US2663461A - Container for pharmaceuticals and the like - Google Patents

Container for pharmaceuticals and the like Download PDF

Info

Publication number
US2663461A
US2663461A US102372A US10237249A US2663461A US 2663461 A US2663461 A US 2663461A US 102372 A US102372 A US 102372A US 10237249 A US10237249 A US 10237249A US 2663461 A US2663461 A US 2663461A
Authority
US
United States
Prior art keywords
capsule
lips
sealing
container
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US102372A
Other languages
English (en)
Inventor
Frank E Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to US102372A priority Critical patent/US2663461A/en
Priority to DK199950AA priority patent/DK82541C/da
Priority to DEB5645A priority patent/DE894609C/de
Priority to DEB2641U priority patent/DE1677219U/de
Priority to FR1021004D priority patent/FR1021004A/fr
Priority to CH294535D priority patent/CH294535A/fr
Priority to GB16324/50A priority patent/GB677592A/en
Application granted granted Critical
Publication of US2663461A publication Critical patent/US2663461A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06—Ampoules or carpules
    • A61J1/067—Flexible ampoules, the contents of which are expelled by squeezing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D35/00—Pliable tubular containers adapted to be permanently or temporarily deformed to expel contents, e.g. collapsible tubes for toothpaste or other plastic or semi-liquid material; Holders therefor
    • B65D35/44—Closures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/20—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge
    • B65D47/2018—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure
    • B65D47/2031—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure the element being formed by a slit, narrow opening or constrictable spout, the size of the outlet passage being able to be varied by increasing or decreasing the pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/40—Packages formed by enclosing successive articles, or increments of material, in webs, e.g. folded or tubular webs, or by subdividing tubes filled with liquid, semi-liquid, or plastic materials
    • B65D75/44—Individual packages cut from webs or tubes
    • B65D75/48—Individual packages cut from webs or tubes containing liquids, semiliquids, or pastes, e.g. cushion-shaped packages
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52—Details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52—Details
    • B65D75/58—Opening or contents-removing devices added or incorporated during package manufacture
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52—Details
    • B65D75/58—Opening or contents-removing devices added or incorporated during package manufacture
    • B65D75/5805—Opening or contents-removing devices added or incorporated during package manufacture for tearing a side strip parallel and next to the edge, e.g. by means of a line of weakness
    • B65D75/5811—Opening or contents-removing devices added or incorporated during package manufacture for tearing a side strip parallel and next to the edge, e.g. by means of a line of weakness and defining, after tearing, a small dispensing spout, a small orifice or the like
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S206/00—Special receptacle or package
    • Y10S206/82—Separable, striplike plural articles

