US3306563A - Aseptic draining and support means for flexible bags - Google Patents

Aseptic draining and support means for flexible bags Download PDF

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Publication number
US3306563A
US3306563A US38672464A US3306563A US 3306563 A US3306563 A US 3306563A US 38672464 A US38672464 A US 38672464A US 3306563 A US3306563 A US 3306563A
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Prior art keywords
patch
aseptic
draining
cannula
seen
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Soto Ricardo Hurtado
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Soto Ricardo Hurtado
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089Containers or vials which are to be joined to each other in order to mix their contents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096Combination of a vial and a syringe for transferring or mixing their contents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10Bag-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/1475Inlet or outlet ports
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006Piercing means
    • A61J1/201Piercing means having one piercing end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006Piercing means
    • A61J1/2013Piercing means having two piercing ends
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10Methods of surface bonding and/or assembly therefor

Description

Feb. 28, 1967 R H, SOTO 3,306,563

ASEPTIC DRAINING AND SUPPORT MEANS FOR FLEXIBLE BAGS Filed July 31, 1964 FIGB n9 WIIIIIIIIIIII, l

INVENTOR; RICARDO H. SOTO BY c jaw wm a W2 ATT' YS United States Patent 0.

3,306,563 ASEPTIC DRAINING AND SUPPORT MEANS FOR FLEXIBLE BAGS Ricardo Hurtado Soto, Aptdo. Aereo 9263, Bogota, Colombia Filed July 31, 1964, Ser. No. 386,724 1 Claim. (Cl. 248224) This invention relates to aseptic draining means for flexible bags and, more particularly, to a novel patch adapted to be adhesively united to a flexible container and which is capable of rescaling following cannula puncture.

It is an object of the invention to provide a novel method and means for draining flexible containers, particularly through the use of readily afiixed cannulae. As such, the invention has particular utility in conjunction with the dispensing and administration of liquid medic- Another object of the invention is to provide a novelly contoured or constructed patch adapted to be adhesively united to a flexible container, i.e., a plastic bag, in which the patch construction facilitates coupling of the bag to another element.

Other objects and advantages of the invention may be seen in the details of construction and operation set down in this specification.

The invention is described in conjunction with the accompanying drawing, in which FIG. 1 is an elevational view of an embodiment of the invention wherein a powdered medicament container is coupled to a liquid container through the guise of a double ended cannula piercing patches constructed according to the instant invention;

FIG. 2 is an enlarged fragmentary sectional view of the central portion of FIG. 1 and whereby additional details of construction can be seen;

FIG. 3 is a perspective view of the double ended cannula of the preceding views;

FIG. 4 is a fragmentary sectional view of a modified form of the invention;

FIG. 5 is an elevational view of yet another form of the invention;

FIG. 6 is an elevational view showing a liquid container coupled to a hypodermic syringe, the syringe being shown fragmentarily;

FIG. 7 is a perspective view of one form of the inventive patch;

FIG. 8 is an enlarged sectional view of the patch of FIG. 7, with protective strips removed;

FIG. 9 is a perspective view of another form of the inventive patch; and

FIG. 10 is a sectional view of the patch of FIG. 9 with protective strips removed.

Referring now to FIG. 1, represented is the operation of transferring a liquid such as 'water from an upper bag or container 10 to a lower bag or container 13 by means of a double ended cannula 12 piercing patches 11 and 11. The lower bag 13 may contain a powder suitable for solution just prior to administration or other use.

The particular patch employed in the embodiment seen in FIG. 1 can be appreciated from a consideration of FIGS. 2 and 9. Referring first to FIG. 9 it is seen that the numeral 11 again generally designates the patch which is initially covered by means of protector strips 14 and 15 seen in the process of being removed from the upper surface of the patch. Similarly, a bottom protector 16 is seen in the process of being removed. The patch 11 is equipped with a central recess 17 and disposed within the central recess 17 is a smaller opening 18. The upper surface of the patch 11 is covered by an adhesive layer 19 3,306,563 Patented Feb. 28, 1967 while the lower surface is covered by an adhesive layer 20.

The assembly of FIG. 2 is achieved when the double ended cannula 12 is employed and the cannula 12 is seen in perspective in FIG. 3. There it will be noted that the through bore 12a communicates with the beveled or pointed end 12b so as to provide a flow passage for liquid from the container 10 to the container 13. Additionally, the chamber formed by the recesses 17 and 17 (see FIG. 2) accommodates the manipulating portion 12c of the cannula 12. The chamber formed by the recesses 17 and 17' is created by joining two patches as shown in FIG. 10 by means of the adhesive layers 20 of the two patches. The joined adhesive layers of the two patches become the layer 21 of the double patch shown in FIG. 2.

