US20040248126A1 - Method of detecting toxic substance - Google Patents
Method of detecting toxic substance Download PDFInfo
- Publication number
- US20040248126A1 US20040248126A1 US10/487,439 US48743904A US2004248126A1 US 20040248126 A1 US20040248126 A1 US 20040248126A1 US 48743904 A US48743904 A US 48743904A US 2004248126 A1 US2004248126 A1 US 2004248126A1
- Authority
- US
- United States
- Prior art keywords
- process according
- mrna
- genes
- gene
- yeast
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Definitions
- This invention relates to biology-based processes for detecting toxic substances, and specifically to processes for detecting toxic substances which comprises detecting mRNA that is transcribed in the presence of test materials by a particular gene from yeast.
- Japan are marketed in Japan.
- the devices for evaluation based on emission intensity of luminous bacteria are commercially available (MICROTOX, azur, Co., USA; LUMIS, drlange, Co. Germany).
- MICROTOX azur, Co., USA
- LUMIS drlange, Co. Germany
- the invention of the present application relates a process for detecting a toxic substance, which comprises detecting mRNA that is expressed in the presence of a test material by a cell comprising a yeast gene that is selected from a group consisting of the following, or a gene that is homologous to the yeast genes and is derived from other species, wherein the mRNA corresponds to said yeast gene or said homologous gene thereof:
- yeast genes and the amino acid sequences of the corresponding protein are disclosed in public databases such as MIPS in Germany: Kunststoff Information Center for Protein Sequence, and SGD in USA: Saccharomyces Genome Database, and are known via the internet.
- a gene(s) that is (are) homologous to the yeast genes means genes that comprise a base sequence having a homology of 50% or more, preferably 80% or more to the base sequences of yeast genes, and that encode a protein having the same functions as the proteins encoded by the yeast genes.
- Cells as used herein may be either eukaryotic or prokaryotic cells as long as they comprise the genes as described above.
- Preferred cells are yeast cells.
- mRNA is detected through reverse transcription-PCR.
- Reverse transcription-PCR is well known in the art. See, for example, NAKABEPPU Yusaku, et al.: Cell Technology, suppl. Tips series, Modified PCR Tips, Shujunsha Co.Ltd., 1999, pp25-43.
- the invention comprises:
- Test materials comprising a chemical substance to be tested are added to the medium, and the cells are incubated further for several hours. Concentrations of the test materials are selected to not lead to cell death. Test materials may comprise one or more chemical substances.
- a polynucleotide having a poly T structure which is immobilized on the surface of magnetic beads or latex beads is used to trap the mRNA, and then the mRNA is washed and eluted with spine column in view of the fact that a poly A chain is attached to the 3′ terminus of mRNA, which is readily conducted using a commercially available kit such as Oligotex-dT30 ⁇ Super>mRNA Purification Kit, Takara.
- the mRNA is reverse-transcribed with a reverse transcriptase (Super Script II Reverse Transcriptase; catalogue No. 18064-014, GibcoBRL) using fluorescence-labeled nucleotides.
- labeled cDNAs that are introduced with fluorescence-labeled nucleotides during the reverse transcription are obtained.
- Reverse transcriptases and nucleotides that are labeled with Cy3-dUTP or Cy5-dUTP are also commercially available (for example, Super Script II Reverse Transcriptase; catalogue No. 18064-014, GibcoBRL). Fluorescence-labeled cDNAs are detected with a fluorophotometer.
- RT-PCR is a procedure for detection and quantitative determination of an intended RNA in a form of the amplified cDNA, which comprises reverse-transcribing mRNA into cDNA with a reverse transcriptase, and conducting PCR using the cDNA as a starting material as well as specific primer sets and a thermostable DNA polymerase.
- a microarray containing the gene as described above may be prepared to hybridize them with the cDNAs, thereby facilitating the efficient detections, which is a preferred embodiment of the present invention.
- the mRNA is detected by northern blotting.
- Northern blotting is well-known in the art (OGATA Nobukuni, NOJIMA Hiroshi: Genetic Engineering Keywords Book, revised 2nd ed., Yodosha, cojp, 2000, pp299-301).
- the process comprises
- Procedures of northern blotting comprises electrophoresing the RNA, transferring the pattern to a filter, and hybridizing it with a specific probe labeled with an isotope, thereby analyzing the presences and the amount of the mRNA in a sample as well as the length of the same.
- a microarray containing the gene as described above may be prepared to hybridize them with the cDNAs, thereby facilitating the efficient detections.
- the detection of mRNA is conducted by detecting the production of a polypeptide encoded by the yeast gene as described above.
- the production of a polypeptide may be detected for example using an antibody directed to the polypeptide.
- Toxic substances to be detected according to the present invention include arsenic, cadmium, mercury, 4-nitroquinolin-N-oxide, 2,4,5-trichlorophenol, y-hexachlorocyclohexane, manganese ethylenebis(dithiocarbamate), 2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile, tetramethylthiuram disulfide, Zinc N,N′-ethylenebis(dithiocarbamate), gingerol, acrolein, and dimethylsulfoxide, all of which are mutagenic.
- Yeast Saccharomyces cereuisiae S288C ( ⁇ SUC2mal mel gap2 CUP1)
- YPD medium yeast extract 1%, polypepton 2%, glucose 2%
- One of toxic chemical substances was added to the cells at logarithmic growth phase, and the cells were further incubated for two hours.
- Cells were cultured without any chemical substance in the same condition, and were used as control. Concentrations of the chemical substances were defined to inhibit the growth of the yeast but not lead to death.
- the culture was centrifuged to collect the cells.
- sodium acetate buffer 50 mM sodium acetate, 10 mM EDTA, 1% SDS
- the mixture was shaken at 65° C. for five minutes, followed by returning to room temperature, and obtaining the supernatant, of which the procedures were repeated two times.
- 1 ⁇ 2 amount of a solution of phenol/chloroform was added, and the mixture was centrifuged to give a supernatant, which was added with an equal amount of chloroform, and the mixture was centrifuged to give a supernatant.
- a polynucleotide having a poly T structure which was immobilized on the surface of latex beads was used to trap the mRNA, and then the mRNA was washed and eluted with spine column (Oligotex-dT30 ⁇ Super>mRNA Purification Kit, Takara).
- Reverse transcription of the mRNA was conducted with a reverse transcriptase (Super Script II Reverse Transcriptase; catalogue No. 18064-014, GibcoBRL) using fluorescence-labeled nucleotides to give cDNAs that were introduced with Cy3-dUTP or Cy5-dUTP during the reverse transcription.
- the labeled cDNAs were dissolved in TE buffer (10 mM Tris-HCl/1 mM EDTA, pH8.0), and the solution was dropped on the DNA chip containing the whole genes of yeast (DNA Chip Research Inc. Japan) so that the cDNAs were hybridized on the DNA chip at 65° C. for over 12 hours.
- the fluoresces intensity of the DNA chip was read with a scanner, and the ratio relative to the fluorescence intensity resulting from the absence of chemical substance was estimated as the following, which is shown in Tables 1 to 9:
- the ⁇ ⁇ level ⁇ ⁇ of ⁇ ⁇ expressed ⁇ ⁇ m ⁇ ⁇ RNA in ⁇ ⁇ the ⁇ ⁇ presence ⁇ ⁇ of ⁇ ⁇ chemical ⁇ ⁇ substance The ⁇ ⁇ level ⁇ ⁇ of ⁇ ⁇ expressed ⁇ ⁇ m ⁇ RNA in ⁇ ⁇ the ⁇ ⁇ absence ⁇ ⁇ of ⁇ ⁇ chemical ⁇ ⁇ substance TABLE 1 Unknown protein yeast genes yeast The level of expressed mRNA in the presence of chemical substance/ genes (1) (2) (3) (4) (5) (7) (8) (9) (10) YCR102C 3.4 3.2 2.4 1.1 0.7 0.4 1.1 4.9 9.8 61.5 YDL218W 3.5 1.2 2.6 1.4 0.7 0.9 1.1 1.5 72.5 12.6 YDR533C
- the tables show that the expressed mRNA of about 700 of 2400 unknown yeast genes was induced by any one of toxic chemical substances such as heavy metals, agricultural chemicals, surfactants (Table 1), as well as the expressed mRNA of 167 mitochondria-located genes (Table 2), 52 DNA repair genes (Table 3), 161 energy genes (Table 4), 142 transport facilitation genes (Table 5), 90 stress protein genes (Table 6), 142 metabolism genes (Table 7), 60 detoxification genes (Table 8), and 507 genes belonging to other category (Table 9).
- toxic chemical substances such as heavy metals, agricultural chemicals, surfactants (Table 1)
- Table 2 the expressed mRNA of 167 mitochondria-located genes
- Table 3 52 DNA repair genes
- 161 energy genes Table 4
- 142 transport facilitation genes Table 5
- 90 stress protein genes Table 6
- 142 metabolism genes Table 7
- 60 detoxification genes Table 8
- 507 genes belonging to other category Table 9
- the ⁇ ⁇ level ⁇ ⁇ of ⁇ ⁇ expressed ⁇ ⁇ m ⁇ ⁇ RNA in ⁇ ⁇ the ⁇ ⁇ presence ⁇ ⁇ of ⁇ ⁇ chemical ⁇ ⁇ substance The ⁇ ⁇ level ⁇ ⁇ of ⁇ ⁇ expressed ⁇ ⁇ m ⁇ ⁇ RNA in ⁇ ⁇ the ⁇ ⁇ absence ⁇ ⁇ of ⁇ ⁇ chemical ⁇ ⁇ substance .
- “Intensity” indicated in the rightmost column of Tables 1 to 9 is a value of the level of expressed mRNA of each gene in control cells as divided by the average level of the expressions of the whole genes. When the intensity is low, the error of measurement may be possibly large. The detection is considered more precise when expression magnification (expressed mRNA in the presence of chemical substance/expressed mRNA in the absence of chemical substance) is larger.
- Yeast gene as used in the processes according to the invention is selected, of which the intensity is preferably 0.3 or more, more preferably 0.5 or more, and of which the expression magnification is preferably 3 or more, more preferably 5 or more.
Abstract
Biology-based processes for detecting toxic substances are provided. The processes comprise detecting mRNA that is expressed in the presence of toxic substances by a cell comprising a yeast gene as followed, or a gene that is homologous to the yeast genes and is derived from other species, wherein the mRNA corresponds to said yeast gene or said homologous gene thereof.
Description
- This invention relates to biology-based processes for detecting toxic substances, and specifically to processes for detecting toxic substances which comprises detecting mRNA that is transcribed in the presence of test materials by a particular gene from yeast.
- Environmental chemical fate search has been conducted every year for 24 years from 1974 through 1998 by Environment Agency, and revealed that about 40% of 775 chemical substances that have been searched so far are emitted into the environment. Chemical substances that are industrially produced at the present in Japan are estimated about 50,000, and the production scale and the kinds of chemical substances are increasing year by year. It is known that chemical substances that are accidentally produced by water treatment with chlorine and incineration pollute the environment. Although such facts allow us to predict that there are a large number of chemical substances that have been accumulated in the environment, it is extremely difficult to search and examine individually the all chemical substances.
- Conventional bioassays (approaches to evaluate the harmful effects on biological materials on the basis of their responses) wherein inhibited growth and particular biological responses in individuals and cells of fishes, daphnia and shellfish are used as indicators make it possible to determine the presence or absence of the toxicity of chemical substances in the environment, but neither possible to evaluate the characters nor origins of the toxicity. The evaluation methods based on the activity of nitrite-forming bacteria or nitrate-forming bacteria (Japanese Patent Publication (kokai) No. 123705/1994, Japanese Patent Publication (kokai) No. 2000-206087) and the activity of iron bacteria have been proposed, and devices such as Acute toxiciants monitor (Fuji Electric Corporate Research and Development, Ltd. Japan) are marketed in Japan. In foreign countries, the devices for evaluation based on emission intensity of luminous bacteria are commercially available (MICROTOX, azur, Co., USA; LUMIS, drlange, Co. Germany). However, those devices still involve conventional bioassays, and never provide any detailed information of toxic chemical substances.
- In Japan, the risk control of chemical substances is reconsidered every time a chemical substance pollution is newly found, and official regulations and self-imposed regulations are combined to organize the system for risk control. However, any system has not been yet organized that could quickly respond to the present complicated and diversified conditions including accidental productions and environmental emission of toxic chemical substance as typified by trihalomethane and dioxin. Animal experiments as used in the method for evaluation of toxic substance of “Law Concerning Examination and Manufacture, etc. of Chemical Substances” are expensive and time-consuming, and are not accepted across the world. Although, as such, the control system has been continuously discussed, it has not been successfully accomplished because there is no way to dissolve the problem. Thus, a method for detect readily chemical substances occurring in the environment is desired.
- The inventors of the present application found that a toxic substance induces the expression of mRNA from particular yeast genes, and accomplished the present invention.
- Specifically, the invention of the present application relates a process for detecting a toxic substance, which comprises detecting mRNA that is expressed in the presence of a test material by a cell comprising a yeast gene that is selected from a group consisting of the following, or a gene that is homologous to the yeast genes and is derived from other species, wherein the mRNA corresponds to said yeast gene or said homologous gene thereof:
- YBR072W, YCR102C, YCR107W, YDL218W, YDL243C, YDR453C, YDR533C, YFL014W, YFL056C, YFL057C, YGR110W, YJR155W, YKL071W, YKR076W, YLL060C, YLR460C, YMR090W, YNL331C, YNL332W, YNL335W, YOL150C, YOL165C, YPL171C, YPR167C, YBL048W, YBL064C, YBL107C, YBR008C, YBR173C, YBR256C, YBR296C, YDL021W, YFL022C, YFL024C, YFL061W, YGL121C, YGL158W, YGR043C, YHR029C, YHR112C, YHR139C, YHR179W, YHR209W, YIR030C, YJR010W, YJR048W, YKL001C, YKL107W, YKR075C, YKR097W, YLL056C, YLR297W, YLR303W, YML087C, YMR096W, YNL274C, YOL151W, YOR226C, YOR338W, YOR391C, YPL280W, YDR406W, YJL153C, YLR346C, YOR049C, YOR153W, YPL088W, YAL034C, YDL124W, YDL174C, YDR476C, YGL156W, YGR035C, YGR157W, YGR213C, YGR281W, YGR284C, YHL047C, YHR043C, YHR044C, YHR054C, YJR073C, YKL165C, YLR008C, YMR315W, YNL211C, YOL031C, YOL101C, YOR303W, YAL005C, YAR031W, YBL005W-A, YBL022C, YBL041W, YBL049W, YBL075C, YBL078C, YBR062C, YBR169C, YBR294W, YCL020W, YCL035C, YCL043C, YCL050C, YCL057W, YCR012W, YCR013C, YCR060W, YDL007W, YDL027C, YDL097C, YDL110C, YDL126C, YDL169C, YDR070C, YDR155C, YDR158W, YDR204W, YDR210W, YDR214W, YDR258C, YDR313C, YDR368W, YDR435C, YER012W, YER037W, YER091C, YER103W, YFL044C, YFR003C, YFR010W, YFR020W, YFR024C, YFR044C, YFR053C, YGL006W, YGL048C, YGL062W, YGL141W, YGL157W, YGL163C, YGL180W, YGL184C, YGR010W, YGR028W, YGR032W, YGR048W, YGR124W, YGR135W, YGR142W, YGR161C, YGR192C, YGR197C, YGR201C, YGR212W, YGR231C, YGR244C, YGR254W, YGR268C, YHL030W, YHR016C, YHR018C, YHR055C, YHR087W, YHR166C, YIL160C, YIR017C, YJL034W, YJL048C, YJL052W, YJL144W, YJL163C, YJR009C, YJR069C, YJR074W, YJR130C, YJR149W, YKL065C, YKL073W, YKL103C, YKL142W, YKL210W, YKL218C, YKR011C, YKR018C, YKR046C, YKR049C, YLL024C, YLL026W, YLR027C, YLR080W, YLR107W, YLR121C, YLR132C, YLR133W, YLR155C, YLR158C, YLR161W, YLR195C, YLR217W, YLR328W, YLR336C, YLR345W, YLR370C, YLR423C, YML004C, YML092C, YML128C, YML130C, YML131W, YMR040W, YMR118C, YMR214W, YMR251W, YMR297W, YMR322C, YNL036W, YNL055C, YNL071W, YNL094W, YNL134C, YNL155W, YNL160W, YNL239W, YNL241C, YOL005C, YOR020C, YOR027W, YOR037W, YOR059C, YOR120W, YOR134W, YOR152C, YOR173W, YOR289W, YOR362C, YPL240C, YPR030W, YAL008W, YAL023C, YAL060W, YAL062W, YAR009C, YBL101C, YBR006W, YBR046C, YBR052C, YBR053C, YBR056W, YBR099C, YBR137W, YBR139W, YBR149W, YBR170C, YBR177C, YBR203W, YBR207W, YBR212W, YBR239C, YBR284W, YBR293W, YCL018W, YCL033C, YCL040W, YCL049C, YCR062W, YCR067C, YCR082W, YDL010W, YDL020C, YDL024C, YDL054C, YDL095W, YDL100C, YDL115C, YDL144C, YDL198C, YDL223C, YDL245C, YDL246C, YDR001C, YDR032C, YDR058C, YDR072C, YDR127W, YDR168W, YDR169C, YDR188W, YDR231C, YDR261C, YDR264C, YDR272W, YDR293C, YDR304C, YDR330W, YDR403W, YDR411C, YDR427W, YDR436W, YDR497C, YDR511W, YDR516C, YDR519W, YDR545W, YEL012W, YEL030W, YER004W, YER009W, YER021W, YER035W, YER053C, YER079W, YER094C, YER096W, YER125W, YER158C, YER163C, YER175C, YER177W, YER178W, YER185W, YFL006W, YFL010C, YFL016C, YFL029C, YFL030W, YFL031W, YFL032W, YFL038C, YFL041W, YFR004W, YFR047C, YFR050C, YFR052W, YGL011C, YGL013C, YGL037C, YGL047W, YGL053W, YGL091C, YGL094C, YGL127C, YGL150C, YGL199C, YGL207W, YGL248W, YGR008C, YGR037C, YGR055W, YGR101W, YGR130C, YGR154C, YGR194C, YGR221C, YGR232W, YGR248W, YGR253C, YGR256W, YHL008C, YHR027C, YHR053C, YHR057C, YHR111W, YHR138C, YHR161C, YHR164C, YHR169W, YHR174W, YHR176W, YHR199C, YIL010W, YIL034C, YIL041W, YIL045W, YIL087C, YIL107C, YIL142W, YIL155C, YIR034C, YIR036C, YIR037W, YIR038C, YIR039C, YJL001W, YJL031C, YJL035C, YJL053W, YJL057C, YJL066C, YJL068C, YJL082W, YJL099W, YJL102W, YJL151C, YJL152W, YJL161W, YJL164C, YJL171C, YJL172W, YJL210W, YJL219W, YJR008W, YJR045C, YJR046W, YJR106W, YJR117W, YJR137C, YKL007W, YKL026C, YKL035W, YKL091C, YKL104C, YKL117W, YKL145W, YKL146W, YKL151C, YKL152C, YKL153W, YKL193C, YKL195W, YKL213C, YKL215C, YLL028W, YLL039C, YLL058W, YLR054C, YLR103C, YLR120C, YLR136C, YLR149C, YLR152C, YLR178C, YLR259C, YLR299W, YLR324W, YLR327C, YLR348C, YLR350W, YLR356W, YLR362W, YLR387C, YLR429W, YML054C, YML070W, YML100W, YML117W, YML125C, YMR004W, YMR008C, YMR009W, YMR020W, YMR067C, YMR089C, YMR097C, YMR102C, YMR105C, YMR107W, YMR152W, YMR180C, YMR184W, YMR191W, YMR219W, YMR271C, YMR275C, YMR295C, YMR314W, YMR316W, YNL006W, YNL007C, YNL012W, YNL044W, YNL045W, YNL074C, YNL092W, YNL093W, YNL104C, YNL115C, YNL156C, YNL231C, YNL234W, YNL237W, YNL281W, YNL305C, YNL333W, YNR010W, YNR019W, YNR033W, YNR059W, YNR068C, YNR069C, YOL032W, YOL036W, YOL047C, YOL071W, YOL082W, YOL083W, YOL117W, YOL119C, YOL126C, YOL131W, YOL153C, YOL162W, YOL163W, YOL164W, YOR019W, YOR035C, YOR036W, YOR099W, YOR117W, YOR124C, YOR130C, YOR132W, YOR157C, YOR185C, YOR197W, YOR259C, YOR261C, YOR273C, YOR288C, YOR332W, YOR336W, YOR347C, YPL017C, YPL087W, YPL106C, YPL109C, YPL149W, YPL154C, YPL196W, YPL206C, YPL222W, YPR023C, YPR024W, YPR026W, YPR067W, YPR103W, YPR108W, YPR151C, YAL012W, YBR029C, YBR222C, YCL009C, YCL027W, YCL064C, YCR098C, YDL222C, YDR055W, YDR077W, YDR502C, YEL001C, YEL042W, YER026C, YER106W, YGR136W, YGR138C, YHR137W, YHR142W, YIL023C, YIL153W, YJL073W, YJR004C, YJR054W, YKL039W, YKL086W, YKL163W, YKR091W, YLR109W, YLR194C, YLR250W, YMR095C, YMR189W, YNL106C, YNL169C, YNL322C, YOR181W, YOR198C, YOR208W, YOR247W, YPL089C, YAL038W, YAL053W, YBR023C, YBR214W, YBR295W, YCR048W, YDL072C, YDL204W, YDR085C, YDR098C, YDR259C, YDR380W, YDR388W, YDR391C, YDR432W, YDR481C, YDR510W, YER069W, YGL022W, YGL126W, YGL209W, YGL255W, YGR189C, YGR282C, YHL035C, YHR030C, YIL022W, YIL024C, YIL117C, YIL123W, YIL140W, YIL154C, YJL088W, YJL108C, YJL149W, YJL159W, YJL186W, YJR148W, YKL096W, YLR180W, YLR273C, YLR300W, YLR307W, YLR378C, YLR391W, YMR094W, YMR104C, YMR276W, YMR296C, YNL190W, YNL208W, YNL300W, YNR064C, YOL013C, YOL058W, YOR248W, YOR355W, YPL052W, YPL163C, YPR079W, YAR028W, YBR146W, YBR183W, YCL038C, YCR071C, YDL008W, YDR019C, YDR031W, YDR115W, YDR486C, YER038C, YER130C, YFL054C, YGL136C, YGR146C, YGR207C, YHL040C, YIL167W, YJL020C, YKR039W, YLR031W, YLR205C, YMR072W, YMR140W, YMR173W, YMR195W, YMR226C, YNL037C, YNR002C, YOL143C, YOR136W, YOR215C, YOR382W, YOR383C, YPL054W, YPL271W, YPR127W, YAL044C, YAL054C, YAR010C, YAR027W, YAR071W, YBL001C, YBL043W, YBL057C, YBR014C, YBR024W, YBR035C, YBR068C, YBR111C, YBR116C, YBR147W, YBR168W, YBR246W, YBR273C, YCR004C, YCR021C, YCR037C, YCR088W, YDL022W, YDL128W, YDL238C, YDR003W, YDR009W, YDR033W, YDR084C, YDR104C, YDR270W, YDR315C, YDR340W, YDR357C, YDR358W, YDR396W, YDR405W, YDR410C, YDR434W, YDR482C, YDR487C, YDR520C, YDR534C, YDR539W, YEL011W, YEL065W, YEL066W, YER039C, YER044C, YER067W, YER080W, YER107C, YFL020C, YFL028C, YFL043C, YFR015C, YGL001C, YGL008C, YGL068W, YGL073W, YGL104C, YGL113W, YGL154C, YGL167C, YGL229C, YGL242C, YGL249W, YGL253W, YGR052W, YGR060W, YGR065C, YGR106C, YGR111W, YGR220C, YGR257C, YHL023C, YHL048W, YHR004C, YHR037W, YHR071W, YHR092C, YHR190W, YIL007C, YIL033C, YIL070C, YIL088C, YIL111W, YIR002C, YIR016W, YIR035C, YIR043C, YJL012C, YJL083W, YJL089W, YJL116C, YJL131C, YJL132W, YJL196C, YJR061W, YJR086W, YJR142W, YJR161C, YKL008C, YKL013C, YKL041W, YKL067W, YKL138C, YKL139W, YKL150W, YKL175W, YKR006C, YKR014C, YKR070W, YLL023C, YLR023C, YLR093C, YLR118C, YLR142W, YLR225C, YLR241W, YLR251W, YLR252W, YLR270W, YML030W, YML110C, YMR021C, YMR027W, YMR148W, YMR181C, YMR262W, YMR272C, YMR298W, YNL011C, YNL130C, YNL214W, YNL259C, YOL129W, YOR042W, YOR052C, YOR137C, YOR149C, YOR165W, YOR270C, YOR285W, YOR367W, YPL018W, YPL156C, YPL186C, YPL203W, YPL216W, YPL255W, YPR006C, YPR073C, YPR098C, YBR050C, YBR145W, YBR299W, YDR518W, YEL020C, YFL062W, YGL039W, YGL134W, YJL217W, YJR159W, YLR126C, YNL249C, YNL284C, YNL336W, YOL157C, YOR344C, YOR381W, YPL265W, YPR124W, YBR074W, YBR109C, YBR126C, YBR201W, YCR005C, YDL248W, YDR041W, YDR105C, YDR268W, YDR452W, YEL075C, YER046W, YER050C, YER136W, YER159C, YGL250W, YGR019W, YGR042W, YGR053C, YGR066C, YGR247W, YGR255C, YGR295C, YHL044W, YHR145C, YIL058W, YIL065C, YIL083C, YIL098C, YIL172C, YJL030W, YJL185C, YJL213W, YJR029W, YJR099W, YJR122W, YJR125C, YKL190W, YKR020W, YLL025W, YLL051C, YLR043C, YLR090W, YLR100W, YLR108C, YLR290C, YML068W, YMR051C, YMR139W, YMR178W, YMR193W, YNL015W, YNL079C, YNL122C, YNL223W, YNL285W, YNL293W, YNR007C, YNR035C, YNR061C, YOL016C, YOL104C, YOR220W, YOR221C, YOR374W, YPL123C, YPR077C, YPR107C, YPR147C, YBR093C, YBR196C, YEL041W, YEL047C, YER023W, YER119C, YFL055W, YGR209C, YIL124W, YKL187C, YLL055W, YMR318C, YOL152W, YAL007C, YBR067C, YBR115C, YBR285W, YBR292C, YDL043C, YDL123W, YDL131W, YDL168W, YDL212W, YDR056C, YDR132C, YDR154C, YDR183W, YDR216W, YDR253C, YDR295C, YDR494W, YDR513W, YEL072W, YER045C, YER061C, YER181C, YFL052W, YFL058W, YFR030W, YGL089C, YGL096W, YGL114W, YGL193C, YGL202W, YGL204C, YGL259W, YGR006W, YGR070W, YGR088W, YHL034C, YHL036W, YHR048W, YHR104W, YHR163W, YIL060W, YIL136W, YIR024C, YJL036W, YJL045W, YJL060W, YJL101C, YJL155C, YJR085C, YJR109C, YJR156C, YKL070W, YKL161C, YKL221W, YKR071C, YLL009C, YLL050C, YLR092W, YLR145W, YLR156W, YLR163C, YLR220W, YLR280C, YLR311C, YLR390W, YML116W, YMR034C, YMR038C, YMR081C, YMR250W, YNL240C, YNL260C, YNL277W, YNR074C, YOL044W, YOL084W, YOL147C, YOL159C, YOR184W, YOR228C, YOR255W, YPL223C, YPR160W, YDL182W, YBR047W, YBR054W, YBR291C, YDR069C, YER124C, YER131W, YGR044C, YIL094C, YKR007W, YMR240C, YNR050C, YOR007C, YAL015C, YBL065W, YBR105C, YBR182C, YBR186W, YBR244W, YBR272C, YCL069W, YDL025C, YDL059C, YDL085W, YDL113C, YDL244W, YDR018C, YDR054C, YDR202C, YDR223W, YDR350C, YDR353W, YDR374C, YDR512C, YEL052W, YEL070W, YER098W, YFR017C, YGL046W, YGL067W, YGL098W, YGL117W, YGL146C, YGL240W, YGR011W, YGR067C, YGR133W, YGR153W, YGR223C, YHR116W, YHR124W, YIL097W, YIL168W, YJL103C, YJL221C, YJR036C, YJR095W, YKL085W, YKL133C, YKL162C, YKL188C, YKL217W, YKR061W, YKR105C, YLL062C, YLR174W, YLR216C, YLR247C, YLR260W, YLR267W, YLR389C, YML007W, YMR041C, YMR177W, YMR253C, YNL009W, YNL117W, YNL128W, YNL183C, YNR073C, YOL133W, YOL158C, YOR133W, YOR225W, YOR227W, YPL161C, YPL166W, YPL202C, YPL224C, YPR015C, YPR086W, YPR201W, YAL061W, YAL067C, YAR007C, YBL033C, YBL056W, YBL086C, YBR026C, YBR073W, YBR101C, YBR117C, YBR123C, YBR213W, YBR269C, YBR280C, YCR036W, YDL132W, YDL149W, YDL200C, YDL234C, YDL242W, YDR099W, YDR177W, YDR256C, YDR392W, YDR394W, YDR531W, YEL071W, YER014W, YER042W, YER090W, YER184C, YFL059W, YFR042W, YFR046C, YFR049W, YGL026C, YGL058W, YGL185C, YGL227W, YGL252C, YGL254W, YGR089W, YGR112W, YGR134W, YGR276C, YHL019C, YHR012W, YHR017W, YHR028C, YHR106W, YHR109W, YHR156C, YIL036W, YIL046W, YIL143C, YIL152W, YIL159W, YIL164C, YJL071W, YJL094C, YJL154C, YJR056C, YJR072C, YJR110W, YJR139C, YKL025C, YKL034W, YKL064W, YKL171W, YKL196C, YKR012C, YKR068C, YKR069W, YLL001W, YLL057C, YLL061W, YLR064W, YLR070C, YLR099C, YLR144C, YLR157C, YLR160C, YLR164W, YLR364W, YLR421C, YML032C, YML042W, YML112W, YML118W, YMR114C, YMR115W, YMR258C, YNL181W, YNL191W, YNL212W, YNL213C, YNL250W, YNL265C, YNL312W, YNR032W, YOL038W, YOL049W, YOL064C, YOR088W, YOR155C, YOR257W, YOR265W, YOR377W, YOR386W, YPL031C, YPL113C, YPL124W, YPL151C, YPL249C, YPL260W, YPL274W, YPR048W, YPR061C, YPR093C, YPR125W, YPR158W, YPR168W, YPR169W, YPR174C, YPR180W, YPR193C, YPR200C, YAL014C, YAL017W, YAL049C, YBL019W, YBL058W, YBR001C, YBR013C, YBR018C, YBR037C, YBR045C, YBR051W, YBR063C, YBR128C, YBR129C, YBR204C, YBR241C, YBR255W, YBR281C, YCL044C, YCL055W, YCR014C, YCR019W, YCR024C, YCR105W, YDL065C, YDL089W, YDL143W, YDL173W, YDL193W, YDL197C, YDL206W, YDL230W, YDL233W, YDR040C, YDR071C, YDR078C, YDR109C, YDR140W, YDR194C, YDR212W, YDR221W, YDR257C, YDR271C, YDR287W, YDR294C, YDR316W, YDR329C, YDR338C, YDR369C, YDR421W, YDR425W, YDR485C, YDR488C, YDR504C, YDR505C, YDR506C, YDR515W, YEL005C, YEL037C, YEL044W, YER017C, YER048C, YER052C, YER078C, YER089C, YER092W, YER100W, YER162C, YER182W, YFL021W, YFL042C, YFR045W, YFR051C, YFR056C, YGL040C, YGL041C, YGL045W, YGL057C, YGL093W, YGL105W, YGL125W, YGL166W, YGL181W, YGL183C, YGL215W, YGL216W, YGL221C, YGL223C, YGR007W, YGR029W, YGR155W, YGR156W, YGR186W, YGR198W, YGR210C, YGR211W, YGR237C, YGR250C, YGR258C, YGR266W, YGR270W, YGR274C, YGR277C, YHL021C, YHL037C, YHL038C, YHR082C, YHR083W, YHR134W, YHR160C, YHR171W, YHR180W, YHR205W, YIL062C, YIL072W, YIL075C, YIL099W, YIL108W, YIL165C, YIL170W, YIR009W, YIR018W, YIR031C, YIR032C, YJL032W, YJL049W, YJL128C, YJL165C, YJR044C, YJR052W, YJR090C, YJR091C, YJR103W, YJR104C, YJR153W, YKL059C, YKL079W, YKL090W, YKL094W, YKL192C, YKL209C, YKR052C, YKR102W, YKR106W, YLL054C, YLR025W, YLR097C, YLR200W, YLR226W, YLR248W, YLR266C, YLR392C, YLR427W, YML013W, YML029W, YML041C, YML051W, YML078W, YML079W, YML088W, YML099C, YMR056C, YMR068W, YMR091C, YMR110C, YMR160W, YMR186W, YMR255W, YNL005C, YNL026W, YNL039W, YNL063W, YNL064C, YNL077W, YNL083W, YNL147W, YNL176C, YNL194C, YNL253W, YNL257C, YNL261W, YNL264C, YNL276C, YNR006W, YNR034W, YNR047W, YNR051C, YNR071C, YOL065C, YOL067C, YOR005C, YOR008C, YOR022C, YOR023C, YOR058C, YOR069W, YOR087W, YOR138C, YOR229W, YOR256C, YOR267C, YPL005W, YPL020C, YPL022W, YPL105C, YPL147W, YPL150W, YPL152W, YPL164C, YPL168W, YPL180W, YPL188W, YPL194W, YPR025C, YPR047W, YPR049C, YPR066W, YPR081C, YPR134W, YPR140W, YPR148C, YPR155C, YPR172W, YPR185W, YAL018C, YAR064W, YBR012C, YBR076W, YBR287W, YDR043C, YDR250C, YDR373W, YFR014C, YGL191W, YGR180C, YHR136C, YJL026W, YJL037W, YLR038C, YNL058C, YOR031W, YGR087C, YIL166C, YHR008C, YIL129C, YGL256W, YJR030C, YMR077C, YBR264C, YPL177C, YKR040C, YGL056C, YDR128W, YGR139W, YBL101W-A, YOR253W, YOL026C, YDR278C, YHR095W, YCL042W, YNL200C, YPL221W, YLR415C, YMR058W, YPR037C, YER072W, YML028W, YOR325W, YAL039C, YMR112C, YJR107W, YGL088W, YJR058C, YNL142W, YDR090C, YMR071C, YBL093C, YGR293C, YML055W, YDL017W, YDL210W, YGL055W, YCL025C, YDR080W, YDL181W, YNR030W, YJL017W, YIL127C, YDR281C, YDR366C, YFR026C, YJL212C, YPL215W, YEL019C, YBR132C, YHL018W, YNL196C, YPL038W, YAR047C, YPL262W, YHL006C, YPL225W, YBR124W, YOR148C, YKR053C, YBL044W, YER029C, YLR360W, YCL056C, YCR007C, YGR239C, YNL256W, YPR146C, YLR377C, YKL097C, YBR066C, YLR338W, YDL229W, YBR253W, YJR027W, YKL198C, YBL030C, YBR031W, YBR118W, YBR162C, YBR221C, YCR024C-A, YCR106W, YDL046W, YDR012W, YDR133C, YDR134C, YDR276C, YDR342C, YDR343C, YEL027W, YEL034W, YGR038W, YGR243W, YGR279C, YHR094C, YHR105W, YHR175W, YHR181W, YIL056W, YIL162W, YJL059W, YJL097W, YJL158C, YJR105W, YKL051W, YKL056C, YKL097W-A, YKL100C, YKL141W, YKR066C, YLR134W, YLR258W, YLR339C, YML058W, YMR083W, YMR203W, YNL209W, YNL307C, YOL030W, YOR178C, YPL028W, YPR028W, YPR113W, YPR149W, YPR150W, YPR183W, YAL016W, YBL099W, YBL100C, YBR011C, YBR096W, YBR100W, YBR127C, YBR283C, YBR286W, YCL008C, YCL058C, YCR030C, YCR034W, YCR069W, YDL015C, YDL023C, YDL061C, YDL086W, YDR038C, YDR039C, YDR050C, YDR151C, YDR178W, YDR233C, YDR284C, YDR298C, YDR345C, YDR359C, YDR382W, YDR385W, YDR400W, YDR407C, YDR538W, YEL024W, YEL033W, YEL063C, YER057C, YER081W, YER120W, YFL011W, YGL012W, YGL206C, YGR022C, YGR026W, YGR082W, YGR107W, YGR172C, YGR191W, YGR204W, YGR260W, YHL005C, YHL046C, YHR025W, YHR026W, YHR123W, YHR126C, YHR143W, YIL011W, YIL015W, YIL018W, YIL157C, YIR041W, YJL016W, YJL121C, YJL133W, YJL138C, YJL191W, YJR018W, YJR047C, YJR077C, YJR119C, YJR121W, YJR123W, YJR143C, YJR145C, YKL060C, YKL147C, YKL148C, YKL157W, YKL164C, YKL169C, YKR033C, YLL041C, YLL064C, YLR041W, YLR044C, YLR056W, YLR058C, YLR081W, YLR089C, YLR110C, YLR177W, YLR264W, YLR284C, YLR304C, YLR340W, YLR354C, YLR372W, YLR388W, YML022W, YMR007W, YMR011W, YMR015C, YMR092C, YMR101C, YMR156C, YMR205C, YMR215W, YMR261C, YMR323W, YNL069C, YNL135C, YNL195C, YNR076W, YOL039W, YOL073C, YOL086C, YOL120C, YOL156W, YOL161C, YOR002W, YOR009W, YOR010C, YOR085W, YOR108W, YOR128C, YOR129C, YOR142W, YOR161C, YOR176W, YOR230W, YOR298W, YPL004C, YPL036W, YPL048W, YPL057C, YPL059W, YPL061W, YPL135W, YPL179W, YPL218W, YPL220W, YPL246C, YPL272C, YPR063C, YPR080W, YPR181C, YBR290W, YCR010C, YCR091W, YDL107W, YDL129W, YDR066C, YDR529C, YFL026W, YGL018C, YGL059W, YNL144C, YOR003W, YAL037W, YAR023C, YBR003W, YBR020W, YBR044C, YBR091C, YBR185C, YBR282W, YCR015C, YCR038C, YCR043C, YDL119C, YDL146W, YDL220C, YDR057W, YDR123C, YDR125C, YDR222W, YDR225W, YDR277C, YDR286C, YDR347W, YDR408C, YDR438W, YDR479C, YDR483W, YEL039C, YEL057C, YEL073C, YER066W, YER076C, YER084W, YER121W, YER189W, YFL017C, YFL046W, YFR006W, YFR008W, YGL115W, YGL208W, YGL214W, YGL218W, YGR021W, YGR023W, YGR024C, YGR064W, YGR076C, YGR096W, YGR108W, YGR174C, YGR182C, YGR236C, YGR288W, YHL042W, YHR195W, YHR210C, YIL006W, YIL012W, YIL028W, YIL050W, YIL057C, YIL089W, YIL102C, YIL113W, YIL122W, YJL100W, YJL169W, YJL199C, YJR039W, YJR050W, YJR101W, YKL003C, YKL016C, YKL061W, YKL093W, YKL121W, YKL160W, YKL170W, YKL194C, YKR034W, YKR067W, YLR006C, YLR016C, YLR030W, YLR036C, YLR112W, YLR125W, YLR128W, YLR204W, YLR211C, YLR233C, YLR257W, YLR288C, YLR326W, YLR334C, YLR395C, YLR408C, YLR414C, YLR444C, YML050W, YML107C, YML120C, YMR031C, YMR053C, YMR073C, YMR162C, YMR204C, YMR206W, YMR284W, YNL010W, YNL025C, YNL127W, YNL139C, YNL217W, YOL116W, YOL118C, YOR053W, YOR100C, YOR103C, YOR122C, YOR150W, YOR187W, YOR251C, YOR312C, YOR327C, YOR348C, YOR352W, YOR388C, YOR394W, YPL001W, YPL033C, YPL066W, YPL148C, YPL230W, YPL275W, YPL276W, YPR005C, YPR014C, YPR192W, YPR194C, YBR005W, YER025W, YFL027C, YGL080W, YGL205W, YHL028W, YHR185C, YIL076W, YJL166W, YLR046C, YMR035W, YMR238W, YMR252C, YNL192W, YNL202W, YOL108C, YOR385W, YPR165W, YAR033W, YBL038W, YBR009C, YBR010W, YBR151W, YCL067C, YCR096C, YDL137W, YDL192W, YDR073W, YDR086C, YDR224C, YDR377W, YDR378C, YER015W, YGL187C, YHR162W, YJL167W, YJL216C, YKR009C, YLR165C, YMR197C, YNL157W, YOL002C, YOL109W, YOR180C, YPL010W, YPL233W, YBR036C, YDR297W, YGR149W, YGR224W, YNL043C, YPL067C, YPL170W, YCR046C, YDR387C, YFL050C, YGL051W, YHR132C, YIL112W, YJL141C, YKR098C, YLR052W, YLR206W, YML129C, YNL203C, YNR014W, YOL043C, YOL096C, YPR184W, YAL028W, YAL055W, YAR062W, YBL095W, YBL102W, YBR122C, YBR157C, YBR161W, YBR251W, YBR298C, YCR039C, YCR083W, YDL018C, YDL067C, YDL078C, YDL091C, YDL215C, YDL216C, YDR022C, YDR067C, YDR079W, YDR181C, YDR186C, YDR196C, YDR262W, YDR306C, YDR319C, YER188W, YGL004C, YGL035C, YGR036C, YGR062C, YGR120C, YGR131W, YGR141W, YGR167W, YGR287C, YHL024W, YHR080C, YHR097C, YIL077C, YJL046W, YJL070C, YJL096W, YJL113W, YJL146W, YJL180C, YJR019C, YJR049C, YKR058W, YLL005C, YLR078C, YLR151C, YLR271W, YLR295C, YLR351C, YLR375W, YMR023C, YMR025W, YMR135C, YMR210W, YMR267W, YMR278W, YMR293C, YNL073W, YNR037C, YNR040W, YNR072W, YOR028C, YOR316C, YOR328W, YOR363C, YPL039W, YPL040C, YPL099C, YPL107W, YPL134C, YPL138C, and YPL140C.
- The base sequences of those yeast genes and the amino acid sequences of the corresponding protein are disclosed in public databases such as MIPS in Germany: Munich Information Center for Protein Sequence, and SGD in USA: Saccharomyces Genome Database, and are known via the internet.
- In addition to the yeast genes as described above, genes that are homologous to the yeast genes and are derived from other species may be used in the invention. In this context, “a gene(s) that is (are) homologous to the yeast genes” means genes that comprise a base sequence having a homology of 50% or more, preferably 80% or more to the base sequences of yeast genes, and that encode a protein having the same functions as the proteins encoded by the yeast genes.
- Cells as used herein may be either eukaryotic or prokaryotic cells as long as they comprise the genes as described above. Preferred cells are yeast cells.
- Methods for detecting mRNA have been previously known, and any one of those methods may be used in the present invention.
- As an embodiment of the invention, mRNA is detected through reverse transcription-PCR. Reverse transcription-PCR is well known in the art. See, for example, NAKABEPPU Yusaku, et al.: Cell Technology, suppl. Tips series, Modified PCR Tips, Shujunsha Co.Ltd., 1999, pp25-43. For example, the invention comprises:
- (1) adding a test material to the cell, and incubating the mixture;
- (2) extracting mRNA from the cell;
- (3) preparing cDNA from the mRNA via reverse transcription using labeled nucleotides; and
- (4) hybridizing the cDNA as used as probe with the gene as described above.
- Incubation of cells may be conducted using usual media and usual temperatures. Test materials comprising a chemical substance to be tested are added to the medium, and the cells are incubated further for several hours. Concentrations of the test materials are selected to not lead to cell death. Test materials may comprise one or more chemical substances.
- For methods of extraction of mRNA, it is well known that a polynucleotide having a poly T structure which is immobilized on the surface of magnetic beads or latex beads is used to trap the mRNA, and then the mRNA is washed and eluted with spine column in view of the fact that a poly A chain is attached to the 3′ terminus of mRNA, which is readily conducted using a commercially available kit such as Oligotex-dT30<Super>mRNA Purification Kit, Takara. The mRNA is reverse-transcribed with a reverse transcriptase (Super Script II Reverse Transcriptase; catalogue No. 18064-014, GibcoBRL) using fluorescence-labeled nucleotides. As such, labeled cDNAs that are introduced with fluorescence-labeled nucleotides during the reverse transcription are obtained. Reverse transcriptases and nucleotides that are labeled with Cy3-dUTP or Cy5-dUTP are also commercially available (for example, Super Script II Reverse Transcriptase; catalogue No. 18064-014, GibcoBRL). Fluorescence-labeled cDNAs are detected with a fluorophotometer.
- RT-PCR is a procedure for detection and quantitative determination of an intended RNA in a form of the amplified cDNA, which comprises reverse-transcribing mRNA into cDNA with a reverse transcriptase, and conducting PCR using the cDNA as a starting material as well as specific primer sets and a thermostable DNA polymerase.
- In the present step, a microarray containing the gene as described above (DNA tip) may be prepared to hybridize them with the cDNAs, thereby facilitating the efficient detections, which is a preferred embodiment of the present invention.
- As another embodiment of the invention, the mRNA is detected by northern blotting. Northern blotting is well-known in the art (OGATA Nobukuni, NOJIMA Hiroshi: Genetic Engineering Keywords Book, revised 2nd ed., Yodosha, cojp, 2000, pp299-301). For example, the process comprises
- (1) adding a test material to the cell, and incubating the mixture;
- (2) extracting mRNA from the cell; and
- (3) hybridizing the mRNA with the gene as described above.
- Procedures of northern blotting comprises electrophoresing the RNA, transferring the pattern to a filter, and hybridizing it with a specific probe labeled with an isotope, thereby analyzing the presences and the amount of the mRNA in a sample as well as the length of the same.
- In the present step, a microarray containing the gene as described above (DNA tip) may be prepared to hybridize them with the cDNAs, thereby facilitating the efficient detections.
- In further another embodiment of the present invention, the detection of mRNA is conducted by detecting the production of a polypeptide encoded by the yeast gene as described above. The production of a polypeptide may be detected for example using an antibody directed to the polypeptide.
- Toxic substances to be detected according to the present invention include arsenic, cadmium, mercury, 4-nitroquinolin-N-oxide, 2,4,5-trichlorophenol, y-hexachlorocyclohexane, manganese ethylenebis(dithiocarbamate), 2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile, tetramethylthiuram disulfide, Zinc N,N′-ethylenebis(dithiocarbamate), gingerol, acrolein, and dimethylsulfoxide, all of which are mutagenic.
- The following examples are presented for purpose of further illustration of the invention, and such examples are not intended to be limiting the invention in any respect.
- Yeast ( Saccharomyces cereuisiae S288C (α SUC2mal mel gap2 CUP1)) were incubated at 25° C. on YPD medium (yeast extract 1%, polypepton 2%, glucose 2%). One of toxic chemical substances was added to the cells at logarithmic growth phase, and the cells were further incubated for two hours. Cells were cultured without any chemical substance in the same condition, and were used as control. Concentrations of the chemical substances were defined to inhibit the growth of the yeast but not lead to death.
Chemical Substances Concentrations (1) Na2As 0.3 mM (2) CdCl2 0.3 mM (3) HgCl2 0.7 mM (4) PbCl2 2 mM (5) 4-nitroquinolin-N-oxide 0.2 μM (6) 2,4,5-trichlorophenol 16 μM (7) γ-hexachlorocyclohexane 1.3 mM (8) manganese ethylenebis(dithiocarbamate) 2 ppm (9) 2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile 10 μM (10) Tetramethylthiuram disulfide 75 μM (11) zinc N,N′-ethylenebis(dithiocarbamate) 2 ppm (12) 8-methyl-N-vanillyl-6-nonenamide 0.82 mM (13) gingerol 1.36 mM (14) acrolein 0.20 mM (15) dimethylsulfoxide 1.41 M (16) Roundup (trademark, herbicide) 1) 1500-fold dilution (17) sodium dodecylbenzosulfonate 0.02% (18) sodium lauryl sulfate 0.01% - After completion of the incubation, the culture was centrifuged to collect the cells. To the cells, sodium acetate buffer (50 mM sodium acetate, 10 mM EDTA, 1% SDS) was added, and the mixture was shaken at 65° C. for five minutes, followed by returning to room temperature, and obtaining the supernatant, of which the procedures were repeated two times. To the supernatant, ½ amount of a solution of phenol/chloroform was added, and the mixture was centrifuged to give a supernatant, which was added with an equal amount of chloroform, and the mixture was centrifuged to give a supernatant. To the supernatant, an equal amount of isopropanol containing 0.3 M sodium acetate was added, and the mixture was allowed to stand at room temperature for 30 minutes, after which the mixture was centrifuged to give a sediment of the whole RNAs. Seventy % ethanol was added to the sediment, and the mixture was again centrifuged to give a sediment, which was then dried and dissolved in water. mRNA was isolated from the whole RNAs as followings. In view of the fact that a poly A chain is attached to the 3′ terminus of mRNA, a polynucleotide having a poly T structure which was immobilized on the surface of latex beads was used to trap the mRNA, and then the mRNA was washed and eluted with spine column (Oligotex-dT30<Super>mRNA Purification Kit, Takara). Reverse transcription of the mRNA was conducted with a reverse transcriptase (Super Script II Reverse Transcriptase; catalogue No. 18064-014, GibcoBRL) using fluorescence-labeled nucleotides to give cDNAs that were introduced with Cy3-dUTP or Cy5-dUTP during the reverse transcription.