Definitions

  • This invention relates to a dispensing-type capsule or container, and more particularly to a dispensing-type capsule for dispensing individual or metered quantities of a contained ma terial.
  • the invention is particularly well suited to a single-dosage, single-use, throw-away type unit for discharging a single or metered dosage of the contained material.
  • This contained material may be, for example, a pharmaceutical preparation, such as any of the various medicaments, dentifrices, shampoos, disinfectants, deodorants. suntan lotions, ointments, dermatological preparations, etc., or materials for other uses, such as incremental portions of paints or pigments therefor, oils or greases, chemicals, edible products, fiavorings or seasonings, glues, etc. to specify only a few of the various classes of contained material. Additionally, these contained materials may be liquids, jellies, creams, pastes, semi-fluids, semi-solids, solids in tablet or subdivided form, powders, suspensions, emulsions, etc.
  • single-dosage is used herein in a broad sense as referring to any contained material present in a predetermined or metered amount to be substantially totally expelled for a single-use purpose. While the provision of a single-dosage dispenser is among the more important objects of the invention, the invention can also be used for multiple-dosage storage of contained material which is to be hermetically, bacterially or sanitarily sealed prior to expelling the first dosage.
  • the family-size toothpaste container is one of the worst oifenders in spreading mouth infections, such as Vincents angina.
  • the present invention provides a cheap and effective container for pharmaceuticals and the like which is effectively sealed until used, the seal being easily ruptured as a part of the material-expelling operation and without the preceding application of solvents, tearing, cutting, piercing or other mechanical operations.
  • a container which effectively seals the contained material, from the time of filling to the time of use, against entry of air, moisture, germs, bacteria, etc. yet which provides an applied or tensionally-weak sealing means which is readily rupturable by pressure developed internally of the container as a part of the expelling operation and without using any of the opening expedients mentioned above.
  • a container which provides a normallycollap-sed discharge opening with side walls lying adjacent and substantially in contact with each other and which side walls separate at the discharge opening upon advancement of the contained material toward the opening, this advancement tending to spread the walls, break a tensionally-weak seal thereadjacent and form the discharge opening into an orifice of a size and shape desired for expelling the contained material.
  • (C) A container in which a discharge opening is hermetically and bacterially sealed by a mass of container-adhering sealing material more readily rupturable than the container and rupturable solely by increase in internal pressure in the container induced usually by squeezing thereof.
  • (G) A container which can be economically formed and which has sealed portions spaced from each other to define an expelling passage for the contai ed material.
  • Fig. 1 illustrates successive steps inv the manuiacture of the preferred type pf capsule in views A-E, inclusive;
  • Fig. 2 illustrates a final or sealing operation
  • Fig. 3 is an enlarged elevational view of the preferred form of capsule
  • Fig. i is a side view of same, taken in the direction of arrow i of Fig. 31; V
  • Fig. 5 is a vertical sectional view taken along the line of Fig. 3;
  • Fig. 6 illustratesa modification in which coated stock is employed
  • Fig. 7 illustrates a further modification in which the container or capsule is coated after being sealed
  • Fig. 8 illustrates a series of adhering capsules, arranged in one manner
  • Fig. 9 illustrates a series of adhering capsules, arranged in another manner.
  • Fig. 10 is a perspective view illustrating the manner of use of the invention.
  • the invention can best be described by the sequence of manufacture views of Figs. 1 and 2, taken with the enlarged. views of Figs. 3-5. It will be understood, however, that the capsules of the latter figures can be formed by sequences other than those illustrated in Figs. 1 and 2 and that these sequences are illustrative of a preferred manner of forming the capsule from tubular-stock thermoplastic material. Similar methods starting with a tubular material formed by heat sealing an edge of a folded sheet or by heat sealing the edges of two sheets of thermoplastic material will be obviou to those skilled in the art from the illustrated example.
  • FIG. 1 illustrates a pre-cut length of tubular-stock material.
  • the length of tubular-stock material, indicated at it is formed of a pliable but substantially nonstretchable thermoplastic material which can be sealed by heat, applied by a hot element or by induction means. Examples of preferred materials will be later given.
  • View B of Fig. 1 illustrates the operation of heat-sealing the rear end of the tube It by pressing the adjacent side walls together and applying heat to form a closed or sealed end H of the completed container or capsule [2, shown in Fig. 3.
  • This operation provides within a body portion is of the capsule a storage zone It.
  • the next operation involves partial filling of the container or capsule and substantially complete filling of the storage zone M by the material l5 to be dispensed, care being exercised to deposit this material in the bottom of the container or capsule and care being exercised to avoid coating the upper inner walls of the tubular stock with such material.
  • the next step is to heat-seal side portions of the tubular stock at a position beyond the mate rial i5 by squeezing together and applying heat to side zones of the tubular stock, preferably followed by trimming, as suggested in views D and E of Fig. 1.
  • the preferred procedure is to collapse or flatten the open end of the tubular stock and apply heat in an irregular zone, suggcstedinviewD as including side bands ii and i8 and intersecting tip bands 59 and 28. If desired, the walls may be sealed not only in these bands but also at positions beyond or outside thereof.
  • the following step illustrated in view E of Fig. -1, involves trimming away the excess material outside the bands ii and iii and cutting along the line AA, substantially at the base of the tip bands is and ill, to present cleanlytrimmed'edges or lips '22 of the side walls and 23, best illustrated in Fig. 5.
  • the capsule l2 When thus trimmed, the capsule l2 provides edge-sealed side portions 25 and substantial- 1y coextensive with or formed'ii'orn the side bands I? and 8.
  • the side portions and 2% are spaced from each other to provide an expelling passage 27 opening on the storage zone i l and extending to the .lips 22. it is preferred, although not absolutely essential, that this passage converge toward the lips 22 in the plane of the .paper in Fig. 3.
  • the walls 23 and 24 and the intervening passage 2"! will usually converge toward the lips 22 a plane transverse to such plane, namely, in the plane of the paper in Fig.
  • progressive sections taken transversely through a neckportion of the capsule i2 will be substantially oval in shape, the minor axis of the oval progressively decreasing toward the lips 22 and the major axis preferably decreasing in that section of the neck portion 22 which is closest and integral with the body portion l3.
  • the remaining section of the expelling passage 2?, closer to the lips 22, may desirably be of uniform width, measured along such major axis to shape the contained material is prepa ra-tory to. ejection.
  • Such lips normally lie in contact with or very close to each other in side-by-side relationship and form a potential discharge orifice the being spreadable by increase in pressure within the container or capsule to form a discharge orifice, usually of substantially oval shape, through which the material 15 may be expelled.
  • the lips 22 normally lie adjacent each other but are spreadable by increase in internal pressure, set up by squeezing the container Or capsule, to separate and form the discharge orifice.
  • the material lE forced along the ex elliug passage 2'? by the external pressure, will tend to swell or separate the central portions of the walls 23 and 2 5, thus creating a force tending to separate the lips 22. This force is relied upon to rupture a seal adjacent the lips 22.
  • the potential discharge orifice SR2 and the lip 22 are sealed by a pressure-rupturable sealing means which serves to join the lips and hold them close to each other.
  • the sealing means should have a tensile strength less than that of the container or capsule to be rupturable by the aforesaid force or internal pressure induced by squeezing.
