US20110243847A1 - Imaging diagnostics by combining contrast agents - Google Patents
Imaging diagnostics by combining contrast agents Download PDFInfo
- Publication number
- US20110243847A1 US20110243847A1 US12/666,205 US66620508A US2011243847A1 US 20110243847 A1 US20110243847 A1 US 20110243847A1 US 66620508 A US66620508 A US 66620508A US 2011243847 A1 US2011243847 A1 US 2011243847A1
- Authority
- US
- United States
- Prior art keywords
- eccm
- lscm
- contrast agent
- imaging
- diagnosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/48—Diagnostic techniques
- A61B6/481—Diagnostic techniques involving the use of contrast agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
- A61K49/105—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA the metal complex being Gd-DTPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/02—Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computerised tomographs
- A61B6/037—Emission tomography
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- High Energy & Nuclear Physics (AREA)
- Pathology (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07110922A EP2005970A1 (fr) | 2007-06-22 | 2007-06-22 | Imagerie Diagnostique par combinaison de moyens de contraste |
EP07110922.7 | 2007-06-22 | ||
PCT/EP2008/057886 WO2009000777A2 (fr) | 2007-06-22 | 2008-06-20 | Diagnostics d'imagerie par combinaison d'agents de contraste |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2008/057886 A-371-Of-International WO2009000777A2 (fr) | 2007-06-22 | 2008-06-20 | Diagnostics d'imagerie par combinaison d'agents de contraste |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/860,675 Division US9179882B2 (en) | 2007-06-22 | 2013-04-11 | Imaging diagnostics by combining contrast agents |
Publications (1)
Publication Number | Publication Date |
---|---|
US20110243847A1 true US20110243847A1 (en) | 2011-10-06 |
Family
ID=38627016
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/666,205 Abandoned US20110243847A1 (en) | 2007-06-22 | 2008-06-20 | Imaging diagnostics by combining contrast agents |
US13/860,675 Active US9179882B2 (en) | 2007-06-22 | 2013-04-11 | Imaging diagnostics by combining contrast agents |
US14/859,595 Active 2028-09-27 US9682159B2 (en) | 2007-06-22 | 2015-09-21 | Imaging diagnostics by combining contrast agents |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/860,675 Active US9179882B2 (en) | 2007-06-22 | 2013-04-11 | Imaging diagnostics by combining contrast agents |
US14/859,595 Active 2028-09-27 US9682159B2 (en) | 2007-06-22 | 2015-09-21 | Imaging diagnostics by combining contrast agents |
Country Status (10)
Country | Link |
---|---|
US (3) | US20110243847A1 (fr) |
EP (6) | EP2005970A1 (fr) |
CY (1) | CY1116213T1 (fr) |
DK (2) | DK2572735T3 (fr) |
ES (2) | ES2534970T3 (fr) |
HR (1) | HRP20150472T1 (fr) |
PL (2) | PL2170405T3 (fr) |
PT (1) | PT2572735E (fr) |
SI (2) | SI2170405T1 (fr) |
WO (1) | WO2009000777A2 (fr) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10032268B2 (en) | 2012-08-06 | 2018-07-24 | Koninklijke Philips N.V. | Dynamic contrast-enhanced imaging based permeability metric |
WO2020243585A1 (fr) * | 2019-05-29 | 2020-12-03 | Sicreations, Llc | Procédés de conservation d'un sujet et utilisation d'agents de contraste d'imagerie |
US11054534B1 (en) | 2020-04-24 | 2021-07-06 | Ronald Nutt | Time-resolved positron emission tomography encoder system for producing real-time, high resolution, three dimensional positron emission tomographic image without the necessity of performing image reconstruction |
US11300695B2 (en) | 2020-04-24 | 2022-04-12 | Ronald Nutt | Time-resolved positron emission tomography encoder system for producing event-by-event, real-time, high resolution, three-dimensional positron emission tomographic image without the necessity of performing image reconstruction |
CN115785468A (zh) * | 2022-11-21 | 2023-03-14 | 苏州大学 | 一种用于富集细胞外囊泡的zif-8-dspe材料及其制备方法和应用 |