In the operation depicted in FIG. 1, the protectors 14- 16 have been removed and the patch 11 resulting therefrom has been applied along an edge of the plastic bag 10 which may be constructed of polyvinyl chloride, polyethylene, etc. Such materials are transparent preferably and are incapable of confining the puncture made by a cannula of the size normally employed for transferring fluid. With the inventive patch however a tight aseptic seal with the cannula 12 is achieved. Further, the patch 11 in extending along both the front and back faces of the bag 10 serves to confine portions of the bag against any tendency to rupture under the penetration of the cannula Another environment in which the invention is advantageously used can be seen in FIG. 5 where a container of medicament, paste, etc. is designated by the numeral and has adhesively afiixed thereto the inventive patch 111 and also features the attachment of a delivery cannula 112. The particular patch employed in the FIG. 5 showing can be seen in FIGS. 7 and 8. In FIG. 7 the numeral 111 again designates generally the patch which is seen to include protectors 114, and 11-6 with the protectors 114 and 115 being partially removed to expose the adhesive layer of 119. In the embodiment of the invention used in FIG. 5 there is no need for having a second adhesive layer (corresponding to the layer 20 of FIG. 10) inasmuch as the l-owersurface of the patch 111 is exposed to the atmosphere as can be appreciated from a consideration of FIG. 5.

Yet another environment in which the invention finds advantageous application is seen in FIG. 6 wherein a medicament container 210 is again equipped with an edge-overlapping patch 211 for penetration by means of a cannula 212 provided as part of a hypodermic syringe barrel generally designated 213. In this fashion, liquid medicament can be withdrawn sequentially and intermittently from the container 210 without a possibility of contamination inasmuch as the rubber patch reseals itself upon cannula removal. The aseptic character of the patch is advantageously obtained by adding to the rubber an atoxic antiseptic substance such as zinc 2-pyridinethiol 10xide. Relative to the adhesive, a variety of adhesives are commercially available which are pressure sensitive and adapted to adhere rubber to plastic materials.

A further modification of the patch can take the form seen in FIG. 4, the adhesive strap or patch generally designated 311 is seen to be equipped with a projecting part for coupling to a box or other support surface as at 322. The strap 311 is seen to include a flange 323 which is tapered so as to facilitate insertion through the opening 322a in a rigid member such as the side of :a box or other enclosure. To facilitate entry of the cannula 312 into the container 310, the patch 311 is equipped with a transverse passage 317 which is closed at its outer end as at 317a by an integral portion of the patch 311.

While in the foregoing specification a detailed description of the invention has been set down for the purpose 3 of explanation, many variations of the details herein given may -be made by those skilled in the art without departing from the spirit and scope of the invention.

I claim:

A resilient, rubber-like patch'adapted for contact attachment to a liquid-filled, flexible container to be drained, said patch being adapted to reseal itself following cannula puncture and containing an antiseptic material dispersed therein, said patch including a lower planar portion having a layer of adhesive attached to the bottom surface thereof, said patch including an upper portion extending upwardly from said planar portion, said upper portion being generally cylindrical and having a vertically extending bore provided therein, said bore being closed at the top and bottom thereof, said upper portion including a radially outwardly extending flange, said flange having a generally fiat lower surface spaced from the upper surface of said lower planar portion and an inclined upper sur- 4 face, whereby said upper portion is adapted to be inserted through an opening in a rigid support for supporting said patch and container by said flange.

References Cited by the Examiner UNITED STATES PATENTS 2,237,218 4/1941 Flynn 128-349 2,704,075 3/ 1955 Cherkin 128-272 2,856,929 10/1958 Gossett et al 128-272 3,066,833 12/1962 Hershenson 222-81 3,126,004 3/1964 Sarnoff 128272 FOREIGN PATENTS 1,070,250 2/1954 France. 1,195,250 11/1959 France.

ROBERT B. REEVES, Primary Examiner. WALTER SOBIN, RAPHAEL M. LUPO, Examiners.