  • the preferred pressure-rupturable sealing means comprises a mass of a sealing substance applied to the exterior of the container or capsule, preferably immediately adjacent the lips 2?. to extend across these lips in sealing relationship.
  • Thesealing substance 33 should also preferably extend at least a small distance along the walls 23 and 25 to increase the area of contact. A portion of the sealing substance should extend beyond the extremities of the lips 22 to provide a hermetic and bacterial seal for the capsule and its contained material.
  • the preferred manner of forming the mass of sealing substance 33 is to contact the lips 22 while substantially closed. with a semi-fluid sea1- ing substance.
  • Fig. 2 shows one way of accomplishing this, namely, by inverting the capsule, dipping the lips 22 momentarily in a body of molten sealing substance til held in a container 35, raising the capsule with a glob of the sealing substance adhering to the lips and cooling the substance to form the mass of sealing substance 33, shown in Figs. 25.
  • the sealing substance should preferably be in a rather viscous state, the vi cosity determining in part the amount of material picked up from the larger mass of the sealing substance.
  • the sealing substance may be any material that will bond to and seal the lips 22, yet which will not be meltable in storage or in use, preferably a substance which is not water soluble.
  • the mass of sealing substance should be of lower tensile strength than the capsule or container itself, whereby squeezinginduced internal pressure will cause rupture only of the mass of sealing substance 33, this mass ordinarily separating under tension at or near the plane of contact or adjacency of the lips 22, leaving a portion of the mass of sealing substance adhering to each of the side walls 23 and E i.
  • the material is a paste-like material, such as toothpaste.
  • the entrapped air or other gas will not harden the surface of the paste-like material, becoming soon saturated with volatile components thereof. Additionally, the entrapped serves the very useful purpose of applying the spreading force to the side Walls 23, 22 used to rupture the seal and separate the lips 22. This means that the gas will open th discharge orifice prior to the time that the paste-like material reaches this orifice, thereby preventing any initial surge of the paste-like material through the orifice upon rupture of the sealing substance.
  • the body material is preferably a resin-type thermoplastic material, as is also the sealing substance, the latter having different physical properties as compared with th former.
  • the particular thermoplastic material used will depend in part on the product to be marketed in the capsule. If this product contains essential oils, this may determine the selection of the body material if the escape of vapors of such oils is to be avoided.
  • two types of body material, particularly advantageous in the present invention will be described, together with appropriate sealing substances for therewith.
  • thermoplastic body material is a highly polymerized ethylene, such as polyethylene or polyethylene resin.
  • ethylene such as polyethylene or polyethylene resin.
  • Such roducts are currently manufactured, in several commercial grades, and are essentially linear poly-' mers of ethylene. produced by the direct polymerization of ethylene at high temperatures and high pressure. These materials are character-- ized by low moisture vapor transmission, good chemical resistance, heat scalability, non-toxicity, complete lack of odor and taste, and inherent flexibility even at temperatures below (3 C.
  • the products known as polyethylene grades DYLT or DYNH have been found suitable and have a melting point of about 300-350 F.
  • a similar material, known as polythene can also be used.
  • the tube Hl may have a wall thickness of about .003-.010", a wall thickness of .005" being quite satisfactory.
  • the above materials often will not form satisfactory barriers for the vapors of essential oils, particularly with the small wall thicknesses contemplated. For example, if toothpaste is marketed therein, a faint odor of the flavoring oils can be detected exteriorly of the capsule, even though the discharge orifice 39 is adequately sealed against transmission of such vapors.
  • Saran is a co-polymer of vinylidene chloride and is available in severalv grades. Grade S-51'7 is cited, by way, of example, as suitable, although other formulations of this product can be successfully employed as the body material. This product can be readily heat sealed at about 290310 F. and is readily extrudable, temperatures of about l50--.'550" F.
  • the preferred wall thicknesses of Saran are substantially less than those preferred for the polyethylene type material, being in the neighborhood of about .002.005" and thus forming an extremely pliable body material.
  • the sealing substance 33 may be any pressurerupturable material having the properties outlined earlier. I prefer to use a thermoplastic resin as the sealing substance, selecting the material to be of lower tensile strength than the body material. Often, the sealing substance can be of the same type as the body substance but of lower molecular weight and lower melting point.
  • the sealing substance may be a lower-molecular weight polyethylene, such as polyethylene DXL-fl having a melting point of about 250 F., sumciently below the melting point of the body ma: terial so that contact of the sealing substance with the body material will not melt the latter or induce a temperature sufficient to fuse the lips 22 directly together.
  • Saran is employed as the body material
  • a lower-molecular weight Saran may be eme 7 prcyedas thesea'ling substance, typically a prod uct having an extrusion temperature of, around 200 F.
  • a suitable polyethylene sealingsub'stance can be employed with a Saran body material if the former is of sufuciently low molecular weight to have a tensile strength and a rlfrelting point respectively less than the tensile strength and bonding temperature of the latter.
  • both polyethylene and Saran have nonporous surfaces to which the usual adhesives will notstick.
  • the resin-type mass ofsealing substance 33 will not be permanently, integrally or tightly bonded or adhered to the body material, the bonding or adhesion with which the invention is concerned, when employing a s1 tic sealing substance against a plastic b y ate'rial, being looser and representing an adhesion or bonding arising more from surface irregularities of 'thebo'd'y material.
  • sealing substance encircles or encompasses the lips as 'a ring to form a mechanical lock, particularly if, as is desirable, a portion of the mass of sealing substance extends in contact with the sidewalls 23 and 2'4 for a small distance from the edges of the lips.
  • the mass of sealing substances can usuallybe pulled from the lips in cap-like form a fingernailor blunt knife blade.
  • the dhesion is sufiicient to hold the sealing subs't a tie in place during all normal handling of the eat H e
  • the mass of sealing substance breaks under tension in substantially the plane ofthe potential discharge orifice 36, leaving one 'portibn of the mass of sealing substance still adher to ene'of the side walls and another portion still "adhering to the other side wall.
  • the tubular stdck initially comprises a base material 31 with interior and exterior coatings 38 and 39 of a suit-'- able thermoplastic resin, such as Saran or f polyethylene. Coatings of such materials can be applied to any number of flexible base materials, such as papen cloth, other thermoplastic ma er'ials. etc. Any such flexible material can be employed as the base material 31.
  • the base material 3'! may be a polyethylene material and the coatings 38 and 39 may be a Saran material to increase the barrier against vapors.
  • Saran or polyethylene may be coated over paper, cloth, or other flexible but substantially nonstretchable material as the base material 37.
  • the previously-described sealing substance 33 can be applied to, any "such laminated body portion l3 and capan otherwise be made by the same steps as usly outlined. itionally, it is not invariably necessary to use both internal and external coatings when employing a laminated body portion iii. For exan 1' e, merely a very thin coating of Saran 21 led interiorly or exteriorly will often sumce "to provide a sufficient vapor barrier even if the base material 31 is quite permeable to vapors.
  • the base material 37 With only an exterior coating of the base materm '37, the latter may be in direct contact with the contained material, in which event it should 8. be relatively inert thereto. if the base material 37 is coated'only on its inner side, it will be made of a material forming a satisfactory exterior for the capsule. Most any such base material will provide a satisfactory base for the sealing substance 33.