- The labeled cDNAs were dissolved in TE buffer (10 mM Tris-HCl/1 mM EDTA, pH8.0), and the solution was dropped on the DNA chip containing the whole genes of yeast (DNA Chip Research Inc. Japan) so that the cDNAs were hybridized on the DNA chip at 65° C. for over 12 hours. The fluoresces intensity of the DNA chip was read with a scanner, and the ratio relative to the fluorescence intensity resulting from the absence of chemical substance was estimated as the following, which is shown in Tables 1 to 9:
TABLE 1 Unknown protein yeast genes yeast The level of expressed mRNA in the presence of chemical substance/ genes (1) (2) (3) (4) (5) (6) (7) (8) (9) (10) YCR102C 3.4 3.2 2.4 1.1 0.7 0.4 1.1 4.9 9.8 61.5 YDL218W 3.5 1.2 2.6 1.4 0.7 0.9 1.1 1.5 72.5 12.6 YDR533C 3.4 4.9 3.5 1.8 1.3 2.2 1.7 5.4 7.3 12.7 YGR110W 1.6 3.1 2.2 5.9 0.9 0.9 1.7 1.5 6.4 4.8 YKL071W 8.3 3.8 5.4 2.8 1.1 18.6 3.7 24.7 162.2 109.2 YLR460C 2.1 2.1 2.0 1.1 1.3 0.6 1.1 8.1 13.9 31.6 YMR090W 6.9 9.5 2.3 3.5 0.7 3.8 2.7 3.9 16.7 6.1 YOL150C 4.1 3.7 9.9 0.9 1.0 5.2 2.4 3.7 10.8 8.3 YBL048W 2.0 7.9 2.3 2.8 1.3 2.0 1.9 1.2 7.2 4.4 YBL107C 1.4 1.1 0.4 1.5 1.2 1.1 2.1 1.9 1.0 3.1 YFL024C 1.0 1.1 1.1 0.7 1.1 2.0 3.3 0.9 0.5 0.5 YGL121C 2.6 5.0 1.4 4.2 0.9 9.8 4.7 3.0 7.0 15.0 YHR029C 2.8 1.8 1.8 1.8 1.0 2.7 2.0 2.7 13.6 8.6 YHR209W 2.8 1.1 0.8 4.5 1.8 3.2 5.0 2.0 2.9 6.4 YKL107W 2.4 2.5 0.5 0.8 1.1 2.0 1.1 0.9 28.2 8.3 YKR075C 1.5 0.7 2.7 4.5 1.2 1.5 1.4 2.0 0.2 0.6 YLL056C 2.1 2.3 3.0 2.0 1.1 0.6 1.0 1.3 58.8 8.8 YLR297W 2.4 2.1 3.5 1.7 1.3 0.8 1.1 1.3 2.1 5.5 YOR338W 1.8 1.8 0.5 1.7 1.6 2.6 1.3 2.2 0.6 3.5 YOR391C 2.1 2.0 0.9 1.2 1.3 1.6 2.0 2.8 18.8 18.1 YPL280W 1.7 1.9 1.9 2.0 1.4 1.9 1.8 2.3 49.8 14.0 YLR346C 4.4 2.0 2.1 4.5 1.4 5.5 5.6 1.3 8.6 6.6 YOR049C 2.5 0.9 12.8 1.4 1.3 8.4 4.2 0.9 1.1 1.9 YAL034C 1.1 1.8 2.8 1.1 1.0 1.5 1.8 1.0 3.0 3.3 YDR476C 0.7 1.8 6.0 1.2 0.5 3.1 1.5 1.3 1.7 3.4 YGR035C 1.6 0.6 1.2 0.6 1.3 3.3 1.1 0.9 1.1 0.5 YGR284C 1.0 2.0 4.0 1.4 1.2 1.4 2.2 1.1 4.3 1.8 YHR054C 1.7 0.9 2.2 1.0 1.0 2.9 1.6 1.8 2.6 7.7 YLR008C 0.9 0.5 0.7 0.9 1.3 2.7 2.0 1.0 0.4 0.7 YMR315W 4.3 1.8 1.7 4.2 2.9 2.0 2.4 2.6 YNL211C 1.2 1.0 0.8 1.0 1.0 7.4 3.1 1.1 0.8 1.1 YOL031C 0.9 1.9 1.0 1.7 1.2 1.0 2.5 2.1 2.3 1.4 YOL101C 0.9 0.8 0.4 1.7 1.6 0.5 0.7 0.9 0.1 0.3 YAR031W 1.5 1.1 1.1 1.7 1.1 2.9 1.6 1.2 2.7 1.6 YBL049W 2.9 11.8 2.1 2.9 1.1 1.7 1.9 5.2 5.2 YBR062C 1.3 1.7 0.4 1.2 1.4 1.9 1.5 1.9 5.4 2.2 YCR013C 1.3 1.4 5.0 1.1 1.1 1.8 1.6 0.7 0.8 1.3 YDL027C 1.2 2.0 1.7 1.7 1.2 2.1 2.9 1.5 2.0 2.3 YDL110C 1.5 1.4 1.1 2.1 0.8 1.7 2.5 1.8 3.0 2.3 YDL169C 1.7 1.7 1.1 1.3 1.1 2.6 2.1 1.3 7.3 4.7 YDR070C 2.2 6.4 3.6 3.5 0.9 6.2 1.4 1.9 13.9 6.0 YDR210W 1.1 1.0 0.9 1.0 2.0 1.2 1.5 1.4 0.5 1.0 YDR214W 1.3 4.0 4.5 1.3 1.1 1.7 1.5 1.5 5.5 2.4 YDR435C 1.2 1.1 1.2 1.4 1.2 2.5 2.1 1.2 0.8 2.1 YER037W 2.0 2.1 0.8 1.1 1.3 3.2 2.6 1.0 1.0 5.5 YFL044C 1.0 1.5 0.8 2.3 1.6 1.3 1.6 1.4 5.2 3.7 YFR003C 1.2 1.5 0.8 1.6 1.0 2.2 1.4 1.4 8.3 3.1 YFR020W 1.0 0.9 1.2 1.0 0.9 1.4 1.1 0.9 3.7 3.5 YFR044C 0.9 1.3 3.8 1.1 0.9 2.1 1.2 0.8 2.1 2.2 YGR010W 1.2 1.6 0.9 1.2 0.8 1.2 1.7 1.6 13.6 8.9 YGR142W 2.7 6.2 15.3 1.3 1.3 0.9 1.4 1.5 36.8 12.2 YGR161C 2.0 2.2 5.4 3.8 1.0 1.4 1.4 1.3 2.0 3.8 YGR212W 1.5 1.7 1.5 1.3 1.2 1.0 1.1 3.8 YGR268C 1.1 2.3 2.0 2.5 1.1 1.1 1.0 1.1 4.1 1.6 YHR016C 0.8 1.5 1.7 1.5 1.8 3.7 0.8 2.8 2.0 YHR087W 1.2 2.7 8.6 2.8 0.7 4.2 3.4 1.2 4.1 3.9 YJL048C 1.7 2.5 2.0 2.9 0.9 1.5 0.7 1.5 1.2 3.8 YJL144W 1.9 1.6 2.2 1.6 1.2 1.7 1.7 1.3 14.6 8.9 YJL163C 1.2 1.9 1.7 1.5 0.9 2.8 2.3 0.7 14.5 2.5 YJR074W 1.0 1.4 2.0 2.0 0.7 1.2 1.8 1.3 3.7 3.1 YKL065C 1.9 2.0 1.3 1.7 1.0 2.3 3.8 1.8 3.1 3.9 YKR011C 1.1 1.6 0.9 1.6 1.2 2.3 2.7 2.0 4.7 4.4 YKR018C 0.7 1.1 1.7 0.7 0.9 1.7 1.0 0.7 3.9 1.7 YKR046C 1.9 7.8 2.8 1.8 0.6 1.9 1.3 0.8 3.9 2.0 YKR049C 1.6 4.2 1.0 3.2 0.9 3.0 2.4 1.3 2.2 3.2 YLR132C 1.0 1.1 0.3 1.1 1.2 1.1 1.1 0.7 4.5 2.5 YLR161W 0.9 0.8 0.8 0.7 0.9 1.2 1.3 0.8 1.0 1.5 YLR217W 0.9 2.0 2.1 0.7 1.4 1.4 1.5 1.0 3.2 8.2 YLR328W 1.3 1.2 1.3 0.9 0.9 4.8 5.4 1.1 0.9 1.2 YML128C 1.5 3.3 4.1 4.1 0.5 5.1 2.8 1.1 5.1 3.1 YMR040W 3.1 2.9 0.9 2.8 1.7 2.8 5.1 1.7 1.4 1.4 YMR251W 1.3 1.3 1.8 0.6 2.2 1.6 3.1 1.7 3.1 11.6 YMR322C 2.0 4.3 1.5 2.9 1.4 1.8 1.7 2.1 21.3 10.3 YNL094W 0.9 1.4 1.1 1.0 1.4 2.9 1.2 2.0 3.5 2.6 YNL134C 2.3 6.0 4.5 0.9 1.7 1.4 1.5 3.2 6.1 5.9 YNL155W 1.1 1.2 1.1 0.9 1.4 3.0 1.3 1.7 5.8 2.7 YOR059C 1.2 1.2 0.4 0.9 1.4 1.1 2.2 1.3 7.6 4.6 YOR152C 4.5 2.5 3.4 2.9 0.8 4.5 3.2 1.2 10.0 5.0 YOR173W 0.7 2.3 6.3 2.0 0.9 3.5 4.9 1.4 5.2 3.7 YOR289W 1.6 1.5 1.0 2.0 1.2 4.2 6.1 2.4 2.4 1.7 YPR030W 1.7 1.4 1.4 1.0 1.2 1.3 1.2 0.9 2.5 2.4 YAL008W 1.4 2.4 2.0 2.4 0.7 1.6 1.9 1.3 1.8 1.5 YBR053C 1.0 1.6 2.4 2.4 1.6 2.7 4.1 1.2 2.9 2.1 YBR099C 1.0 1.4 7.2 1.8 1.0 0.5 0.9 1.5 3.4 12.9 YBR137W 1.1 2.2 1.4 3.5 0.9 2.4 2.7 2.0 2.2 1.8 YBR203W 1.4 1.4 1.6 2.4 0.9 0.6 0.9 1.3 1.1 1.8 YCL049C 1.9 1.3 1.4 1.2 1.6 2.3 2.1 1.0 2.0 1.9 YCR082W 1.4 1.2 0.7 1.2 1.3 1.3 1.5 1.5 4.3 2.3 YDL054C 1.3 2.2 2.7 1.1 1.2 1.2 0.9 0.7 3.5 2.1 YDL115C 1.4 1.0 0.5 1.8 0.8 1.5 1.8 1.6 6.6 3.6 YDL144C 0.8 0.9 1.2 1.5 1.0 1.8 1.0 0.9 3.6 1.2 YDL223C 0.7 1.1 5.0 2.5 0.9 0.8 1.0 0.3 3.8 1.5 YDR032C 1.7 2.2 3.5 2.5 1.4 2.7 2.8 2.4 3.1 2.9 YDR330W 0.8 1.5 1.2 0.8 1.2 2.3 1.3 1.1 3.9 2.6 YDR411C 0.9 2.8 1.8 1.2 1.6 0.8 2.0 0.9 0.7 1.0 YDR511W 1.3 1.7 0.9 2.3 1.0 2.0 1.5 1.7 2.5 2.2 YDR545W 0.6 1.2 0.6 0.7 1.4 1.0 1.2 0.6 1.8 0.7 YER004W 1.0 1.5 1.9 1.4 1.5 1.2 1.4 1.1 4.5 2.9 YER035W 1.4 1.6 1.6 1.9 1.5 0.9 1.9 1.2 1.2 1.4 YER079W 1.1 1.6 1.9 2.0 0.8 1.5 1.9 1.4 5.3 3.4 YER158C 1.2 0.9 0.9 3.1 0.8 0.7 1.2 0.9 2.1 1.6 YER163C 1.1 2.4 1.2 1.6 0.8 2.0 1.5 1.4 5.4 3.4 YER175C 0.9 1.2 1.3 2.2 0.9 0.8 2.3 1.1 1.9 11.5 YFL006W 0.8 2.8 1.6 1.0 1.4 1.2 1.0 1.0 3.2 1.7 YFL010C 1.0 4.8 1.3 1.0 1.3 1.9 1.5 1.0 3.1 1.4 YFL032W 0.4 1.5 1.6 0.8 0.9 0.6 1.1 0.4 0.5 0.6 YGL037C 1.5 2.7 6.5 2.1 0.9 1.3 2.9 1.2 2.1 1.6 YGL047W 1.0 1.9 1.6 2.3 1.3 1.5 1.7 1.1 4.5 5.7 YGL053W 1.5 1.5 1.2 2.5 2.0 2.7 3.7 1.2 3.3 2.4 YGL199C 1.1 1.7 1.7 1.0 0.7 0.7 1.3 0.7 0.1 YGR101W 1.0 1.3 1.2 1.1 1.2 0.9 1.5 0.8 4.0 1.4 YGR130C 0.9 0.7 0.6 1.6 1.4 0.9 1.3 0.9 2.0 1.5 YGR154C 1.8 2.9 2.2 0.5 1.2 1.4 2.0 1.7 25.2 9.1 YGR221C 0.9 2.2 0.9 1.4 0.9 3.0 1.2 1.1 0.7 YHR138C 2.8 1.8 2.2 2.8 1.5 3.8 3.0 1.4 5.3 4.6 YHR199C 1.9 2.0 3.2 2.0 1.2 1.1 1.1 1.0 8.6 6.0 YIL041W 1.0 1.2 2.1 1.3 0.5 1.0 0.8 0.9 1.8 1.4 YIL087C 1.3 1.9 3.4 1.6 1.4 4.1 1.8 1.1 2.4 1.8 YJL057C 1.5 1.2 1.6 1.7 1.5 1.4 2.7 1.5 7.3 6.1 YJL066C 0.9 1.2 1.2 2.5 0.8 1.4 1.6 0.8 2.0 2.1 YJL082W 1.4 0.8 2.4 1.1 1.7 0.2 0.4 0.9 1.4 2.9 YJL151C 1.0 2.4 3.2 1.2 1.3 2.2 1.4 0.8 0.5 1.6 YJL152W 0.9 1.5 1.8 1.3 1.6 1.5 1.2 0.7 0.3 1.0 YJL161W 1.7 2.2 1.5 4.6 1.1 8.0 3.6 1.4 3.1 2.1 YJL171C 2.3 0.7 2.8 1.4 1.0 2.7 1.4 0.9 1.0 1.7 YJR008W 1.6 1.5 1.2 1.7 1.4 2.2 2.9 1.1 1.8 1.9 YKL151C 1.2 3.1 1.7 2.5 1.0 2.0 5.6 1.0 3.3 3.5 YKL153W 1.1 1.4 2.0 0.7 1.0 2.9 1.1 0.7 0.8 1.4 YKL195W 0.8 0.5 0.4 1.1 1.9 2.5 2.1 1.2 3.6 2.1 YLR054C 2.0 1.5 0.4 2.4 1.3 1.2 1.1 1.1 2.7 1.1 YLR149C 1.4 1.9 3.4 2.3 0.8 1.4 1.6 1.1 6.2 5.2 YLR152C 0.7 1.3 1.1 0.9 1.1 2.1 1.4 1.2 0.6 1.1 YLR324W 0.7 1.2 0.9 1.0 1.3 1.2 1.0 1.0 3.1 1.4 YLR350W 1.2 1.9 3.2 2.3 0.8 1.6 1.2 1.0 0.6 1.4 YLR387C 0.9 1.6 0.8 0.6 1.3 1.9 1.1 1.4 7.8 3.0 YML117W 0.9 2.2 0.9 1.6 0.8 1.0 0.7 0.7 1.0 1.4 YMR009W 2.3 1.9 0.5 1.9 1.9 1.2 1.9 1.4 3.4 2.2 YMR067C 0.9 0.9 1.1 0.4 1.1 1.4 1.2 1.1 4.0 3.5 YMR097C 1.5 1.0 0.7 1.6 0.7 1.2 1.5 1.5 2.1 2.1 YMR102C 1.0 2.9 1.1 0.8 1.2 6.3 1.8 1.0 1.7 2.6 YMR107W 5.0 3.9 1.7 18.4 1.1 1.0 1.2 1.3 6.0 17.1 YMR180C 1.2 0.9 1.0 1.3 1.0 2.4 1.7 1.8 1.8 2.2 YMR184W 1.3 5.4 1.0 1.1 0.8 0.9 1.6 1.9 2.1 0.9 YMR191W 1.3 2.4 1.9 1.6 1.5 1.0 2.0 1.1 2.2 3.5 YMR295C 1.7 1.0 1.2 1.6 1.4 1.9 1.3 1.0 1.0 0.8 YMR316W 3.2 2.9 1.1 1.9 1.1 0.7 2.0 1.6 2.1 3.0 YNL044W 1.3 0.9 2.3 1.3 1.2 0.9 0.9 1.8 0.8 0.8 YNL074C 0.9 1.3 1.8 1.2 1.3 1.7 1.1 0.6 1.5 2.0 YNL092W 1.3 1.4 2.4 1.8 0.9 1.2 1.6 0.9 2.3 1.5 YNL115C 0.7 1.8 1.6 1.4 0.8 9.1 2.4 0.8 2.6 1.9 YNL156C 1.1 1.2 0.9 1.3 1.6 1.3 1.9 1.2 2.4 1.9 YNL234W 1.1 1.1 0.6 1.8 1.7 1.3 1.2 1.3 2.6 3.3 YNL281W 1.0 1.3 2.0 1.4 1.7 0.9 1.2 1.2 2.8 1.6 YNL305C 0.9 2.2 2.7 1.4 1.3 1.1 1.7 0.7 2.9 2.1 YNR068C 1.2 1.5 2.3 2.6 1.7 0.4 1.8 1.1 6.7 14.4 YOL032W 1.3 0.8 2.0 1.3 1.4 2.1 1.4 1.5 4.5 3.0 YOL036W 0.8 0.9 1.3 0.8 1.2 1.2 1.0 0.8 3.1 2.8 YOL047C 1.4 1.1 1.1 2.5 1.4 1.5 1.3 1.1 0.6 2.3 YOL071W 1.3 2.0 1.7 2.0 0.9 1.7 2.0 1.6 4.4 2.3 YOL082W 1.0 1.6 1.6 2.1 1.5 1.8 2.5 1.1 3.4 2.0 YOL083W 1.1 2.3 1.2 2.8 1.4 4.5 3.1 1.3 2.7 2.3 YOL117W 1.0 1.1 0.5 1.4 1.7 2.0 1.6 1.1 1.3 4.1 YOL131W 1.0 1.5 0.6 1.0 1.5 1.1 1.3 1.1 8.4 8.1 YOL162W 2.0 6.9 1.7 1.4 0.9 1.2 2.0 1.6 12.0 6.8 YOR019W 2.9 1.2 0.8 4.7 1.4 1.3 2.8 1.1 3.5 7.1 YOR197W 0.8 1.0 1.1 1.4 0.6 1.3 0.9 0.9 0.8 0.7 YPL087W 1.0 5.1 3.0 7.3 0.6 4.3 4.2 1.0 1.0 2.2 YPL196W 1.3 1.6 1.3 1.7 1.5 2.0 2.4 1.2 10.9 2.8 YPL206C 1.0 2.9 1.4 1.9 0.7 1.8 1.2 1.0 1.7 1.1 YPL222W 0.9 3.5 0.8 1.3 1.2 2.2 1.1 0.7 7.4 3.4 YPR023C 1.2 1.4 1.2 0.8 1.1 1.4 1.2 0.9 4.4 2.8 YPR151C 2.3 2.0 1.5 4.1 1.3 1.6 4.4 1.4 3.0 9.5 YDL222C 0.9 1.1 1.5 3.9 1.0 1.4 1.0 0.7 1.9 1.0 YEL001C 1.0 1.0 1.4 0.7 0.9 1.3 1.1 1.2 2.0 1.2 YER106W 1.3 0.7 1.3 1.2 1.6 1.1 1.0 1.2 0.4 1.8 YIL023C 1.1 1.2 2.1 1.8 1.3 0.9 1.2 0.7 3.5 1.6 YJR054W 0.8 0.9 0.3 0.9 1.0 0.7 0.9 1.6 0.6 YKL086W 1.0 1.1 2.4 2.6 0.8 1.0 0.7 1.1 8.2 20.5 YKR091W 1.5 2.3 0.9 3.5 1.6 1.0 1.3 1.3 1.0 1.6 YLR194C 2.1 2.2 1.3 3.6 1.0 0.9 1.0 1.0 0.9 1.1 YMR095C 1.1 2.0 1.6 1.0 0.9 0.7 1.2 1.2 1.4 YAL053W 0.9 0.9 1.3 2.1 0.8 1.1 0.7 0.8 1.4 0.9 YDL072C 1.3 1.1 3.5 2.1 1.4 1.5 1.8 0.8 1.1 1.5 YDL204W 1.4 1.9 4.8 3.4 1.0 5.6 3.2 1.1 2.3 2.0 YDR391C 1.2 2.0 1.3 1.6 1.2 2.8 2.0 1.4 1.5 2.7 YIL024C 1.4 1.3 1.1 2.1 1.3 1.0 1.3 1.1 2.2 1.8 YIL117C 2.5 1.2 1.0 3.3 0.8 1.2 1.5 1.8 2.3 3.5 YJL108C 1.2 1.2 1.0 2.2 1.5 0.6 0.6 1.0 0.3 0.7 YJL149W 1.2 1.8 1.5 6.8 0.8 0.7 1.3 1.0 1.5 3.8 YJL186W 0.6 0.9 1.2 0.8 0.7 0.7 0.6 0.6 0.2 0.5 YNL190W 1.0 1.4 2.6 0.9 1.0 0.5 0.8 0.8 1.1 1.1 YNL208W 1.5 3.2 2.9 2.1 1.2 1.4 0.9 1.5 2.3 3.1 YNL300W 0.7 0.3 2.9 1.5 0.9 0.4 0.4 0.9 0.2 YNR064C 0.9 0.6 0.9 1.8 1.5 2.1 0.8 0.9 2.1 YOR248W 2.4 0.7 2.9 1.3 0.7 0.2 0.3 0.7 0.1 0.4 YPL052W 1.8 1.7 0.4 1.0 1.7 1.9 1.4 1.7 2.0 4.8 YPR079W 1.0 1.8 1.3 1.5 0.9 1.0 2.3 1.1 1.7 2.8 YAR028W 1.2 1.0 0.7 1.2 0.9 3.3 1.8 1.3 1.0 0.9 YDR031W 1.5 1.1 1.7 1.5 1.2 3.6 1.9 1.4 1.1 2.7 YDR486C 1.1 1.5 1.2 0.9 1.2 2.7 1.8 1.8 2.5 5.8 YER038C 1.2 1.4 0.6 1.2 1.4 2.8 1.5 1.1 0.7 2.5 YGL136C 1.1 1.0 1.2 1.1 1.0 3.1 0.7 1.1 1.3 1.0 YGR146C 1.6 2.0 2.0 2.0 0.9 4.1 2.7 1.4 0.8 3.8 YJL020C 0.7 1.2 0.8 0.8 1.0 2.1 1.3 0.6 1.3 1.0 YLR031W 1.3 1.0 0.7 1.3 1.3 3.0 1.5 0.9 0.9 1.4 YLR205C 1.2 5.1 0.7 1.3 1.3 4.4 9.0 1.7 1.5 5.7 YMR140W 1.0 0.9 1.2 0.7 1.1 17.1 4.3 0.8 1.8 2.3 YMR195W 1.7 3.1 1.2 2.2 1.1 2.6 1.1 1.0 0.2 0.7 YOR215C 1.5 1.3 0.7 1.8 1.8 2.6 2.6 1.7 2.1 1.3 YOR382W 0.7 7.6 3.3 0.5 1.2 13.1 28.4 2.0 1.1 12.8 YPL054W 4.2 5.3 4.9 3.1 1.1 2.3 1.8 1.3 2.5 9.2 YPR127W 1.1 1.4 1.0 1.6 1.1 3.2 1.7 1.2 1.9 2.4 YAR027W 1.8 1.0 1.3 1.4 1.2 2.3 2.2 1.3 2.3 1.7 YBL057C 1.1 0.9 0.6 1.0 1.3 2.2 1.1 1.4 1.6 1.2 YBR116C 0.9 4.8 2.4 2.3 1.1 2.8 1.5 1.1 9.0 8.7 YBR147W 2.2 1.1 1.5 3.2 1.2 2.2 1.2 1.9 0.9 3.6 YBR168W 0.9 0.8 1.0 1.3 1.6 3.5 1.6 1.0 1.1 1.7 YBR246W 1.0 0.8 1.7 0.6 1.1 3.1 1.1 0.9 0.5 0.9 YBR273C 0.8 0.6 0.6 1.3 1.9 2.2 1.4 1.4 2.2 2.0 YDR003W 2.0 2.4 1.6 1.5 1.8 1.8 1.8 1.1 6.6 3.6 YDR340W 1.2 1.4 0.7 0.8 1.1 1.9 2.3 1.3 1.4 2.4 YDR357C 1.3 1.5 0.3 1.3 2.0 1.9 2.2 1.7 1.0 0.9 YDR396W 0.7 1.3 0.6 0.7 1.4 2.0 1.5 1.4 0.3 1.2 YDR434W 0.8 0.8 1.5 1.2 1.0 2.2 1.4 0.9 0.8 1.2 YDR482C 1.1 0.9 0.7 1.1 1.5 1.7 1.2 1.0 0.9 0.8 YDR520C 0.9 2.1 0.9 0.6 1.3 2.3 1.2 1.0 0.8 0.7 YDR534C 0.8 4.8 1.8 0.9 1.0 2.1 9.7 1.0 0.6 7.5 YDR539W 0.7 2.0 1.1 1.0 1.8 2.1 2.3 1.3 0.7 1.2 YER044C 1.2 1.0 2.1 1.3 1.8 3.0 1.8 0.9 0.3 0.7 YER067W 4.0 1.9 5.2 6.0 1.1 2.1 4.9 2.1 1.8 3.8 YER080W 0.8 0.8 1.5 0.5 1.1 5.3 3.0 1.4 4.0 2.7 YGL113W 0.7 0.9 0.9 0.4 1.5 2.1 0.9 0.9 0.7 0.8 YGL242C 0.8 0.9 0.6 0.8 1.4 1.9 2.0 1.5 0.9 1.3 YGR052W 1.6 0.8 3.9 4.6 1.4 2.6 0.8 1.1 0.6 1.7 YGR106C 1.2 0.8 1.9 1.3 0.9 2.0 1.1 1.0 0.7 1.0 YGR111W 1.1 2.0 1.0 1.7 1.0 2.4 1.8 1.8 3.3 2.5 YHL023C 0.7 0.6 1.3 0.7 1.1 1.8 1.0 1.0 1.3 1.1 YHL048W 1.3 1.6 2.8 1.3 1.1 3.7 2.3 1.2 0.8 1.2 YIL007C 1.2 1.0 1.1 1.0 1.4 2.0 1.3 1.2 1.1 1.4 YIR016W 1.1 1.1 1.4 1.6 1.2 2.3 1.7 0.8 1.4 1.3 YIR043C 1.2 1.6 2.2 1.8 1.3 2.4 2.2 1.0 0.8 1.3 YJL012C 0.7 0.6 1.6 0.7 1.5 1.9 0.5 1.0 0.6 1.0 YJL083W 0.9 1.3 0.8 0.9 1.1 2.8 0.7 0.7 0.0 0.4 YJL131C 0.9 0.8 0.5 1.1 1.7 2.2 1.9 1.2 0.5 1.0 YJR061W 1.0 2.1 1.0 0.7 1.1 2.0 0.9 1.9 1.6 1.4 YJR161C 1.2 2.0 2.8 1.8 0.8 2.2 2.6 1.0 0.5 1.2 YKL175W 0.7 1.1 2.1 0.9 1.4 2.2 1.3 0.9 1.1 1.9 YKR070W 1.3 0.8 1.4 1.4 1.1 2.2 1.4 1.3 3.4 2.0 YLL023C 0.7 1.3 5.9 0.9 1.0 2.6 1.5 0.5 1.1 1.5 YLR023C 1.3 1.5 0.9 1.2 1.1 2.6 1.2 0.9 0.7 1.7 YLR225C 0.8 0.7 0.4 0.7 1.6 2.4 1.6 1.2 1.0 1.2 YLR241W 0.9 1.7 1.6 2.1 0.8 1.7 0.9 1.0 1.8 1.5 YLR252W 1.3 1.3 4.6 3.0 1.0 2.8 1.6 1.1 3.1 1.4 YLR270W 1.2 1.1 2.3 1.2 1.1 3.5 3.9 1.1 3.3 2.1 YML030W 1.3 0.8 0.8 1.4 1.9 3.0 2.1 1.4 0.8 0.8 YMR148W 1.0 1.0 1.6 0.9 1.2 2.9 0.8 0.6 1.0 0.8 YMR181C 1.3 1.6 1.8 1.1 1.2 2.1 2.0 0.9 1.9 1.4 YMR298W 1.3 1.3 2.9 0.8 1.5 2.3 1.3 1.1 2.4 2.6 YNL011C 1.1 1.5 0.8 0.9 0.9 2.9 2.9 1.5 3.8 1.6 YOL129W 1.0 1.1 2.5 1.2 1.6 2.2 1.6 0.7 1.2 1.2 YOR042W 0.6 1.4 0.7 0.7 1.3 2.1 1.1 0.9 2.1 1.2 YOR052C 1.5 1.3 0.5 2.4 2.3 2.4 1.4 1.4 1.4 1.3 YOR137C 1.1 1.0 0.9 1.2 1.3 2.1 1.6 0.6 0.7 0.7 YPL156C 1.4 1.4 0.9 2.9 1.2 2.4 3.2 1.2 0.5 2.8 YPL186C 1.6 1.7 1.4 4.5 1.3 3.2 3.2 1.9 2.4 1.5 YPL216W 0.7 0.8 1.3 0.9 0.9 1.8 0.8 0.9 1.8 1.9 YPR098C 1.6 2.6 1.7 1.9 2.0 3.0 2.9 1.1 1.4 1.7 YFL062W 1.3 2.7 1.7 2.4 1.6 1.8 3.5 1.1 0.6 1.2 YJL217W 0.6 0.7 3.1 2.5 0.7 1.7 3.2 4.5 0.7 1.7 YLR126C 0.9 1.5 0.4 0.8 1.3 1.7 3.4 1.8 1.3 3.4 YNL249C 1.3 1.7 0.3 1.5 1.2 0.7 2.3 1.7 2.6 1.7 YNL336W 1.2 1.0 3.4 1.3 1.3 1.4 2.5 0.9 0.7 1.9 YBR074W 0.7 1.3 0.9 0.8 1.3 1.5 2.2 0.7 0.4 0.5 YDL248W 1.1 1.7 2.8 1.7 1.5 2.0 2.5 1.1 0.9 1.4 YDR105C 0.7 1.1 2.3 1.0 0.8 1.4 2.1 0.8 2.3 1.7 YEL075C 1.1 1.1 0.7 1.0 1.1 1.4 1.9 0.7 0.6 0.7 YER046W 1.3 1.9 0.5 1.1 1.6 1.8 2.6 1.5 1.5 1.7 YER050C 1.3 0.9 0.5 2.3 2.2 1.0 2.2 1.5 1.4 1.6 YGL250W 1.1 1.4 1.9 1.8 1.6 1.4 2.0 1.1 1.5 1.2 YGR042W 1.5 1.1 1.2 2.0 1.5 2.2 2.2 1.8 1.3 3.2 YGR053C 1.3 0.7 0.6 2.7 2.1 1.9 3.4 1.5 4.5 2.2 YGR066C 1.6 2.5 1.3 2.5 1.2 1.7 2.1 1.3 2.3 5.0 YGR247W 0.8 1.1 0.8 1.0 1.0 0.9 1.8 0.9 1.1 1.1 YGR295C 1.0 1.6 2.8 2.0 0.9 1.9 2.8 1.1 0.5 1.2 YHL044W 0.9 1.3 1.5 1.4 0.7 1.9 2.0 1.4 1.1 1.9 YHR145C 1.5 1.6 0.6 0.9 1.4 1.3 2.1 1.6 0.8 2.4 YIL058W 2.0 0.9 1.4 0.5 1.3 1.4 2.2 0.8 1.1 1.0 YIL065C 1.0 1.3 0.8 1.6 1.9 1.6 2.0 1.4 3.8 2.1 YIL083C 0.8 1.0 0.9 0.8 1.2 1.4 2.2 1.0 1.0 1.1 YJL185C 0.9 1.0 1.9 1.6 1.0 1.4 2.3 1.0 0.9 1.2 YJL213W 0.8 1.1 0.2 1.2 1.5 2.6 2.1 1.2 1.3 1.5 YKR020W 1.1 1.8 0.9 1.6 1.0 4.5 2.2 1.5 1.9 2.8 YLL025W 0.8 1.3 1.8 0.8 1.1 1.5 1.9 1.0 1.5 2.0 YLR108C 3.2 1.8 4.7 1.8 1.9 1.3 2.6 2.0 7.4 10.4 YLR290C 1.3 1.2 0.8 1.9 2.1 1.7 2.3 1.1 1.2 1.1 YML068W 1.0 3.7 1.0 1.2 1.0 0.9 4.1 1.3 1.3 1.4 YMR178W 1.6 1.0 0.8 0.9 1.1 1.6 2.1 1.6 1.6 1.6 YNL122C 1.2 0.9 1.2 1.3 1.6 1.8 2.1 1.4 1.0 1.2 YNL285W 1.1 1.2 0.6 1.1 1.4 0.8 2.3 1.2 1.4 1.7 YNL293W 1.3 0.8 0.8 1.8 1.3 0.9 2.1 1.0 1.6 2.4 YNR061C 0.8 1.1 2.5 0.8 1.0 1.3 2.6 0.8 0.8 0.9 YOR220W 1.5 1.4 1.7 2.4 1.3 1.2 2.1 0.9 1.8 2.5 YPR077C 1.4 1.4 1.2 2.7 1.4 1.2 2.0 1.5 0.6 2.5 YPR147C 0.9 0.8 1.1 1.4 1.6 2.1 1.8 1.1 1.2 2.4 YEL041W 1.4 1.4 0.8 2.5 0.8 1.2 1.9 1.9 2.4 3.6 YKL187C 0.9 1.0 1.4 1.5 0.8 0.8 0.7 1.1 5.2 8.6 YBR285W 1.6 1.6 0.9 6.2 1.3 2.2 1.5 1.0 4.0 3.1 YBR292C 0.8 4.3 1.2 0.6 1.0 0.8 0.7 0.8 2.1 1.3 YDL123W 1.0 1.3 3.7 1.4 0.8 0.7 1.0 0.8 2.0 2.0 YDR056C 1.4 1.3 2.0 2.0 0.9 1.0 1.4 1.4 1.3 2.3 YDR132C 3.7 1.6 1.4 2.1 1.2 1.9 1.7 2.3 5.9 7.3 YDR154C 1.0 2.1 2.5 1.7 0.8 1.5 0.9 1.1 1.5 1.2 YDR295C 0.8 1.0 0.6 1.0 0.9 1.0 0.8 1.3 2.6 1.3 YDR494W 0.9 0.9 0.2 1.3 1.3 1.4 1.7 1.2 1.2 0.9 YEL072W 3.2 3.5 1.6 1.8 1.5 0.6 1.3 1.6 4.7 4.3 YER045C 1.6 2.1 1.2 1.0 0.9 0.8 1.1 1.4 2.0 1.5 YER181C 1.1 0.4 1.7 2.2 1.0 0.7 1.0 0.9 0.8 YGL114W 1.5 0.8 3.6 1.3 1.3 0.7 1.0 1.1 2.7 5.6 YGL193C 1.1 0.9 0.9 1.4 0.7 0.7 1.0 0.7 0.8 1.0 YGL204C 0.9 2.2 1.2 1.2 0.7 0.3 1.3 0.8 1.0 0.9 YGL259W 1.1 1.6 1.4 1.5 1.1 0.8 1.6 1.3 2.6 2.2 YIL060W 1.0 2.3 0.8 1.0 1.2 0.7 0.9 1.8 0.9 3.0 YJL036W 1.3 1.0 0.6 1.6 0.7 1.1 1.5 1.5 6.6 3.5 YJR085C 1.0 1.9 2.8 4.5 0.6 1.5 1.4 0.9 3.7 2.6 YKR071C 3.6 1.6 1.0 1.1 1.9 0.6 0.9 2.1 4.7 4.9 YLR145W 0.9 1.1 0.6 1.5 1.1 0.6 0.9 1.1 1.9 1.2 YLR156W 1.3 1.0 0.7 0.8 0.8 0.6 1.3 1.0 1.1 2.2 YLR280C 0.6 1.4 0.4 0.6 1.3 0.9 1.5 1.0 0.5 1.3 YLR311C 1.5 1.9 2.8 2.9 0.9 0.4 1.1 1.0 0.9 3.0 YMR034C 1.5 1.3 1.0 6.5 1.3 1.1 1.9 1.2 0.7 2.7 YNL240C 0.8 0.8 0.8 0.6 0.8 0.7 0.7 0.9 5.4 3.1 YNL260C 1.7 1.8 0.5 1.0 1.6 0.8 1.1 1.2 3.8 2.0 YNR074C 1.3 1.7 3.1 1.4 1.2 0.7 1.4 1.5 3.9 3.0 YOL084W 1.0 1.4 1.6 3.6 0.6 1.6 0.8 1.0 2.6 3.4 YOL159C 1.9 2.4 1.7 2.0 0.9 1.0 2.1 1.2 1.1 2.4 YOR228C 1.3 1.1 1.8 1.4 1.2 1.0 1.2 0.7 1.4 1.1 YOR255W 2.5 2.7 1.0 1.5 1.0 0.5 0.9 1.2 0.3 0.8 YBR047W 2.7 2.4 1.1 1.5 0.9 1.1 2.2 11.0 10.0 YER124C 0.5 17.3 0.7 1.2 1.4 2.1 1.0 1.8 0.4 1.4 YKR007W 0.8 0.9 0.8 0.9 1.1 1.6 1.5 1.9 1.1 1.8 YOR007C 1.1 3.3 1.4 0.9 1.1 1.2 0.4 2.1 5.6 2.5 YBL065W 1.2 2.9 1.0 3.5 1.1 0.7 1.0 1.9 20.8 4.2 YDL113C 1.0 1.4 1.2 1.2 1.0 1.2 2.2 1.7 3.8 3.0 YDR018C 1.5 1.3 3.3 2.6 1.3 1.5 1.4 1.4 2.3 4.4 YDR202C 1.1 1.2 1.1 1.3 1.3 1.7 1.6 1.4 4.8 2.4 YDR223W 1.3 4.6 2.0 1.9 1.1 1.4 1.0 1.0 2.7 4.6 YDR350C 0.9 1.5 0.4 1.3 1.3 1.3 1.5 0.9 2.8 2.5 YDR374C 1.9 2.9 1.5 0.8 1.3 1.1 0.9 1.8 10.4 3.9 YDR512C 1.8 4.3 2.5 2.3 0.7 2.1 2.0 1.6 3.6 4.0 YFR017C 1.1 1.4 4.4 4.4 1.2 1.2 1.3 0.8 1.0 7.1 YGL046W 1.6 1.2 1.5 1.4 0.9 1.2 1.0 1.2 0.8 4.5 YGL067W 1.6 1.3 1.7 1.1 0.6 1.0 1.1 1.2 1.0 2.3 YGL098W 1.2 0.8 0.5 1.7 0.8 0.7 1.2 1.3 1.2 2.4 YGL117W 2.3 0.6 0.5 2.0 0.9 0.9 1.3 1.9 0.5 5.8 YGL146C 0.9 1.0 1.1 3.3 1.3 1.2 1.3 1.2 0.9 3.2 YGR011W 1.1 1.5 1.0 1.3 0.9 1.1 1.8 1.4 7.4 9.4 YGR153W 1.5 0.9 1.0 1.1 1.6 0.9 1.4 1.8 2.7 2.5 YGR223C 1.8 1.2 1.5 1.3 1.3 1.2 1.2 1.4 6.2 3.8 YHR116W 0.9 1.2 0.9 2.1 1.6 1.5 1.8 1.1 1.5 2.7 YIL097W 1.2 1.0 1.3 1.2 1.2 2.0 1.6 1.7 4.9 3.4 YKL133C 1.3 12.7 2.4 2.0 1.0 1.7 3.2 1.5 4.1 5.9 YKL162C 1.3 1.0 1.9 0.9 1.1 1.7 1.4 1.5 6.7 4.7 YLL062C 6.5 6.7 4.6 1.1 0.8 0.9 0.7 1.8 14.9 5.4 YLR247C 0.8 1.5 1.0 1.0 1.2 1.2 1.2 1.3 2.5 2.9 YLR267W 0.9 1.7 1.3 1.4 1.2 1.3 1.4 1.4 1.1 4.6 YMR041C 1.2 2.8 1.4 1.2 1.1 0.5 0.5 1.4 6.5 6.0 YMR253C 0.9 1.7 2.0 1.3 0.8 1.7 2.3 1.0 1.5 2.8 YOR225W 1.1 2.8 1.4 1.0 1.3 0.7 0.8 0.8 0.8 3.3 YPL166W 1.0 1.4 1.4 1.4 1.2 0.7 1.8 1.2 1.5 3.1 YPL202C 1.1 1.6 1.0 0.7 1.9 1.4 1.6 1.1 1.8 3.5 YBR101C 1.3 2.2 1.7 1.1 1.2 0.8 0.6 1.0 6.9 3.0 YBR269C 1.2 5.7 2.2 1.1 1.3 1.8 1.3 0.8 2.7 2.6 YBR280C 1.2 1.0 2.7 2.0 1.3 1.6 1.7 1.0 5.3 1.9 YDL234C 1.9 0.9 0.5 1.4 1.0 1.1 1.9 1.3 4.6 2.1 YDL242W 1.3 1.3 1.6 1.5 1.3 0.7 1.1 0.5 4.0 4.1 YDR531W 0.8 0.9 0.7 1.0 2.0 1.2 1.6 1.4 2.9 1.5 YFR042W 1.5 1.2 1.9 1.9 1.8 0.8 1.6 1.0 2.8 2.6 YFR046C 1.1 2.3 1.1 1.6 1.2 1.0 1.0 1.5 5.8 1.5 YGL227W 1.0 0.8 0.9 0.7 1.2 1.1 1.2 1.0 2.4 1.9 YGR089W 0.8 0.8 0.9 0.5 1.1 1.2 0.9 0.8 4.0 1.4 YGR134W 1.1 1.5 0.5 1.3 1.3 1.0 1.0 1.5 2.4 1.9 YHR017W 0.8 1.0 1.3 1.3 1.4 1.1 1.5 1.5 2.9 1.7 YIL152W 1.1 1.3 1.0 1.7 1.0 0.8 1.2 1.0 3.1 1.8 YIL164C 1.2 1.2 1.0 1.2 1.0 1.1 2.0 1.2 4.2 3.0 YJR056C 1.0 2.4 0.8 1.2 0.9 0.5 0.9 1.2 3.5 1.4 YJR072C 0.7 2.5 1.0 0.8 1.1 0.7 0.8 1.3 3.1 1.6 YKL034W 0.8 1.4 1.0 0.9 1.1 1.9 1.4 0.7 2.6 3.7 YKR012C 0.7 1.4 1.0 1.0 1.2 1.4 1.0 1.0 3.9 1.2 YLR064W 1.1 1.1 2.9 1.3 0.8 1.2 0.8 1.0 3.3 2.1 YLR364W 3.3 8.0 1.2 1.5 1.3 1.0 1.0 1.1 8.3 1.3 YLR421C 1.1 1.3 0.9 1.2 0.9 2.6 1.5 1.5 4.5 3.3 YML118W 1.5 0.5 0.7 2.7 0.7 0.8 1.5 0.9 6.6 1.6 YMR114C 1.2 1.4 0.5 2.4 1.2 1.2 1.7 1.1 2.5 1.7 YMR115W 1.0 0.6 1.3 1.1 0.9 1.5 1.0 1.2 5.8 2.1 YMR258C 0.9 1.4 1.2 1.1 0.7 1.2 1.5 0.9 2.3 1.8 YNL181W 1.2 1.2 0.6 1.2 1.4 1.6 0.9 1.9 5.3 2.8 YNL191W 1.5 5.1 4.7 0.7 0.9 0.6 3.0 1.2 3.9 3.2 YNL212W 1.1 1.1 1.1 0.5 0.9 0.8 1.3 1.3 4.6 2.3 YNL265C 1.0 1.3 0.5 1.3 0.9 1.9 1.5 1.4 5.0 2.6 YOR088W 0.7 0.9 1.7 0.9 1.2 0.7 0.3 0.7 2.5 1.3 YOR155C 0.8 1.2 1.7 1.0 1.4 0.8 3.6 1.7 YPL151C 1.0 0.8 1.2 1.2 1.0 0.7 0.7 1.0 4.2 2.0 YPL249C 0.8 0.9 1.1 0.6 0.8 2.5 1.0 1.0 3.0 1.2 YPL260W 0.9 3.9 1.4 0.8 0.8 1.4 1.2 1.1 2.6 2.1 YPR061C 1.3 3.2 1.2 4.9 1.4 0.5 1.8 1.2 3.2 1.9 YPR093C 1.1 1.1 0.7 1.3 1.0 0.7 0.8 1.1 6.6 2.3 YPR158W 1.5 1.5 3.7 0.9 1.6 0.7 1.2 1.2 5.0 3.5 YPR169W 0.9 0.9 0.5 0.6 1.0 1.5 0.9 1.0 3.5 1.4 YPR174C 0.8 0.9 0.8 0.6 1.3 1.1 0.8 1.2 3.2 1.0 YAL014C 1.0 1.6 1.4 1.2 0.8 0.6 1.2 1.2 3.1 2.0 YAL017W 0.6 1.4 2.3 1.2 1.0 1.1 1.3 0.6 1.9 1.6 YAL049C 1.0 2.0 1.7 1.0 0.7 1.5 3.4 1.4 3.0 1.4 YBR013C 1.1 2.7 1.8 1.4 0.9 1.8 1.0 1.4 2.2 2.2 YBR051W 1.2 0.8 1.5 0.3 1.1 1.1 1.1 1.5 1.5 YBR063C 0.8 0.8 0.4 0.6 1.2 1.6 1.6 1.3 2.2 1.6 YBR129C 1.1 0.8 0.6 1.0 1.2 1.9 1.0 1.4 2.3 1.4 YBR255W 1.1 1.6 0.4 0.7 1.2 1.0 1.1 1.8 1.8 1.5 YBR281C 0.8 1.1 3.0 0.5 0.8 0.6 1.2 1.8 1.4 YCL044C 0.8 1.4 2.4 0.6 1.1 1.0 1.0 1.0 3.3 4.1 YDL089W 1.1 1.3 1.4 0.9 1.2 2.0 2.0 1.1 2.3 2.5 YDL173W 1.0 1.2 1.0 0.8 1.3 1.1 1.6 1.5 1.8 1.6 YDL193W 0.9 1.5 1.4 0.8 1.1 2.0 1.5 1.6 2.5 1.4 YDL233W 0.8 2.0 1.0 3.8 0.9 1.0 0.8 1.0 2.1 1.1 YDR071C 1.4 1.1 0.7 1.3 1.1 1.5 1.3 1.6 2.6 1.6 YDR078C 1.1 1.6 3.5 0.8 0.9 0.8 2.8 1.4 2.1 1.4 YDR109C 0.8 1.0 1.0 1.3 1.0 0.9 1.2 1.5 1.9 1.3 YDR140W 1.7 1.4 0.9 1.8 0.7 0.9 1.2 1.5 2.2 2.5 YDR221W 0.8 1.3 0.3 0.8 1.1 1.5 0.9 1.0 2.3 1.4 YDR271C 1.0 0.8 0.7 1.7 0.8 1.4 1.3 0.8 5.4 0.9 YDR316W 1.0 0.8 0.6 0.9 1.5 0.7 0.3 1.4 2.5 1.0 YDR338C 1.1 1.3 1.4 1.0 0.7 0.9 1.1 0.9 2.7 1.7 YDR421W 1.1 1.0 1.0 1.1 0.9 0.5 0.2 0.9 3.8 1.2 YDR425W 1.3 1.7 1.0 2.2 1.4 1.7 1.8 1.2 2.6 2.2 YDR485C 0.8 0.9 0.7 0.9 1.6 1.2 1.2 1.1 2.7 2.0 YDR504C 1.0 1.0 0.9 0.8 1.1 1.2 1.1 0.8 2.3 1.1 YEL044W 0.8 1.5 0.7 0.9 1.2 0.8 0.8 0.8 2.1 1.2 YER092W 1.3 1.3 1.2 1.1 1.2 1.5 1.3 1.1 1.9 1.6 YER182W 1.2 0.8 1.1 1.9 1.2 0.6 0.8 1.4 2.2 1.2 YFL042C 0.8 0.9 0.6 1.1 1.4 1.5 1.1 0.8 2.0 2.0 YFR056C 0.9 1.5 0.7 0.5 1.2 0.3 0.9 1.0 2.4 2.7 YGL041C 0.9 0.6 1.3 1.0 0.6 1.4 1.0 0.8 1.3 0.4 YGL045W 1.4 1.1 1.9 3.4 1.0 0.8 1.7 1.2 2.8 4.2 YGL057C 1.3 1.1 1.4 1.4 1.3 1.3 1.1 1.1 2.1 1.1 YGL183C 1.1 1.4 0.8 0.5 1.6 1.2 1.2 0.8 3.4 2.5 YGL223C 1.1 1.7 1.0 0.7 1.4 1.1 1.2 1.0 2.6 2.0 YGR156W 0.9 1.3 1.7 1.2 1.0 1.2 1.3 1.3 4.0 2.4 YGR198W 0.7 0.9 0.7 1.0 0.8 0.8 0.8 1.0 2.9 1.8 YGR210C 0.9 1.4 1.1 0.9 0.8 0.8 0.8 1.0 3.5 1.8 YGR211W 0.7 1.0 2.0 1.0 0.9 0.6 0.5 1.0 2.9 2.5 YGR237C 0.8 1.3 2.5 0.8 1.2 0.7 1.4 1.0 1.8 1.4 YGR250C 1.3 1.4 1.4 1.5 1.4 1.6 1.2 1.1 2.4 2.8 YGR266W 0.7 0.5 1.0 0.9 0.8 1.2 0.9 0.9 2.0 1.1 YGR277C 1.0 1.9 1.1 0.8 0.8 0.8 1.9 1.3 2.8 1.5 YHL021C 1.6 3.9 5.9 3.2 0.9 1.4 2.7 1.0 2.7 1.1 YHL037C 1.2 1.4 0.9 1.0 0.7 1.0 1.1 0.4 1.1 YHR083W 1.0 0.9 1.4 1.3 0.9 0.9 1.0 1.0 2.0 2.1 YHR134W 1.1 0.7 0.4 1.1 1.1 2.0 1.3 1.2 3.5 1.5 YHR180W 1.5 0.7 1.1 1.5 0.9 1.1 1.1 1.2 4.8 3.5 YIL108W 1.0 1.7 2.2 0.7 1.3 0.6 0.9 0.8 2.4 2.0 YIL165C 1.2 2.3 0.9 1.6 1.6 0.8 1.5 1.1 3.2 3.4 YJL032W 1.1 1.0 0.8 0.9 0.9 0.6 0.9 1.3 3.3 2.0 YJL049W 1.3 0.8 0.5 1.8 1.6 1.5 1.2 1.5 2.0 1.9 YJR044C 1.1 1.2 5.1 1.0 1.0 1.5 2.0 1.0 2.2 1.6 YKL059C 0.8 1.0 0.9 0.7 1.3 0.9 1.0 1.0 2.6 1.2 YKL090W 1.0 0.9 1.0 1.2 1.1 1.0 1.1 1.2 3.9 1.6 YKL094W 1.2 1.6 1.2 1.9 0.9 1.0 1.1 1.3 3.1 1.8 YLR097C 1.1 1.5 1.0 1.6 1.6 1.7 1.8 1.4 2.2 1.1 YLR226W 1.0 1.8 0.3 1.0 1.7 1.1 1.9 1.3 2.1 1.4 YLR392C 1.1 0.9 0.8 1.9 1.0 1.2 1.0 1.3 2.4 2.1 YLR427W 0.6 1.0 0.2 0.5 1.6 1.0 1.2 1.1 2.1 1.3 YML013W 0.8 1.0 0.4 0.6 1.3 0.6 1.3 0.6 2.1 1.2 YML029W 0.6 1.5 1.3 1.0 1.2 1.6 1.1 0.9 2.3 1.8 YML041C 1.2 1.0 0.6 1.0 1.3 1.9 1.4 1.8 3.0 1.5 YML079W 1.0 1.7 1.1 1.5 0.8 1.4 1.2 1.2 1.9 1.4 YMR068W 0.9 0.7 0.8 1.5 1.6 1.1 1.5 0.8 2.4 1.4 YMR160W 0.8 1.3 1.2 1.2 1.4 2.2 1.0 0.9 2.2 1.8 YNL026W 0.7 1.0 1.3 0.8 1.4 1.1 1.5 1.0 2.7 1.8 YNL063W 0.9 1.9 0.9 1.4 1.1 1.1 1.4 1.5 3.0 1.8 YNL176C 1.1 1.3 2.9 1.0 0.8 0.7 0.7 0.9 2.4 2.1 YNL194C 1.6 0.7 2.0 15.2 0.7 0.7 1.5 0.9 2.2 6.4 YNL253W 1.3 1.3 0.6 1.0 1.5 1.3 1.3 1.1 2.8 2.6 YNL276C 1.3 13.1 1.9 0.3 1.1 1.3 0.9 0.7 3.1 1.3 YNR051C 0.7 0.5 1.1 0.6 1.3 1.8 1.3 0.7 2.4 1.4 YOR022C 1.3 1.1 1.1 1.2 1.4 1.2 1.6 1.2 2.0 1.4 YOR087W 0.7 1.0 1.8 1.3 0.8 0.3 0.9 0.8 2.8 1.3 YOR138C 0.8 1.5 0.7 0.8 0.8 1.0 1.1 0.8 2.1 3.7 YOR267C 0.8 0.7 1.0 0.9 1.2 1.6 0.9 0.7 2.4 2.2 YPL005W 1.0 1.0 1.0 1.0 1.4 0.8 2.0 1.0 2.6 2.8 YPL150W 0.7 0.9 1.6 0.9 1.0 0.6 1.2 1.1 3.1 2.0 YPL152W 1.4 1.1 1.4 1.8 1.4 1.2 1.3 1.1 3.6 2.7 YPL168W 1.1 1.5 0.5 1.4 1.0 0.8 1.2 1.2 2.1 1.6 YPL180W 0.9 2.0 0.7 0.6 1.2 1.5 1.0 1.0 1.9 1.8 YPL188W 1.3 1.2 2.9 1.0 0.9 0.6 1.3 1.6 2.5 2.6 YPR049C 1.0 2.5 1.5 1.0 0.7 1.2 1.1 1.1 2.4 2.1 YPR148C 1.1 1.2 0.8 1.3 0.9 1.0 1.6 1.5 2.7 1.7 YPR172W 1.1 1.6 2.2 1.2 1.0 1.7 1.2 1.0 2.1 1.3 YAL018C 2.0 1.9 1.1 11.3 0.8 0.7 1.0 1.6 0.4 YAR064W 2.1 0.9 0.9 2.8 0.8 0.5 1.1 1.1 0.0 0.7 YBR012C 2.5 1.7 1.3 0.8 0.9 1.8 1.5 1.1 1.4 2.6 YBR287W 1.7 1.9 3.1 2.4 1.3 1.4 1.1 1.0 1.2 1.6 YDR250C 1.9 1.4 0.9 3.0 1.0 0.4 1.0 1.1 0.5 YJL037W 1.8 1.4 1.4 2.4 1.5 1.8 1.2 1.2 1.8 2.4 YNL058C 2.0 1.0 2.1 1.7 1.0 0.4 0.7 0.3 0.7 YJR030C 0.7 4.4 0.9 1.2 0.7 0.6 0.7 0.9 0.4 0.5 YKR040C 1.2 3.7 2.4 2.9 0.9 0.9 0.9 1.0 1.3 1.2 YDR128W 0.6 3.9 1.4 0.9 0.8 0.9 0.8 1.1 0.9 1.5 YGR139W 1.3 3.7 0.8 0.7 1.3 0.6 0.8 0.6 0.6 YOR253W 0.9 2.8 1.0 1.4 0.8 0.5 1.3 1.2 0.4 1.0 YOL026C 1.2 2.7 0.7 1.4 1.9 1.0 1.8 1.1 1.2 1.1 YDR278C 1.0 3.2 0.9 1.0 1.1 1.0 0.7 0.5 0.6 0.7 YHR095W 1.1 2.6 1.5 2.1 1.1 1.0 0.8 1.0 1.5 1.2 YCL042W 2.5 7.2 1.1 0.6 0.6 0.7 2.2 YNL200C 1.0 3.0 3.6 2.0 1.0 0.4 1.2 0.7 1.9 1.2 YPL221W 0.9 3.0 1.0 1.8 1.4 1.1 1.3 0.9 0.3 1.3 YLR415C 1.1 2.4 6.7 0.9 0.3 1.2 0.9 0.3 YOR325W 1.0 2.6 1.5 0.3 0.9 0.3 1.2 0.9 YGL088W 0.9 2.1 0.9 1.1 0.6 0.8 1.0 0.5 0.5 0.8 YDR090C 0.9 3.0 0.8 1.2 1.8 1.4 1.5 0.8 1.0 1.5 YMR071C 1.0 2.0 1.1 1.9 1.4 1.2 1.8 1.1 1.6 1.8 YGR293C 0.5 1.9 1.6 0.0 1.1 0.7 1.3 1.3 1.1 YJL017W 1.1 1.7 3.5 1.1 1.3 1.2 0.2 1.0 0.8 1.4 YIL127C 1.1 4.8 0.2 1.2 1.0 0.4 0.6 1.2 0.3 0.5 YDR281C 2.1 2.6 0.4 2.1 1.3 1.5 0.6 1.2 0.2 0.5 YDR366C 0.9 2.0 0.8 0.9 1.0 1.5 1.5 1.1 1.0 1.5 YFR026C 0.9 2.0 1.0 0.8 1.0 1.2 1.3 1.3 1.8 0.6 YAR047C 1.1 1.7 1.5 0.7 1.1 1.3 1.2 0.8 0.5 2.3 YHL006C 0.7 1.4 0.9 0.6 1.1 1.1 1.2 1.1 0.9 0.9 YPL225W 1.3 1.7 1.0 1.6 1.1 1.8 1.7 1.7 1.0 1.6 YBR124W 0.9 1.4 1.5 0.4 1.0 0.6 1.1 1.2 1.1 0.7 YBL044W 0.9 2.7 2.1 0.8 1.2 0.7 1.1 0.7 0.2 0.5 YCL056C 1.3 1.4 0.7 1.0 1.5 1.4 1.6 1.0 1.5 1.6 YCR007C 2.2 1.6 0.9 2.9 1.5 1.4 2.0 1.0 1.4 2.6 YPR146C 0.8 1.6 1.3 0.9 1.2 1.1 1.0 0.8 0.9 1.2 YKL097C 0.9 1.6 0.6 1.4 1.8 0.7 0.8 0.4 0.1 YBR066C 1.9 1.3 1.6 1.6 1.3 1.3 1.3 1.2 0.3 0.9 YLR338W 1.1 1.6 1.4 1.1 0.9 1.1 0.9 0.8 7.9 0.5 YBR162C 0.6 0.5 3.1 0.8 1.3 0.6 0.3 0.8 0.1 0.4 YDL046W 1.2 1.4 5.1 1.3 0.9 1.8 1.2 0.7 1.6 2.3 YDR133C 0.9 1.1 2.9 2.0 1.2 0.7 0.2 0.5 0.1 0.4 YGR038W 0.9 1.2 3.5 0.8 1.3 1.3 1.1 0.7 1.4 1.0 YGR243W 1.4 2.2 9.4 5.0 1.0 1.5 1.9 1.3 0.7 3.0 YHR105W 0.9 0.8 2.4 6.3 1.5 0.2 0.9 1.0 1.1 3.4 YHR181W 0.9 0.7 2.4 1.4 1.0 0.9 0.8 0.9 0.5 1.3 YJL097W 1.0 1.1 3.7 1.6 0.9 1.6 1.0 0.8 0.3 0.7 YKL051W 1.0 1.1 4.7 0.8 0.8 1.0 0.6 0.8 1.3 1.1 YKL100C 0.7 1.1 5.0 1.6 0.6 1.8 1.2 0.7 1.3 1.3 YLR339C 0.7 0.8 3.1 0.8 1.3 0.4 0.4 0.5 0.4 YOL030W 1.0 0.8 4.4 1.0 0.9 0.9 1.3 0.6 1.2 0.6 YPR150W 1.3 1.1 4.3 3.0 1.3 0.9 0.9 0.8 1.2 3.3 YBL100C 0.8 1.8 1.6 0.5 0.6 0.4 1.1 0.6 0.2 0.8 YBR096W 1.1 1.5 2.8 1.6 0.9 1.7 1.9 1.0 1.2 1.6 YBR100W 1.0 1.5 4.8 1.1 0.9 0.5 1.0 0.9 8.5 3.0 YCL058C 1.1 1.6 2.2 1.2 1.7 1.1 0.8 0.9 0.6 1.0 YCR030C 1.1 0.9 3.3 1.0 1.0 1.2 1.0 0.7 0.9 2.0 YDL015C 0.9 0.7 3.6 1.1 1.2 2.5 1.1 0.9 0.7 1.1 YDL023C 0.8 1.6 2.4 1.1 0.6 0.3 1.5 0.7 0.7 1.5 YDL086W 0.9 1.2 1.9 0.9 1.3 0.9 0.8 0.8 1.3 1.1 YDR233C 1.1 1.1 3.2 1.9 0.7 0.8 1.2 1.1 0.2 0.7 YDR359C 0.8 0.7 1.7 1.9 1.3 0.8 1.0 0.8 0.7 1.0 YEL033W 0.9 1.2 2.7 1.1 1.0 0.7 0.3 0.7 0.6 0.4 YGR022C 1.3 1.1 1.7 2.2 1.1 1.3 0.9 0.9 0.2 YGR026W 0.8 1.1 2.9 0.9 0.9 1.5 0.9 0.9 0.8 0.7 YGR107W 1.0 0.8 1.7 0.9 1.1 0.8 1.0 0.9 0.1 0.0 YHL005C 0.9 2.7 2.7 0.2 1.2 1.1 0.8 0.9 0.9 YHR126C 1.1 0.9 2.8 0.6 1.0 1.2 1.1 0.6 0.4 0.7 YHR143W 0.5 0.9 4.9 1.0 1.2 2.1 0.5 1.5 0.2 0.7 YIL157C 1.1 1.3 2.1 1.7 0.8 1.3 1.2 1.0 0.9 0.9 YIR041W 1.6 1.0 2.4 1.4 1.3 1.0 1.6 0.9 1.5 2.5 YJL016W 1.3 1.6 2.7 1.3 1.4 1.5 1.4 0.9 0.6 0.9 YJR018W 0.8 1.2 1.8 0.7 1.1 1.0 0.9 0.7 0.4 0.7 YKL147C 1.0 1.3 1.9 0.9 0.8 0.7 0.8 0.7 1.0 0.5 YKL169C 1.0 1.0 1.6 1.8 0.8 1.2 1.5 1.2 0.3 0.5 YKR033C 0.9 1.2 2.1 1.0 1.0 0.6 1.0 1.0 0.1 1.4 YLL064C 0.8 1.7 1.7 1.9 0.9 1.7 1.1 0.9 1.1 2.5 YLR041W 0.8 1.2 2.2 1.5 1.6 0.5 1.2 0.6 0.4 YLR177W 0.8 1.2 1.8 2.2 0.8 1.1 1.3 0.9 1.0 2.3 YMR007W 1.1 0.9 2.0 0.7 1.3 1.7 3.1 0.7 0.1 YMR156C 1.0 0.9 2.7 1.7 1.2 1.4 1.4 0.9 0.6 1.3 YMR215W 0.8 0.5 2.1 1.2 1.1 0.3 0.3 0.5 0.1 0.2 YNL195C 0.9 1.1 3.5 4.7 0.9 0.8 1.1 0.9 2.6 11.7 YOL073C 0.7 0.9 2.5 0.6 1.1 1.2 1.3 0.7 1.9 1.1 YOR129C 0.6 0.8 3.3 0.8 1.3 0.4 0.4 0.6 0.2 0.4 YOR161C 0.6 1.0 6.0 2.2 1.1 0.9 1.2 0.8 1.0 1.7 YPL004C 0.7 1.2 3.7 1.9 1.4 1.3 2.3 0.9 1.1 1.6 YPL246C 0.7 0.8 2.6 0.9 1.4 1.3 0.8 0.6 0.4 0.5 YPL272C 1.1 0.9 2.2 0.6 1.3 1.1 0.7 0.8 1.2 2.5 YPR063C 1.0 0.8 2.6 0.8 1.2 1.0 0.6 0.7 0.5 0.6 YDL129W 1.0 0.7 1.0 2.3 1.3 0.9 0.9 1.0 0.5 0.9 YDR066C 1.3 1.5 0.9 2.2 1.0 1.4 1.1 1.3 1.5 1.1 YGL059W 1.3 1.5 0.9 3.1 0.7 0.7 1.0 1.4 1.6 1.7 YNL144C 1.8 0.8 1.2 4.5 0.9 1.1 1.1 1.1 0.7 1.9 YAL037W 1.6 0.9 1.1 3.5 1.2 1.1 1.0 1.3 0.6 1.9 YAR023C 1.1 1.0 1.7 2.1 1.3 1.0 1.1 0.8 0.9 1.4 YCR015C 1.1 0.9 0.5 2.1 1.7 1.0 1.5 1.2 0.5 1.0 YCR043C 1.4 0.5 0.8 2.3 0.9 0.8 0.7 1.2 0.3 0.7 YDL146W 1.0 1.2 1.2 2.0 0.7 0.7 1.4 0.9 0.8 2.3 YDR057W 0.9 1.4 1.6 2.6 0.8 0.7 1.4 1.2 1.5 1.1 YDR222W 1.0 1.1 1.7 1.7 1.4 1.3 0.5 1.0 0.6 1.0 YDR286C 1.6 0.9 1.1 2.1 1.0 1.7 1.3 1.9 0.8 1.2 YDR438W 1.2 1.8 0.8 2.1 1.6 1.3 1.4 1.0 1.1 0.8 YDR479C 1.1 1.8 1.0 2.3 0.9 1.6 1.2 0.9 1.2 1.6 YEL057C 1.1 0.6 1.3 2.4 1.0 0.9 1.1 1.2 1.2 1.9 YEL073C 1.6 0.8 1.0 2.8 1.2 1.5 0.8 0.9 0.7 1.2 YER084W 0.8 1.1 1.0 3.9 0.9 0.6 0.8 0.9 0.8 YER121W 1.1 1.2 0.7 7.7 1.3 2.5 1.3 1.3 0.6 0.5 YER189W 0.9 0.8 0.9 1.9 1.3 0.5 0.9 0.7 0.4 0.5 YFL017C 1.3 1.2 0.9 2.3 1.5 1.3 1.5 1.4 0.8 0.6 YFL046W 1.3 0.9 0.7 2.1 1.7 0.7 1.3 1.3 0.7 0.7 YFR008W 1.1 1.0 0.8 2.2 1.1 1.0 1.1 0.9 1.5 1.4 YGL214W 0.9 1.0 1.2 2.6 1.2 0.9 0.8 0.9 0.4 0.7 YGL218W 1.4 0.9 1.4 3.4 1.2 1.1 0.8 1.1 1.3 0.4 YGR021W 0.9 1.5 1.0 8.6 1.0 0.9 1.3 1.4 0.7 0.6 YGR024C 1.2 0.9 0.7 2.6 1.0 0.7 1.3 1.4 0.4 1.2 YGR064W 1.1 1.2 1.6 2.3 0.7 0.6 1.1 1.0 0.1 0.8 YGR182C 1.6 1.2 1.2 2.3 1.1 0.9 0.7 1.1 0.5 0.7 YGR236C 1.6 1.6 0.4 4.1 1.2 1.2 1.0 1.2 