US20230372083A1 - Intraocular lens injector and its design method - Google Patents

Intraocular lens injector and its design method Download PDF

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Publication number
US20230372083A1
US20230372083A1 US18/044,235 US202118044235A US2023372083A1 US 20230372083 A1 US20230372083 A1 US 20230372083A1 US 202118044235 A US202118044235 A US 202118044235A US 2023372083 A1 US2023372083 A1 US 2023372083A1
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Prior art keywords
intraocular lens
protrusions
wall
tube
shape
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US18/044,235
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English (en)
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Kazunori Kudo
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Hoya Corp
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Hoya Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1662—Instruments for inserting intraocular lenses into the eye
    • A61F2/167—Instruments for inserting intraocular lenses into the eye with pushable plungers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1662—Instruments for inserting intraocular lenses into the eye
    • A61F2/1678—Instruments for inserting intraocular lenses into the eye with a separate cartridge or other lens setting part for storage of a lens, e.g. preloadable for shipping
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001—Designing or manufacturing processes

Definitions

  • the present disclosure relates to an intraocular lens injector and its design method.
  • Cataract surgery involves the removal of a cloudy crystalline lens by ultrasonic emulsification followed by implantation of an intraocular lens into an eye.
  • a soft intraocular lens made of a soft material such as silicone elastomer is injected into an eye using an intraocular lens injector.
  • the intraocular lens When a soft intraocular lens is injected into an eye, the intraocular lens can be folded to reduce the size of the corneal incision.
  • An example of a known method of folding an intraocular lens is to fold it within an intraocular lens injector.
  • Patent Documents 1 and 2 a plurality of protrusions are located on a top plate portion located in a passage through which the intraocular lens passes within the intraocular lens injector.
  • Patent Document 1 the optical portion of an intraocular lens is oriented within the body so that it is pressed against the bottom side of the passage, thereby reducing the risk that a support portion gets caught between the wall of the through-hole and the optical surface opposite to the surface on which the support portion is folded (paragraph 0005, paragraph 0023, claim 1, FIG. 4, etc. of the Patent Document 1).
  • Patent Document 2 a base part of the front support portion, which tends to lift up to a ceiling side when the optical portion is bent, can be pressed to a bottom side by a protruding portion (paragraphs 0051 to 0053, FIG. 5, etc. of Patent Document 2).
  • the present inventor has studied and found that when advancing the intraocular lens through a tube while folding the lens, and emitting the lens from a nozzle, the presence of both left and right corners at an upper side of an inner wall of the tube affects the success or failure of folding of the intraocular lens.
  • FIG. 1 is a schematic cross-sectional diagram illustrating an inner wall of a tube leading to a nozzle of an intraocular lens injector.
  • the reference numeral 10 designates the inner wall of the tube.
  • the reference numeral 41 indicates an optical portion of an intraocular lens.
  • FIG. 1 ( a ) is a diagram illustrating how the optical portion is normally folded into a valley-fold shape
  • FIG. 1 ( b ) to FIG. 1 ( d ) are diagrams illustrating how the optical portion can enter both left and right corners of the tube, forcing the lens to fold in an abnormal state.
  • FIG. 1 ( b ) is a diagram illustrating how a gap G is formed between the optical portion and a lower-side inner wall of the tube.
  • FIG. 1 ( c ) is a diagram illustrating how the optical portion is folded into a mountain-fold shape.
  • FIG. 1 ( d ) is a diagram illustrating how the optical portion is folded in a state of a non-uniform mixture of valley-fold shape and mountain-fold shape.
  • the optical portion can be in a state illustrated in FIG. 1 ( b ) or FIG. 1 ( d ) .
  • the support portion of the intraocular lens may enter the gap G formed by the optical portion.
  • FIG. 2 is a schematic cross-sectional diagram illustrating how protrusions are located at both left and right corners of the inner wall of the tube leading to the nozzle of the intraocular lens injector.
  • the reference numeral 15 designates the protrusion.
  • indication of the reference numerals of the tube and the protrusion will be omitted.
  • the optical portion can be folded into the valley-fold shape while its posture being corrected to the state illustrated in FIG. 1 ( a ) by adopting a shape of the inner wall (i.e., protrusion) such that neither the optical portion nor the support portion can enter both left and right corners at the upper side of the inner wall of the tube as illustrated in FIG. 2 .
