US3071316A - Bottle support and cap assembly for centrifuge - Google Patents

Bottle support and cap assembly for centrifuge Download PDF

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Publication number
US3071316A
US3071316A US814305A US81430559A US3071316A US 3071316 A US3071316 A US 3071316A US 814305 A US814305 A US 814305A US 81430559 A US81430559 A US 81430559A US 3071316 A US3071316 A US 3071316A
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United States
Prior art keywords
bottle
cap assembly
rotor
centrifuge
neck
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US814305A
Inventor
Piemonte William John
Alexander F Ippolito
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Lourdes Instrument Corp
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Lourdes Instrument Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Lourdes Instrument Corp filed Critical Lourdes Instrument Corp
Priority to US814305A priority Critical patent/US3071316A/en
Priority claimed from US854281A external-priority patent/US3050239A/en
Application granted granted Critical
Publication of US3071316A publication Critical patent/US3071316A/en
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Expired - Lifetime legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021Test tubes specially adapted for centrifugation purposes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/54Labware with identification means
    • B01L3/545Labware with identification means for laboratory containers
    • B01L3/5453Labware with identification means for laboratory containers for test tubes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0414Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0414Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes
    • B04B5/0421Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes pivotably mounted
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B9/00Drives specially designed for centrifuges; Arrangement or disposition of transmission gearing; Suspending or balancing rotary bowls
    • B04B9/10Control of the drive; Speed regulating
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/07Centrifugal type cuvettes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B7/00Elements of centrifuges
    • B04B7/02Casings; Lids
    • B04B2007/025Lids for laboratory centrifuge rotors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0401Sample carriers, cuvettes or reaction vessels
    • G01N2035/0429Sample carriers adapted for special purposes
    • G01N2035/0436Sample carriers adapted for special purposes with pre-packaged reagents, i.e. test-packs

Definitions

  • This invention relates to bottle supports and more fspecifically to a support in combination With a sealing cap assembly for 4a bottle, as mounted in an angle type centrifuge.
  • lt is a further object of this invention to provide a reinforcing supporting assembly for the cap mounted in a fragile bottle that is to be utilized in the rotor of an angle type centrifuge.
  • FIG. l is a cross sectional view of a centrifuge rotor, in which a plurality of bottles are mounted in spaced relation in pockets within the rotor, and
  • FIG. 2 is a cross sectional View of the bottle and supporting cap assembly.
  • an angle -type centrifuge rotor that is provided with a plurality of pockets 12 (six compartments or pockets in this instance) in which bottles 15 (of approximately 250 ml. or 500 ml.) are mounted. These bottles are at approximately a 28 angle to the vertic-al axis.
  • the cap assembly is comprised of a stainless steel circular crown member 18 that covers and rests upon the top aperture or mouth of bottle 15.
  • the crown member 18 is provided with a central aperture 19 and on the inner surface of the crown member there is a reduced portion 20 which provides a shoulder 21.
  • a similar type element 22 of a smaller diameter is provided to be inserted within the mouth of said bottle 15, element 22 is similarly provided with a reduced portion 23 an-d a shoulder 24.
  • Element 22 is not provided with a central aperture, but rather is provided with an extended threaded stud 25.
  • a neoprene gasket v26 of a -fairly good thickness is inserted between elements 18 and 22, and with the stud 25 passing upward through the aperture 19 a nut 27 may be threadably secured to the stud 25 to retain the crown element 18 in juxtaposition to the gasket 26.
  • This assembly may be inserted in the mouth of the bottle 15 and by turning nut 27 to draw element 22 toward element l, there will be a squeezing and distor-tion of the gasket 26 to thus provide a tight sealing cap assembly 16. With bottle 15 properly sealed with the cap assembly 16, the bottle 15 may be mounted in a pocket 12 of the rotor.
  • a supporting element 17 is mounted to surround the neck of the bottle.
  • Supporting element 17 may be comprised of any rigid reinforcing material, such as aluminum, to provide the necessary strength.
  • Element 17 at its base 29 is formed or cut on its inner periphery to fit the contour of the curved upper portion 15A of bottle 15, and the base portion 29, on its periphery, is circular in form, With a diameter to match the diameter of the rotor compartment 12.
  • Element 17 may be formed on its inner periphery of the upper portion 30 -with a mating contour to mate with and match the outer periphery of the neck of bottle 15.
  • the upper end of portion 30 is also provided with a cut out portion 31 to permit the crown member 1S to fit into portion 31 of element 17.
  • the base portion 29 of the suppor-ting element 17 fits well within the bore of pocket 12 to provide a good solid support when the bottle 15 is mounted within pocket 12. The rest of the bottle is fully supported within the pocket of the rotor. It is apparent that when the rotor 10 is operated anda considerable centrifugal force is developed, this supporting element and cap assembly provides a rigid support for the polyethylene bottle 15 that is being utilized. With this supporting assembly, it is possible to -use a fairly light polyethylene bottle without danger of rupturing the bottle or losing the cap from the bot-tle due to any distortion.

