US20170216019A1 - Phakic intraocular lens - Google Patents

Phakic intraocular lens Download PDF

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Publication number
US20170216019A1
US20170216019A1 US15/329,140 US201415329140A US2017216019A1 US 20170216019 A1 US20170216019 A1 US 20170216019A1 US 201415329140 A US201415329140 A US 201415329140A US 2017216019 A1 US2017216019 A1 US 2017216019A1
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United States
Prior art keywords
diffraction grating
intraocular lens
phakic intraocular
grooves
center
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US15/329,140
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English (en)
Inventor
Kimiya Shimizu
Kazuhiko Onuma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Musashino Lens Research Inc
Original Assignee
Musashino Lens Research Inc
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Filing date
Publication date
Application filed by Musashino Lens Research Inc filed Critical Musashino Lens Research Inc
Assigned to Musashino Lens Research, Inc. reassignment Musashino Lens Research, Inc. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SHIMIZU, KIMIYA, ONUMA, KAZUHIKO
Publication of US20170216019A1 publication Critical patent/US20170216019A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1602—Corrective lenses for use in addition to the natural lenses of the eyes or for pseudo-phakic eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1601—Lens body having features to facilitate aqueous fluid flow across the intraocular lens, e.g. for pressure equalization or nutrient delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1602—Corrective lenses for use in addition to the natural lenses of the eyes or for pseudo-phakic eyes
    • A61F2/161—Posterior chamber lenses for use in addition to the natural lenses of the eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1654—Diffractive lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0053—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in optical properties