  • the sealing substance 33 will bridge across the closed lips. However, Whether the sealing "substance is applied by dipping or by otherwise applying a small mass of the fluid sealing substance to the lips, a portion of the sealing substance may enter the discharge orifice, particularly if the lips are not entirely in surface contact. Any of the sealing substance which thus enters the potential discharge orifice will act as an additional seal and yet will not interfere with the pressural breaking of the seal as previously described.
  • a coated base material as in Fig. 6, it is possible to coat exteriorly a finished capsule, made as suggested in Figs. 1-5, to decrease its vapor permeability or to form an additional protective coating thereon.
  • Fig. '7 which shows, greatly enlarged, the discharge end of a capsule, formed as in Fig. 5, the complete capsule being dipped into a coating solution to form an external film 35' covering the entire capsule, with the exception of the mass of sealing substances 33. It is usually not desirable to coat the latter as the coating itself would tend to reinforce and to prevent rupture of the seal when the pressure inside the capsule is increased by squeezing thereof.
  • the coating solution may be molten Saran of lower melting point than the base material 31 or it may be Saran or other thermoplastic resin in solution, the solvent readily vaporizing to leave the coating 39'.
  • a solution of Saran in methylethylketone will usually befound satisfactory and will apply a thin vapor-barrier film to a capsule formed of polyethylene or other plastic material.
  • a plurality of the containers or capsules l2 may be marketed while packed in a suitable box or they may be dispensed one at a time from any suitable dispenser, whether or not coin operated.
  • Fig. 3 shows a plurality of the capsules i2 joined or adhered side by side in a common plane. This is facilitated by the shape of the capsules previously described as the end portion Ii and the sid portions 25, 25 provide adhering zones in the form of tips 30 extending outwardly of the body portion 13, these tips being suitably connected to corresponding tips of an adjacent capsule.
  • small masses M of any suitable adhering substance locally join the adhering zones of adjacent capsules as b bridging or adhering the correspondingtips All; thereof.
  • the masses 4! maybe small portions of the same tensionally-Weak substance as was used to seal the capsules, e. g., "polyethylene grade DXL- l, men tioned above.
  • the capsules can be stacked face to face and a small mass of such adhering substance placed between contiguous side walls or faces of the body portions of adjacent capsules.
  • Fig. 9 shows another manner Of temporarily adhering a serics of the capsules by use of small masses #2 of an adhering substance joining adboring zones of adjacent capsules, e. g., joining the mass of sealing substance 33 of one capsule with the opposite end of the next capsule.
  • the adhering substance should preferably be merely temporarily connected to the end of the next capsule, to separate therefrom without rupture of the sealing substance, or the adhering substance should be of even less tensional strength than the sealing substance 83, either because of a lesser thickness or size or because of being made of a substance having less tensile strength than that of the sealing substance.
  • a capsule In use, a capsule is severed from the series by a slight pull. While still sealed, it is placedin the locale of the desired expulson of the contents, e. g., above a toothbrush, By squeezing the walls of the body portion is between the fingers, as suggested in Fig. 10, the internal pressure will be built up and the contents will be advanced along the expulsion passage 2'8, both actions tending to spread the side walls 23, 2 to break the seal formed by the mass 33 of the sealing substance. Ihe squeezing is preferably progressive, starting adjacent the rear end of the capsule and advancing toward the expelling end. This is easily accomplished by a rolling of the finger tips along the capsule to induce the squeezing. If the capsule is small, its entire contents may be expelled by a single squeeze but if the capsule is larger or the users fingers smaller, it may require a second or advanced grip on the capsule to expel its contents.
  • the orifice 3t preferably opens into oval shape when expelling substances such as toothpaste, thus applying a flat layer of the paste to the toothbrush.
  • a dispensing-type capsule for containing and dispensing a dosage of a contained material, said capsule including: a hollow body portion providing a storage zone adapted to contain said material, said body portion having closed end and an expelling end; a neck portion integral with said expelling end of said body and comprising a pair of walls substantially collapsed at their ends to form a pair of lips lying adjacent each other but spreadable to form a discharge orifice for such material, said walls converging toward each other when said lips are adjacent each other to form a material-receiving passage opening on said storage zone, the plane toward which said walls converge being at right angles to the plane of said lips when adjacent each other, and said material-receiving passage also converging toward said lips in the plane of said lips, said body and neck portions being formed of tubularstocl: pliable material which when squeezed will advance said material along said passage toward said lips to impose a force on said walls tending to separate said lips and enlarge said discharge orifice; said necl: portion being provided
  • a capsule as defined in claim 2 in which a small body of gas is provided between the material filling and sealing substance, said gas being compressed on squeezing to rupture the sealing sub stance and thereby spreading the lips prior to the time the material filling reaches the lips.
  • a dispensing-type capsule comprising: heat-sealing an end of a tubular-stock, pliable, thermoplastic material to close said ends and provide a container; partially filling said container with the material to be dispensed; transversely heat-sealing the open end of the tubular stock at a position spaced from said material and heat-sealing spaced opposite side portions thereof from said transverse seal toward said material leaving the space there'between unsealed and trimming said transversely heat-sealed previously open end to provide normally-adjacent lips at the terminus of the expelling passage between said said portions; and sealing the filled container by contacting said lips with a fluid sealing substance to provide a mass of said substance adhering to and closing the lips but of such tensile strength as to be rupturable on squeezingeinduced pressure inside the capsule.
  • a dispensing-type capsule for containing and dispensmg a dosage of a contained material, said capsule including: a hollow body portion providing a storage zone adapted to contain said material, said body portion having a closed end and an expelling end; a neck portion integral with said expelling end of said body and comprising a pair of walls substantially collapsed at their ends to form a pair or" lips lying in mutual contact but spreadable to form a discharge orifice for such material, said body and neck portions being formed of tubular-stock pliable material which when squeezed will advance said material along said passage toward said lips to impose a force on said walls tending to separate said lips and enlarge said discharge orifice; said walls being sealed together in face-to-face relation on opposite sides of said neck portion with the portion therebetween being unsealed and de ning said discharge orifice; said discharge orifice being of 11 substantially less transverse dimension than said.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Laminated Bodies (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Closures For Containers (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
US102372A 1949-06-30 1949-06-30 Container for pharmaceuticals and the like Expired - Lifetime US2663461A (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
US102372A US2663461A (en) 1949-06-30 1949-06-30 Container for pharmaceuticals and the like
DK199950AA DK82541C (da) 1949-06-30 1950-06-14 Portionskapsel og fremgangsmåde til dens fremstilling.
DEB5645A DE894609C (de) 1949-06-30 1950-06-24 Kapsel zur Aufnahme und Ausgabe von Materialien aller Art
DEB2641U DE1677219U (de) 1949-06-30 1950-06-24 Kapsel zur aufnahme und ausgabe von materialien aller art.
FR1021004D FR1021004A (fr) 1949-06-30 1950-06-27 Récipient pour produits pharmaceutiques et analogues
CH294535D CH294535A (fr) 1949-06-30 1950-06-29 Emballage, notamment pour produits pharmaceutiques, et procédé de fabrication de cet emballage.
GB16324/50A GB677592A (en) 1949-06-30 1950-06-29 Container for pharmaceuticals and the like