1.5 0.7 YHL042W 1.2 0.8 1.3 51.1 1.0 0.7 1.2 1.0 0.8 1.8 YIL012W 1.2 5.8 1.5 2.8 1.5 1.5 0.9 0.9 1.7 2.8 YIL028W 1.0 1.1 0.8 5.4 1.4 0.7 1.1 0.8 0.8 1.7 YIL057C 1.3 1.8 1.1 4.6 1.3 1.2 1.2 1.4 0.1 5.0 YIL089W 1.3 1.3 0.7 3.9 1.6 1.6 1.6 1.1 0.6 YIL102C 1.4 1.6 1.0 6.1 1.5 0.8 1.1 0.7 0.3 YIL113W 0.9 1.0 0.9 2.6 0.6 1.0 1.9 0.7 1.9 2.2 YIL122W 1.2 1.1 1.1 2.1 0.9 0.2 0.8 0.7 0.4 0.8 YJL100W 1.4 2.0 0.9 2.3 1.3 1.1 1.2 1.2 1.8 2.7 YJL169W 0.8 1.1 1.5 2.8 1.4 0.8 0.9 0.7 0.3 0.5 YJL199C 1.1 0.7 0.9 4.5 1.0 1.7 1.0 1.0 1.0 1.6 YJR039W 0.9 0.6 0.8 3.0 1.8 1.0 1.6 1.2 1.8 1.6 YJR101W 0.8 0.6 0.7 2.9 1.8 0.9 1.5 1.1 0.4 0.8 YKL061W 1.3 0.7 0.7 1.8 0.8 1.0 0.9 1.2 0.8 1.0 YKL121W 0.9 7.8 0.8 11.8 1.6 1.2 1.7 1.0 0.8 0.9 YKL160W 1.5 1.0 0.4 1.8 1.1 1.5 1.5 2.1 1.3 1.9 YLR016C 0.7 1.3 0.5 2.0 1.5 0.8 1.1 1.2 0.8 1.1 YLR030W 1.4 1.5 0.8 2.5 1.2 1.5 1.5 0.9 0.3 2.7 YLR036C 1.3 0.8 0.7 2.0 1.5 1.3 1.7 1.2 0.4 1.6 YLR112W 1.1 0.9 1.1 1.7 1.3 1.3 1.0 0.7 0.7 YLR125W 1.4 2.0 0.5 3.1 1.8 0.7 1.3 1.2 0.5 1.7 YLR128W 1.3 1.4 0.8 1.8 1.3 1.3 1.1 0.8 1.7 YLR204W 1.1 0.9 0.5 2.1 2.0 1.5 2.0 1.3 1.4 1.6 YLR211C 1.3 1.0 0.8 7.7 1.7 1.2 1.8 1.1 0.9 1.2 YLR257W 1.5 1.0 0.7 2.4 1.4 1.2 0.8 1.3 1.0 1.1 YLR326W 1.2 1.0 1.5 2.2 1.3 0.4 1.2 0.9 0.7 1.5 YLR334C 1.2 1.1 1.1 2.3 1.8 1.0 1.4 0.9 1.0 0.8 YLR408C 1.3 2.3 0.6 2.3 1.4 1.0 1.0 1.4 0.9 1.1 YLR414C 1.5 1.6 1.4 4.8 1.3 0.6 0.7 0.9 0.2 1.2 YLR444C 0.9 0.8 1.7 5.9 0.7 0.7 0.9 0.9 0.2 0.2 YML050W 1.5 1.2 1.3 2.1 0.8 0.5 0.9 1.1 1.3 1.6 YML107C 1.1 0.7 0.4 1.8 2.2 1.1 1.5 1.3 0.6 0.9 YMR031C 0.7 0.8 1.2 2.1 0.6 0.7 0.8 0.9 1.5 1.1 YMR204C 1.1 1.9 1.3 2.3 1.0 0.6 0.7 1.0 1.0 2.2 YMR206W 1.4 1.4 2.3 3.9 1.1 1.0 1.3 0.9 1.0 9.0 YNL010W 1.5 1.0 0.7 1.9 1.0 1.2 1.1 1.8 0.5 0.6 YNL127W 1.1 1.2 0.7 3.6 0.7 1.2 0.8 1.0 2.7 2.2 YNL217W 1.1 1.2 0.5 1.7 2.1 1.5 1.3 1.4 0.3 0.9 YOL118C 2.6 2.2 1.3 2.2 1.5 3.2 1.1 3.2 YOR053W 1.0 1.1 0.5 1.7 1.7 0.9 1.6 0.9 1.3 0.8 YOR352W 1.3 0.9 1.0 2.2 1.6 0.9 1.8 1.1 1.7 2.0 YOR394W 1.2 0.8 2.2 1.6 1.6 1.7 1.8 1.0 1.1 2.3 YPL033C 0.8 1.0 0.9 5.1 1.3 0.7 1.0 0.7 0.4 1.6 YPL066W 0.9 1.0 1.1 2.0 1.3 1.3 1.3 0.9 0.5 0.8 YPR014C 1.0 0.7 1.1 7.9 0.8 0.9 0.8 0.9 0.9 YBR005W 1.9 2.6 1.1 2.9 0.8 0.7 1.2 0.9 0.4 1.3 YFL027C 0.8 0.8 1.1 1.3 1.1 0.3 0.4 1.1 1.8 1.3 YGL080W 1.3 1.5 1.1 1.3 1.5 1.4 1.5 1.2 1.1 1.2 YMR252C 1.1 1.0 1.5 1.3 1.3 1.0 1.3 1.1 0.9 1.0 YOR385W 2.8 1.2 0.2 2.5 1.5 1.0 1.2 1.0 1.5 2.2 YAR033W 1.0 0.8 1.5 1.1 1.1 1.4 2.1 1.2 1.3 1.6 YBR151W 0.8 0.8 1.3 1.2 1.2 1.7 1.3 0.8 0.8 0.9 YHR162W 1.2 1.2 0.9 1.8 1.2 1.3 1.7 1.4 1.0 1.7 YLR165C 1.4 0.8 1.3 1.1 1.1 1.5 1.4 1.1 1.7 1.0 YNL157W 1.4 1.1 0.7 1.5 1.9 0.9 1.3 1.1 1.7 1.4 YOL002C 0.9 0.7 0.5 1.0 2.0 0.9 0.4 0.8 0.1 0.3 YPL233W 1.2 0.9 0.5 1.1 1.4 0.6 1.0 1.0 0.3 0.6 YGR149W 1.4 1.3 1.8 1.9 1.0 1.7 1.8 0.8 0.6 0.6 YNL043C 1.0 4.4 1.6 1.3 0.8 0.6 0.9 0.9 0.4 0.4 YPL067C 1.2 1.6 2.8 1.4 1.0 0.8 1.2 1.2 0.8 YPL170W 1.2 1.3 0.9 1.1 1.9 1.1 0.6 1.1 1.4 1.0 YGL051W 1.1 1.0 1.6 1.7 1.3 1.0 1.3 0.8 1.1 1.8 YIL112W 1.1 1.4 2.8 1.9 0.6 1.3 1.1 0.9 1.3 2.0 YLR052W 1.0 1.5 0.8 1.3 1.0 0.8 1.0 1.2 0.4 1.1 YNL203C 0.9 1.3 0.3 3.2 1.0 1.7 1.6 0.8 0.3 YNR014W 1.0 0.8 1.7 1.2 1.2 0.7 1.7 0.9 0.3 2.3 YAL028W 0.9 0.7 1.1 2.0 1.0 0.6 1.2 0.8 1.6 1.3 YBL095W 0.8 1.4 1.2 1.4 1.1 0.9 1.1 0.9 1.0 0.6 YBR157C 0.7 1.0 0.4 1.4 1.3 1.2 1.6 0.7 0.6 0.3 YDL091C 1.1 1.3 1.8 1.4 0.7 0.8 1.3 1.3 1.6 1.5 YDL216C 1.1 1.1 0.7 2.0 1.6 1.6 1.2 1.6 1.3 1.3 YDR067C 1.3 1.2 0.7 2.7 0.9 1.1 1.3 1.8 1.0 1.3 YDR186C 0.7 0.9 0.7 0.7 1.3 0.7 1.4 1.2 1.2 1.6 YDR196C 0.9 0.9 0.7 1.1 1.0 1.7 1.7 1.5 1.6 1.1 YDR262W 1.3 1.8 0.8 1.2 1.7 1.3 1.7 1.2 0.9 1.7 YDR306C 0.9 1.2 0.7 1.8 1.7 1.2 1.6 1.3 2.0 1.4 YDR319C 1.3 0.9 0.8 1.1 1.2 1.2 1.7 1.3 1.1 1.1 YER188W 1.3 0.9 1.2 1.9 0.9 1.5 1.2 0.7 0.4 0.9 YGL004C 0.8 1.4 1.3 1.0 1.0 1.4 2.9 1.4 1.8 2.2 YGR141W 0.8 1.6 1.6 1.7 1.1 1.5 1.5 0.9 0.3 1.0 YHR080C 0.6 1.8 1.9 0.7 0.8 1.8 1.1 1.1 1.9 1.2 YHR097C 1.6 0.7 0.7 0.9 0.8 0.8 0.7 0.4 0.6 YIL077C 0.9 0.8 1.2 1.2 1.3 1.8 1.2 0.9 1.5 1.4 YJL046W 0.9 0.9 0.6 1.8 1.0 0.7 1.5 1.1 1.8 2.7 YLL005C 1.0 1.1 1.1 1.2 1.6 1.9 1.3 1.0 0.4 1.0 YLR151C 1.4 2.0 1.4 1.0 1.0 1.4 1.4 1.5 0.9 YLR271W 1.6 1.2 0.8 1.8 1.4 1.4 1.7 1.5 1.0 1.0 YMR025W 1.2 1.2 0.7 1.5 1.3 1.3 1.4 1.2 1.0 1.6 YMR135C 1.0 1.0 1.1 1.9 1.8 1.0 1.0 1.0 1.1 1.4 YMR210W 1.0 1.1 1.8 1.9 0.6 0.8 1.1 1.1 1.5 2.2 YNR040W 0.8 4.9 0.5 0.9 0.9 1.6 2.1 1.3 1.1 0.8 YPL039W 1.2 0.9 0.6 1.3 1.4 1.5 1.5 1.4 1.1 1.0 YPL099C 1.1 1.9 0.7 2.0 0.9 1.2 1.4 1.4 2.4 1.7 YPL107W 1.2 0.8 1.1 1.3 1.0 1.1 1.2 1.5 1.4 1.3 YPL138C 1.1 1.7 1.1 1.8 0.7 0.5 1.1 1.3 1.1 1.5 yeast The level of expressed mRNA in the absence of chemical substance genes (11) (12) (13) (14) (15) (16) (17) (18) Intensity YCR102C 13.5 0.5 1.1 4.1 0.9 1.2 1.1 1.2 0.53 YDL218W 5.7 0.9 1.1 4.8 1.1 3.5 1.1 0.9 0.42 YDR533C 7.7 1.4 3.0 2.9 2.5 6.7 2.3 2.7 1.82 YGR110W 0.5 1.4 3.6 2.8 1.2 17.1 0.9 2.1 0.19 YKL071W 40.3 1.0 8.4 21.9 1.7 2.2 1.0 0.9 0.31 YLR460C 14.3 0.4 0.7 3.5 0.7 1.8 1.0 1.1 0.48 YMR090W 8.8 2.2 6.9 6.5 1.9 5.1 1.8 2.8 1.30 YOL150C 9.4 2.9 8.9 5.7 1.8 3.1 2.7 2.2 0.47 YBL048W 2.0 1.2 2.7 2.0 4.1 5.7 1.3 1.0 0.29 YBL107C 2.9 1.4 2.6 2.5 1.4 1.5 0.9 1.4 1.03 YFL024C 0.6 0.8 0.9 3.3 0.9 1.1 0.9 0.8 0.37 YGL121C 6.1 1.6 7.8 5.8 1.6 8.5 2.7 3.5 0.60 YHR029C 3.8 1.5 4.7 3.5 1.0 1.0 2.1 2.1 0.87 YHR209W 3.3 1.0 2.0 2.2 5.0 3.5 2.6 2.6 0.56 YKL107W 2.0 1.0 1.9 3.4 1.7 3.5 1.6 0.9 0.17 YKR075C 1.3 2.3 3.8 2.7 0.4 4.3 2.4 1.9 1.15 YLL056C 1.7 1.3 6.8 11.0 1.5 4.8 5.3 2.5 0.32 YLR297W 3.5 0.8 0.8 2.3 0.7 1.8 0.7 1.0 0.81 YOR338W 0.8 1.2 1.4 2.5 1.8 1.0 1.1 0.5 0.52 YOR391C 3.2 1.1 2.3 2.4 5.8 2.2 1.0 0.9 0.22 YPL280W 1.9 0.9 2.4 2.4 4.3 1.5 1.2 0.9 0.22 YLR346C 0.5 4.2 6.2 2.2 1.0 2.4 10.6 7.8 0.53 YOR049C 1.1 6.7 7.1 1.5 1.3 4.3 2.6 2.9 0.22 YAL034C 1.5 2.8 4.9 1.2 1.4 1.0 1.2 1.3 0.52 YDR476C 1.6 2.1 2.8 1.1 2.2 2.0 2.4 1.5 0.58 YGR035C 0.4 3.3 2.1 0.8 0.3 1.9 2.5 4.3 1.04 YGR284C 1.7 2.1 3.6 1.2 3.9 1.9 1.3 2.1 2.57 YHR054C 0.9 3.6 5.8 1.0 0.8 2.2 5.1 3.4 0.80 YLR008C 0.8 3.5 6.2 1.6 0.7 1.7 5.4 4.9 2.00 YMR315W 3.2 2.0 2.5 1.3 2.5 1.6 2.1 2.8 1.76 YNL211C 1.1 3.2 9.9 1.1 0.8 9.3 4.2 6.8 0.52 YOL031C 1.3 2.1 2.4 1.1 4.4 1.5 1.2 1.9 1.20 YOL101C 0.9 2.4 0.2 0.8 0.6 3.5 0.6 0.6 1.37 YAR031W 1.4 1.2 3.3 1.4 0.9 3.5 1.6 2.5 1.00 YBL049W 2.2 0.7 3.9 1.5 7.2 6.4 1.1 1.1 0.47 YBR062C 2.3 1.2 2.8 2.6 0.7 2.2 1.4 1.6 0.93 YCR013C 2.4 1.4 3.9 1.5 1.6 1.6 1.1 1.3 2.80 YDL027C 1.7 1.7 3.2 1.1 1.4 1.8 1.4 2.0 0.69 YDL110C 1.9 1.5 2.7 2.7 1.3 3.6 2.0 4.4 1.27 YDL169C 1.2 1.2 3.7 2.7 2.2 3.8 1.5 1.6 0.42 YDR070C 4.1 4.3 6.6 2.0 2.1 15.1 1.2 3.1 0.44 YDR210W 1.0 1.0 2.3 1.1 1.0 1.5 1.9 1.9 1.82 YDR214W 1.9 1.1 5.3 1.2 1.1 0.7 1.2 1.0 1.07 YDR435C 1.3 1.1 2.5 1.3 0.6 2.0 1.3 2.0 1.30 YER037W 1.5 1.2 3.0 1.7 0.8 1.8 1.7 2.6 1.17 YFL044C 2.2 1.2 4.7 1.2 1.0 1.8 1.3 1.4 0.50 YFR003C 1.4 0.9 2.5 2.1 1.0 1.4 1.3 1.8 1.01 YFR020W 1.4 0.9 2.3 1.8 2.6 1.0 1.2 0.9 0.61 YFR044C 1.9 1.2 3.1 0.8 1.5 1.2 1.0 1.0 1.99 YGR010W 1.5 0.9 5.2 1.9 1.3 1.4 0.8 1.3 0.55 YGR142W 2.3 2.0 8.9 0.9 1.3 0.3 1.9 1.5 1.28 YGR161C 0.8 1.7 2.8 0.9 1.7 1.1 1.5 1.8 0.65 YGR212W 0.9 1.5 10.0 1.1 1.1 2.1 3.9 2.2 0.28 YGR268C 0.8 1.0 2.8 1.0 1.5 1.2 1.5 1.4 0.48 YHR016C 2.2 1.3 3.3 0.9 0.6 2.1 1.2 1.4 0.51 YHR087W 3.7 1.4 4.0 1.5 1.9 3.8 1.2 2.9 1.34 YJL048C 3.2 1.1 2.4 1.7 0.6 2.3 1.6 2.5 0.82 YJL144W 3.0 0.8 3.9 1.6 1.0 2.5 2.2 2.4 0.60 YJL163C 3.1 2.0 4.5 1.0 2.0 2.8 1.5 1.7 0.28 YJR074W 1.2 2.0 2.8 1.7 3.4 1.5 1.8 1.9 0.68 YKL065C 1.3 1.3 3.0 2.1 1.7 2.8 2.8 4.6 2.29 YKR011C 1.5 1.1 3.5 1.4 1.8 1.3 1.3 1.9 0.66 YKR018C 1.4 1.0 3.0 1.1 1.0 1.8 1.0 1.2 0.98 YKR046C 2.6 1.3 2.8 1.9 2.9 3.5 1.2 1.9 0.73 YKR049C 2.2 1.2 4.1 2.1 0.9 4.2 1.6 3.3 1.17 YLR132C 0.5 1.0 2.7 1.3 2.3 1.6 1.2 1.6 0.36 YLR161W 1.5 0.8 2.1 1.0 0.6 1.1 1.1 0.9 0.33 YLR217W 0.9 3.8 0.9 0.9 0.8 1.0 1.2 0.35 YLR328W 1.4 1.2 4.3 0.5 0.8 1.4 1.1 0.8 1.04 YML128C 2.9 1.4 4.9 1.4 2.6 5.6 2.0 5.5 1.66 YMR040W 1.5 2.1 5.2 1.8 2.0 2.7 3.1 3.7 0.62 YMR251W 2.8 1.2 2.5 1.5 0.4 1.3 1.5 0.9 0.20 YMR322C 3.2 1.1 2.1 2.7 3.6 1.8 1.4 0.8 0.18 YNL094W 1.7 1.2 3.4 1.0 1.5 1.5 1.1 1.3 0.66 YNL134C 5.0 1.1 3.1 1.4 0.8 2.1 1.3 2.0 2.51 YNL155W 2.2 1.1 4.4 2.1 2.0 2.0 1.1 1.6 1.89 YOR059C 1.0 1.0 3.3 2.2 3.5 1.8 1.3 1.7 0.71 YOR152C 2.7 2.9 7.4 1.7 3.6 2.1 4.0 2.2 0.42 YOR173W 2.3 1.9 3.8 2.8 0.7 5.7 1.7 3.8 0.54 YOR289W 2.6 1.5 4.3 2.0 1.6 3.0 2.3 3.9 0.74 YPR030W 1.2 1.4 3.2 1.5 1.5 3.1 1.4 2.1 0.30 YAL008W 2.2 1.3 2.2 2.6 0.9 4.2 1.4 1.9 1.04 YBR053C 2.3 1.1 2.4 1.0 0.7 2.8 1.9 2.4 1.25 YBR099C 0.4 1.0 2.1 1.6 0.8 0.5 0.8 0.9 0.47 YBR137W 2.4 1.4 2.1 1.8 0.6 2.8 1.4 2.6 1.40 YBR203W 1.3 1.6 2.4 1.3 1.0 18.0 1.4 2.2 0.38 YCL049C 1.6 1.4 2.4 1.8 1.4 2.1 1.4 1.4 0.86 YCR082W 2.0 1.0 2.0 2.4 1.6 2.2 1.2 1.7 1.62 YDL054C 2.1 1.1 2.7 1.2 1.0 1.0 1.0 1.0 0.92 YDL115C 1.8 1.1 1.9 2.3 1.2 1.6 1.3 1.8 0.83 YDL144C 1.9 1.0 2.1 1.2 1.0 1.1 0.9 0.9 0.52 YDL223C 5.2 1.0 3.1 1.3 3.1 7.2 0.9 1.0 0.32 YDR032C 3.3 1.8 2.9 2.8 1.3 3.8 1.9 3.5 3.50 YDR330W 0.9 1.0 2.2 1.1 1.6 1.4 1.5 1.3 0.53 YDR411C 1.3 1.5 1.9 0.8 4.1 1.5 1.5 1.3 0.56 YDR511W 1.2 0.8 3.1 2.2 0.8 2.2 1.3 1.5 0.66 YDR545W 0.7 0.9 2.0 0.7 0.9 0.9 0.9 0.9 1.06 YER004W 2.2 1.7 4.6 1.8 1.4 2.3 1.4 1.2 1.48 YER035W 1.4 1.1 1.9 1.0 0.9 2.1 2.2 2.1 0.85 YER079W 2.1 0.9 2.1 1.6 0.5 1.4 1.0 1.6 0.69 YER158C 2.3 1.0 3.1 0.9 0.6 1.6 1.6 1.2 0.61 YER163C 1.6 1.0 2.9 1.9 1.6 2.4 1.2 1.2 0.62 YER175C 1.1 0.9 4.3 1.1 1.3 2.8 0.9 1.2 0.53 YFL006W 1.2 1.2 3.1 1.7 2.4 1.1 1.0 0.8 0.82 YFL010C 1.4 1.5 3.3 1.4 1.7 1.4 1.9 1.6 0.77 YFL032W 1.1 0.7 2.4 0.6 2.0 0.7 1.7 0.8 1.62 YGL037C 3.9 0.8 2.3 1.0 0.8 1.5 1.3 2.6 4.58 YGL047W 1.9 1.1 2.6 2.3 1.7 2.9 1.1 1.2 0.97 YGL053W 1.3 1.3 3.3 1.1 1.1 3.9 2.2 3.7 1.26 YGL199C 0.9 2.0 0.8 1.6 1.6 1.2 1.0 0.36 YGR101W 2.0 1.0 2.4 0.9 1.1 2.0 1.0 1.1 1.04 YGR130C 0.8 0.7 1.9 0.9 1.2 2.2 1.3 1.6 0.78 YGR154C 1.5 0.9 2.5 2.2 0.7 2.0 1.0 1.2 0.36 YGR221C 0.5 1.6 2.3 1.4 1.5 2.7 1.3 1.3 0.29 YHR138C 1.6 1.8 4.0 3.4 2.2 3.3 5.0 7.1 1.89 YHR199C 1.9 1.1 2.1 2.0 2.8 3.3 1.1 0.9 0.63 YIL041W 1.4 1.0 2.3 1.3 1.3 0.7 0.8 1.1 1.33 YIL087C 2.8 1.1 2.4 1.3 0.4 5.6 1.7 1.6 0.68 YJL057C 2.0 1.0 2.5 1.6 1.4 1.9 1.4 1.5 0.51 YJL066C 0.8 1.0 2.2 1.0 1.3 2.8 1.4 1.5 0.43 YJL082W 1.0 1.3 2.1 0.5 3.2 0.2 0.6 0.3 2.07 YJL151C 1.0 1.3 2.4 1.3 1.0 2.5 3.5 2.4 1.69 YJL152W 1.0 1.0 1.8 1.4 0.8 1.6 2.5 1.7 0.80 YJL161W 3.7 1.0 2.5 2.2 0.6 4.4 1.9 2.1 0.44 YJL171C 2.2 1.0 2.9 1.0 1.8 1.0 3.6 2.9 1.94 YJR008W 1.4 1.3 2.0 1.2 0.9 3.3 1.5 2.7 0.87 YKL151C 2.3 1.0 2.0 1.3 1.4 3.7 1.4 1.8 1.02 YKL153W 2.1 1.1 2.4 1.1 1.5 1.1 0.9 1.3 1.60 YKL195W 1.0 1.1 2.4 1.6 0.9 1.7 1.4 1.6 1.58 YLR054C 0.7 1.1 3.2 1.1 0.7 0.9 1.6 1.1 0.14 YLR149C 2.8 2.0 3.0 1.2 1.3 2.8 1.3 3.0 0.33 YLR152C 3.6 1.0 2.8 1.2 0.8 2.8 1.5 1.8 0.46 YLR324W 0.9 0.8 2.3 1.4 1.6 1.7 1.2 1.2 0.49 YLR350W 0.9 1.8 4.5 2.8 1.6 2.9 1.6 1.1 1.52 YLR387C 0.9 1.1 3.6 1.7 1.9 1.0 1.0 1.4 1.20 YML117W 0.8 0.8 2.0 0.8 2.8 0.7 1.1 1.3 0.70 YMR009W 2.1 0.6 2.3 1.9 0.6 2.3 2.7 2.5 0.75 YMR067C 1.1 1.1 2.2 1.5 1.4 1.0 1.0 1.0 0.49 YMR097C 1.5 1.2 2.1 2.1 1.7 1.7 1.4 1.8 0.59 YMR102C 1.5 2.4 4.4 0.7 0.7 1.1 2.4 2.8 0.94 YMR107W 3.0 0.8 1.8 8.1 1.9 12.0 1.3 8.1 0.49 YMR180C 0.7 1.2 3.1 1.7 1.0 1.8 1.4 1.7 0.57 YMR184W 1.5 1.7 2.3 1.5 1.1 1.2 1.4 2.0 0.68 YMR191W 2.3 1.8 3.4 1.5 2.7 1.7 1.2 2.1 0.99 YMR295C 1.2 1.1 2.3 1.3 0.9 1.9 2.1 3.4 3.43 YMR316W 1.5 1.9 2.9 1.3 0.5 1.3 6.9 6.4 1.25 YNL044W 1.1 1.0 3.1 1.2 2.4 1.0 3.1 3.4 2.56 YNL074C 1.3 0.9 2.3 0.6 1.0 0.7 1.1 1.3 0.68 YNL092W 0.7 1.1 2.3 1.2 2.7 1.3 1.7 1.6 0.16 YNL115C 1.1 0.8 2.5 1.0 1.6 3.1 1.6 2.6 0.80 YNL156C 1.4 0.9 2.0 1.4 1.8 2.1 1.8 1.9 1.85 YNL234W 1.3 1.1 2.5 1.5 1.4 2.6 1.0 1.0 0.49 YNL281W 1.6 0.7 2.0 1.2 1.2 0.5 0.9 0.9 1.79 YNL305C 1.8 1.1 2.6 1.3 1.6 2.5 1.7 1.6 1.35 YNR068C 1.1 1.3 3.7 1.8 1.0 1.4 1.0 1.0 0.24 YOL032W 1.4 1.0 2.3 1.3 0.9 2.4 1.7 1.8 0.77 YOL036W 2.2 1.0 2.5 1.0 2.0 1.0 1.1 0.9 0.48 YOL047C 0.9 0.8 2.0 1.2 12.3 1.3 1.5 1.0 0.19 YOL071W 4.3 1.0 2.5 2.5 0.7 4.6 1.3 2.0 1.08 YOL082W 1.6 1.0 2.4 1.4 1.0 2.4 1.6 2.5 0.60 YOL083W 1.3 1.2 2.3 1.4 1.0 3.8 1.4 3.2 0.41 YOL117W 1.0 0.9 2.2 1.7 1.1 2.2 1.3 1.4 0.21 YOL131W 1.4 0.9 3.1 2.3 1.4 0.7 1.1 0.9 0.15 YOL162W 4.3 1.4 3.8 1.4 0.6 0.9 1.2 0.9 0.26 YOR019W 1.7 1.0 2.2 1.4 0.7 2.6 1.7 2.8 0.40 YOR197W 1.0 1.0 2.1 0.7 1.7 1.0 1.5 1.5 1.30 YPL087W 2.5 1.8 4.4 1.2 1.3 1.8 2.1 2.7 1.49 YPL196W 1.7 0.9 2.1 1.6 0.7 4.3 1.4 2.3 0.92 YPL206C 1.5 0.8 2.5 1.1 0.8 1.2 1.4 1.9 1.22 YPL222W 1.2 1.3 3.0 1.1 0.9 2.2 1.1 0.9 0.26 YPR023C 1.7 0.9 2.0 0.9 0.8 1.4 1.0 1.1 0.81 YPR151C 1.4 0.9 2.0 1.4 0.7 2.8 1.3 1.4 0.16 YDL222C 2.6 1.0 2.2 1.3 7.1 6.5 0.9 1.3 0.50 YEL001C 1.2 1.1 0.9 1.3 3.0 1.2 0.7 1.3 2.81 YER106W 1.0 0.9 1.0 1.5 6.8 0.9 0.8 0.8 0.25 YIL023C 1.1 0.9 1.1 0.7 5.6 1.1 1.2 1.0 0.93 YJR054W 0.7 0.9 0.4 1.2 3.1 0.6 0.9 0.9 0.52 YKL086W 0.7 0.6 1.3 2.9 5.0 0.6 0.9 1.0 0.28 YKR091W 1.1 0.9 1.0 1.9 6.3 1.6 1.6 1.3 0.45 YLR194C 1.4 1.6 4.0 1.2 3.6 0.9 1.0 0.9 0.60 YMR095C 2.1 0.8 3.4 2.2 41.7 1.0 1.0 1.0 0.23 YAL053W 2.3 0.6 1.1 0.7 2.9 1.1 1.2 1.6 1.60 YDL072C 1.4 1.2 1.6 1.8 2.6 2.6 1.6 2.8 3.25 YDL204W 3.2 0.9 3.2 2.4 3.6 8.6 1.8 2.7 0.73 YDR391C 1.9 1.4 1.8 2.3 3.5 3.0 1.8 2.4 1.05 YIL024C 0.6 0.7 1.0 1.5 3.1 1.0 1.1 1.0 0.35 YIL117C 1.8 1.4 1.3 2.6 7.5 1.0 2.6 2.6 1.22 YJL108C 1.0 0.4 0.5 1.0 4.0 0.6 1.0 0.9 0.40 YJL149W 1.5 1.1 1.9 1.1 9.0 1.4 0.8 1.2 0.28 YJL186W 0.6 0.6 0.4 0.8 2.5 1.0 0.7 0.8 1.07 YNL190W 1.0 1.0 1.3 0.6 2.6 1.3 0.7 0.8 4.72 YNL208W 2.5 0.8 1.7 1.0 2.6 0.9 1.0 1.0 1.55 YNL300W 0.9 0.8 0.7 0.8 3.3 1.0 1.0 0.8 0.39 YNR064C 0.7 0.7 1.6 0.8 6.1 1.4 1.1 1.9 2.17 YOR248W 2.3 0.5 0.4 0.5 8.8 0.3 1.0 0.8 2.47 YPL052W 1.2 1.1 1.6 3.2 3.3 1.1 1.3 1.5 0.88 YPR079W 0.8 1.0 1.3 1.3 2.9 1.9 1.4 1.5 0.42 YAR028W 0.9 0.8 1.4 1.2 0.9 1.5 1.9 2.1 1.40 YDR031W 1.2 0.9 1.3 2.5 0.8 2.4 1.3 2.5 1.23 YDR486C 1.4 1.3 1.7 2.4 1.1 2.6 1.1 1.7 1.18 YER038C 0.6 0.9 2.2 1.3 0.8 1.6 1.2 1.4 0.51 YGL136C 1.4 1.1 1.1 2.3 0.9 1.4 1.3 1.1 0.64 YGR146C 0.9 1.4 1.7 1.3 1.4 1.8 1.3 0.9 0.75 YJL020C 0.6 0.7 1.6 1.2 1.4 0.8 2.0 1.3 0.95 YLR031W 0.7 1.0 1.6 1.5 0.7 1.6 1.2 1.2 0.30 YLR205C 0.4 1.3 1.4 2.4 2.5 2.3 2.0 1.4 0.29 YMR140W 0.7 0.9 1.6 1.2 1.4 2.8 1.4 2.0 0.54 YMR195W 1.1 0.9 0.7 1.3 0.6 2.5 1.6 2.2 1.28 YOR215C 1.6 1.1 1.3 1.7 0.8 3.3 1.3 2.9 2.08 YOR382W 2.5 2.8 1.7 0.4 2.1 4.3 1.9 1.9 0.79 YPL054W 1.9 1.3 1.5 1.4 1.0 1.3 1.5 1.4 0.25 YPR127W 1.6 0.9 1.3 1.4 0.4 2.4 1.3 1.2 0.65 YAR027W 1.7 1.2 2.6 1.3 1.2 2.8 2.0 4.7 2.15 YBL057C 0.9 1.0 1.0 1.6 1.0 1.1 1.2 1.2 1.88 YBR116C 3.1 1.1 2.0 2.7 1.7 9.9 0.9 1.0 0.45 YBR147W 4.0 1.3 1.2 1.1 2.1 6.0 1.3 1.9 0.63 YBR168W 0.8 0.9 1.9 1.8 0.9 1.0 1.1 1.5 0.56 YBR246W 0.8 0.9 1.1 1.3 0.9 1.8 1.4 1.7 0.82 YBR273C 0.6 0.8 2.1 0.9 0.8 0.9 1.4 1.4 1.33 YDR003W 1.8 0.8 1.5 1.2 1.0 1.8 1.4 2.0 0.95 YDR340W 1.4 0.9 1.3 2.0 1.4 1.0 1.1 1.6 1.90 YDR357C 1.1 0.6 1.0 1.4 0.5 2.2 1.3 1.7 0.73 YDR396W 1.0 1.2 0.6 1.4 0.9 1.3 1.1 1.3 0.63 YDR434W 0.8 0.9 1.2 0.9 1.3 0.8 1.2 1.5 1.53 YDR482C 0.8 0.8 1.1 1.0 0.5 1.7 1.6 1.2 0.85 YDR520C 0.6 1.2 1.4 1.0 1.3 0.9 1.1 1.0 0.46 YDR534C 1.7 1.5 1.8 0.7 4.2 1.0 0.6 1.0 0.34 YDR539W 1.3 1.2 1.3 1.1 1.5 1.6 1.2 1.4 0.61 YER044C 1.7 0.7 0.9 1.4 0.7 3.0 1.3 2.1 1.62 YER067W 2.2 1.1 1.2 1.7 0.5 3.5 1.5 3.0 1.57 YER080W 1.2 0.9 1.8 1.1 0.8 1.9 1.2 1.3 0.55 YGL113W 0.7 0.8 1.2 0.9 1.0 1.0 1.5 0.9 0.35 YGL242C 1.4 0.9 1.6 1.6 1.2 1.1 1.5 1.4 1.32 YGR052W 0.6 0.7 1.5 1.3 0.6 7.6 1.8 4.0 0.48 YGR106C 1.2 1.1 1.0 1.2 0.9 1.1 1.0 1.7 4.60 YGR111W 1.6 0.9 2.2 1.5 0.9 2.2 1.1 2.1 0.79 YHL023C 1.0 1.1 1.9 1.0 1.0 1.1 0.9 0.9 0.32 YHL048W 0.9 1.1 1.7 1.0 2.3 2.5 1.9 3.2 4.10 YIL007C 1.2 1.0 1.1 1.7 1.1 1.9 1.2 1.5 0.69 YIR016W 1.4 1.3 1.6 1.3 1.0 2.7 1.9 2.0 0.67 YIR043C 1.4 1.3 2.0 1.4 2.5 2.6 1.4 2.5 3.90 YJL012C 0.7 1.2 1.3 1.0 1.1 0.3 0.9 0.8 1.77 YJL083W 0.3 0.9 0.8 1.1 0.9 0.6 1.4 1.0 0.34 YJL131C 0.3 0.8 1.8 1.5 1.0 2.2 1.3 1.2 0.54 YJR061W 0.8 0.9 0.8 1.5 1.6 1.1 1.3 1.1 0.34 YJR161C 1.7 1.2 2.1 1.0 2.9 2.6 2.1 3.4 3.62 YKL175W 0.8 0.9 1.7 1.0 1.6 1.1 0.9 1.0 1.71 YKR070W 1.6 0.9 1.7 1.2 0.8 2.1 1.0 1.4 0.99 YLL023C 1.6 1.2 1.6 1.1 2.5 2.8 1.6 1.4 1.66 YLR023C 1.1 0.6 1.0 1.1 0.9 0.8 0.7 0.8 0.92 YLR225C 0.8 1.2 1.3 1.4 1.6 0.8 1.2 1.2 1.41 YLR241W 0.7 0.9 2.0 0.9 2.4 1.1 1.4 1.6 1.03 YLR252W 2.5 0.7 1.3 1.3 0.9 2.7 2.2 2.9 0.96 YLR270W 2.8 1.1 2.1 1.3 1.4 2.6 1.4 2.3 1.00 YML030W 1.2 0.7 1.0 1.3 0.6 2.7 1.2 1.3 1.35 YMR148W 1.0 0.5 1.0 1.0 0.7 1.4 1.1 0.9 0.28 YMR181C 1.7 1.4 2.8 1.0 1.4 2.8 1.1 2.0 0.79 YMR298W 1.7 0.9 1.0 2.0 2.0 1.7 1.4 1.6 1.37 YNL011C 1.4 0.6 1.2 1.2 0.8 3.1 1.2 1.8 0.68 YOL129W 0.7 0.8 1.8 1.5 1.0 1.9 2.6 2.4 2.61 YOR042W 0.9 0.8 1.3 1.2 1.1 1.1 1.4 1.1 0.54 YOR052C 0.8 1.0 2.6 1.6 1.2 1.3 1.2 2.3 2.64 YOR137C 0.9 0.8 1.6 0.9 1.4 1.0 1.6 1.5 0.78 YPL156C 0.9 1.5 1.7 1.6 0.8 2.4 1.6 1.9 0.70 YPL186C 3.7 1.0 1.4 2.0 0.7 6.2 1.2 2.9 0.60 YPL216W 0.9 0.9 1.1 1.2 1.0 1.1 1.1 0.9 0.47 YPR098C 1.9 0.9 1.2 1.8 0.9 2.9 2.2 2.2 1.10 YFL062W 2.2 1.1 1.6 1.1 1.6 2.7 2.1 3.0 3.43 YJL217W 4.6 0.7 0.5 0.7 0.8 5.1 1.4 2.5 2.19 YLR126C 1.3 1.4 1.6 1.4 1.4 1.4 1.3 1.2 0.61 YNL249C 1.4 1.0 1.4 1.3 0.9 1.3 1.1 1.1 0.56 YNL336W 0.8 1.1 1.3 1.1 1.9 2.8 2.0 3.1 3.74 YBR074W 0.5 1.0 1.2 1.5 0.8 1.3 1.4 1.0 0.52 YDL248W 1.4 1.2 2.0 0.9 1.8 1.9 1.6 2.4 4.35 YDR105C 1.4 0.9 1.8 1.1 0.9 1.4 1.1 1.4 1.09 YEL075C 0.7 1.1 1.7 1.9 0.8 1.2 1.4 1.1 1.19 YER046W 1.1 1.0 1.0 1.4 0.7 2.7 2.0 1.9 0.53 YER050C 1.4 0.7 1.0 2.1 1.0 2.1 1.0 1.8 1.40 YGL250W 2.4 0.7 1.2 1.0 1.1 2.3 1.2 1.9 0.45 YGR042W 1.6 1.1 1.6 2.2 1.4 2.6 1.3 1.9 0.79 YGR053C 1.6 0.7 1.2 1.7 0.7 2.7 1.5 2.4 0.39 YGR066C 2.6 0.8 1.2 1.9 0.7 2.6 1.0 1.1 0.17 YGR247W 1.1 0.6 0.8 1.0 0.4 1.2 1.0 1.0 0.45 YGR295C 1.1 1.1 1.9 1.0 2.4 2.4 1.6 2.8 4.78 YHL044W 0.7 1.2 1.6 1.7 1.1 3.9 0.8 1.2 0.45 YHR145C 2.0 0.9 1.5 1.8 1.3 1.1 1.3 1.1 1.70 YIL058W 0.0 0.6 1.0 2.0 0.9 2.1 1.4 1.3 0.39 YIL065C 1.1 0.9 1.8 1.7 0.8 2.4 2.1 1.4 0.94 YIL083C 1.2 1.0 1.0 1.0 0.9 1.4 0.9 1.1 0.76 YJL185C 1.2 0.8 1.0 1.4 1.6 2.3 1.0 1.1 0.30 YJL213W 0.7 0.7 1.0 0.8 2.8 3.6 2.1 2.8 0.33 YKR020W 1.0 0.8 1.7 1.4 1.2 2.5 1.3 2.0 0.44 YLL025W 1.4 1.0 1.3 1.0 1.2 1.7 1.0 0.9 0.40 YLR108C 2.6 0.8 1.9 3.4 1.2 2.3 1.0 1.5 0.39 YLR290C 1.5 0.8 1.0 1.3 0.8 3.2 1.3 2.4 1.49 YML068W 0.6 0.4 0.8 1.1 1.1 1.9 1.0 1.3 0.41 YMR178W 1.0 0.9 1.0 1.2 0.9 2.1 1.1 2.3 1.36 YNL122C 1.3 0.7 1.0 1.2 0.6 1.8 1.0 1.4 1.07 YNL285W 1.2 0.6 1.1 1.8 0.9 1.3 1.2 1.3 0.43 YNL293W 0.8 0.7 1.4 1.1 1.2 2.1 1.0 1.4 0.58 YNR061C 1.2 0.9 1.1 1.3 0.9 1.1 1.6 1.1 1.52 YOR220W 1.2 1.2 2.9 0.8 0.7 2.0 3.5 3.4 1.44 YPR077C 0.8 1.0 0.8 1.6 2.9 0.6 1.4 1.2 0.24 YPR147C 1.3 0.9 1.6 1.1 1.4 1.9 1.1 1.3 1.18 YEL041W 3.5 0.9 1.9 2.0 1.4 1.9 1.5 1.9 0.39 YKL187C 3.3 0.9 1.4 1.6 1.2 4.8 0.7 1.2 0.36 YBR285W 4.6 0.5 0.9 1.6 0.4 7.8 2.5 2.3 0.27 YBR292C 1.8 0.4 0.7 1.1 1.0 1.0 0.9 0.9 0.30 YDL123W 4.6 1.1 1.5 0.9 3.3 1.5 1.1 1.0 0.52 YDR056C 2.3 1.2 1.0 2.3 1.1 2.5 1.2 2.0 1.83 YDR132C 3.3 0.9 1.5 1.4 1.2 1.2 1.0 1.3 0.40 YDR154C 3.2 1.0 2.6 1.0 1.8 1.3 1.5 2.0 2.69 YDR295C 1.9 0.7 1.8 1.1 1.4 0.6 0.8 1.0 0.49 YDR494W 1.6 0.8 1.0 1.0 0.6 1.9 1.1 1.3 1.39 YEL072W 1.7 0.9 1.0 2.0 0.5 1.5 0.8 1.1 0.39 YER045C 2.3 0.8 1.2 1.3 1.4 1.6 1.1 1.1 0.34 YER181C 0.1 0.6 1.3 1.0 0.7 0.7 0.7 1.1 0.42 YGL114W 3.2 0.6 1.2 1.1 1.2 1.4 0.9 0.8 0.60 YGL193C 2.1 0.7 1.1 1.0 1.0 1.7 1.1 0.9 0.62 YGL204C 1.9 0.8 1.4 1.8 0.8 1.1 0.9 0.9 0.38 YGL259W 2.7 1.1 1.9 1.1 1.3 4.1 0.9 0.9 0.49 YIL060W 1.9 0.7 0.6 0.9 1.3 1.1 1.2 0.9 1.22 YJL036W 1.7 1.2 2.2 1.5 1.1 2.1 1.4 1.6 0.88 YJR085C 2.9 1.1 1.9 1.9 0.5 2.0 1.4 1.9 2.19 YKR071C 2.3 0.8 1.5 1.6 0.7 0.8 0.9 1.0 1.05 YLR145W 2.4 0.8 0.7 1.6 1.0 2.5 1.0 0.8 0.62 YLR156W 1.9 0.8 1.9 1.0 1.0 1.7 1.1 0.9 0.31 YLR280C 2.1 0.8 1.6 0.5 0.6 1.2 1.2 0.9 0.19 YLR311C 7.8 0.9 0.9 1.6 0.5 1.9 1.3 1.1 0.33 YMR034C 2.1 0.9 1.8 1.4 1.7 1.3 1.8 1.6 0.43 YNL240C 3.4 0.7 1.1 0.8 1.4 0.8 0.8 0.7 0.37 YNL260C 2.5 0.6 0.7 1.4 0.7 1.2 0.9 1.0 0.75 YNR074C 2.7 0.6 1.5 1.7 0.8 0.9 0.9 0.8 0.66 YOL084W 6.1 1.7 6.4 0.9 1.6 6.6 1.3 1.6 0.28 YOL159C 6.6 1.2 1.4 1.8 1.1 2.3 2.0 1.6 0.61 YOR228C 2.8 0.9 1.1 1.0 0.6 3.4 1.0 1.4 0.44 YOR255W 2.0 0.7 1.6 1.3 4.9 1.2 1.0 1.0 0.19 YBR047W 3.4 0.8 1.7 1.0 0.8 1.1 1.3 1.0 0.25 YER124C 1.5 0.6 0.7 0.5 0.5 1.5 0.9 1.1 2.22 YKR007W 1.3 0.8 0.9 1.2 1.2 1.1 0.8 0.9 0.73 YOR007C 1.8 0.7 0.7 0.8 1.3 1.0 1.2 0.8 2.26 YBL065W 1.3 0.7 1.8 1.9 3.1 0.9 1.1 0.9 0.15 YDL113C 1.1 1.3 1.5 1.2 1.2 1.7 1.2 1.5 0.58 YDR018C 1.4 1.1 1.8 1.7 1.0 2.6 0.9 1.2 0.22 YDR202C 1.3 0.8 1.2 2.0 0.5 2.8 1.0 1.6 0.79 YDR223W 1.4 1.0 1.5 1.2 1.2 3.5 0.9 1.0 0.29 YDR350C 0.9 0.9 1.0 1.1 1.6 1.3 1.4 1.2 0.53 YDR374C 1.4 1.0 2.5 4.0 2.0 1.3 1.0 1.0 0.36 YDR512C 1.8 1.1 1.9 2.7 1.1 3.0 1.3 2.0 0.82 YFR017C 3.1 1.8 1.7 1.3 1.4 3.7 0.9 1.1 0.49 YGL046W 1.5 1.1 1.6 0.9 2.0 1.2 1.5 1.3 0.42 YGL067W 1.7 0.9 3.7 1.6 0.7 1.0 0.9 1.1 0.63 YGL098W 1.3 0.8 0.8 1.1 0.7 1.3 1.1 1.5 0.77 YGL117W 1.4 1.5 1.4 2.0 1.4 0.6 2.1 1.1 1.05 YGL146C 1.3 0.9 1.1 1.2 1.1 2.2 1.0 1.0 0.43 YGR011W 2.3 0.8 1.6 3.9 1.8 1.6 0.9 1.0 0.40 YGR153W 1.0 0.7 1.1 1.9 1.3 1.1 1.3 1.7 0.39 YGR223C 1.9 0.8 1.8 1.6 1.2 1.8 1.1 1.8 0.66 YHR116W 0.9 0.8 1.9 1.4 1.2 1.9 0.9 1.5 0.60 YIL097W 1.4 1.1 1.4 1.4 1.2 2.1 1.1 1.7 0.52 YKL133C 1.4 1.3 1.4 1.6 1.7 3.8 1.2 2.4 0.35 YKL162C 1.6 1.1 1.1 1.9 1.6 2.0 0.8 1.1 0.25 YLL062C 1.7 0.6 1.4 1.7 1.6 1.0 0.9 0.9 0.29 YLR247C 1.6 1.0 1.8 1.0 1.4 1.4 1.2 1.3 0.48 YLR267W 1.7 0.8 1.5 2.3 0.7 3.6 1.2 2.8 0.24 YMR041C 1.6 1.0 1.1 0.6 0.5 0.3 0.8 0.4 0.84 YMR253C 1.0 0.5 1.2 1.3 0.9 1.3 1.2 1.4 0.42 YOR225W 1.2 0.5 0.6 2.2 0.7 0.6 0.9 0.9 0.26 YPL166W 1.4 0.8 1.4 0.8 1.2 2.3 1.1 1.6 0.39 YPL202C 1.0 0.7 1.1 0.9 1.0 1.2 1.1 1.0 0.56 YBR101C 1.3 0.7 1.6 0.7 0.5 0.3 0.9 1.0 1.83 YBR269C 1.2 1.0 1.3 1.4 0.4 1.6 1.5 1.6 0.58 YBR280C 1.3 1.3 2.8 1.3 1.0 3.2 1.1 1.7 0.33 YDL234C 1.5 0.9 3.5 0.7 1.0 2.5 2.3 3.6 0.94 YDL242W 1.3 1.0 1.0 1.0 1.2 1.3 0.9 1.0 0.38 YDR531W 1.3 0.9 1.4 1.2 0.9 1.2 1.5 1.2 1.32 YFR042W 1.7 1.1 1.9 1.7 1.4 1.4 1.7 1.7 1.17 YFR046C 1.0 0.9 1.1 1.4 0.9 1.3 1.2 1.2 0.29 YGL227W 1.1 0.8 1.0 1.3 0.9 1.5 1.1 1.3 0.59 YGR089W 0.9 0.7 0.8 1.1 0.8 0.9 0.9 1.1 0.50 YGR134W 0.9 0.7 1.5 1.1 1.1 0.7 0.9 0.8 0.33 YHR017W 1.5 1.0 1.2 1.2 0.8 2.5 1.1 1.7 0.90 YIL152W 0.9 1.1 1.4 1.7 0.9 1.5 1.1 1.0 0.81 YIL164C 1.0 1.0 1.8 2.0 0.9 2.5 1.4 1.4 0.54 YJR056C 0.8 0.8 0.9 1.4 1.6 1.3 0.9 1.1 0.44 YJR072C 0.9 1.0 1.1 1.2 0.6 0.9 0.8 0.8 0.78 YKL034W 1.2 1.0 1.9 1.0 1.6 1.5 1.3 1.2 0.41 YKR012C 0.8 0.7 1.5 1.4 1.2 0.9 1.0 0.9 0.61 YLR064W 1.6 0.7 1.6 1.4 1.5 1.0 0.9 1.0 1.49 YLR364W 1.5 0.7 1.0 3.0 1.9 1.0 1.0 0.9 0.37 YLR421C 1.2 0.9 1.6 1.6 1.6 1.9 1.2 1.8 2.07 YML118W 1.3 0.9 1.7 1.0 2.2 1.6 1.5 1.5 0.26 YMR114C 1.0 0.9 1.1 1.5 1.2 3.0 1.0 1.3 0.62 YMR115W 1.1 1.0 1.3 1.3 1.2 1.1 1.0 1.2 0.61 YMR258C 1.4 0.9 1.6 1.0 0.6 1.2 1.1 1.3 0.60 YNL181W 1.2 0.8 1.8 1.9 1.0 1.0 0.8 1.3 0.86 YNL191W 1.0 0.5 0.6 1.0 1.0 0.6 0.5 0.6 0.45 YNL212W 1.3 0.8 1.3 1.0 0.9 1.3 0.9 1.2 0.67 YNL265C 0.9 0.8 2.0 1.9 0.6 1.7 0.9 1.8 0.85 YOR088W 0.8 0.6 0.4 0.4 0.8 0.4 0.7 0.7 3.56 YOR155C 1.6 0.5 1.5 0.9 0.8 0.9 0.46 YPL151C 0.9 0.8 1.4 0.9 1.8 0.9 0.8 1.0 0.51 YPL249C 0.9 0.9 1.8 1.0 1.0 1.0 0.8 1.2 0.36 YPL260W 1.0 0.8 1.4 1.1 1.3 1.2 0.8 1.3 0.82 YPR061C 1.6 0.8 1.1 1.7 0.4 2.7 1.1 0.9 0.40 YPR093C 1.2 0.9 1.4 1.1 0.8 1.4 1.4 1.1 0.39 YPR158W 1.5 0.6 1.6 1.1 0.9 0.6 0.9 0.7 0.96 YPR169W 1.0 0.5 1.0 1.0 0.9 1.4 1.1 1.1 0.86 YPR174C 0.7 1.1 1.4 0.9 1.2 0.4 1.4 0.9 0.55 YAL014C 1.7 1.2 1.5 1.8 2.3 0.9 1.1 1.1 0.56 YAL017W 0.7 1.0 2.2 1.1 1.0 1.3 1.0 1.2 0.79 YAL049C 1.0 1.1 1.6 2.0 1.4 2.9 1.6 1.8 1.13 YBR013C 1.2 1.2 2.0 2.5 1.1 1.5 1.4 1.1 0.68 YBR051W 0.1 0.7 1.2 1.0 0.8 1.2 1.1 0.8 0.40 YBR063C 0.6 1.1 1.7 1.7 1.6 1.0 1.2 1.2 0.38 YBR129C 1.4 1.0 1.3 1.6 0.9 1.7 1.0 1.5 1.25 YBR255W 1.5 0.7 1.4 1.1 1.0 1.5 1.0 1.0 0.27 YBR281C 1.4 0.5 1.2 0.9 1.0 0.8 0.7 0.8 0.44 YCL044C 1.1 0.9 1.7 1.0 4.4 0.8 0.9 0.6 0.21 YDL089W 2.0 0.9 1.9 1.2 1.6 1.3 1.0 1.1 0.45 YDL173W 1.2 1.1 1.7 2.1 1.1 1.3 1.3 1.8 1.19 YDL193W 1.1 1.1 1.4 1.1 1.2 1.8 0.9 1.4 0.93 YDL233W 0.7 0.9 1.8 1.1 1.3 0.9 1.1 1.4 0.33 YDR071C 1.4 0.9 1.3 2.0 0.9 1.2 0.9 1.6 3.08 YDR078C 1.1 0.7 1.1 1.8 0.5 1.3 0.9 1.2 0.53 YDR109C 0.9 1.0 1.4 1.0 1.7 1.5 1.2 0.9 0.38 YDR140W 1.7 1.1 2.0 3.2 0.9 1.9 1.3 1.3 0.78 YDR221W 0.7 0.6 1.0 1.0 1.0 1.0 1.1 1.0 0.34 YDR271C 0.6 0.7 1.5 1.4 1.3 0.6 1.2 0.9 0.32 YDR316W 1.3 0.6 0.6 0.7 1.3 0.3 0.6 0.5 0.69 YDR338C 1.9 0.8 1.3 1.0 0.8 0.8 0.9 1.0 0.40 YDR421W 1.0 0.7 0.6 1.2 1.9 1.0 0.7 0.8 0.42 YDR425W 0.9 1.1 1.4 1.3 1.3 1.1 1.2 1.2 0.31 YDR485C 0.9 0.9 1.2 1.1 1.3 1.5 0.8 1.0 0.59 YDR504C 1.2 0.7 2.2 1.3 1.2 1.2 1.2 1.2 0.70 YEL044W 1.6 0.6 1.3 0.6 0.6 0.7 1.4 1.0 0.93 YER092W 0.9 0.9 1.2 1.2 1.0 1.9 1.4 1.7 1.13 YER182W 1.5 1.0 0.9 1.9 0.5 3.6 0.8 1.2 0.87 YFL042C 5.4 0.9 1.7 1.2 1.1 1.0 1.1 1.2 0.43 YFR056C 1.3 0.5 0.3 0.6 0.9 0.5 1.1 0.8 0.59 YGL041C 0.6 0.6 1.0 1.2 0.7 0.8 1.0 1.1 0.51 YGL045W 1.2 1.1 1.3 1.1 1.5 3.4 1.3 1.2 0.47 YGL057C 1.3 1.1 1.3 1.5 0.7 1.2 0.9 1.1 0.56 YGL183C 0.8 0.9 1.5 1.7 1.7 0.6 1.4 1.0 0.18 YGL223C 1.3 0.9 1.7 0.9 0.7 1.1 0.8 1.0 0.60 YGR156W 0.5 1.2 1.8 1.6 1.3 0.5 0.8 0.8 0.26 YGR198W 1.0 0.7 1.3 0.8 0.9 1.2 1.1 1.0 0.87 YGR210C 1.0 0.6 1.0 0.8 1.3 0.7 1.1 0.7 0.56 YGR211W 0.8 0.6 0.8 0.4 0.5 0.3 0.5 0.5 1.99 YGR237C 1.6 0.8 1.6 0.6 1.1 1.2 0.9 1.0 0.50 YGR250C 1.6 0.6 1.7 1.3 1.2 1.2 1.3 2.1 1.21 YGR266W 1.2 0.6 1.1 0.8 1.1 1.3 0.7 1.0 0.59 YGR277C 1.2 0.9 1.6 1.5 0.9 1.0 1.3 1.1 0.81 YHL021C 1.4 1.1 2.6 1.1 1.2 2.4 1.3 3.6 1.27 YHL037C 1.0 0.6 1.0 0.9 0.8 0.7 0.9 0.9 0.28 YHR083W 1.3 0.9 1.1 1.6 1.3 2.4 0.8 1.0 0.90 YHR134W 0.7 1.0 1.2 1.6 1.0 1.2 1.3 1.3 0.81 YHR180W 1.4 0.7 1.3 1.5 0.8 1.3 0.8 1.0 0.36 YIL108W 1.2 0.7 1.3 1.0 1.8 0.7 1.2 0.7 0.51 YIL165C 1.1 0.9 1.5 1.3 0.8 1.9 1.4 1.3 0.74 YJL032W 1.8 0.5 1.4 1.6 1.0 1.2 1.1 1.1 0.33 YJL049W 1.5 0.8 0.9 1.8 0.8 1.6 0.9 1.1 0.75 YJR044C 1.9 0.7 2.0 1.3 1.6 2.7 1.8 1.6 1.18 YKL059C 0.9 0.9 1.3 1.1 1.1 0.8 1.1 0.9 0.53 YKL090W 2.3 0.6 0.8 1.4 0.8 1.6 0.7 1.0 0.37 YKL094W 1.3 0.9 1.7 1.3 1.0 2.0 1.2 1.9 1.60 YLR097C 1.7 0.8 1.1 1.7 0.9 2.5 1.1 1.7 0.76 YLR226W 0.8 0.7 0.7 1.1 1.3 0.9 1.1 1.0 0.56 YLR392C 1.4 0.6 1.4 1.1 0.5 2.1 0.8 1.6 0.46 YLR427W 0.8 0.9 2.5 0.8 0.8 1.3 1.0 1.0 0.49 YML013W 1.1 0.9 1.2 1.1 2.2 1.3 1.1 0.8 0.27 YML029W 1.2 1.1 2.0 1.6 0.8 1.1 1.2 1.0 0.46 YML041C 0.9 0.8 1.2 2.2 1.0 1.4 1.3 1.3 0.59 YML079W 1.2 1.1 1.6 1.4 0.3 2.0 1.4 1.4 1.18 YMR068W 1.1 0.7 1.4 1.1 2.2 0.8 1.3 1.1 0.24 YMR160W 1.0 1.0 1.6 1.1 1.5 1.4 0.9 1.3 0.37 YNL026W 1.1 0.9 1.7 0.8 0.8 1.5 1.0 1.4 0.86 YNL063W 1.1 1.0 1.5 1.1 0.7 1.8 0.9 1.0 0.54 YNL176C 1.2 0.6 0.6 0.9 0.8 1.3 0.6 0.8 0.66 YNL194C 17.1 0.5 1.5 3.0 0.5 4.3 0.8 2.4 0.34 YNL253W 0.8 0.8 1.1 1.4 0.5 1.1 1.1 1.2 0.54 YNL276C 0.7 0.9 1.5 1.5 0.5 0.8 1.1 0.8 0.22 YNR051C 1.5 0.9 2.1 1.0 1.2 0.6 0.7 0.8 1.58 YOR022C 1.7 0.8 1.7 1.0 0.8 1.8 1.1 1.1 0.36 YOR087W 1.3 0.8 1.2 0.9 0.8 1.2 0.8 1.1 0.61 YOR138C 0.7 0.9 1.8 0.9 1.0 1.1 1.1 1.1 0.47 YOR267C 0.4 0.9 1.4 0.9 1.3 0.8 1.3 1.0 0.58 YPL005W 1.1 0.7 1.2 1.0 1.2 1.6 1.2 1.1 0.32 YPL150W 1.1 1.0 2.1 1.0 1.1 1.2 1.4 1.1 0.47 YPL152W 1.4 0.9 1.4 1.2 2.3 1.4 1.2 1.9 0.42 YPL168W 0.7 0.7 1.0 1.0 0.8 1.3 1.1 1.2 0.41 YPL180W 1.0 0.8 1.5 1.0 0.7 1.0 1.0 0.9 0.30 YPL188W 1.0 0.6 0.9 1.4 0.8 1.7 0.7 0.9 0.55 YPR049C 0.9 0.9 1.6 1.4 1.5 1.7 1.0 1.1 0.34 YPR148C 0.9 1.2 1.2 1.1 1.7 1.7 0.9 2.0 1.25 YPR172W 1.9 0.8 1.3 1.6 1.5 1.9 1.1 1.4 0.45 YAL018C 0.1 0.9 1.3 1.0 6.9 1.1 0.9 0.9 0.21 YAR064W 0.7 0.8 1.1 1.1 1.9 1.0 0.9 0.9 0.30 YBR012C 0.7 1.0 2.1 0.9 1.1 1.3 1.4 1.2 0.46 YBR287W 2.0 1.2 3.4 0.8 1.3 1.6 3.2 1.9 2.73 YDR250C 0.6 0.8 1.2 0.9 0.7 1.7 0.9 0.9 0.32 YJL037W 1.6 0.8 1.1 2.0 1.6 1.0 1.3 0.9 0.26 YNL058C 1.0 1.0 0.6 0.8 2.2 0.9 0.8 1.0 0.60 YJR030C 0.8 0.9 0.7 1.0 0.8 0.9 0.7 0.9 0.27 YKR040C 0.8 0.8 0.6 3.8 1.1 1.2 0.7 0.8 0.53 YDR128W 0.3 0.6 1.1 1.0 1.4 1.3 0.9 0.9 0.40 YGR139W 0.9 0.5 0.4 0.9 2.3 0.8 1.0 0.8 0.22 YOR253W 0.9 0.7 0.5 1.3 1.1 0.9 0.9 0.9 1.01 YOL026C 1.2 0.9 1.2 1.3 0.9 2.4 2.1 1.4 0.65 YDR278C 0.4 0.6 0.7 0.9 0.7 0.5 0.7 0.8 0.78 YHR095W 1.3 0.6 0.7 0.9 0.8 0.9 0.8 0.7 0.67 YCL042W 3.2 7.5 0.8 1.94 YNL200C 3.1 0.9 1.1 0.6 0.8 0.9 1.2 0.9 1.40 YPL221W 1.0 0.8 1.0 0.8 1.0 1.2 1.5 1.2 1.51 YLR415C 0.8 0.8 1.0 0.8 1.0 1.9 0.8 1.0 0.19 YOR325W 0.6 0.9 0.6 1.3 0.7 1.4 0.8 1.0 0.19 YGL088W 0.8 0.6 0.7 1.4 0.4 0.3 0.5 0.7 1.80 YDR090C 0.7 0.6 0.8 0.9 1.1 0.9 1.1 1.1 0.79 YMR071C 1.2 0.7 1.3 1.2 0.8 1.4 1.2 1.9 2.39 YGR293C 0.6 1.0 0.7 1.0 0.7 0.9 0.8 0.9 0.23 YJL017W 1.4 1.3 1.5 1.0 1.1 0.6 1.0 1.0 0.85 YIL127C 0.9 0.7 0.4 1.3 0.7 0.2 0.7 0.6 1.57 YDR281C 0.8 0.9 0.7 1.2 0.3 0.6 1.5 1.2 1.56 YDR366C 1.7 0.6 0.8 1.4 1.4 1.0 1.2 0.9 1.14 YFR026C 0.8 0.6 1.1 1.0 2.3 2.2 1.1 1.1 0.39 YAR047C 1.1 0.9 1.4 1.3 0.5 1.0 1.7 1.0 0.35 YHL006C 0.7 1.0 1.1 1.1 0.6 0.9 1.1 1.0 0.37 YPL225W 0.9 0.7 0.8 1.4 0.9 1.8 1.0 1.7 2.87 YBR124W 0.4 0.9 0.9 1.0 1.0 0.8 0.9 0.9 0.29 YBL044W 0.6 0.9 0.7 0.9 0.7 0.6 0.8 0.8 0.39 YCL056C 1.5 1.0 1.3 2.2 1.7 2.3 1.2 1.5 0.82 YCR007C 1.1 0.8 1.5 1.7 0.8 1.7 2.6 2.1 0.39 YPR146C 1.4 0.8 1.3 0.9 0.9 1.3 1.0 1.1 0.80 YKL097C 0.6 0.6 0.9 1.0 0.8 0.5 1.1 0.5 0.21 YBR066C 1.2 0.7 0.6 1.1 0.4 3.2 1.2 1.2 0.83 YLR338W 0.9 0.6 1.2 0.8 1.5 0.9 0.8 0.6 0.33 YBR162C 0.8 0.7 0.7 0.5 1.9 0.4 1.2 1.3 3.96 YDL046W 2.6 1.0 1.5 1.2 2.3 2.6 1.2 1.6 1.94 YDR133C 1.3 0.3 0.1 0.6 0.6 1.1 0.6 0.9 4.02 YGR038W 1.4 1.0 1.2 1.4 1.1 1.3 1.1 1.1 1.27 YGR243W 1.7 1.2 1.1 1.9 0.8 2.8 2.1 4.4 1.11 YHR105W 0.7 0.7 1.4 1.2 0.9 1.8 1.0 0.9 0.32 YHR181W 1.3 0.8 0.7 1.6 1.4 1.5 0.9 0.9 1.40 YJL097W 1.5 1.0 0.7 1.0 1.1 1.2 1.2 1.1 1.69 YKL051W 1.8 0.8 1.2 0.7 1.5 0.9 1.5 1.4 1.07 YKL100C 1.6 0.9 1.3 1.0 1.7 2.0 0.7 1.5 1.14 YLR339C 1.6 0.6 0.1 0.5 1.0 0.5 0.7 0.6 1.37 YOL030W 1.3 0.9 1.7 0.6 0.9 0.7 0.9 1.0 1.93 YPR150W 0.9 0.6 1.4 1.4 0.9 1.8 0.9 1.0 0.31 YBL100C 0.9 0.7 0.9 0.9 1.0 0.5 0.8 0.8 0.58 YBR096W 1.2 0.9 1.9 1.7 1.1 1.1 1.1 1.5 1.43 YBR100W 0.2 0.7 1.2 1.2 1.3 1.2 0.8 0.9 0.35 YCL058C 1.0 1.0 0.9 1.9 1.2 0.8 1.4 0.9 0.72 YCR030C 1.1 0.9 1.7 0.8 1.3 1.0 1.2 1.0 0.63 YDL015C 0.8 1.0 0.9 1.1 1.1 2.1 1.0 1.5 2.99 YDL023C 3.5 0.9 1.4 0.7 0.6 0.9 0.8 1.1 0.78 YDL086W 1.4 0.8 1.7 0.9 0.9 1.1 0.8 0.8 0.80 YDR233C 3.7 1.3 0.5 0.9 1.5 2.8 0.9 0.9 3.47 YDR359C 0.5 1.0 1.1 1.3 1.4 0.9 0.8 0.9 0.34 YEL033W 1.2 0.6 0.4 1.0 0.6 0.9 0.9 0.9 2.96 YGR022C 0.4 0.7 1.2 1.1 0.7 0.6 0.9 0.8 0.50 YGR026W 1.3 0.5 0.6 1.0 1.2 1.4 1.0 1.2 2.19 YGR107W 0.6 0.6 0.9 1.0 1.1 0.8 1.2 0.8 0.43 YHL005C 0.7 0.7 1.0 0.7 0.7 1.0 0.8 0.33 YHR126C 1.9 1.0 0.8 0.8 1.4 1.7 1.1 1.3 1.31 YHR143W 1.2 0.5 0.5 0.8 0.3 0.9 0.9 0.7 3.58 YIL157C 1.3 0.8 1.0 1.0 0.5 1.8 1.1 