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Centrifugal Separators (AREA)

Description

Jan. 1, 1963 W. J. PIEMONTE ETAL 3,071,316 BOTTLE SUPPORT AND CAP ASSEMBLY F' OR CENTRIF'UGE Filed May 19, 1959 INVENTORS wu/4M nu/,v Plinn/vrs ALEXANDER F. /PaL/ra United States Patent fltlce Patented Jan. 1, 1963 3,071,316 BOTTLE SUPPORT AND CAP ASSEMBLY FOR CENTRIFUGE William John Piemonte and Alexander F. Ippolito, Brooklyn, N.Y., assignors, by mesne assignments, to Lourdes Instrument Corporation, Brooklyn, N.Y.
Filed May 19, 1959, Ser. No. $14,305 1 Claim. (Cl. 233-26) This invention relates to bottle supports and more fspecifically to a support in combination With a sealing cap assembly for 4a bottle, as mounted in an angle type centrifuge.
The prior art relating to the support of a fragile bottle with a cap assembly is apparently only found in the type of mounting used for a vacuum bottle, in which the inner bottle is securely retained between the outer shell, a Vacuum about the inner bottle and a cap assembly to retain the inner bottle so that it will not be displaced or break. In utilizing a bottle, whether capped or uncapped, in an angle type centrifuge, because of the angle of the rotor compartments and the high speeds and the resultant centrifugal forces involved, all of the presently available plastic bottles have inadequate strength to withstand the centrifugal force when they are filled and capped. Further, the presently available sealing caps do not offer effective sealing during centrifugation.
It is an object of this invention to provide a cap aS- sembly for a fragile bottle, as mounted in the rotor of an -angle type centrifuge.
lt is a further object of this invention to provide a reinforcing supporting assembly for the cap mounted in a fragile bottle that is to be utilized in the rotor of an angle type centrifuge.
Further objects of this invention shall be apparent by reference to the accompanying detailed description and the drawings, in which:
FIG. l is a cross sectional view of a centrifuge rotor, in which a plurality of bottles are mounted in spaced relation in pockets within the rotor, and
FIG. 2 is a cross sectional View of the bottle and supporting cap assembly.
Referring to the drawings, there is illustrated an angle -type centrifuge rotor that is provided with a plurality of pockets 12 (six compartments or pockets in this instance) in which bottles 15 (of approximately 250 ml. or 500 ml.) are mounted. These bottles are at approximately a 28 angle to the vertic-al axis.
When centrifuging with an uncapped plastic bottle, the bottle cannot be filled, since there would be spillage from the top as the fluids in the bottle build up to a vertical circular Wall as the centrifugal force increases during acceleration. When centrifuging with a capped bottle, it has been found that with a rigid bottle such as made of stainless steel, the bottle will stand up under terrific centrifugal force developed Without breaking. In this invention, when centrifugal forces in excess of 20,000 times gravity at speeds in excess of 11,000 r.p.m. are to be considered, and when a polyethylene bottle is to be used and lled and sealed with a cap, the bottle 15, if it is not supported at its neck will distort and may rupture at the neck of the bottle. of bottle that is rather fragile, there is provided a cap assembly 16 for the bottle 15, and a reinforcing support- Therefore, to protect this typeV ing element 17 which may be threadably secured to retain the bottle neck and cap assembly in their proper relationship and prevent rupturing of said botle. The cap assembly is comprised of a stainless steel circular crown member 18 that covers and rests upon the top aperture or mouth of bottle 15. The crown member 18 is provided with a central aperture 19 and on the inner surface of the crown member there is a reduced portion 20 which provides a shoulder 21. A similar type element 22 of a smaller diameter is provided to be inserted within the mouth of said bottle 15, element 22 is similarly provided with a reduced portion 23 an-d a shoulder 24. Element 22 is not provided with a central