Definitions

  • the present invention relates a phakic intraocular lens with a diffraction grating.
  • a phakic intraocular lens is recognized as a way of correcting visual impairment, besides eyeglasses and contact lenses.
  • a lens for implantation between the iris and the crystalline lens is known as this phakic intraocular lens.
  • a phakic intraocular lens described in Patent Literature 1 includes a central optic part, a peripheral haptic part, and a penetrating hole having an anterior orifice and a posterior orifice, and the groove is arranged at the border of, or outside, the central optic part.
  • Patent Literature 1 Japanese Translation of PCT International Application No. 2007-534360
  • a phakic intraocular lens is a convex lens
  • the central part of the lens is thick.
  • providing a hole in the central part of the convex lens impairs the optical performance of the lens.
  • the present invention aims to provide a phakic intraocular lens which allows reduction in lens thickness and facilitates the flow of aqueous humor.
  • a phakic intraocular lens according to the present invention is a phakic intraocular lens for implantation between an iris and a crystalline lens, comprising: a diffraction grating disposed in a central part of the lens, the diffraction grating having circular, coaxial grooves formed thereon; and a support part that is disposed outside the diffraction grating and supports the diffraction grating.
  • a hole is formed in a center of the diffraction grating.
  • FIG. 1 is a diagram showing the configuration of a phakic intraocular lens according to Embodiment 1 of the present invention.
  • FIG. 2 is a sectional side view of an eye having the phakic intraocular lens according to Embodiment 1 of the present invention.
  • FIG. 3 is a diagram schematically showing the configuration of a diffraction grating of the phakic intraocular lens according to Embodiment 1 of the present invention, the diffraction grating having grooves formed thereon.
  • FIG. 4 is a diagram illustrating a single focal point formed by the diffraction grating of the phakic intraocular lens according to Embodiment 1 of the present invention, the diffraction grating having serrated grooves formed thereon.
  • FIG. 5 is a diagram showing in detail the diffraction grating shown in FIG. 4 having the serrated grooves formed thereon.
  • FIG. 6 is a diagram illustrating two focal points formed by a diffraction grating of a conventional phakic intraocular lens having serrated grooves.
  • FIG. 7 is a diagram showing in detail the diffraction grating of the conventional phakic intraocular lens having the serrated grooves.
  • FIG. 8 is a diagram showing the configuration of a phakic intraocular lens according to Embodiment 2 of the present invention.
  • a phakic intraocular lens according to Embodiment 1 of the present invention is described in detail below with reference to the drawings.
  • FIG. 1 is a diagram showing the configuration of a phakic intraocular lens according to Embodiment 1 of the present invention.
  • a phakic intraocular lens 1 according to Embodiment 1 of the present invention is made from a copolymer of collagen, namely Collamer, and is implanted between the iris and the crystalline lens.
  • the phakic intraocular lens 1 includes: a diffraction grating 5 which is disposed in a lens central part 2 and has coaxial grooves formed thereon; and a support part 3 which is disposed outside the diffraction grating 5 and supports the diffraction grating 5 .
  • Reference numerals 4 a and 4 b indicate markings on the phakic intraocular lens, and they are provided outside the lens central part 2 .
  • a circular hole 6 is formed in the center of the diffraction grating 5 .
  • the hole 6 is 0.25 mm to 0.5 mm in diameter.
  • FIG. 2 is a sectional side view of an eye having the phakic intraocular lens according to Embodiment 1 of the present invention.
  • an eye 8 has a cornea 9 , a crystalline lens 10 , an iris 11 , an anterior chamber 13 , and a posterior chamber 14 .
  • the phakic intraocular lens 1 is implanted between the iris 11 and the crystalline lens 10 .
  • a gap 12 is provided between the phakic intraocular lens 1 and the crystalline lens 10 .
  • Aqueous humor in the posterior chamber 14 flows into the anterior chamber 13 through the gap 12 and the hole 6 in the diffraction grating 5 .
  • FIG. 3 is a diagram schematically showing the configuration of the diffraction grating of the phakic intraocular lens according to Embodiment 1 of the present invention, the diffraction grating having grooves formed thereon.
  • FIG. 3 shows a basic configuration of a diffraction grating, and the grooves are shown as slits.
  • the diffraction grating 5 has circular, coaxial grooves 5 a to 5 d formed thereon.
  • the grooves 5 a to 5 d are formed such that the farther an interval between the grooves is from the center of the diffraction grating 5 , the smaller the interval is.
  • the interval between the groove 5 b and the groove 5 c is smaller than the interval between the groove 5 a and the groove 5 b
  • the interval between the groove 5 d and the groove 5 c is smaller than the interval between the groove 5 b and the groove 5 c.
  • a height h from the center O of the diffraction grating 5 to each of the circular, coaxial grooves 5 a to 5 d is expressed by Formula (1):
  • ⁇ is the wavelength of light
  • m is an integer
  • R is the distance between the center O of the diffraction grating 5 and a focal point P.
  • m is 1
  • the height h is the distance between the center O to the groove 5 a .
  • m is 2
  • the height h is the distance between the center O to the groove 5 b.
  • FIG. 4 is a diagram illustrating a single focal point formed by the diffraction grating of the phakic intraocular lens according to Embodiment 1 of the present invention, the diffraction grating having serrated grooves formed thereon.
  • FIG. 5 is a diagram showing in detail the diffraction grating shown in FIG. 4 having the serrated grooves formed thereon.
  • Serrated portions 5 A to 5 C are formed in the grooves to provide the diffraction grating 5 with a function as a lens.
  • the serrated portions 5 A to 5 C are formed circularly and coaxially, the serrated portion 5 B being narrower than the serrated portion 5 A, the serrated portion 5 C being narrower than the serrated portion 5 B.
  • the index of refraction of each of the serrated portions 5 A to 5 C is indicated by nL, and the index of refraction of an area other than the serrated portions 5 A to 5 C is indicated by nW.
  • the index of refraction nL is set to be larger than 1 to slow down the passage of light.
  • a height D is 4.4 ⁇ m when the wavelength ⁇ is 0.546 ⁇ m (e-line), nL is 1.46 (the index of refraction of the lens), and nW is 1.336 (the index of refraction of aqueous humor).
  • the height D of each of the serrated portions 5 A to 5 C is also 4.4 ⁇ m.
  • FIG. 6 is a diagram illustrating two focal points formed by a diffraction grating in a conventional phakic intraocular lens having serrated grooves formed thereon.
  • FIG. 7 is a diagram showing in detail the diffraction grating of the conventional phakic intraocular lens having the serrated grooves formed thereon.
  • serrated portions 5 - 1 to 5 - 3 are formed in the grooves.
  • the serrated portions 5 - 1 to 5 - 3 are formed such that not all the phases coincide, so that two focal points are obtained.
  • Parallel light beams reinforce each other, and light beams that superpose due to the reduced height D weaken each other in intensity.
  • the following Formula (3) for the height D holds true when the ratio of intensity between light distributed to one of the two focal points and light distributed to the other one focal point is 5:5:
  • the height D is 2.2 ⁇ m.
  • the height of each of the serrated portions 5 A to 5 C shown in FIG. 4 is D
  • the height of each of the serrated portions 5 - 1 to 5 - 3 shown in FIG. 6 is D/2.
  • the diffraction grating 5 functions as a convex lens, contributing reduction in the thickness of the phakic intraocular lens 1 .
  • the hole 6 can be easily formed in the center of the diffraction grating 5 which is formed in the lens central part 2 .
  • the diffraction grating 5 is thin, the optical performance of the phakic intraocular lens is not impaired.
  • aqueous humor can easily flow from the posterior chamber 14 to the anterior chamber 13 through the gap 12 and the hole 6 formed in the center of the diffraction grating 5 .
  • the phakic intraocular lens 1 according to Embodiment 1 thus facilitates the flow of aqueous humor.
  • the optical properties of the phakic intraocular lens 1 provided with the hole 6 are almost the same as those of a phakic intraocular lens without the hole 6 .
  • the diffraction grating 5 can form a single focal point because the diffraction grating 5 has the grooves which are formed such that the farther an interval between the grooves is from the center of the diffraction grating 5 , the smaller the interval is, the grooves being provided with the serrated portions 5 A to 5 C whose height D is adjusted to a predetermined value according to Formula (2).
  • the optical performance of the phakic intraocular lens is not impaired.
  • FIG. 8 is a diagram showing the configuration of a phakic intraocular lens according to Embodiment 2 of the present invention.
  • the phakic intraocular lens according to Embodiment 2 shown in FIG. 8 is characterized in that three holes 6 a, 6 b , and 6 c are provided near the center of the diffraction grating 5 .
  • the three holes 6 a, 6 b, and 6 c are provided within a 1.5-mm diameter circle whose center is the center of the diffraction grating 5 , and are each 0.1 mm in diameter.
  • the phakic intraocular lens having such three holes 6 a, 6 b, and 6 c near the center of the diffraction grating 5 can also achieve advantageous effects similar to those achieved by the phakic intraocular lens according to Embodiment 1.
  • three holes are provide within a 1.5-mm diameter circle whose center is the center of the diffraction grating 5 in Embodiment 2
  • two holes may be provided within a 1.5-mm diameter circle whose center is the center of the diffraction grating 5 . In such a case, the two holes are each 0.15 mm in diameter.
  • the sum of the areas of holes in the multiple-hole case needs to be equal to or smaller than the area of a hole in the single-hole case.
  • the present invention is applicable to an intraocular lens for implantation between the iris and the crystalline lens.