  • a shape of the inner wall i.e., protrusion
  • a first aspect of the present disclosure provides
  • a seventh aspect of the present disclosure that is an aspect of any one of the first to sixth aspects, including:
  • An eighth aspect of the present disclosure that is an aspect of any one of the first to seventh aspects,
  • a ninth aspect of the present disclosure provides
  • aspects according to the design method of the intraocular lens injector may have the characteristics of each of the above aspects.
  • the protrusion may be located at a position where the cross-sectional shape of the inner wall has the largest rate of change in curvature.
  • the protrusions exist on the inner wall suitably within a range of 0 to 15 degrees, and even more suitably within a range of 10 to 15 degrees of the above-described inclination angle ⁇ .
  • a width w in the Y 1 -Y 2 direction of the protrusion (e.g., protrusion with stepped shape) located at the left corner is preferably 10 to 60% of a width W from a predetermined position of the vertical line formed by the midpoints of left and right (e.g., a midpoint O of up, down, left and right) to the left-hand inner wall.
  • the width in the Y 1 -Y 2 direction of the protrusion located at the left corner is set to 0.5 to 2.5 mm.
  • the same preferred examples may also be applied to the protrusion located at the right corner.
  • a height h in the Z 1 -Z 2 direction of the protrusion (e.g., protrusion with stepped shape) located at the left corner is preferably 30 to 80% of a height H between an upper-side inner wall and a lower-side inner wall on a vertical line passing through the above-described midpoint O of up, down, left and right.
  • the height in the Z 1 -Z 2 direction of the protrusion located at the left corner is set to 0.5 to 1.5 mm.
  • the same preferred examples may also be applied to the protrusion located at the right corner.
  • a protrusion at a position where the optical portion exists after the start of the folding of the intraocular lens.
  • the intraocular lens is installed in the lens installation portion, it is preferable to have a protrusion at least between the front end of the optical portion and the front end of the front support portion, the protrusion being preferably formed lengthwise in a front-back direction so as to include both the front ends.
  • Protrusions may be located on a lid of an injection cylinder main body, so that when the lid is closed, protrusions may be consequently formed at both the left and right corners in the tube.
  • a lower end of the protrusion may be displaced downward as it moves forward.
  • the length of the protrusion in the X 1 -X 2 direction is not limited as long as it is long enough to allow the tucking of the front support portion of the optical portion to be completed correctly when advancing the intraocular lens.
  • the length in the X 1 -X 2 direction of the protrusion located at the left corner is set to 5 to 15 mm.
  • the same preferred examples may also be applied to the protrusion located at the right corner.
  • a technique for folding an intraocular lens with high accuracy can be located.
  • FIG. 1 is a schematic cross-sectional diagram illustrating an inner wall of a tube leading to a nozzle of an intraocular lens injector.
  • FIG. 2 is a schematic cross-sectional diagram illustrating how protrusions are located at both left and right corners of the inner wall of the tube leading to the nozzle of the intraocular lens injector.
  • FIG. 3 is a perspective diagram illustrating a configuration example of an appearance of the intraocular lens injector.
  • FIG. 4 is a perspective diagram illustrating a structure and an arrangement of a tip portion of the injector main body.
  • FIG. 5 is a perspective diagram illustrating an intraocular lens injector case.
  • FIG. 6 is a perspective diagram illustrating how the intraocular lens injector is attached to the case.
  • FIG. 7 is a schematic cross-sectional diagram illustrating a modified example of the protrusion.
  • FIG. 8 A is a schematic cross-sectional diagram (Part 1) specifying the positional relationship of the protrusions.
  • FIG. 8 B is a schematic cross-sectional diagram (Part 2) specifying the positional relationship of the protrusions.
  • FIG. 8 C is a schematic cross-sectional diagram (Part 3) specifying the positional relationship of the protrusions.
  • FIG. 9 is a perspective diagram of another intraocular lens injector.
  • FIG. 10 is a cross-sectional diagram of another intraocular lens injector.
  • the middle panel is an X-Y cross-sectional diagram passing through a midpoint of up and down axis of the intraocular lens injector
  • a right panel is an X-Z cross-sectional diagram passing through the A-A line in the middle panel
  • left panels (a) to (f) are Y-Z cross-sectional diagrams.
  • FIG. 11 is a schematic cross-sectional diagram of an X-Z plane illustrating a positional relation between the front support portion and the tucking pin when advancing the intraocular lens.