1.5 1.46 YIR041W 1.2 1.3 1.1 1.1 1.3 1.3 1.1 0.9 0.66 YJL016W 1.3 0.9 1.3 1.6 1.1 2.5 1.2 1.5 0.88 YJR018W 0.9 0.8 1.5 0.9 1.4 0.8 1.0 0.7 0.35 YKL147C 0.3 0.9 1.0 1.0 0.7 1.1 0.9 0.9 0.28 YKL169C 0.7 1.0 1.3 0.8 2.6 0.9 1.1 0.45 YKR033C 0.3 0.4 0.9 0.9 1.1 0.6 1.0 0.9 0.28 YLL064C 1.0 1.1 1.3 1.1 1.2 1.6 1.2 1.0 0.68 YLR041W 1.1 0.4 0.3 0.5 1.3 0.5 0.7 0.9 0.69 YLR177W 0.9 1.1 1.5 1.0 0.5 1.3 1.1 1.5 1.25 YMR007W 0.9 0.8 1.3 1.2 1.8 1.1 2.5 1.0 0.30 YMR156C 1.1 0.7 1.0 1.2 0.7 1.3 1.2 1.1 0.40 YMR215W 1.1 0.4 0.2 0.5 0.7 0.2 0.7 0.7 1.59 YNL195C 2.9 0.6 1.6 1.5 1.4 6.4 0.8 0.9 0.32 YOL073C 1.7 0.8 1.6 0.8 1.6 1.7 1.2 1.2 0.54 YOR129C 1.1 0.6 0.2 0.5 0.6 0.3 0.6 0.4 5.22 YOR161C 4.6 0.5 0.7 0.9 1.4 2.0 0.7 1.2 0.82 YPL004C 1.7 0.9 1.3 1.0 1.1 2.0 1.2 2.2 4.52 YPL246C 1.1 0.8 0.9 0.7 1.2 1.1 1.2 0.9 0.98 YPL272C 1.1 0.7 1.1 1.1 0.6 2.5 0.9 1.2 0.25 YPR063C 1.0 0.7 0.8 1.0 1.0 1.2 1.0 0.9 1.41 YDL129W 0.6 0.9 0.5 0.8 0.5 1.4 0.6 0.8 0.69 YDR066C 0.6 0.8 1.4 1.3 0.9 1.4 1.1 1.1 0.57 YGL059W 1.4 1.0 2.0 1.2 1.6 1.7 1.4 1.4 0.49 YNL144C 1.7 1.4 1.0 1.1 0.1 1.7 2.4 2.8 0.51 YAL037W 0.5 0.8 1.1 1.2 0.8 0.6 0.9 0.9 0.55 YAR023C 1.0 1.2 1.1 1.0 3.1 1.6 0.9 1.1 0.62 YCR015C 1.1 0.9 0.6 1.2 0.9 1.1 1.1 1.2 0.58 YCR043C 1.0 0.6 0.8 1.6 1.2 0.8 1.0 1.1 1.25 YDL146W 1.4 1.0 1.4 1.0 1.7 1.8 1.0 1.2 0.62 YDR057W 1.0 0.7 0.9 1.2 1.1 1.7 0.7 1.1 0.70 YDR222W 1.0 0.5 0.8 1.3 0.5 0.6 0.7 0.8 0.52 YDR286C 1.1 0.9 1.4 1.3 0.8 2.1 1.1 1.4 0.90 YDR438W 1.1 0.8 1.2 1.3 1.0 1.2 1.6 1.2 0.48 YDR479C 1.0 1.0 1.2 1.4 1.6 2.1 1.1 1.5 0.51 YEL057C 0.7 0.8 1.5 1.5 1.0 1.8 0.9 1.0 0.44 YEL073C 1.1 0.5 1.0 1.1 2.8 1.0 1.3 0.8 0.38 YER084W 0.8 0.7 0.9 2.6 1.5 0.8 0.9 0.30 YER121W 1.2 0.7 0.6 1.3 0.9 4.6 1.2 1.8 0.73 YER189W 0.7 0.8 0.7 0.9 0.9 0.8 0.8 0.8 0.43 YFL017C 1.1 1.0 0.7 1.1 0.6 1.8 1.5 1.8 1.21 YFL046W 1.3 0.8 0.7 1.3 1.0 1.1 1.4 1.6 0.68 YFR008W 0.7 0.9 0.8 1.1 0.8 1.5 1.0 1.0 1.26 YGL214W 0.4 0.8 0.6 1.1 0.9 0.8 1.0 0.8 0.61 YGL218W 0.1 0.8 1.3 0.9 1.1 0.7 1.0 1.0 0.53 YGR021W 0.6 0.9 0.9 1.2 0.8 2.1 1.0 1.0 0.58 YGR024C 1.0 0.7 0.5 1.4 1.0 1.2 0.8 1.3 1.61 YGR064W 1.7 0.8 0.9 2.1 1.0 1.3 0.8 0.9 0.50 YGR182C 0.9 0.7 0.7 2.2 0.4 2.0 1.0 1.7 1.95 YGR236C 1.0 0.9 1.2 1.2 0.7 7.9 1.5 1.9 0.30 YHL042W 0.7 0.6 1.3 1.2 1.1 1.9 1.1 0.9 0.37 YIL012W 0.9 0.6 0.4 1.1 1.1 0.9 1.0 0.9 0.28 YIL028W 1.1 0.5 1.0 1.1 0.9 1.1 1.3 1.0 0.27 YIL057C 0.8 0.6 0.9 1.5 0.8 11.1 1.1 3.6 0.26 YIL089W 0.7 0.6 0.7 1.4 0.6 1.3 1.4 1.3 0.31 YIL102C 0.6 0.7 1.0 0.8 0.6 1.2 1.0 0.18 YIL113W 2.5 0.8 1.3 1.2 0.9 1.6 1.4 1.3 0.48 YIL122W 2.1 1.0 0.7 1.0 1.6 1.4 0.9 0.9 0.35 YJL100W 1.5 0.9 1.4 1.2 1.2 1.4 1.5 1.1 0.38 YJL169W 0.4 0.5 0.7 1.0 0.9 0.6 1.1 0.9 0.35 YJL199C 1.0 0.8 0.9 1.9 0.9 3.7 1.0 1.0 0.59 YJR039W 1.8 0.7 1.5 0.6 1.2 1.5 1.3 1.3 0.24 YJR101W 1.2 0.5 0.5 0.9 0.5 1.2 1.0 1.1 2.04 YKL061W 1.1 0.7 0.8 1.2 0.6 1.5 1.3 1.6 0.92 YKL121W 1.6 0.8 1.0 1.2 0.8 1.6 1.6 1.1 0.31 YKL160W 1.4 0.9 1.6 1.5 0.8 1.6 1.5 2.2 2.19 YLR016C 1.0 0.7 0.8 0.9 0.7 1.3 1.0 1.3 1.15 YLR030W 0.2 0.8 1.5 1.2 0.6 2.1 1.0 1.0 0.29 YLR036C 0.8 0.7 0.7 1.3 0.6 1.4 1.0 1.4 1.07 YLR112W 0.5 0.5 0.7 0.8 0.4 0.4 1.0 0.8 0.39 YLR125W 1.1 0.5 0.8 1.3 0.7 1.6 1.2 1.2 0.29 YLR128W 1.4 0.7 1.2 1.4 0.9 1.5 1.2 1.2 0.25 YLR204W 1.6 0.8 1.1 1.8 1.0 2.5 1.2 1.3 1.26 YLR211C 0.8 0.7 1.1 1.2 3.6 1.9 1.3 1.3 0.35 YLR257W 1.2 1.0 1.0 0.9 1.0 1.7 1.8 2.6 5.20 YLR326W 6.6 0.5 0.4 1.1 0.7 0.9 0.8 1.0 0.33 YLR334C 0.8 0.8 0.9 2.2 2.5 0.7 0.8 1.0 0.30 YLR408C 0.7 0.8 1.1 2.1 0.9 1.1 1.2 1.2 0.79 YLR414C 1.2 0.6 1.0 1.0 2.1 0.9 3.9 3.6 2.21 YLR444C 1.1 0.6 0.5 1.1 1.3 0.7 0.9 0.9 0.50 YML050W 1.2 0.8 0.9 1.9 1.0 1.5 0.8 1.1 0.42 YML107C 0.9 0.7 0.6 1.3 1.0 1.3 1.2 1.5 0.67 YMR031C 0.8 0.7 1.0 1.0 0.7 1.6 0.9 1.3 1.26 YMR204C 0.7 0.7 1.1 1.2 1.5 1.1 0.9 1.1 0.31 YMR206W 1.8 1.0 1.2 1.4 0.3 2.2 1.0 1.2 0.17 YNL010W 1.1 0.9 0.7 1.2 0.9 1.2 1.0 1.7 4.53 YNL127W 1.0 1.0 1.7 1.0 1.5 1.4 0.9 1.4 0.36 YNL217W 0.7 1.0 1.0 0.9 0.5 1.0 1.3 2.1 2.35 YOL118C 1.4 0.6 1.7 3.0 1.0 0.5 0.9 1.0 0.24 YOR053W 1.3 0.6 0.9 1.2 1.0 1.3 1.2 1.2 0.77 YOR352W 1.1 1.0 1.2 1.3 0.7 2.5 1.3 1.7 0.59 YOR394W 1.9 0.9 1.3 0.9 0.9 1.7 1.6 1.1 0.51 YPL033C 0.7 0.6 0.7 1.1 0.8 0.4 0.9 0.8 0.23 YPL066W 1.0 1.1 0.9 0.7 0.7 1.2 1.3 1.3 0.77 YPR014C 0.5 0.7 0.7 1.0 0.9 0.8 0.9 1.1 0.29 YBR005W 0.8 1.7 1.9 0.9 1.1 1.7 2.9 4.6 1.00 YFL027C 1.3 0.6 1.1 0.3 1.4 1.2 5.1 5.2 1.74 YGL080W 0.8 1.0 0.7 1.6 0.9 1.7 1.3 2.9 1.70 YMR252C 1.4 0.8 1.1 1.1 1.1 2.1 1.5 2.2 0.86 YOR385W 1.2 0.6 2.8 0.8 0.8 1.2 4.6 5.9 1.17 YAR033W 1.5 0.9 1.5 1.3 0.9 2.0 1.1 3.0 1.15 YBR151W 0.9 0.9 1.1 0.8 1.0 3.0 1.4 2.4 1.83 YHR162W 1.3 1.2 1.5 2.0 1.1 1.4 1.3 2.7 3.64 YLR165C 1.4 0.9 1.2 1.4 0.5 1.6 1.1 2.1 0.78 YNL157W 1.3 0.9 1.6 1.5 1.0 1.0 1.9 2.3 1.41 YOL002C 0.8 1.1 0.2 0.5 0.6 1.7 1.5 2.1 5.33 YPL233W 0.9 0.6 1.0 1.0 0.4 1.0 1.9 1.9 0.48 YGR149W 1.8 1.2 2.6 1.0 2.4 1.3 2.0 1.7 0.71 YNL043C 0.7 0.9 2.1 1.2 1.6 0.8 2.7 1.6 0.68 YPL067C 0.9 1.4 0.9 0.7 1.5 1.1 2.9 1.7 0.40 YPL170W 1.1 0.9 1.1 1.4 1.2 1.6 2.2 1.4 1.05 YGL051W 1.4 1.0 1.5 1.2 0.8 2.6 1.4 1.9 1.06 YIL112W 1.4 1.2 1.1 1.3 1.8 2.4 1.2 1.3 0.45 YLR052W 1.1 1.0 0.8 1.2 1.0 2.4 0.7 0.9 0.77 YNL203C 1.1 0.9 1.2 2.7 1.2 5.6 1.3 1.7 0.21 YNR014W 4.4 0.9 1.5 4.9 1.0 2.4 1.1 1.0 0.31 YAL028W 1.0 1.0 1.5 1.6 2.2 1.7 1.0 1.0 0.30 YBL095W 1.2 0.8 1.0 1.0 0.4 2.2 1.3 1.9 0.72 YBR157C 0.6 0.6 0.5 0.9 0.2 1.9 1.3 0.8 0.69 YDL091C 1.5 1.0 1.3 1.5 1.9 2.4 1.1 1.6 0.47 YDL216C 0.7 0.9 1.2 1.1 1.0 1.8 1.0 1.6 0.42 YDR067C 0.9 0.9 1.2 1.5 1.5 2.4 1.3 1.4 0.76 YDR186C 0.7 1.1 1.1 0.8 0.8 2.3 1.1 0.9 0.50 YDR196C 1.3 0.7 1.2 1.0 0.7 2.7 1.2 1.9 1.54 YDR262W 1.6 0.8 0.9 1.7 1.5 3.8 1.0 1.4 1.11 YDR306C 2.1 0.9 1.2 1.1 1.2 2.4 1.0 1.5 0.77 YDR319C 1.3 1.0 1.3 0.8 2.0 2.1 2.2 1.23 YER188W 1.2 0.9 1.1 1.1 0.3 2.5 1.0 1.1 0.61 YGL004C 1.0 0.8 1.3 0.9 0.6 2.2 1.1 1.4 0.48 YGR141W 0.6 0.6 1.0 0.7 2.6 2.1 1.1 1.3 0.65 YHR080C 0.7 1.2 2.0 0.9 0.9 2.3 1.1 1.3 0.49 YHR097C 0.7 0.8 1.3 0.9 2.7 2.0 1.7 1.4 0.24 YIL077C 1.3 1.6 1.3 1.3 0.9 2.4 1.3 1.1 0.75 YJL046W 4.2 0.9 1.3 1.3 1.0 2.5 1.0 1.3 0.68 YLL005C 0.9 0.8 1.1 1.7 1.0 2.1 1.1 1.2 0.44 YLR151C 1.1 0.5 0.7 1.3 0.7 2.4 1.0 1.4 0.30 YLR271W 1.3 0.8 1.2 1.2 1.0 3.0 1.5 1.8 0.78 YMR025W 1.2 0.9 1.2 1.8 1.1 2.4 1.0 1.5 0.42 YMR135C 1.1 1.0 1.3 1.0 1.4 2.3 1.5 1.3 1.06 YMR210W 0.8 0.9 1.0 1.0 1.0 2.2 0.8 1.5 0.56 YNR040W 1.2 0.6 0.8 1.5 0.7 2.1 1.1 1.0 0.30 YPL039W 0.9 0.9 1.1 1.1 0.6 2.4 1.1 1.1 0.52 YPL099C 0.8 0.9 1.1 1.3 0.5 2.1 1.0 1.7 0.92 YPL107W 1.1 0.7 0.8 1.7 0.7 1.8 1.0 1.1 0.59 YPL138C 0.5 0.9 0.6 1.3 2.7 2.6 0.8 1.1 0.38 -
TABLE 2 Mitochondria-located protein genes yeast The level of expressed mRNA in the presence of chemical substance/ genes (1) (2) (3) (4) (5) (6) (7) (8) (9) (10) YJR048W 1.3 0.9 2.2 1.4 0.8 0.5 0.3 0.9 0.5 1.5 YOR226C 1.3 2.2 1.7 1.1 1.3 1.2 1.2 1.2 1.3 5.9 YDL174C 0.9 1.8 0.9 1.3 0.5 1.7 3.6 0.8 0.5 1.7 YBL022C 0.4 0.8 1.2 0.7 1.2 1.2 1.0 0.4 2.8 1.2 YCL057W 0.6 1.5 2.3 0.5 1.1 1.8 1.4 1.8 4.2 2.1 YDR258C 1.6 2.3 2.8 1.4 1.3 2.4 3.9 1.9 4.9 13.3 YGR028W 1.4 3.5 1.0 1.8 0.9 1.5 2.1 1.4 1.7 2.0 YGR244C 1.0 1.2 1.6 1.6 0.8 2.6 3.9 1.8 1.4 1.1 YKL142W 1.8 2.7 3.1 1.4 0.7 3.4 6.9 2.3 5.8 5.9 YNL055C 1.1 1.8 5.5 2.0 0.9 2.6 1.2 0.7 1.1 1.0 YNL071W 0.9 0.9 1.7 1.5 0.6 1.3 1.4 0.9 1.1 1.2 YOR020C 1.4 2.1 1.7 1.7 1.5 2.3 1.7 1.7 5.8 2.6 YOR037W 1.0 1.5 0.6 1.4 1.5 1.6 2.5 1.5 1.3 1.0 YDL198C 1.4 1.0 2.1 1.4 0.7 0.8 1.0 1.1 1.9 2.7 YDR231C 1.1 1.6 1.0 1.5 1.1 2.2 1.7 1.3 1.5 1.4 YER178W 0.8 0.9 3.6 1.0 0.7 2.5 1.6 0.8 1.7 1.3 YFL016C 0.8 1.0 1.6 0.9 1.3 1.3 1.4 0.7 6.4 2.9 YGR008C 2.1 3.0 1.7 3.2 0.9 2.9 3.7 1.9 3.1 2.4 YIL155C 1.0 0.7 1.4 3.7 1.3 1.4 2.2 1.0 2.5 2.9 YJL102W 1.1 0.7 0.4 0.8 1.3 1.6 0.6 0.9 3.1 2.2 YJR045C 0.5 1.9 3.9 0.5 1.2 1.0 0.8 3.2 3.0 YLR259C 0.7 1.0 3.1 1.6 1.1 0.9 1.8 0.8 1.8 2.6 YLR348C 1.1 4.5 1.2 1.2 0.9 1.9 0.9 0.9 2.1 1.3 YML054C 1.5 1.8 1.3 3.4 1.3 1.8 1.2 1.5 4.1 1.8 YMR089C 0.8 1.1 0.9 0.9 0.8 1.2 1.2 1.3 5.6 2.5 YMR152W 0.9 1.1 1.8 0.9 0.8 7.5 0.8 0.8 2.7 1.3 YNL104C 1.1 1.3 3.0 0.9 0.8 0.8 0.6 0.9 1.1 2.0 YOR130C 0.8 1.7 1.4 1.0 1.8 1.6 1.3 0.8 2.0 1.7 YPR024W 0.7 1.0 1.3 1.0 1.3 1.0 1.4 0.7 3.0 1.7 YPR067W 1.6 1.2 1.7 0.9 1.3 1.3 1.5 1.4 3.5 3.4 YBR029C 0.7 0.2 1.8 1.0 1.4 0.8 0.4 0.7 2.0 1.1 YCL009C 0.6 0.9 2.0 0.5 0.7 1.8 1.3 1.1 0.9 1.6 YER026C 0.8 0.6 3.3 1.0 1.2 2.5 1.6 0.8 0.9 1.5 YLR109W 0.8 2.9 6.0 0.9 1.3 2.1 2.6 0.9 2.4 2.7 YMR189W 0.7 0.8 1.9 2.8 0.4 1.9 0.8 0.4 0.7 0.9 YNL169C 0.7 1.4 1.4 1.2 0.7 1.4 0.7 0.8 1.1 1.1 YER069W 1.3 0.8 3.3 1.4 1.5 1.3 1.0 1.5 0.8 10.4 YIL022W 0.8 0.7 1.1 1.6 0.8 1.2 0.7 0.8 1.1 1.3 YBR146W 0.9 0.8 0.7 1.5 1.3 2.6 1.5 1.0 0.9 1.1 YDR019C 1.4 0.5 1.7 4.0 0.9 4.8 1.4 0.7 0.4 0.7 YGR207C 1.5 1.1 1.0 1.1 1.5 2.8 1.7 1.9 2.1 2.6 YMR072W 1.1 1.0 1.4 1.0 1.7 2.4 1.4 1.0 3.0 1.2 YNL037C 1.4 1.8 1.7 1.1 1.7 2.8 2.8 1.0 0.6 3.2 YOR136W 1.0 0.9 3.5 1.0 1.5 3.9 3.2 1.1 0.3 3.4 YPL271W 1.2 3.2 4.1 1.2 1.4 3.3 1.2 0.9 0.6 1.2 YAL044C 1.5 1.1 1.0 3.0 0.8 2.2 1.0 0.8 0.4 0.6 YAL054C 1.2 1.1 1.4 1.6 1.1 2.2 1.1 1.1 8.9 4.1 YBR024W 1.0 1.0 1.1 2.4 1.0 2.2 1.9 1.4 1.3 1.4 YDR405W 0.9 1.1 4.7 1.0 1.1 2.4 1.2 0.9 0.6 1.0 YGL068W 1.0 0.6 1.1 1.4 0.9 2.6 1.5 0.9 0.7 0.8 YGR220C 1.1 0.6 0.9 1.1 1.3 2.1 1.4 1.5 0.8 1.5 YHR037W 0.7 0.9 1.3 1.6 0.9 1.8 1.2 1.0 0.9 2.2 YIL070C 1.2 1.0 0.8 1.4 1.3 2.3 1.6 1.1 0.3 0.6 YIL111W 1.6 1.0 1.8 2.7 2.6 3.2 1.2 1.6 1.1 YKL138C 1.2 0.9 0.6 0.9 1.3 2.3 1.9 1.7 1.1 2.1 YKL150W 1.1 2.0 3.0 1.4 1.4 2.3 2.4 1.3 1.1 1.3 YKR006C 1.0 0.7 1.2 1.2 1.4 2.4 1.6 1.2 1.0 1.5 YLR142W 4.4 2.7 1.1 6.1 1.3 3.1 1.2 2.1 3.1 4.4 YML110C 1.1 0.8 1.9 1.6 0.8 2.6 2.0 1.4 2.7 2.2 YNL284C 1.1 0.7 0.3 1.4 1.8 1.0 2.8 1.6 0.9 1.9 YDR268W 0.8 1.5 0.4 1.2 2.2 1.0 2.4 1.0 1.0 2.0 YMR193W 1.4 1.2 0.5 1.9 2.2 1.7 2.7 1.7 0.8 1.1 YOR374W 1.3 4.5 7.3 3.9 0.9 1.4 1.9 0.9 2.3 5.9 YER061C 0.9 0.9 1.2 2.5 0.8 0.4 0.9 0.7 0.3 0.7 YIL136W 1.1 1.0 1.2 2.5 1.0 1.0 1.8 1.1 3.4 1.7 YLL009C 1.0 1.2 0.6 1.9 1.5 1.2 1.7 1.0 1.3 1.7 YLR163C 1.0 0.9 0.7 1.4 1.6 1.3 1.7 1.4 2.6 2.9 YBR291C 2.0 0.9 1.0 1.5 0.9 1.1 0.9 2.2 0.9 1.0 YIL094C 1.5 0.4 0.8 0.7 1.4 1.2 1.3 3.6 0.3 0.4 YAL015C 1.2 1.1 1.7 1.9 1.1 0.7 1.2 1.1 4.0 2.7 YJR095W 1.2 20.5 1.9 6.7 1.2 1.5 2.0 0.9 0.5 6.3 YKL085W 1.4 2.3 1.6 1.2 1.2 1.9 1.5 1.2 1.9 3.0 YMR177W 1.4 0.8 1.1 1.0 1.6 0.8 1.0 1.2 2.4 3.8 YPL224C 1.0 2.2 1.3 2.5 0.6 1.3 2.2 1.3 3.2 4.2 YER014W 1.0 0.9 0.9 0.6 0.8 4.0 1.2 3.5 1.1 YFR049W 1.5 1.5 1.8 1.2 1.3 1.3 2.6 1.5 YGR112W 1.0 2.9 1.1 1.3 0.9 1.1 1.3 1.3 2.6 1.3 YLL001W 0.9 0.7 1.2 1.2 0.6 1.0 0.8 1.0 3.5 2.4 YML042W 0.9 1.4 1.5 2.2 1.0 0.9 0.8 1.6 3.8 2.4 YNL213C 1.7 11.6 0.9 1.5 1.3 1.2 1.4 1.8 3.0 1.5 YOR386W 1.0 0.8 1.3 1.5 1.2 3.3 1.8 1.0 4.1 3.0 YBR037C 0.8 0.8 1.3 2.4 0.7 1.2 1.2 1.0 3.0 1.9 YCR024C 1.1 1.0 1.5 0.8 0.8 2.9 1.0 1.2 2.5 1.7 YDR194C 0.7 0.9 0.5 1.0 1.0 1.0 1.3 1.4 2.8 2.2 YER017C 0.8 1.1 1.4 1.3 1.0 0.5 1.1 0.5 2.7 1.8 YGL125W 1.0 3.2 4.3 0.7 0.9 1.7 0.8 2.1 2.1 YGR029W 1.1 1.4 1.0 1.0 0.8 0.6 1.6 1.7 2.7 1.1 YHL038C 1.0 1.2 1.4 0.8 1.3 0.8 1.2 1.1 4.0 1.7 YKL192C 1.1 1.0 3.7 1.1 1.1 1.8 1.1 0.9 3.5 1.6 YKR052C 0.9 1.1 2.6 2.6 1.0 0.5 1.9 1.1 1.9 3.6 YML078W 1.2 1.9 2.5 1.5 0.7 1.4 1.3 1.4 2.6 2.2 YMR056C 1.1 1.3 1.7 1.0 1.1 0.9 1.4 1.2 1.8 1.1 YNL005C 1.1 1.0 0.6 1.2 1.2 1.7 1.3 1.5 2.0 2.0 YPR047W 1.0 1.0 0.9 1.5 0.9 1.0 1.8 1.2 2.1 1.9 YPR134W 1.1 1.1 0.8 1.7 1.5 0.6 1.5 1.4 1.8 2.3 YGL191W 1.7 1.6 1.4 1.8 0.9 1.6 1.0 1.6 1.1 1.3 YLR038C 2.3 1.1 0.6 2.1 1.8 1.2 1.0 1.4 0.4 0.9 YHR008C 1.3 5.4 4.8 1.8 0.6 1.0 0.7 0.9 1.7 2.4 YPR037C 1.2 2.3 1.6 1.3 0.8 0.9 1.2 1.1 1.5 1.3 YAL039C 1.1 2.2 1.7 1.0 1.1 0.8 1.0 1.2 1.6 2.2 YDL181W 1.3 1.8 1.9 1.8 1.7 1.2 1.1 0.6 0.7 0.8 YPL215W 1.1 1.9 1.0 1.5 0.8 0.7 0.7 1.1 1.7 1.2 YPL262W 1.0 1.7 3.8 1.2 0.6 1.6 1.3 1.0 1.4 5.8 YNL256W 0.7 1.6 0.6 0.6 1.0 0.5 0.6 0.9 0.8 0.6 YBL030C 1.0 0.9 4.5 0.9 0.7 1.1 0.9 0.8 0.4 0.9 YBR221C 0.8 0.7 3.2 1.5 1.3 1.7 1.5 0.8 1.0 1.3 YKL141W 1.6 1.1 4.7 1.7 1.5 1.2 0.5 0.8 0.8 0.5 YKR066C 0.9 1.4 5.5 0.7 1.0 0.9 0.5 0.7 0.7 2.4 YMR083W 1.4 1.7 2.6 1.1 1.5 1.8 1.7 1.1 0.4 1.1 YMR203W 0.8 0.7 3.0 1.4 0.6 1.1 0.8 0.7 0.7 1.2 YBL099W 0.8 0.9 3.1 1.4 1.0 0.9 0.9 0.8 0.9 0.7 YDR178W 2.0 2.0 3.4 2.2 0.9 2.1 0.6 0.9 0.9 0.8 YDR298C 1.3 1.2 2.6 1.3 1.3 1.2 1.0 1.2 1.0 1.6 YEL024W 1.3 0.9 3.8 1.1 1.3 1.1 0.7 1.0 0.7 0.6 YGR082W 1.0 0.9 2.2 1.0 0.9 1.1 0.9 0.8 0.6 0.9 YJL133W 1.0 1.0 2.0 0.9 0.9 0.5 0.5 0.9 0.6 1.4 YJR077C 1.1 1.1 2.0 1.6 0.9 0.9 0.7 0.8 0.4 0.7 YJR121W 0.9 1.1 3.3 1.0 0.8 1.5 1.0 0.7 0.8 1.3 YKL148C 0.9 0.8 3.7 0.7 0.8 0.5 0.6 0.8 1.7 1.7 YLL041C 1.1 0.5 4.6 1.0 1.6 1.2 0.3 0.8 0.7 0.8 YLR304C 0.7 0.6 5.0 0.7 0.6 1.9 0.6 0.6 0.1 2.2 YOR142W 1.0 1.2 3.4 1.0 1.4 1.6 1.0 0.8 1.1 1.5 YOR176W 0.7 2.6 2.7 0.9 1.0 0.9 0.5 1.0 1.0 0.5 YPL135W 0.9 1.2 2.5 1.2 1.6 1.3 1.2 1.0 0.5 2.8 YDR529C 1.8 1.0 0.9 3.2 1.2 0.8 0.5 1.3 0.5 0.6 YGL018C 1.1 1.0 1.8 3.0 1.1 0.4 1.1 0.8 0.5 1.4 YBR003W 0.9 0.8 1.0 1.9 0.7 1.2 1.1 0.9 1.0 1.3 YBR044C 0.8 1.4 0.7 1.9 1.4 1.0 1.5 1.1 0.8 1.2 YBR091C 1.1 1.0 0.6 3.0 1.1 0.7 1.0 1.5 0.7 1.6 YBR185C 1.2 1.0 1.3 2.0 0.8 1.2 1.2 1.1 0.9 1.6 YBR282W 1.0 1.0 0.5 2.3 1.0 1.4 1.2 1.4 1.0 0.9 YDR347W 1.1 0.8 0.9 3.5 0.8 1.2 1.2 1.2 0.8 1.6 YEL039C 1.1 0.7 1.3 5.1 0.9 1.5 0.6 1.1 1.2 1.2 YGR076C 1.3 1.6 0.6 2.3 0.9 1.2 1.7 1.9 1.2 1.8 YGR174C 1.1 1.6 0.6 2.4 1.0 1.4 1.0 1.6 1.8 0.7 YKL003C 1.1 0.7 0.8 1.8 1.0 1.0 1.4 1.2 1.5 2.2 YKL016C 1.5 1.3 0.7 1.7 1.5 0.8 1.5 1.6 1.3 1.8 YKL170W 1.0 0.8 0.5 1.9 1.3 1.5 1.5 1.2 0.9 1.1 YKL194C 0.9 0.7 0.8 1.6 1.8 1.4 2.1 1.1 1.3 1.4 YLR395C 1.8 1.3 2.2 1.9 0.7 0.4 1.0 1.0 0.9 YML120C 1.1 1.2 1.9 1.9 0.6 0.6 0.8 0.9 1.3 1.5 YOR100C 1.3 1.4 1.6 1.7 1.0 1.2 1.6 1.0 2.0 2.6 YOR150W 1.7 1.2 1.0 1.9 0.8 0.9 1.2 1.1 0.8 1.8 YOR187W 1.0 0.5 1.9 2.0 0.6 1.7 1.5 0.7 0.6 0.8 YJL166W 2.1 1.5 1.6 1.3 1.6 0.7 0.8 1.4 1.3 1.2 YMR035W 1.2 1.7 1.5 1.7 0.8 1.5 2.3 1.4 1.7 1.6 YBL038W 1.0 0.9 0.5 1.8 0.9 0.7 8.0 1.6 1.4 1.5 YDR377W 1.3 1.1 1.3 1.4 1.9 1.3 1.1 1.3 1.0 0.9 YGL187C 1.5 0.8 1.6 1.8 1.3 1.1 0.6 0.7 0.6 0.6 YCR046C 1.0 1.2 1.2 1.6 1.0 0.8 1.2 0.9 1.9 1.4 YML129C 1.1 0.9 0.9 1.2 1.7 1.7 1.8 1.2 1.4 2.2 YOL096C 1.1 1.0 1.2 1.6 1.2 1.3 1.7 1.0 1.3 1.4 YBR122C 0.9 0.9 0.3 1.1 1.5 1.1 2.0 1.3 1.1 1.4 YBR251W 1.0 0.9 1.0 1.2 1.3 2.0 1.4 1.3 0.5 1.1 YCR083W 1.1 2.8 1.5 1.8 1.6 2.4 1.8 1.5 1.8 1.8 YDL067C 1.8 1.0 1.6 1.3 2.0 0.9 0.8 1.1 0.9 0.9 YDR079W 1.3 1.1 0.8 1.1 1.2 1.7 1.3 2.6 0.9 0.8 YGR062C 0.9 1.0 0.7 1.4 0.7 0.9 1.3 0.8 1.0 1.4 YJL096W 1.0 1.0 0.8 1.3 1.9 1.0 1.7 1.3 1.0 1.4 YJL180C 0.9 1.6 1.1 1.3 1.5 1.3 1.6 1.0 1.4 1.4 YLR295C 1.4 1.1 1.1 1.7 2.2 1.1 1.1 1.2 1.4 1.2 YMR023C 1.4 1.3 0.5 1.9 1.7 1.1 1.9 1.4 1.5 2.6 YMR267W 0.8 1.8 0.7 0.9 1.0 1.4 1.2 1.5 0.4 0.8 YNL073W 0.8 1.4 0.9 1.7 0.6 0.5 1.1 1.0 0.9 1.8 YOR316C 0.7 2.5 1.5 1.5 1.0 0.9 1.4 0.8 1.6 2.0 YPL040C 1.1 1.0 0.8 1.7 0.8 1.1 0.8 1.1 0.2 1.2 YPL134C 1.5 1.0 1.6 1.6 1.4 1.2 1.2 1.3 0.6 0.8 yeast The level of expressed mRNA in the absence of chemical substance genes (11) (12) (13) (14) (15) (16) (17) (18) Intensity YJR048W 1.0 0.8 0.4 2.5 0.6 1.5 1.2 1.2 1.19 YOR226C 1.5 0.6 0.9 2.7 1.0 0.7 1.0 0.7 0.58 YDL174C 0.9 2.8 5.9 1.1 0.6 5.1 2.2 4.0 0.63 YBL022C 1.1 0.9 2.6 1.0 1.5 1.0 0.9 0.7 0.76 YCL057W 1.6 1.0 3.8 1.0 2.8 1.5 0.9 1.1 0.76 YDR258C 1.7 1.8 5.2 1.5 0.6 1.0 1.3 1.3 0.87 YGR028W 1.1 1.5 2.6 1.2 1.0 2.2 1.5 2.6 0.91 YGR244C 1.8 1.9 2.6 1.2 2.0 2.6 1.9 3.1 1.12 YKL142W 2.0 1.9 3.3 2.3 1.3 3.3 2.4 3.6 1.68 YNL055C 1.9 1.7 2.4 0.9 1.1 2.6 1.2 1.7 4.10 YNL071W 1.6 1.3 2.5 0.8 1.1 1.1 1.0 1.2 1.61 YOR020C 2.5 0.8 3.0 1.6 1.5 1.4 1.4 1.7 1.66 YOR037W 1.2 1.2 2.1 1.0 0.9 1.4 1.2 1.6 0.61 YDL198C 2.5 1.2 2.0 1.7 1.2 1.4 1.5 1.1 1.19 YDR231C 1.3 1.1 2.4 1.5 1.0 3.0 1.2 1.3 0.92 YER178W 2.5 1.3 2.4 0.9 1.8 1.0 1.1 0.9 2.18 YFL016C 1.2 1.0 2.8 0.8 0.8 0.6 1.2 0.9 1.25 YGR008C 2.6 2.0 3.4 1.3 1.5 2.3 1.7 4.2 3.03 YIL155C 1.3 1.4 2.0 1.3 1.4 3.8 1.1 1.4 0.51 YJL102W 0.7 0.8 2.6 1.5 1.5 0.6 1.0 1.1 0.22 YJR045C 1.4 1.0 2.3 0.5 2.3 0.8 0.7 0.9 3.78 YLR259C 3.0 0.7 2.5 0.8 2.1 1.3 0.8 1.0 2.09 YLR348C 1.3 0.9 1.9 1.0 2.4 1.1 1.1 1.0 0.64 YML054C 1.4 1.8 2.8 2.1 1.1 7.8 1.1 1.6 0.25 YMR089C 1.3 0.8 2.3 0.9 1.8 1.1 0.9 1.1 0.69 YMR152W 1.2 1.3 1.9 1.1 0.6 1.0 1.5 0.9 0.71 YNL104C 2.1 1.1 2.1 0.9 2.5 1.5 0.9 0.9 1.69 YOR130C 0.6 0.9 2.1 1.3 1.0 0.8 1.5 1.1 0.51 YPR024W 0.9 0.8 2.5 0.7 1.0 1.6 1.1 0.8 0.84 YPR067W 1.8 1.0 3.0 1.6 1.3 0.8 1.0 1.0 0.66 YBR029C 0.7 1.3 1.7 0.9 3.5 0.9 0.6 0.8 1.56 YCL009C 1.5 1.7 1.6 0.7 6.5 0.9 1.1 0.8 0.68 YER026C 0.9 1.7 1.9 1.1 4.0 1.4 1.7 3.2 4.48 YLR109W 1.5 1.6 3.2 2.3 3.9 1.8 1.1 1.2 3.86 YMR189W 8.2 0.6 0.9 1.6 5.6 0.9 1.0 0.8 0.88 YNL169C 0.8 1.0 1.7 0.9 3.4 0.8 1.1 1.3 1.05 YER069W 1.5 0.8 1.4 1.3 2.4 1.1 1.1 0.9 0.25 YIL022W 1.0 0.9 1.2 0.6 2.9 1.1 0.8 0.7 0.52 YBR146W 1.2 1.0 1.7 1.2 1.0 2.9 1.0 1.2 1.61 YDR019C 1.8 0.7 1.0 1.6 1.8 1.8 1.2 1.6 2.48 YGR207C 1.4 1.1 1.0 2.2 0.6 1.8 1.2 1.8 1.49 YMR072W 1.9 0.8 2.1 1.2 0.8 1.7 0.9 1.9 2.06 YNL037C 1.4 1.3 1.9 1.3 0.9 1.4 0.9 1.3 2.05 YOR136W 1.4 1.2 1.5 0.9 1.2 1.3 0.8 1.3 3.20 YPL271W 1.7 0.8 1.2 1.3 0.8 1.4 1.2 1.3 1.34 YAL044C 1.4 0.6 1.1 1.4 0.7 1.0 1.4 1.8 4.07 YAL054C 1.3 1.0 1.8 1.3 0.9 2.5 1.5 1.4 0.24 YBR024W 1.3 1.1 1.7 1.9 0.8 2.3 1.0 1.2 1.14 YDR405W 1.0 1.2 1.3 1.1 2.5 1.3 1.3 0.9 0.44 YGL068W 1.0 1.1 1.0 0.9 0.6 1.8 1.8 1.0 3.35 YGR220C 1.1 0.9 1.1 1.5 1.1 2.3 0.9 1.1 1.42 YHR037W 1.7 1.1 1.1 1.1 1.1 2.0 1.0 1.4 1.15 YIL070C 1.0 0.8 0.7 1.3 1.0 2.4 0.7 1.1 1.69 YIL111W 2.1 0.9 1.7 1.5 1.1 2.5 1.9 3.9 1.52 YKL138C 1.2 0.8 0.8 1.6 0.6 2.5 1.0 1.3 1.29 YKL150W 1.9 1.2 1.8 1.4 0.9 6.1 1.2 2.7 2.20 YKR006C 1.2 0.8 0.9 1.6 0.9 2.3 0.8 1.1 1.39 YLR142W 3.8 0.8 1.2 2.1 1.6 3.4 1.9 3.2 0.28 YML110C 1.7 1.1 1.8 1.4 1.3 2.3 1.1 1.6 2.01 YNL284C 1.3 0.7 1.0 1.5 0.8 2.4 1.0 1.5 1.26 YDR268W 1.1 0.7 1.0 1.4 1.0 1.6 1.1 1.2 0.47 YMR193W 1.6 0.6 0.9 1.5 0.8 3.7 1.1 1.7 0.93 YOR374W 2.6 1.5 1.7 1.1 2.5 2.5 1.2 2.4 1.24 YER061C 2.2 0.7 0.9 1.0 0.8 1.8 1.2 1.2 0.84 YIL136W 4.8 0.9 1.7 1.7 1.5 4.5 1.3 3.2 0.95 YLL009C 3.5 0.7 0.9 1.4 1.1 2.8 0.9 1.2 1.66 YLR163C 2.2 0.7 1.4 1.3 1.2 1.4 0.9 1.1 0.55 YBR291C 1.1 0.9 1.0 1.7 0.5 1.5 0.9 1.3 1.19 YIL094C 1.8 1.0 0.7 1.0 0.5 0.9 0.9 1.0 2.26 YAL015C 1.4 1.0 1.2 1.6 0.7 2.0 1.1 1.2 0.61 YJR095W 0.6 0.7 0.8 1.3 0.8 0.8 1.3 0.9 0.23 YKL085W 1.8 0.8 1.5 1.0 0.5 1.7 0.9 1.3 2.16 YMR177W 1.4 0.6 0.5 1.2 0.8 0.5 0.9 0.9 0.55 YPL224C 0.8 1.1 1.3 1.4 1.0 2.5 1.3 1.9 0.64 YER014W 0.9 1.1 1.5 1.2 2.3 0.8 1.0 0.9 0.43 YFR049W 1.7 1.2 1.4 1.2 0.7 0.9 1.3 1.0 0.83 YGR112W 1.3 0.7 1.1 1.1 1.2 2.8 0.9 1.2 0.31 YLL001W 0.9 0.7 1.7 1.2 0.9 1.3 0.9 1.3 0.70 YML042W 2.5 1.0 1.2 1.4 1.7 4.8 1.0 0.9 0.29 YNL213C 1.5 0.8 0.9 1.8 1.0 1.7 0.9 1.2 0.70 YOR386W 1.4 1.2 2.4 0.9 1.3 1.2 2.1 1.7 0.46 YBR037C 1.5 0.7 1.2 1.2 1.0 2.7 1.6 1.3 0.60 YCR024C 1.4 0.8 0.9 1.3 1.0 1.2 0.9 1.0 0.32 YDR194C 1.2 0.6 1.2 0.8 1.1 0.8 0.6 0.8 2.19 YER017C 0.9 1.0 1.5 1.1 2.1 1.0 0.9 1.0 0.43 YGL125W 1.6 1.0 1.4 1.0 1.9 1.2 1.2 1.1 0.27 YGR029W 1.2 0.6 1.0 2.0 0.4 1.1 1.1 1.3 0.71 YHL038C 0.8 1.6 1.3 0.6 0.8 0.5 0.9 0.6 1.95 YKL192C 1.1 1.2 1.7 1.5 1.2 2.1 1.0 0.8 1.57 YKR052C 1.3 0.9 1.2 1.1 0.5 2.5 0.8 1.5 1.15 YML078W 2.4 1.2 1.7 1.7 1.0 1.8 1.3 1.6 1.98 YMR056C 1.6 0.9 0.9 1.1 0.7 2.4 1.0 1.1 0.72 YNL005C 1.2 0.9 1.5 1.3 1.0 1.6 0.9 1.5 1.52 YPR047W 1.1 0.9 1.3 1.0 0.8 2.8 1.0 1.5 0.39 YPR134W 1.3 0.9 1.1 1.5 0.7 2.4 1.0 1.2 0.65 YGL191W 1.6 0.9 1.1 1.6 0.7 1.8 1.2 1.7 2.35 YLR038C 1.4 0.6 0.5 1.6 0.7 2.1 1.2 2.1 1.52 YHR008C 2.1 0.7 1.2 1.6 1.7 2.2 0.9 1.0 1.04 YPR037C 0.9 0.9 1.0 1.6 4.1 1.8 1.2 1.7 0.80 YAL039C 1.1 1.4 1.6 1.2 3.3 2.2 1.4 1.1 0.39 YDL181W 0.8 0.9 0.9 1.1 0.4 1.1 1.5 1.4 0.85 YPL215W 1.1 0.7 0.7 1.2 0.6 1.4 1.0 1.1 1.10 YPL262W 1.4 1.1 1.5 1.2 0.6 1.4 1.1 1.2 0.79 YNL256W 0.6 0.6 1.3 0.7 0.9 0.4 0.6 0.6 1.09 YBL030C 1.1 0.9 0.5 0.8 1.8 1.0 1.0 1.1 3.12 YBR221C 1.2 1.3 1.7 0.8 1.1 1.5 0.9 1.0 3.62 YKL141W 1.2 0.8 0.8 1.4 0.6 2.8 0.9 1.8 2.84 YKR066C 1.3 0.9 0.6 1.5 0.6 1.3 0.9 1.1 1.25 YMR083W 1.6 0.7 0.9 0.8 1.3 1.3 0.9 1.1 2.52 YMR203W 2.3 0.7 1.1 0.7 1.2 0.9 0.8 0.7 1.62 YBL099W 2.1 1.0 0.9 0.6 1.0 0.9 0.7 1.2 3.49 YDR178W 2.0 1.3 1.5 1.5 0.7 3.0 1.2 2.3 2.27 YDR298C 1.2 1.1 1.2 1.5 0.8 2.0 1.1 1.6 2.69 YEL024W 0.9 0.8 0.6 1.1 0.6 2.1 1.1 1.5 1.59 YGR082W 1.3 0.8 0.5 0.9 1.2 1.3 0.9 0.8 1.47 YJL133W 1.2 0.8 0.8 0.7 0.9 0.6 0.8 0.7 0.91 YJR077C 1.6 1.0 0.9 0.7 1.5 0.7 1.0 0.8 1.79 YJR121W 0.9 0.8 1.0 0.7 0.9 1.2 1.1 1.4 3.99 YKL148C 1.5 0.8 0.8 0.8 0.6 1.1 0.8 1.0 0.54 YLL041C 1.3 0.8 1.0 1.2 0.4 3.1 1.1 1.7 1.75 YLR304C 1.6 1.0 0.5 0.7 1.6 1.8 0.5 0.7 2.39 YOR142W 1.5 0.8 1.4 0.8 1.1 0.8 0.9 1.0 1.31 YOR176W 1.4 1.3 1.5 0.8 0.8 1.4 1.2 2.1 1.23 YPL135W 1.3 1.1 1.2 1.1 1.5 1.2 1.5 1.7 1.50 YDR529C 0.8 0.6 0.7 1.5 0.5 1.8 1.0 2.3 3.11 YGL018C 1.1 1.0 1.3 1.2 1.1 1.5 0.8 1.0 0.36 YBR003W 1.3 0.8 1.2 0.8 0.7 2.0 1.1 1.3 1.06 YBR044C 1.1 0.8 1.2 0.9 0.9 1.4 0.9 1.3 0.57 YBR091C 0.7 0.8 1.2 1.7 0.9 0.9 1.0 1.0 0.87 YBR185C 1.2 0.7 1.0 1.7 1.0 1.7 0.8 1.3 0.89 YBR282W 0.9 0.8 1.3 1.4 1.1 1.5 0.9 1.2 1.36 YDR347W 0.8 0.8 1.3 1.5 1.0 1.7 0.9 1.2 1.33 YEL039C 1.7 0.6 0.5 1.4 0.4 3.5 0.7 1.1 1.59 YGR076C 1.7 1.0 1.4 2.3 0.5 2.3 0.9 1.5 0.97 YGR174C 1.3 0.9 1.5 1.6 0.7 3.2 1.3 2.3 1.05 YKL003C 1.7 0.7 1.3 2.0 1.0 2.3 1.0 1.2 0.90 YKL016C 1.3 1.0 1.3 1.6 0.7 1.8 1.0 1.7 2.08 YKL170W 0.7 0.8 0.9 1.3 0.8 2.1 1.1 1.4 1.27 YKL194C 1.6 0.6 1.1 1.4 0.8 1.2 1.1 1.1 0.52 YLR395C 1.5 0.6 0.5 1.7 0.4 1.2 1.2 2.3 1.76 YML120C 1.3 0.9 1.2 0.8 0.5 1.5 1.0 1.6 0.74 YOR100C 1.4 0.8 1.0 1.4 4.3 2.8 0.9 0.8 0.32 YOR150W 1.0 0.8 1.0 1.6 0.8 1.6 0.9 1.3 1.11 YOR187W 1.4 0.8 0.7 0.6 1.3 1.6 0.8 1.3 3.12 YJL166W 1.4 0.7 0.8 1.9 0.5 2.3 1.7 4.0 2.31 YMR035W 1.5 0.5 1.4 1.3 1.1 1.5 2.2 2.4 0.96 YBL038W 0.7 0.7 1.0 2.3 0.7 1.8 1.2 1.9 1.56 YDR377W 1.4 0.9 0.7 1.4 0.6 1.8 1.2 2.5 3.00 YGL187C 0.7 0.8 0.7 0.9 0.3 1.4 0.9 2.4 2.73 YCR046C 1.5 1.1 1.5 1.3 1.4 2.8 1.3 1.0 0.63 YML129C 1.2 0.8 1.0 1.4 1.1 2.9 1.3 1.3 1.04 YOL096C 1.2 1.2 1.4 1.4 1.0 2.3 1.2 1.2 0.64 YBR122C 1.2 0.7 0.8 1.2 0.7 1.9 0.9 1.5 1.53 YBR251W 1.5 1.1 1.0 1.6 0.8 3.0 0.9 1.4 1.13 YCR083W 1.8 1.1 1.8 2.4 1.0 3.1 1.3 1.3 0.98 YDL067C 1.4 1.0 0.6 1.4 0.7 1.8 1.2 1.7 1.85 YDR079W 1.3 1.1 1.3 1.5 0.6 2.6 1.1 1.3 1.06 YGR062C 1.6 1.0 1.5 1.2 0.5 1.8 0.9 1.1 0.54 YJL096W 1.2 1.0 0.7 2.1 1.0 2.2 1.1 1.2 1.21 YJL180C 1.4 0.8 1.2 1.4 0.6 2.0 0.9 1.4 1.08 YLR295C 1.3 0.5 0.8 1.2 0.5 2.4 0.9 1.5 1.07 YMR023C 0.8 0.7 1.1 1.6 0.7 2.1 1.1 1.4 0.48 YMR267W 1.0 0.8 0.7 1.0 0.9 2.6 0.9 1.3 0.94 YNL073W 1.1 0.7 1.2 0.7 0.7 1.8 0.8 1.0 0.52 YOR316C 2.4 1.1 1.6 1.0 1.5 2.2 0.8 1.0 0.93 YPL040C 0.9 0.9 1.0 1.1 1.1 2.7 0.8 1.1 0.33 YPL134C 1.7 0.8 1.0 1.4 1.1 3.3 1.3 1.3 0.70 -
TABLE 3 DNA repair protein genes yeast The level of expressed mRNA in the presence of chemical substance/ genes (1) (2) (3) (4) (5) (6) (7) (8) (9) (10) YFL014W 3.4 5.1 5.7 11.0 1.0 9.3 5.5 3.4 13.1 5.8 YGL163C 0.9 0.8 0.6 4.3 1.5 0.9 1.0 1.4 5.8 2.3 YKL145W 0.8 1.4 1.2 1.0 1.4 2.1 1.6 1.5 3.5 2.7 YIL153W 0.8 1.4 1.3 2.9 1.0 0.9 1.6 0.5 4.3 1.1 YIR002C 0.8 1.1 0.5 0.6 1.2 2.2 1.3 1.2 1.7 1.4 YAL015C 1.2 1.1 1.7 1.9 1.1 0.7 1.2 1.1 4.0 2.7 YBR073W 0.7 1.0 0.9 0.7 1.2 0.7 0.6 1.1 2.5 1.8 YDL200C 1.4 2.0 1.2 1.8 1.1 0.6 1.7 1.5 2.4 1.8 YGL058W 1.1 1.1 0.6 0.7 1.0 1.0 0.0 1.3 3.7 1.8 YIL143C 0.9 0.8 1.1 0.9 0.8 1.4 0.8 0.9 7.1 3.5 YML032C 0.8 0.9 1.1 0.7 1.0 0.9 0.8 0.9 3.0 1.1 YNL250W 0.9 2.2 0.8 1.2 0.8 0.8 1.2 1.3 4.2 2.3 YOR386W 1.0 0.8 1.3 1.5 1.2 3.3 1.8 1.0 4.1 3.0 YBL019W 0.9 9.1 0.7 1.2 1.0 1.0 1.2 1.2 2.6 1.4 YDR369C 1.1 1.1 2.4 1.1 1.0 0.6 0.4 1.0 2.4 1.8 YEL037C 0.9 2.0 0.9 1.0 0.5 0.6 0.8 0.8 2.6 1.2 YER162C 1.0 1.2 1.0 1.1 0.9 0.7 0.5 0.9 2.8 1.6 YGR258C 0.7 0.9 0.7 0.7 1.5 2.2 1.5 0.8 2.5 1.5 YJR052W 1.1 1.0 1.1 1.0 1.0 1.4 1.2 1.7 4.5 2.3 YOR005C 1.2 1.8 1.0 0.8 1.3 1.3 1.4 1.3 2.4 1.5 YPL022W 0.7 0.8 0.7 1.2 0.8 5.2 0.8 1.0 2.1 1.6 YPL164C 1.1 0.7 1.1 1.0 1.2 1.7 0.9 1.0 2.1 2.0 YPL194W 0.9 1.4 0.4 1.1 1.3 1.1 1.5 1.3 9.6 3.1 YPR025C 1.1 0.8 0.6 0.6 1.6 0.9 1.4 1.3 1.9 1.7 YGR180C 3.1 1.1 1.9 1.0 2.0 0.6 0.5 1.0 1.4 1.5 YEL019C 1.1 1.6 0.3 0.7 0.9 1.5 1.2 0.9 0.7 0.7 YLR288C 1.2 0.8 1.6 1.8 1.7 1.2 1.3 1.5 0.8 1.3 YMR284W 1.1 1.0 0.5 2.0 0.8 0.8 0.8 1.1 1.6 1.8 YMR035W 1.2 1.7 1.5 1.7 0.8 1.5 2.3 1.4 1.7 1.6 YOL043C 1.1 0.9 0.8 1.7 1.2 0.8 1.0 0.9 1.0 1.8 YGR231C 1.0 1.2 0.7 1.0 1.3 1.9 2.1 1.1 3.2 2.3 YHR164C 0.9 1.3 0.9 0.7 0.9 1.4 0.8 1.1 1.3 3.1 YJR046W 1.0 1.2 1.2 1.5 0.8 2.0 0.9 0.9 6.0 2.4 YLR103C 0.8 1.5 1.1 0.4 1.0 1.1 1.3 1.4 0.8 0.5 YMR072W 1.1 1.0 1.4 1.0 1.7 1.6 1.4 1.0 3.0 1.2 YDR054C 1.3 1.0 0.7 1.4 0.7 1.9 1.1 1.5 2.9 3.2 YAR007C 0.7 1.9 0.8 0.5 1.5 1.6 0.8 1.1 4.1 1.7 YGL058W 1.1 1.1 0.6 0.7 1.0 1.5 0.0 1.3 3.7 1.8 YIL036W 0.9 1.3 1.3 1.8 0.9 1.8 1.4 1.1 3.6 2.7 YNL213C 1.7 11.6 0.9 1.5 1.3 1.7 1.4 1.8 3.0 1.5 YNL312W 0.9 1.0 1.6 0.7 1.4 1.7 0.5 1.2 3.7 2.5 YNL261W 1.0 1.3 0.6 1.3 0.7 1.3 1.0 1.1 2.3 1.5 YGR180C 3.1 1.1 1.9 1.0 2.0 1.0 0.5 1.0 1.4 1.5 YJL026W 2.5 2.4 2.9 1.0 1.7 1.0 0.5 1.2 1.0 1.1 YDL017W 0.8 2.3 1.2 1.3 1.2 1.1 1.1 1.2 0.8 1.8 YML058W 1.9 1.2 5.8 1.9 0.6 1.3 0.6 0.7 1.1 1.2 YLR233C 1.1 0.9 2.0 2.0 1.2 0.8 0.8 1.1 0.6 0.5 YMR284W 1.1 1.0 0.5 2.0 0.8 1.2 0.8 1.1 1.6 1.8 YGL163C 0.9 0.8 0.6 4.3 1.5 0.9 1.0 1.4 5.8 2.3 YGL127C 1.0 1.9 1.3 1.7 1.3 0.6 1.0 0.9 1.2 1.5 YMR072W 1.1 1.0 1.4 1.0 1.7 2.4 1.4 1.0 3.0 1.2 YGL249W 1.4 0.8 0.5 0.8 1.1 2.5 1.2 0.9 0.3 2.4 YBR272C 0.8 1.8 1.3 1.0 1.1 1.9 1.1 1.7 2.7 YDL059C 2.6 5.1 1.4 1.7 1.2 1.2 1.1 1.2 10.5 7.8 YAR007C 0.7 1.9 0.8 0.5 1.5 0.6 0.8 1.1 4.1 1.7 YBR073W 0.7 1.0 0.9 0.7 1.2 0.7 0.6 1.1 2.5 1.8 YML032C 0.8 0.9 1.1 0.7 1.0 0.9 0.8 0.9 3.0 1.1 YNL250W 0.9 2.2 0.8 1.2 0.8 0.8 1.2 1.3 4.2 2.3 YCR014C 0.8 1.0 0.8 0.6 1.2 1.1 1.1 1.0 2.4 1.0 YDR369C 1.1 1.1 2.4 1.1 1.0 0.6 0.4 1.0 2.4 1.8 YIL072W 0.8 3.1 1.1 2.6 1.5 1.2 1.7 1.4 2.9 2.1 YOR005C 1.2 1.8 1.0 0.8 1.3 1.3 1.4 1.3 2.4 1.5 YPL164C 1.1 0.7 1.1 1.0 1.2 1.7 0.9 1.0 2.1 2.0 YPL194W 0.9 1.4 0.4 1.1 1.3 1.1 1.5 1.3 9.6 3.1 YGR180C 3.1 1.1 1.9 1.0 2.0 0.6 0.5 1.0 1.4 1.5 YEL019C 1.1 1.6 0.3 0.7 0.9 1.5 1.2 0.9 0.7 0.7 YML058W 1.9 1.2 5.8 1.9 0.6 0.6 0.6 0.7 1.1 1.2 YLR288C 1.2 0.8 1.6 1.8 1.7 1.2 1.3 1.5 0.8 1.3 YMR284W 1.1 1.0 0.5 2.0 0.8 0.8 0.8 1.1 1.6 1.8 YMR096W 1.7 1.7 1.1 0.8 1.0 2.2 1.9 2.0 3.3 3.7 YGL091C 2.0 1.8 1.0 1.7 0.8 1.6 1.3 1.8 10.8 6.0 yeast The level of expressed mRNA in the absence of chemical substance genes (11) (12) (13) (14) (15) (16) (17) (18) Intensity YFL014W 5.0 4.3 15.2 7.3 6.3 14.2 1.5 8.8 2.14 YGL163C 0.4 0.9 3.1 1.6 1.8 1.0 0.9 0.8 0.26 YKL145W 1.8 1.3 2.7 1.0 1.3 1.2 1.1 1.5 2.29 YIL153W 1.0 1.0 1.2 1.0 2.8 1.3 0.9 0.7 0.32 YIR002C 0.8 1.3 1.2 1.1 1.1 1.4 1.1 1.2 0.58 YAL015C 1.4 1.0 1.2 1.6 0.7 2.0 1.1 1.2 0.61 YBR073W 0.5 0.9 1.4 1.0 1.3 0.8 0.7 0.8 0.63 YDL200C 1.2 1.1 1.1 1.8 0.7 1.8 0.9 1.6 0.79 YGL058W 0.8 1.3 1.0 1.3 1.3 0.6 1.1 0.7 1.07 YIL143C 1.5 0.9 1.7 1.0 1.3 1.1 0.9 0.9 0.56 YML032C 1.0 0.9 1.8 1.0 1.7 1.2 1.0 1.0 0.66 YNL250W 1.0 1.4 1.3 1.6 1.3 1.4 1.0 1.0 0.31 YOR386W 1.4 1.2 2.4 0.9 1.3 1.2 2.1 1.7 0.46 YBL019W 1.0 0.8 0.9 1.1 0.6 1.9 0.8 1.1 0.38 YDR369C 1.1 0.9 0.1 0.7 1.2 0.6 0.8 0.7 1.88 YEL037C 1.0 1.1 2.0 1.0 1.6 0.5 1.0 0.8 0.82 YER162C 0.5 0.4 0.8 0.8 1.0 1.0 1.2 0.9 0.45 YGR258C 0.3 0.9 1.9 1.2 1.1 1.2 1.0 0.9 0.37 YJR052W 1.1 1.1 1.8 1.4 1.4 1.4 1.0 1.3 0.36 YOR005C 1.2 0.9 2.1 1.2 0.8 1.4 1.1 1.0 0.29 YPL022W 0.8 0.7 1.4 0.9 0.9 1.0 0.9 0.9 0.72 YPL164C 1.1 0.9 1.0 0.9 1.3 1.4 1.0 1.0 0.25 YPL194W 0.9 0.9 1.4 1.1 1.4 0.9 1.0 0.8 0.22 YPR025C 0.9 0.7 1.1 1.3 1.1 1.3 1.1 1.5 0.87 YGR180C 1.0 0.9 0.9 0.9 1.3 1.2 1.0 1.9 3.90 YEL019C 1.2 1.0 1.0 1.7 1.5 0.3 0.8 0.9 0.27 YLR288C 1.4 0.6 0.7 1.2 0.9 1.5 1.2 1.3 0.31 YMR284W 1.1 0.6 1.0 1.2 0.7 1.3 1.1 1.3 0.54 YMR035W 1.5 0.5 1.4 1.3 1.1 1.5 2.2 2.4 0.96 YOL043C 1.2 0.8 0.9 1.5 0.6 2.5 1.0 1.0 0.38 YGR231C 1.6 1.3 3.9 2.2 1.3 2.5 1.0 1.5 1.74 YHR164C 0.6 1.2 2.0 1.3 2.2 1.1 0.8 1.0 0.44 YJR046W 0.6 0.9 3.0 1.0 1.1 0.8 0.7 0.7 0.45 YLR103C 0.9 1.6 3.0 1.0 0.8 1.5 1.1 1.4 1.32 YMR072W 1.9 0.8 2.1 1.2 0.8 1.7 0.9 1.9 2.06 YDR054C 1.9 1.0 2.5 1.1 1.6 1.4 0.8 1.4 1.18 YAR007C 0.9 0.9 1.7 1.4 1.2 0.9 0.8 1.0 1.03 YGL058W 0.8 1.3 1.0 1.3 1.3 0.6 1.1 0.7 1.07 YIL036W 1.2 1.2 1.9 1.1 0.8 1.3 1.1 1.3 0.66 YNL213C 1.5 0.8 0.9 1.8 1.0 1.7 0.9 1.2 0.70 YNL312W 1.4 0.9 0.7 1.1 0.8 0.8 1.2 1.1 2.05 YNL261W 0.8 0.8 0.8 1.4 0.7 1.1 0.8 1.0 0.91 YGR180C 1.0 0.9 0.9 0.9 1.3 1.2 1.0 1.9 3.90 YJL026W 1.3 1.0 1.2 1.0 1.1 1.6 1.4 2.1 3.74 YDL017W 0.8 0.8 0.9 1.3 1.3 1.0 0.8 1.0 0.38 YML058W 3.3 0.9 1.4 1.1 2.5 1.3 1.3 1.5 2.14 YLR233C 0.8 0.9 1.0 1.1 1.1 1.1 1.0 1.2 0.43 YMR284W 1.1 0.6 1.0 1.2 0.7 1.3 1.1 1.3 0.54 YGL163C 0.4 0.9 3.1 1.6 1.8 1.0 0.9 0.8 0.26 YGL127C 1.0 1.4 1.7 1.0 1.5 1.3 1.0 1.2 0.54 YMR072W 1.9 0.8 2.1 1.2 0.8 1.7 0.9 1.9 2.06 YGL249W 0.6 0.8 0.8 1.9 0.7 1.4 1.0 1.0 0.20 YBR272C 1.1 0.5 1.3 1.0 0.5 1.7 1.1 1.2 0.52 YDL059C 2.0 1.3 1.7 4.7 0.7 1.5 0.8 0.9 0.63 YAR007C 0.9 0.9 1.7 1.4 1.2 0.9 0.8 1.0 1.03 YBR073W 0.5 0.9 1.4 1.0 1.3 0.8 0.7 0.8 0.63 YML032C 1.0 0.9 1.8 1.0 1.7 1.2 1.0 1.0 0.66 YNL250W 1.0 1.4 1.3 1.6 1.3 1.4 1.0 1.0 0.31 YCR014C 0.8 0.7 1.2 1.0 0.7 1.5 1.0 0.9 0.34 YDR369C 1.1 0.9 0.1 0.7 1.2 0.6 0.8 0.7 1.88 YIL072W 1.8 1.1 1.4 2.0 1.4 1.4 1.0 1.1 0.23 YOR005C 1.2 0.9 2.1 1.2 0.8 1.4 1.1 1.0 0.29 YPL164C 1.1 0.9 1.0 0.9 1.3 1.4 1.0 1.0 0.25 YPL194W 0.9 0.9 1.4 1.1 1.4 0.9 1.0 0.8 0.22 YGR180C 1.0 0.9 0.9 0.9 1.3 1.2 1.0 1.9 3.90 YEL019C 1.2 1.0 1.0 1.7 1.5 0.3 0.8 0.9 0.27 YML058W 3.3 0.9 1.4 1.1 2.5 1.3 1.3 1.5 2.14 YLR288C 1.4 0.6 0.7 1.2 0.9 1.5 1.2 1.3 0.31 YMR284W 1.1 0.6 1.0 1.2 0.7 1.3 1.1 1.3 0.54 YMR096W 1.5 1.4 8.4 4.7 28.9 2.2 2.2 1.0 0.62 YGL091C 2.1 1.2 2.5 3.1 0.7 1.0 1.4 1.8 0.96 -