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US102372A US2663461A (en) 1949-06-30 1949-06-30 Container for pharmaceuticals and the like

Publications (1)

Publication Number Publication Date
US2663461A true US2663461A (en) 1953-12-22

Family

ID=22289495

Family Applications (1)

Application Number Title Priority Date Filing Date
US102372A Expired - Lifetime US2663461A (en) 1949-06-30 1949-06-30 Container for pharmaceuticals and the like

Country Status (6)

Country Link
US (1) US2663461A (fr)
CH (1) CH294535A (fr)
DE (2) DE894609C (fr)
DK (1) DK82541C (fr)
FR (1) FR1021004A (fr)
GB (1) GB677592A (fr)

Cited By (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2792149A (en) * 1954-10-28 1957-05-14 Joseph M Lutz Collapsible capless tube for toothpaste or the like
US2802608A (en) * 1954-10-18 1957-08-13 Joseph A Hull Sealed valve dispensing device
US2808926A (en) * 1954-11-10 1957-10-08 Blair M Drake Single dose vial assembly of animal semen
US2861572A (en) * 1957-04-09 1958-11-25 Barnes Hind Lab Inc Medicament dispenser
US2875762A (en) * 1957-09-17 1959-03-03 Jr Carl W Middleton Suppository holder
US2908601A (en) * 1957-05-16 1959-10-13 Unette Corp Manufacture of internal pressure-rupturable seal in thermoplastic tubing
US2944706A (en) * 1957-04-29 1960-07-12 Alfred A Moore Collapsible container and dispensing holder therefor
US2947448A (en) * 1957-07-23 1960-08-02 Duane C Maddux Collapsible tube closure and sealing means
US2962192A (en) * 1958-09-10 1960-11-29 Ivers Lee Co Package for fluent commodities
US2970723A (en) * 1952-12-16 1961-02-07 Flax Valer Manufacture of collapsible tubular container made of flexible materials
US3075528A (en) * 1958-11-26 1963-01-29 Astra Ab Laminated hypodermic syringe ampul
US3152727A (en) * 1961-09-26 1964-10-13 Mayer & Co Inc O Reclosable dispensing package
US3156383A (en) * 1962-04-05 1964-11-10 Maison Ind Tecnico Chimiche Ne Expansible single use dispensing container
US3171412A (en) * 1956-06-15 1965-03-02 Brann Bernd Container for biological liquids
US3178065A (en) * 1963-01-22 1965-04-13 Tubed Chemicals Corp Impermeable collapsible tube
US3184121A (en) * 1963-08-01 1965-05-18 Ivers Lee Co Package with self sealing closure
US3189227A (en) * 1962-12-07 1965-06-15 American Home Prod Fluid dispenser
US3221942A (en) * 1963-07-25 1965-12-07 Polaroid Corp Collapsible fluid container
US3234069A (en) * 1962-10-09 1966-02-08 Szasz Frank Package manufacturing apparatus
US3306567A (en) * 1964-08-20 1967-02-28 Gen Motors Corp Flexible bag for making ice cubes
US3308940A (en) * 1965-08-11 1967-03-14 Jr Theodore Morris Clinical thermometer device
US3338794A (en) * 1964-11-23 1967-08-29 Swift & Co Culturing anaerobic bacteria
US3463358A (en) * 1968-01-11 1969-08-26 Roy F Wenzler Material spreader means
US3523628A (en) * 1968-01-18 1970-08-11 Lee B Colvin Container for cyanoacrylate adhesive
US3652174A (en) * 1968-03-25 1972-03-28 Philip Boone Hermetically-sealed products and related method for cleansing and other uses
US3815794A (en) * 1972-03-02 1974-06-11 R Carlisle Plastic-film containers with self-sealing orifices
US3917120A (en) * 1971-11-11 1975-11-04 Merck Patent Gmbh Single use container for liquid pharmaceutical compositions
US3971376A (en) * 1973-02-26 1976-07-27 Ceskoslovenska Akademie Ved Method and apparatus for introducing fluids into the body
US3989045A (en) * 1972-09-29 1976-11-02 Eck William F Van Hypodermic syringe
US4135883A (en) * 1977-08-29 1979-01-23 Bio-Dynamics Inc. Blood analyzer system
US4159077A (en) * 1976-12-09 1979-06-26 W. R. Grace & Co. Process for closing a flexible container and the container formed thereby
US4252257A (en) * 1978-10-10 1981-02-24 Herzig Albert M Automatic closure for containers having a pinch-off fold
US4328912A (en) * 1978-06-26 1982-05-11 Haggar Theodore Self-contained valved package
US4335815A (en) * 1979-09-26 1982-06-22 Societe Nouvelle De Bouchons Plastiques Flexible package for storing and dispensing liquid or pasty matters
US4384440A (en) * 1979-11-09 1983-05-24 Tetra Pak Developpement Sa Method for the continuous manufacture of packing containers
US4502616A (en) * 1982-01-04 1985-03-05 Health Care Concepts, Inc. Single use vial
US4576284A (en) * 1983-12-02 1986-03-18 Warner-Lambert Company Closing of filled capsules
US4627538A (en) * 1985-03-25 1986-12-09 Kafkis Nick H Vessel closures and method of forming the closures
US4917267A (en) * 1986-11-12 1990-04-17 Laverdure Roland J A Self-closing valve with tamper evident lip seal tab for liquids, pastes or solids
US4988016A (en) * 1989-01-30 1991-01-29 James P. Hawkins Self-sealing container
US5035348A (en) * 1989-09-01 1991-07-30 Institute Guilfoyle Container having a pressure-rupturable seal for dispensing contents
US5100028A (en) * 1989-09-01 1992-03-31 Institute Guilfoyle Pressure-rupturable container seal having a fluid flow directing shield
US5577636A (en) * 1994-06-10 1996-11-26 Yoshida Kogyo Co., Ltd. Multi-tube container having breakable connections at both ends thereof
FR2738224A1 (fr) * 1994-06-10 1997-03-07 Yoshida Kogyo Kk Recipient multitube et procede de fabrication de celui-ci
ES2134099A1 (es) * 1996-05-08 1999-09-16 Laguna Vicente Gomez Pala removedora con contenedor.
US6247617B1 (en) 1999-12-13 2001-06-19 Richard Allen Clyde Single use container for dispensing separately housed sterile compositions
US6434913B1 (en) * 2000-09-15 2002-08-20 Thomas Hatch Single-use syringe
US20050257498A1 (en) * 2004-05-18 2005-11-24 Garry Tsaur Tube filling process for liquid filled cotton swabs
US20060042990A1 (en) * 2004-08-24 2006-03-02 Galuten Jerry H Medication kit
WO2006067206A1 (fr) * 2004-12-23 2006-06-29 Eurocolori Srl Systeme et procede permettant de colorer des peintures et revetements decoratifs, ainsi que dispositif d'actionnement relatif
US20060194710A1 (en) * 2003-02-03 2006-08-31 Reckitt Benckiser N.V. Emanator blister
US20080170814A1 (en) * 2006-12-18 2008-07-17 Cadbury Adams Usa Llc Resealable packaging
US20120312709A1 (en) * 2011-04-12 2012-12-13 Velcera, Inc. Device for storing and dispensing a medicament, and packaging for containing the same
US20130015204A1 (en) * 2009-12-24 2013-01-17 Arash Gol Single-use containers and uses thereof
US20130098864A1 (en) * 2010-07-26 2013-04-25 Lameplast S.P.A. Re-closable container for fluid products, particularly for medical, pharmaceutical and cosmetic products
WO2014011880A1 (fr) * 2012-07-12 2014-01-16 Colgate-Palmolive Company Emballage comportant un corps unitaire comprenant un bouchon autocassable
WO2014011874A1 (fr) * 2012-07-12 2014-01-16 Colgate-Palmolive Company Emballage comportant un corps unitaire comprenant un bouchon autocassable
US20150209228A1 (en) * 2014-01-30 2015-07-30 Merle Bruce Squeezable Ampule with Breakable Seal in Nose Bleed Kit
EP2909096A4 (fr) * 2012-07-27 2016-06-29 Diana Foster Emballage de distributeur à usage unique
US20160376139A1 (en) * 2014-07-22 2016-12-29 BIBO Barmaid LLC Cold beverage dispenser and flexible pouch
US20170197069A1 (en) * 2014-07-22 2017-07-13 Bayer Animal Health Gmbh Tube with application tip
US9932218B2 (en) 2016-03-04 2018-04-03 BIBO Barmaid LLC Cold beverage dispenser and cutter assembly for cold beverage dispenser
US20180312309A1 (en) * 2017-04-26 2018-11-01 The Hartz Mountain Corporation Applicator with Breakaway Cap
USD836001S1 (en) 2016-03-04 2018-12-18 Discovery Inc. Bar code for a pouch
USD840247S1 (en) 2016-03-04 2019-02-12 BIBO Barmaid LLC Pouch
US10898438B2 (en) 2014-05-20 2021-01-26 R.P. Scherer Technologies, Llc Capsule dispensing container
US11072521B2 (en) 2014-07-22 2021-07-27 BIBO Barmaid LLC Cold beverage dispenser
US20210331850A1 (en) * 2018-08-20 2021-10-28 Easysnap Technology S.R.L. Sealed Break-Open Package and Corresponding Method for the Production Thereof