  • one of the X axis directions is defined as X 1 direction and the other direction is defined as X 2 direction
  • one of the Y axis directions is defined as Y 1 direction and the other direction is defined as Y 2 direction
  • one of the Z axis directions is defined as Z 1 direction and the other direction is defined as Z 2 direction.
  • X 1 direction is defined as a tip end side (frontward, advancement direction of the lens)
  • X 2 direction is defined as a rear end side (rearward)
  • Y 1 direction is defined as a right side (rightward)
  • Y 2 direction is defined as a left side (leftward)
  • Z 1 direction is defined as an upper side (upward, thickness direction and a light axis direction when the intraocular lens is arranged)
  • Z 2 direction is defined as a downside (downward).
  • the X 1 direction and X 2 direction correspond to a length direction of the intraocular lens injector 1
  • the Y 1 direction and Y 2 direction correspond to a width direction of the intraocular lens injector
  • the Z 1 direction and Z 2 direction correspond to a height direction of the intraocular lens injector 1 .
  • This embodiment illustrates a preload type intraocular lens injector with the intraocular lens previously loaded therein, but the present disclosure is not limited thereto.
  • FIG. 3 is a perspective diagram illustrating a configuration example of an appearance of the intraocular lens injector according to an embodiment of the present disclosure.
  • FIG. 4 is a perspective diagram illustrating a structure and an arrangement of a tip portion of the injector main body according to an embodiment of the present disclosure.
  • the intraocular lens injector 1 is used for injecting an intraocular lens into an eye.
  • an one-piece type intraocular lens 4 (see FIG. 4 ) made of a soft material such as silicone elastomer or soft acrylic, which has an optical portion 41 including a circular effective optical portion 41 a which performs an optical function and its peripheral portion 41 b , as well as two support portions 42 a , 42 b that extend, curving outward from two positions on the outer circumferential portion of the optical portion 41 .
  • the reference numeral 42 a indicates a front support portion arranged frontward when installed in the lens installation portion 11
  • the reference numeral 42 b indicates a rear support portion arranged rearward.
  • optical portion 41 of the intraocular lens 4 and base end sides of the support portions 42 a , 42 b connected to the optical portion 41 are configured by a soft material.
  • This configuration facilitates folding of the intraocular lens 4 .
  • end sides of the support portions 42 a , 42 b may similarly be configured by the soft material, or may be configured by a hard material (e.g., polyethylene, PMMA).
  • An effective optical portion 41 a in the optical portion 41 has a shape that performs the optical function, a peripheral portion 41 b is formed in an annular shape around the effective optical portion 41 a , and the annular shape is like a flat plate.
  • the optical portion 41 may be configured only by the effective optical portion 41 a .
  • the peripheral portion 41 b may be formed continuously with the effective optical portion 41 a , that is, the peripheral portion 41 b and the effective optical portion 41 a may be smoothly connected to each other, forming a continuous surface.
  • the intraocular lens injector 1 has a configuration including an injector main body 5 , a slider 6 , an injection cylinder 7 , a rotary member 8 , a plunger 9 , and a rod 10 (located and concealed inside the intraocular lens injector 1 in FIG. 3 ).
  • each of these constituent elements is constituted by resin molded products.
  • the injector main body 5 and the injection cylinder 7 each have a hollow structure and are coupled to each other to thereby constitute a hollow body.
  • the present disclosure is remarkably characterized by a shape of the inner wall of the tube of the hollow body.
  • the slider 6 is attached to the injector main body 5 .
  • the intraocular lens 4 is advanced, and bent into a valley-fold shape (bent downward) along the narrowing inner diameter of the injection cylinder main body 7 a .
  • the bent intraocular lens 4 is advanced by the plunger 9 and thus the rod 10 , and discharged from the nozzle portion 7 b.
  • the injection cylinder 7 is arranged so as to communicate with a tip portion of the injector main body 5 .
  • the injection cylinder 7 and the tip portion of the injector main body 5 may be integrally molded, or may be separately molded and the injection cylinder 7 may be attached to the tip portion.
  • the injection cylinder 7 has a hollow injection cylinder main body 7 a and a narrow tubular nozzle portion 7 b.
  • the lens installation portion 11 of the injector main body 5 is accommodated and arranged, together with the intraocular lens 4 installed therein, inside the injection cylinder main body 7 a of the injection cylinder 7 .
  • An inlet 7 c is formed on a top surface of the injection cylinder main body 7 a .
  • the inlet 7 c is for injecting the viscoelastic substance (e.g., sodium hyaluronate).