TABLE 4 Energy system protein genes yeast The level of expressed mRNA in the presence of chemical substance/ genes (1) (2) (3) (4) (5) (6) (7) (8) (9) (10) YCR107W 12.1 2.6 1.8 1.6 0.7 1.5 1.5 15.6 196.6 34.0 YDL243C 14.5 2.7 2.4 1.0 1.1 2.2 1.6 11.8 64.2 29.6 YFL056C 19.0 2.3 2.3 1.5 0.9 0.6 1.4 18.5 162.3 31.3 YFL057C 20.9 5.9 1.5 1.8 0.9 1.2 1.8 18.0 51.8 46.1 YJR155W 7.6 3.7 1.4 2.5 0.7 1.4 1.7 10.6 38.2 18.8 YNL331C 8.6 3.6 1.3 1.0 1.6 1.8 1.9 13.1 42.6 36.3 YOL165C 10.1 4.5 1.8 0.9 0.9 1.7 1.4 17.8 46.9 23.3 YPL171C 15.2 4.1 3.5 2.2 1.1 1.3 1.7 20.5 60.0 50.6 YDL021W 5.1 1.7 2.4 3.7 1.7 6.5 5.9 2.7 2.5 7.4 YGR043C 2.6 3.7 3.2 7.9 0.9 16.3 6.5 2.6 10.9 8.4 YHR179W 3.3 2.3 2.6 0.7 1.2 3.7 1.9 3.3 3.6 5.8 YJR048W 1.3 0.9 2.2 1.4 0.8 0.5 0.3 0.9 0.5 1.5 YKR097W 1.6 2.4 1.3 3.3 1.1 1.7 3.7 2.5 1.9 3.3 YML087C 1.8 1.6 0.8 2.5 0.9 0.9 1.1 1.3 1.9 4.9 YPL088W 3.3 1.3 0.6 2.5 1.5 7.1 3.7 1.9 0.6 2.8 YDL174C 0.9 1.8 0.9 1.3 0.5 1.7 3.6 0.8 0.5 1.7 YCR012W 1.2 1.5 5.1 1.2 1.1 2.5 1.4 0.8 1.4 1.5 YFR053C 1.8 1.4 3.0 2.2 0.9 3.2 2.1 2.8 0.6 1.1 YGL062W 0.6 1.3 1.1 0.6 0.9 1.0 1.3. 0.8 1.6 2.5 YGR192C 1.4 1.0 3.8 1.0 1.1 1.7 1.7 1.1 0.9 1.3 YGR244C 1.0 1.2 1.6 1.6 0.8 2.6 3.9 1.8 1.4 1.1 YGR254W 1.2 1.3 3.8 1.3 1.2 1.9 1.5 1.4 0.8 1.2 YIL160C 0.8 2.4 2.3 3.5 1.0 1.6 1.1 1.2 3.2 3.8 YJL052W 1.6 0.9 4.0 1.8 0.7 2.4 2.1 1.5 1.6 2.0 YJR009C 1.1 1.7 5.6 1.0 1.2 1.6 1.6 1.1 1.1 1.3 YLR345W 1.4 1.4 1.4 1.2 1.2 1.6 1.2 1.4 4.5 4.0 YMR118C 1.3 2.9 1.4 1.6 1.2 2.0 1.0 1.0 9.3 1.4 YNL071W 0.9 0.9 1.7 1.5 0.6 1.3 1.4 0.9 1.1 1.2 YNL241C 1.3 2.5 4.3 1.0 0.8 0.9 3.2 0.9 3.4 7.4 YPL240C 0.7 1.4 2.4 0.9 1.3 1.2 1.4 1.2 3.5 2.6 YAL060W 1.1 1.8 3.2 2.7 1.2 4.2 3.3 0.9 0.6 2.5 YCL040W 0.9 5.6 10.1 2.0 0.5 3.5 2.9 0.7 0.9 3.0 YDR001C 1.0 2.2 2.6 1.0 1.1 2.2 1.5 0.9 2.2 3.0 YDR231C 1.1 1.6 1.0 1.5 1.1 2.2 1.7 1.3 1.5 1.4 YER178W 0.8 0.9 3.6 1.0 0.7 2.5 1.6 0.8 1.7 1.3 YGR008C 2.4 3.0 1.7 3.2 0.9 2.9 3.7 1.9 3.1 2.4 YGR256W 1.2 1.5 2.3 0.8 0.9 6.2 1.4 2.2 3.4 2.5 YHL008C 0.9 0.5 1.0 1.6 0.8 0.8 0.7 0.9 1.6 1.7 YHR174W 1.1 1.4 3.3 1.2 1.3 1.5 1.6 1.2 1.0 1.5 YIL045W 1.7 1.4 1.9 2.2 1.3 1.7 1.6 1.1 2.1 3.2 YKL035W 1.0 0.9 4.8 1.2 0.8 1.2 0.6 1.0 0.8 1.2 YKL152C 1.4 1.3 1.9 0.9 1.3 1.6 1.5 1.0 0.9 1.5 YML054C 1.5 1.8 1.3 3.4 1.3 1.8 1.2 1.5 4.1 1.8 YML100W 0.8 2.7 10.6 1.4 0.9 2.8 2.2 0.7 1.7 1.4 YML125C 0.8 0.9 0.7 0.7 0.9 1.3 1.0 1.3 2.6 1.6 YMR089C 1.0 1.1 0.9 0.9 0.8 1.2 1.2 1.3 5.6 2.5 YMR105C 2.0 3.0 5.0 4.2 0.9 2.8 2.8 1.1 0.6 2.9 YNL237W 1.3 1.3 1.5 1.0 1.5 4.6 4.9 1.1 0.9 2.1 YOL126C 1.1 0.8 1.0 1.6 0.7 1.5 1.4 0.9 0.8 2.4 YOR347C 0.9 0.9 2.1 2.2 0.7 0.9 0.9 0.8 0.5 0.9 YPR026W 0.9 1.2 5.0 1.3 0.8 1.3 1.0 0.9 3.1 YAL038W 1.0 1.0 3.0 1.4 1.4 1.3 0.9 1.1 0.1 1.1 YDR380W 0.8 0.8 0.8 1.7 1.1 0.4 0.5 0.2 0.2 0.3 YLR273C 1.5 1.0 1.3 2.4 1.2 1.2 1.3 2.8 2.4 YGR207C 1.5 1.1 1.0 1.1 1.5 2.8 1.7 1.9 2.1 2.6 YNL037C 1.4 1.8 1.7 1.1 1.7 2.8 2.8 1.0 0.6 3.2 YOR136W 1.0 0.9 3.5 1.0 1.5 3.9 3.2 1.1 0.3 3.4 YPL271W 1.2 3.2 4.1 1.2 1.4 3.3 1.2 0.9 0.6 1.2 YAL054C 1.2 1.1 1.4 1.6 1.1 2.2 1.1 1.1 8.9 4.1 YEL011W 2.0 1.6 1.7 6.3 1.1 2.8 2.7 0.9 2.5 1.6 YFR015C 1.2 0.8 3.2 2.1 1.2 3.0 7.3 0.7 0.3 1.8 YGL253W 0.8 1.0 3.2 0.7 1.3 2.4 1.7 1.1 0.3 1.4 YIL111W 1.9 1.0 1.8 2.7 2.6 3.2 1.2 1.6 1.1 YKL150W 1.1 2.0 3.0 1.4 1.4 2.3 2.4 1.3 1.1 1.3 YPR006C 1.9 1.5 0.5 1.9 2.0 2.4 2.8 1.5 1.5 3.9 YBR145W 1.5 0.7 2.8 0.9 1.1 11.5 58.8 1.0 0.1 1.1 YBR299W 2.0 0.9 1.1 3.5 1.6 0.8 3.6 2.2 1.1 5.3 YEL020C 1.0 1.5 0.8 2.9 1.5 1.3 2.4 1.2 1.4 1.1 YGL134W 1.2 1.3 0.5 0.8 1.4 1.2 2.3 1.4 1.1 1.4 YOL157C 1.0 1.1 1.3 2.5 1.4 0.9 2.7 1.4 2.3 4.8 YBR126C 0.8 1.9 5.6 1.2 0.7 2.9 2.3 0.6 1.7 YCR005C 1.2 1.9 2.0 1.2 0.9 1.6 4.4 1.2 1.5 1.5 YIL172C 1.1 1.1 1.6 1.7 1.3 2.5 1.6 2.8 7.1 YOR221C 0.8 1.0 0.9 1.1 1.7 0.8 2.1 0.9 1.4 1.7 YBR196C 0.8 0.6 3.9 1.4 0.8 0.8 1.4 1.1 0.3 0.9 YEL047C 1.3 1.9 3.2 1.2 0.8 0.6 1.3 1.0 2.7 2.3 YMR318C 1.8 2.4 2.2 0.7 1.2 2.1 0.8 3.6 2.3 4.8 YER061C 0.9 0.9 1.2 2.5 0.8 0.4 0.9 0.7 0.3 0.7 YJL045W 1.8 2.2 1.6 5.3 0.7 0.6 0.7 0.9 9.7 1.6 YLL009C 1.0 1.2 0.6 1.9 1.5 1.2 1.7 1.0 1.3 1.7 YPR160W 1.4 3.8 3.6 3.3 0.7 4.5 1.8 0.9 0.9 1.3 YDL085W 1.2 1.9 1.2 2.0 1.2 1.2 1.4 1.0 7.8 3.4 YJL221C 1.1 1.0 1.1 1.3 0.9 6.6 2.5 1.8 2.7 4.4 YKL085W 1.5 2.3 1.6 1.2 1.2 1.9 1.5 1.2 1.9 3.0 YLR174W 1.2 1.5 1.7 2.1 0.9 0.9 1.6 1.1 2.5 8.3 YNL009W 1.1 1.9 2.0 1.4 1.4 1.1 1.2 1.1 1.4 3.3 YNL117W 0.9 4.7 1.7 0.8 0.8 1.1 1.7 12.8 4.4 YAL061W 1.7 2.4 3.3 3.8 1.0 1.0 2.0 0.8 5.5 1.4 YBR117C 0.8 1.6 1.5 1.4 0.9 2.3 1.0 0.7 5.9 1.5 YEL071W 1.1 1.6 2.6 0.4 1.3 1.9 2.0 1.2 3.6 2.8 YGR112W 1.0 2.9 1.1 1.3 0.9 1.1 1.3 1.3 2.6 1.3 YLR164W 1.0 2.4 0.3 1.0 1.2 1.2 1.1 1.2 5.3 2.0 YNR032W 1.0 1.5 1.0 2.1 1.5 1.0 1.1 1.0 6.2 2.4 YPL031C 0.9 2.0 1.4 0.8 1.5 1.8 1.6 1.0 5.7 1.4 YPR048W 1.3 2.0 0.9 1.1 0.9 0.6 0.9 1.5 4.0 2.1 YBL058W 0.9 1.5 0.5 1.1 1.6 0.9 1.5 1.2 2.6 2.1 YBR001C 0.9 1.4 1.1 1.4 0.9 1.1 0.9 1.3 2.3 2.1 YCR105W 2.2 1.2 1.2 3.0 0.9 1.0 1.0 1.4 2.0 3.9 YIR031C 0.9 1.6 0.6 0.6 1.6 1.7 1.4 1.0 2.6 1.0 YGL191W 2.3 1.6 1.4 1.8 0.9 1.6 1.0 1.6 1.1 1.3 YLR038C 2.6 1.1 0.6 2.1 1.8 1.2 1.0 1.4 0.4 0.9 YGR087C 1.0 15.0 1.7 0.6 1.0 1.1 1.0 0.8 0.2 0.9 YGL256W 0.9 5.3 1.1 1.3 0.7 0.7 0.5 1.0 0.4 1.2 YDL181W 1.4 1.8 1.9 1.8 1.7 1.2 1.1 0.6 0.7 0.8 YPL262W 1.1 1.7 3.8 1.2 0.6 1.6 1.3 1.0 1.4 5.8 YLR377C 1.1 2.6 1.8 1.2 1.0 0.7 0.9 0.7 1.8 1.6 YBR221C 0.8 0.7 3.2 1.5 1.3 1.7 1.5 0.8 1.0 1.3 YKL141W 1.6 1.1 4.7 1.7 1.5 1.2 0.5 0.8 0.8 0.5 YLR134W 0.9 0.6 2.3 0.8 1.3 2.5 1.1 0.8 0.1 0.7 YLR258W 1.7 1.0 4.2 3.5 0.9 1.8 1.8 0.9 0.8 1.3 YOR178C 1.4 1.3 4.8 2.3 1.0 2.7 0.9 0.9 0.2 1.7 YBL099W 0.8 0.9 3.1 1.4 1.0 0.9 0.9 0.8 0.9 0.7 YDR050C 1.9 1.3 2.3 1.8 0.9 1.7 1.5 1.3 0.4 1.3 YDR178W 2.0 2.0 3.4 2.2 0.9 2.1 0.6 0.9 0.9 0.8 YDR298C 1.3 1.2 2.6 1.3 1.3 1.2 1.0 1.2 1.0 1.6 YEL024W 1.5 0.9 3.8 1.1 1.3 1.1 0.7 1.0 0.7 0.6 YJL121C 1.0 0.5 1.9 0.8 1.0 1.1 0.7 1.0 0.1 0.4 YJR121W 1.2 1.1 3.3 1.0 0.8 1.5 1.0 0.7 0.8 1.3 YKL060C 1.7 0.8 2.5 1.0 1.6 1.3 1.2 1.1 0.3 0.8 YKL148C 0.9 0.8 3.7 0.7 0.8 0.5 0.6 0.8 1.7 1.7 YLL041C 1.5 0.5 4.6 1.0 1.6 1.2 0.3 0.8 0.7 0.8 YLR044C 0.8 0.6 2.2 0.9 1.7 1.5 1.3 0.7 0.0 1.2 YLR284C 0.9 1.0 3.8 1.9 1.6 0.9 0.8 1.2 0.9 0.9 YLR304C 0.7 0.6 5.0 0.7 0.6 1.9 0.6 0.6 0.1 2.2 YLR354C 1.2 2.5 2.3 1.5 1.6 1.5 1.1 1.4 0.4 0.9 YMR205C 0.5 0.7 2.3 0.8 1.2 1.2 0.9 0.7 0.3 0.8 YMR261C 0.8 1.6 3.6 0.8 0.9 0.6 1.3 0.7 1.6 1.3 YMR323W 0.8 1.1 2.9 1.1 0.7 0.4 1.1 0.8 0.5 1.3 YOL086C 1.1 0.5 2.2 1.1 1.9 1.7 1.9 0.8 0.1 1.2 YOR142W 1.3 1.2 3.4 1.0 1.4 1.6 1.0 0.8 1.1 1.5 YPL061W 0.4 1.4 5.0 1.3 1.6 1.7 0.5 0.8 1.3 0.7 YDL107W 1.3 1.3 1.0 2.2 1.0 1.3 1.8 1.8 1.2 1.8 YDR529C 1.8 1.0 0.9 3.2 1.2 0.8 0.5 1.3 0.5 0.6 YGL018C 1.5 1.0 1.8 3.0 1.1 0.4 1.1 0.8 0.5 1.4 YBR185C 1.5 1.0 1.3 2.0 0.8 1.2 1.2 1.1 0.9 1.6 YEL039C 1.1 0.7 1.3 5.1 0.9 1.5 0.6 1.1 1.2 1.2 YGR174C 1.1 1.6 0.6 2.4 1.0 1.4 1.0 1.6 1.8 0.7 YKL016C 1.5 1.3 0.7 1.7 1.5 0.8 1.5 1.6 1.3 1.8 YLR395C 1.8 1.3 2.2 1.9 0.7 0.4 1.0 1.0 0.9 YML120C 1.1 1.2 1.9 1.9 0.6 0.6 0.8 0.9 1.3 1.5 YMR073C 1.1 1.1 1.2 1.5 0.8 0.9 1.0 1.1 1.2 1.2 YOR388C 1.0 1.6 1.3 4.7 1.3 1.4 1.0 0.7 0.1 1.4 YPL275W 0.6 1.5 1.3 5.1 1.2 1.0 1.1 1.0 0.2 1.2 YPL276W 1.2 1.5 1.6 3.0 1.5 1.1 1.2 0.9 −0.2 1.8 YGL205W 1.0 0.9 0.7 0.8 1.1 1.6 0.8 1.2 0.5 0.6 YJL166W 2.1 1.5 1.6 1.3 1.6 0.7 0.8 1.4 1.3 1.2 YNL202W 0.7 1.3 1.2 1.7 0.9 2.0 0.9 1.2 1.3 1.1 YDR377W 1.3 1.1 1.3 1.4 1.9 1.3 1.1 1.3 1.0 0.9 YGL187C 1.5 0.8 1.6 1.8 1.3 1.1 0.6 0.7 0.6 0.6 YJL216C 1.1 4.7 2.2 0.9 0.8 1.5 1.9 1.5 1.3 YKR009C 1.0 1.2 1.5 0.9 1.0 1.8 1.0 0.9 2.4 2.1 YCR046C 1.0 1.2 1.2 1.6 1.0 0.8 1.2 0.9 1.9 1.4 YML129C 1.1 0.9 0.9 1.2 1.7 1.7 1.8 1.2 1.4 2.2 YPR184W 1.2 1.4 5.7 2.2 0.9 1.5 1.3 0.7 1.9 3.2 YDL067C 1.8 1.0 1.6 1.3 2.0 0.9 0.8 1.1 0.9 0.9 YDL078C 0.7 1.1 1.2 0.8 1.3 1.1 1.7 1.0 1.1 1.0 YDR079W 1.3 1.1 0.8 1.1 1.2 1.7 1.3 2.6 0.9 0.8 YGR062C 0.9 1.0 0.7 1.4 0.7 0.9 1.3 0.8 1.0 1.4 YKR058W 1.3 0.9 1.4 1.9 0.8 1.4 1.4 1.5 1.3 1.2 YLR295C 1.5 1.1 1.1 1.7 2.2 1.1 1.1 1.2 1.4 1.2 YMR267W 0.8 1.8 0.7 0.9 1.0 1.4 1.2 1.5 0.4 0.8 yeast The level of expressed mRNA in the absence of chemical substance genes (11) (12) (13) (14) (15) (16) (17) (18) Intensity YCR107W 23.0 0.9 4.0 8.3 4.8 3.1 1.3 1.1 0.59 YDL243C 19.6 1.1 4.1 12.0 4.2 3.0 1.8 1.5 0.76 YFL056C 68.3 1.0 4.7 7.8 5.0 3.4 1.0 1.1 0.55 YFL057C 27.7 1.0 4.1 23.4 3.1 3.9 1.6 1.3 0.71 YJR155W 15.4 1.0 5.7 9.4 2.6 5.6 1.3 1.4 0.64 YNL331C 21.8 0.9 3.1 7.5 2.3 4.0 1.7 1.3 0.58 YOL165C 17.6 0.8 3.7 9.1 3.0 1.8 1.6 1.0 0.69 YPL171C 37.0 1.4 2.4 9.3 1.4 1.2 2.4 1.5 0.47 YDL021W 4.7 2.4 5.3 3.7 0.7 7.3 1.9 3.2 0.47 YGR043C 3.6 3.3 6.9 4.1 3.0 13.7 1.6 4.8 0.66 YHR179W 2.0 2.2 2.6 5.8 2.7 1.0 1.9 1.6 2.69 YJR048W 1.0 0.8 0.4 2.5 0.6 1.5 1.2 1.2 1.19 YKR097W 0.8 1.8 17.5 2.1 2.5 2.2 1.1 1.5 0.16 YML087C 1.6 0.8 1.5 2.1 0.3 2.0 0.7 0.8 0.52 YPL088W 1.1 3.6 4.8 1.6 3.2 4.3 9.1 8.3 0.69 YDL174C 0.9 2.8 5.9 1.1 0.6 5.1 2.2 4.0 0.63 YCR012W 1.8 1.2 4.1 0.9 1.4 1.4 0.8 1.3 4.48 YFR053C 1.5 1.7 3.0 0.6 0.6 3.0 1.4 2.2 4.17 YGL062W 0.7 1.6 4.5 1.2 2.7 1.5 1.1 0.9 0.77 YGR192C 2.3 2.2 3.4 1.0 1.9 1.1 1.1 1.3 7.49 YGR244C 1.8 1.9 2.6 1.2 2.0 2.6 1.9 3.1 1.12 YGR254W 1.3 1.7 3.1 0.6 2.4 1.4 1.3 1.2 7.01 YIL160C 2.4 1.0 2.3 1.5 5.6 8.8 2.4 3.0 0.27 YJL052W 4.3 2.4 5.6 1.3 2.3 2.3 1.2 1.9 6.19 YJR009C 1.1 1.5 2.7 1.0 2.1 1.5 1.1 1.3 5.86 YLR345W 2.5 1.6 3.5 1.5 1.0 1.2 1.2 1.4 2.65 YMR118C 0.7 0.8 4.2 0.9 0.9 8.1 0.8 1.0 0.38 YNL071W 1.6 1.3 2.5 0.8 1.1 1.1 1.0 1.2 1.61 YNL241C 3.0 2.0 4.9 1.1 7.0 2.8 1.0 1.0 0.68 YPL240C 1.0 0.8 2.9 0.7 1.2 0.7 0.8 1.0 4.83 YAL060W 2.4 0.8 2.2 0.9 0.9 3.2 1.1 1.8 2.39 YCL040W 8.2 2.3 5.6 0.7 3.4 3.1 1.4 1.7 1.98 YDR001C 0.7 1.1 2.8 1.0 4.4 1.9 1.1 1.6 0.75 YDR231C 1.3 1.1 2.4 1.5 1.0 3.0 1.2 1.3 0.92 YER178W 2.5 1.3 2.4 0.9 1.8 1.0 1.1 0.9 2.18 YGR008C 2.6 2.0 3.4 1.3 1.5 2.3 1.7 4.2 3.03 YGR256W 2.7 1.5 3.9 1.1 2.7 5.3 1.1 0.8 0.94 YHL008C 1.4 0.8 1.8 1.0 1.8 0.9 0.8 0.9 0.40 YHR174W 1.4 1.5 3.6 0.6 2.0 1.1 1.0 1.2 7.34 YIL045W 1.2 1.5 2.0 1.6 0.6 2.9 1.1 1.8 0.37 YKL035W 2.1 1.0 2.0 0.6 1.0 1.5 1.0 1.9 2.54 YKL152C 1.7 1.5 2.7 1.0 1.8 2.0 1.1 1.7 3.28 YML054C 1.4 1.8 2.8 2.1 1.1 7.8 1.1 1.6 0.25 YML100W 3.2 1.2 3.8 1.2 1.8 2.2 1.0 1.5 0.88 YML125C 1.0 1.0 2.2 1.6 1.9 0.7 1.2 0.9 2.21 YMR089C 1.3 0.8 2.3 0.9 1.8 1.1 0.9 1.1 0.69 YMR105C 3.0 1.7 3.3 1.0 0.9 2.0 1.6 2.6 1.21 YNL237W 1.5 1.8 3.2 1.3 1.6 4.4 1.3 1.1 0.21 YOL126C 1.8 1.1 2.6 1.2 1.4 2.5 1.6 2.4 0.59 YOR347C 1.4 1.2 1.8 0.9 2.0 1.4 1.7 1.3 1.31 YPR026W 1.6 1.2 2.3 1.5 3.1 2.5 0.9 1.3 0.26 YAL038W 1.0 1.2 1.8 0.5 3.1 0.9 1.0 1.0 7.02 YDR380W 0.4 0.4 0.4 0.6 2.4 0.2 0.8 0.8 1.04 YLR273C 1.4 0.9 1.7 1.3 2.6 1.5 1.0 1.0 0.20 YGR207C 1.4 1.1 1.0 2.2 0.6 1.8 1.2 1.8 1.49 YNL037C 1.4 1.3 1.9 1.3 0.9 1.4 0.9 1.3 2.05 YOR136W 1.4 1.2 1.5 0.9 1.2 1.3 0.8 1.3 3.20 YPL271W 1.7 0.8 1.2 1.3 0.8 1.4 1.2 1.3 1.34 YAL054C 1.3 1.0 1.8 1.3 0.9 2.5 1.5 1.4 0.24 YEL011W 3.7 1.5 1.5 1.5 0.4 2.4 1.4 2.5 0.89 YFR015C 3.9 0.4 2.5 3.1 0.4 2.4 1.3 1.2 0.66 YGL253W 1.0 1.2 1.5 0.5 0.8 0.4 0.7 0.8 4.63 YIL111W 2.1 0.9 1.7 1.5 1.1 2.5 1.9 3.9 1.52 YKL150W 1.9 1.2 1.8 1.4 0.9 6.1 1.2 2.7 2.20 YPR006C 2.4 1.1 1.8 1.2 0.7 1.6 1.8 2.1 0.46 YBR145W 1.1 1.0 2.0 2.2 1.2 3.6 1.7 2.0 2.17 YBR299W 2.4 1.2 0.7 1.4 0.6 3.9 1.0 1.1 0.32 YEL020C 1.3 0.8 1.2 1.0 1.4 2.1 1.2 1.3 0.31 YGL134W 1.1 0.9 0.7 1.1 0.5 1.7 0.9 1.3 0.53 YOL157C 1.2 1.2 1.4 1.2 1.1 3.5 1.4 1.3 0.41 YBR126C 1.1 1.3 2.1 0.7 1.0 1.7 1.5 1.3 1.96 YCR005C 2.1 0.5 0.7 0.8 0.7 0.7 1.6 1.7 2.38 YIL172C 1.0 1.4 2.0 1.3 1.4 2.8 1.1 1.2 0.42 YOR221C 1.1 0.8 1.0 1.1 1.0 1.4 0.9 1.2 0.39 YBR196C 2.3 1.0 1.4 0.5 1.9 1.1 0.8 1.0 6.60 YEL047C 4.2 1.2 1.6 1.1 1.0 1.3 0.9 1.0 1.02 YMR318C 3.6 0.8 1.8 1.7 1.5 1.1 1.1 1.1 3.17 YER061C 2.2 0.7 0.9 1.0 0.8 1.8 1.2 1.2 0.84 YJL045W 2.3 1.1 1.6 1.2 3.4 2.4 0.9 0.9 0.42 YLL009C 3.5 0.7 0.9 1.4 1.1 2.8 0.9 1.2 1.66 YPR160W 4.4 2.1 2.2 1.1 1.4 5.3 1.0 2.9 1.42 YDL085W 2.7 0.8 1.7 1.2 0.7 4.5 0.9 0.9 0.23 YJL221C 0.8 1.1 1.4 1.1 1.1 3.3 1.1 1.4 0.41 YKL085W 1.8 0.8 1.5 1.0 0.5 1.7 0.9 1.3 2.16 YLR174W 1.3 1.3 1.8 1.7 0.8 4.6 0.9 1.2 0.41 YNL009W 1.3 0.9 1.3 1.3 2.7 3.3 1.2 2.3 0.45 YNL117W 1.4 0.7 1.3 2.0 2.6 1.6 1.1 0.9 0.24 YAL061W 4.1 1.1 1.4 0.7 0.6 1.1 1.4 1.2 0.88 YBR117C 0.4 0.8 2.1 0.9 1.0 12.0 0.7 0.7 0.49 YEL071W 2.1 0.9 1.6 1.2 1.6 1.2 1.1 1.2 1.13 YGR112W 1.3 0.7 1.1 1.1 1.2 2.8 0.9 1.2 0.31 YLR164W 3.2 0.7 1.0 1.5 0.7 11.0 1.5 1.2 0.31 YNR032W 1.4 0.6 1.3 1.4 0.9 1.0 1.2 1.3 0.71 YPL031C 1.4 0.8 1.6 0.9 0.7 2.0 1.4 1.2 0.49 YPR048W 1.0 0.8 0.6 1.2 0.6 0.8 0.7 0.8 0.75 YBL058W 1.3 0.8 1.6 1.3 1.8 1.8 1.0 1.4 1.42 YBR001C 1.0 1.0 2.0 1.2 1.8 1.4 1.0 1.6 0.61 YCR105W 2.3 0.9 1.9 1.9 3.1 1.3 1.3 1.1 0.36 YIR031C 1.2 0.8 1.0 1.2 0.8 0.7 0.9 0.8 0.44 YGL191W 1.6 0.9 1.1 1.6 0.7 1.8 1.2 1.7 2.35 YLR038C 1.4 0.6 0.5 1.6 0.7 2.1 1.2 2.1 1.52 YGR087C 0.8 1.2 1.2 0.7 3.5 0.6 1.0 0.6 1.88 YGL256W 1.0 0.9 0.8 0.9 1.0 0.7 0.7 0.8 0.90 YDL181W 0.8 0.9 0.9 1.1 0.4 1.1 1.5 1.4 0.85 YPL262W 1.4 1.1 1.5 1.2 0.6 1.4 1.1 1.2 0.79 YLR377C 0.6 0.6 1.2 2.9 0.8 2.7 0.9 1.4 0.14 YBR221C 1.2 1.3 1.7 0.8 1.1 1.5 0.9 1.0 3.62 YKL141W 1.2 0.8 0.8 1.4 0.6 2.8 0.9 1.8 2.84 YLR134W 1.1 1.2 1.5 0.6 1.7 0.5 0.6 0.8 3.47 YLR258W 1.2 0.9 1.4 1.2 0.6 1.7 1.0 2.0 1.36 YOR178C 4.1 1.7 1.0 1.0 1.1 1.7 1.0 1.5 0.56 YBL099W 2.1 1.0 0.9 0.6 1.0 0.9 0.7 1.2 3.49 YDR050C 2.0 1.4 2.0 1.2 1.9 1.3 1.1 2.3 6.26 YDR178W 2.0 1.3 1.5 1.5 0.7 3.0 1.2 2.3 2.27 YDR298C 1.2 1.1 1.2 1.5 0.8 2.0 1.1 1.6 2.69 YEL024W 0.9 0.8 0.6 1.1 0.6 2.1 1.1 1.5 1.59 YJL121C 1.1 0.6 0.7 0.9 1.0 0.6 1.1 1.0 1.00 YJR121W 0.9 0.8 1.0 0.7 0.9 1.2 1.1 1.4 3.99 YKL060C 2.1 1.3 1.2 0.8 1.6 1.5 1.2 1.7 6.01 YKL148C 1.5 0.8 0.8 0.8 0.6 1.1 0.8 1.0 0.54 YLL041C 1.3 0.8 1.0 1.2 0.4 3.1 1.1 1.7 1.75 YLR044C 1.1 1.4 1.7 0.5 2.2 0.6 0.9 0.9 5.16 YLR284C 1.5 0.6 0.8 1.3 1.0 4.5 2.9 8.1 0.84 YLR304C 1.6 1.0 0.5 0.7 1.6 1.8 0.5 0.7 2.39 YLR354C 1.7 1.2 1.0 0.9 2.4 1.3 1.0 1.5 4.53 YMR205C 1.0 1.1 1.3 0.5 0.9 0.9 0.6 0.5 4.75 YMR261C 0.8 0.9 1.6 0.6 0.8 1.6 0.7 1.1 0.78 YMR323W 2.5 1.2 1.8 1.2 37.3 0.6 1.1 0.6 1.04 YOL086C 2.6 1.3 1.7 0.6 1.6 1.4 1.1 1.3 4.19 YOR142W 1.5 0.8 1.4 0.8 1.1 0.8 0.9 1.0 1.31 YPL061W 1.1 1.0 1.1 0.6 1.7 1.0 1.6 2.6 3.23 YDL107W 1.0 1.0 1.2 1.5 1.0 2.0 1.1 1.5 0.51 YDR529C 0.8 0.6 0.7 1.5 0.5 1.8 1.0 2.3 3.11 YGL018C 1.1 1.0 1.3 1.2 1.1 1.5 0.8 1.0 0.36 YBR185C 1.2 0.7 1.0 1.7 1.0 1.7 0.8 1.3 0.89 YEL039C 1.7 0.6 0.5 1.4 0.4 3.5 0.7 1.1 1.59 YGR174C 1.3 0.9 1.5 1.6 0.7 3.2 1.3 2.3 1.05 YKL016C 1.3 1.0 1.3 1.6 0.7 1.8 1.0 1.7 2.08 YLR395C 1.5 0.6 0.5 1.7 0.4 1.2 1.2 2.3 1.76 YML120C 1.3 0.9 1.2 0.8 0.5 1.5 1.0 1.6 0.74 YMR073C 0.9 0.8 1.2 2.0 0.9 1.5 0.8 1.2 0.69 YOR388C 1.3 0.7 1.1 1.3 4.0 0.8 1.0 0.9 0.21 YPL275W 0.9 0.6 1.0 1.0 1.4 0.9 1.0 1.0 0.28 YPL276W −0.4 0.6 0.9 0.9 1.0 0.6 1.1 0.8 0.22 YGL205W 0.4 1.1 1.0 1.0 2.0 4.1 3.9 9.1 0.24 YJL166W 1.4 0.7 0.8 1.9 0.5 2.3 1.7 4.0 2.31 YNL202W 1.2 0.9 1.8 1.0 1.4 4.2 2.4 3.3 0.47 YDR377W 1.4 0.9 0.7 1.4 0.6 1.8 1.2 2.5 3.00 YGL187C 0.7 0.8 0.7 0.9 0.3 1.4 0.9 2.4 2.73 YJL216C 1.1 1.0 1.1 1.1 1.2 1.5 1.2 2.0 0.25 YKR009C 1.2 1.0 1.8 1.0 1.0 4.6 1.9 2.5 0.27 YCR046C 1.5 1.1 1.5 1.3 1.4 2.8 1.3 1.0 0.63 YML129C 1.2 0.8 1.0 1.4 1.1 2.9 1.3 1.3 1.04 YPR184W 3.6 1.4 2.5 1.3 1.5 3.1 1.0 1.7 0.37 YDL067C 1.4 1.0 0.6 1.4 0.7 1.8 1.2 1.7 1.85 YDL078C 1.7 0.8 1.0 0.8 0.5 2.2 1.1 2.0 1.65 YDR079W 1.3 1.1 1.3 1.5 0.6 2.6 1.1 1.3 1.06 YGR062C 1.6 1.0 1.5 1.2 0.5 1.8 0.9 1.1 0.54 YKR058W 1.5 0.9 0.7 1.3 0.5 2.6 0.8 1.6 0.73 YLR295C 1.3 0.5 0.8 1.2 0.5 2.4 0.9 1.5 1.07 YMR267W 1.0 0.8 0.7 1.0 0.9 2.6 0.9 1.3 0.94 -
TABLE 5 Transport facilitation protein genes yeast The level of expressed mRNA in the presence of chemical substance/ genes (1) (2) (3) (4) (5) (6) (7) (8) (9) (10) YBR008C 3.0 2.4 4.9 0.7 0.9 1.0 0.9 2.8 54.6 21.1 YBR296C 7.0 4.3 2.2 2.5 1.4 1.4 0.2 1.1 0.4 1.8 YDR406W 0.8 1.2 3.1 1.1 1.0 5.9 1.8 0.6 1.1 1.7 YOR153W 1.6 0.9 5.1 1.1 1.0 7.4 2.6 0.5 3.2 1.2 YGR281W 1.2 1.0 1.3 2.2 0.6 1.9 0.9 0.7 2.7 1.4 YHL047C 0.6 4.4 1.0 1.0 1.2 8.4 16.8 1.5 1.2 11.9 YBR294W 6.3 14.4 0.9 2.6 1.4 1.2 1.1 1.0 5.2 5.2 YGL006W 2.5 1.3 1.3 2.6 1.0 1.0 1.3 0.9 3.0 1.2 YGR197C 1.1 2.4 2.5 1.0 0.7 0.5 1.3 0.8 16.7 3.2 YJL034W 0.7 1.7 3.0 0.8 1.2 1.1 1.3 1.5 2.8 1.1 YNL055C 1.1 1.8 5.5 2.0 0.9 2.6 1.2 0.7 1.1 1.0 YBR052C 1.6 1.6 1.5 2.6 1.4 2.1 3.0 1.3 2.3 2.5 YBR207W 0.8 1.7 0.8 2.0 1.7 1.6 4.3 0.9 1.7 2.2 YBR293W 1.9 3.1 1.0 1.8 0.8 0.9 0.9 0.9 5.5 2.4 YDL198C 1.4 1.0 2.1 1.4 0.7 0.8 1.0 1.1 1.9 2.7 YDL245C 1.0 2.4 1.6 2.2 1.3 1.1 1.2 1.2 0.4 2.8 YDR497C 0.7 0.5 0.6 1.3 0.7 0.6 0.5 0.6 0.4 0.8 YER053C 1.6 1.8 1.9 1.7 0.6 2.8 2.8 1.3 1.3 3.9 YFL041W 0.7 1.6 1.4 1.2 1.2 2.0 3.4 1.0 0.8 5.1 YGR055W 2.5 5.7 12.0 0.7 1.3 1.1 0.6 1.1 5.0 2.4 YJL219W 1.2 2.5 3.1 1.6 1.2 1.5 0.9 1.5 4.0 2.3 YJR106W 0.9 3.8 1.5 1.1 0.9 1.2 1.0 0.9 2.0 1.6 YKL146W 0.8 1.3 1.3 0.9 1.0 1.3 0.9 0.8 4.6 2.8 YLL028W 0.6 0.9 4.6 0.5 0.9 1.7 1.0 0.7 1.2 2.3 YLR348C 1.1 4.5 1.2 1.2 0.9 1.9 0.9 0.9 2.1 1.3 YOL119C 2.6 4.8 1.5 2.3 1.5 0.9 2.2 2.0 5.0 7.4 YOL163W 1.5 3.2 2.1 3.3 0.9 0.5 0.9 1.1 7.5 6.2 YOR035C 1.2 1.2 0.3 1.2 1.0 1.9 1.3 1.0 1.3 1.7 YOR130C 0.8 1.7 1.4 1.0 1.8 1.6 1.3 0.8 2.0 1.7 YOR273C 0.7 1.0 1.7 1.0 1.1 0.4 0.4 0.6 0.6 0.5 YOR332W 1.1 1.0 1.0 1.0 0.9 1.8 0.9 1.5 1.8 1.1 YCR098C 1.6 3.0 1.7 2.0 1.4 1.6 1.2 1.0 1.4 2.4 YGR138C 1.1 1.6 1.0 1.2 0.8 0.8 0.7 1.0 0.5 1.0 YBR295W 1.4 1.5 3.3 1.1 0.8 1.6 0.9 1.2 3.3 YGL255W 0.7 0.9 0.9 0.8 1.4 1.1 1.0 0.7 0.3 5.0 YHL035C 0.7 1.3 0.9 1.9 0.9 4.1 1.7 1.1 0.6 4.6 YIL022W 0.8 0.7 1.1 1.6 0.8 1.2 0.7 0.8 1.1 1.3 YLR378C 0.7 0.9 2.6 0.5 1.0 1.2 0.7 0.5 1.1 0.7 YCL038C 1.6 1.6 1.4 1.6 1.2 3.2 1.5 1.2 1.1 0.9 YFL054C 1.6 1.1 1.4 2.2 1.3 2.4 1.1 1.5 2.0 2.3 YHL040C 1.6 4.9 1.5 0.4 1.1 7.3 4.0 1.5 1.1 11.3 YKR039W 1.4 3.5 1.3 1.7 1.0 2.8 1.0 1.0 1.9 2.0 YPL271W 1.2 3.2 4.1 1.2 1.4 3.3 1.2 0.9 0.6 1.2 YBR068C 1.1 1.0 1.9 2.5 1.4 1.9 1.0 0.8 2.5 YCR037C 0.7 1.0 0.8 0.8 1.3 1.8 1.0 0.7 0.6 0.6 YDL128W 0.8 1.1 2.1 1.0 1.0 2.3 0.9 0.8 0.5 0.7 YDR270W 0.7 1.5 1.4 1.3 1.0 2.2 1.7 1.2 2.9 3.6 YEL065W 0.3 3.8 1.2 0.4 1.4 2.3 4.3 0.9 0.1 4.9 YGL008C 0.6 0.7 3.1 0.9 0.8 1.9 1.4 0.7 0.0 0.4 YGL104C 0.8 2.0 2.1 1.8 1.0 2.1 1.2 0.8 4.6 2.1 YGL167C 0.9 0.7 1.6 1.3 1.2 2.0 1.2 0.8 1.3 1.1 YGR065C 0.8 1.5 2.6 1.1 1.2 2.4 2.4 1.0 1.2 2.6 YHR092C 2.3 1.0 7.5 2.5 1.4 1.7 0.5 1.5 0.2 0.9 YIL088C 0.9 2.1 2.1 1.3 1.6 2.2 1.7 0.8 1.0 1.7 YNL259C 1.6 3.5 1.1 1.2 1.1 3.9 3.8 1.5 1.6 2.1 YOR270C 0.7 0.5 2.0 0.8 0.8 1.8 1.0 0.6 0.4 0.9 YPL265W 0.7 0.4 2.3 1.1 1.0 2.3 8.9 2.3 0.2 1.2 YPR124W 0.2 0.4 0.3 1.4 2.0 2.0 2.9 2.7 0.2 1.5 YER119C 0.7 2.1 1.8 0.7 0.8 1.3 0.8 0.6 5.8 1.2 YFL055W 2.0 6.7 1.3 2.5 1.5 1.1 1.4 1.3 23.9 6.5 YLL055W 2.6 19.0 4.8 1.7 1.0 1.4 1.7 1.4 19.1 14.0 YHL036W 2.2 4.8 3.4 2.0 1.3 1.3 1.0 1.2 9.0 4.4 YHR048W 2.5 1.4 1.4 1.7 1.0 0.8 0.8 1.9 4.5 2.7 YKL221W 1.3 0.7 2.0 1.0 1.0 0.9 1.3 1.2 7.3 2.7 YLR092W 5.0 5.6 1.4 0.6 1.3 1.0 1.3 1.5 12.7 5.8 YML116W 4.1 1.3 1.5 1.4 1.2 0.9 1.4 2.2 1.4 3.1 YBR291C 2.0 0.9 1.0 1.5 0.9 1.1 0.9 2.2 0.9 1.0 YCL069W 0.9 4.5 0.9 0.8 0.9 1.4 1.3 1.2 6.9 YJR095W 1.2 20.5 1.9 6.7 1.2 1.5 2.0 0.9 0.5 6.3 YKL188C 1.3 0.7 1.9 2.4 1.0 0.8 1.1 0.7 2.5 2.8 YKL217W 1.8 2.4 1.0 2.1 1.1 1.2 1.6 1.1 0.9 4.1 YKR105C 0.8 0.9 0.9 1.5 1.0 1.2 1.0 1.3 1.0 5.2 YOL158C 0.7 4.0 2.4 0.9 1.2 2.0 1.6 0.7 1.7 6.1 YPL224C 1.0 2.2 1.3 2.5 0.6 1.3 2.2 1.3 3.2 4.2 YPR201W 33.2 0.9 1.1 1.0 1.2 1.9 0.8 0.9 8.3 5.6 YAL067C 2.7 12.1 1.5 1.4 0.7 1.2 0.8 1.1 7.6 2.9 YDL149W 0.8 2.0 1.2 1.6 1.5 1.0 0.7 1.2 3.2 2.0 YJL094C 1.0 1.7 1.3 2.0 1.4 1.3 1.7 0.8 5.4 2.9 YLL061W 3.6 2.8 9.2 0.4 0.8 0.8 0.9 1.4 3.7 5.5 YPL274W 0.8 4.2 3.8 0.8 0.6 1.1 0.7 0.9 4.1 3.6 YBR241C 0.9 9.3 2.6 0.9 0.9 1.5 1.4 0.7 29.8 2.2 YDL206W 0.9 1.7 1.8 1.4 1.1 5.7 2.0 1.1 1.6 1.5 YDR040C 0.7 1.4 3.7 0.8 1.0 1.7 0.7 0.8 2.0 1.2 YFR045W 1.1 1.6 1.1 1.1 1.0 1.0 0.6 1.0 2.2 1.0 YIL170W 1.1 1.0 2.5 2.2 0.9 8.8 0.5 1.2 5.7 3.2 YKL192C 1.1 1.0 3.7 1.1 1.1 1.8 1.1 0.9 3.5 1.6 YKL209C 1.0 1.0 1.3 0.8 1.2 3.3 0.9 1.4 2.4 1.6 YKR106W 1.3 0.8 2.1 1.4 1.2 1.6 0.9 1.3 10.5 7.4 YMR056C 1.1 1.3 1.7 1.0 1.1 0.9 1.4 1.2 1.8 1.1 YPL147W 1.0 0.8 2.3 1.2 1.2 1.1 1.0 0.9 2.4 2.4 YIL166C 1.9 12.5 2.1 1.2 1.0 1.9 1.3 2.5 2.9 YMR058W 0.3 5.1 2.1 0.3 0.8 2.6 1.8 0.8 0.2 1.4 YNL142W 0.7 2.4 2.5 0.8 1.3 0.9 1.1 0.8 0.9 0.6 YDL210W 1.2 2.2 2.7 1.1 0.9 1.3 0.8 1.1 1.2 1.4 YCL025C 1.1 4.6 2.5 1.7 0.9 0.9 0.7 0.7 0.3 0.3 YJL212C 0.8 3.2 3.1 0.5 1.2 1.1 0.7 0.7 1.1 1.3 YBR132C 0.9 1.9 2.4 1.8 0.8 1.2 1.1 0.8 0.8 1.1 YBL030C 1.0 0.9 4.5 0.9 0.7 1.1 0.9 0.8 0.4 0.9 YCR024C-A 0.8 0.9 3.2 0.9 1.2 0.8 0.8 0.2 0.7 YDR342C 2.8 1.1 12.2 5.7 1.6 1.1 0.8 1.2 0.2 2.2 YDR343C 1.2 1.0 20.6 4.6 1.3 1.3 0.7 1.2 0.3 2.1 YEL027W 1.2 0.6 3.4 1.1 1.0 1.1 0.8 0.9 0.9 1.1 YHR094C 0.7 1.2 5.3 1.6 1.1 1.6 0.8 1.2 0.3 1.2 YHR175W 0.8 2.0 2.4 1.5 0.9 1.0 1.6 0.9 0.6 2.0 YIL056W 1.1 0.9 6.2 1.4 1.2 1.0 0.6 0.7 1.2 1.6 YMR203W 0.8 0.7 3.0 1.4 0.6 1.1 0.8 0.7 0.7 1.2 YBL099W 0.8 0.9 3.1 1.4 1.0 0.9 0.9 0.8 0.9 0.7 YBR127C 0.8 0.7 2.2 1.1 1.4 1.1 0.9 1.1 0.6 1.3 YDR038C 0.6 1.3 3.1 0.9 0.9 1.8 0.7 0.9 1.4 0.9 YDR039C 0.6 1.6 3.2 0.9 1.3 1.1 0.8 0.6 1.8 1.0 YDR298C 1.3 1.2 2.6 1.3 1.3 1.2 1.0 1.2 1.0 1.6 YDR345C 0.8 0.9 5.6 2.6 1.3 1.2 1.1 1.2 0.2 1.1 YEL063C 0.7 0.8 2.4 1.3 1.2 1.3 0.7 0.6 0.8 1.7 YFL011W 1.2 0.7 3.7 3.3 1.3 1.0 0.8 0.8 0.3 1.6 YGR082W 1.0 0.9 2.2 1.0 0.9 1.1 0.9 0.8 0.6 0.9 YGR191W 0.8 0.7 1.6 1.5 0.8 1.1 0.7 0.7 0.1 0.7 YGR260W 0.6 0.7 3.4 0.8 0.8 0.9 0.9 0.5 0.3 0.4 YHR026W 0.9 1.0 1.9 1.0 1.1 1.3 0.9 1.6 1.1 0.9 YJR077C 1.1 1.1 2.0 1.6 0.9 0.9 0.7 0.8 0.4 0.7 YJR121W 0.9 1.1 3.3 1.0 0.8 1.5 1.0 0.7 0.8 1.3 YLR081W 1.3 0.8 2.8 3.6 1.0 0.9 0.7 0.9 0.1 2.2 YMR011W 1.3 1.0 9.4 5.5 0.9 0.6 0.8 1.1 0.0 0.7 YOL156W 1.1 0.7 2.5 1.1 1.2 1.2 1.0 1.0 2.3 2.1 YPL036W 0.5 0.8 2.8 0.9 1.3 0.7 0.3 0.5 0.1 0.3 YGR096W 1.5 1.0 1.1 4.6 1.2 1.7 0.9 1.0 0.8 0.8 YIL006W 1.0 1.1 1.4 2.9 0.8 0.3 0.8 0.6 0.9 1.1 YKL016C 1.5 1.3 0.7 1.7 1.5 0.8 1.5 1.6 1.3 1.8 YKR067W 0.8 2.6 1.5 2.5 1.3 1.8 2.0 0.8 1.6 2.3 YMR162C 0.8 1.1 1.1 2.0 0.9 1.0 0.8 0.8 0.7 1.0 YOR348C 1.1 0.7 1.2 2.0 0.9 0.7 0.8 0.8 0.5 0.4 YPR192W 0.9 1.1 0.9 5.0 1.2 0.9 0.9 0.6 0.7 1.3 YPR194C 2.2 1.4 0.5 2.9 1.3 1.5 0.7 1.0 0.5 0.6 YDR086C 1.3 1.0 1.2 1.4 1.0 0.8 2.0 1.9 0.6 0.8 YGR224W 0.9 1.2 1.2 1.2 1.4 0.8 0.4 0.6 0.9 0.9 YDR387C 0.8 0.9 1.2 2.2 0.9 1.2 1.3 0.7 1.4 2.0 YFL050C 0.7 1.0 1.1 2.2 1.0 0.9 0.8 0.9 0.5 1.6 YBR298C 1.1 1.0 1.6 2.3 1.4 0.4 1.7 0.5 0.3 1.1 YLR295C 1.4 1.1 1.1 1.7 2.2 1.1 1.1 1.2 1.4 1.2 YNR072W 1.1 1.5 0.5 0.7 1.0 0.9 1.5 0.9 0.7 1.8 YOR316C 0.7 2.5 1.5 1.5 1.0 0.9 1.4 0.8 1.6 2.0 YOR328W 1.0 1.0 1.0 1.0 2.9 YPL134C 1.5 1.0 1.6 1.6 1.4 1.2 1.2 1.3 0.6 0.8 yeast The level of expressed mRNA in the absence of chemical substance genes (11) (12) (13) (14) (15) (16) (17) (18) Intensity YBR008C 9.4 0.8 2.0 4.1 0.8 3.1 2.0 1.2 0.37 YBR296C 1.5 1.6 2.0 2.3 1.7 0.3 3.8 4.0 0.54 YDR406W 1.4 3.9 7.7 0.5 0.8 5.5 2.7 5.6 0.53 YOR153W 1.0 4.0 11.8 0.3 3.6 1.6 2.5 3.1 1.91 YGR281W 0.7 2.4 12.9 0.9 2.1 1.1 2.8 3.1 1.04 YHL047C 1.0 2.6 3.8 0.5 1.1 2.3 1.2 1.2 0.74 YBR294W 1.2 1.0 3.1 1.3 1.0 0.9 1.0 0.9 0.18 YGL006W 0.8 0.9 4.5 0.9 1.1 1.7 2.4 4.1 1.37 YGR197C 1.1 1.2 2.4 1.5 1.0 1.5 1.7 1.9 0.37 YJL034W 1.3 1.6 6.1 0.6 7.9 0.6 1.1 1.0 4.58 YNL055C 1.9 1.7 2.4 0.9 1.1 2.6 1.2 1.7 4.10 YBR052C 1.7 1.3 2.1 1.5 0.7 3.1 1.8 3.1 2.77 YBR207W 1.1 0.9 2.2 0.9 1.4 1.4 1.2 1.4 1.39 YBR293W 1.1 1.0 3.0 1.4 3.1 1.6 1.0 0.9 0.94 YDL198C 2.5 1.2 2.0 1.7 1.2 1.4 1.5 1.1 1.19 YDL245C 1.5 1.0 2.0 1.2 1.8 1.5 1.0 1.1 0.28 YDR497C 0.7 0.9 2.7 0.6 10.1 1.6 1.8 1.45 YER053C 2.4 .1.7 4.1 1.3 1.1 2.8 1.2 2.3 1.83 YFL041W 0.9 1.1 1.8 1.0 0.9 1.4 1.1 0.9 0.89 YGR055W 1.5 0.9 1.9 1.2 2.1 0.6 0.7 0.7 1.42 YJL219W 2.3 1.1 4.0 1.1 2.6 1.4 1.6 1.2 0.91 YJR106W 1.6 0.9 3.5 0.9 1.2 1.9 1.2 1.3 0.29 YKL146W 0.9 1.1 2.7 1.0 1.5 1.3 1.0 0.9 0.42 YLL028W 0.7 1.3 4.1 0.7 3.1 0.6 1.2 1.2 1.02 YLR348C 1.3 0.9 1.9 1.0 2.4 1.1 1.1 1.0 0.64 YOL119C 3.4 0.9 1.6 2.4 4.7 2.8 1.4 1.0 0.37 YOL163W 1.6 1.0 2.4 1.2 1.0 1.4 0.8 0.8 0.30 YOR035C 1.0 1.1 2.5 0.9 3.8 1.8 1.6 2.1 0.52 YOR130C 0.6 0.9 2.1 1.3 1.0 0.8 1.5 1.1 0.51 YOR273C 1.5 0.8 2.6 0.5 0.8 0.6 3.2 3.1 1.20 YOR332W 1.5 1.0 2.2 1.1 1.2 1.2 1.3 1.7 3.58 YCR098C 1.3 1.3 1.4 1.1 11.0 0.8 1.7 1.6 0.22 YGR138C 0.7 0.6 0.6 0.9 4.5 0.7 0.7 0.7 1.24 YBR295W 1.1 0.9 1.8 1.1 4.8 1.4 1.3 1.2 0.27 YGL255W 0.5 0.7 0.2 1.0 2.6 0.5 0.6 0.5 1.36 YHL035C 0.9 1.4 1.1 0.8 3.1 2.4 1.1 1.2 0.77 YIL022W 1.0 0.9 1.2 0.6 2.9 1.1 0.8 0.7 0.52 YLR378C 1.0 1.2 1.6 0.4 5.9 0.4 0.9 0.7 1.23 YCL038C 2.0 1.3 1.9 1.3 2.0 1.8 1.4 1.5 1.04 YFL054C 1.7 1.2 2.3 0.9 1.4 1.3 1.7 1.4 1.06 YHL040C 1.7 2.0 2.0 1.1 3.4 1.0 1.4 1.0 0.69 YKR039W 1.9 1.5 1.3 1.2 1.7 1.9 0.9 1.1 0.40 YPL271W 1.7 0.8 1.2 1.3 0.8 1.4 1.2 1.3 1.34 YBR068C 0.8 0.8 2.2 1.8 1.6 5.5 1.1 1.3 1.99 YCR037C 0.8 0.7 1.3 0.8 1.0 1.1 1.4 0.9 0.74 YDL128W 1.2 0.9 1.6 0.7 1.1 1.0 0.9 1.0 2.80 YDR270W 1.0 1.0 1.8 1.0 1.4 1.1 0.9 0.7 0.38 YEL065W 0.6 1.7 0.8 0.4 2.2 2.6 0.7 0.6 2.10 YGL008C 0.7 2.4 1.9 1.2 1.0 2.1 1.1 1.0 4.08 YGL104C 1.8 1.1 2.0 1.0 0.9 1.7 1.3 1.3 0.58 YGL167C 0.8 1.1 1.5 0.8 1.3 1.3 1.4 1.4 1.41 YGR065C 1.1 0.5 0.8 1.3 1.2 1.1 0.7 0.7 0.68 YHR092C 1.5 1.0 0.5 1.6 0.2 1.2 0.9 1.3 6.09 YIL088C 1.8 0.9 1.5 1.2 1.2 1.8 1.2 1.4 1.89 YNL259C 1.6 0.7 1.1 1.4 0.7 1.7 2.6 2.4 1.22 YOR270C 1.5 0.7 1.3 0.7 1.1 0.8 0.9 0.9 3.49 YPL265W 1.8 0.9 1.1 1.1 1.2 2.0 0.5 0.4 1.42 YPR124W 2.0 0.8 0.6 0.4 1.1 2.4 1.0 1.3 2.57 YER119C 2.2 0.7 1.6 1.0 2.3 0.8 1.0 0.9 0.32 YFL055W 2.7 0.9 1.3 1.5 0.7 1.4 1.4 1.0 0.23 YLL055W 3.6 0.7 1.5 1.3 0.7 2.8 1.1 1.3 0.47 YHL036W 2.3 1.2 1.5 1.2 0.9 1.1 1.0 1.0 0.60 YHR048W 2.0 0.9 1.1 1.7 0.9 1.4 0.7 0.9 0.26 YKL221W 1.9 0.7 1.6 1.4 1.1 1.3 0.8 0.9 0.27 YLR092W 3.1 1.0 1.8 1.4 0.9 1.2 1.0 1.1 0.24 YML116W 4.3 0.5 0.8 2.0 1.9 1.0 1.0 1.0 0.94 YBR291C 1.1 0.9 1.0 1.7 0.5 1.5 0.9 1.3 1.19 YCL069W 1.0 0.9 0.8 1.3 1.4 0.9 1.0 1.0 0.25 YJR095W 0.6 0.7 0.8 1.3 0.8 0.8 1.3 0.9 0.23 YKL188C 1.1 1.2 1.2 2.1 1.4 2.7 1.1 1.5 0.27 YKL217W 1.6 0.8 1.2 1.2 2.2 3.0 1.7 3.3 0.29 YKR105C 0.0 0.8 2.5 1.2 1.5 0.7 0.8 1.0 0.26 YOL158C 0.7 0.9 1.4 1.0 0.9 1.2 1.4 1.7 1.30 YPL224C 0.8 1.1 1.3 1.4 1.0 2.5 1.3 1.9 0.64 YPR201W 2.2 0.7 1.1 1.8 0.8 0.9 0.8 0.9 0.29 YAL067C 1.2 1.0 1.1 1.3 2.4 1.6 1.0 1.0 0.33 YDL149W 1.2 0.7 1.5 1.2 1.8 1.4 0.8 1.0 0.33 YJL094C 1.1 1.2 2.6 1.0 1.0 1.8 2.1 2.0 0.84 YLL061W 1.7 0.7 0.9 1.3 1.4 1.0 0.6 0.7 0.33 YPL274W 2.0 0.5 0.6 0.9 1.5 1.1 0.7 0.6 0.41 YBR241C 1.4 1.4 1.4 0.9 1.6 0.7 1.0 1.2 1.25 YDL206W 0.6 1.0 1.3 1.0 1.1 3.1 1.0 1.1 0.35 YDR040C 0.8 0.9 1.8 0.9 0.8 1.4 1.4 1.6 1.25 YFR045W 1.4 1.0 1.1 1.0 1.1 0.6 0.9 0.8 0.84 YIL170W 1.7 0.7 1.9 1.1 2.3 1.8 1.6 1.5 0.48 YKL192C 1.1 1.2 1.7 1.5 1.2 2.1 1.0 0.8 1.57 YKL209C 0.8 0.9 1.4 1.1 1.0 1.1 1.1 1.0 0.30 YKR106W 1.8 0.8 1.4 1.7 2.8 0.9 0.8 0.16 YMR056C 1.6 0.9 0.9 1.1 0.7 2.4 1.0 1.1 0.72 YPL147W 1.3 0.9 1.5 1.0 2.4 2.5 1.5 3.6 0.33 YIL166C 1.8 0.9 1.5 1.1 1.3 0.7 1.2 0.9 0.26 YMR058W 0.8 0.8 0.4 0.3 0.5 0.4 0.6 0.5 1.66 YNL142W 0.9 1.2 0.9 0.8 0.3 1.0 1.0 0.9 0.44 YDL210W 0.6 0.8 1.2 1.1 1.9 0.9 1.1 0.9 0.20 YCL025C 1.0 1.1 0.5 0.7 0.8 0.6 0.6 0.6 1.98 YJL212C 0.9 0.4 1.0 0.8 0.3 0.5 0.6 0.5 0.59 YBR132C 1.9 1.0 1.4 1.1 1.5 1.3 1.1 1.3 0.43 YBL030C 1.1 0.9 0.5 0.8 1.8 1.0 1.0 1.1 3.12 YCR024C-A 1.5 1.0 0.5 0.8 1.3 1.5 0.9 1.4 4.02 YDR342C 2.9 1.0 0.6 0.9 0.5 2.4 1.0 2.2 5.23 YDR343C 2.3 1.0 0.8 0.8 0.5 2.8 1.1 2.3 5.81 YEL027W 0.9 0.9 0.7 1.4 1.5 1.6 1.0 1.4 4.75 YHR094C 0.6 0.9 0.7 0.6 2.7 0.9 1.4 1.4 4.82 YHR175W 1.1 1.4 1.2 0.7 1.3 2.3 1.3 1.2 1.01 YIL056W 0.7 1.0 1.5 1.0 0.5 0.9 1.5 1.2 0.71 YMR203W 2.3 0.7 1.1 0.7 1.2 0.9 0.8 0.7 1.62 YBL099W 2.1 1.0 0.9 0.6 1.0 0.9 0.7 1.2 3.49 YBR127C 1.1 0.9 0.9 0.6 1.3 1.4 0.8 1.0 4.59 YDR038C 0.9 0.7 2.0 0.8 0.8 1.4 1.3 1.5 1.32 YDR039C 0.9 0.8 1.8 0.9 1.2 1.4 1.1 1.6 1.39 YDR298C 1.2 1.1 1.2 1.5 0.8 2.0 1.1 1.6 2.69 YDR345C 1.5 1.4 1.2 0.8 0.8 1.0 1.3 1.8 5.65 YEL063C 0.8 1.1 1.1 0.8 1.3 1.0 0.7 0.7 1.12 YFL011W 2.1 0.9 0.8 0.8 1.7 1.2 0.8 1.0 1.25 YGR082W 1.3 0.8 0.5 0.9 1.2 1.3 0.9 0.8 1.47 YGR191W 1.6 0.7 1.0 0.7 1.5 0.7 0.8 0.8 1.58 YGR260W 1.3 0.6 0.5 0.7 1.8 1.0 0.9 0.9 1.71 YHR026W 1.4 0.7 0.7 1.3 2.4 1.2 0.9 1.1 3.40 YJR077C 1.6 1.0 0.9 0.7 1.5 0.7 1.0 0.8 1.79 YJR121W 0.9 0.8 1.0 0.7 0.9 1.2 1.1 1.4 3.99 YLR081W 2.6 1.0 0.6 1.0 0.7 1.2 0.7 0.9 1.46 YMR011W 1.5 0.8 0.4 0.6 0.6 1.2 1.3 1.6 4.95 YOL156W 1.1 0.9 1.7 0.9 1.9 0.9 0.9 0.9 0.53 YPL036W 0.8 0.5 0.3 0.6 1.0 0.7 0.4 0.5 3.66 YGR096W 0.8 0.8 1.1 1.2 0.9 0.8 0.8 1.0 0.49 YIL006W 1.0 0.9 0.8 1.0 1.5 1.7 0.8 0.9 0.28 YKL016C 1.3 1.0 1.3 1.6 0.7 1.8 1.0 1.7 2.08 YKR067W 1.3 1.0 1.3 1.3 1.3 2.0 0.8 1.0 0.58 YMR162C 1.7 0.7 0.9 1.0 1.0 0.8 0.8 1.1 0.32 YOR348C 1.1 0.7 1.1 1.2 1.6 1.7 0.9 0.9 0.18 YPR192W 0.7 0.5 1.1 0.7 1.7 2.6 1.6 0.9 0.28 YPR194C 0.7 0.7 1.0 1.0 0.4 0.8 1.0 0.9 0.27 YDR086C 1.1 0.7 0.7 1.5 2.1 1.3 1.4 1.9 2.60 YGR224W 0.8 0.6 0.8 0.9 1.1 1.0 2.8 1.3 0.27 YDR387C 2.0 0.9 1.3 0.9 1.4 2.7 1.2 1.1 0.86 YFL050C 1.2 0.9 1.2 1.0 1.4 2.3 0.8 1.0 0.36 YBR298C 1.5 1.1 0.8 0.9 0.2 2.1 0.9 0.8 0.88 YLR295C 1.3 0.5 0.8 1.2 0.5 2.4 0.9 1.5 1.07 YNR072W 1.4 1.0 1.5 1.0 1.8 2.1 1.3 1.0 0.26 YOR316C 2.4 1.1 1.6 1.0 1.5 2.2 0.8 1.0 0.93 YOR328W 1.1 1.8 0.8 3.3 2.1 0.19 YPL134C 1.7 0.8 1.0 1.4 1.1 3.3 1.3 1.3 0.70 -