aperture, but rather is provided with an extended threaded stud 25. A neoprene gasket v26 of a -fairly good thickness is inserted between elements 18 and 22, and with the stud 25 passing upward through the aperture 19 a nut 27 may be threadably secured to the stud 25 to retain the crown element 18 in juxtaposition to the gasket 26. This assembly may be inserted in the mouth of the bottle 15 and by turning nut 27 to draw element 22 toward element l, there will be a squeezing and distor-tion of the gasket 26 to thus provide a tight sealing cap assembly 16. With bottle 15 properly sealed with the cap assembly 16, the bottle 15 may be mounted in a pocket 12 of the rotor. It is apparent that if the rotor were operated at high speed with the bottle cap assembly so mounted, there would be a terrific distortion across the neck area of the bottle 15. Therefore, a supporting element 17 is mounted to surround the neck of the bottle. Supporting element 17 may be comprised of any rigid reinforcing material, such as aluminum, to provide the necessary strength. Element 17 at its base 29 is formed or cut on its inner periphery to fit the contour of the curved upper portion 15A of bottle 15, and the base portion 29, on its periphery, is circular in form, With a diameter to match the diameter of the rotor compartment 12. Element 17 may be formed on its inner periphery of the upper portion 30 -with a mating contour to mate with and match the outer periphery of the neck of bottle 15. The upper end of portion 30 is also provided with a cut out portion 31 to permit the crown member 1S to fit into portion 31 of element 17.
It is to be noted that the base portion 29 of the suppor-ting element 17 fits well within the bore of pocket 12 to provide a good solid support when the bottle 15 is mounted within pocket 12. The rest of the bottle is fully supported within the pocket of the rotor. It is apparent that when the rotor 10 is operated anda considerable centrifugal force is developed, this supporting element and cap assembly provides a rigid support for the polyethylene bottle 15 that is being utilized. With this supporting assembly, it is possible to -use a fairly light polyethylene bottle without danger of rupturing the bottle or losing the cap from the bot-tle due to any distortion.
Although a polyethylene bottle has been described as the preferable type of bottle to be used in this instance in an angle type centrifuge, other types of bottles, that is bottles constructed of other material of insufficient strength may be similarly used, without danger of breaking when supported in the manner illustrated herein, and this invention shall be limited only by the appended cl-airn.
What is claimed is:
In an angle type centrifuge, the combination of a central rotor, and a plurality of fragile distortable bottles that are to be mounted in said central rotor, said bottles having a sealing cap and a reduced neck portion, and a plurality of lightweight supporting elements that are cornposed of a rigid reinforcing material, each one to support the neck of a bottle and said sealing cap, said sealing cap tted and mounted within the neck of each bottle to seal said bottle, said rotor provided with a plurality of apertures, said bottles fitted into said apertures in said rotor, the necks of said bottles extending above said rotor, each supporting element tted to the reduced neck portion and extending slightly above said neck portion, and positioned to lit partially into the aperture in said rotor and each sealing cap abutting with the supporting element Where it extends above said neck portion to prevent distortion of said cap within the neck of said bottle.
References Cited in the le of this patent UNITED STATES PATENTS De Laval June 2l, 1887 Kimmel Mar. 21, 1916 Larsen Nov. 19, 1929 Levy Apr. 23, 1940 Grebmeier Aug. 17, 1948 Schoprneyer Nov. 28, 1950 Allen etal Ian. l1, 1955 Whitby Dec. 31, 1957 Szent-Gyorgyi et al May 13, 1958 Pickels et -al Mar. 24, 1959 FOREIGN PATENTS Switzerland Dec. 17, 1934
US814305A 1959-05-19 1959-05-19 Bottle support and cap assembly for centrifuge Expired - Lifetime US3071316A (en)