  • the viscoelastic substance injected through the inlet 7 c is supplied to the intraocular lens 4 installed in the lens installation portion 11 .
  • the rotary member 8 is rotatably connected to a rear end portion of the injector main body 5 .
  • the plunger 9 is arranged coaxially with the injector main body 5 .
  • a part of the plunger 9 is arranged inside the injector main body 5 through the rotary member 8 , and the other part of the plunger 9 is arranged to protrude rearward from the rotary member 8 .
  • the rod 10 is arranged inside a hollow body consisting of the injector main body 5 and the injection cylinder 7 .
  • the rod 10 is connected to the plunger 9 , and plays a role in advancing the intraocular lens 4 .
  • the lens installation portion 11 includes a bottom surface portion 11 a , a lens receiving portion 11 b , and a lens guide portion 11 c .
  • the lens receiving portion 11 b receives and supports the intraocular lens 4 from below.
  • the intraocular lens 4 is installed in the lens installation portion 11 in a state in which the front support portion 42 a is arranged, as its name suggests, frontward (X 1 direction), and the other rear support portion 42 b is arranged, as its name suggests, rearward (X 2 direction).
  • the intraocular lens injector 1 is a preload type with the intraocular lens 4 is previously installed in the lens installation portion 11 of the injector main body 5 . Therefore, the intraocular lens 4 is one of the constituent elements of the intraocular lens injector 1 .
  • the intraocular lens injector is not necessarily required to be the preload type.
  • the configuration of the case for example, the configuration disclosed in Japanese Patent No. 5254669 by the present applicant may be adopted. Regarding the configuration of the case, for the contents not described below, the configuration described in Japanese Patent No. 5254669 can be applied, and the description of Japanese Patent No. 5254669 is incorporated herein as if fully set forth in the present specification.
  • the description in the above-described WO 2018/003854 differs from the description in the specification of Japanese Patent No. 5254669, the description in the above-described WO 2018/003854 shall prevail.
  • the specification of Japanese Patent No. 5254669 states that the intraocular lens 4 is installed in the lens installation portion with the front support portion bent by a protruding portion 80 , but in this embodiment, the position where the intraocular lens 4 is placed in its pre-bent state as described in WO 2018/003854 is regarded as the lens installation portion 11 .
  • FIG. 5 is a perspective diagram of the case of the intraocular lens injector according to an embodiment of the present disclosure.
  • FIG. 6 is a perspective diagram illustrating how the intraocular lens injector according to the embodiment of the present disclosure is attached to the case.
  • the intraocular lens injector 1 can be detachably attached to a case 62 which is integrally molded, for example, from a synthetic resin material.
  • the case 62 has a U-shaped wall portion 76 standing on a bottom plate portion 75 so as to surround the intraocular lens injector 1 , and a tucking pin 20 standing at a predetermined position on the bottom plate portion 75 .
  • the tucking pin 20 is configured so as to be injected into a protrusion injection hole 73 of the intraocular lens injector 1 when the intraocular lens injector 1 is attached to the case 62 , as shown in FIG. 11 of Japanese Patent No. 5254669 (corresponding to FIG. 6 of the present application).
  • the tucking pin 20 of the case 62 is arranged in the central region of the movable space of a tip member 71 .
  • the intraocular lens 4 placed in the lens installation portion 11 is advanced toward a discharge hole of the nozzle portion 7 b by the slider 6 .
  • this advancement may be made by the plunger 9 (directly by the rod 10 linked to the plunger 9 ). Therefore, the rod 10 linked to the slider 6 or the plunger 9 is also called an advancing member.
  • the intraocular lens 4 is bent into an approximate U-shape with the front support portion 42 a abutting the tucking pin 20 and a tip of the front support portion 42 a being folded backward (X 2 direction), in the opposite direction of a lens advancement direction (forward, X 1 direction).
  • the intraocular lens injector 1 can be detached from the case 62 while remaining in this state, and the intraocular lens 4 can be pushed forward (in X 1 direction) by the plunger 9 with the front support portion 42 a being bent, and the intraocular lens 4 can be injected into the eye through the nozzle portion 7 b.
  • the main feature of this embodiment is the protrusion located on both left and right corners on the inner wall in the tube through which the intraocular lens passes toward the nozzle.
  • the configuration of the known intraocular lens injector may be adopted.
  • the configuration of WO 2018/003854 by the present applicant may be adopted.