US11730831B2 (en) | 2019-03-26 | 2023-08-22 | Sicreations, Llc | Imaging agents and methods of using the same |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2706373C1 (ru) * | 2019-03-01 | 2019-11-18 | Федеральное Государственное бюджетное образовательное учреждение высшего образования Дагестанский государственный медицинский университет Министерства здравоохранения Российской Федерации | Способ определения локализации опухолевой обструкции билиарного тракта и степени её распространенности |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
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US5059415A (en) * | 1989-02-21 | 1991-10-22 | The State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon Health | Method for diagnostically imaging lesions in the brain inside a blood-brain barrier |
US20020061279A1 (en) * | 2000-04-28 | 2002-05-23 | Degrado Timothy R. | 18F-labeled choline analogs |
US6490476B1 (en) * | 1999-10-14 | 2002-12-03 | Cti Pet Systems, Inc. | Combined PET and X-ray CT tomograph and method for using same |
US6972122B2 (en) * | 2001-01-05 | 2005-12-06 | Duke University | Contrast enhancement agent for magnetic resonance imaging |
US20080008366A1 (en) * | 2006-06-20 | 2008-01-10 | Vladimir Desh | Simultaneous visualization, analysis and navigation of multi-modality medical imaging data |
Family Cites Families (41)
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US4647447A (en) | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
US4444690A (en) | 1982-02-25 | 1984-04-24 | University Patents, Inc. | Technetium chelates |
US4673562A (en) | 1983-08-19 | 1987-06-16 | The Children's Medical Center Corporation | Bisamide bisthiol compounds useful for making technetium radiodiagnostic renal agents |
US4670545A (en) | 1984-05-11 | 1987-06-02 | University Patents, Inc. | Chelating agents for technetium-99M |
US4980147A (en) | 1984-06-25 | 1990-12-25 | University Of Utah Research Foundation | Radiolabeled technetium chelates for use in renal function determinations |
US4897255A (en) | 1985-01-14 | 1990-01-30 | Neorx Corporation | Metal radionuclide labeled proteins for diagnosis and therapy |
US4965392A (en) | 1987-03-26 | 1990-10-23 | Neorx Corporation | Chelating compounds for metal-radionuclide labeled proteins |
US5198208A (en) | 1987-07-16 | 1993-03-30 | Nycomed Imaging As | Aminopolycarboxylic acids and derivatives thereof |
US5021556A (en) | 1987-07-22 | 1991-06-04 | Neorx Corporation | Method of radiolabeling chelating compounds comprising sulfur atoms with metal radionuclides |
GB8808305D0 (en) | 1988-04-08 | 1988-05-11 | Nycomed As | Compositions |
US4988496A (en) | 1988-05-31 | 1991-01-29 | Neorx Corporation | Metal radionuclide chelating compounds for improved chelation kinetics |
US5075099A (en) | 1988-05-31 | 1991-12-24 | Neorx Corporation | Metal radionuclide chelating compounds for improved chelation kinetics |
US5364613A (en) | 1989-04-07 | 1994-11-15 | Sieving Paul F | Polychelants containing macrocyclic chelant moieties |
US5078985A (en) | 1989-08-09 | 1992-01-07 | Rhomed, Incorporated | Radiolabeling antibodies and other proteins with technetium or rhenium by regulated reduction |
JPH03228046A (ja) | 1989-09-13 | 1991-10-09 | Konica Corp | 赤外吸収染料を有し経時安定性に優れる写真材料 |
US5367080A (en) | 1990-11-08 | 1994-11-22 | Sterling Winthrop Inc. | Complexing agents and targeting radioactive immunoreagents useful in therapeutic and diagnostic imaging compositions and methods |
EP0664713B1 (fr) | 1992-10-14 | 2000-01-19 | Nycomed Imaging As | Procedes et compositions d'imagerie diagnostique et therapeutique |
US5756688A (en) | 1992-10-14 | 1998-05-26 | Sterling Winthrop Inc. | MR imaging compositions and methods |
JPH08502528A (ja) | 1992-10-14 | 1996-03-19 | スターリング ウィンスロップ アイエヌシー. | キレート化ポリマー |
CA2150477A1 (fr) | 1992-11-30 | 1994-06-09 | Robert Allen Snow | Ciblage sequentiel des sites tumoraux a l'aide de conjugues oligonucleotidiques d'anticorps et de conjugues oligonucleotidiques complementaires de radionucleides chelates |