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2516724A (en) * 1946-08-23 1950-07-25 Rossinov Michael Michaelovitch Wide angle orthoscopic anastigmatic photographic objective
DE957159C (de) * 1952-11-29 1957-01-31 Charles Nicolle Verfahren und Vorrichtung zur Verpackung von spritzbaren Produkten
DE1139942B (de) * 1954-04-07 1962-11-22 Merz & Co Salbenbehaelter mit Injektionsrohr
NL283761A (fr) * 1958-06-04
US3221939A (en) * 1962-01-08 1965-12-07 Barnes Hind International Inc Disposable dispensers
DE3435796A1 (de) * 1983-09-30 1985-04-11 Honda Giken Kogyo K.K., Tokio/Tokyo Elektrolyt-behaelter fuer eine batterie und verfahren zum einfuellen von elektrolyt

Citations (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1266413A (en) * 1917-06-26 1918-05-14 Armistead C Crump Paste-tube.
US1592584A (en) * 1924-06-13 1926-07-13 Viegelmann Robert Collapsible container
US1607626A (en) * 1922-02-06 1926-11-23 Gen Rubber Co Latex-shipping bale
US1742809A (en) * 1928-10-02 1930-01-07 Ros P Hoover Dispensing container for liquid medicine
US2005642A (en) * 1934-06-04 1935-06-18 Harry A Thornton Combined closing and outlet cap for collapsible tubes
US2028112A (en) * 1931-09-04 1936-01-14 Stokes Machine Co Hermetic closure for collapsible tubes
US2217336A (en) * 1937-08-14 1940-10-08 Elmer L Schumacher Means and process of making containers
US2279505A (en) * 1939-07-10 1942-04-14 Abbott Lab Capsule making machine
US2288327A (en) * 1935-10-08 1942-06-30 Robert P Scherer Apparatus for forming and filling capsules
US2297375A (en) * 1936-12-03 1942-09-29 Clarence W Vogt Container
US2397051A (en) * 1941-08-25 1946-03-19 Gelatin Products Corp Capsule
GB577189A (en) * 1943-12-17 1946-05-08 George Burdett Raper Improvements in or relating to capsules
US2401617A (en) * 1943-07-08 1946-06-04 Gelatin Products Corp Capsule structure
US2430995A (en) * 1942-12-31 1947-11-18 Roos William Lawrence End-sealed thermoplastic container body
US2446308A (en) * 1942-05-25 1948-08-03 Louis B Smith Package
US2469975A (en) * 1946-11-07 1949-05-10 Westinghouse Electric Corp Method for charging individual capsules with a compressed gas
US2530400A (en) * 1945-09-19 1950-11-21 Rado Leopold Process for the production of containers filled with liquids or pastes
US2552870A (en) * 1948-11-13 1951-05-15 Scherer Corp R P Sealed tube with finger-engaging opening tabs

Patent Citations (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1266413A (en) * 1917-06-26 1918-05-14 Armistead C Crump Paste-tube.
US1607626A (en) * 1922-02-06 1926-11-23 Gen Rubber Co Latex-shipping bale
US1592584A (en) * 1924-06-13 1926-07-13 Viegelmann Robert Collapsible container
US1742809A (en) * 1928-10-02 1930-01-07 Ros P Hoover Dispensing container for liquid medicine
US2028112A (en) * 1931-09-04 1936-01-14 Stokes Machine Co Hermetic closure for collapsible tubes
US2005642A (en) * 1934-06-04 1935-06-18 Harry A Thornton Combined closing and outlet cap for collapsible tubes
US2288327A (en) * 1935-10-08 1942-06-30 Robert P Scherer Apparatus for forming and filling capsules
US2297375A (en) * 1936-12-03 1942-09-29 Clarence W Vogt Container
US2217336A (en) * 1937-08-14 1940-10-08 Elmer L Schumacher Means and process of making containers
US2279505A (en) * 1939-07-10 1942-04-14 Abbott Lab Capsule making machine
US2397051A (en) * 1941-08-25 1946-03-19 Gelatin Products Corp Capsule
US2446308A (en) * 1942-05-25 1948-08-03 Louis B Smith Package
US2430995A (en) * 1942-12-31 1947-11-18 Roos William Lawrence End-sealed thermoplastic container body
US2401617A (en) * 1943-07-08 1946-06-04 Gelatin Products Corp Capsule structure
GB577189A (en) * 1943-12-17 1946-05-08 George Burdett Raper Improvements in or relating to capsules
US2530400A (en) * 1945-09-19 1950-11-21 Rado Leopold Process for the production of containers filled with liquids or pastes
US2469975A (en) * 1946-11-07 1949-05-10 Westinghouse Electric Corp Method for charging individual capsules with a compressed gas
US2552870A (en) * 1948-11-13 1951-05-15 Scherer Corp R P Sealed tube with finger-engaging opening tabs