  • the configuration of the known intraocular lens injector (for example, the configuration of WO 2018/003854) shall be adopted, and the description of WO 2018/003854 is incorporated herein as if fully set forth in the present specification.
  • FIG. 3 and FIG. 4 of the present application are similar in configuration to FIG. 1 and FIG. 6 of WO 2018/003854, except for the intraocular lens 4 . Therefore, the reference numerals in FIG. 4 of the present application that are not described herein are as described in WO 2018/003854.
  • This embodiment is remarkably characterized by a shape of the inner wall of the tube in the intraocular lens injector.
  • the tube is formed by the injector main body and the injection cylinder that constitute the hollow structure.
  • the term “inner wall” used herein is a portion of the intraocular lens, forming an innermost contour of the tube that is a passage through which the intraocular lens passes in a cross-sectional view perpendicular to the advancement direction (the cross-sectional view on the Y-Z plane).
  • both the left and right corners at the upper side of the inner wall of the tube retain their concave shape, although protrusions are formed downward from the top plate portion.
  • the inner wall at the left corner indicated by the reference numeral 42 on the left side and the inner wall at the right corner indicated by the reference numeral 44 on the right side retains a concave shape (convex toward the outside of the tube).
  • the protrusions are located at both left and right corners at an upper side of the inner wall of the tube in a cross-sectional view perpendicular to the advancement direction of the intraocular lens (in a cross-sectional view on the Y-Z plane).
  • the description of the inner wall of the tube is based on the cross-sectional view (the cross-sectional view on the Y-Z plane) unless otherwise specified.
  • this configuration is based on the new finding that the incursion of the optical portion or the support portion into both the left and right corners affects the folding accuracy.
  • the shape in the cross-sectional view before the protrusions of this embodiment are formed is an elliptical shape with a major axis in Y 1 -Y 2 and a minor axis in Z 1 -Z 2 , as shown in FIG. 2 .
  • FIG. 7 is a schematic cross-sectional diagram illustrating a modified example of the protrusion.
  • Both the left and right corners in this embodiment refer to the vicinity of both the left and right corners (vicinity of CR, CL in FIG. 2 ) in a virtual cross-sectional contour formed by continuously changing the curvature between both ends of the protrusion in FIG. 2 .
  • both the left and right corners refer to the vicinity of both the left and right corners (vicinity of CR, CL in FIG. 2 ) in an actual cross-sectional contour.
  • the protrusion is a portion where the curvature changes sharply at a base portion of the protrusion.
  • a state where the curvature of the base portion of the protrusion is 10 times or more greater than the curvature of the vicinity of the base portion of the protrusion i.e., the shape of the inner diameter of the tube in the vicinity of the protrusion
  • a position where the curvature changes discontinuously from the curvature of the vicinity of the base of the protrusion may be considered as the base of the protrusion.
  • the area wherein the optical portion and the support portion can move can be reduced.
  • the optical portion can be folded into the valley-fold shape with its posture corrected to the state shown in FIG. 1 ( a ) , and both of the front support portion and the rear support portion can be tucked into the optical portion, and thus the intraocular lens can be folded with high accuracy.
  • the number of the protrusions there may be one for each of both the left and right corners (two in total) as shown in FIG. 2 , or there may be one for each of both the left and right corners, with one protruding downward and the other protruding inward horizontally ( FIG. 7 ( a ) ). Both the left and right corners may have a different number of protrusions ( FIG. 7 ( b ) ). For example, it is not precluded to provide more than one protrusion properly spaced so as to not to tuck the optical portion nor the support portion there between ( FIG. 7 ( c ) ).
  • the material of the protrusion is the same as those used for the injector main body and the hollow body which is an injection cylinder formed by injection molding, which is preferable. However, different material may be acceptable.
  • a space e.g., reference sign S in FIG. 2
  • a space is formed between both the left and right corners, having a width in which the folded support portions can be accommodated, due to the protrusions.
  • the front support portion and the rear support portion extend from the optical portion, in the intraocular lens.
  • the rear support portion is bent so as to be placed over the optical portion, and then the intraocular lens is advanced.
  • bending the support portion so as to be placed over the optical portion is referred to as “tucking”.
  • the rear support portion In a case where the rear support portion is tucked in advance, when a space S is formed between both the left and right corners, having a width in which the folded support portions can be accommodated, the rear support portion is accommodated in the space S upon advancement of the intraocular lens. Without the space S, the tucked rear support portion comes into contact with the left and right protrusions. When the intraocular lens advances while maintaining the contact, the tucking may be released due to friction caused by the left and right protrusions. This space S can reduce the possibility of the event occurring.