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Application Number Priority Date Filing Date Title
US814305A US3071316A (en) 1959-05-19 1959-05-19 Bottle support and cap assembly for centrifuge

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US814305A US3071316A (en) 1959-05-19 1959-05-19 Bottle support and cap assembly for centrifuge
US854281A US3050239A (en) 1959-11-20 1959-11-20 Centrifuge apparatus
DEC34478A DE1256921B (en) 1959-11-20 1964-11-25 Process for density gradient centrifugation in an ultracentrifuge and centrifuge for carrying out the process
US52577166A 1966-02-07 1966-02-07
US4838670A 1970-06-22 1970-06-22
GB1828471*[A GB1357231A (en) 1959-11-20 1971-06-22 Test apparatus for use in testing a liquid
AU47751/72A AU468478B2 (en) 1959-11-20 1972-10-13 Centrifuge clinical chemistry analysis system

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Cited By (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3133882A (en) * 1961-07-21 1964-05-19 Internat Equipment Company Centrifuges with retainers, retainers, and bottle stoppers for use therewith
US3219421A (en) * 1965-01-18 1965-11-23 Jr Robert Schwarz Tube for use in diagnostic and therapy control
US3265296A (en) * 1964-03-06 1966-08-09 Internat Equipment Company Plastic centrifuge bottles and caps therefor
US3447712A (en) * 1965-12-13 1969-06-03 Beckman Instruments Inc Centrifuge test tube cap
US3456876A (en) * 1966-03-23 1969-07-22 Beckman Instruments Inc Apparatus and articles for increasing the rate of particle separation and removal
US3459369A (en) * 1965-09-16 1969-08-05 Beckman Instruments Inc Centrifuge test tube cap
US3713775A (en) * 1959-11-20 1973-01-30 Bio Dynamics Inc Centrifuge clinical chemistry analysis system
US3938735A (en) * 1975-03-13 1976-02-17 Beckman Instruments, Inc. Capping assembly for thin all centrifuge tubes
US3998383A (en) * 1975-07-16 1976-12-21 E. I. Du Pont De Nemours And Company Gradient separation apparatus
US4007013A (en) * 1975-09-22 1977-02-08 Contraves Ag Holder device for sample vials or the like for an analysis apparatus
FR2427846A1 (en) * 1978-06-05 1980-01-04 Beckman Instruments Inc ONE PIECE CENTRIFUGAL TUBE
EP0021599A1 (en) * 1979-06-18 1981-01-07 Beckman Instruments, Inc. Seal arrangement for a centrifuge rotor cavity
US4372483A (en) * 1981-05-29 1983-02-08 Beckman Instruments, Inc. Fluid containment annulus for fixed angle rotors
EP0035829B1 (en) * 1980-02-19 1985-05-15 Beckman Instruments, Inc. Supporting cap and spacer for centrifuge tubes
DE8700742U1 (en) * 1987-01-16 1987-05-14 Herolab GmbH Laborgeräte, 6837 St. Leon-Rot Centrifuge tubes with cap
US4787971A (en) * 1987-01-23 1988-11-29 Alan Donald Miniaturized column chromatography separation apparatus and method of assaying biomolecules employing the same
US4830209A (en) * 1988-05-09 1989-05-16 Multi-Technology Inc. Fail safe releasible locks for cappped disposable centrifuge containers
US4874102A (en) * 1988-05-09 1989-10-17 Multi-Technology Inc. Medical fail safe releasible locks and/or seals for capped disposable centrifuge containers, cryogenic vials and the like
US4883644A (en) * 1987-12-09 1989-11-28 Brandeis University Microtube vortexer adapter and method of its use
US4896780A (en) * 1988-05-09 1990-01-30 Multi-Technology Inc. Fail safe releasible locks for capped disposable centrifuge containers
US4902270A (en) * 1988-10-03 1990-02-20 Nalge Company Centrifuge tube
US4953741A (en) * 1988-05-09 1990-09-04 Multi-Technology Inc. Medical fail safe releasible locks and/or seals for capped disposable centrifuge containers, cryogenic vials and the like
US4956103A (en) * 1988-05-09 1990-09-11 Multi-Technology Inc. Fail safe releasible locks for capped disposable centrifuge containers
US5011663A (en) * 1987-07-22 1991-04-30 S E A C S.R.L. Multitest-tube for clinical chemistry analysis for several simultaneous tests
US5127895A (en) * 1990-03-30 1992-07-07 Beckman Instruments, Inc. Self-seal centrifuge tube
US5318749A (en) * 1991-05-14 1994-06-07 Firma Andreas Hettich Centrifugation chamber for liquor testing
WO1994022584A1 (en) * 1993-04-02 1994-10-13 Beckman Instruments, Inc. Supporting spacer for self-sealing centrifuge tubes
US5901873A (en) * 1997-04-25 1999-05-11 Beckman Instruments, Inc. Self-seating self-sealing labware adapter
US6170690B1 (en) 1997-05-09 2001-01-09 Shin-Etsu Polymer Co., Ltd. Air-tightly sealable container with bell jar covering
WO2001002255A2 (en) * 1999-07-01 2001-01-11 Kendro Laboratory Products, L.P. A container assembly having a support bridge
US20090054221A1 (en) * 2007-08-21 2009-02-26 Nalge Nunc International Centrifuge bottle closure and assembly thereof
US20100331163A1 (en) * 2009-06-30 2010-12-30 Hitachi Koki Co. Ltd. Centrifugal separator
JP2011011130A (en) * 2009-06-30 2011-01-20 Hitachi Koki Co Ltd Centrifugal separator