JPH08507750A (ja) | 1992-12-15 | 1996-08-20 | ザ・ウエルカム・ファウンデーション・リミテッド | ジヒドロフォレートレダクターゼを用いる免疫反応試薬 |
US5559214A (en) | 1993-05-28 | 1996-09-24 | Sterling Winthrop Inc. | Unsymmetrical complexing agents and targeting immunoreagents useful in thearpeutic and diagnostic compositions and methods |
AU7244894A (en) | 1993-06-07 | 1995-01-03 | Wellcome Foundation Limited, The | Immunoreactive reagents employing monoamine oxidase |
DE4326466A1 (de) | 1993-08-06 | 1995-02-09 | Boehringer Mannheim Gmbh | Infrarot-Farbstoff-markierte Nucleotide und ihre Verwendung in der Nucleinsäure-Detektion |
US5730968A (en) | 1994-03-31 | 1998-03-24 | Sterling Winthrop Inc. | Segmented chelating polymers as imaging and therapeutic agents |
DE4445065A1 (de) | 1994-12-07 | 1996-06-13 | Diagnostikforschung Inst | Verfahren zur In-vivo-Diagnostik mittels NIR-Strahlung |
US5591217A (en) | 1995-01-04 | 1997-01-07 | Plexus, Inc. | Implantable stimulator with replenishable, high value capacitive power source and method therefor |
AU4497096A (en) | 1995-01-30 | 1996-08-21 | Daiichi Pure Chemicals Co., Ltd. | Diagnostic marker |
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US6628982B1 (en) | 2000-03-30 | 2003-09-30 | The Regents Of The University Of Michigan | Internal marker device for identification of biological substances |
US7286867B2 (en) | 2003-10-16 | 2007-10-23 | Brookhaven Science Associates, Llc | Combined PET/MRI scanner |
WO2007008232A2 (fr) * | 2004-09-03 | 2007-01-18 | Board Of Regents, The University Of Texas System | Ablation locoregionale interne de tissus anormaux par des radionucleides |
GB0422004D0 (en) | 2004-10-05 | 2004-11-03 | Amersham Plc | Method of deprotection |
HUE038724T2 (hu) | 2004-11-24 | 2018-11-28 | Bayer Healthcare Llc | Eszközök és összeállítások fluidumbejuttatáshoz |
EP1853161A4 (fr) | 2004-12-29 | 2011-03-23 | Siemens Medical Solutions | Systeme d'imagerie par tep/rm combine et detecteur tep base sur une photodiode a avalanche utilises en imagerie simultanee tep/rm |
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EP1888145A1 (fr) | 2005-05-16 | 2008-02-20 | Mallinckrodt Inc. | Seringue a cylindres multiples possedant un collecteur integre |
DE102005023906B4 (de) | 2005-05-24 | 2013-01-31 | Siemens Aktiengesellschaft | Verfahren zur Ermittlung von Positronen-Emissions-Messinformationen im Rahmen der Positronen-Emissions-Tomographie |
DE102005040107B3 (de) | 2005-08-24 | 2007-05-31 | Siemens Ag | Kombiniertes PET-MRT-Gerät und Verfahren zur gleichzeitigen Aufnahme von PET-Bildern und MR-Bildern |
DE102005045600B4 (de) | 2005-09-23 | 2008-01-17 | Siemens Ag | Injektor und Verfahren zum Unterstützen der Bildgebung an einem Patienten |
US20080146914A1 (en) * | 2006-12-19 | 2008-06-19 | General Electric Company | System, method and apparatus for cancer imaging |
-
2007
- 2007-06-22 EP EP07110922A patent/EP2005970A1/fr not_active Withdrawn
-
2008
- 2008-06-20 WO PCT/EP2008/057886 patent/WO2009000777A2/fr active Application Filing
- 2008-06-20 US US12/666,205 patent/US20110243847A1/en not_active Abandoned
- 2008-06-20 SI SI200830844T patent/SI2170405T1/sl unknown
- 2008-06-20 PL PL08774183T patent/PL2170405T3/pl unknown
- 2008-06-20 ES ES12199299.4T patent/ES2534970T3/es active Active
- 2008-06-20 EP EP15155866.5A patent/EP2907526A1/fr not_active Withdrawn
- 2008-06-20 DK DK12199299T patent/DK2572735T3/en active
- 2008-06-20 SI SI200831412T patent/SI2572735T1/sl unknown
- 2008-06-20 PT PT121992994T patent/PT2572735E/pt unknown
- 2008-06-20 DK DK08774183.1T patent/DK2170405T3/da active
- 2008-06-20 EP EP12199299.4A patent/EP2572735B1/fr active Active
- 2008-06-20 ES ES08774183T patent/ES2395436T3/es active Active
- 2008-06-20 EP EP13174573.9A patent/EP2647392A3/fr not_active Withdrawn
- 2008-06-20 EP EP08774183A patent/EP2170405B1/fr not_active Revoked
- 2008-06-20 EP EP12168380A patent/EP2514442A3/fr not_active Withdrawn
- 2008-06-20 PL PL12199299T patent/PL2572735T3/pl unknown
-
2013