  • the tip portion of the slider may be accommodated in the space S described in the above paragraph.
  • the protrusions preferably protrude inward horizontally and also protrude downward at both the left and right corners, as shown in FIG. 2 . This configuration ensures that neither the optical portion nor the support portion can enter both the left and right corners.
  • the protrusion described in the previous paragraph is a protrusion of the stepped shape as shown in FIG. 2 , and it is preferred in that it ensures neither the optical portion nor the support portion can enter both the left and right corners.
  • the protrusion of the stepped shape may have rounded steps so long as the posture of the optical portion is corrected.
  • FIG. 8 A to FIG. 8 C are schematic cross-sectional diagrams (Part 1 to Part 3) for explaining a method of specifying the positional relation of the protrusions.
  • the cross-sectional shape of the inner wall of the tube without protrusions is provided. Then, a horizontal line L passing through a point O, a midpoint of up, down, left and right of the shape, is assumed.
  • a horizontal line L passing through a point O, a midpoint of up, down, left and right of the shape, is assumed.
  • the direction from the inner wall toward the point O is referred to as inside, and the opposite side is referred to as outside.
  • the protrusion preferably exists on the inner wall with the inclination angle ⁇ within any of a range of 0 to 20 degrees (preferably 0 to 15 degrees, more preferably 10 to 15 degrees) from this horizontal line.
  • the inner wall within entire or any of a range of 0 to 20 degrees of the inclination angle ⁇ may be set as both the left and right corners at the upper side.
  • the present invention does not preclude the protrusion existing on the inner wall within a range of less than 0 degrees or more than 20 degrees of ⁇ .
  • a minimum value of the inclination angle ⁇ in the part where the protrusions exist is preferably in a range of 0 to 15 degrees.
  • the starting position of the protrusion has the inclination angle ⁇ within a range from 0 to 15 degrees, and the protrusion is located continuously or discontinuously against the inner wall from the starting position as ⁇ increases.
  • the protrusions have a shape that changes a concave shape (protruding outward) of both the left and right corners to a convex shape (protruding inward) in the cross-sectional shape of the inner wall.
  • the protrusion may be located at a position where the cross-sectional shape of the inner wall has the largest rate of change in curvature.
  • a width w in the Y 1 -Y 2 direction of the protrusion (e.g., protrusion with stepped shape) located at the left corner is preferably 10 to 60% of a width W from a predetermined position on the vertical line formed of midpoints of left and right (e.g., a midpoint O of up, down, left and right) to the left inner wall.
  • the width in the Y 1 -Y 2 direction of the protrusion located at the left corner is set to 0.5 to 2.5 mm.
  • the same preferred examples may also be applied to the protrusion located at the right corner.
  • a height h in the Z 1 -Z 2 direction of the protrusion (e.g., protrusion with stepped shape) located at the left corner is preferably 30 to 80% of a height H between an upper-side inner wall and a lower-side inner wall on a vertical line passing through the above-described midpoint O of up, down, left and right.
  • the height in the Z 1 -Z 2 direction of the protrusion located at the left corner is set to 0.5 to 1.5 mm.
  • the same preferred examples may also be applied to the protrusion located at the right corner.
  • FIG. 9 is a perspective diagram of another intraocular lens injector.
  • FIG. 10 is a cross-sectional diagram of another intraocular lens injector.
  • a middle panel is an X-Y cross-sectional diagram passing through a midpoint of up and down of the intraocular lens injector
  • a right panel is an X-Z cross-sectional diagram passing through the A-A line in the middle panel
  • left panels (a) to (f) are Y-Z cross-sectional diagrams.
  • FIG. 3 to FIG. 6 so far described show the intraocular lens injector 1 using the slider 6
  • FIG. 9 and FIG. 10 show the intraocular lens injector 1 without the slider 6
  • a lid 7 d is located above the lens installation portion 11 .
  • the lid 7 d can be opened and closed.
  • FIG. 10 illustrates an example where protrusions 15 are located on a lid 7 d , so that when the lid 7 d is closed, the protrusions 15 may be consequently formed at both the left and right corners in the tube.
  • the arrangement of the protrusion e.g., protrusion with stepped shape
  • the protrusion is not limited as long as it allows for the tucking of the front support portion for the optical portion to be completed normally when advancing the intraocular lens. From the viewpoint of folding the intraocular lens 4 with high accuracy, it is preferable to locate the protrusion at a position that contributes to folding.
