical fluid injection system
US5769825A (en) * 1994-02-15 1998-06-23 Lynn; Lawrence A. Self-contained syringe and pharmaceutical packaging system for enclosed mixing of pharmaceutical and diluent
US5522804A (en) * 1994-02-15 1996-06-04 Lynn; Lawrence A. Aspiration, mixing, and injection syringe
US5697915A (en) * 1994-02-15 1997-12-16 Lynn; Lawrence A. Displacement-activated medical check valve
US5743886A (en) * 1994-02-15 1998-04-28 Lawrence A. Lynn Sequential medical fluid aspiration and injection system and method
US5662472A (en) * 1995-08-18 1997-09-02 Dentsply Gmbh Hue and lightness identification system for dental products
DE29605790U1 (de) * 1996-03-28 1996-08-08 Dr. Karl Thomae Gmbh, 88400 Biberach Spritze für medizinische Zwecke
WO1997036624A1 (de) * 1996-03-28 1997-10-09 Dr. Karl Thomae Gmbh Spritze für medizinische zwecke
US7850663B2 (en) 2001-01-12 2010-12-14 Becton, Dickinson And Company Medicament microdevice delivery system, cartridge and method of use
US20040079363A1 (en) * 2001-01-12 2004-04-29 Casper Robert A. Medicament respiratory delivery device and method
US20050000514A1 (en) * 2001-01-12 2005-01-06 Becton, Dickinson And Company Medicament microdevice delivery system, cartridge and method of use
US7051734B2 (en) 2001-01-12 2006-05-30 Becton Dickinson And Company Medicament respiratory delivery device and method
US8251958B2 (en) 2001-01-12 2012-08-28 Becton, Dickinson And Company Medicament microdevice delivery system, cartridge and method of use
US20050113768A1 (en) * 2003-11-24 2005-05-26 Carlos Patrickson Pain-alleviating injection needle
US20080215012A1 (en) * 2005-02-02 2008-09-04 Taisei Kakoco., Ltd. Syringe
US7935078B2 (en) * 2005-02-02 2011-05-03 Taisei Kako Co., Ltd. Multi-chambered syringe
US8057090B1 (en) * 2005-08-31 2011-11-15 Subrata Saha Automated bone cement mixer
US8382363B1 (en) * 2005-08-31 2013-02-26 Subrata Saha Automated bone cement mixer
US10279935B2 (en) * 2005-10-14 2019-05-07 3M Innovative Properties Company Plunger and plunger assembly for a cartridge, system for storing a substance, and method of filing and sealing a substance in a delivery system
US20170197740A1 (en) * 2005-10-14 2017-07-13 3M Innovative Properties Company Plunger and plunger assembly for a cartridge, system for storing a substance, and method of filing and sealing a substance in a delivery system
US20080230565A1 (en) * 2005-10-14 2008-09-25 Arno Hohmann Plunger and Plunger Assembly For a Cartridge, System For Storing a Substance, and Method of Filling and Sealing a Substance in a Delivery System
US9844796B2 (en) * 2005-10-14 2017-12-19 3M Innovative Properties Company Plunger and plunger assembly for a cartridge, system for storing a substance, and method of filling and sealing a substance in a delivery system
US20080091148A1 (en) * 2006-10-17 2008-04-17 Arte Corporation Combined container-syringe
US9510810B2 (en) 2009-02-21 2016-12-06 Sofradim Production Medical devices incorporating functional adhesives
US8376989B2 (en) 2009-03-30 2013-02-19 Covidien Lp Compartmented syringe
US20100249829A1 (en) * 2009-03-30 2010-09-30 Derek Rissman Compartmented Syringe
US9247931B2 (en) 2010-06-29 2016-02-02 Covidien Lp Microwave-powered reactor and method for in situ forming implants
US8865857B2 (en) 2010-07-01 2014-10-21 Sofradim Production Medical device with predefined activated cellular integration
US9775928B2 (en) 2013-06-18 2017-10-03 Covidien Lp Adhesive barbed filament
US10259635B2 (en) 2014-11-28 2019-04-16 Sulzer Mixpac Ag Apparatus and methods for storing and mixing separate substances
US11185391B2 (en) 2016-09-21 2021-11-30 3M Innovative Properties Company Mixer assembly and device for dispensing a dental material

Also Published As

Publication number Publication date
SE358557B (de) 1973-08-06
JPS504992B1 (de) 1975-02-26
DE2012607C3 (de) 1980-01-24
DE2012607B2 (de) 1979-05-23
BE747421A (fr) 1970-08-31
FR2037959A5 (de) 1970-12-31
GB1300163A (en) 1972-12-20
DE2012607A1 (de) 1970-10-01
CH505625A (de) 1971-04-15

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Legal Events

Date Code Title Description
AS Assignment

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