- 2013-04-11 US US13/860,675 patent/US9179882B2/en active Active
-
2015
- 2015-04-22 CY CY20151100372T patent/CY1116213T1/el unknown
- 2015-05-04 HR HRP20150472TT patent/HRP20150472T1/hr unknown
- 2015-09-21 US US14/859,595 patent/US9682159B2/en active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5059415A (en) * | 1989-02-21 | 1991-10-22 | The State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon Health | Method for diagnostically imaging lesions in the brain inside a blood-brain barrier |
US6490476B1 (en) * | 1999-10-14 | 2002-12-03 | Cti Pet Systems, Inc. | Combined PET and X-ray CT tomograph and method for using same |
US20020061279A1 (en) * | 2000-04-28 | 2002-05-23 | Degrado Timothy R. | 18F-labeled choline analogs |
US6972122B2 (en) * | 2001-01-05 | 2005-12-06 | Duke University | Contrast enhancement agent for magnetic resonance imaging |
US20080008366A1 (en) * | 2006-06-20 | 2008-01-10 | Vladimir Desh | Simultaneous visualization, analysis and navigation of multi-modality medical imaging data |
Non-Patent Citations (3)
Title |
---|
Andrei Iagaru et al., Breast MRI and 18F FDG TET/CT in the management of breast cancer, Annals of Nuclear Medicine Vol 21(1), 33-38, 2007. * |
B.M. Gallagher et al., Radiopharmaceuticals XXVII. 18F-Labeled 2-deoxy-2-fluoro-d-glucose as a radiopharmaceutical for measuring regiional myocardial glucose metabolism in vivo: Tissue distribution and imaging studies in animals, J. Nucl. Med. 18, 990-996, 1977. * |
Yuka Yamamot et al. 3'-Deoxy-3'-[F-18]Fluorothymidine Positron Emission Tomography in Patients with Recurrent Glioblastoma Multiforme:Comparison with Gd-DPTA Enhanced Magnetic Resonance Imaging, Mol. Imaging Biol. 2006, B:340-347. * |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10032268B2 (en) | 2012-08-06 | 2018-07-24 | Koninklijke Philips N.V. | Dynamic contrast-enhanced imaging based permeability metric |
US11730831B2 (en) | 2019-03-26 | 2023-08-22 | Sicreations, Llc | Imaging agents and methods of using the same |
WO2020243585A1 (fr) * | 2019-05-29 | 2020-12-03 | Sicreations, Llc | Procédés de conservation d'un sujet et utilisation d'agents de contraste d'imagerie |
US11833227B2 (en) | 2019-05-29 | 2023-12-05 | Sicreations, Llc | Methods for preserving a subject and using imaging contrast agents |
US11054534B1 (en) | 2020-04-24 | 2021-07-06 | Ronald Nutt | Time-resolved positron emission tomography encoder system for producing real-time, high resolution, three dimensional positron emission tomographic image without the necessity of performing image reconstruction |
US11300695B2 (en) | 2020-04-24 | 2022-04-12 | Ronald Nutt | Time-resolved positron emission tomography encoder system for producing event-by-event, real-time, high resolution, three-dimensional positron emission tomographic image without the necessity of performing image reconstruction |
CN115785468A (zh) * | 2022-11-21 | 2023-03-14 | 苏州大学 | 一种用于富集细胞外囊泡的zif-8-dspe材料及其制备方法和应用 |
Also Published As
Publication number | Publication date |
---|---|
CY1116213T1 (el) | 2017-03-15 |
US9682159B2 (en) | 2017-06-20 |
PL2572735T3 (pl) | 2015-07-31 |
WO2009000777A2 (fr) | 2008-12-31 |
EP2514442A2 (fr) | 2012-10-24 |
EP2572735A1 (fr) | 2013-03-27 |
EP2647392A2 (fr) | 2013-10-09 |
PL2170405T3 (pl) | 2013-06-28 |
SI2170405T1 (sl) | 2013-01-31 |
US9179882B2 (en) | 2015-11-10 |
EP2514442A3 (fr) | 2013-03-20 |
US20130224113A1 (en) | 2013-08-29 |
DK2170405T3 (da) | 2013-01-07 |
DK2572735T3 (en) | 2015-03-30 |
EP2647392A3 (fr) | 2014-01-08 |
EP2572735B1 (fr) | 2015-02-25 |
US20160008496A1 (en) | 2016-01-14 |
ES2534970T3 (es) | 2015-04-30 |
EP2005970A1 (fr) | 2008-12-24 |
ES2395436T3 (es) | 2013-02-12 |
EP2907526A1 (fr) | 2015-08-19 |
HRP20150472T1 (en) | 2015-06-05 |
WO2009000777A3 (fr) | 2009-08-13 |
PT2572735E (pt) | 2015-05-18 |
WO2009000777A4 (fr) | 2009-10-01 |
EP2170405A2 (fr) | 2010-04-07 |
EP2170405B1 (fr) | 2012-09-12 |
SI2572735T1 (sl) | 2015-05-29 |
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