  • the protrusion it is preferable to locate the protrusion at the position where the optical portion 41 exists after the start of the folding of the intraocular lens 4 .
  • Putting “between (e) to (f)” in another way when the intraocular lens 4 is installed in the lens installation portion 11 , it is preferable to have a protrusion at least between the front end of the optical portion 41 and the front end of the front support portion 42 a , the protrusion being preferably formed lengthwise in a front-back direction and to include both the front ends.
  • the protrusion may be formed lengthwise between the position ( FIG. 10 ( a ) ) where the optical portion 41 does not exist at the start of the folding of the intraocular lens 4 and the front end of the front support portion 42 a.
  • protrusions may be located on a lid 7 d , so that when the lid 7 d is closed, protrusions may be consequently located at both the left and right corners in the tube.
  • the protrusion may be located on both the left and right corners on the inner wall of the tube in the injection cylinder main body 7 a.
  • a lower end of the protrusion may be displaced downward as it moves forward.
  • the intraocular lens 4 is installed in the lens installation portion 11 , it is preferable to displace the lower end of the protrusion downward as it moves forward, at least at the connection (e.g., a part extending from FIG. 10 ( a ) to FIG. 10 ( b ) ) with a rear support portion 42 b for the optical portion 41 , which helps proper tucking of the rear support portion 42 b.
  • the length of the protrusion in the X 1 -X 2 direction is not limited as long as it is long enough to allow the tucking of the front support portion for the optical portion to be completed normally when advancing the intraocular lens.
  • the length in the X 1 -X 2 direction of the protrusion located at the left corner is set to 5 to 15 mm.
  • the same preferred examples may also be applied to the protrusion located at the right corner.
  • the protruding portion 20 is configured so as to be injected into a protrusion injection hole 73 of the intraocular lens injector 1 when the intraocular lens injector 1 is attached to the case 62 , as shown in FIG. 5 and FIG. 6 .
  • the protruding portion 20 of the case 62 is arranged in the central region of the movable space of a tip member 71 .
  • the intraocular lens injector 1 With the intraocular lens injector 1 attached to the case 62 , the intraocular lens 4 placed in the lens installation portion 11 is advanced toward a discharge hole of the nozzle portion 7 b by the slider 6 .
  • the intraocular lens 4 is bent into an approximate U-shape with the front support portion 42 a abutting the protruding portion 20 and a tip of the front support portion 42 a being folded backward (X 2 direction), in the opposite direction of a lens advancement direction (forward, X 1 direction).
  • the protruding portion 20 is also referred to as the tucking pin 20 .
  • FIG. 11 is a schematic cross-sectional diagram of an X-Z plane illustrating a positional relation between the front support portion and the tucking pin when advancing the intraocular lens.
  • the tucking pin 20 preferably stands up upward and the surface that is in contact with the front support portion 42 a is a slope that slants upward towards the d front.
  • This configuration would facilitate the upward displacement of the front support portion after it contacts the tucking pin 20 .
  • the tucking pin having a rectangular shape as indicated by the reference numeral 80 in FIG. 10 of Japanese Patent No. 5254669 in place of this configuration, it tends to be uncertain whether the front support portion will be displaced upward or downward after coming into contact with the tucking pin.
  • An example in which the tucking pin has the above slope will be given below.
  • the protrusions are located at both the left and right corners of the inner wall at the upper side as described above. Therefore, neither the optical portion 41 nor the support portions 42 a , 42 b can enter both the left and right corners when the intraocular lens 4 is folded as it advances. This means that the optical portion 41 and the support portions 42 a , 42 b are naturally arranged nearer to the lower side.
  • the tucking pin 20 comes in contact with the front support portion 42 a ((2) in FIG. 11 which is this embodiment) at the timing earlier than that in the conventional front support portion shown by (1) in FIG. 11 . This reduces the risk of the front support portion 42 a entering between the outer surface, which is opposite to the inner surface, of the optical portion 41 , and the inner wall of the intraocular lens injector 1 during advancement of the intraocular lens.
  • the support portions 42 a , 42 b of the intraocular lens 4 tend to be lifted up from the viscoelastic material due to the difference in specific gravity from the viscoelastic material that passes through the tube together with the intraocular lens 4 .
  • both the optical portion 41 and the support portions 42 a , 42 b are naturally arranged nearer to the lower side.
