US20190133952A1 - Preparation method of sustained-release microparticles - Google Patents
Preparation method of sustained-release microparticles Download PDFInfo
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- US20190133952A1 US20190133952A1 US16/095,315 US201716095315A US2019133952A1 US 20190133952 A1 US20190133952 A1 US 20190133952A1 US 201716095315 A US201716095315 A US 201716095315A US 2019133952 A1 US2019133952 A1 US 2019133952A1
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- microparticles
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- drug
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
Definitions
- the solvent removal in step 4) may use the following method:
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CN201610269834.1A CN105963258B (zh) | 2016-04-26 | 2016-04-26 | 一种缓释微粒的制备方法 |
CN201610269834.1 | 2016-04-26 | ||
PCT/CN2017/081640 WO2017186077A1 (fr) | 2016-04-26 | 2017-04-24 | Procédé de préparation de microparticules à libération prolongée |
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EP (1) | EP3434263B1 (fr) |
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US11865213B2 (en) * | 2021-07-05 | 2024-01-09 | Mapi Pharma Ltd. | Semaglutide depot systems and use thereof |
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CN105963258B (zh) * | 2016-04-26 | 2021-01-22 | 广州帝奇医药技术有限公司 | 一种缓释微粒的制备方法 |
US11612563B2 (en) | 2017-07-17 | 2023-03-28 | Medincell | Pharmaceutical composition |
US20210154147A1 (en) * | 2018-10-19 | 2021-05-27 | Ac Pharmaceuticals Co., Ltd. | Preparation method of sustained-release microparticles |
CN110498919B (zh) * | 2019-07-26 | 2022-03-01 | 河南师范大学 | 一种酯化度可控的γ-PGA-Bn的合成方法 |
CN111150883A (zh) * | 2020-01-14 | 2020-05-15 | 北京四环制药有限公司 | 可生物降解的注射填充物及其制备方法和其应用 |
KR20220032301A (ko) * | 2020-09-07 | 2022-03-15 | (주)인벤티지랩 | 약물의 지속 방출을 위한 서방형 마이크로입자 |
CN112354010A (zh) * | 2020-11-27 | 2021-02-12 | 曲阜师范大学 | 一种聚γ-谷氨酸/壳聚糖/柠檬酸钙生物材料及其制备方法 |
CN112603892B (zh) * | 2020-12-18 | 2023-09-05 | 中国药科大学 | 一种载药微球及其制备方法 |
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CN105963258B (zh) * | 2016-04-26 | 2021-01-22 | 广州帝奇医药技术有限公司 | 一种缓释微粒的制备方法 |
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- 2016-04-26 CN CN201610269834.1A patent/CN105963258B/zh active Active
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2017
- 2017-04-24 US US16/095,315 patent/US20190133952A1/en active Pending
- 2017-04-24 EP EP17788729.6A patent/EP3434263B1/fr active Active
- 2017-04-24 WO PCT/CN2017/081640 patent/WO2017186077A1/fr active Application Filing
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EP3434263A1 (fr) | 2019-01-30 |
EP3434263A4 (fr) | 2019-03-27 |
CN105963258B (zh) | 2021-01-22 |
EP3434263B1 (fr) | 2020-07-15 |
WO2017186077A1 (fr) | 2017-11-02 |
CN105963258A (zh) | 2016-09-28 |
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