US38672464 1964-07-31 1964-07-31 Aseptic draining and support means for flexible bags Expired - Lifetime US3306563A (en)

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Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3480183A (en) * 1967-02-27 1969-11-25 Impact Container Corp Container outlet opening outfitted with one piece,double seal gasket
US3613663A (en) * 1968-09-09 1971-10-19 Roger P Johnson Apparatus to provide communication with the veins of a patient
US3902489A (en) * 1972-06-23 1975-09-02 Avon Medicals Couplings
US3909910A (en) * 1973-03-29 1975-10-07 Union Carbide Corp Method of joining the ends of two conduits together in a sterile manner
US4004586A (en) * 1975-03-12 1977-01-25 Baxter Travenol Laboratories, Inc. Method and apparatus for sealed, sterile connection
US4019512A (en) * 1975-12-04 1977-04-26 Tenczar Francis J Adhesively activated sterile connector
US4022205A (en) * 1973-11-05 1977-05-10 Tenczar Francis J Fluid connectors
US4030494A (en) * 1973-11-05 1977-06-21 Francis Tenczar Fluid connectors
US4149534A (en) * 1977-05-06 1979-04-17 Tenczar Francis J Sterile film connectors
US4343399A (en) * 1981-04-13 1982-08-10 Celtite, Inc. Two component device for use in anchor bolting and method of anchoring
US4364387A (en) * 1980-12-18 1982-12-21 Abbott Laboratories Connecting device for medical liquid containers
WO1983003587A1 (en) * 1982-04-06 1983-10-27 Baxter Travenol Lab Separated packaging and sterile processing for liquid-powder mixing
EP0097054A2 (en) * 1982-06-15 1983-12-28 Hantaaki Oy Injection port for plastic bags
US4540035A (en) * 1984-03-28 1985-09-10 Simon Roberts Tire repair patch
EP0161231A2 (en) * 1984-05-09 1985-11-13 Tetra Pak Processing Systems Aktiebolag A kit forming a sterile system
US4601704A (en) * 1983-10-27 1986-07-22 Abbott Laboratories Container mixing system with externally mounted drug container
US4606734A (en) * 1984-02-22 1986-08-19 Abbott Laboratories Container mixing system with externally mounted drug container
US4632673A (en) * 1983-06-15 1986-12-30 Hantaaki Oy Pierceable port for containers
US4698061A (en) * 1984-03-02 1987-10-06 Baxter Travenol Laboratories, Inc. Injection site package
US4781679A (en) * 1986-06-12 1988-11-01 Abbott Laboratories Container system with integral second substance storing and dispensing means
US4786279A (en) * 1986-07-31 1988-11-22 Abbott Laboratories Container for mixture of materials
US4808179A (en) * 1984-05-09 1989-02-28 Ab Akerlund & Rausing Container device and a method for manufacturing of the device
US5090596A (en) * 1991-09-09 1992-02-25 Knight Robert W Plastic perforative spout device
US5465768A (en) * 1994-03-01 1995-11-14 Deroos; Bradley G. Fluid transport container
US5637107A (en) * 1994-12-29 1997-06-10 Vaillancourt; Vincent L. Sterilized vial closure and a sterilized parenteral vial
US5782820A (en) * 1996-02-12 1998-07-21 Roland; Patricia D. Disposable seal for vacutainer holder
US20050054238A1 (en) * 1997-05-09 2005-03-10 Pall Corporation Connector assembly
EP2200559A1 (en) * 2007-09-17 2010-06-30 Carmel Pharma AB Bag connector
US8454059B2 (en) 2010-09-13 2013-06-04 Pall Corporation Connector assemblies, fluid systems including connector assemblies, and procedures for making fluid connections
US20130142992A1 (en) * 2011-12-02 2013-06-06 Claudio ROVELLI Fluid tight tape for cooking under vacuum

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2237218A (en) * 1938-09-29 1941-04-01 Wardlyn Corp Application of cellulose derivatives
FR1070250A (en) * 1953-02-02 1954-07-20 Method and apparatus for making injections
US2704075A (en) * 1952-03-10 1955-03-15 Baxter Don Inc Flexible plastic container
US2856929A (en) * 1954-07-22 1958-10-21 Baxter Don Inc Plastic container
FR1195250A (en) * 1956-11-27 1959-11-16 Improvements to means for facilitating the filling and sealing of individual thin walled containers
US3066833A (en) * 1960-05-25 1962-12-04 Baxter Don Inc Container with closure having a retractable spout
US3126004A (en) * 1964-03-24 Cartridge with antipilfering pistojf

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126004A (en) * 1964-03-24 Cartridge with antipilfering pistojf
US2237218A (en) * 1938-09-29 1941-04-01 Wardlyn Corp Application of cellulose derivatives
US2704075A (en) * 1952-03-10 1955-03-15 Baxter Don Inc Flexible plastic container
FR1070250A (en) * 1953-02-02 1954-07-20 Method and apparatus for making injections
US2856929A (en) * 1954-07-22 1958-10-21 Baxter Don Inc Plastic container
FR1195250A (en) * 1956-11-27 1959-11-16 Improvements to means for facilitating the filling and sealing of individual thin walled containers
US3066833A (en) * 1960-05-25 1962-12-04 Baxter Don Inc Container with closure having a retractable spout