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Publication number Priority date Publication date Assignee Title
US365120A (en) * 1887-06-21 de layal
US1176463A (en) * 1914-11-30 1916-03-21 Joseph P Kimmel Pipe-testing plug.
US1736350A (en) * 1926-02-26 1929-11-19 Forenede Bryggerier As Closing device for containers made of aluminum or other soft metals
CH172064A (en) * 1933-09-13 1934-09-30 Carba Ag Closure device on high pressure vessels.
US2198256A (en) * 1938-04-11 1940-04-23 Henri G Levy Centrifuge tube
US2447330A (en) * 1946-05-16 1948-08-17 Grebmeier Joseph Rotor for ultracentrifuge machines
US2531745A (en) * 1947-11-18 1950-11-28 Clifford S Schopmeyer Squeeze-bottle atomizer for acid liquids
US2699289A (en) * 1950-09-02 1955-01-11 Custom Scient Instr Inc High-speed centrifuge
US2817970A (en) * 1953-01-02 1957-12-31 Pillsbury Mills Inc Apparatus for determining the particle size distribution of finely divided materials
US2834541A (en) * 1956-09-20 1958-05-13 Sorvall Inc Ivan Centrifuging apparatus and system
US2878992A (en) * 1956-12-28 1959-03-24 Beckman Instruments Inc Centrifuge apparatus and rotor therefor

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US365120A (en) * 1887-06-21 de layal
US1176463A (en) * 1914-11-30 1916-03-21 Joseph P Kimmel Pipe-testing plug.
US1736350A (en) * 1926-02-26 1929-11-19 Forenede Bryggerier As Closing device for containers made of aluminum or other soft metals
CH172064A (en) * 1933-09-13 1934-09-30 Carba Ag Closure device on high pressure vessels.
US2198256A (en) * 1938-04-11 1940-04-23 Henri G Levy Centrifuge tube
US2447330A (en) * 1946-05-16 1948-08-17 Grebmeier Joseph Rotor for ultracentrifuge machines
US2531745A (en) * 1947-11-18 1950-11-28 Clifford S Schopmeyer Squeeze-bottle atomizer for acid liquids
US2699289A (en) * 1950-09-02 1955-01-11 Custom Scient Instr Inc High-speed centrifuge
US2817970A (en) * 1953-01-02 1957-12-31 Pillsbury Mills Inc Apparatus for determining the particle size distribution of finely divided materials
US2834541A (en) * 1956-09-20 1958-05-13 Sorvall Inc Ivan Centrifuging apparatus and system
US2878992A (en) * 1956-12-28 1959-03-24 Beckman Instruments Inc Centrifuge apparatus and rotor therefor