TABLE 6 Stress protein genes yeast The level of expressed mRNA in the presence of chemical substance/ genes (1) (2) (3) (4) (5) (6) (7) (8) (9) (10) YBR072W 18.5 17.4 18.4 10.5 1.2 32.2 6.6 2.1 29.4 43.4 YFL014W 3.4 5.1 5.7 11.0 1.0 9.3 5.5 3.4 13.1 5.8 YLL060C 12.5 4.2 2.3 2.6 0.9 1.4 2.0 5.8 13.0 23.2 YAL005C 0.6 1.6 7.0 0.9 1.2 1.6 1.2 0.9 3.9 1.8 YBL075C 1.3 4.3 3.1 1.6 1.1 0.8 1.3 0.8 60.3 6.7 YBR169C 1.0 2.1 3.9 1.9 0.8 4.9 2.5 0.9 7.0 4.3 YCL035C 2.0 2.3 1.5 1.7 1.5 5.1 2.7 1.4 1.9 2.3 YCR060W 0.7 0.9 0.8 3.3 2.4 1.2 0.7 1.1 YDR155C 1.1 1.5 3.2 1.8 0.8 1.5 1.2 1.4 1.3 1.3 YDR258C 1.6 2.3 2.8 1.4 1.3 2.4 3.9 1.9 4.9 13.3 YER103W 0.7 2.1 5.2 2.1 1.1 1.7 1.0 0.9 20.3 9.0 YKL210W 0.5 1.7 2.7 0.7 0.8 1.4 1.0 0.9 3.5 2.9 YLL024C 0.5 1.6 5.3 0.8 0.7 1.0 1.1 0.7 2.8 2.4 YLL026W 1.8 2.9 7.7 1.7 0.9 1.9 2.9 1.4 11.4 6.6 YNL160W 2.1 3.7 10.6 2.0 1.3 5.8 2.4 1.2 3.5 2.7 YNL241C 1.3 2.5 4.3 1.0 0.8 0.9 3.2 0.9 3.4 7.4 YOR027W 0.7 2.4 4.4 0.8 1.0 1.6 1.3 0.9 3.5 4.0 YPL240C 0.7 1.4 2.4 0.9 1.3 1.2 1.4 1.2 3.5 2.6 YDR293C 0.9 0.9 1.2 1.4 0.6 0.9 0.9 0.6 1.2 1.2 YDR436W 0.9 0.9 1.1 1.4 0.7 1.1 1.2 0.9 3.5 1.1 YDR519W 1.3 3.2 1.7 1.6 0.7 1.3 1.9 1.4 0.5 1.2 YEL030W 0.7 0.9 1.9 1.1 0.4 0.6 0.9 0.7 2.3 2.5 YER125W 0.6 1.1 1.5 0.9 1.4 0.7 0.8 0.7 0.6 1.2 YFL016C 0.8 1.0 1.6 0.9 1.3 1.3 1.4 0.7 6.4 2.9 YFR052W 1.1 1.6 1.3 1.5 1.4 3.2 2.2 1.5 3.7 3.0 YHR057C 1.1 1.2 0.7 0.9 1.3 1.3 1.3 1.0 2.6 1.2 YIR037W 1.4 2.2 2.0 2.3 0.6 2.7 1.8 1.3 6.2 3.8 YIR038C 1.3 3.5 4.6 2.0 0.7 2.5 2.0 1.3 4.6 4.5 YJR045C 0.5 1.9 3.9 0.5 1.2 1.0 0.8 3.2 3.0 YLL039C 1.1 1.0 1.7 1.2 0.9 1.5 1.1 1.1 3.4 1.5 YLR259C 0.7 1.0 3.1 1.6 1.1 0.9 1.8 0.8 1.8 2.6 YML070W 0.9 1.7 2.5 1.9 1.4 2.2 3.1 1.3 4.5 3.9 YPL106C 0.6 1.7 2.4 1.1 1.2 1.6 1.1 1.2 4.9 1.8 YPR026W 0.9 1.2 5.0 1.3 0.8 1.3 1.0 0.9 3.1 YDR077W 1.2 1.0 3.5 2.1 0.8 1.0 0.7 0.8 0.7 0.7 YKL163W 1.1 1.4 3.4 1.9 0.6 1.1 0.9 0.8 0.7 1.6 YLR109W 0.8 2.9 6.0 0.9 1.3 2.1 2.6 0.9 2.4 2.7 YOR208W 1.3 1.0 1.2 2.9 1.4 1.8 1.1 1.0 1.5 2.0 YDR098C 0.8 1.4 1.0 0.8 1.5 1.1 .1.5 1.2 3.7 1.5 YHR030C 2.1 0.8 0.6 2.9 1.8 0.9 1.8 1.5 0.6 2.5 YJL159W 1.0 1.3 2.8 1.1 1.0 1.8 0.9 0.8 0.5 1.2 YMR173W 1.5 3.6 3.0 0.9 1.1 5.0 2.4 2.3 2.7 8.2 YCR021C 5.2 1.4 4.2 8.6 0.9 2.2 0.9 0.8 2.2 1.0 YDL022W 0.9 2.6 6.9 1.5 0.7 2.1 1.5 0.8 1.2 1.8 YDR033W 1.1 1.3 4.6 1.5 1.1 6.7 0.8 1.0 0.3 1.0 YFL020C 1.0 1.1 1.9 1.2 1.1 2.0 1.4 0.7 1.3 1.4 YGL073W 1.0 2.1 0.9 1.0 1.7 1.9 1.3 0.8 1.9 2.4 YIL033C 0.8 1.3 3.3 1.3 0.7 2.0 1.1 0.7 2.4 1.3 YMR021C 1.0 0.7 0.9 1.1 1.6 2.2 2.5 1.3 0.6 1.3 YBR126C 0.8 1.9 5.6 1.2 0.7 2.9 2.3 0.6 1.7 YBR067C 1.6 2.5 2.8 0.9 1.1 1.1 1.1 1.1 1.7 1.0 YDR513W 2.2 2.5 2.3 2.6 0.9 2.1 1.6 1.6 4.6 3.1 YGR088W 1.3 1.2 7.7 2.4 1.0 1.3 0.8 0.8 1.5 3.2 YHR104W 1.0 4.1 15.7 1.9 1.1 1.2 1.5 1.1 4.8 2.3 YKL161C 4.2 0.8 0.9 2.2 1.4 2.0 2.0 1.9 1.4 1.7 YPL223C 4.8 20.0 1.2 5.1 0.9 1.5 1.1 1.2 29.4 16.5 YBR054W 1.9 1.8 5.4 1.7 0.8 1.1 0.6 2.1 0.4 1.2 YAL015C 1.2 1.1 1.7 1.9 1.1 0.7 1.2 1.1 4.0 2.7 YDL025C 1.7 5.0 3.5 1.5 0.6 0.6 1.0 1.1 3.6 4.5 YML007W 0.9 0.8 0.9 1.3 1.0 0.5 1.1 1.9 2.1 2.5 YER042W 3.0 2.2 3.1 1.0 1.1 1.6 1.1 1.7 6.8 2.1 YOL064C 1.4 2.1 1.1 0.6 0.9 1.4 1.2 1.0 8.7 2.7 YGL181W 0.9 0.9 1.2 1.1 1.1 1.9 1.3 1.2 2.7 2.3 YJL128C 0.8 1.4 0.4 0.8 1.2 1.3 1.8 0.9 2.0 1.7 YJL165C 1.0 0.8 1.3 1.6 1.1 0.5 0.8 0.7 2.8 1.0 YJR090C 0.8 1.0 0.6 0.8 1.2 1.2 0.8 0.8 1.9 1.2 YMR186W 0.6 1.4 2.0 0.9 1.3 1.3 1.2 0.8 2.6 1.3 YNL064C 0.9 1.8 1.8 1.1 0.9 0.8 0.6 1.4 2.4 1.8 YOR008C 0.7 0.8 1.4 1.1 1.4 1.1 0.8 0.8 1.9 1.0 YPL194W 0.9 1.4 0.4 1.1 1.3 1.1 1.5 1.3 9.6 3.1 YBL093C 1.0 2.0 0.4 1.4 1.0 0.8 1.3 1.6 0.7 1.1 YKR053C 0.9 2.0 1.0 1.2 1.0 1.1 1.7 0.9 0.8 1.8 YJL158C 0.9 0.6 2.8 1.5 1.4 0.5 0.4 0.7 0.2 0.5 YER057C 1.2 2.0 3.0 1.8 0.8 1.6 1.4 1.0 0.6 1.4 YHL046C 1.1 1.7 2.1 1.3 0.9 0.8 1.3 1.0 1.0 2.1 YIL011W 0.7 0.5 3.9 0.6 1.1 0.7 0.6 0.7 0.0 0.5 YKL164C 0.6 1.1 2.5 0.9 1.1 1.4 0.8 0.8 0.4 0.7 YNR076W 1.3 1.3 2.5 1.0 1.2 1.2 1.2 1.0 1.3 2.5 YOL161C 1.2 1.1 2.4 1.4 0.9 1.0 0.9 0.8 0.7 2.0 YOR009W 0.9 0.8 3.2 0.7 0.8 0.9 0.6 0.7 0.4 0.5 YOR010C 0.7 0.7 3.2 0.6 1.2 0.5 0.4 0.5 0.6 0.7 YPL059W 1.2 0.9 2.6 1.3 1.2 1.3 0.7 1.4 2.0 1.3 YBR044C 0.8 1.4 0.7 1.9 1.4 1.0 1.5 1.1 0.8 1.2 YEL039C 1.1 0.7 1.3 5.1 0.9 1.5 0.6 1.1 1.2 1.2 YGL115W 0.9 0.6 1.2 2.0 1.2 1.2 1.4 1.0 1.2 1.2 YLR006C 0.7 0.7 0.9 6.2 1.6 0.9 1.1 0.9 1.1 1.1 YPR005C 1.3 0.8 1.5 3.8 1.0 0.8 1.2 1.2 2.8 2.0 YHL028W 0.7 0.8 1.4 0.5 1.1 1.8 2.1 0.4 0.2 0.4 YCR083W 1.1 2.8 1.5 1.8 1.6 2.4 1.8 1.5 1.8 1.8 YPL140C 0.9 1.3 0.9 1.0 0.8 0.3 1.4 1.1 0.9 0.9 yeast The level of expressed mRNA in the absence of chemical substance genes (11) (12) (13) (14) (15) (16) (17) (18) Intensity YBR072W 6.3 16.3 38.5 5.8 4.9 23.1 1.8 2.2 0.59 YFL014W 5.0 4.3 15.2 7.3 6.3 14.2 1.5 8.8 2.14 YLL060C 14.1 1.1 1.8 10.6 1.5 3.6 1.9 2.3 0.57 YAL005C 1.0 1.2 5.0 0.4 1.6 0.7 0.8 0.5 5.23 YBL075C 1.6 1.1 8.0 1.1 2.6 2.2 1.2 0.7 1.17 YBR169C 2.2 1.7 7.2 1.1 1.6 2.4 1.3 1.6 1.10 YCL035C 2.1 1.5 2.8 2.5 1.9 5.5 2.6 4.2 1.74 YCR060W 1.2 1.7 8.6 1.7 3.3 1.2 1.7 1.04 YDR155C 3.8 1.4 3.3 1.0 2.5 1.6 1.2 2.5 4.99 YDR258C 1.7 1.8 5.2 1.5 0.6 1.0 1.3 1.3 0.87 YER103W 1.8 1.9 9.0 0.9 3.2 1.2 1.4 0.6 2.10 YKL210W 1.4 1.3 2.9 0.8 1.0 0.9 0.7 1.1 2.29 YLL024C 1.6 1.0 4.8 0.4 1.3 0.5 0.5 0.6 5.12 YLL026W 1.7 1.9 8.1 0.8 0.9 1.6 1.7 2.5 2.56 YNL160W 5.4 1.4 6.0 1.3 0.7 4.0 1.0 1.0 1.77 YNL241C 3.0 2.0 4.9 1.1 7.0 2.8 1.0 1.0 0.68 YOR027W 1.3 1.3 5.1 0.8 1.4 0.6 0.9 0.8 1.52 YPL240C 1.0 0.8 2.9 0.7 1.2 0.7 0.8 1.0 4.83 YDR293C 1.1 0.9 2.3 0.8 1.7 1.6 1.4 1.3 1.12 YDR436W 2.0 0.9 2.7 1.2 0.8 1.4 0.9 1.2 0.53 YDR519W 1.2 1.7 2.5 1.3 2.0 1.5 1.8 2.4 2.01 YEL030W 1.7 0.9 2.7 0.7 0.8 0.8 0.9 0.6 1.28 YER125W 1.0 0.7 1.9 0.7 0.8 1.0 1.0 1.0 1.48 YFL016C 1.2 1.0 2.8 0.8 0.8 0.6 1.2 0.9 1.25 YFR052W 0.9 1.8 3.8 3.3 1.4 2.7 1.2 1.9 1.62 YHR057C 1.6 1.1 1.9 1.9 1.2 2.2 1.6 1.3 1.07 YIR037W 3.0 1.3 2.4 2.3 1.0 4.0 1.7 2.9 1.97 YIR038C 3.4 1.1 2.5 2.5 1.2 6.0 2.8 2.0 1.11 YJR045C 1.4 1.0 2.3 0.5 2.3 0.8 0.7 0.9 3.78 YLL039C 1.1 1.0 2.2 1.4 3.0 1.1 1.6 2.1 3.60 YLR259C 3.0 0.7 2.5 0.8 2.1 1.3 0.8 1.0 2.09 YML070W 1.5 1.3 3.3 1.3 0.9 2.6 1.2 1.3 1.03 YPL106C 1.3 1.1 3.1 0.9 1.1 0.5 0.5 0.5 3.34 YPR026W 1.6 1.2 2.3 1.5 3.1 2.5 0.9 1.3 0.26 YDR077W 6.8 0.8 1.0 0.3 6.1 1.0 1.4 1.1 4.77 YKL163W 1.3 0.9 1.5 0.5 16.8 3.0 0.8 1.0 2.01 YLR109W 1.5 1.6 3.2 2.3 3.9 1.8 1.1 1.2 3.86 YOR208W 1.2 1.2 1.5 1.3 4.4 1.9 1.6 1.6 0.56 YDR098C 1.4 1.3 1.2 1.5 2.2 0.8 1.0 1.2 1.59 YHR030C 1.5 0.7 1.0 1.1 3.4 1.4 2.0 1.8 1.05 YJL159W 1.2 1.0 1.7 0.6 5.3 1.0 1.4 0.9 2.45 YMR173W 3.2 1.4 2.0 2.3 2.5 1.2 1.9 1.8 1.37 YCR021C 0.6 0.5 0.9 1.6 0.5 0.6 0.7 0.8 1.36 YDL022W 2.8 1.2 1.5 0.8 0.9 1.1 1.0 1.4 1.79 YDR033W 0.7 1.0 0.7 1.0 0.8 1.0 0.7 1.0 5.78 YFL020C 1.2 1.3 1.4 1.0 1.4 0.9 1.5 0.9 0.70 YGL073W 0.8 0.8 1.5 1.2 0.9 1.1 2.5 1.2 0.66 YIL033C 1.8 1.1 2.5 0.7 1.0 2.0 1.0 1.2 1.18 YMR021C 0.9 0.8 1.4 1.3 1.0 2.0 3.3 3.4 1.14 YBR126C 1.1 1.3 2.1 0.7 1.0 1.7 1.5 1.3 1.96 YBR067C 3.1 1.0 0.9 0.7 3.3 2.5 0.5 0.4 1.76 YDR513W 2.0 0.9 1.8 2.0 1.3 3.8 1.3 3.2 3.10 YGR088W 3.9 1.1 1.2 1.3 0.7 5.6 0.9 2.0 0.75 YHR104W 2.6 1.0 1.2 1.5 1.6 1.3 1.9 1.9 1.57 YKL161C 3.1 0.9 1.3 1.4 1.3 1.1 1.4 1.9 0.45 YPL223C 1.8 0.9 2.3 2.5 1.5 19.0 1.0 1.3 0.31 YBR054W 1.8 0.7 1.5 1.0 0.6 0.4 0.7 0.7 3.02 YAL015C 1.4 1.0 1.2 1.6 0.7 2.0 1.1 1.2 0.61 YDL025C 1.5 0.9 1.2 1.7 1.0 1.7 1.0 1.4 0.56 YML007W 1.3 1.1 1.7 1.2 1.0 1.4 1.0 1.4 1.54 YER042W 1.8 1.1 1.4 5.2 1.0 1.9 0.7 1.1 1.80 YOL064C 1.0 0.9 2.0 0.9 1.0 1.7 1.2 1.3 1.32 YGL181W 1.2 1.0 2.8 1.0 1.5 1.3 1.0 1.3 0.98 YJL128C 0.6 1.0 1.7 0.8 1.2 0.9 1.0 1.0 0.42 YJL165C 1.7 0.9 1.5 0.9 1.0 1.5 1.3 1.8 0.87 YJR090C 0.4 0.8 2.2 1.0 1.6 0.8 1.1 1.0 0.60 YMR186W 1.1 1.0 2.4 0.6 1.3 0.6 0.7 1.1 6.64 YNL064C 0.9 0.8 1.1 0.8 0.7 0.3 0.7 0.7 3.79 YOR008C 1.0 0.7 0.9 0.9 0.9 1.2 0.8 1.3 1.75 YPL194W 0.9 0.9 1.4 1.1 1.4 0.9 1.0 0.8 0.22 YBL093C 1.3 1.1 2.1 1.0 0.5 0.9 1.4 1.3 1.47 YKR053C 0.5 0.7 0.7 1.3 0.3 0.9 2.8 2.4 0.35 YJL158C 1.9 1.1 0.4 0.5 1.7 0.6 1.4 1.4 3.48 YER057C 1.8 1.5 1.0 1.4 1.7 2.8 1.1 1.8 2.03 YHL046C 0.4 1.1 1.4 1.4 1.0 1.4 0.9 0.9 0.55 YIL011W 2.5 0.6 0.5 0.5 0.9 1.0 0.8 0.8 0.57 YKL164C 1.0 0.8 0.9 0.3 1.2 1.1 0.8 0.8 2.75 YNR076W 1.4 0.7 0.9 0.8 1.1 0.8 1.5 0.8 0.42 YOL161C 1.5 1.3 1.2 0.9 1.1 1.6 1.1 1.0 0.89 YOR009W 1.4 0.4 0.4 0.7 0.6 0.8 0.9 0.8 0.36 YOR010C 1.2 0.5 0.5 0.4 0.6 1.1 1.4 0.6 0.61 YPL059W 1.6 0.8 0.7 1.3 1.0 2.1 1.8 1.3 1.35 YBR044C 1.1 0.8 1.2 0.9 0.9 1.4 0.9 1.3 0.57 YEL039C 1.7 0.6 0.5 1.4 0.4 3.5 0.7 1.1 1.59 YGL115W 1.0 0.9 0.7 1.2 0.7 1.7 0.8 1.2 2.46 YLR006C 1.5 0.7 0.8 1.0 0.9 0.8 1.6 1.0 0.40 YPR005C 0.4 0.6 0.7 1.3 2.7 0.8 1.0 1.1 0.24 YHL028W 0.7 1.5 2.1 1.3 0.6 2.6 1.6 2.5 0.62 YCR083W 1.8 1.1 1.8 2.4 1.0 3.1 1.3 1.3 0.98 YPL140C 0.8 0.8 0.9 1.1 0.7 1.8 0.9 1.4 0.46 -
TABLE 7 Metabolism protein genes yeast The level of expressed mRNA in the presence of chemical substance/ genes (1) (2) (3) (4) (5) (6) (7) (8) (9) (10) YCR107W 12.0 2.6 1.8 1.6 0.7 1.5 1.5 15.6 196.6 34.0 YDL243C 14.4 2.7 2.4 1.0 1.1 2.2 1.6 11.8 64.2 29.6 YFL014W 3.4 7.2 5.7 11.0 1.0 9.3 5.5 3.4 13.1 5.8 YFL056C 19.0 2.3 2.3 1.5 0.9 0.6 1.4 18.5 162.3 31.3 YFL057C 20.9 5.8 1.5 1.8 0.9 1.2 1.8 18.0 51.8 46.1 YJR155W 10.6 3.7 1.4 2.5 0.7 1.4 1.7 10.6 38.2 18.8 YNL331C 8.6 3.6 1.3 1.0 1.6 1.8 1.9 13.1 42.6 36.3 YNL332W 1.1 1.5 1.1 2.0 1.6 1.1 2.1 1.5 3.3 2.1 YOL165C 10.1 4.5 1.8 0.9 0.9 1.7 1.4 17.8 46.9 23.3 YPR167C 5.3 5.8 1.9 0.8 1.4 2.6 1.2 5.5 76.6 9.0 YBR256C 3.0 1.4 0.6 1.3 1.6 2.0 2.1 2.3 18.1 6.8 YBR296C 7.0 11.2 2.2 2.5 1.4 1.4 0.2 1.1 0.4 1.8 YDL021W 4.8 1.7 2.4 3.7 1.7 6.5 5.9 2.7 2.5 7.4 YFL061W 1.5 1.4 2.1 3.0 1.0 0.5 1.2 1.2 3.2 9.9 YGR043C 2.5 4.7 3.2 7.9 0.9 16.3 6.5 2.6 10.9 8.4 YHR112C 1.8 3.1 0.7 1.4 1.3 2.9 3.4 1.7 10.5 4.4 YIR030C 1.4 1.0 0.9 1.3 0.9 0.5 1.2 1.4 5.4 2.1 YJR010W 9.1 7.3 4.9 0.8 1.1 2.5 1.4 3.1 30.0 11.1 YKL001C 6.8 21.4 5.6 1.8 0.8 0.9 1.1 3.4 10.3 3.4 YKR097W 1.3 2.4 1.3 3.3 1.1 1.7 3.7 2.5 1.9 3.3 YLR303W 7.3 9.8 12.1 1.1 1.1 3.0 3.6 5.3 18.6 5.6 YNL274C 1.4 18.7 2.6 1.9 0.7 4.2 2.0 2.3 6.3 5.3 YOL151W 6.7 3.8 9.1 1.3 1.3 8.4 4.4 6.7 22.8 17.0 YOR226C 1.3 2.2 1.7 1.1 1.3 1.2 1.2 1.2 1.3 5.9 YJL153C 1.3 1.7 1.7 17.6 0.7 0.8 2.3 1.3 3.9 2.5 YOR153W 1.6 0.9 5.1 1.1 1.0 7.4 2.6 0.5 3.2 1.2 YPL088W 3.3 1.3 0.6 2.5 1.5 7.1 3.7 1.9 0.6 2.8 YDL124W 2.1 8.5 5.7 1.7 0.7 3.4 2.9 2.1 3.3 5.3 YDL174C 0.9 1.8 0.9 1.3 0.5 1.7 3.6 0.8 0.5 1.7 YGL156W 1.3 2.5 1.8 2.2 1.4 2.1 2.1 1.4 5.6 2.4 YGR157W 1.0 0.9 5.2 0.8 1.2 1.0 0.8 0.7 3.3 2.0 YHR043C 1.3 1.8 1.2 1.7 0.9 2.2 2.9 3.0 1.2 1.0 YHR044C 1.3 1.3 1.7 1.5 1.2 3.3 2.6 2.0 1.1 1.1 YJR073C 1.1 2.4 2.7 2.7 0.6 2.2 2.9 1.0 6.8 2.8 YOR303W 1.1 2.2 0.5 1.0 1.2 1.8 1.2 1.6 0.9 5.2 YBR294W 6.3 12.0 0.9 2.6 1.4 1.2 1.1 1.0 5.2 5.2 YCL043C 0.6 3.7 2.5 0.7 0.9 1.3 1.0 0.8 1.6 1.2 YCL050C 1.0 1.1 1.9 0.7 1.4 1.2 1.2 1.2 3.0 2.9 YCR012W 1.1 1.5 5.1 1.2 1.1 2.5 1.4 0.8 1.4 1.5 YDR158W 1.1 0.5 1.8 0.8 1.3 1.0 0.8 1.2 1.1 1.7 YDR204W 0.9 2.3 3.0 1.4 1.0 2.2 2.2 1.1 5.7 3.7 YDR313C 1.2 1.2 1.2 1.4 1.3 1.4 1.5 1.2 4.7 2.6 YDR368W 2.0 2.2 2.2 1.8 1.0 3.0 2.1 1.7 3.8 3.8 YER091C 3.6 3.9 30.7 1.3 0.9 2.3 2.1 0.9 5.8 1.4 YFR053C 1.7 1.4 3.0 2.2 0.9 3.2 2.1 2.8 0.6 1.1 YGL062W 0.6 1.3 1.1 0.6 0.9 1.0 1.3 0.8 1.6 2.5 YGL157W 0.7 0.9 1.8 0.9 1.5 5.4 3.3 1.4 0.6 1.8 YGL184C 4.6 15.9 57.4 1.3 1.1 1.0 1.2 1.9 37.9 66.8 YGR032W 1.0 1.4 1.0 1.3 0.7 1.9 0.8 0.6 0.5 0.7 YGR124W 0.5 0.6 1.7 0.7 1.2 1.1 0.7 1.0 2.2 1.3 YGR192C 1.4 1.0 3.8 1.0 1.1 1.7 1.7 1.1 0.9 1.3 YGR244C 1.0 1.2 1.6 1.6 0.8 2.6 3.9 1.8 1.4 1.1 YGR254W 1.2 1.3 3.8 1.3 1.2 1.9 1.5 1.4 0.8 1.2 YHR018C 1.0 1.0 1.5 1.4 1.7 1.1 0.8 1.0 1.4 4.4 YIL160C 0.8 2.4 2.3 3.5 1.0 1.6 1.1 1.2 3.2 3.8 YIR017C 3.5 8.6 2.5 1.9 0.8 1.9 1.5 1.2 5.2 3.4 YJL052W 1.5 0.9 4.0 1.8 0.7 2.4 2.1 1.5 1.6 2.0 YJR009C 1.1 1.7 5.6 1.0 1.2 1.6 1.6 1.1 1.1 1.3 YJR130C 1.1 0.6 0.8 0.9 1.4 2.0 1.3 1.3 5.2 3.8 YJR149W 1.0 1.8 1.4 2.3 0.8 1.0 1.7 1.0 1.4 1.0 YKL218C 2.1 1.0 2.2 1.8 1.2 3.6 1.6 1.7 3.4 2.7 YLR027C 1.0 1.5 2.3 0.8 0.9 2.0 1.4 0.7 1.6 2.7 YLR133W 0.9 1.6 1.4 0.7 1.0 2.2 1.3 0.7 6.1 2.3 YLR155C 1.4 1.1 2.4 1.8 1.7 1.6 2.0 1.0 3.0 1.8 YLR158C 1.4 1.2 2.1 1.7 1.7 1.5 2.0 1.1 2.7 s YLR195C 0.8 0.9 1.0 0.8 1.0 0.8 1.1 1.0 0.6 0.7 YLR345W 1.4 1.4 1.4 1.2 1.2 1.6 1.2 1.4 4.5 4.0 YML004C 0.8 1.6 2.5 1.0 0.7 1.7 2.1 1.9 3.9 2.2 YML131W 11.2 4.3 7.7 1.9 0.7 2.0 3.0 6.1 11.1 17.7 YNL071W 0.9 0.9 1.7 1.5 0.6 1.3 1.4 0.9 1.1 1.2 YNL241C 1.3 2.5 4.3 1.0 0.8 0.9 3.2 0.9 3.4 7.4 YOR120W 1.8 5.4 2.8 3.2 1.4 3.4 2.7 2.0 3.3 3.0 YAL023C 0.4 1.5 1.0 0.7 1.0 0.6 0.8 0.6 0.3 0.4 YAL060W 1.1 1.8 3.2 2.7 1.2 4.2 3.3 0.9 0.6 2.5 YAL062W 0.8 1.5 1.4 1.1 1.0 1.2 1.1 0.8 1.4 0.7 YBR006W 1.3 1.6 2.6 1.5 1.3 3.1 3.3 1.0 4.5 2.7 YBR056W 1.4 1.7 1.4 2.3 1.4 2.3 5.5 1.4 3.0 3.3 YBR149W 1.1 2.0 2.7 1.7 1.4 2.8 3.1 1.5 1.7 1.9 YBR284W 0.9 1.5 2.8 4.8 1.3 1.9 1.0 0.9 6.5 3.2 YCL018W 1.2 2.7 2.4 1.4 0.8 2.3 2.3 1.3 2.1 4.3 YCL040W 0.9 7.1 10.1 2.0 0.5 3.5 2.9 0.7 0.9 3.0 YDL010W 1.7 0.8 0.6 0.7 1.2 1.1 1.9 1.1 2.2 1.3 YDL024C 1.6 1.5 1.2 2.2 1.0 1.7 0.9 1.7 4.2 3.4 YDL095W 0.5 1.3 1.0 0.8 0.8 1.0 0.8 0.7 1.2 0.7 YDL245C 1.0 2.4 1.6 2.2 1.3 1.1 1.2 1.2 0.4 2.8 YDL246C 1.2 1.5 1.3 1.1 1.1 1.4 2.1 2.4 4.4 3.6 YDR001C 0.8 2.2 2.6 1.0 1.1 2.2 1.5 0.9 2.2 3.0 YDR058C 1.2 2.2 0.8 2.7 0.7 1.0 1.4 1.9 2.4 1.7 YDR072C 1.3 1.3 1.7 1.2 0.9 1.5 0.9 0.7 0.6 0.7 YDR127W 0.8 0.9 1.5 0.7 1.2 0.8 0.9 0.7 0.6 1.3 YDR261C 1.2 1.2 1.9 0.7 1.3 1.4 0.8 0.9 1.7 1.0 YDR272W 1.0 4.0 0.8 1.8 0.7 2.3 1.7 2.1 2.5 1.9 YDR497C 0.7 0.5 0.6 1.3 0.7 0.6 0.5 0.6 0.4 0.8 YDR516C 1.2 1.5 7.8 2.1 1.3 1.8 3.9 1.3 1.8 5.2 YER053C 1.6 1.8 1.9 1.7 0.6 2.8 2.8 1.3 1.3 3.9 YER096W 1.1 2.3 2.0 2.0 1.3 1.2 0.9 1.0 7.5 3.5 YER178W 0.8 0.9 3.6 1.0 0.7 2.5 1.6 0.8 1.7 1.3 YFL030W 1.6 6.0 3.1 2.0 1.1 1.3 0.6 1.6 24.5 4.9 YFL031W 0.5 1.3 2.1 0.7 1.0 0.3 0.9 0.7 1.0 0.7 YFR047C 1.3 4.0 2.7 2.6 1.2 2.0 2.0 1.0 3.0 1.5 YGL248W 1.3 1.3 0.9 0.7 1.3 2.7 1.6 0.8 0.2 2.9 YGR037C 1.0 1.2 2.2 0.8 1.0 1.1 1.4 1.4 1.7 1.4 YGR055W 2.5 5.7 12.0 0.7 1.3 1.1 0.6 1.1 5.0 2.4 YGR194C 0.9 1.0 1.3 2.1 0.8 1.9 2.2 1.2 2.4 2.1 YGR256W 1.2 1.5 2.3 0.8 0.9 6.2 1.4 2.2 3.4 2.5 YHR111W 1.4 1.3 0.8 1.9 1.5 1.3 1.6 1.3 4.5 4.2 YHR174W 1.1 1.4 3.3 1.2 1.3 1.5 1.6 1.2 1.0 1.5 YHR176W 1.8 2.0 1.1 1.4 1.0 2.3 1.4 1.3 6.3 6.4 YIL045W 1.7 1.4 1.9 2.2 1.3 1.7 1.6 1.1 2.1 3.2 YIL107C 1.5 0.8 1.1 1.5 0.8 1.0 1.6 1.3 3.5 3.5 YIL155C 1.0 0.7 1.4 3.7 1.3 1.4 2.2 1.0 2.5 2.9 YIR034C 1.2 1.1 2.5 0.6 1.1 1.3 0.8 1.7 3.2 3.5 YIR036C 1.0 1.7 2.6 1.8 0.9 0.7 1.0 1.0 3.3 1.9 YJL031C 1.6 1.2 0.5 1.3 1.7 1.6 2.3 1.8 4.7 3.6 YJL068C 1.2 2.7 3.4 1.6 0.7 1.1 1.2 1.1 6.5 3.1 YJL099W 1.2 1.2 0.3 1.3 1.9 2.0 1.8 1.0 3.1 3.1 YJL172W 0.8 2.1 1.8 1.5 0.9 3.8 1.0 0.7 0.7 1.9 YJL219W 1.2 2.5 3.1 1.6 1.2 1.5 0.9 1.5 4.0 2.3 YJR137C 2.7 2.9 4.6 0.8 0.6 1.5 0.8 1.6 9.0 4.8 YKL035W 1.0 0.9 4.8 1.2 0.8 1.2 0.6 1.0 0.8 1.2 YKL091C 1.2 1.3 1.4 2.6 1.0 2.2 1.9 1.3 2.3 3.2 YKL104C 1.0 1.0 1.6 1.2 1.4 0.9 2.3 1.1 1.4 1.8 YKL152C 1.3 1.3 1.9 0.9 1.3 1.6 1.5 1.0 0.9 1.5 YKL213C 0.9 0.8 1.0 1.3 0.7 1.0 1.0 1.1 4.8 2.1 YKL215C 0.6 1.1 1.3 0.8 1.0 2.1 1.1 1.1 1.3 1.9 YLL058W 1.0 3.8 1.4 0.9 0.8 1.4 1.5 0.9 3.5 3.6 YLR299W 1.2 1.9 1.5 1.3 0.6 0.9 0.8 1.0 4.9 2.3 YLR348C 1.1 4.5 1.2 1.2 0.9 1.9 0.9 0.9 2.1 1.3 YML054C 1.5 1.8 1.3 3.4 1.3 1.8 1.2 1.5 4.1 1.8 YML070W 0.9 1.7 2.5 1.9 1.4 2.2 3.1 1.3 4.5 3.9 YML100W 0.8 2.7 10.6 1.4 0.9 2.8 2.2 0.7 1.7 1.4 YMR008C 0.7 0.9 1.4 1.0 1.1 1.7 0.9 0.5 0.3 0.6 YMR020W 1.3 1.0 0.9 1.7 1.4 1.6 2.7 1.2 2.3 2.9 YMR105C 1.9 3.0 5.0 4.2 0.9 2.8 2.8 1.1 0.6 2.9 YMR271C 1.6 1.6 1.3 2.0 1.1 4.2 3.4 1.8 8.0 4.4 YNL012W 1.3 1.3 1.8 0.8 1.3 1.7 2.0 1.8 3.3 3.2 YNL045W 0.8 1.3 2.0 1.3 1.1 2.2 1.8 0.7 1.3 1.1 YNL104C 1.1 1.3 3.0 0.9 0.8 0.8 0.6 0.9 1.1 2.0 YNL231C 1.5 0.8 0.8 0.5 2.1 1.8 2.5 1.5 2.2 1.3 YNR019W 1.0 1.3 1.6 1.2 0.8 1.3 0.8 0.7 1.8 1.9 YNR033W 0.6 0.8 0.8 1.0 1.3 1.6 1.2 1.1 3.6 4.2 YNR059W 1.1 0.9 0.2 1.4 1.4 0.8 1.6 1.3 1.8 1.4 YOL126C 1.0 0.8 1.0 1.6 0.7 1.5 1.4 0.9 0.8 2.4 YOL153C 1.0 1.2 2.1 3.9 1.2 1.9 3.3 1.0 2.5 3.2 YOR099W 0.8 1.3 2.1 1.3 1.5 0.9 1.0 0.9 0.6 0.7 YOR130C 0.8 1.7 1.4 1.0 1.8 1.6 1.3 0.8 2.0 1.7 YOR336W 0.7 1.4 0.7 1.0 1.3 1.7 1.2 0.8 1.7 1.5 YOR347C 0.9 0.9 2.1 2.2 0.7 0.9 0.9 0.8 0.5 0.9 YPL017C 1.0 2.5 0.8 1.0 1.3 1.5 1.4 1.3 3.0 6.7 YPR026W 0.9 1.2 5.0 1.3 0.8 1.3 1.0 0.9 3.1 YAL012W 1.1 6.5 10.4 0.8 0.6 1.6 0.6 0.7 4.7 3.9 YBR029C 0.7 0.2 1.8 1.0 1.4 0.8 0.4 0.7 2.0 1.1 YBR222C 0.6 1.2 1.3 0.8 0.7 1.3 1.0 0.6 0.7 1.0 YCL009C 0.6 0.9 2.0 0.5 0.7 1.8 1.3 1.1 0.9 1.6 YCL064C 0.6 0.6 0.8 0.8 1.4 3.3 13.4 2.4 1.7 5.2 YCR098C 1.6 3.0 1.7 2.0 1.4 1.6 1.2 1.0 1.4 2.4 YDR502C 1.2 2.8 2.4 1.2 1.5 1.5 0.9 0.9 1.6 0.9 YER026C 0.8 0.6 3.3 1.0 1.2 2.5 1.6 0.8 0.9 1.5 YHR137W 0.7 1.0 2.4 1.7 1.0 0.7 0.4 0.4 0.2 0.9 YMR189W 0.7 0.8 1.9 2.8 0.4 1.9 0.8 0.4 0.7 0.9 YNL106C 1.0 1.4 0.8 1.5 0.8 1.0 0.9 0.8 0.7 1.4 YNL169C 0.7 1.4 1.4 1.2 0.7 1.4 0.7 0.8 1.1 1.1 YNL322C 0.8 0.9 1.9 0.8 1.4 1.1 0.9 0.7 0.7 0.8 YAL038W 1.0 1.0 3.0 1.4 1.4 1.3 0.9 1.1 0.1 1.1 YBR023C 0.5 0.8 1.3 1.1 0.8 0.5 0.7 0.5 0.3 0.4 YCR048W 0.5 1.1 1.0 0.6 0.9 0.2 0.9 0.8 0.8 0.5 YDR380W 0.8 0.8 0.8 1.7 1.1 0.4 0.5 0.2 0.2 0.3 YER069W 1.3 0.8 3.3 1.4 1.5 1.3 1.0 1.5 0.8 10.4 YGL022W 0.5 0.8 1.4 0.3 1.0 0.9 0.7 0.4 0.9 0.4 YGL126W 0.6 1.3 1.4 0.8 1.1 1.6 0.7 1.6 0.7 YGL209W 1.2 1.6 1.1 2.6 0.7 1.0 1.0 1.1 0.6 0.4 YGR282C 1.3 0.7 4.6 1.9 1.0 2.2 1.1 1.0 0.8 0.8 YIL154C 0.8 1.3 1.9 0.8 0.9 1.1 1.3 0.6 2.4 1.0 YJL088W 0.9 0.8 2.2 0.5 0.9 2.8 1.3 3.2 4.1 YJR148W 0.7 1.4 2.0 3.5 0.6 2.0 2.1 0.6 0.7 3.0 YLR180W 1.3 1.4 2.4 1.0 0.8 1.2 0.6 0.9 0.8 0.9 YLR273C 1.4 1.0 1.3 2.4 1.2 1.2 1.3 2.8 2.4 YLR300W 0.9 0.8 0.8 1.0 0.8 1.1 0.5 0.8 0.0 0.5 YLR307W 0.9 0.4 0.7 3.3 1.4 1.2 1.5 1.2 0.6 0.7 YMR296C 0.6 0.7 1.2 2.6 0.4 0.4 0.6 0.5 0.4 0.6 YOL058W 0.8 0.5 1.7 0.9 1.2 0.8 0.4 1.6 0.1 15.7 YBR183W 1.8 1.5 2.0 2.9 0.9 2.5 1.7 1.0 0.4 2.0 YDR019C 1.4 0.5 1.7 4.0 0.9 4.8 1.4 0.7 0.4 0.7 YIL167W 3.3 1.6 2.0 1.0 1.0 7.7 1.2 1.9 6.9 12.7 YKR039W 1.4 3.5 1.3 1.7 1.0 2.8 1.0 1.0 1.9 2.0 YNL037C 1.4 1.8 1.7 1.1 1.7 2.8 2.8 1.0 0.6 3.2 YNR002C 1.3 1.6 1.0 2.0 1.2 2.3 1.2 1.0 3.9 1.6 YOL143C 1.0 1.4 1.2 1.2 0.9 3.5 1.3 1.2 0.8 1.0 YOR136W 1.0 0.9 3.5 1.0 1.5 3.9 3.2 1.1 0.3 3.4 YAL044C 1.5 1.1 1.0 3.0 0.8 2.2 1.0 0.8 0.4 0.6 YAL054C 1.2 1.1 1.4 1.6 1.1 2.2 1.1 1.1 8.9 4.1 YAR071W 1.6 0.8 1.0 0.7 1.6 2.0 0.3 1.4 0.3 0.3 YBL001C 1.1 1.5 1.0 1.6 1.0 2.4 1.3 1.0 1.5 0.9 YBR014C 1.1 1.2 0.8 0.9 1.4 2.0 1.4 1.2 1.3 0.8 YBR035C 1.1 1.0 1.7 1.1 1.3 2.3 1.5 1.5 2.2 1.5 YBR068C 1.1 1.0 1.9 2.5 1.4 1.9 1.0 0.8 2.5 YBR111C 1.0 0.9 1.0 1.7 1.3 3.0 2.2 1.7 1.9 1.9 YCR037C 0.7 1.0 0.8 0.8 1.3 1.8 1.0 0.7 0.6 0.6 YDL022W 0.9 2.6 6.9 1.5 0.7 2.1 1.5 0.8 1.2 1.8 YDR009W 1.4 0.8 1.5 1.0 1.2 2.4 1.4 1.2 1.3 2.0 YDR410C 0.8 2.0 1.3 0.9 1.1 2.5 1.4 0.9 1.2 1.5 YDR487C 2.2 0.9 1.3 1.1 1.3 2.3 1.3 1.8 2.7 2.3 YEL011W 2.0 1.6 1.7 6.3 1.1 2.8 2.7 0.9 2.5 1.6 YFR015C 1.2 0.8 3.2 2.1 1.2 3.0 7.3 0.7 0.3 1.8 YGL001C 1.0 1.0 1.4 1.1 1.5 2.8 1.4 1.1 0.8 0.8 YGL104C 0.8 2.0 2.1 1.8 1.0 2.1 1.2 0.8 4.6 2.1 YGL154C 1.3 1.4 1.5 0.9 1.0 1.7 0.7 1.2 2.0 1.4 YGL253W 0.8 1.0 3.2 0.7 1.3 2.4 1.7 1.1 0.3 1.4 YGR060W 0.7 0.6 0.9 0.7 1.9 2.5 0.5 1.0 0.5 0.4 YHR037W 0.7 0.9 1.3 1.6 0.9 1.8 1.2 1.0 0.9 2.2 YHR092C 2.3 1.0 7.5 2.5 1.4 1.7 0.5 1.5 0.2 0.9 YHR190W 0.8 3.9 1.2 1.2 1.8 1.7 1.9 1.2 2.4 1.9 YIL033C 0.8 1.3 3.3 1.3 0.7 2.0 1.1 0.7 2.4 1.3 YIR035C 1.4 1.8 0.9 1.6 0.7 2.1 1.3 1.3 0.7 1.2 YJL132W 1.0 0.7 0.8 1.6 1.3 2.0 1.7 1.0 1.6 1.4 YJL196C 0.9 0.9 2.5 1.3 1.1 2.0 0.7 0.7 1.1 0.9 YJR142W 1.2 0.6 1.1 1.1 1.3 2.4 1.7 1.0 0.6 0.8 YKL067W 1.1 1.9 2.1 1.4 1.9 2.2 2.6 1.2 0.9 1.6 YLR142W 4.4 2.7 1.1 6.1 1.3 3.1 1.2 2.1 3.1 4.4 YML110C 1.1 0.8 1.9 1.6 0.8 2.6 2.0 1.4 2.7 2.2 YMR272C 0.7 1.0 1.6 0.7 1.1 2.6 1.0 0.8 0.4 0.6 YNL130C 0.6 0.7 2.4 0.7 0.8 2.4 1.3 0.8 1.7 2.4 YPR006C 1.9 1.5 0.5 1.9 2.0 2.4 2.8 1.5 1.5 3.9 YBR050C 2.4 1.9 1.9 3.1 1.0 4.1 2.6 1.7 5.8 3.2 YBR145W 1.5 0.7 2.8 0.9 1.1 11.5 58.8 1.0 0.1 1.1 YBR299W 1.8 0.9 1.1 3.5 1.6 0.8 3.6 2.2 1.1 5.3 YEL020C 1.0 1.5 0.8 2.9 1.5 1.3 2.4 1.2 1.4 1.1 YGL039W 0.8 1.4 2.1 1.3 1.3 1.7 4.2 1.3 0.7 2.8 YGL134W 0.9 1.3 0.5 0.8 1.4 1.2 2.3 1.4 1.1 1.4 YJR159W 1.4 2.3 1.3 1.7 0.9 1.4 2.3 2.7 5.2 2.8 YOL157C 1.0 1.1 1.3 2.5 1.4 0.9 2.7 1.4 2.3 4.8 YOR344C 1.1 1.1 0.4 0.7 1.9 2.0 2.4 1.4 0.3 0.9 YPL265W 0.7 0.4 2.3 1.1 1.0 2.3 8.9 2.3 0.2 1.2 YBR126C 0.8 1.9 5.6 1.2 0.7 2.9 2.3 0.6 1.7 YCR005C 1.1 1.9 2.0 1.2 0.9 1.6 4.4 1.2 1.5 1.5 YDR452W 1.1 1.1 1.3 0.8 1.2 2.0 1.9 1.0 1.4 1.3 YGR019W 1.2 0.8 1.4 1.7 0.8 2.4 2.4 1.2 2.9 YGR255C 0.9 1.4 1.4 1.5 1.3 3.2 1.8 1.0 2.5 1.8 YIL098C 1.4 1.6 0.5 2.0 1.7 1.7 2.2 1.6 1.9 1.9 YIL172C 1.1 1.1 1.6 1.7 1.3 2.5 1.6 2.8 7.1 YLR100W 0.8 1.4 1.3 1.9 1.8 1.8 2.3 1.0 0.9 1.0 YOR221C 0.8 1.0 0.9 1.1 1.7 0.8 2.1 0.9 1.4 1.7 YPL123C 1.2 0.8 1.8 3.0 0.8 1.9 2.7 1.2 4.2 2.3 YBR093C 2.9 1.2 1.7 1.3 1.1 0.6 0.3 1.7 0.1 0.5 YBR196C 0.8 0.6 3.9 1.4 0.8 0.8 1.4 1.1 0.3 0.9 YER023W 0.8 0.6 1.2 1.2 0.8 1.3 0.7 0.9 1.1 0.6 YFL055W 2.0 6.7 1.3 2.5 1.5 1.1 1.4 1.3 23.9 6.5 YIL124W 0.9 0.8 2.8 1.6 0.9 1.2 1.3 0.9 1.0 0.7 YMR318C 1.4 2.4 2.2 0.7 1.2 2.1 0.8 3.6 2.3 4.8 YBR067C 1.6 2.5 2.8 0.9 1.1 1.1 1.1 1.1 1.7 1.0 YBR115C 0.6 0.7 1.4 0.4 0.7 0.9 1.1 1.3 0.8 1.6 YDL131W 1.1 0.9 1.8 1.0 1.0 0.9 0.7 2.2 0.8 2.7 YDL168W 2.3 2.0 2.1 0.9 1.2 1.4 1.1 1.7 8.2 4.7 YDR216W 1.3 1.1 2.0 2.6 0.8 1.3 1.0 1.0 2.5 2.7 YDR253C 5.7 6.4 1.4 3.2 0.9 0.8 1.0 1.7 14.8 6.3 YDR513W 2.2 2.5 2.3 2.6 0.9 2.1 1.6 1.6 4.6 3.1 YER061C 0.9 0.9 1.2 2.5 0.8 0.4 0.9 0.7 0.3 0.7 YFL052W 1.3 0.8 0.7 2.3 1.5 2.1 1.4 1.3 0.6 1.2 YFL058W 1.2 1.7 1.1 1.4 1.1 2.0 0.9 1.7 3.2 2.4 YFR030W 3.1 5.5 8.5 0.5 0.8 1.8 1.1 1.7 24.1 9.0 YGL202W 0.8 0.7 2.2 0.7 0.7 0.7 0.6 1.0 1.3 1.7 YGR070W 1.1 1.0 2.0 1.5 1.4 1.4 1.8 1.1 1.5 YHL036W 2.2 4.8 3.4 2.0 1.3 1.3 1.0 1.2 9.0 4.4 YHR104W 1.0 4.1 15.7 1.9 1.1 1.2 1.5 1.1 4.8 2.3 YJL045W 1.8 2.2 1.6 5.3 0.7 0.6 0.7 0.9 9.7 1.6 YJL060W 1.8 2.6 9.6 1.0 1.4 1.3 1.3 0.8 5.3 2.8 YJL155C 2.1 5.0 0.8 2.4 0.8 0.8 2.0 1.5 3.8 2.8 YJR109C 0.8 0.7 1.4 0.9 0.7 0.9 0.8 1.0 1.8 4.3 YJR156C 1.6 3.2 2.4 1.8 0.9 0.9 1.3 1.5 3.4 2.8 YLR092W 5.0 7.5 1.4 0.6 1.3 1.0 1.3 1.5 12.7 5.8 YMR081C 3.5 1.4 2.0 5.8 1.7 1.1 0.9 1.7 0.3 2.2 YMR250W 0.9 5.1 5.6 1.3 0.6 4.5 3.0 0.9 6.1 2.4 YNL277W 5.7 10.3 5.3 0.6 1.1 1.7 1.4 2.2 55.0 10.9 YOR184W 1.1 0.9 2.1 2.1 1.0 0.6 1.2 0.7 0.9 0.7 YPR160W 1.4 3.8 3.6 3.3 0.7 4.5 1.8 0.9 0.9 1.3 YDL182W 0.8 0.7 1.3 0.8 1.3 1.0 1.0 2.9 0.8 2.4 YBR291C 2.0 0.9 1.0 1.5 0.9 1.1 0.9 2.2 0.9 1.0 YIL094C 1.5 0.4 0.8 0.7 1.4 1.2 1.3 3.6 0.3 0.4 YNR050C 1.7 0.5 1.2 0.6 1.3 0.9 1.0 2.2 0.4 0.7 YDL244W 1.1 3.5 1.8 1.6 0.9 1.3 1.7 1.8 2.5 3.7 YDR054C 1.3 1.0 0.7 1.4 0.7 1.0 1.1 1.5 2.9 3.2 YDR353W 0.9 1.6 3.4 1.6 0.6 0.9 1.0 1.1 2.0 5.1 YEL070W 1.4 0.9 1.6 3.4 1.3 1.2 1.3 1.2 1.9 13.0 YIL168W 2.8 1.4 1.0 1.2 1.4 0.7 1.3 1.6 7.8 19.3 YJL221C 1.1 1.0 1.1 1.3 0.9 6.6 2.5 1.8 2.7 4.4 YJR095W 1.2 20.5 1.9 6.7 1.2 1.5 2.0 0.9 0.5 6.3 YKL085W 1.4 2.3 1.6 1.2 1.2 1.9 1.5 1.2 1.9 3.0 YKL188C 1.3 0.7 1.9 2.4 1.0 0.8 1.1 0.7 2.5 2.8 YKL217W 1.8 2.4 1.0 2.1 1.1 1.2 1.6 1.1 0.9 4.1 YKR061W 2.0 0.9 0.5 1.9 1.2 1.2 1.4 1.5 1.5 2.6 YLR174W 1.2 1.5 1.7 2.1 0.9 0.9 1.6 1.1 2.5 8.3 YLR260W 1.1 1.5 1.5 2.4 1.2 1.0 1.2 1.2 2.6 3.2 YNL009W 1.1 1.9 2.0 1.4 1.4 1.1 1.2 1.1 1.4 3.3 YNL117W 0.9 4.7 1.7 0.8 0.8 1.1 1.7 12.8 4.4 YNL183C 0.9 3.5 6.4 1.3 0.7 1.2 1.3 0.9 4.8 4.3 YNR073C 1.1 1.4 0.8 2.7 1.4 1.7 2.2 1.5 2.5 16.8 YPL161C 1.0 1.7 1.1 1.1 0.8 0.7 1.3 1.8 1.2 2.7 YAL061W 1.7 2.4 3.3 3.8 1.0 1.0 2.0 0.8 5.5 1.4 YAL067C 2.7 7.5 1.5 1.4 0.7 1.2 0.8 1.1 7.6 2.9 YBL033C 1.3 1.9 2.4 1.0 1.1 0.4 0.9 1.4 6.6 4.2 YBL086C 0.8 0.5 1.0 0.6 1.3 0.7 1.0 1.1 3.3 1.4 YBR117C 0.8 1.6 1.5 1.4 0.9 2.3 1.0 0.7 5.9 1.5 YBR213W 1.0 1.6 1.0 0.5 1.1 2.4 1.3 1.3 11.4 2.3 YCR036W 1.3 1.2 1.3 1.3 1.5 1.4 1.5 1.1 2.6 1.5 YDL132W 0.8 1.2 1.1 0.7 1.3 0.9 1.4 1.0 3.8 2.4 YER014W 1.0 0.9 0.9 0.6 0.8 4.0 1.2 3.5 1.1 YER042W 3.0 2.2 3.1 1.0 1.1 1.6 1.1 1.7 6.8 2.1 YER090W 1.0 1.1 2.0 0.7 1.3 0.7 0.9 1.4 3.7 2.5 YGL026C 0.7 9.3 1.9 0.6 1.2 1.7 0.9 0.8 3.7 1.5 YGL252C 1.1 2.4 1.4 0.7 1.3 0.8 1.4 1.2 2.7 1.7 YGL254W 1.2 1.1 0.8 0.6 1.1 0.7 1.3 1.4 3.1 1.8 YGR276C 0.9 0.8 0.3 1.3 1.5 0.7 1.9 1.5 4.5 2.2 YHR106W 0.9 1.7 1.7 1.5 1.7 1.3 1.2 1.0 2.8 2.5 YIL046W 1.5 2.7 1.6 0.7 1.4 0.9 1.0 1.0 10.7 2.5 YJL071W 1.0 1.5 1.3 1.6 1.4 1.0 1.3 1.1 2.8 2.2 YJR139C 1.4 2.6 2.9 1.1 1.2 1.8 1.3 1.1 4.1 1.9 YKR069W 3.4 6.3 5.0 3.1 0.7 0.5 1.0 1.2 10.9 9.0 YLL061W 3.6 2.8 9.2 0.4 0.8 0.8 0.9 1.4 3.7 5.5 YLR070C 1.0 1.3 1.4 1.1 0.7 1.1 1.3 1.0 3.5 1.6 YLR099C 2.0 2.2 1.4 0.8 0.9 0.4 0.2 1.2 3.6 1.1 YLR157C 1.1 1.1 3.4 1.1 1.3 1.9 1.9 1.5 5.1 1.8 YLR160C 1.2 1.4 3.9 1.1 1.3 1.8 1.9 2.0 4.8 1.8 YLR164W 1.0 2.4 0.3 1.0 1.2 1.2 1.1 1.2 5.3 2.0 YML042W 0.9 1.4 1.5 2.2 1.0 0.9 0.8 1.6 3.8 2.4 YOL049W 0.9 1.1 1.3 0.9 1.4 0.6 1.1 1.0 3.0 1.9 YOL064C 1.4 2.1 1.1 0.6 0.9 1.4 1.2 1.0 8.7 2.7 YOR377W 0.6 0.6 0.6 1.0 1.4 1.6 1.6 1.0 3.8 1.1 YPL031C 0.9 2.0 1.4 0.8 1.5 1.8 1.6 1.0 5.7 1.4 YPL113C 1.4 1.7 0.4 2.4 1.3 1.0 1.9 1.4 5.5 2.0 YPL274W 0.8 4.2 3.8 0.8 0.6 1.1 0.7 0.9 4.1 3.6 YPR048W 1.3 2.0 0.9 1.1 0.9 0.6 0.9 1.5 4.0 2.1 YBR001C 0.9 1.4 1.1 1.4 0.9 1.1 0.9 1.3 2.3 2.1 YBR018C 0.9 1.1 1.9 2.9 0.9 0.7 1.4 0.6 1.3 1.7 YBR204C 1.0 1.0 1.5 1.8 1.1 0.9 1.7 1.1 1.8 1.9 YBR241C 0.9 9.3 2.6 0.9 0.9 1.5 1.4 0.7 29.8 2.2 YCR105W 2.2 1.2 1.2 3.0 0.9 1.0 1.0 1.4 2.0 3.9 YDR287W 1.1 8.4 1.9 1.2 1.2 1.6 1.2 1.2 2.5 1.8 YDR294C 0.7 1.1 1.9 1.2 0.9 0.7 1.0 1.0 2.0 2.9 YER052C 1.1 1.0 3.6 1.1 0.6 0.6 0.5 1.0 2.7 2.4 YFL021W 0.8 1.4 2.4 1.7 1.1 0.8 0.8 0.6 2.7 1.2 YGL040C 0.7 1.2 1.4 0.9 1.3 2.0 1.1 1.0 2.1 1.9 YGL125W 1.0 3.2 4.3 0.7 0.9 1.7 0.8 2.1 2.1 YGR007W 1.3 1.7 0.7 1.6 0.6 0.8 1.2 1.1 2.2 2.3 YGR155W 1.3 4.4 1.2 0.6 1.3 1.6 1.1 1.4 2.4 1.7 YIL099W 0.9 1.6 1.5 0.4 0.8 101.4 1.0 2.2 1.8 YIL170W 1.1 1.0 2.5 2.2 0.9 8.8 0.5 1.2 5.7 3.2 YIR031C 0.8 1.6 0.6 0.6 1.6 1.7 1.4 1.0 2.6 1.0 YIR032C 1.1 1.9 1.3 2.6 1.0 0.6 1.0 1.2 2.6 2.3 YJL128C 0.8 1.4 0.4 0.8 1.2 1.3 1.8 0.9 2.0 1.7 YJR090C 0.8 1.0 0.6 0.8 1.2 1.2 0.8 0.8 1.9 1.2 YJR103W 1.1 3.8 1.2 1.6 0.7 0.6 0.6 0.8 1.8 3.0 YJR153W 1.1 1.7 1.1 0.8 0.9 0.4 1.3 0.9 2.4 1.6 YKL192C 1.1 1.0 3.7 1.1 1.1 1.8 1.1 0.9 3.5 1.6 YLR025W 1.2 5.1 0.7 1.1 1.9 1.5 1.7 1.5 2.4 1.5 YML051W 1.0 1.4 1.8 0.9 1.0 0.7 0.9 0.9 2.0 1.5 YML099C 0.6 1.0 1.1 1.3 1.0 0.5 1.0 0.7 2.2 1.7 YMR056C 1.1 1.3 1.7 1.0 1.1 0.9 1.4 1.2 1.8 1.1 YNL257C 0.7 1.0 0.9 0.8 0.9 2.0 1.1 1.1 2.1 1.4 YNL264C 1.0 2.4 1.3 1.0 0.8 1.4 1.5 1.1 3.3 1.3 YNR071C 1.4 1.0 0.9 3.2 1.1 0.9 1.4 1.2 3.1 7.0 YOL065C 1.0 1.7 1.6 1.3 0.8 1.3 1.9 1.0 2.1 1.8 YOL067C 0.8 0.9 0.9 1.4 0.7 0.3 0.7 1.0 2.1 1.3 YPL147W 1.0 0.8 2.3 1.2 1.2 1.1 1.0 0.9 2.4 2.4 YDR043C 2.8 1.1 1.2 6.9 1.7 1.4 1.3 1.2 1.0 2.7 YGR180C 3.1 1.1 1.9 1.0 2.0 0.6 0.5 1.0 1.4 1.5 YJL026W 2.5 2.4 2.9 1.0 1.7 1.4 0.5 1.2 1.0 1.1 YGR087C 1.0 15.0 1.7 0.6 1.0 1.1 1.0 0.8 0.2 0.9 YGL256W 0.9 5.3 1.1 1.3 0.7 0.7 0.5 1.0 0.4 1.2 YAL039C 1.1 2.2 1.7 1.0 1.1 0.8 1.0 1.2 1.6 2.2 YJR107W 1.0 3.1 1.5 1.8 0.7 1.5 1.3 1.3 1.4 0.9 YNL142W 0.7 2.4 2.5 0.8 1.3 0.9 1.1 0.8 0.9 0.6 YDL210W 1.2 2.2 2.7 1.1 0.9 1.3 0.8 1.1 1.2 1.4 YGL055W 1.1 1.8 0.3 2.5 1.5 1.6 0.6 1.4 0.2 0.7 YCL025C 1.1 4.6 2.5 1.7 0.9 0.9 0.7 0.7 0.3 0.3 YBR132C 0.9 1.9 2.4 1.8 0.8 1.2 1.1 0.8 0.8 1.1 YHL018W 0.8 1.5 0.5 0.5 0.9 0.4 1.2 0.8 0.8 0.6 YPL038W 0.8 1.5 0.2 1.1 1.4 0.5 1.0 1.2 0.9 0.7 YKR053C 0.9 2.0 1.0 1.2 1.0 1.1 1.7 0.9 0.8 1.8 YNL256W 0.7 1.6 0.6 0.6 1.0 0.5 0.6 0.9 0.8 0.6 YLR377C 1.1 2.6 1.8 1.2 1.0 0.7 0.9 0.7 1.8 1.6 YBR253W 1.3 4.4 0.4 1.1 1.4 1.3 1.4 1.8 1.8 1.5 YBL030C 1.0 0.9 4.5 0.9 0.7 1.1 0.9 0.8 0.4 0.9 YBR221C 0.8 0.7 3.2 1.5 1.3 1.7 1.5 0.8 1.0 1.3 YDR342C 2.8 1.1 12.2 5.7 1.6 1.1 0.8 1.2 0.2 2.2 YDR343C 1.2 1.0 20.6 4.6 1.3 1.3 0.7 1.2 0.3 2.1 YEL034W 0.9 0.6 3.3 0.9 1.4 0.9 0.4 0.9 0.8 1.0 YHR094C 0.7 1.2 5.3 1.6 1.1 1.6 0.8 1.2 0.3 1.2 YIL162W 1.3 1.5 6.8 2.4 1.2 1.0 1.2 1.6 0.8 3.7 YJR105W 0.6 0.7 3.0 0.8 0.7 0.3 0.5 0.8 0.9 0.5 YLR134W 0.8 0.6 2.3 0.8 1.3 2.5 1.1 0.8 0.1 0.7 YLR258W 1.5 1.0 4.2 3.5 0.9 1.8 1.8 0.9 0.8 1.3 YML058W 1.9 1.2 5.8 1.9 0.6 0.6 0.6 0.7 1.1 1.2 YMR083W 1.4 1.7 2.6 1.1 1.5 1.8 1.7 1.1 0.4 1.1 YOR178C 1.4 1.3 4.8 2.3 1.0 2.7 0.9 0.9 0.2 1.7 YPL028W 0.7 0.9 2.6 0.9 1.0 1.2 1.3 0.9 1.2 0.8 YPR113W 1.1 0.8 3.7 1.3 2.0 1.1 1.2 0.9 0.4 0.8 YPR183W 0.9 1.5 3.5 0.8 0.9 1.2 1.2 1.0 0.9 0.6 YBR011C 1.3 1.8 2.5 1.1 0.9 2.0 1.1 1.3 2.2 1.0 YCR034W 0.8 0.4 2.5 0.9 0.9 0.3 0.3 0.9 0.1 0.2 YDR050C 1.6 1.3 2.3 1.8 0.9 1.7 1.5 1.3 0.4 1.3 YDR178W 2.0 2.0 3.4 2.2 0.9 2.1 0.6 0.9 0.9 0.8 YDR284C 0.8 1.5 3.0 2.9 0.8 1.8 1.4 0.9 0.9 1.0 YDR345C 0.8 0.9 5.6 2.6 1.3 1.2 1.1 1.2 0.2 1.1 YDR400W 1.0 2.0 2.2 0.7 1.0 1.1 0.6 1.4 1.1 1.4 YEL063C 0.7 0.8 2.4 1.3 1.2 1.3 0.7 0.6 0.8 1.7 YER081W 1.6 1.9 2.7 1.4 1.1 1.1 0.5 0.6 1.8 1.1 YER120W 0.9 1.1 2.5 0.8 0.8 1.5 0.9 0.6 0.8 0.9 YFL011W 1.2 0.7 3.7 3.3 1.3 1.0 0.8 0.8 0.3 1.6 YGL012W 1.0 0.8 3.0 1.2 1.5 1.6 0.9 0.8 0.3 0.9 YGR191W 0.8 0.7 1.6 1.5 0.8 1.1 0.7 0.7 0.1 0.7 YGR204W 0.5 1.1 2.7 1.3 0.6 0.6 0.8 0.4 0.9 2.3 YHR025W 0.6 0.8 2.4 0.6 0.9 0.8 0.8 0.8 0.2 0.4 YHR123W 0.7 1.2 1.8 1.0 1.0 0.9 0.8 0.8 1.1 YJL121C 1.0 0.5 1.9 0.8 1.0 1.1 0.7 1.0 0.1 0.4 YJR077C 1.1 1.1 2.0 1.6 0.9 0.9 0.7 0.8 0.4 0.7 YJR143C 0.6 0.6 2.1 0.8 1.6 0.6 0.5 0.7 0.1 0.3 YKL060C 1.6 0.8 2.5 1.0 1.6 1.3 1.2 1.1 0.3 0.8 YKL148C 0.9 0.8 3.7 0.7 0.8 0.5 0.6 0.8 1.7 1.7 YKL157W 0.7 1.0 2.3 1.3 1.5 1.5 1.9 1.1 1.7 1.9 YLR044C 0.8 0.6 2.2 0.9 1.7 1.5 1.3 0.7 0.0 1.2 YLR056W 1.0 0.6 2.5 0.8 1.6 1.2 0.8 0.9 0.0 0.5 YLR058C 0.9 0.8 5.5 2.6 0.7 0.9 0.5 0.3 0.2 0.1 YLR081W 1.3 0.8 2.8 3.6 1.0 0.9 0.7 0.9 0.1 2.2 YLR089C 0.9 1.2 2.1 0.9 0.8 1.5 1.6 0.7 0.5 0.8 YLR284C 0.9 1.0 3.8 1.9 1.6 0.9 0.8 1.2 0.9 0.9 YLR304C 0.7 0.6 5.0 0.7 0.6 1.9 0.6 0.6 0.1 2.2 YLR354C 1.1 2.5 2.3 1.5 1.6 1.5 1.1 1.4 0.4 0.9 YLR372W 0.7 0.3 1.7 0.8 1.4 0.5 0.2 0.9 0.0 0.1 YML022W 0.9 0.6 2.0 1.1 1.3 0.8 0.6 1.1 0.3 0.6 YMR011W 1.3 1.0 9.4 5.5 0.9 0.6 0.8 1.1 0.0 0.7 YMR015C 0.7 0.7 1.9 0.9 1.7 1.3 0.4 0.7 0.1 0.3 YMR205C 0.5 0.7 2.3 0.8 1.2 1.2 0.9 0.7 0.3 0.8 YMR261C 0.7 1.6 3.6 0.8 0.9 0.6 1.3 0.7 1.6 1.3 YMR323W 0.8 1.1 2.9 1.1 0.7 0.4 1.1 0.8 0.5 1.3 YOL086C 1.1 0.5 2.2 1.1 1.9 1.7 1.9 0.8 0.1 1.2 YOL156W 1.1 0.7 2.5 1.1 1.2 1.2 1.0 1.0 2.3 2.1 YOR002W 0.8 1.1 1.9 0.9 1.1 1.1 1.0 0.9 0.8 0.9 YOR085W 0.7 0.8 1.9 1.0 1.0 0.6 0.6 0.7 0.5 0.6 YOR108W 0.8 0.9 2.3 0.6 1.1 1.6 1.2 0.9 0.4 1.1 YOR128C 0.9 0.7 2.1 2.1 1.1 1.0 0.7 0.6 0.3 0.4 YOR142W 1.0 1.2 3.4 1.0 1.4 1.6 1.0 0.8 1.1 1.5 YOR176W 0.7 2.6 2.7 0.9 1.0 0.9 0.5 1.0 1.0 0.5 YPL057C 1.9 1.1 3.2 3.1 1.9 0.6 0.6 1.0 0.4 1.4 YPL135W 0.9 1.2 2.5 1.2 1.6 1.3 1.2 1.0 0.5 2.8 YCR010C 1.6 1.6 1.6 4.2 1.7 1.3 1.3 0.8 0.9 4.7 YBR003W 0.9 0.8 1.0 1.9 0.7 1.2 1.1 0.9 1.0 1.3 YBR020W 1.0 0.5 1.9 1.9 1.0 0.8 0.7 1.0 −0.4 1.1 YDR123C 1.2 0.8 0.4 2.1 1.6 0.7 0.9 1.3 0.5 0.6 YDR277C 1.6 1.2 1.0 3.0 0.8 1.1 1.2 1.7 0.2 0.9 YDR408C 1.0 1.0 1.4 4.1 0.9 0.9 0.8 0.7 0.3 0.5 YDR483W 1.1 1.0 1.3 2.0 0.7 1.5 0.8 1.0 0.4 1.1 YGL115W 0.9 0.6 1.2 2.0 1.2 1.2 1.4 1.0 1.2 1.2 YGR096W 1.5 1.0 1.1 4.6 1.2 1.7 0.9 1.0 0.8 0.8 YGR288W 0.9 0.5 1.0 2.6 0.8 1.4 1.0 1.6 2.6 YHR210C 1.3 1.0 0.6 5.2 1.8 0.7 1.9 1.3 −0.1 0.9 YIL006W 1.0 1.1 1.4 2.9 0.8 0.3 0.8 0.6 0.9 1.1 YKR034W 0.9 1.5 1.1 4.7 0.9 0.9 0.7 1.5 0.5 0.6 YLR006C 0.7 0.7 0.9 6.2 1.6 0.9 1.1 0.9 1.1 1.1 YNL025C 0.9 1.4 1.4 12.8 0.7 0.5 1.2 1.0 1.1 1.8 YOL116W 1.1 1.0 0.9 2.8 1.7 0.7 1.5 1.3 0.6 1.8 YOR103C 1.1 0.8 1.3 1.8 1.5 1.0 1.2 1.0 0.8 0.9 YOR251C 1.1 1.0 1.3 1.8 0.8 0.9 1.0 1.1 0.8 0.8 YOR348C 1.1 0.7 1.2 2.0 0.9 0.7 0.8 0.8 0.5 0.4 YPL148C 1.2 0.8 0.9 2.3 1.1 0.6 1.0 0.9 0.7 1.5 YGL205W 0.9 0.9 0.7 0.8 1.1 1.6 0.8 1.2 0.5 0.6 YNL192W 1.1 1.2 1.5 1.6 0.9 0.6 1.0 0.8 0.6 1.8 YOL108C 1.4 1.5 0.4 1.9 2.1 0.9 1.1 1.3 1.6 0.9 YPR165W 1.3 0.7 1.6 1.0 1.5 1.8 1.0 1.0 0.9 0.7 YDR073W 1.7 0.9 0.7 1.4 1.2 1.3 1.2 1.3 0.5 1.2 YER015W 0.7 0.9 1.1 1.5 1.3 0.9 1.2 1.1 0.4 0.9 YJL167W 0.9 1.4 1.4 1.1 0.7 1.3 1.5 1.5 0.9 0.9 YJL216C 0.8 4.7 2.2 0.9 0.8 1.5 1.9 1.5 1.3 YKR009C 1.0 1.2 1.5 0.9 1.0 1.8 1.0 0.9 2.4 2.1 YOR180C 0.8 1.1 1.0 1.0 1.0 0.7 0.8 0.9 0.3 0.4 YBR036C 0.8 1.7 1.8 1.2 1.2 1.3 1.3 0.7 1.0 1.0 YDR297W 1.5 0.8 0.8 1.1 0.9 1.4 0.6 1.5 0.3 0.7 YDR387C 0.8 0.9 1.2 2.2 0.9 1.2 1.3 0.7 1.4 2.0 YOL096C 1.1 1.0 1.2 1.6 1.2 1.3 1.7 1.0 1.3 1.4 YPR184W 1.2 1.4 5.7 2.2 0.9 1.5 1.3 0.7 1.9 3.2 YBR298C 1.1 1.0 1.6 2.3 1.4 0.4 1.7 0.5 0.3 1.1 YDL078C 0.7 1.1 1.2 0.8 1.3 1.1 1.7 1.0 1.1 1.0 YDL215C 1.0 1.5 1.0 1.6 1.5 0.9 1.9 1.1 1.7 2.4 YGL035C 0.7 1.4 4.3 1.4 1.1 0.6 1.2 1.3 0.9 1.5 YGR287C 1.3 1.0 1.3 1.5 0.8 0.8 2.2 1.3 2.6 4.2 YJL070C 1.3 0.9 1.1 1.2 1.3 2.0 1.4 1.1 1.0 1.1 YLR351C 1.0 1.4 1.3 1.5 1.3 1.4 1.4 1.2 0.8 1.2 YLR375W 0.9 1.5 0.9 0.9 1.0 1.3 0.9 1.0 1.6 1.2 YMR267W 0.8 1.8 0.7 0.9 1.0 1.4 1.2 1.5 0.4 0.8 YMR278W 0.7 1.7 1.4 1.0 1.2 1.3 1.8 1.1 1.4 1.7 YMR293C 0.9 1.5 1.6 2.2 0.6 0.5 1.2 1.0 0.7 1.3 YNR072W 1.1 1.5 0.5 0.7 1.0 0.9 1.5 0.9 0.7 1.8 YOR363C 0.8 2.0 0.9 1.3 0.7 1.2 0.7 1.1 1.2 1.6 yeast The level of expressed