  • the present inventor paid attention to the movement when the front support portion abuts against the protrusion portion described in the specification of Japanese Patent No. 5254669.
  • the protruding portion described in the specification of Japanese Patent No. 5254669 it is found that when the intraocular lens as a whole moves forward, the front support portion continues to bend backward and the timing of the tip of the front support portion moving to the vicinity of the inner wall of the intraocular lens injector tends to be very close to or earlier than the timing of the advancement of the periphery of the optical portion in the folded intraocular lens.
  • the present inventor created the technical idea that when the intraocular lens 4 as a whole advances, the tip of the front support portion 42 a , which is bending backward, is displaced more quickly than before so as to hasten the timing of the movement of the front support portion 42 a to the vicinity of the inner wall.
  • the optical portion 41 does not yet exist nearby when the front support portion 42 a moves to the vicinity of the inner wall.
  • the bending of the front support portion 42 a has progressed and the front support portion 42 a has already moved away from the vicinity of the inner wall.
  • the possibility of the front support portion 42 a being tucked between the optical portion 41 and the lower-side inner wall can be reduced.
  • the intraocular lens injector adopting the slider is exemplified, but the present invention can also be applied even when the intraocular lens is advanced only by the rod 10 (plunger 9 ) without using the slider.
  • the present disclosure can be applied with or without the slider and is highly versatile.
  • the present disclosure has technical significance as the design method of the intraocular lens injector as well.
  • the contents are as follows:
  • a design method of an intraocular lens injector that advances an intraocular lens including an optical portion with an optical function and a support portion that extends from the optical portion through a tube while folding the lens, and emits the lens from a nozzle, the method including:
  • the feature of the design method of the intraocular lens injector according to this embodiment resides in that the shape of the inner wall of the tube through which the intraocular lens passes is changed from the basic design before the design change.
  • the design method of the intraocular lens injector according to this embodiment would not need to change the cross-sectional shape of the inner wall of the tube except to provide the protrusion to both the left and right corners at the upper side of the inner wall of the tube as shown in FIG. 2 , for example, with respect to the basic design of the inner wall of the tube before design change (e.g. FIG. 1 ( a ) ).
  • the intraocular lens injector in which only difference between the shape of the inner wall of the tube before the design change and the shape of the inner wall of the tube after the design change is the protrusion described above can be considered to employ the design method of the intraocular lens injector according to this embodiment.
US18/044,235 2020-09-09 2021-08-30 Intraocular lens injector and its design method Pending US20230372083A1 (en)

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JP2020151086A JP7430128B2 (ja) 2020-09-09 2020-09-09 眼内レンズ挿入器具及びその設計方法
JP2020-151086 2020-09-09
PCT/JP2021/031663 WO2022054619A1 (ja) 2020-09-09 2021-08-30 眼内レンズ挿入器具及びその設計方法

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Cited By (1)

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Publication number Priority date Publication date Assignee Title
US11938019B2 (en) 2007-05-30 2024-03-26 Hoya Corporation Intraocular lens insertion device

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Publication number Priority date Publication date Assignee Title
JP4595136B2 (ja) 2005-05-31 2010-12-08 スター・ジャパン株式会社 眼内挿入用レンズの挿入器具
EP2161005B1 (en) 2007-05-30 2016-12-28 Hoya Corporation Intraocular lens inserting tool
JP5254669B2 (ja) 2008-06-05 2013-08-07 Ｈｏｙａ株式会社 眼内レンズ挿入器具及びカートリッジ
ES2549727T3 (es) 2009-10-22 2015-11-02 Kowa Company Ltd. Dispositivo de inserción de lentes intraoculares
JP5511530B2 (ja) 2010-06-10 2014-06-04 Ｈｏｙａ株式会社 眼内レンズ挿入装置
JP6458409B2 (ja) 2014-09-01 2019-01-30 株式会社ニデック 眼内レンズ挿入器具
JP6589338B2 (ja) 2015-03-31 2019-10-16 株式会社ニデック 眼内レンズ挿入器具
US11033382B2 (en) 2016-06-28 2021-06-15 Hoya Corporation Intraocular lens injector

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11938019B2 (en) 2007-05-30 2024-03-26 Hoya Corporation Intraocular lens insertion device

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WO2022054619A1 (ja) 2022-03-17
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EP4212128A1 (en) 2023-07-19
CN115867228A (zh) 2023-03-28

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