Cited By (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2970723A (en) * 1952-12-16 1961-02-07 Flax Valer Manufacture of collapsible tubular container made of flexible materials
US2802608A (en) * 1954-10-18 1957-08-13 Joseph A Hull Sealed valve dispensing device
US2792149A (en) * 1954-10-28 1957-05-14 Joseph M Lutz Collapsible capless tube for toothpaste or the like
US2808926A (en) * 1954-11-10 1957-10-08 Blair M Drake Single dose vial assembly of animal semen
US3171412A (en) * 1956-06-15 1965-03-02 Brann Bernd Container for biological liquids
US2861572A (en) * 1957-04-09 1958-11-25 Barnes Hind Lab Inc Medicament dispenser
US2944706A (en) * 1957-04-29 1960-07-12 Alfred A Moore Collapsible container and dispensing holder therefor
US2908601A (en) * 1957-05-16 1959-10-13 Unette Corp Manufacture of internal pressure-rupturable seal in thermoplastic tubing
US2947448A (en) * 1957-07-23 1960-08-02 Duane C Maddux Collapsible tube closure and sealing means
US2875762A (en) * 1957-09-17 1959-03-03 Jr Carl W Middleton Suppository holder
US2962192A (en) * 1958-09-10 1960-11-29 Ivers Lee Co Package for fluent commodities
US3075528A (en) * 1958-11-26 1963-01-29 Astra Ab Laminated hypodermic syringe ampul
US3152727A (en) * 1961-09-26 1964-10-13 Mayer & Co Inc O Reclosable dispensing package
US3156383A (en) * 1962-04-05 1964-11-10 Maison Ind Tecnico Chimiche Ne Expansible single use dispensing container
US3234069A (en) * 1962-10-09 1966-02-08 Szasz Frank Package manufacturing apparatus
US3189227A (en) * 1962-12-07 1965-06-15 American Home Prod Fluid dispenser
US3178065A (en) * 1963-01-22 1965-04-13 Tubed Chemicals Corp Impermeable collapsible tube
US3221942A (en) * 1963-07-25 1965-12-07 Polaroid Corp Collapsible fluid container
US3184121A (en) * 1963-08-01 1965-05-18 Ivers Lee Co Package with self sealing closure
US3306567A (en) * 1964-08-20 1967-02-28 Gen Motors Corp Flexible bag for making ice cubes
US3338794A (en) * 1964-11-23 1967-08-29 Swift & Co Culturing anaerobic bacteria
US3308940A (en) * 1965-08-11 1967-03-14 Jr Theodore Morris Clinical thermometer device
US3463358A (en) * 1968-01-11 1969-08-26 Roy F Wenzler Material spreader means
US3523628A (en) * 1968-01-18 1970-08-11 Lee B Colvin Container for cyanoacrylate adhesive
US3652174A (en) * 1968-03-25 1972-03-28 Philip Boone Hermetically-sealed products and related method for cleansing and other uses
US3917120A (en) * 1971-11-11 1975-11-04 Merck Patent Gmbh Single use container for liquid pharmaceutical compositions
US3815794A (en) * 1972-03-02 1974-06-11 R Carlisle Plastic-film containers with self-sealing orifices
US3989045A (en) * 1972-09-29 1976-11-02 Eck William F Van Hypodermic syringe
US3971376A (en) * 1973-02-26 1976-07-27 Ceskoslovenska Akademie Ved Method and apparatus for introducing fluids into the body
US4159077A (en) * 1976-12-09 1979-06-26 W. R. Grace & Co. Process for closing a flexible container and the container formed thereby
US4135883A (en) * 1977-08-29 1979-01-23 Bio-Dynamics Inc. Blood analyzer system
US4328912A (en) * 1978-06-26 1982-05-11 Haggar Theodore Self-contained valved package
US4252257A (en) * 1978-10-10 1981-02-24 Herzig Albert M Automatic closure for containers having a pinch-off fold
US4335815A (en) * 1979-09-26 1982-06-22 Societe Nouvelle De Bouchons Plastiques Flexible package for storing and dispensing liquid or pasty matters
US4384440A (en) * 1979-11-09 1983-05-24 Tetra Pak Developpement Sa Method for the continuous manufacture of packing containers
US4502616A (en) * 1982-01-04 1985-03-05 Health Care Concepts, Inc. Single use vial
US4576284A (en) * 1983-12-02 1986-03-18 Warner-Lambert Company Closing of filled capsules
US4627538A (en) * 1985-03-25 1986-12-09 Kafkis Nick H Vessel closures and method of forming the closures
US4917267A (en) * 1986-11-12 1990-04-17 Laverdure Roland J A Self-closing valve with tamper evident lip seal tab for liquids, pastes or solids
US4988016A (en) * 1989-01-30 1991-01-29 James P. Hawkins Self-sealing container
US5035348A (en) * 1989-09-01 1991-07-30 Institute Guilfoyle Container having a pressure-rupturable seal for dispensing contents
US5100028A (en) * 1989-09-01 1992-03-31 Institute Guilfoyle Pressure-rupturable container seal having a fluid flow directing shield
US5577636A (en) * 1994-06-10 1996-11-26 Yoshida Kogyo Co., Ltd. Multi-tube container having breakable connections at both ends thereof
FR2738224A1 (fr) * 1994-06-10 1997-03-07 Yoshida Kogyo Kk Recipient multitube et procede de fabrication de celui-ci
ES2134099A1 (es) * 1996-05-08 1999-09-16 Laguna Vicente Gomez Pala removedora con contenedor.
US6247617B1 (en) 1999-12-13 2001-06-19 Richard Allen Clyde Single use container for dispensing separately housed sterile compositions
US6434913B1 (en) * 2000-09-15 2002-08-20 Thomas Hatch Single-use syringe
US8273696B2 (en) * 2003-02-03 2012-09-25 Reckitt Benckiser N.V. Emanator blister
US20060194710A1 (en) * 2003-02-03 2006-08-31 Reckitt Benckiser N.V. Emanator blister
US20050257498A1 (en) * 2004-05-18 2005-11-24 Garry Tsaur Tube filling process for liquid filled cotton swabs
US9085378B2 (en) * 2004-05-18 2015-07-21 Unidose Systems, Inc. Tube filling process for liquid filled cotton swabs
US20060042990A1 (en) * 2004-08-24 2006-03-02 Galuten Jerry H Medication kit
WO2006067206A1 (fr) * 2004-12-23 2006-06-29 Eurocolori Srl Systeme et procede permettant de colorer des peintures et revetements decoratifs, ainsi que dispositif d'actionnement relatif
US20080170814A1 (en) * 2006-12-18 2008-07-17 Cadbury Adams Usa Llc Resealable packaging
US8485728B2 (en) 2006-12-18 2013-07-16 Kraft Foods Global, Inc. Resealable packaging
US20130015204A1 (en) * 2009-12-24 2013-01-17 Arash Gol Single-use containers and uses thereof
US8833576B2 (en) * 2010-07-26 2014-09-16 Lameplast S.P.A. Re-closable container for fluid products, particularly for medical, pharmaceutical and cosmetic products
US20130098864A1 (en) * 2010-07-26 2013-04-25 Lameplast S.P.A. Re-closable container for fluid products, particularly for medical, pharmaceutical and cosmetic products
US20120312709A1 (en) * 2011-04-12 2012-12-13 Velcera, Inc. Device for storing and dispensing a medicament, and packaging for containing the same
US9376248B2 (en) 2012-07-12 2016-06-28 Colgate-Palmolive Company Package having unitary body including a break-off cap
CN104428207A (zh) * 2012-07-12 2015-03-18 高露洁-棕榄公司 具有包括断开帽的整体主体的包装
CN104428206A (zh) * 2012-07-12 2015-03-18 高露洁-棕榄公司 具有包括断开帽的整体主体的包装
AU2013290145B2 (en) * 2012-07-12 2015-06-04 Colgate-Palmolive Company Package having unitary body including a break-off cap
WO2014011880A1 (fr) * 2012-07-12 2014-01-16 Colgate-Palmolive Company Emballage comportant un corps unitaire comprenant un bouchon autocassable
US9908677B2 (en) 2012-07-12 2018-03-06 Colgate-Palmolive Company Package having unitary body including a break-off cap
CN104428207B (zh) * 2012-07-12 2016-10-19 高露洁-棕榄公司 具有包括断开帽的整体主体的包装
RU2607541C2 (ru) * 2012-07-12 2017-01-10 Колгейт-Палмолив Компани Упаковка, имеющая цельный корпус, включающий в себя отламывающийся колпачок
CN104428206B (zh) * 2012-07-12 2017-05-24 高露洁-棕榄公司 具有包括断开帽的整体主体的包装
WO2014011874A1 (fr) * 2012-07-12 2014-01-16 Colgate-Palmolive Company Emballage comportant un corps unitaire comprenant un bouchon autocassable
EP2909096A4 (fr) * 2012-07-27 2016-06-29 Diana Foster Emballage de distributeur à usage unique
US20150209228A1 (en) * 2014-01-30 2015-07-30 Merle Bruce Squeezable Ampule with Breakable Seal in Nose Bleed Kit
US10898438B2 (en) 2014-05-20 2021-01-26 R.P. Scherer Technologies, Llc Capsule dispensing container
US20170197069A1 (en) * 2014-07-22 2017-07-13 Bayer Animal Health Gmbh Tube with application tip
US10414642B2 (en) * 2014-07-22 2019-09-17 BIBO Barmaid LLC Cold beverage dispenser and flexible pouch
US20160376139A1 (en) * 2014-07-22 2016-12-29 BIBO Barmaid LLC Cold beverage dispenser and flexible pouch
US11072521B2 (en) 2014-07-22 2021-07-27 BIBO Barmaid LLC Cold beverage dispenser
US11672962B2 (en) * 2014-07-22 2023-06-13 Bayer Animal Health Gmbh Tube with application tip
US12017900B2 (en) * 2014-07-22 2024-06-25 BIBO Barmaid LLC Cold beverage dispenser and pouch
US9932218B2 (en) 2016-03-04 2018-04-03 BIBO Barmaid LLC Cold beverage dispenser and cutter assembly for cold beverage dispenser
USD836001S1 (en) 2016-03-04 2018-12-18 Discovery Inc. Bar code for a pouch
USD840247S1 (en) 2016-03-04 2019-02-12 BIBO Barmaid LLC Pouch
US11021360B2 (en) 2016-03-04 2021-06-01 BIBO Barmaid LLC Cold beverage dispenser and cutter assembly for cold beverage dispenser
US20180312309A1 (en) * 2017-04-26 2018-11-01 The Hartz Mountain Corporation Applicator with Breakaway Cap
US10179678B2 (en) * 2017-04-26 2019-01-15 The Hartz Mountain Corporation Applicator with breakaway cap
US20210331850A1 (en) * 2018-08-20 2021-10-28 Easysnap Technology S.R.L. Sealed Break-Open Package and Corresponding Method for the Production Thereof