mRNA in the absence of chemical substance genes (11) (12) (13) (14) (15) (16) (17) (18) Intensity YCR107W 23.0 0.9 4.0 8.3 4.8 3.1 1.3 1.1 0.59 YDL243C 19.6 1.1 4.1 12.0 4.2 3.0 1.8 1.5 0.76 YFL014W 5.0 4.3 15.2 7.3 6.3 14.2 1.5 8.8 2.14 YFL056C 68.3 1.0 4.7 7.8 5.0 3.4 1.0 1.1 0.55 YFL057C 27.7 1.0 4.1 23.4 3.1 3.9 1.6 1.3 0.71 YJR155W 15.4 1.0 5.7 9.4 2.6 5.6 1.3 1.4 0.64 YNL331C 21.8 0.9 3.1 7.5 2.3 4.0 1.7 1.3 0.58 YNL332W 2.6 1.2 2.1 3.0 5.4 2.2 1.0 1.0 0.24 YOL165C 17.6 0.8 3.7 9.1 3.0 1.8 1.6 1.0 0.69 YPR167C 1.9 1.3 1.9 4.2 0.9 0.9 1.7 1.4 0.54 YBR256C 3.2 1.7 3.5 5.6 1.6 3.0 2.6 3.3 1.97 YBR296C 1.5 1.6 2.0 2.3 1.7 0.3 3.8 4.0 0.54 YDL021W 4.7 2.4 5.3 3.7 0.7 7.3 1.9 3.2 0.47 YFL061W 1.1 0.9 1.2 6.0 2.1 1.0 1.2 0.9 0.31 YGR043C 3.6 3.3 6.9 4.1 3.0 13.7 1.6 4.8 0.66 YHR112C 1.5 1.9 3.9 2.4 2.0 2.7 1.6 1.8 0.55 YIR030C 1.4 0.9 1.3 2.9 0.7 0.8 0.9 1.0 0.42 YJR010W 2.9 1.4 3.2 5.4 1.7 1.7 1.2 1.0 0.56 YKL001C 2.6 2.1 1.6 6.2 1.1 1.8 2.7 1.7 0.91 YKR097W 0.8 1.8 17.5 2.1 2.5 2.2 1.1 1.5 0.16 YLR303W 9.8 4.3 9.9 3.8 5.8 3.4 1.5 1.4 1.42 YNL274C 4.0 1.1 2.3 3.3 2.5 6.4 1.4 2.6 0.85 YOL151W 9.0 4.6 16.9 4.0 2.8 3.7 4.0 5.6 1.12 YOR226C 1.5 0.6 0.9 2.7 1.0 0.7 1.0 0.7 0.58 YJL153C 0.7 10.2 38.0 1.4 37.0 1.0 6.5 1.8 0.27 YOR153W 1.0 4.0 11.8 0.3 3.6 1.6 2.5 3.1 1.91 YPL088W 1.1 3.6 4.8 1.6 3.2 4.3 9.1 8.3 0.69 YDL124W 3.4 2.4 6.0 1.6 3.4 3.6 2.2 2.6 2.43 YDL174C 0.9 2.8 5.9 1.1 0.6 5.1 2.2 4.0 0.63 YGL156W 2.1 2.6 6.0 1.6 3.0 4.1 1.4 1.9 0.29 YGR157W 1.0 1.8 4.8 0.7 4.6 1.0 0.8 1.3 2.10 YHR043C 1.6 2.2 2.7 1.3 2.1 2.2 1.4 1.7 1.38 YHR044C 1.7 2.3 4.3 1.3 1.5 2.4 1.3 1.4 1.12 YJR073C 2.8 4.1 10.0 2.3 28.9 3.7 2.9 2.6 0.99 YOR303W 0.9 1.9 3.3 1.6 4.1 1.2 1.2 0.8 1.47 YBR294W 1.2 1.0 3.1 1.3 1.0 0.9 1.0 0.9 0.18 YCL043C 1.7 1.5 4.1 0.6 5.7 0.8 0.9 1.0 2.37 YCL050C 1.3 1.2 2.8 1.2 0.8 0.7 1.0 1.0 2.20 YCR012W 1.8 1.2 4.1 0.9 1.4 1.4 0.8 1.3 4.48 YDR158W 1.6 1.0 2.6 0.9 1.0 0.6 1.0 0.9 3.54 YDR204W 2.2 1.2 2.9 1.1 0.6 2.8 1.1 1.7 0.62 YDR313C 1.5 1.2 2.3 1.3 0.8 2.9 1.1 1.3 0.84 YDR368W 1.8 1.4 2.6 2.0 1.2 2.3 1.1 2.0 1.70 YER091C 3.2 2.0 5.4 1.2 10.2 2.7 1.2 1.0 1.23 YFR053C 1.5 1.7 3.0 0.6 0.6 3.0 1.4 2.2 4.17 YGL062W 0.7 1.6 4.5 1.2 2.7 1.5 1.1 0.9 0.77 YGL157W 1.4 1.5 4.8 1.2 5.1 1.7 1.8 2.3 1.69 YGL184C 1.7 2.6 7.4 1.4 0.4 1.5 1.0 0.9 0.16 YGR032W 1.5 1.5 3.9 1.1 5.4 1.5 3.2 2.8 1.18 YGR124W 1.1 1.1 2.3 0.5 1.5 0.3 0.7 0.6 3.56 YGR192C 2.3 2.2 3.4 1.0 1.9 1.1 1.1 1.3 7.49 YGR244C 1.8 1.9 2.6 1.2 2.0 2.6 1.9 3.1 1.12 YGR254W 1.3 1.7 3.1 0.6 2.4 1.4 1.3 1.2 7.01 YHR018C 1.4 1.4 3.3 1.0 4.4 1.0 1.9 1.2 1.21 YIL160C 2.4 1.0 2.3 1.5 5.6 8.8 2.4 3.0 0.27 YIR017C 4.2 1.2 3.4 1.9 2.3 3.0 1.5 1.3 0.36 YJL052W 4.3 2.4 5.6 1.3 2.3 2.3 1.2 1.9 6.19 YJR009C 1.1 1.5 2.7 1.0 2.1 1.5 1.1 1.3 5.86 YJR130C 1.7 1.0 2.9 1.1 0.9 1.5 1.1 1.3 0.62 YJR149W 0.7 1.0 3.5 1.4 1.4 2.4 1.1 1.2 0.34 YKL218C 1.7 1.2 5.1 1.4 0.8 3.1 2.5 2.6 0.60 YLR027C 1.6 1.3 2.5 1.0 1.4 0.9 1.3 1.3 1.39 YLR133W 0.6 1.5 3.3 1.1 1.9 1.0 1.1 1.3 0.36 YLR155C 2.0 1.1 3.3 1.1 1.2 2.2 1.4 2.2 1.63 YLR158C 2.4 1.1 3.2 1.2 1.1 2.1 1.4 2.0 1.57 YLR195C 0.8 1.3 2.3 0.7 0.9 0.8 0.9 1.0 1.55 YLR345W 2.5 1.6 3.5 1.5 1.0 1.2 1.2 1.4 2.65 YML004C 2.2 1.1 2.4 1.4 2.1 4.5 1.5 2.4 2.41 YML131W 14.4 1.1 2.4 2.7 2.2 1.6 2.5 3.0 1.15 YNL071W 1.6 1.3 2.5 0.8 1.1 1.1 1.0 1.2 1.61 YNL241C 3.0 2.0 4.9 1.1 7.0 2.8 1.0 1.0 0.68 YOR120W 3.0 1.2 3.6 2.4 1.5 3.9 1.3 2.6 1.06 YAL023C 1.7 1.2 2.3 0.4 2.5 0.4 1.0 0.7 1.49 YAL060W 2.4 0.8 2.2 0.9 0.9 3.2 1.1 1.8 2.39 YAL062W 1.2 1.0 2.1 0.8 1.1 1.3 1.0 0.8 0.86 YBR006W 1.9 1.1 2.2 1.1 1.1 3.0 1.2 1.8 0.62 YBR056W 1.8 1.4 3.0 1.0 0.7 2.8 2.4 3.4 1.13 YBR149W 1.9 1.4 2.2 1.2 0.7 2.7 2.1 3.4 2.72 YBR284W 1.4 1.2 2.8 1.6 0.8 0.8 1.1 1.0 0.25 YCL018W 3.7 1.6 3.2 1.0 0.6 2.3 1.3 1.0 0.99 YCL040W 8.2 2.3 5.6 0.7 3.4 3.1 1.4 1.7 1.98 YDL010W 1.3 0.9 2.0 2.2 1.4 1.4 1.5 2.4 0.93 YDL024C 1.2 1.7 2.6 1.9 2.1 2.8 0.9 1.1 0.40 YDL095W 1.0 1.1 2.2 0.5 2.0 0.5 0.7 0.9 1.57 YDL245C 1.5 1.0 2.0 1.2 1.8 1.5 1.0 1.1 0.28 YDL246C 2.6 1.2 2.9 1.7 2.6 1.7 1.8 1.8 0.43 YDR001C 0.7 1.1 2.8 1.0 4.4 1.9 1.1 1.6 0.75 YDR058C 1.7 1.2 2.5 1.8 1.2 1.9 1.1 1.6 0.56 YDR072C 0.7 0.9 1.9 0.6 0.4 0.7 1.9 1.9 2.81 YDR127W 1.3 0.8 1.7 1.0 1.3 0.6 0.9 0.7 0.78 YDR261C 1.2 1.0 1.9 0.9 2.3 0.6 0.9 0.8 0.68 YDR272W 2.1 1.2 2.4 1.4 1.1 2.1 1.4 2.3 1.51 YDR497C 0.7 0.9 2.7 0.6 10.1 1.6 1.8 1.45 YDR516C 2.8 1.1 2.5 0.7 0.4 1.7 1.1 1.2 1.66 YER053C 2.4 1.7 4.1 1.3 1.1 2.8 1.2 2.3 1.83 YER096W 1.1 0.9 2.3 3.1 1.4 2.0 1.0 1.2 0.22 YER178W 2.5 1.3 2.4 0.9 1.8 1.0 1.1 0.9 2.18 YFL030W 5.4 1.2 2.2 0.8 1.1 0.6 1.0 0.8 0.50 YFL031W 1.2 1.0 2.6 0.4 2.7 0.9 1.2 1.1 3.16 YFR047C 2.3 1.7 2.7 1.9 0.6 3.6 1.5 1.6 1.57 YGL248W 1.0 0.8 2.0 1.3 1.8 2.9 1.1 1.2 0.22 YGR037C 1.4 1.5 2.7 1.5 1.5 2.6 1.4 2.0 3.40 YGR055W 1.5 0.9 1.9 1.2 2.1 0.6 0.7 0.7 1.42 YGR194C 0.7 0.8 2.2 1.0 0.6 2.6 1.1 2.0 0.63 YGR256W 2.7 1.5 3.9 1.1 2.7 5.3 1.1 0.8 0.94 YHR111W 1.9 0.9 2.2 1.7 1.1 1.3 1.1 1.2 0.44 YHR174W 1.4 1.5 3.6 0.6 2.0 1.1 1.0 1.2 7.34 YHR176W 1.2 1.2 1.9 1.3 1.5 1.8 1.4 1.6 0.27 YIL045W 1.2 1.5 2.0 1.6 0.6 2.9 1.1 1.8 0.37 YIL107C 0.9 1.1 1.9 1.6 1.0 2.7 1.2 2.0 0.58 YIL155C 1.3 1.4 2.0 1.3 1.4 3.8 1.1 1.4 0.51 YIR034C 3.0 1.4 2.6 1.2 1.9 1.3 1.0 1.0 0.92 YIR036C 2.8 1.2 1.9 1.2 1.1 4.0 1.5 1.3 0.64 YJL031C 1.9 1.3 2.6 3.0 2.0 1.9 1.2 1.9 1.02 YJL068C 3.2 1.7 2.7 1.5 0.5 2.6 1.4 1.5 0.95 YJL099W 0.9 1.0 2.4 1.8 1.4 1.7 1.2 1.6 0.55 YJL172W 1.4 1.1 3.1 0.9 1.2 0.5 1.8 1.8 0.62 YJL219W 2.3 1.1 4.0 1.1 2.6 1.4 1.6 1.2 0.91 YJR137C 2.0 1.4 2.1 1.2 1.0 1.3 0.9 0.8 0.46 YKL035W 2.1 1.0 2.0 0.6 1.0 1.5 1.0 1.9 2.54 YKL091C 1.7 1.3 2.0 1.5 1.1 4.6 1.4 2.0 0.83 YKL104C 2.2 1.6 2.2 0.8 3.3 0.6 1.0 1.1 1.25 YKL152C 1.7 1.5 2.7 1.0 1.8 2.0 1.1 1.7 3.28 YKL213C 1.3 0.9 2.1 0.9 1.1 1.5 1.4 1.6 0.77 YKL215C 0.5 1.0 2.6 1.0 0.9 0.8 0.8 0.9 0.38 YLL058W 2.0 1.0 2.3 0.8 1.9 1.1 1.4 1.3 0.39 YLR299W 1.7 1.0 2.9 1.3 1.5 0.9 1.3 1.4 0.57 YLR348C 1.3 0.9 1.9 1.0 2.4 1.1 1.1 1.0 0.64 YML054C 1.4 1.8 2.8 2.1 1.1 7.8 1.1 1.6 0.25 YML070W 1.5 1.3 3.3 1.3 0.9 2.6 1.2 1.3 1.03 YML100W 3.2 1.2 3.8 1.2 1.8 2.2 1.0 1.5 0.88 YMR008C 1.3 1.1 3.7 0.7 2.0 1.2 3.0 1.9 1.59 YMR020W 1.5 1.1 3.0 1.1 1.8 2.8 2.3 2.2 0.81 YMR105C 3.0 1.7 3.3 1.0 0.9 2.0 1.6 2.6 1.21 YMR271C 1.7 1.3 3.6 1.8 0.6 5.7 1.3 2.2 0.70 YNL012W 1.6 1.3 2.9 1.0 1.6 1.2 1.3 1.5 0.24 YNL045W 2.1 0.9 2.6 0.8 0.8 2.4 1.1 1.1 0.80 YNL104C 2.1 1.1 2.1 0.9 2.5 1.5 0.9 0.9 1.69 YNL231C 1.3 1.8 2.9 0.9 0.9 0.7 3.1 4.0 2.13 YNR019W 0.7 1.0 2.1 1.0 1.6 0.8 2.4 2.0 0.37 YNR033W 0.4 1.1 3.8 0.9 1.3 2.2 0.9 1.1 0.72 YNR059W 1.0 0.8 2.4 1.0 1.0 2.0 2.6 2.2 0.45 YOL126C 1.8 1.1 2.6 1.2 1.4 2.5 1.6 2.4 0.59 YOL153C 2.4 1.9 2.9 1.5 1.2 5.4 1.1 1.7 0.37 YOR099W 1.2 1.1 1.6 0.7 1.5 1.1 1.2 2.3 3.94 YOR130C 0.6 0.9 2.1 1.3 1.0 0.8 1.5 1.1 0.51 YOR336W 1.4 1.0 2.1 1.1 0.6 0.9 1.0 1.0 0.44 YOR347C 1.4 1.2 1.8 0.9 2.0 1.4 1.7 1.3 1.31 YPL017C 0.4 1.0 1.9 1.6 1.0 1.3 1.3 0.8 0.19 YPR026W 1.6 1.2 2.3 1.5 3.1 2.5 0.9 1.3 0.26 YAL012W 4.0 1.1 1.1 0.9 3.1 1.0 0.9 0.8 0.96 YBR029C 0.7 1.3 1.7 0.9 3.5 0.9 0.6 0.8 1.56 YBR222C 1.3 0.9 1.6 0.5 4.3 2.1 0.8 0.9 0.52 YCL009C 1.5 1.7 1.6 0.7 6.5 0.9 1.1 0.8 0.68 YCL064C 1.8 0.7 1.6 0.8 21.4 1.0 0.3 0.3 1.42 YCR098C 1.3 1.3 1.4 1.1 11.0 0.8 1.7 1.6 0.22 YDR502C 1.3 1.3 1.2 0.8 8.2 1.0 0.9 0.9 2.75 YER026C 0.9 1.7 1.9 1.1 4.0 1.4 1.7 3.2 4.48 YHR137W 0.6 0.6 0.6 0.8 2.8 0.4 0.8 1.3 1.40 YMR189W 8.2 0.6 0.9 1.6 5.6 0.9 1.0 0.8 0.88 YNL106C 0.9 0.8 0.9 1.1 3.3 1.2 1.1 0.9 0.37 YNL169C 0.8 1.0 1.7 0.9 3.4 0.8 1.1 1.3 1.05 YNL322C 0.6 0.7 0.8 1.2 3.7 0.9 0.9 1.0 0.75 YAL038W 1.0 1.2 1.8 0.5 3.1 0.9 1.0 1.0 7.02 YBR023C 0.9 0.8 0.5 0.8 2.8 0.7 0.7 0.9 0.93 YCR048W 1.2 0.9 1.3 0.9 3.1 1.1 1.2 0.8 0.29 YDR380W 0.4 0.4 0.4 0.6 2.4 0.2 0.8 0.8 1.04 YER069W 1.5 0.8 1.4 1.3 2.4 1.1 1.1 0.9 0.25 YGL022W 0.8 0.7 1.0 0.5 4.0 0.3 0.9 0.7 0.91 YGL126W 1.0 0.6 2.8 0.9 0.9 0.34 YGL209W 0.8 1.3 1.9 1.6 3.2 2.8 1.1 1.5 0.63 YGR282C 1.5 1.3 1.2 1.0 2.9 1.4 1.1 1.5 5.04 YIL154C 1.2 1.1 1.7 0.9 4.3 1.2 1.2 1.0 0.39 YJL088W 0.9 0.7 1.0 2.0 5.7 0.7 1.4 0.9 0.27 YJR148W 0.6 0.8 1.1 1.3 3.2 1.3 1.3 1.7 1.50 YLR180W 1.7 0.6 0.6 0.6 2.5 0.5 0.8 0.7 3.23 YLR273C 1.4 0.9 1.7 1.3 2.6 1.5 1.0 1.0 0.20 YLR300W 1.0 0.5 0.2 0.6 2.7 0.3 0.7 0.5 5.14 YLR307W 0.8 0.7 1.0 1.9 3.9 0.9 1.1 1.0 0.16 YMR296C 0.8 0.8 0.9 0.7 6.7 0.5 0.8 0.7 0.52 YOL058W 2.3 1.3 1.2 1.5 2.7 0.9 1.2 0.8 0.82 YBR183W 1.9 1.2 1.4 1.3 1.1 2.1 1.4 2.4 1.47 YDR019C 1.8 0.7 1.0 1.6 1.8 1.8 1.2 1.6 2.48 YIL167W 1.9 0.7 1.2 1.4 0.6 2.3 0.7 0.8 2.11 YKR039W 1.9 1.5 1.3 1.2 1.7 1.9 0.9 1.1 0.40 YNL037C 1.4 1.3 1.9 1.3 0.9 1.4 0.9 1.3 2.05 YNR002C 1.6 1.2 2.1 1.2 1.0 2.4 1.5 2.1 0.29 YOL143C 2.0 1.2 1.2 0.7 1.0 2.2 1.8 1.4 2.30 YOR136W 1.4 1.2 1.5 0.9 1.2 1.3 0.8 1.3 3.20 YAL044C 1.4 0.6 1.1 1.4 0.7 1.0 1.4 1.8 4.07 YAL054C 1.3 1.0 1.8 1.3 0.9 2.5 1.5 1.4 0.24 YAR071W 1.1 2.0 0.3 1.1 1.1 0.3 0.7 1.6 3.21 YBL001C 2.3 0.7 1.0 1.5 1.0 1.7 1.6 1.8 2.38 YBR014C 1.8 0.6 0.9 1.2 1.2 1.5 1.0 1.6 1.29 YBR035C 2.0 1.2 1.8 1.3 0.7 2.1 1.5 1.9 1.89 YBR068C 0.8 0.8 2.2 1.8 1.6 5.5 1.1 1.3 1.99 YBR111C 1.5 1.2 1.6 1.6 0.7 3.5 1.4 2.4 3.20 YCR037C 0.8 0.7 1.3 0.8 1.0 1.1 1.4 0.9 0.74 YDL022W 2.8 1.2 1.5 0.8 0.9 1.1 1.0 1.4 1.79 YDR009W 0.1 1.0 1.2 1.5 3.2 1.0 1.2 1.0 0.21 YDR410C 1.6 0.9 1.2 1.3 1.2 0.8 1.0 1.0 1.33 YDR487C 2.1 1.3 1.5 2.5 1.0 1.5 1.5 1.9 2.61 YEL011W 3.7 1.5 1.5 1.5 0.4 2.4 1.4 2.5 0.89 YFR015C 3.9 0.4 2.5 3.1 0.4 2.4 1.3 1.2 0.66 YGL001C 1.6 0.9 1.0 1.1 0.9 2.2 1.9 2.1 2.53 YGL104C 1.8 1.1 2.0 1.0 0.9 1.7 1.3 1.3 0.58 YGL154C 0.9 0.9 2.0 1.1 0.8 0.7 1.0 1.1 0.57 YGL253W 1.0 1.2 1.5 0.5 0.8 0.4 0.7 0.8 4.63 YGR060W 0.8 1.0 0.6 0.8 1.4 2.1 1.3 1.6 4.19 YHR037W 1.7 1.1 1.1 1.1 1.1 2.0 1.0 1.4 1.15 YHR092C 1.5 1.0 0.5 1.6 0.2 1.2 0.9 1.3 6.09 YHR190W 1.3 1.1 1.7 1.3 1.3 1.8 1.3 1.8 2.15 YIL033C 1.8 1.1 2.5 0.7 1.0 2.0 1.0 1.2 1.18 YIR035C 1.3 0.9 1.1 1.1 1.4 1.0 1.1 0.9 1.51 YJL132W 1.4 1.0 1.3 1.4 1.1 2.1 1.3 1.5 0.37 YJL196C 2.3 1.1 0.6 0.8 0.6 1.7 0.9 1.9 2.85 YJR142W 0.9 0.8 1.6 1.3 0.6 2.0 1.2 1.4 0.94 YKL067W 1.8 0.9 1.7 1.2 1.1 2.4 1.4 3.2 3.29 YLR142W 3.8 0.8 1.2 2.1 1.6 3.4 1.9 3.2 0.28 YML110C 1.7 1.1 1.8 1.4 1.3 2.3 1.1 1.6 2.01 YMR272C 0.8 1.2 1.2 0.8 1.1 1.5 1.3 1.4 1.66 YNL130C 1.5 0.9 1.9 1.0 2.5 0.7 0.7 1.2 1.18 YPR006C 2.4 1.1 1.8 1.2 0.7 1.6 1.8 2.1 0.46 YBR050C 1.1 1.0 1.3 1.3 0.5 1.7 1.5 1.8 0.41 YBR145W 1.1 1.0 2.0 2.2 1.2 3.6 1.7 2.0 2.17 YBR299W 2.4 1.2 0.7 1.4 0.6 3.9 1.0 1.1 0.32 YEL020C 1.3 0.8 1.2 1.0 1.4 2.1 1.2 1.3 0.31 YGL039W 1.1 1.3 1.5 0.9 1.5 1.5 0.6 1.0 1.09 YGL134W 1.1 0.9 0.7 1.1 0.5 1.7 0.9 1.3 0.53 YJR159W 2.2 1.5 2.1 2.0 2.3 5.2 1.7 2.3 0.30 YOL157C 1.2 1.2 1.4 1.2 1.1 3.5 1.4 1.3 0.41 YOR344C 0.6 1.3 1.8 0.6 0.7 0.6 1.3 1.3 2.11 YPL265W 1.8 0.9 1.1 1.1 1.2 2.0 0.5 0.4 1.42 YBR126C 1.1 1.3 2.1 0.7 1.0 1.7 1.5 1.3 1.96 YCR005C 2.1 0.5 0.7 0.8 0.7 0.7 1.6 1.7 2.38 YDR452W 1.5 0.9 1.4 1.2 1.3 1.3 1.9 2.2 1.54 YGR019W 1.1 1.2 2.1 1.3 2.2 2.4 1.3 2.0 0.79 YGR255C 2.0 1.3 2.5 0.9 1.0 1.1 1.1 1.1 0.81 YIL098C 1.4 0.8 1.3 1.9 0.7 2.0 1.2 1.6 0.75 YIL172C 1.0 1.4 2.0 1.3 1.4 2.8 1.1 1.2 0.42 YLR100W 0.9 1.1 1.6 1.1 0.6 1.9 1.5 2.1 1.88 YOR221C 1.1 0.8 1.0 1.1 1.0 1.4 0.9 1.2 0.39 YPL123C 1.9 1.0 2.2 1.6 1.4 2.6 1.6 3.2 0.71 YBR093C 3.1 2.0 0.2 1.3 2.7 0.4 0.8 1.9 3.33 YBR196C 2.3 1.0 1.4 0.5 1.9 1.1 0.8 1.0 6.60 YER023W 2.1 0.8 1.2 0.7 1.2 1.6 1.5 1.4 1.77 YFL055W 2.7 0.9 1.3 1.5 0.7 1.4 1.4 1.0 0.23 YIL124W 2.8 1.1 0.9 1.1 0.6 3.1 1.2 2.1 2.39 YMR318C 3.6 0.8 1.8 1.7 1.5 1.1 1.1 1.1 3.17 YBR067C 3.1 1.0 0.9 0.7 3.3 2.5 0.5 0.4 1.76 YBR115C 1.8 0.9 2.3 0.7 1.1 0.5 0.6 0.6 0.64 YDL131W 2.2 1.2 1.0 0.9 1.1 0.9 0.7 0.6 1.81 YDL168W 1.9 0.6 1.3 1.6 1.2 1.1 0.9 0.8 1.08 YDR216W 2.1 1.0 2.4 0.9 2.5 1.6 1.0 1.8 0.44 YDR253C 2.3 1.0 2.2 3.6 1.2 1.6 1.0 1.0 0.38 YDR513W 2.0 0.9 1.8 2.0 1.3 3.8 1.3 3.2 3.10 YER061C 2.2 0.7 0.9 1.0 0.8 1.8 1.2 1.2 0.84 YFL052W 2.3 0.8 1.0 1.6 0.4 1.0 1.1 0.9 0.32 YFL058W 2.4 1.2 1.2 1.0 1.7 0.7 1.1 0.9 0.40 YFR030W 2.4 2.4 4.1 1.3 1.7 1.6 1.3 0.9 0.30 YGL202W 2.4 0.9 1.1 0.8 2.2 0.6 1.3 0.9 1.70 YGR070W 1.8 0.6 1.4 1.0 2.6 2.3 1.2 1.3 0.40 YHL036W 2.3 1.2 1.5 1.2 0.9 1.1 1.0 1.0 0.60 YHR104W 2.6 1.0 1.2 1.5 1.6 1.3 1.9 1.9 1.57 YJL045W 2.3 1.1 1.6 1.2 3.4 2.4 0.9 0.9 0.42 YJL060W 1.6 1.5 2.1 1.7 1.4 1.5 1.2 1.1 0.95 YJL155C 2.4 1.0 6.6 1.2 1.2 2.3 1.8 3.1 0.60 YJR109C 1.5 1.4 3.1 0.9 1.3 0.5 1.1 0.6 0.84 YJR156C 3.0 1.1 1.6 2.4 3.0 2.3 0.8 1.1 0.24 YLR092W 3.1 1.0 1.8 1.4 0.9 1.2 1.0 1.1 0.24 YMR081C 2.5 1.1 0.7 1.8 0.2 3.0 1.9 3.0 0.62 YMR250W 4.3 1.2 2.6 1.1 2.0 5.0 1.2 3.0 0.84 YNL277W 3.2 1.3 1.8 1.5 0.6 1.3 0.9 0.7 0.27 YOR184W 2.7 0.7 0.6 0.7 1.0 0.9 1.2 1.2 3.19 YPR160W 4.4 2.1 2.2 1.1 1.4 5.3 1.0 2.9 1.42 YDL182W 2.0 1.4 1.5 0.8 0.7 1.1 0.6 0.6 2.31 YBR291C 1.1 0.9 1.0 1.7 0.5 1.5 0.9 1.3 1.19 YIL094C 1.8 1.0 0.7 1.0 0.5 0.9 0.9 1.0 2.26 YNR050C 1.5 1.0 1.1 0.6 0.3 1.4 0.6 0.7 2.13 YDL244W 1.2 1.2 2.0 2.0 2.9 1.5 1.1 1.0 0.25 YDR054C 1.9 1.0 2.5 1.1 1.6 1.4 0.8 1.4 1.18 YDR353W 1.4 0.8 0.7 1.6 1.3 1.0 0.9 1.3 3.20 YEL070W 1.1 1.1 1.1 2.1 3.2 1.9 0.9 1.0 0.27 YIL168W 1.9 0.8 0.9 1.5 1.2 1.2 1.0 1.1 0.39 YJL221C 0.8 1.1 1.4 1.1 1.1 3.3 1.1 1.4 0.41 YJR095W 0.6 0.7 0.8 1.3 0.8 0.8 1.3 0.9 0.23 YKL085W 1.8 0.8 1.5 1.0 0.5 1.7 0.9 1.3 2.16 YKL188C 1.1 1.2 1.2 2.1 1.4 2.7 1.1 1.5 0.27 YKL217W 1.6 0.8 1.2 1.2 2.2 3.0 1.7 3.3 0.29 YKR061W 1.1 0.9 0.9 1.6 0.9 0.8 1.5 1.6 0.70 YLR174W 1.3 1.3 1.8 1.7 0.8 4.6 0.9 1.2 0.41 YLR260W 0.6 0.8 1.9 1.2 1.0 1.0 1.1 1.2 0.44 YNL009W 1.3 0.9 1.3 1.3 2.7 3.3 1.2 2.3 0.45 YNL117W 1.4 0.7 1.3 2.0 2.6 1.6 1.1 0.9 0.24 YNL183C 1.3 1.1 2.3 1.1 1.1 1.2 0.8 1.0 0.47 YNR073C 2.2 1.1 1.2 2.3 1.7 1.6 1.0 0.9 0.18 YPL161C 1.0 1.0 1.2 1.1 0.8 1.4 1.3 1.3 0.41 YAL061W 4.1 1.1 1.4 0.7 0.6 1.1 1.4 1.2 0.88 YAL067C 1.2 1.0 1.1 1.3 2.4 1.6 1.0 1.0 0.33 YBL033C 1.1 0.9 1.8 1.4 1.0 1.2 1.2 1.0 0.53 YBL086C 1.3 0.5 0.9 0.8 0.5 1.4 0.9 1.0 0.43 YBR117C 0.4 0.8 2.1 0.9 1.0 12.0 0.7 0.7 0.49 YBR213W 0.5 1.2 1.4 1.3 1.7 0.8 0.9 0.9 0.23 YCR036W 1.0 1.3 1.8 1.5 1.7 1.6 1.6 1.7 1.35 YDL132W 1.3 0.7 2.0 0.9 1.7 1.0 0.9 1.1 0.74 YER014W 0.9 1.1 1.5 1.2 2.3 0.8 1.0 0.9 0.43 YER042W 1.8 1.1 1.4 5.2 1.0 1.9 0.7 1.1 1.80 YER090W 1.8 1.3 1.2 1.2 1.5 0.8 1.1 0.9 0.97 YGL026C 3.4 1.3 1.8 0.9 2.4 0.7 1.5 0.8 0.87 YGL252C 0.9 0.9 1.2 1.0 1.3 1.2 1.0 1.3 0.91 YGL254W 1.1 1.2 2.4 1.3 1.1 1.4 0.8 1.2 0.53 YGR276C 0.9 1.0 1.8 1.0 0.8 1.3 0.9 1.1 0.97 YHR106W 1.4 0.7 1.0 1.2 0.9 2.4 1.3 1.1 1.73 YIL046W 1.2 1.0 1.7 1.1 1.3 1.8 9.0 5.8 0.68 YJL071W 1.3 1.1 1.0 1.0 1.5 1.2 0.9 0.9 0.41 YJR139C 1.5 1.0 1.5 1.4 0.7 1.2 1.0 1.3 4.47 YKR069W 2.0 1.4 1.4 1.7 1.1 1.8 1.0 1.0 0.25 YLL061W 1.7 0.7 0.9 1.3 1.4 1.0 0.6 0.7 0.33 YLR070C 0.4 0.7 2.0 1.3 0.5 2.1 1.0 0.9 0.31 YLR099C 1.2 0.9 0.8 0.7 0.9 0.7 0.7 0.5 0.92 YLR157C 1.9 1.2 1.8 1.1 1.1 2.1 1.6 2.1 1.70 YLR160C 1.6 1.2 2.0 1.2 1.0 2.0 1.6 2.2 1.59 YLR164W 3.2 0.7 1.0 1.5 0.7 11.0 1.5 1.2 0.31 YML042W 2.5 1.0 1.2 1.4 1.7 4.8 1.0 0.9 0.29 YOL049W 1.8 0.8 0.9 0.9 0.7 1.3 1.0 1.3 1.61 YOL064C 1.0 0.9 2.0 0.9 1.0 1.7 1.2 1.3 1.32 YOR377W 1.2 0.9 1.3 0.9 1.2 1.3 1.1 1.1 0.46 YPL031C 1.4 0.8 1.6 0.9 0.7 2.0 1.4 1.2 0.49 YPL113C 1.5 1.1 1.7 1.6 0.9 2.5 1.2 1.7 0.28 YPL274W 2.0 0.5 0.6 0.9 1.5 1.1 0.7 0.6 0.41 YPR048W 1.0 0.8 0.6 1.2 0.6 0.8 0.7 0.8 0.75 YBR001C 1.0 1.0 2.0 1.2 1.8 1.4 1.0 1.6 0.61 YBR018C 5.8 1.0 1.0 2.4 1.3 6.2 0.8 0.9 0.20 YBR204C 2.2 1.0 1.7 1.4 1.2 2.3 1.1 1.5 0.84 YBR241C 1.4 1.4 1.4 0.9 1.6 0.7 1.0 1.2 1.25 YCR105W 2.3 0.9 1.9 1.9 3.1 1.3 1.3 1.1 0.36 YDR287W 1.5 1.1 1.5 1.2 1.6 2.7 1.5 1.3 0.52 YDR294C 1.2 1.1 1.6 1.0 2.0 1.7 0.9 1.1 1.02 YER052C 1.1 0.9 2.1 0.7 1.2 0.2 0.8 0.4 1.54 YFL021W 1.3 0.9 1.5 1.1 1.3 1.0 0.8 0.5 0.40 YGL040C 0.9 0.6 1.6 1.3 0.7 1.5 0.7 1.0 1.77 YGL125W 1.6 1.0 1.4 1.0 1.9 1.2 1.2 1.1 0.27 YGR007W 0.9 0.8 1.4 1.8 1.9 1.3 1.1 1.4 0.74 YGR155W 1.3 1.0 1.4 0.7 0.5 1.0 0.5 0.6 4.15 YIL099W 0.9 0.9 1.4 1.6 5.5 1.2 1.0 1.1 0.18 YIL170W 1.7 0.7 1.9 1.1 2.3 1.8 1.6 1.5 0.48 YIR031C 1.2 0.8 1.0 1.2 0.8 0.7 0.9 0.8 0.44 YIR032C 1.4 1.0 1.4 1.6 0.6 1.6 0.9 1.1 0.40 YJL128C 0.6 1.0 1.7 0.8 1.2 0.9 1.0 1.0 0.42 YJR090C 0.4 0.8 2.2 1.0 1.6 0.8 1.1 1.0 0.60 YJR103W 1.1 0.6 0.7 0.7 3.2 2.3 0.9 1.0 0.74 YJR153W 2.0 0.7 1.3 1.7 2.9 1.6 0.8 1.0 0.18 YKL192C 1.1 1.2 1.7 1.5 1.2 2.1 1.0 0.8 1.57 YLR025W 1.1 0.9 1.0 1.7 1.5 2.2 1.2 1.3 1.15 YML051W 1.4 0.7 1.2 1.1 1.4 1.1 0.7 1.0 0.57 YML099C 1.6 1.1 1.3 0.9 1.0 1.6 0.7 0.8 0.48 YMR056C 1.6 0.9 0.9 1.1 0.7 2.4 1.0 1.1 0.72 YNL257C 1.0 1.1 1.7 0.8 1.0 1.4 0.9 1.3 0.63 YNL264C 1.0 1.1 1.5 1.2 1.1 1.3 0.7 1.1 0.48 YNR071C 1.3 0.6 1.7 1.1 1.8 1.0 1.0 0.9 0.16 YOL065C 1.0 0.8 1.3 1.1 0.7 2.6 1.1 1.5 0.43 YOL067C 1.3 0.7 1.7 0.7 1.2 1.1 1.4 0.9 0.55 YPL147W 1.3 0.9 1.5 1.0 2.4 2.5 1.5 3.6 0.33 YDR043C 1.3 0.9 0.7 1.8 1.2 1.4 1.9 1.2 0.66 YGR180C 1.0 0.9 0.9 0.9 1.3 1.2 1.0 1.9 3.90 YJL026W 1.3 1.0 1.2 1.0 1.1 1.6 1.4 2.1 3.74 YGR087C 0.8 1.2 1.2 0.7 3.5 0.6 1.0 0.6 1.88 YGL256W 1.0 0.9 0.8 0.9 1.0 0.7 0.7 0.8 0.90 YAL039C 1.1 1.4 1.6 1.2 3.3 2.2 1.4 1.1 0.39 YJR107W 1.3 1.1 1.7 1.4 1.1 1.1 1.4 1.3 0.41 YNL142W 0.9 1.2 0.9 0.8 0.3 1.0 1.0 0.9 0.44 YDL210W 0.6 0.8 1.2 1.1 1.9 0.9 1.1 0.9 0.20 YGL055W 0.9 1.3 0.2 0.7 0.5 3.0 1.0 1.5 5.60 YCL025C 1.0 1.1 0.5 0.7 0.8 0.6 0.6 0.6 1.98 YBR132C 1.9 1.0 1.4 1.1 1.5 1.3 1.1 1.3 0.43 YHL018W 1.2 0.7 0.8 1.0 0.9 0.9 1.0 0.9 0.37 YPL038W 1.1 0.6 0.6 0.9 0.6 0.8 0.9 0.9 0.64 YKR053C 0.5 0.7 0.7 1.3 0.3 0.9 2.8 2.4 0.35 YNL256W 0.6 0.6 1.3 0.7 0.9 0.4 0.6 0.6 1.09 YLR377C 0.6 0.6 1.2 2.9 0.8 2.7 0.9 1.4 0.14 YBR253W 1.1 1.0 0.8 1.2 0.9 1.3 1.3 1.1 0.96 YBL030C 1.1 0.9 0.5 0.8 1.8 1.0 1.0 1.1 3.12 YBR221C 1.2 1.3 1.7 0.8 1.1 1.5 0.9 1.0 3.62 YDR342C 2.9 1.0 0.6 0.9 0.5 2.4 1.0 2.2 5.23 YDR343C 2.3 1.0 0.8 0.8 0.5 2.8 1.1 2.3 5.81 YEL034W 1.1 0.9 0.8 0.9 0.8 0.9 0.9 0.9 5.44 YHR094C 0.6 0.9 0.7 0.6 2.7 0.9 1.4 1.4 4.82 YIL162W 2.8 2.0 1.0 1.0 1.5 1.7 0.9 1.4 1.22 YJR105W 1.0 0.8 0.8 0.5 1.2 0.7 1.1 0.9 3.75 YLR134W 1.1 1.2 1.5 0.6 1.7 0.5 0.6 0.8 3.47 YLR258W 1.2 0.9 1.4 1.2 0.6 1.7 1.0 2.0 1.36 YML058W 3.3 0.9 1.4 1.1 2.5 1.3 1.3 1.5 2.14 YMR083W 1.6 0.7 0.9 0.8 1.3 1.3 0.9 1.1 2.52 YOR178C 4.1 1.7 1.0 1.0 1.1 1.7 1.0 1.5 0.56 YPL028W 1.2 1.4 0.9 0.8 0.6 2.2 1.4 1.8 4.35 YPR113W 2.0 0.7 0.7 1.3 1.0 2.3 1.2 1.9 2.85 YPR183W 2.5 1.2 1.6 0.7 0.9 0.8 1.2 1.0 1.17 YBR011C 1.7 1.1 1.5 0.9 2.1 1.7 0.8 1.1 3.68 YCR034W 0.8 0.5 0.2 0.6 0.9 0.3 0.9 0.7 3.77 YDR050C 2.0 1.4 2.0 1.2 1.9 1.3 1.1 2.3 6.26 YDR178W 2.0 1.3 1.5 1.5 0.7 3.0 1.2 2.3 2.27 YDR284C 1.3 0.9 1.2 1.3 0.9 1.7 1.5 1.5 1.44 YDR345C 1.5 1.4 1.2 0.8 0.8 1.0 1.3 1.8 5.65 YDR400W 1.3 0.4 0.7 0.9 0.8 1.1 1.1 0.8 0.56 YEL063C 0.8 1.1 1.1 0.8 1.3 1.0 0.7 0.7 1.12 YER081W 1.1 1.0 0.6 1.6 0.5 0.8 1.1 1.7 2.31 YER120W 1.1 1.3 1.0 0.9 1.5 1.0 1.2 1.0 1.52 YFL011W 2.1 0.9 0.8 0.8 1.7 1.2 0.8 1.0 1.25 YGL012W 0.6 0.6 0.3 0.8 0.6 1.2 0.9 1.1 4.88 YGR191W 1.6 0.7 1.0 0.7 1.5 0.7 0.8 0.8 1.58 YGR204W 2.1 1.0 1.3 0.5 1.6 0.6 1.0 0.7 1.49 YHR025W 2.1 0.9 0.7 0.6 2.1 0.5 1.0 0.6 0.68 YHR123W 1.2 0.7 1.5 0.8 2.3 0.5 1.1 1.0 0.85 YJL121C 1.1 0.6 0.7 0.9 1.0 0.6 1.1 1.0 1.00 YJR077C 1.6 1.0 0.9 0.7 1.5 0.7 1.0 0.8 1.79 YJR143C 1.3 0.6 0.3 0.6 1.1 0.5 0.7 0.8 3.24 YKL060C 2.1 1.3 1.2 0.8 1.6 1.5 1.2 1.7 6.01 YKL148C 1.5 0.8 0.8 0.8 0.6 1.1 0.8 1.0 0.54 YKL157W 1.5 1.0 2.3 0.8 1.2 1.7 1.2 1.5 1.22 YLR044C 1.1 1.4 1.7 0.5 2.2 0.6 0.9 0.9 5.16 YLR056W 0.8 0.9 0.2 0.7 0.9 2.1 1.1 1.1 3.61 YLR058C 2.6 0.4 0.3 0.7 1.5 0.4 0.8 0.8 2.71 YLR081W 2.6 1.0 0.6 1.0 0.7 1.2 0.7 0.9 1.46 YLR089C 1.7 0.6 1.0 0.7 1.7 1.4 1.2 1.3 1.27 YLR284C 1.5 0.6 0.8 1.3 1.0 4.5 2.9 8.1 0.84 YLR304C 1.6 1.0 0.5 0.7 1.6 1.8 0.5 0.7 2.39 YLR354C 1.7 1.2 1.0 0.9 2.4 1.3 1.0 1.5 4.53 YLR372W 0.9 0.6 0.1 0.6 0.7 0.2 0.5 0.6 4.46 YML022W 1.2 0.6 0.2 0.9 0.6 0.6 0.5 0.7 4.93 YMR011W 1.5 0.8 0.4 0.6 0.6 1.2 1.3 1.6 4.95 YMR015C 1.0 0.9 0.4 0.8 1.2 1.5 1.0 1.0 2.51 YMR205C 1.0 1.1 1.3 0.5 0.9 0.9 0.6 0.5 4.75 YMR261C 0.8 0.9 1.6 0.6 0.8 1.6 0.7 1.1 0.78 YMR323W 2.5 1.2 1.8 1.2 37.3 0.6 1.1 0.6 1.04 YOL086C 2.6 1.3 1.7 0.6 1.6 1.4 1.1 1.3 4.19 YOL156W 1.1 0.9 1.7 0.9 1.9 0.9 0.9 0.9 0.53 YOR002W 1.2 0.5 0.6 0.9 1.5 0.8 0.9 1.1 1.49 YOR085W 1.1 0.8 1.0 0.7 1.8 0.8 0.9 0.9 1.86 YOR108W 1.4 0.7 1.3 0.9 0.7 1.0 1.1 1.1 1.07 YOR128C 0.8 0.5 0.4 0.7 1.6 0.5 1.2 1.2 2.14 YOR142W 1.5 0.8 1.4 0.8 1.1 0.8 0.9 1.0 1.31 YOR176W 1.4 1.3 1.5 0.8 0.8 1.4 1.2 2.1 1.23 YPL057C 1.6 1.0 1.3 0.7 1.1 2.5 2.2 2.0 2.08 YPL135W 1.3 1.1 1.2 1.1 1.5 1.2 1.5 1.7 1.50 YCR010C 1.1 0.8 1.0 1.2 1.2 2.8 1.9 1.5 0.26 YBR003W 1.3 0.8 1.2 0.8 0.7 2.0 1.1 1.3 1.06 YBR020W 1.0 0.8 1.1 1.0 1.3 0.7 0.8 0.9 0.27 YDR123C 0.6 0.5 0.9 0.7 1.2 0.8 1.3 1.0 0.30 YDR277C 1.2 0.9 1.2 1.3 0.4 2.3 1.2 1.7 0.89 YDR408C 1.7 0.6 0.5 0.9 1.0 1.0 1.1 1.1 2.16 YDR483W 1.4 0.8 1.3 0.8 1.5 1.2 1.2 1.4 3.24 YGL115W 1.0 0.9 0.7 1.2 0.7 1.7 0.8 1.2 2.46 YGR096W 0.8 0.8 1.1 1.2 0.9 0.8 0.8 1.0 0.49 YGR288W 1.3 0.9 1.3 1.1 0.8 1.7 1.2 1.3 0.41 YHR210C 1.5 0.5 0.4 1.0 0.5 1.5 1.4 1.2 0.33 YIL006W 1.0 0.9 0.8 1.0 1.5 1.7 0.8 0.9 0.28 YKR034W 0.0 0.7 1.2 1.1 1.7 0.6 0.8 1.0 0.26 YLR006C 1.5 0.7 0.8 1.0 0.9 0.8 1.6 1.0 0.40 YNL025C 1.1 0.8 1.3 1.2 1.4 2.9 0.7 1.3 0.37 YOL116W 1.0 0.6 0.8 0.9 0.7 1.9 1.1 1.4 0.47 YOR103C 1.0 1.2 0.8 1.2 1.4 1.3 1.1 1.5 2.84 YOR251C 1.0 0.9 1.0 1.1 0.6 1.2 0.9 1.3 1.34 YOR348C 1.1 0.7 1.1 1.2 1.6 1.7 0.9 0.9 0.18 YPL148C 3.5 0.7 0.6 1.6 0.6 1.6 1.0 1.1 0.48 YGL205W 0.4 1.1 1.0 1.0 2.0 4.1 3.9 9.1 0.24 YNL192W 1.1 1.1 2.7 0.7 2.1 0.8 2.3 2.8 1.31 YOL108C 1.1 1.0 1.3 0.9 1.5 1.8 1.5 2.7 0.87 YPR165W 1.0 0.8 1.0 1.0 0.9 1.0 2.3 2.7 3.64 YDR073W 1.0 0.8 0.6 1.2 0.8 1.6 1.8 2.3 1.27 YER015W 1.0 0.9 0.8 1.1 0.8 3.0 1.6 2.6 0.41 YJL167W 1.2 1.3 0.9 0.9 1.6 1.4 1.4 2.1 2.94 YJL216C 1.1 1.0 1.1 1.1 1.2 1.5 1.2 2.0 0.25 YKR009C 1.2 1.0 1.8 1.0 1.0 4.6 1.9 2.5 0.27 YOR180C 0.6 0.8 0.9 1.0 1.1 2.4 0.9 2.3 0.55 YBR036C 1.5 1.0 1.9 0.8 1.5 1.6 2.1 1.8 2.05 YDR297W 1.4 1.0 0.8 0.9 1.4 1.4 1.9 1.9 1.73 YDR387C 2.0 0.9 1.3 0.9 1.4 2.7 1.2 1.1 0.86 YOL096C 1.2 1.2 1.4 1.4 1.0 2.3 1.2 1.2 0.64 YPR184W 3.6 1.4 2.5 1.3 1.5 3.1 1.0 1.7 0.37 YBR298C 1.5 1.1 0.8 0.9 0.2 2.1 0.9 0.8 0.88 YDL078C 1.7 0.8 1.0 0.8 0.5 2.2 1.1 2.0 1.65 YDL215C 0.8 0.8 1.5 1.0 1.1 2.2 1.1 1.6 0.91 YGL035C 1.3 0.9 1.1 1.1 1.0 2.3 0.9 1.2 0.61 YGR287C 1.5 1.1 1.7 1.1 2.3 3.0 1.0 1.1 0.38 YJL070C 1.3 1.0 1.8 1.3 3.5 2.2 1.1 1.2 0.34 YLR351C 1.1 0.9 0.9 1.4 1.2 2.0 1.3 1.8 1.75 YLR375W 1.6 0.9 1.6 0.9 1.3 2.2 1.0 1.0 1.05 YMR267W 1.0 0.8 0.7 1.0 0.9 2.6 0.9 1.3 0.94 YMR278W 1.1 1.0 2.5 0.8 1.8 2.5 1.0 1.5 0.62 YMR293C 0.4 0.9 0.8 1.3 0.7 2.2 0.8 1.0 0.37 YNR072W 1.4 1.0 1.5 1.0 1.8 2.1 1.3 1.0 0.26 YOR363C 1.2 0.9 1.3 0.9 1.1 2.1 1.3 1.8 0.40 -
TABLE 8 Detoxification protein genes yeast The level of expressed mRNA in the presence of chemical substance/ genes (1) (2) (3) (4) (5) (6) (7) (8) (9) (10) YDR453C 1.1 2.7 4.4 3.0 0.7 1.7 1.0 1.3 4.5 6.1 YLL060C 12.5 4.2 2.3 2.6 0.9 1.4 2.0 5.8 13.0 23.2 YBL064C 2.6 2.8 3.9 1.7 0.8 5.2 2.5 2.4 4.5 3.8 YBR008C 3.0 2.4 4.9 0.7 0.9 1.0 0.9 2.8 54.6 21.1 YOR153W 1.6 0.9 5.1 1.1 1.0 7.4 2.6 0.5 3.2 1.2 YHL047C 0.6 4.4 1.0 1.0 1.2 8.4 16.8 1.5 1.2 11.9 YCL035C 2.0 2.3 1.5 1.7 1.5 5.1 2.7 1.4 1.9 2.3 YGR197C 1.1 2.4 2.5 1.0 0.7 0.5 1.3 0.8 16.7 3.2 YHR055C 4.4 1.8 0.8 1.2 2.7 1.6 1.1 2.1 3.9 3.3 YNL239W 1.0 2.4 2.4 1.2 1.2 1.8 2.1 1.3 2.5 6.0 YNL241C 1.3 2.5 4.3 1.0 0.8 0.9 3.2 0.9 3.4 7.4 YBR293W 1.9 3.1 1.0 1.8 0.8 0.9 0.9 0.9 5.5 2.4 YDL100C 1.0 1.2 1.1 0.8 1.0 2.1 1.6 1.7 5.4 3.2 YER185W 2.0 3.1 2.1 7.0 1.6 1.2 1.1 1.0 2.9 1.2 YGL013C 0.9 1.2 0.8 0.7 1.1 2.3 0.9 1.4 3.0 1.5 YHR053C 3.5 2.1 0.7 1.1 2.9 1.3 1.2 2.2 4.5 2.9 YIR038C 1.3 3.5 4.6 2.0 0.7 2.5 2.0 1.3 4.6 4.5 YKL026C 2.7 2.0 1.2 4.9 1.0 1.8 2.5 1.8 7.5 3.0 YLL028W 0.6 0.9 4.6 0.5 0.9 1.7 1.0 0.7 1.2 2.3 YOR273C 0.7 1.0 1.7 1.0 1.1 0.4 0.4 0.6 0.6 0.5 YGR138C 1.1 1.6 1.0 1.2 0.8 0.8 0.7 1.0 0.5 1.0 YOR247W 1.7 0.6 3.6 1.4 0.6 0.2 0.5 0.7 0.1 0.4 YPL163C 0.6 0.7 1.4 0.9 0.6 0.6 0.4 0.5 0.1 0.4 YHL040C 1.6 4.4 1.5 0.4 1.1 7.3 4.0 1.5 1.1 11.3 YEL065W 0.3 3.8 1.2 0.4 1.4 2.3 4.3 0.9 0.1 4.9 YIR002C 0.8 1.1 0.5 0.6 1.2 2.2 1.3 1.2 1.7 1.4 YNL259C 1.6 4.5 1.1 1.2 1.1 3.9 3.8 1.5 1.6 2.1 YBR145W 1.5 0.7 2.8 0.9 1.1 11.5 58.8 1.0 0.1 1.1 YLR043C 1.4 1.4 2.0 1.8 2.0 1.4 2.6 1.1 2.8 2.5 YGR209C 1.6 3.1 3.5 1.5 1.9 1.9 1.7 1.6 2.4 6.3 YDL168W 2.3 2.0 2.1 0.9 1.2 1.4 1.1 1.7 8.2 4.7 YDR513W 2.2 2.5 2.3 2.6 0.9 2.1 1.6 1.6 4.6 3.1 YGR088W 1.3 1.2 7.7 2.4 1.0 1.3 0.8 0.8 1.5 3.2 YHR048W 2.5 1.4 1.4 1.7 1.0 0.8 0.8 1.9 4.5 2.7 YJL101C 2.1 1.9 2.1 1.2 1.4 1.0 1.0 1.3 3.1 3.6 YML116W 4.1 1.3 1.5 1.4 1.2 0.9 1.4 2.2 1.4 3.1 YMR038C 1.9 1.7 1.8 0.8 1.5 1.0 1.1 1.9 2.4 2.6 YBR244W 0.6 1.4 2.0 0.9 1.7 1.0 0.6 1.0 1.4 3.0 YCL069W 0.9 15.7 0.9 0.8 0.9 1.4 1.3 1.2 6.9 YKR105C 0.8 0.9 0.9 1.5 1.0 1.2 1.0 1.3 1.0 5.2 YOL158C 0.7 4.0 2.4 0.9 1.2 2.0 1.6 0.7 1.7 6.1 YDR256C 0.8 1.4 0.7 1.3 1.2 0.5 0.6 0.8 5.2 2.0 YGL254W 1.2 1.1 0.8 0.6 1.1 0.7 1.3 1.4 3.1 1.8 YKL064W 0.6 0.9 0.4 0.8 1.2 1.5 1.1 0.9 2.4 1.6 YLL057C 2.2 59.9 1.8 0.9 1.1 1.0 1.6 1.4 121.8 2.9 YPR200C 47.7 1.7 0.8 5.0 1.6 0.8 1.3 1.4 4.7 3.8 YJR104C 1.4 1.8 2.9 1.2 1.5 1.4 1.1 1.5 1.9 2.8 YKR106W 1.3 0.8 2.1 1.4 1.2 1.6 0.9 1.3 10.5 7.4 YOR031W 2.6 1.7 1.3 3.4 1.4 0.9 1.3 0.9 0.7 1.3 YHR008C 1.3 6.9 4.8 1.8 0.6 1.0 0.7 0.9 1.7 2.4 YML028W 1.0 2.2 4.4 1.3 1.6 1.2 0.8 0.8 0.8 1.8 YEL027W 1.2 0.6 3.4 1.1 1.0 1.1 0.8 0.9 0.9 1.1 YKR066C 0.9 1.4 5.5 0.7 1.0 0.9 0.5 0.7 0.7 2.4 YDR538W 0.9 1.1 2.4 1.2 1.0 1.0 1.2 1.0 0.3 0.8 YMR015C 0.7 0.7 1.9 0.9 1.7 1.3 0.4 0.7 0.1 0.3 YOR251C 1.1 1.0 1.3 1.8 0.8 0.9 1.0 1.1 0.8 0.8 YLR046C 0.7 1.7 0.9 0.8 1.0 3.8 1.5 0.5 1.0 1.4 YGR224W 0.9 1.2 1.2 1.2 1.4 0.8 0.4 0.6 0.9 0.9 YFL050C 0.7 1.0 1.1 2.2 1.0 0.9 0.8 0.9 0.5 1.6 YCR083W 1.1 2.8 1.5 1.8 1.6 2.4 1.8 1.5 1.8 1.8 yeast The level of expressed mRNA in the absence of chemical substance genes (11) (12) (13) (14) (15) (16) (17) (18) Intensity YDR453C 2.3 0.9 1.4 3.8 2.3 5.6 1.0 1.5 1.53 YLL060C 14.1 1.1 1.8 10.6 1.5 3.6 1.9 2.3 0.57 YBL064C 2.9 1.7 4.1 5.0 1.3 5.0 1.2 2.3 1.67 YBR008C 9.4 0.8 2.0 4.1 0.8 3.1 2.0 1.2 0.37 YOR153W 1.0 4.0 11.8 0.3 3.6 1.6 2.5 3.1 1.91 YHL047C 1.0 2.6 3.8 0.5 1.1 2.3 1.2 1.2 0.74 YCL035C 2.1 1.5 2.8 2.5 1.9 5.5 2.6 4.2 1.74 YGR197C 1.1 1.2 2.4 1.5 1.0 1.5 1.7 1.9 0.37 YHR055C 1.8 1.2 3.0 1.5 0.5 0.8 0.9 0.6 3.96 YNL239W 1.9 1.5 3.6 1.3 1.7 1.5 1.1 1.4 0.68 YNL241C 3.0 2.0 4.9 1.1 7.0 2.8 1.0 1.0 0.68 YBR293W 1.1 1.0 3.0 1.4 3.1 1.6 1.0 0.9 0.94 YDL100C 2.8 1.5 2.5 1.4 1.0 1.3 1.2 1.4 2.60 YER185W 1.6 1.1 2.1 1.6 1.7 0.6 2.6 1.1 0.26 YGL013C 0.9 1.0 2.3 0.8 1.0 0.9 1.1 1.0 0.43 YHR053C 1.4 1.1 1.9 1.5 0.3 0.7 1.0 0.5 3.99 YIR038C 3.4 1.1 2.5 2.5 1.2 6.0 2.8 2.0 1.11 YKL026C 3.0 1.0 2.3 1.8 0.8 6.6 1.6 3.3 0.61 YLL028W 0.7 1.3 4.1 0.7 3.1 0.6 1.2 1.2 1.02 YOR273C 1.5 0.8 2.6 0.5 0.8 0.6 3.2 3.1 1.20 YGR138C 0.7 0.6 0.6 0.9 4.5 0.7 0.7 0.7 1.24 YOR247W 2.9 0.6 0.3 0.4 7.3 0.2 1.2 0.9 2.23 YPL163C 0.5 0.9 0.4 0.6 5.3 0.6 1.4 1.4 1.05 YHL040C 1.7 2.0 2.0 1.1 3.4 1.0 1.4 1.0 0.69 YEL065W 0.6 1.7 0.8 0.4 2.2 2.6 0.7 0.6 2.10 YIR002C 0.8 1.3 1.2 1.1 1.1 1.4 1.1 1.2 0.58 YNL259C 1.6 0.7 1.1 1.4 0.7 1.7 2.6 2.4 1.22 YBR145W 1.1 1.0 2.0 2.2 1.2 3.6 1.7 2.0 2.17 YLR043C 1.4 0.8 2.0 2.1 0.5 1.8 1.5 2.2 2.12 YGR209C 3.1 0.9 1.4 5.0 1.3 1.9 1.3 2.4 3.17 YDL168W 1.9 0.6 1.3 1.6 1.2 1.1 0.9 0.8 1.08 YDR513W 2.0 0.9 1.8 2.0 1.3 3.8 1.3 3.2 3.10 YGR088W 3.9 1.1 1.2 1.3 0.7 5.6 0.9 2.0 0.75 YHR048W 2.0 0.9 1.1 1.7 0.9 1.4 0.7 0.9 0.26 YJL101C 2.7 0.7 1.0 1.0 0.5 1.3 0.9 1.0 1.13 YML116W 4.3 0.5 0.8 2.0 1.9 1.0 1.0 1.0 0.94 YMR038C 2.7 0.9 1.7 1.1 0.6 1.5 1.2 1.3 1.76 YBR244W 1.5 0.5 0.4 3.7 0.4 0.7 1.2 1.2 3.42 YCL069W 1.0 0.9 0.8 1.3 1.4 0.9 1.0 1.0 0.25 YKR105C 0.0 0.8 2.5 1.2 1.5 0.7 0.8 1.0 0.26 YOL158C 0.7 0.9 1.4 1.0 0.9 1.2 1.4 1.7 1.30 YDR256C 1.4 0.8 1.1 1.6 1.0 4.3 1.0 2.0 0.30 YGL254W 1.1 1.2 2.4 1.3 1.1 1.4 0.8 1.2 0.53 YKL064W 0.7 0.7 1.6 1.1 0.7 1.4 1.3 1.3 0.60 YLL057C 1.3 0.7 1.4 1.1 1.4 0.9 3.0 1.3 0.19 YPR200C 2.0 0.4 0.6 2.0 0.7 1.2 1.1 1.0 0.27 YJR104C 2.6 0.9 0.9 2.0 1.3 2.9 0.9 1.1 3.50 YKR106W 1.8 0.8 1.4 1.7 2.8 0.9 0.8 0.16 YOR031W 1.2 0.8 1.8 1.5 1.4 6.2 1.7 2.4 0.52 YHR008C 2.1 0.7 1.2 1.6 1.7 2.2 0.9 1.0 1.04 YML028W 1.0 1.6 1.6 2.0 2.2 1.3 1.1 1.5 4.85 YEL027W 0.9 0.9 0.7 1.4 1.5 1.6 1.0 1.4 4.75 YKR066C 1.3 0.9 0.6 1.5 0.6 1.3 0.9 1.1 1.25 YDR538W 0.9 0.7 0.7 0.9 1.0 0.9 1.0 0.9 0.53 YMR015C 1.0 0.9 0.4 0.8 1.2 1.5 1.0 1.0 2.51 YOR251C 1.0 0.9 1.0 1.1 0.6 1.2 0.9 1.3 1.34 YLR046C 0.9 0.8 1.2 1.3 0.8 1.3 5.2 5.4 0.86 YGR224W 0.8 0.6 0.8 0.9 1.1 1.0 2.8 1.3 0.27 YFL050C 1.2 0.9 1.2 1.0 1.4 2.3 0.8 1.0 0.36 YCR083W 1.8 1.1 1.8 2.4 1.0 3.1 1.3 1.3 0.98 -