Cited By (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3713775A (en) * 1959-11-20 1973-01-30 Bio Dynamics Inc Centrifuge clinical chemistry analysis system
US3133882A (en) * 1961-07-21 1964-05-19 Internat Equipment Company Centrifuges with retainers, retainers, and bottle stoppers for use therewith
US3265296A (en) * 1964-03-06 1966-08-09 Internat Equipment Company Plastic centrifuge bottles and caps therefor
US3219421A (en) * 1965-01-18 1965-11-23 Jr Robert Schwarz Tube for use in diagnostic and therapy control
US3459369A (en) * 1965-09-16 1969-08-05 Beckman Instruments Inc Centrifuge test tube cap
US3447712A (en) * 1965-12-13 1969-06-03 Beckman Instruments Inc Centrifuge test tube cap
US3456876A (en) * 1966-03-23 1969-07-22 Beckman Instruments Inc Apparatus and articles for increasing the rate of particle separation and removal
US3938735A (en) * 1975-03-13 1976-02-17 Beckman Instruments, Inc. Capping assembly for thin all centrifuge tubes
US3998383A (en) * 1975-07-16 1976-12-21 E. I. Du Pont De Nemours And Company Gradient separation apparatus
FR2317966A1 (en) * 1975-07-16 1977-02-11 Du Pont PROCESS AND APPARATUS FOR GRADIENT SEPARATION
US4007013A (en) * 1975-09-22 1977-02-08 Contraves Ag Holder device for sample vials or the like for an analysis apparatus
FR2427846A1 (en) * 1978-06-05 1980-01-04 Beckman Instruments Inc ONE PIECE CENTRIFUGAL TUBE
EP0021599A1 (en) * 1979-06-18 1981-01-07 Beckman Instruments, Inc. Seal arrangement for a centrifuge rotor cavity
EP0035829B1 (en) * 1980-02-19 1985-05-15 Beckman Instruments, Inc. Supporting cap and spacer for centrifuge tubes
US4372483A (en) * 1981-05-29 1983-02-08 Beckman Instruments, Inc. Fluid containment annulus for fixed angle rotors
DE8700742U1 (en) * 1987-01-16 1987-05-14 Herolab GmbH Laborgeräte, 6837 St. Leon-Rot Centrifuge tubes with cap
US4787971A (en) * 1987-01-23 1988-11-29 Alan Donald Miniaturized column chromatography separation apparatus and method of assaying biomolecules employing the same
US5011663A (en) * 1987-07-22 1991-04-30 S E A C S.R.L. Multitest-tube for clinical chemistry analysis for several simultaneous tests
US4883644A (en) * 1987-12-09 1989-11-28 Brandeis University Microtube vortexer adapter and method of its use
US4896780A (en) * 1988-05-09 1990-01-30 Multi-Technology Inc. Fail safe releasible locks for capped disposable centrifuge containers
US4874102A (en) * 1988-05-09 1989-10-17 Multi-Technology Inc. Medical fail safe releasible locks and/or seals for capped disposable centrifuge containers, cryogenic vials and the like
US4953741A (en) * 1988-05-09 1990-09-04 Multi-Technology Inc. Medical fail safe releasible locks and/or seals for capped disposable centrifuge containers, cryogenic vials and the like
US4956103A (en) * 1988-05-09 1990-09-11 Multi-Technology Inc. Fail safe releasible locks for capped disposable centrifuge containers
US4830209A (en) * 1988-05-09 1989-05-16 Multi-Technology Inc. Fail safe releasible locks for cappped disposable centrifuge containers
US4902270A (en) * 1988-10-03 1990-02-20 Nalge Company Centrifuge tube
US5127895A (en) * 1990-03-30 1992-07-07 Beckman Instruments, Inc. Self-seal centrifuge tube
US5318749A (en) * 1991-05-14 1994-06-07 Firma Andreas Hettich Centrifugation chamber for liquor testing
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