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  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Prostheses (AREA)
US15/329,140 2014-07-25 2014-07-25 Phakic intraocular lens Abandoned US20170216019A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2014/069742 WO2016013121A1 (ja) 2014-07-25 2014-07-25 有水晶体眼内レンズ

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2014/069742 A-371-Of-International WO2016013121A1 (ja) 2014-07-25 2014-07-25 有水晶体眼内レンズ

Related Child Applications (1)

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US16/204,946 Division US11166807B2 (en) 2014-07-25 2018-11-29 Phakic intraocular lens

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US16/204,946 Active 2035-05-16 US11166807B2 (en) 2014-07-25 2018-11-29 Phakic intraocular lens

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US (2) US20170216019A1 (es)
EP (1) EP3173050B1 (es)
JP (1) JP6263266B2 (es)
KR (1) KR101840612B1 (es)
CN (1) CN106659566B (es)
ES (1) ES2775599T3 (es)
RU (1) RU2650208C1 (es)
WO (1) WO2016013121A1 (es)

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WO2021152815A1 (ja) * 2020-01-31 2021-08-05 有限会社武蔵野レンズ研究所 有水晶体眼内レンズ

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US20080097599A1 (en) * 2006-10-19 2008-04-24 Rozakis George W Posterior chamber Phakic Intraocular Lens
US20110267693A1 (en) * 2009-01-06 2011-11-03 Menicon Co., Ltd. Method of manufacturing diffraction lens
US8623083B2 (en) * 2009-11-06 2014-01-07 Amo Groningen B.V. Diffractive binocular lens systems and methods

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US20040008551A1 (en) * 2002-01-07 2004-01-15 Mitsubishi Denki Kabushiki Kaisha Non-volatile semiconductor memory device
US20080097599A1 (en) * 2006-10-19 2008-04-24 Rozakis George W Posterior chamber Phakic Intraocular Lens
US20110267693A1 (en) * 2009-01-06 2011-11-03 Menicon Co., Ltd. Method of manufacturing diffraction lens
US8623083B2 (en) * 2009-11-06 2014-01-07 Amo Groningen B.V. Diffractive binocular lens systems and methods

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CN106659566A (zh) 2017-05-10
WO2016013121A1 (ja) 2016-01-28
EP3173050A4 (en) 2018-04-04
US11166807B2 (en) 2021-11-09
KR20170024009A (ko) 2017-03-06
RU2650208C1 (ru) 2018-04-11
ES2775599T3 (es) 2020-07-27
EP3173050B1 (en) 2020-02-19
US20190183634A1 (en) 2019-06-20
JPWO2016013121A1 (ja) 2017-04-27
KR101840612B1 (ko) 2018-03-20
EP3173050A1 (en) 2017-05-31
CN106659566B (zh) 2018-06-12
JP6263266B2 (ja) 2018-01-17

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