Cited By (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3480183A (en) * 1967-02-27 1969-11-25 Impact Container Corp Container outlet opening outfitted with one piece,double seal gasket
US3613663A (en) * 1968-09-09 1971-10-19 Roger P Johnson Apparatus to provide communication with the veins of a patient
US3902489A (en) * 1972-06-23 1975-09-02 Avon Medicals Couplings
US3909910A (en) * 1973-03-29 1975-10-07 Union Carbide Corp Method of joining the ends of two conduits together in a sterile manner
US4022205A (en) * 1973-11-05 1977-05-10 Tenczar Francis J Fluid connectors
US4030494A (en) * 1973-11-05 1977-06-21 Francis Tenczar Fluid connectors
US4004586A (en) * 1975-03-12 1977-01-25 Baxter Travenol Laboratories, Inc. Method and apparatus for sealed, sterile connection
US4019512A (en) * 1975-12-04 1977-04-26 Tenczar Francis J Adhesively activated sterile connector
US4149534A (en) * 1977-05-06 1979-04-17 Tenczar Francis J Sterile film connectors
US4364387A (en) * 1980-12-18 1982-12-21 Abbott Laboratories Connecting device for medical liquid containers
US4343399A (en) * 1981-04-13 1982-08-10 Celtite, Inc. Two component device for use in anchor bolting and method of anchoring
WO1983003587A1 (en) * 1982-04-06 1983-10-27 Baxter Travenol Lab Separated packaging and sterile processing for liquid-powder mixing
EP0097054A2 (en) * 1982-06-15 1983-12-28 Hantaaki Oy Injection port for plastic bags
EP0097054A3 (en) * 1982-06-15 1984-12-12 Hantaaki Oy Injection port for plastic bags
US4632673A (en) * 1983-06-15 1986-12-30 Hantaaki Oy Pierceable port for containers
US4601704A (en) * 1983-10-27 1986-07-22 Abbott Laboratories Container mixing system with externally mounted drug container
US4606734A (en) * 1984-02-22 1986-08-19 Abbott Laboratories Container mixing system with externally mounted drug container
US4698061A (en) * 1984-03-02 1987-10-06 Baxter Travenol Laboratories, Inc. Injection site package
US4540035A (en) * 1984-03-28 1985-09-10 Simon Roberts Tire repair patch
EP0161231A3 (en) * 1984-05-09 1986-03-19 Ab Akerlund & Rausing A container device and a method for manufacturing of the device
EP0161231A2 (en) * 1984-05-09 1985-11-13 Tetra Pak Processing Systems Aktiebolag A kit forming a sterile system
US4808179A (en) * 1984-05-09 1989-02-28 Ab Akerlund & Rausing Container device and a method for manufacturing of the device
US4781679A (en) * 1986-06-12 1988-11-01 Abbott Laboratories Container system with integral second substance storing and dispensing means
US4786279A (en) * 1986-07-31 1988-11-22 Abbott Laboratories Container for mixture of materials
US5090596A (en) * 1991-09-09 1992-02-25 Knight Robert W Plastic perforative spout device
US5465768A (en) * 1994-03-01 1995-11-14 Deroos; Bradley G. Fluid transport container
US5637107A (en) * 1994-12-29 1997-06-10 Vaillancourt; Vincent L. Sterilized vial closure and a sterilized parenteral vial
US5782820A (en) * 1996-02-12 1998-07-21 Roland; Patricia D. Disposable seal for vacutainer holder
US20050054238A1 (en) * 1997-05-09 2005-03-10 Pall Corporation Connector assembly
US7090191B2 (en) * 1997-05-09 2006-08-15 Pall Corporation Connector assembly
EP2200559A1 (en) * 2007-09-17 2010-06-30 Carmel Pharma AB Bag connector
US20100249745A1 (en) * 2007-09-17 2010-09-30 Carmel Pharma Ab Bag connector
EP2200559A4 (en) * 2007-09-17 2013-12-25 Carmel Pharma Ab Bag connector
US8827978B2 (en) 2007-09-17 2014-09-09 Carmel Pharma Ab Bag connector
US8454059B2 (en) 2010-09-13 2013-06-04 Pall Corporation Connector assemblies, fluid systems including connector assemblies, and procedures for making fluid connections
US20130142992A1 (en) * 2011-12-02 2013-06-06 Claudio ROVELLI Fluid tight tape for cooking under vacuum
US9012004B2 (en) * 2011-12-02 2015-04-21 Plastar Pak S.R.L. Fluid tight tape for cooking under vacuum

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