Also Published As

Publication number Publication date
DE1677219U (de) 1954-06-03
FR1021004A (fr) 1953-02-13
CH294535A (fr) 1953-11-15
GB677592A (en) 1952-08-20
DE894609C (de) 1953-10-26
DK82541C (da) 1957-03-25

Similar Documents

Publication Publication Date Title
US2663461A (en) Container for pharmaceuticals and the like
US5244120A (en) Dual chamber medicament dispenser
US4963045A (en) Dispenser-applicator for spreading substances
US4266692A (en) Sealed container having a deformable elongate member in the seal area
US3986640A (en) Package for a flowable product and material for making such package
CA1301718C (fr) Emballage pour les produits comestibles extrudables
US9408455B2 (en) Container and valve assembly for storing and dispensing substances, and related method
US2720881A (en) Closure
SK6602002A3 (en) Reclosable dispenser package, reclosable outlet forming structure and method and apparatus for making same
EP0226290A2 (fr) Sachet distributeur et son procédé de fabrication
IT9022563A1 (it) Contenitore in laminato flessibile con inserto di apertura e richiusura.
AU2004200143A1 (en) Dispensing Sachet by Bending and Method of Sachet Manufacture
WO2007113066A1 (fr) sachet rempli de gaz
US8469240B2 (en) Dispensing fluids from containers using self closing valve, typically duckbill type valve
EP0721417A1 (fr) Procede et appareillage de production de sachets d'emballage
US20080108929A1 (en) Individual Dose Packaging
US3477614A (en) Dispenser
EP0690811B1 (fr) Sac ou poche destine(e) a contenir un fluide
JP2666961B2 (ja) 塗布物質用ディスペンサーアプリケーター
US3666145A (en) Collapsible dispenser with dispensing cap
US3178065A (en) Impermeable collapsible tube
JPH08230906A (ja) 押し出し容器及びその製造方法
EP0100796A1 (fr) Feuille en matière plastique avec zone présélectionnée de moindre résistance, procédé de fabrication et emballage fait à partir de cette feuille
JPH0671831A (ja) 良好な芳香障壁特性を有する積層パッケージ材料とその製造方法
DE19964027A1 (de) Packungseinheit