TABLE 9 Genes belonging to other category yeast The level of expressed mRNA in the presence of chemical substance/ genes (1) (2) (3) (4) (5) (6) (7) (8) (9) (10) YKR076W 5.0 2.6 3.5 2.2 1.0 4.7 4.9 6.2 43.4 43.1 YNL335W 1.2 0.7 1.5 2.3 1.5 1.6 1.3 1.7 1.6 5.3 YBR173C 1.1 2.4 3.4 1.6 0.7 1.3 1.6 1.2 6.0 5.1 YFL022C 0.8 0.9 1.5 0.6 0.7 0.9 0.3 0.8 0.5 0.5 YGL158W 1.1 2.8 1.9 12.9 1.0 0.4 1.3 1.3 −0.4 0.9 YHR139C 3.0 4.6 6.8 9.3 1.3 1.9 1.5 1.3 107.2 46.6 YGR213C 5.4 2.9 1.0 6.8 1.2 4.1 7.0 2.0 7.5 6.9 YKL165C 0.5 2.0 1.1 0.6 0.9 0.6 2.1 1.5 0.4 0.4 YBL005W-A 1.0 0.9 0.5 0.9 1.3 1.2 1.4 1.0 0.8 1.5 YBL041W 1.2 1.4 0.9 1.0 1.6 1.7 1.6 1.7 2.8 2.6 YBL078C 2.3 2.7 1.3 2.6 0.7 2.4 3.1 1.6 12.3 15.2 YCL020W 1.1 2.5 0.5 1.1 0.5 1.0 1.5 1.7 0.9 2.4 YDL007W 0.8 1.4 1.3 0.9 1.0 1.1 1.2 1.4 3.8 2.4 YDL097C 0.9 1.7 0.9 1.2 0.8 1.3 1.6 1.5 4.5 2.3 YDL126C 0.5 1.4 2.3 0.7 0.9 1.2 1.5 0.8 2.7 2.0 YER012W 1.4 1.2 1.2 1.0 1.9 2.4 2.4 1.8 6.7 2.7 YFR010W 1.1 1.1 0.8 1.2 0.9 1.3 1.4 1.6 4.3 3.4 YFR024C 0.8 25.0 2.3 1.1 0.7 1.4 3.0 0.9 5.3 4.1 YGL048C 1.0 1.3 0.7 1.3 1.8 1.5 2.0 1.5 2.4 2.1 YGL141W 0.8 1.2 1.1 0.7 1.4 3.0 1.7 0.8 4.5 1.9 YGL180W 1.3 1.3 1.7 0.6 1.2 1.1 2.4 1.2 7.2 3.7 YGR048W 0.7 2.7 1.4 1.3 1.0 1.0 1.9 1.4 4.4 3.1 YGR135W 1.0 1.0 1.0 1.1 1.6 1.5 2.2 1.8 1.5 2.3 YGR201C 1.7 11.9 2.4 2.0 0.8 3.1 2.6 1.6 5.4 3.5 YHL030W 0.5 0.8 1.0 0.7 0.7 1.9 0.9 0.8 2.7 2.5 YHR166C 0.9 1.1 1.0 0.7 1.0 1.8 1.5 1.0 2.6 1.2 YJR069C 0.8 0.8 0.9 0.6 0.9 1.2 1.3 0.9 0.7 0.6 YKL073W 0.6 1.4 0.5 0.6 1.2 0.5 2.1 1.6 1.3 1.1 YKL103C 1.6 4.1 2.5 2.1 0.9 2.7 2.8 1.6 8.3 9.9 YLR080W 1.0 1.4 1.2 1.7 1.1 2.5 2.8 1.3 2.3 1.5 YLR107W 1.2 0.9 0.5 1.2 1.7 2.3 1.6 1.1 1.8 1.2 YLR121C 1.7 1.7 1.1 1.2 1.0 1.6 1.3 2.2 2.0 YLR336C 0.6 0.8 0.7 0.4 0.9 0.8 1.8 1.0 −0.3 0.5 YLR370C 1.1 1.0 1.1 1.4 1.4 4.1 2.1 0.8 1.5 1.9 YLR423C 1.2 1.2 0.7 1.9 1.5 1.2 3.8 2.0 1.2 1.0 YML092C 1.1 3.1 2.4 1.1 0.9 1.9 1.2 1.2 6.4 4.0 YML130C 1.5 2.7 5.3 1.2 0.9 0.6 2.9 2.7 7.8 4.2 YMR214W 0.8 3.8 1.0 1.4 0.8 0.9 1.0 1.1 2.1 1.0 YMR297W 0.7 2.0 3.6 1.9 0.6 1.8 1.2 0.8 1.9 1.0 YNL036W 2.0 1.9 3.2 1.0 1.6 1.1 2.0 2.1 6.6 5.0 YOL005C 1.4 1.4 1.1 0.8 1.6 1.1 1.1 1.0 0.9 1.0 YOR134W 2.0 3.6 1.0 9.5 0.9 1.4 1.1 1.5 1.5 8.2 YOR362C 1.0 1.7 1.0 0.8 1.7 1.4 1.6 1.4 4.3 3.0 YAR009C 0.8 1.3 0.6 1.0 1.4 1.6 2.7 1.4 0.9 1.4 YBL101C 1.0 1.1 1.9 0.9 1.0 0.9 0.8 0.8 3.0 1.4 YBR046C 1.4 1.4 1.7 1.8 1.3 2.6 3.9 1.6 4.6 6.2 YBR139W 1.2 1.4 3.1 1.4 0.8 2.4 1.9 0.7 2.3 1.6 YBR170C 0.8 1.2 0.6 1.4 1.5 1.4 1.9 1.3 6.1 4.2 YBR177C 0.8 1.1 4.0 1.2 1.2 2.3 0.9 0.9 2.1 1.7 YBR212W 0.7 1.2 2.6 1.2 1.0 1.4 0.9 0.6 2.7 2.3 YBR239C 1.0 1.3 0.9 1.5 0.8 1.5 1.0 1.3 0.4 1.2 YCL033C 1.1 2.0 1.7 1.7 1.2 4.6 2.4 1.1 2.3 1.4 YCR062W 0.8 1.9 2.7 2.8 1.4 1.9 0.9 0.7 0.7 1.3 YCR067C 0.9 0.7 1.2 1.3 0.7 0.8 0.8 0.7 1.8 1.6 YDL020C 2.3 1.2 3.4 1.1 1.2 2.5 1.0 2.2 5.6 2.9 YDR168W 1.2 1.4 1.0 0.8 1.5 1.3 2.4 2.1 3.7 2.3 YDR169C 1.0 1.4 1.1 1.3 1.3 1.2 1.1 1.0 1.6 1.4 YDR188W 0.8 1.2 1.0 0.8 0.8 0.8 0.9 1.0 2.9 1.6 YDR264C 0.5 2.6 0.9 1.4 0.9 1.8 3.2 0.8 1.1 3.4 YDR304C 1.0 1.8 2.7 1.3 1.5 2.1 2.0 1.3 3.9 1.9 YDR403W 1.0 1.2 1.6 1.0 1.2 1.1 1.2 1.2 4.1 3.6 YDR427W 0.8 1.1 0.8 0.8 1.5 1.9 1.4 1.2 2.3 2.0 YEL012W 1.3 1.8 1.0 1.8 1.7 1.6 4.7 1.4 4.6 4.2 YER009W 1.3 0.6 2.4 1.2 1.2 2.0 2.8 1.0 0.7 1.0 YER021W 0.8 1.0 0.9 0.9 1.4 1.1 1.5 1.2 3.0 2.2 YER094C 1.0 1.3 0.9 1.1 1.9 1.1 1.8 1.3 2.3 1.7 YER177W 1.4 1.5 2.1 1.5 0.9 1.6 1.2 1.1 1.8 1.7 YFL029C 1.0 1.2 1.2 1.8 1.7 1.0 1.6 1.5 4.3 2.9 YFL038C 1.0 1.2 0.7 1.3 1.5 1.3 1.7 1.4 2.1 1.9 YFR004W 1.0 1.5 0.8 1.4 1.0 1.5 1.3 1.4 3.6 2.6 YFR050C 0.9 1.2 1.1 1.3 1.7 1.5 1.4 1.4 3.1 2.1 YGL011C 1.2 1.5 1.1 1.1 1.8 1.6 1.5 1.3 2.0 2.2 YGL094C 0.8 1.3 0.3 0.9 1.3 1.0 0.8 1.0 1.4 1.1 YGL150C 0.7 0.8 1.2 1.0 0.8 1.1 0.8 0.8 1.4 0.9 YGL207W 0.5 0.6 0.9 0.6 1.3 0.9 0.6 1.0 1.4 1.1 YGR232W 1.2 1.2 1.2 1.7 1.5 1.9 2.0 1.1 3.4 2.2 YGR248W 1.3 1.7 3.2 4.0 0.5 2.3 1.1 1.2 2.8 3.2 YGR253C 1.3 1.4 0.7 1.3 2.0 1.4 1.6 2.0 4.0 3.1 YHR027C 0.5 0.8 1.2 0.6 1.1 0.4 0.9 0.6 3.6 2.2 YHR161C 0.6 1.1 1.3 2.1 1.5 1.2 1.8 0.7 2.5 2.0 YHR169W 0.6 0.5 0.4 0.4 1.1 1.2 0.9 0.9 0.0 0.2 YIL010W 1.0 1.2 1.4 0.8 1.2 4.4 1.5 0.9 1.4 2.2 YIL034C 1.0 0.8 1.5 3.0 0.7 1.7 1.2 0.9 2.1 1.3 YIL142W 0.7 1.1 0.9 1.1 0.8 1.1 0.8 1.1 4.4 3.0 YIR039C 1.4 1.8 4.3 4.2 1.5 3.2 4.1 1.1 4.4 4.1 YJL001W 0.9 1.7 1.2 2.0 1.7 1.6 1.3 3.1 2.8 YJL035C 0.9 1.3 0.8 0.6 1.4 0.7 1.3 1.5 1.7 1.4 YJL053W 1.1 0.9 1.7 1.3 1.1 2.0 1.7 1.3 2.2 2.2 YJL164C 1.1 1.1 1.0 1.9 1.1 2.7 3.1 0.9 2.1 0.8 YJL210W 1.2 1.4 1.6 2.0 0.6 0.6 1.0 1.0 2.0 0.9 YJR117W 1.0 2.1 2.3 0.7 1.2 1.3 1.0 0.8 4.7 2.3 YKL007W 1.2 1.6 1.2 0.9 1.0 0.9 1.5 1.2 2.3 2.4 YKL117W 1.0 1.3 0.8 1.0 1.8 1.0 1.3 1.5 2.9 2.1 YKL193C 1.3 0.8 1.1 1.4 1.1 0.9 2.1 1.4 1.0 1.6 YLR120C 1.2 1.9 2.4 1.6 1.1 1.9 1.5 0.9 1.8 1.6 YLR136C 1.3 9.0 0.6 3.3 1.6 1.7 3.9 1.1 0.9 6.0 YLR178C 1.7 6.9 8.8 4.6 1.0 4.2 3.3 0.9 4.3 4.1 YLR327C 5.5 3.3 14.4 8.2 1.3 5.1 5.7 2.2 3.0 8.3 YLR356W 1.0 2.9 4.9 1.2 1.1 3.4 1.1 0.7 2.3 1.6 YLR362W 1.1 1.2 1.0 3.0 1.5 0.8 1.9 1.4 3.5 3.3 YLR429W 0.7 1.0 0.6 0.9 1.4 0.8 1.3 1.0 0.9 1.3 YMR004W 0.9 0.9 1.3 1.3 1.0 0.5 1.2 1.0 94.2 3.4 YMR219W 0.7 1.1 1.0 0.7 1.6 0.8 1.1 2.3 0.9 YMR275C 0.7 0.7 1.2 0.6 0.7 1.4 0.8 0.8 2.4 2.1 YMR314W 1.2 0.9 1.3 1.3 1.1 1.2 5.9 2.7 YNL006W 1.1 2.1 1.3 1.5 0.9 1.0 1.6 1.1 4.0 4.0 YNL007C 0.7 2.4 5.1 0.8 1.2 0.6 1.2 0.8 3.0 1.7 YNL093W 2.1 6.4 0.4 4.5 1.2 1.6 1.4 0.8 1.7 2.0 YNL333W 1.0 1.4 1.7 2.3 1.5 1.5 2.9 2.1 2.3 2.1 YNR010W 1.3 1.2 0.5 2.8 1.8 1.3 1.5 1.1 1.7 0.9 YNR069C 1.5 1.3 0.7 0.4 1.4 1.7 1.4 1.4 5.5 5.8 YOL164W 0.9 4.4 1.0 1.5 1.6 1.2 2.2 1.0 4.9 3.6 YOR036W 1.8 0.9 1.4 1.6 1.1 1.7 1.8 1.4 1.2 1.9 YOR117W 0.8 1.3 1.7 0.8 1.2 1.1 3.3 1.0 3.5 1.8 YOR124C 0.6 1.1 1.3 0.8 1.1 0.9 1.1 1.3 2.0 1.9 YOR132W 0.9 1.6 0.8 2.8 1.1 1.6 1.4 1.2 2.8 1.6 YOR157C 1.0 1.3 1.2 1.3 0.7 1.2 1.2 1.2 5.7 2.6 YOR185C 1.1 1.3 1.9 1.1 1.2 3.0 1.3 1.4 1.9 2.9 YOR259C 0.8 1.1 0.8 0.9 2.0 0.8 1.3 1.1 2.7 1.5 YOR261C 1.0 1.4 0.6 0.9 1.5 1.4 1.9 2.6 5.5 2.5 YOR288C 0.9 1.3 1.1 1.1 1.1 1.0 2.0 1.9 0.9 1.0 YPL109C 1.1 2.5 0.5 1.2 1.2 1.2 1.8 1.1 1.2 1.5 YPL149W 1.5 1.5 0.6 2.8 0.8 0.9 1.2 1.1 5.6 3.7 YPL154C 0.7 3.3 4.2 1.2 1.2 3.5 1.5 0.8 2.8 1.7 YPR103W 0.7 1.1 1.3 0.7 1.7 1.2 1.6 1.0 5.5 2.0 YPR108W 0.8 1.0 1.3 0.6 1.3 1.5 1.6 1.6 3.7 2.8 YCL027W 0.7 2.0 1.0 1.0 1.2 1.3 1.0 0.6 0.7 16.3 YDR055W 1.7 2.1 2.2 2.8 1.7 3.9 1.5 1.6 0.8 2.4 YEL042W 0.6 0.9 1.7 0.9 0.7 0.5 0.5 0.7 0.2 0.3 YGR136W 0.9 1.2 1.3 0.7 1.2 1.1 1.5 1.3 2.1 2.2 YHR142W 1.5 0.8 2.1 0.8 1.3 1.2 0.9 1.3 0.4 0.9 YJL073W 0.8 0.8 2.5 0.7 1.2 2.0 1.0 1.7 0.7 YJR004C 0.2 0.8 3.4 0.6 1.1 1.2 0.4 0.4 0.3 0.7 YKL039W 0.8 1.1 2.4 0.8 0.7 4.9 2.0 0.8 1.3 3.3 YLR250W 1.5 1.0 1.0 1.4 1.4 1.1 1.9 1.3 2.7 2.4 YOR181W 1.0 0.9 1.1 1.4 0.7 0.9 0.7 0.7 0.6 0.5 YOR198C 1.0 0.7 1.4 1.0 0.8 0.9 1.6 1.3 2.4 1.4 YPL089C 1.2 1.0 0.5 1.8 1.4 0.8 0.9 0.8 0.4 2.5 YBR214W 0.9 2.1 5.7 2.0 1.1 0.8 1.1 0.7 2.2 3.5 YDR085C 1.9 1.8 1.6 3.4 0.9 2.1 4.1 2.0 0.4 2.3 YDR259C 1.4 1.0 0.4 1.4 1.0 0.5 2.8 1.4 1.0 1.8 YDR388W 0.7 0.7 1.2 1.0 0.7 1.0 1.1 0.8 1.4 0.9 YDR432W 0.5 0.8 1.0 1.4 1.6 0.6 0.5 0.5 0.7 0.8 YDR481C 0.7 2.3 1.3 0.7 1.0 0.9 0.7 1.0 1.9 1.6 YDR510W 1.0 1.3 1.5 1.3 0.7 1.0 1.6 1.5 2.7 2.5 YGR189C 1.1 0.9 1.5 3.5 0.7 0.5 0.6 1.0 0.3 0.9 YIL123W 1.0 0.5 1.2 1.5 0.6 0.5 0.5 0.6 0.1 0.2 YIL140W 0.7 1.0 1.5 1.4 0.8 0.5 0.5 0.7 0.7 0.6 YKL096W 1.4 0.6 8.1 1.6 0.6 0.6 0.2 0.5 0.0 0.5 YLR391W 0.7 2.9 0.8 1.2 1.5 0.7 0.7 0.4 0.7 YMR094W 1.0 0.5 1.3 1.7 0.9 0.5 0.8 1.0 −0.1 0.9 YMR104C 1.9 14.3 2.2 2.6 0.7 1.9 1.5 0.9 0.6 3.2 YMR276W 0.6 1.4 1.5 0.7 1.3 0.8 1.1 0.8 1.8 1.7 YOL013C 0.9 1.0 1.0 1.5 0.7 1.1 1.7 1.0 0.8 1.0 YOR355W 0.7 0.6 1.1 0.8 1.0 1.6 1.1 0.8 0.1 0.8 YCR071C 1.1 0.7 0.9 0.8 1.2 2.5 1.4 0.9 0.6 1.2 YDL008W 1.1 1.0 1.0 1.1 1.8 2.7 2.0 1.2 2.3 3.0 YDR115W 1.3 0.9 0.6 1.5 1.4 2.3 1.6 1.3 1.1 1.0 YER130C 0.9 1.6 0.5 0.8 1.7 2.7 1.5 1.2 0.5 1.3 YMR226C 1.1 1.8 1.4 1.6 0.9 2.6 1.8 1.6 2.6 2.2 YOR383C 0.9 4.3 2.6 0.9 0.9 6.8 8.0 1.0 1.2 4.5 YAR010C 0.8 1.2 1.2 0.8 1.0 2.3 1.9 1.3 1.2 1.1 YBL043W 1.2 1.2 1.1 1.3 1.1 26.9 1.5 2.1 0.5 14.7 YCR004C 1.7 1.0 12.0 1.2 1.8 1.4 1.2 4.7 2.1 YCR088W 0.9 1.1 1.2 0.9 1.1 2.0 1.2 0.5 0.8 0.9 YDL238C 0.7 1.0 1.1 1.7 0.9 2.1 1.4 5.8 1.7 2.7 YDR084C 0.9 0.9 1.5 1.1 1.2 2.1 0.9 0.7 0.6 0.6 YDR104C 0.8 1.1 1.2 1.2 1.3 1.7 1.0 1.3 2.8 2.7 YDR315C 1.0 1.4 1.0 1.3 0.9 9.4 1.4 1.4 1.1 1.6 YDR358W 0.7 1.1 0.7 1.1 1.4 2.5 2.8 1.2 2.9 3.2 YEL066W 2.0 2.9 1.5 2.2 0.8 2.2 1.8 1.4 1.3 2.4 YER039C 1.0 1.2 1.0 4.1 1.5 1.6 1.3 0.7 1.2 0.8 YER107C 0.9 0.5 1.0 0.6 1.3 2.5 1.0 0.8 0.4 0.5 YFL028C 1.2 1.1 0.7 1.5 1.7 1.7 2.0 1.5 2.7 1.8 YFL043C 1.0 1.2 0.6 1.2 1.2 1.8 1.8 1.0 2.2 3.8 YGL229C 0.6 0.7 0.9 0.8 1.0 2.2 2.2 0.7 1.8 1.7 YGR257C 0.7 0.8 0.9 1.1 1.3 2.1 2.4 1.0 1.5 1.9 YHR004C 0.9 1.1 0.8 1.1 1.5 2.0 1.5 0.9 1.1 0.6 YHR071W 1.5 1.1 0.6 1.6 1.5 2.0 1.0 1.7 1.0 7.2 YJL089W 1.1 1.5 1.0 0.8 1.1 1.6 1.1 1.1 1.6 3.9 YJL116C 0.9 1.8 1.3 1.9 1.3 3.4 0.8 1.8 2.4 2.6 YJR086W 1.2 1.1 0.8 1.4 1.3 1.9 1.7 1.1 1.4 1.1 YKL008C 1.2 0.6 2.0 0.8 0.9 3.8 1.4 1.2 0.3 0.4 YKL013C 1.4 0.9 1.4 1.1 1.9 1.9 1.8 0.9 1.5 1.4 YKL041W 1.2 0.8 1.1 1.0 1.3 2.2 1.0 1.6 1.6 1.5 YKL139W 0.9 0.7 1.4 0.8 2.8 3.5 2.6 1.2 1.6 1.5 YKR014C 1.1 1.3 0.7 1.1 1.5 2.1 1.7 1.6 2.4 2.0 YLR093C 1.3 0.8 0.7 1.2 1.4 2.9 1.9 1.2 1.5 1.3 YLR118C 1.0 1.1 1.6 1.0 1.0 2.5 1.5 1.0 1.1 1.3 YLR251W 1.8 0.8 4.2 4.6 1.6 2.1 2.6 1.2 2.1 1.3 YMR027W 0.8 2.6 0.7 0.8 1.1 2.1 2.0 0.9 1.1 1.4 YMR262W 1.0 1.3 1.9 1.1 1.2 2.0 1.9 1.0 3.0 1.2 YNL214W 1.2 0.9 1.1 1.1 1.4 2.3 1.3 1.1 1.5 1.5 YOR149C 0.7 0.9 1.0 0.8 1.1 2.3 1.0 0.7 0.4 1.0 YOR165W 0.9 1.5 0.7 0.8 0.8 2.2 0.9 1.1 0.8 1.3 YOR285W 1.4 6.0 3.5 1.9 1.7 2.1 4.0 1.2 4.0 2.9 YOR367W 1.0 0.9 1.7 0.9 1.1 3.3 1.9 1.1 1.1 1.1 YPL018W 1.0 1.4 1.0 0.5 1.8 2.1 0.9 1.1 1.4 1.2 YPL203W 1.3 1.0 2.2 1.0 2.1 1.8 2.1 1.1 1.8 2.1 YPL255W 0.8 0.3 1.1 0.6 0.9 2.0 0.6 0.9 0.1 0.1 YPR073C 1.2 1.9 0.5 1.4 1.8 2.0 2.5 1.5 1.3 2.6 YDR518W 0.8 1.7 1.1 1.2 1.6 1.2 2.7 1.1 0.2 1.2 YOR381W 0.8 2.0 0.8 1.8 1.0 1.0 3.6 0.8 1.2 3.5 YBR109C 1.6 1.3 2.4 1.1 1.0 1.4 2.4 1.7 3.8 3.3 YBR201W 1.2 4.3 1.2 2.4 1.2 1.0 3.4 2.2 0.8 1.0 YDR041W 1.2 1.1 0.6 1.8 2.0 1.6 2.4 1.2 1.3 1.3 YER136W 0.9 1.1 1.1 1.4 1.6 1.3 2.1 1.3 1.4 1.6 YER159C 1.1 0.9 0.2 1.6 2.1 1.3 2.0 1.4 0.2 0.9 YJL030W 1.6 1.4 0.5 1.0 1.3 1.1 1.9 1.6 2.3 1.9 YJR029W 0.8 1.3 0.6 0.8 1.0 2.4 0.9 1.1 1.5 YJR099W 1.4 0.9 1.1 1.3 1.5 2.1 2.0 1.4 1.4 2.4 YJR122W 2.0 1.4 2.5 1.1 1.3 1.4 1.8 1.4 5.3 6.1 YJR125C 1.0 1.0 1.2 1.0 1.2 1.3 1.9 0.9 1.8 1.3 YKL190W 1.1 1.3 0.4 0.9 1.5 2.0 1.1 1.8 1.9 YLL051C 0.8 1.1 1.0 1.5 1.4 1.2 2.0 0.9 0.9 1.8 YLR090W 0.7 1.1 0.8 1.3 1.2 1.3 2.2 0.9 1.8 1.4 YMR051C 0.9 2.8 0.8 1.3 1.7 1.2 2.6 0.9 1.0 1.4 YMR139W 1.0 3.4 2.5 1.5 1.2 1.5 2.2 0.9 2.8 2.4 YNL015W 2.3 6.7 1.8 2.4 1.8 1.7 3.5 2.2 2.1 4.3 YNL079C 1.1 1.0 0.4 1.0 1.7 1.1 1.9 1.6 1.5 1.2 YNL223W 1.1 1.2 0.6 1.7 1.0 1.8 2.2 1.4 3.3 1.9 YNR007C 1.2 1.8 0.7 1.0 1.5 1.3 1.9 1.2 2.5 2.0 YNR035C 0.8 1.2 1.7 1.0 0.8 1.1 2.6 1.1 2.9 1.5 YOL016C 1.3 2.0 0.4 2.0 1.6 0.9 3.0 1.3 1.9 1.6 YOL104C 1.0 1.7 0.2 1.8 1.9 1.4 2.6 1.4 0.2 1.7 YPR107C 1.4 1.0 1.2 1.9 1.5 1.3 2.0 1.3 2.4 2.4 YOL152W 0.2 0.6 1.0 0.8 0.7 1.8 2.4 4.1 0.9 1.2 YAL007C 1.3 0.9 0.9 1.5 0.6 0.7 1.5 1.7 1.1 0.9 YDL043C 1.0 0.8 0.8 1.2 1.1 0.5 0.9 1.3 0.8 0.8 YDL212W 1.0 1.2 1.6 1.2 1.1 0.4 0.7 0.9 0.4 0.6 YDR183W 1.2 0.7 0.9 1.4 1.5 1.4 1.8 1.8 2.5 2.9 YGL089C 0.4 0.7 2.0 1.0 1.5 0.5 0.4 1.0 0.0 1.9 YGL096W 1.9 2.9 1.2 2.5 0.9 0.5 1.8 1.7 2.1 3.6 YGR006W 1.2 1.1 0.9 2.9 0.5 0.5 1.0 1.2 0.7 0.9 YHL034C 0.7 1.0 0.7 0.8 1.9 1.1 1.4 1.4 1.9 1.9 YHR163W 0.9 1.2 1.3 1.2 0.8 1.9 0.9 1.3 1.4 1.1 YIR024C 1.5 0.9 0.9 2.0 1.1 0.8 1.5 1.4 5.6 2.9 YKL070W 1.0 0.8 1.7 0.9 1.3 1.1 1.1 1.5 15.0 11.0 YLL050C 1.4 1.0 1.2 1.7 1.9 1.4 1.3 1.0 1.0 YLR220W 0.9 0.6 3.0 1.0 0.9 0.3 0.4 1.0 0.4 0.4 YLR390W 0.9 0.9 1.2 1.7 1.2 0.7 1.5 0.8 1.7 1.7 YOL044W 1.0 1.4 1.0 1.3 1.0 1.2 1.2 1.1 1.6 1.4 YOL147C 1.6 1.1 2.4 1.5 0.7 0.9 0.6 1.5 0.5 0.7 YDR069C 1.4 0.8 3.0 1.5 1.6 0.7 1.0 1.8 1.8 4.5 YER131W 1.5 0.3 0.9 0.7 1.6 0.9 0.6 2.0 0.0 0.6 YGR044C 0.8 1.3 0.7 1.2 1.1 1.4 1.3 1.8 0.9 0.8 YMR240C 1.1 0.6 2.5 0.7 1.4 0.8 1.1 2.3 0.5 1.1 YBR105C 1.7 1.5 0.9 2.0 0.8 1.8 2.0 1.2 1.1 3.3 YBR182C 2.0 1.9 1.0 2.4 1.4 1.0 1.7 1.3 0.6 3.2 YBR186W 1.0 1.0 1.1 1.7 1.0 0.5 0.9 0.9 1.0 2.4 YEL052W 1.1 1.0 2.0 2.0 1.3 1.2 1.2 1.2 3.0 3.4 YER098W 0.9 0.9 0.5 1.1 1.4 1.6 1.3 1.7 2.8 3.3 YGL240W 0.9 1.2 0.8 1.8 1.2 1.1 1.2 0.8 2.0 3.4 YGR067C 2.2 1.4 1.2 4.6 1.6 1.3 1.5 1.5 0.7 6.7 YGR133W 1.0 1.1 0.7 0.6 1.3 1.2 1.2 1.2 1.3 3.6 YHR124W 1.1 1.1 1.5 2.0 0.9 0.8 1.2 1.1 3.0 6.8 YJL103C 1.3 1.8 3.8 1.3 1.1 1.0 0.7 0.8 2.3 2.4 YJR036C 1.2 1.2 1.0 4.3 1.5 0.9 1.0 1.0 1.4 3.0 YLR216C 1.2 2.3 3.3 1.1 1.2 1.2 5.2 1.3 14.1 4.1 YLR389C 0.8 6.4 2.3 0.6 0.7 0.2 1.0 1.0 2.4 2.8 YNL128W 1.3 4.6 1.1 0.8 1.2 1.1 1.0 1.3 2.9 2.4 YOL133W 1.0 1.6 1.4 1.2 0.9 1.6 1.8 1.0 4.7 3.8 YOR133W 1.1 1.3 1.6 1.3 1.3 0.9 1.1 0.8 3.1 4.9 YOR227W 1.1 2.4 3.2 0.9 0.5 1.0 1.0 0.7 2.9 3.0 YPR015C 1.3 1.3 1.5 1.7 1.1 0.7 1.3 1.2 5.6 5.3 YPR086W 1.0 1.4 0.7 0.7 1.2 1.1 1.6 1.3 3.0 2.9 YBL056W 0.7 0.7 1.1 1.2 1.8 1.6 1.4 1.3 3.6 2.2 YBR026C 1.1 1.7 2.8 0.9 1.2 0.1 1.1 3.4 1.6 YBR123C 0.8 0.7 1.6 1.8 1.1 1.3 0.9 0.9 3.2 2.5 YDR099W 0.9 1.0 2.0 1.3 1.1 2.2 1.3 1.1 2.4 1.3 YDR177W 1.2 1.7 1.0 1.0 1.0 1.4 1.3 1.6 3.5 1.9 YDR392W 0.9 2.9 1.1 1.3 1.2 0.6 1.1 1.1 4.3 1.5 YDR394W 0.9 1.2 1.3 0.8 1.2 1.1 1.2 1.3 3.8 2.0 YER184C 2.3 1.6 1.1 2.3 1.0 0.6 0.9 1.1 4.6 3.2 YFL059W 1.2 1.4 1.2 2.2 1.1 1.0 1.3 1.5 4.1 4.2 YGL185C 1.3 1.9 1.9 1.9 0.8 0.8 1.9 1.5 4.1 2.3 YHL019C 1.1 0.8 1.2 0.6 1.0 1.2 1.1 1.0 2.1 1.4 YHR012W 1.1 1.0 1.2 1.0 1.6 1.2 1.2 4.9 2.2 YHR028C 0.8 1.2 1.4 0.8 1.0 0.9 1.2 0.8 3.7 2.2 YHR109W 0.8 1.0 0.0 0.7 1.3 1.4 1.4 1.2 2.4 1.8 YHR156C 1.3 1.3 0.9 2.1 1.9 1.0 1.2 1.2 3.6 1.9 YIL159W 1.1 1.6 1.3 0.7 1.2 2.3 0.6 1.1 5.9 1.6 YJL154C 0.6 2.7 0.7 0.6 1.2 1.3 1.5 1.0 2.3 2.0 YJR110W 1.0 0.6 1.0 1.4 1.3 0.9 0.9 1.1 4.9 2.3 YKL025C 0.7 1.1 1.1 0.9 1.1 0.9 0.9 0.9 2.8 1.7 YKL171W 0.9 1.3 1.2 2.1 0.9 0.4 0.9 0.8 8.2 1.8 YKL196C 1.2 1.1 0.5 0.9 1.3 0.9 1.5 1.3 4.3 2.0 YKR068C 1.2 1.5 1.0 1.8 1.1 1.4 1.4 1.3 2.4 1.9 YLR144C 0.8 1.5 4.0 1.3 0.7 0.9 0.7 1.1 2.8 1.5 YML112W 1.0 1.0 1.1 2.0 1.0 1.4 0.9 1.3 3.2 2.4 YOL038W 0.9 1.0 0.4 1.6 1.8 1.2 1.4 1.4 3.5 2.7 YOR257W 1.1 2.5 0.8 1.1 1.1 0.8 1.3 1.5 3.4 1.4 YOR265W 1.4 1.0 0.8 1.0 1.2 1.4 1.3 1.4 3.5 2.2 YPL124W 1.3 1.3 0.7 0.7 1.6 0.8 0.9 1.8 2.2 1.0 YPR125W 0.6 1.3 0.9 1.2 0.7 1.3 1.2 4.1 1.8 YPR168W 0.9 1.0 0.2 0.5 1.3 0.4 1.1 1.1 4.7 2.7 YPR180W 0.9 1.2 1.6 1.0 1.0 0.8 2.4 1.3 2.3 1.1 YPR193C 1.0 2.2 0.6 1.1 1.4 1.3 1.4 1.1 3.5 4.1 YBR045C 0.9 1.0 2.2 0.7 1.0 0.8 0.8 1.0 3.6 1.1 YBR128C 1.0 1.1 2.1 1.0 1.1 1.5 2.1 1.2 2.8 1.2 YCL055W 0.7 2.2 0.7 1.3 1.2 1.4 1.0 1.3 2.1 1.5 YCR019W 1.0 1.6 1.0 0.8 1.4 1.5 1.1 1.5 2.8 1.6 YDL065C 1.2 0.9 1.0 0.7 1.4 1.1 1.3 1.4 2.4 1.5 YDL143W 0.8 0.8 1.2 1.1 1.0 1.0 0.9 1.2 2.1 1.8 YDL197C 1.0 1.1 0.9 2.1 1.5 1.2 1.0 1.0 2.6 1.5 YDL230W 1.0 0.8 1.2 1.3 1.4 0.9 1.1 0.9 2.6 1.2 YDR212W 0.8 1.2 1.3 0.8 1.4 1.4 1.0 1.3 3.5 1.7 YDR257C 0.8 5.3 0.6 0.8 1.6 1.1 1.0 1.0 3.0 1.6 YDR329C 0.9 0.8 1.0 1.7 1.9 1.2 1.6 1.2 2.5 1.0 YDR488C 1.0 0.3 0.9 0.9 0.9 0.9 0.7 0.9 2.1 0.4 YDR505C 0.8 1.0 1.0 1.4 1.2 1.1 1.2 0.8 2.5 1.0 YDR506C 0.9 0.7 1.3 0.7 0.9 0.9 0.6 1.0 1.9 1.4 YDR515W 0.9 1.1 0.8 0.8 1.5 0.8 0.6 1.4 5.8 2.7 YEL005C 1.1 1.3 0.8 1.1 1.6 1.9 2.0 1.2 2.3 1.6 YER048C 0.8 1.2 0.4 1.4 1.8 1.9 1.9 1.6 2.3 1.1 YER078C 0.9 0.8 1.8 0.8 0.9 1.4 1.3 1.1 2.3 1.5 YER089C 0.5 0.5 1.4 1.1 0.8 0.6 0.9 0.5 2.0 2.3 YER100W 1.1 1.1 0.7 0.7 0.9 0.5 0.6 1.2 2.3 1.6 YFR051C 0.5 1.1 2.2 0.5 0.5 0.2 1.0 0.8 2.5 1.4 YGL093W 0.8 0.9 1.2 0.6 0.9 1.0 0.8 0.8 4.5 1.6 YGL105W 0.9 0.8 1.1 0.8 1.3 1.5 0.7 1.2 1.8 1.4 YGL166W 1.0 1.4 0.6 1.5 1.3 1.0 1.5 1.2 1.8 2.4 YGL215W 0.7 1.2 1.2 0.9 1.0 0.9 1.0 0.7 2.2 1.8 YGL216W 0.7 1.3 0.8 1.0 1.2 1.5 1.0 1.0 2.6 0.5 YGL221C 1.1 1.2 1.0 1.1 0.9 2.2 1.3 1.6 3.4 1.9 YGR186W 0.9 0.7 0.4 1.1 1.5 0.7 1.3 1.3 2.6 1.9 YGR270W 0.9 1.0 0.8 0.8 0.7 0.9 0.9 0.9 2.3 1.3 YGR274C 0.7 0.5 0.3 0.9 1.8 0.7 1.3 1.2 2.2 1.8 YHR082C 0.7 1.1 1.6 0.9 1.6 0.8 1.1 0.8 2.6 1.7 YHR160C 1.0 0.5 1.6 1.6 1.0 1.0 1.1 1.2 2.3 1.6 YHR171W 1.2 0.8 1.1 1.2 1.3 2.0 1.9 0.9 2.1 1.6 YHR205W 0.7 1.3 0.6 0.8 1.3 1.0 0.7 0.5 2.0 0.6 YIL062C 1.1 1.0 1.3 1.2 1.2 0.9 0.4 1.1 2.8 2.3 YIL075C 0.5 0.7 1.5 0.6 1.1 0.8 0.8 0.7 1.9 2.3 YIR009W 0.8 0.8 0.9 2.8 1.5 1.4 1.3 1.3 2.6 1.5 YIR018W 1.2 1.0 0.9 1.1 1.4 2.0 1.5 1.5 4.0 2.1 YJR091C 0.8 1.2 2.6 1.4 1.4 0.8 1.1 0.8 2.4 2.3 YKL079W 0.9 0.8 1.5 1.0 1.4 0.8 1.7 1.2 2.3 2.0 YKR102W 0.8 1.6 1.4 0.8 0.9 0.7 2.4 1.4 YLL054C 1.2 0.6 0.5 1.2 1.4 1.9 1.1 1.1 2.4 1.4 YLR200W 1.4 0.9 0.5 1.2 1.7 1.2 1.9 1.4 2.2 2.6 YLR248W 0.9 0.7 1.1 1.4 1.9 1.2 1.2 1.1 2.3 1.1 YLR266C 0.9 1.3 0.7 1.5 0.7 1.0 1.6 1.1 2.2 2.6 YML088W 0.9 1.6 0.3 0.5 1.5 0.7 1.1 1.1 4.0 2.2 YMR091C 1.0 0.7 0.8 1.0 0.7 0.8 0.8 1.3 2.1 1.3 YMR110C 1.0 1.4 1.8 1.9 1.3 2.1 1.9 0.9 2.3 1.6 YMR255W 1.2 1.4 0.7 1.8 1.3 0.9 1.5 1.4 2.8 2.4 YNL039W 0.7 0.8 0.3 0.4 2.1 0.8 1.1 1.2 2.1 1.8 YNL077W 1.5 1.1 2.3 1.2 1.5 0.9 1.2 1.0 4.4 5.1 YNL083W 0.8 1.4 1.3 1.2 0.8 0.7 0.9 1.1 3.1 1.6 YNL147W 1.3 2.4 0.6 0.7 2.0 1.5 1.4 1.8 2.1 2.9 YNR006W 1.1 1.8 0.5 0.9 1.5 0.9 1.5 0.9 2.2 2.3 YNR034W 0.9 1.4 5.3 1.6 1.0 0.9 1.3 1.0 3.0 2.1 YNR047W 0.7 1.0 1.7 0.5 1.1 1.0 1.0 0.8 2.0 1.2 YOR023C 0.7 1.2 1.3 0.8 1.2 1.8 1.1 0.6 3.5 1.3 YOR058C 2.0 1.4 2.0 0.6 0.9 0.9 0.8 1.7 6.4 4.5 YOR069W 0.8 1.6 0.7 1.3 1.0 0.5 1.2 1.1 1.9 1.4 YOR229W 0.9 0.9 1.0 0.8 1.5 1.3 1.1 0.8 2.5 0.8 YOR256C 1.0 0.8 0.9 1.5 1.7 0.9 1.4 1.1 2.7 1.8 YPL020C 1.1 0.7 0.7 1.3 0.8 0.8 1.1 1.1 2.3 1.6 YPL105C 0.6 0.8 0.6 0.7 1.1 1.2 0.7 1.0 3.4 1.4 YPR066W 1.2 2.2 1.1 2.2 1.3 0.7 1.3 0.8 2.3 1.9 YPR081C 0.9 1.0 1.0 1.1 0.8 1.1 1.1 1.0 4.2 2.6 YPR140W 0.9 1.2 0.8 1.8 0.9 3.0 1.9 1.1 2.1 1.3 YPR155C 0.9 2.5 1.5 1.4 0.9 0.9 1.4 1.0 2.0 1.3 YPR185W 0.7 0.9 0.3 0.4 1.1 0.9 1.2 1.0 2.5 1.7 YBR076W 2.3 1.1 1.4 5.0 0.9 0.8 1.0 0.7 0.4 1.8 YDR373W 1.7 0.8 0.5 1.3 1.8 0.9 1.4 1.9 2.5 2.8 YFR014C 2.1 2.4 0.8 2.6 0.7 0.8 1.4 1.3 1.0 1.6 YHR136C 2.4 13.6 1.4 2.1 2.4 1.4 0.5 1.3 0.1 2.0 YIL129C 0.8 5.8 1.0 1.2 0.3 2.1 1.8 YMR077C 1.1 3.9 1.1 1.8 1.0 0.5 1.4 1.7 1.9 2.5 YBR264C 1.2 3.7 1.5 1.5 0.7 0.9 1.3 1.2 0.9 1.1 YPL177C 1.2 3.7 0.9 1.3 0.7 0.8 0.8 1.3 0.5 1.0 YGL056C 0.7 3.5 1.3 1.0 0.6 0.4 1.0 0.9 0.4 0.6 YBL101W-A 1.0 5.7 0.7 0.6 1.0 1.4 1.3 1.5 1.2 2.1 YER072W 1.6 2.3 1.6 1.3 1.2 1.5 0.7 1.2 0.5 1.1 YMR112C 1.2 4.2 0.9 1.2 1.0 0.7 1.5 1.6 1.4 1.3 YJR058C 1.3 2.0 1.3 1.5 1.1 1.6 1.3 1.2 1.9 2.6 YML055W 1.7 2.3 0.6 2.0 0.9 1.2 1.7 1.7 1.0 1.4 YDR080W 0.9 1.8 0.5 0.6 1.2 1.5 1.6 1.2 1.7 2.6 YNR030W 0.6 2.1 2.2 0.7 0.8 1.2 1.0 0.6 1.0 1.4 YNL196C 1.1 1.8 1.4 1.3 0.9 1.2 1.0 0.7 0.5 2.2 YOR148C 1.4 1.4 0.5 1.8 0.9 0.9 1.2 1.5 0.8 0.8 YER029C 1.0 1.6 0.4 1.9 1.7 1.2 1.1 1.5 1.4 1.1 YLR360W 0.9 2.0 0.5 0.7 1.9 1.4 1.7 1.3 0.9 1.3 YGR239C 1.3 1.3 0.7 1.3 1.2 2.3 1.2 1.5 0.5 3.8 YDL229W 0.9 1.9 0.4 0.6 1.2 1.0 1.3 1.2 1.4 0.9 YJR027W 0.8 1.9 0.8 0.7 1.5 2.0 1.0 1.2 1.3 YKL198C 1.2 1.4 0.8 0.2 0.9 1.0 1.2 0.6 0.0 0.8 YBR031W 1.1 0.8 4.1 1.4 1.4 0.7 0.5 1.0 0.1 1.0 YBR118W 1.3 0.8 2.9 1.2 1.0 1.3 1.0 1.3 0.5 0.9 YCR106W 0.9 1.1 2.8 1.1 0.8 1.4 0.9 0.8 2.0 1.2 YDR012W 0.9 0.8 3.9 1.2 1.1 0.9 0.5 1.1 0.3 0.7 YDR134C 1.0 0.7 3.9 1.9 0.8 1.1 0.4 0.6 0.1 0.5 YDR276C 1.5 1.6 6.1 1.4 0.7 1.1 1.0 1.1 1.1 2.7 YGR279C 0.9 0.7 3.6 1.0 1.2 1.6 0.8 0.6 0.3 0.7 YJL059W 1.0 1.7 3.1 0.8 0.9 1.6 1.1 0.8 1.7 1.6 YKL056C 1.3 0.7 2.6 1.4 1.7 0.9 0.5 1.0 0.1 0.7 YKL097W-A 1.5 1.3 4.2 1.3 1.2 0.9 0.2 0.7 0.0 0.4 YNL209W 0.9 0.9 2.7 0.9 1.3 0.9 0.5 1.1 0.2 0.8 YNL307C 0.8 0.6 3.1 1.3 1.0 1.9 0.9 0.9 1.0 0.9 YPR028W 1.0 1.1 4.0 1.7 1.0 1.4 0.8 0.7 0.5 0.8 YPR149W 1.0 1.1 5.9 1.7 1.7 1.6 2.1 0.6 1.2 1.8 YAL016W 0.8 1.0 2.8 0.9 0.9 0.9 1.1 1.0 1.2 1.9 YBR283C 0.6 0.7 1.9 1.2 1.4 2.2 0.8 0.8 1.5 1.2 YBR286W 0.7 1.4 3.8 1.2 1.3 1.5 1.3 0.9 1.2 1.6 YCL008C 0.8 1.1 1.8 1.2 1.2 0.9 0.9 0.7 0.9 1.4 YCR069W 1.0 1.2 2.0 0.9 1.1 1.4 1.1 0.7 0.8 0.7 YDL061C 1.4 0.5 2.9 0.9 1.3 1.1 0.5 1.0 0.0 0.5 YDR151C 1.3 1.0 2.3 1.8 0.8 0.7 0.8 1.5 2.6 2.8 YDR382W 1.3 0.5 2.4 1.2 1.1 0.6 0.4 1.2 0.0 0.4 YDR385W 0.6 0.4 3.5 0.9 1.1 0.5 0.4 0.7 0.2 0.5 YDR407C 0.7 1.0 2.0 0.7 0.8 1.2 1.4 0.9 1.5 1.7 YGL206C 0.4 3.5 2.0 0.5 0.6 0.8 0.8 0.5 0.7 0.7 YGR172C 0.6 1.3 2.5 1.3 0.6 0.9 1.0 0.8 0.4 1.1 YIL015W 1.1 1.7 2.0 2.5 0.9 0.4 0.9 0.9 0.3 1.1 YIL018W 1.0 0.4 2.3 1.4 0.9 0.4 0.8 0.0 0.3 YJL138C 1.0 0.7 2.3 1.4 0.9 0.8 0.8 1.2 0.2 0.7 YJL191W 1.0 0.4 2.2 0.7 1.3 1.0 0.8 0.0 0.4 YJR047C 1.1 0.8 2.6 1.1 1.1 1.1 0.4 0.9 0.7 0.5 YJR119C 0.9 1.0 2.0 1.0 0.9 1.4 1.1 1.6 0.5 1.3 YJR123W 1.2 0.6 2.2 1.0 1.3 1.0 0.4 1.2 0.0 0.5 YJR145C 0.8 0.7 2.3 1.3 0.4 0.4 1.0 0.0 0.4 YLR110C 1.4 0.8 2.7 1.2 1.7 0.9 0.4 0.8 0.3 0.8 YLR264W 1.1 0.4 2.2 1.0 1.1 0.7 0.4 1.0 0.0 0.3 YLR340W 0.8 0.4 2.6 1.0 0.6 0.7 0.3 0.9 0.0 0.5 YLR388W 1.6 0.4 1.9 1.0 2.5 0.7 0.5 1.2 0.2 0.7 YMR092C 0.6 1.2 1.9 1.3 0.8 0.9 1.2 0.9 1.5 1.7 YMR101C 1.1 1.8 1.9 2.9 0.9 0.4 0.9 0.8 −4.0 1.6 YNL069C 1.2 0.3 2.8 2.3 0.7 0.4 0.3 1.0 0.0 0.4 YNL135C 1.1 0.9 2.0 1.4 1.7 0.9 0.8 0.5 0.7 0.5 YOL039W 1.2 0.3 3.9 0.7 1.3 0.4 0.3 1.0 0.0 0.9 YOL120C 1.0 0.3 2.3 0.8 1.5 0.3 0.4 0.8 0.0 0.3 YOR230W 1.2 2.3 3.0 1.0 0.9 1.1 0.6 0.6 0.6 0.7 YOR298W 0.9 0.9 3.2 0.5 1.5 0.9 0.6 0.7 0.6 1.0 YPL048W 0.7 0.7 2.6 1.2 0.7 0.6 0.6 0.8 1.6 0.6 YPL179W 1.0 1.5 2.4 1.0 1.1 1.6 1.2 0.8 1.2 1.1 YPL218W 1.5 0.9 2.5 1.7 1.1 1.5 1.3 1.4 1.1 1.2 YPL220W 1.3 0.9 2.3 1.4 1.1 1.3 0.6 1.2 0.0 0.5 YPR080W 1.3 1.3 2.8 1.2 1.4 1.4 0.9 1.3 0.7 1.1 YPR181C 0.5 0.8 2.3 0.6 1.0 2.0 1.3 0.5 1.0 0.7 YBR290W 1.3 1.4 0.8 3.0 1.0 1.1 1.4 1.5 2.0 1.8 YCR091W 1.3 1.1 0.6 2.2 1.3 1.3 1.3 1.1 0.8 1.2 YFL026W 1.0 0.8 1.2 5.0 1.4 1.0 1.2 1.3 0.6 1.5 YOR003W 0.9 1.1 1.3 3.3 1.6 1.1 1.1 0.9 1.6 1.3 YCR038C 0.9 1.1 0.9 2.5 0.9 0.9 0.9 0.9 0.7 0.7 YDL119C 1.0 0.8 0.6 2.2 0.9 0.6 1.3 1.1 1.3 1.1 YDL220C 0.9 1.3 1.1 1.6 1.2 1.8 1.1 0.8 0.2 1.3 YDR125C 1.1 0.9 1.0 1.7 1.1 0.8 1.0 1.2 0.7 1.9 YDR225W 1.0 0.6 0.6 1.6 1.9 0.5 0.4 0.8 0.3 0.7 YER066W 0.9 0.7 0.9 2.1 1.5 1.3 1.3 0.7 1.7 1.4 YER076C 0.8 0.9 1.2 1.9 1.1 0.6 0.8 0.7 0.2 1.2 YFR006W 0.9 1.8 1.1 3.4 0.7 0.8 1.4 1.0 −1.6 0.7 YGL208W 0.9 1.8 1.1 2.2 0.7 0.6 1.1 0.7 1.4 1.3 YGR023W 1.0 0.9 1.1 4.2 1.0 1.2 1.0 1.2 1.2 3.2 YGR108W 0.9 3.9 0.3 3.6 0.8 0.1 0.3 0.5 0.0 0.1 YHR195W 1.1 1.5 0.6 2.4 1.5 1.0 1.3 1.6 1.8 0.8 YIL050W 1.0 1.3 1.3 2.4 0.9 0.7 1.1 1.2 1.3 1.9 YJR050W 1.0 0.6 0.7 2.1 1.2 1.4 1.1 1.8 2.0 1.3 YKL093W 1.0 1.6 1.4 3.6 0.8 0.8 0.7 0.9 1.5 1.6 YMR053C 1.1 1.0 0.8 2.1 0.9 1.3 0.9 1.0 2.2 1.4 YNL139C 0.8 1.1 0.8 2.0 1.9 1.0 1.0 0.9 0.6 0.7 YOR122C 1.0 0.7 1.8 1.9 1.7 1.3 1.2 1.0 1.1 0.9 YOR312C 1.2 0.4 1.0 1.9 0.7 0.6 0.6 1.2 0.0 0.3 YOR327C 2.3 1.8 0.5 1.9 1.0 1.4 1.4 1.9 1.4 2.2 YPL001W 0.9 0.9 1.0 2.5 1.7 0.7 1.0 1.2 0.7 1.0 YPL230W 1.2 1.7 1.8 4.0 0.8 1.0 1.1 1.0 0.9 2.7 YER025W 0.6 0.7 0.6 0.6 1.5 1.0 1.5 1.1 0.4 0.6 YHR185C 0.9 1.1 1.4 0.7 1.4 1.0 1.3 0.8 −0.6 0.9 YIL076W 1.3 0.6 1.1 1.0 1.8 0.6 0.5 1.3 1.0 1.4 YMR238W 1.9 1.3 1.1 1.3 1.5 1.3 1.2 0.9 1.3 1.4 YBR009C 1.6 0.8 0.4 1.7 1.4 1.0 0.5 1.2 0.6 0.6 YBR010W 1.0 0.8 0.5 2.0 0.8 1.1 0.8 1.3 0.5 0.7 YCL067C 1.2 1.1 0.3 1.7 1.1 1.7 1.3 1.7 1.4 1.9 YCR096C 1.1 0.9 0.4 1.6 2.1 1.2 1.7 1.5 1.2 1.6 YDL137W 1.4 1.1 1.2 1.2 1.8 1.0 2.0 1.1 1.1 1.3 YDL192W 1.4 1.0 0.6 1.2 1.4 1.0 1.7 1.5 0.8 0.6 YDR224C 1.1 0.7 0.8 0.9 1.2 1.0 0.8 1.4 1.1 1.3 YDR378C 1.3 1.3 1.4 1.3 1.0 1.0 1.4 1.5 0.5 1.3 YMR197C 1.3 1.6 1.4 1.9 1.1 1.6 1.5 1.4 1.9 2.5 YOL109W 2.0 2.0 1.5 1.8 1.0 1.3 1.2 1.5 0.1 1.1 YPL010W 1.0 1.1 0.9 1.0 1.4 1.0 1.9 1.5 1.7 1.5 YHR132C 0.8 0.7 1.7 1.4 1.0 0.7 0.8 0.8 0.9 1.1 YJL141C 1.0 0.8 1.0 1.6 1.5 1.1 1.1 0.9 1.2 1.3 YKR098C 1.0 1.1 1.2 1.7 1.1 1.8 1.7 1.3 1.4 2.7 YLR206W 0.7 1.6 1.4 1.1 1.1 0.5 0.7 0.8 1.5 1.0 YAL055W 1.2 1.0 0.9 1.0 1.4 1.3 1.5 1.9 1.0 1.4 YAR062W 1.2 1.8 1.4 0.7 1.0 0.6 1.3 0.9 0.4 0.9 YBL102W 0.8 1.0 1.4 1.2 0.9 2.5 1.6 0.8 2.3 1.1 YBR161W 1.2 0.8 2.3 0.7 1.1 3.0 0.9 0.4 0.4 YCR039C 1.9 2.1 0.3 0.9 1.9 1.5 1.4 1.6 1.8 2.2 YDL018C 1.3 0.9 0.9 1.1 1.8 1.4 1.2 1.3 1.0 1.0 YDR022C 1.1 1.2 0.8 0.9 1.5 2.2 1.8 1.4 0.9 1.4 YDR181C 1.1 1.2 0.8 1.4 0.9 0.7 1.0 1.2 2.0 0.9 YGR036C 0.9 0.8 0.9 1.1 1.3 1.3 1.0 0.8 0.9 0.9 YGR120C 1.2 1.8 0.5 1.0 1.8 1.5 1.6 1.3 0.3 1.2 YGR131W 0.8 2.1 1.9 1.1 0.9 1.9 1.1 1.1 1.9 5.8 YGR167W 1.1 1.1 0.6 1.5 0.9 1.7 1.4 1.4 1.4 1.9 YHL024W 1.2 0.8 1.6 1.1 1.5 1.2 1.3 0.8 2.1 3.6 YJL113W 1.2 1.9 1.2 1.2 0.7 1.2 1.3 1.3 2.1 YJL146W 1.3 1.9 1.2 2.0 0.8 0.7 1.3 1.0 1.0 1.7 YJR019C 0.8 1.8 1.9 1.6 1.1 0.8 0.9 0.7 1.1 0.6 YJR049C 1.0 1.2 1.0 1.0 0.7 0.6 1.0 1.2 1.4 1.4 YLR078C 0.9 1.1 0.7 1.4 0.8 1.2 1.1 0.8 1.1 YNR037C 0.9 0.9 0.9 1.7 1.2 0.7 1.7 1.1 1.3 1.7 YOR028C 1.4 0.7 1.1 2.3 1.6 1.0 1.2 1.5 1.2 2.0 yeast The level of expressed mRNA in the absence of chemical substance genes (11) (12) (13) (14) (15) (16) (17) (18) Intensity YKR076W 18.6 1.5 5.1 14.7 3.2 9.6 1.8 2.7 0.27 YNL335W 1.1 0.8 0.9 4.6 1.7 1.0 1.2 1.1 0.22 YBR173C 2.5 1.7 3.8 3.0 15.4 2.1 0.9 1.6 1.15 YFL022C 1.2 0.6 0.6 3.1 1.1 1.3 0.9 0.8 1.07 YGL158W 0.2 1.3 1.0 2.3 2.3 8.2 0.8 1.1 0.18 YHR139C 3.5 1.6 7.0 2.5 1.9 17.1 1.4 1.3 0.34 YGR213C 1.6 10.6 30.4 1.0 6.5 5.2 12.8 8.5 0.22 YKL165C 0.3 2.4 3.2 0.8 2.1 1.2 0.9 1.0 1.08 YBL005W-A 0.8 1.6 2.9 1.4 0.9 1.1 1.3 1.0 0.48 YBL041W 1.6 1.6 2.6 2.0 1.3 2.3 1.3 2.0 3.03 YBL078C 4.6 3.1 5.0 3.6 2.5 4.4 1.8 2.8 0.65 YCL020W 1.3 1.5 3.0 1.7 2.5 1.3 0.9 1.3 1.46 YDL007W 1.3 1.1 2.4 1.4 1.4 0.8 0.8 1.5 2.43 YDL097C 1.5 1.3 4.0 1.4 1.1 1.1 1.0 1.3 2.06 YDL126C 1.4 1.3 4.3 0.6 1.7 0.7 0.9 0.9 3.24 YER012W 1.9 1.5 2.9 4.6 1.7 2.2 1.5 1.3 1.84 YFR010W 1.5 1.2 3.7 1.1 1.5 1.3 0.9 1.4 1.89 YFR024C 1.9 1.5 2.8 1.2 0.9 1.9 1.0 1.4 1.06 YGL048C 1.5 1.3 2.5 1.2 1.0 1.6 1.4 2.0 3.07 YGL141W 0.6 1.4 3.6 1.2 1.5 1.2 1.4 1.2 0.44 YGL180W 1.3 1.4 2.6 1.0 1.3 1.7 1.0 1.1 0.28 YGR048W 1.1 1.1 2.5 1.3 0.8 1.1 0.9 1.2 0.93 YGR135W 1.6 1.2 2.8 2.6 1.5 1.5 1.0 1.9 3.10 YGR201C 1.6 1.9 8.6 1.6 0.5 14.4 1.4 2.1 0.60 YHL030W 1.1 1.1 3.8 1.0 2.0 0.5 0.8 0.9 0.66 YHR166C 0.6 1.7 6.9 1.2 0.9 1.1 1.4 1.5 1.35 YJR069C 0.9 1.1 3.9 0.6 0.4 0.8 1.0 0.9 1.73 YKL073W 0.5 1.5 3.3 0.7 1.6 1.0 1.2 1.5 1.29 YKL103C 2.8 1.3 3.8 2.0 2.1 1.2 1.9 2.2 0.56 YLR080W 1.9 0.8 3.6 1.2 0.7 3.0 1.6 2.2 0.41 YLR107W 0.8 1.0 2.9 1.6 1.1 1.6 1.8 2.4 0.94 YLR121C 2.2 1.1 4.0 1.2 10.7 1.5 2.7 1.4 0.30 YLR336C 0.5 1.9 4.6 0.6 0.8 1.3 1.5 1.0 0.71 YLR370C 1.0 1.2 3.1 1.9 1.5 1.6 1.6 2.0 1.41 YLR423C 1.0 1.7 3.9 1.2 1.3 1.9 1.2 1.6 0.34 YML092C 2.5 1.2 2.3 1.6 1.4 2.2 1.3 1.5 1.72 YML130C 1.9 2.3 5.8 1.3 2.4 0.8 1.2 1.2 1.59 YMR214W 0.7 1.0 2.4 1.1 4.8 0.7 1.1 1.0 0.88 YMR297W 2.5 1.2 4.2 0.5 2.4 1.9 1.1 1.4 4.10 YNL036W 1.7 1.4 3.3 5.1 1.6 1.3 1.4 1.9 2.04 YOL005C 1.6 1.2 2.9 1.2 0.9 1.0 1.2 1.2 1.71 YOR134W 1.9 2.8 4.4 1.3 1.6 7.7 2.2 4.6 0.28 YOR362C 1.3 1.3 2.5 1.4 1.0 1.5 1.1 1.8 2.55 YAR009C 0.9 1.3 2.0 1.0 2.1 0.6 0.8 1.2 7.11 YBL101C 0.8 1.1 3.5 0.9 2.7 1.4 1.0 1.1 0.39 YBR046C 2.9 1.2 2.0 1.3 2.1 3.0 1.2 2.0 0.63 YBR139W 2.3 1.2 2.7 1.1 5.6 2.3 1.2 2.0 1.21 YBR170C 1.5 1.2 2.7 1.3 1.9 1.3 1.1 1.4 0.72 YBR177C 0.6 1.2 3.1 1.3 1.4 0.4 0.8 0.9 0.76 YBR212W 1.1 0.9 2.2 0.7 1.0 1.5 1.1 1.0 0.95 YBR239C 0.7 1.1 1.9 1.1 1.0 2.7 1.0 0.9 0.31 YCL033C 1.9 1.6 2.0 1.8 0.8 3.6 2.0 2.0 1.14 YCR062W 1.2 1.3 2.2 1.0 2.3 1.1 1.1 1.0 0.41 YCR067C 1.2 0.9 2.0 0.9 2.1 1.4 1.1 0.9 0.62 YDL020C 1.9 1.1 3.4 1.2 1.5 1.8 1.5 1.7 1.36 YDR168W 1.5 1.2 2.4 1.4 1.9 1.4 1.2 1.4 1.28 YDR169C 0.9 0.9 1.9 0.9 1.4 0.9 1.4 1.1 0.40 YDR188W 0.9 0.9 1.7 0.7 1.3 0.9 0.7 0.8 1.78 YDR264C 0.9 1.1 2.1 0.7 2.3 1.5 1.2 1.4 1.63 YDR304C 1.2 1.3 2.3 1.7 1.0 4.0 1.6 1.8 2.23 YDR403W 1.0 1.0 2.0 1.1 0.9 0.9 0.9 1.0 0.35 YDR427W 1.2 1.1 2.1 1.0 1.3 1.1 1.0 1.5 2.37 YEL012W 2.2 1.2 2.2 1.9 1.1 2.5 1.5 2.2 0.74 YER009W 1.4 1.1 2.0 1.6 0.9 1.5 2.0 2.1 3.35 YER021W 1.3 1.0 1.8 1.3 0.8 1.4 0.8 1.5 2.02 YER094C 1.3 1.1 2.1 1.5 0.8 1.5 1.3 1.8 3.01 YER177W 1.9 1.1 2.2 0.9 1.4 1.0 0.9 2.0 5.81 YFL029C 2.1 1.1 1.8 1.9 1.3 1.2 1.2 1.4 0.49 YFL038C 1.7 1.1 2.1 1.5 1.5 2.1 1.2 1.6 2.31 YFR004W 1.3 1.2 2.0 2.1 1.1 1.3 1.0 1.4 2.44 YFR050C 1.4 1.5 2.1 1.6 1.5 1.5 1.1 1.7 1.70 YGL011C 1.5 1.0 2.1 3.0 1.3 1.7 1.3 1.5 1.78 YGL094C 0.6 0.8 2.3 0.9 1.9 1.0 1.0 0.9 0.51 YGL150C 0.4 0.8 2.4 1.0 1.3 0.9 0.9 0.8 0.62 YGL207W 0.7 0.7 2.5 0.8 1.2 0.7 0.9 0.8 0.88 YGR232W 1.3 1.1 2.4 2.1 0.9 1.8 1.3 1.2 0.96 YGR248W 2.3 1.1 2.0 1.5 1.5 7.9 1.0 1.5 0.52 YGR253C 2.4 1.1 3.4 1.8 1.1 1.8 1.5 2.1 2.01 YHR027C 1.1 1.0 2.1 0.7 1.5 0.9 0.8 1.0 2.06 YHR161C 1.2 1.0 1.8 1.0 1.4 1.7 1.4 1.5 0.86 YHR169W 0.4 1.1 3.3 1.1 0.6 1.0 1.6 1.3 0.81 YIL010W 1.4 1.4 2.3 1.7 1.1 1.7 1.5 1.5 0.70 YIL034C 1.6 1.0 2.6 1.1 1.0 1.7 1.2 1.5 0.99 YIL142W 1.7 1.1 1.8 1.0 1.3 0.7 0.9 0.8 1.84 YIR039C 3.8 1.4 2.9 1.9 2.0 4.2 1.2 1.1 0.45 YJL001W 1.5 1.6 2.9 2.5 1.2 1.8 1.0 1.6 3.00 YJL035C 0.8 1.1 2.4 1.6 0.7 0.6 1.0 1.0 0.82 YJL053W 1.6 1.1 1.9 1.3 1.1 1.7 1.3 1.6 0.80 YJL164C 1.5 1.0 2.1 0.9 0.8 2.1 1.3 1.7 1.04 YJL210W 2.4 1.0 2.2 0.9 0.8 2.3 0.9 1.0 0.70 YJR117W 1.0 1.2 2.8 0.8 2.2 0.7 0.8 0.9 1.34 YKL007W 1.8 1.3 2.5 0.7 1.0 1.0 1.4 1.3 1.13 YKL117W 1.6 1.0 2.4 1.6 1.6 1.8 1.2 1.8 3.73 YKL193C 1.7 0.9 2.1 1.2 1.2 2.4 1.2 2.3 0.71 YLR120C 1.2 1.6 4.8 0.8 2.7 1.7 3.5 2.9 1.53 YLR136C 1.2 1.3 2.9 0.7 2.1 1.2 1.8 1.4 0.41 YLR178C 3.7 2.2 7.5 2.8 2.3 10.6 2.0 3.6 1.03 YLR327C 5.0 1.4 2.8 1.5 0.8 2.8 3.3 5.3 2.23 YLR356W 3.1 1.5 2.5 2.2 2.8 0.9 1.1 1.0 0.41 YLR362W 1.5 0.8 2.4 1.2 1.3 1.9 1.2 1.3 0.35 YLR429W 0.9 1.1 2.3 0.7 1.5 1.0 1.0 0.9 0.86 YMR004W 2.5 1.0 2.2 2.2 1.3 1.3 0.9 1.3 0.52 YMR219W 1.5 1.5 2.1 0.5 1.7 0.8 1.1 0.9 0.23 YMR275C 1.1 0.7 2.1 0.8 1.7 1.0 0.9 0.7 0.79 YMR314W 1.8 1.0 2.6 1.0 1.2 1.6 1.3 1.6 1.67 YNL006W 1.1 0.7 2.3 0.8 0.7 0.9 1.0 1.3 1.20 YNL007C 1.3 0.7 2.1 0.4 0.8 0.5 1.1 1.0 3.62 YNL093W 1.6 1.1 2.2 1.1 0.6 4.9 3.0 3.1 0.32 YNL333W 2.0 1.0 2.2 1.9 1.0 1.4 1.4 1.1 0.49 YNR010W 1.4 0.8 2.8 1.3 0.8 1.2 1.7 2.3 0.37 YNR069C 2.5 1.2 3.4 2.1 1.0 0.8 1.1 0.9 0.18 YOL164W 1.0 1.1 3.4 1.3 1.0 1.1 1.1 1.3 0.45 YOR036W 1.3 1.2 2.1 1.2 1.2 1.3 1.6 1.7 0.98 YOR117W 1.2 2.5 2.3 1.0 1.4 1.2 1.4 0.9 1.42 YOR124C 1.2 0.9 2.1 0.8 1.3 0.9 1.0 1.0 0.65 YOR132W 1.3 0.7 2.5 0.7 1.5 1.6 1.2 1.6 0.46 YOR157C 1.6 1.3 2.4 2.2 1.9 0.9 1.2 1.2 1.23 YOR185C 1.2 1.5 2.2 2.1 1.0 2.2 0.9 1.1 1.67 YOR259C 1.0 0.8 1.8 1.2 1.3 1.4 0.9 1.5 2.33 YOR261C 2.1 0.9 2.5 1.8 1.3 2.0 1.0 1.9 2.80 YOR288C 1.4 1.4 2.4 0.8 1.8 1.4 1.5 1.6 0.79 YPL109C −0.2 0.9 1.8 1.3 1.3 1.9 1.2 1.2 0.21 YPL149W 1.2 0.9 2.3 1.0 0.8 1.2 2.2 2.9 1.39 YPL154C 1.8 1.5 3.1 0.8 4.0 1.8 1.6 2.0 3.78 YPR103W 0.9 1.2 2.8 1.8 1.0 1.1 1.2 1.5 1.93 YPR108W 1.8 1.0 2.6 1.0 1.3 1.2 1.0 1.3 2.25 YCL027W 0.9 0.8 1.1 1.2 3.6 1.1 0.7 0.8 0.30 YDR055W 2.2 1.4 3.1 0.9 5.7 3.4 2.0 1.9 1.55 YEL042W 1.6 1.0 0.4 0.6 4.8 0.6 0.7 0.8 1.21 YGR136W 1.3 1.2 1.7 1.1 2.6 2.2 1.3 1.8 1.42 YHR142W 1.1 1.3 1.2 1.2 4.8 1.0 1.3 1.3 1.17 YJL073W 0.5 1.0 1.6 1.1 2.6 0.8 1.1 1.0 0.43 YJR004C 0.7 0.8 0.3 0.7 3.2 0.3 0.4 0.4 2.12 YKL039W 1.0 0.9 1.9 0.8 3.1 1.5 1.2 1.3 1.13 YLR250W 1.4 1.0 1.2 2.5 2.6 2.1 1.4 2.2 2.90 YOR181W 1.0 0.8 1.2 0.9 3.4 1.0 1.1 0.6 0.39 YOR198C 1.4 1.5 1.8 1.1 3.8 0.8 1.1 1.5 1.76 YPL089C 0.9 0.7 1.3 0.8 2.6 0.9 1.5 1.1 0.37 YBR214W 3.2 1.2 2.1 0.9 5.1 1.3 1.1 1.2 0.51 YDR085C 1.7 1.6 1.1 1.6 3.1 2.3 1.3 1.8 0.37 YDR259C 1.2 1.0 2.0 1.5 2.9 0.9 1.0 0.8 0.28 YDR388W 1.6 0.8 1.7 0.6 2.6 1.0 1.2 1.3 0.99 YDR432W 0.6 0.7 1.4 0.5 2.6 0.6 0.7 0.7 2.38 YDR481C 1.2 0.9 1.5 0.9 3.5 1.3 1.2 1.4 1.43 YDR510W 1.6 1.4 2.0 1.9 2.2 1.5 1.1 1.5 1.57 YGR189C 1.5 1.3 1.2 0.9 9.3 0.6 2.3 1.7 1.51 YIL123W 1.2 0.8 0.4 0.3 4.8 0.7 1.3 1.0 1.67 YIL140W 0.9 1.0 0.5 0.9 3.3 0.6 0.7 1.0 0.62 YKL096W 3.5 0.3 0.1 0.5 2.3 0.4 0.5 0.7 2.04 YLR391W 1.4 1.0 0.9 0.5 3.9 1.3 1.4 0.9 1.72 YMR094W 1.0 0.9 1.4 2.8 6.6 1.0 1.0 1.0 0.23 YMR104C 1.1 1.0 1.5 1.1 2.5 2.3 2.8 1.9 0.51 YMR276W 1.9 1.2 1.9 1.2 3.3 0.9 1.2 0.7 0.47 YOL013C 1.4 1.1 1.8 0.9 2.7 1.3 1.1 1.4 0.65 YOR355W 1.2 0.9 1.1 0.6 3.2 0.8 0.8 0.9 0.98 YCR071C 1.1 1.1 1.3 1.7 1.1 1.5 1.2 1.3 0.96 YDL008W 0.9 1.2 2.0 2.2 0.7 1.3 1.5 1.6 0.95 YDR115W 1.2 0.9 1.1 1.5 0.8 2.2 1.2 1.4 1.50 YER130C 0.9 1.0 1.6 0.8 1.1 0.7 3.0 2.5 1.36 YMR226C 1.4 1.1 1.6 1.6 2.0 1.7 1.6 2.0 2.03 YOR383C 1.4 1.1 1.2 0.6 1.1 3.0 1.4 1.1 0.68 YAR010C 0.9 1.0 1.4 1.0 1.8 0.7 1.5 1.0 4.69 YBL043W 1.5 0.9 1.8 1.9 1.8 2.3 2.3 1.8 0.47 YCR004C 1.9 0.8 1.3 3.7 0.8 4.9 1.4 3.5 3.02 YCR088W 1.0 1.3 1.9 0.9 2.8 0.7 1.4 0.9 0.47 YDL238C 1.1 0.9 2.0 1.2 1.3 1.7 1.1 1.3 0.35 YDR084C 0.7 0.7 1.0 1.0 3.9 1.0 2.0 1.3 1.12 YDR104C 1.0 1.1 1.6 1.4 1.4 0.9 0.9 1.0 0.34 YDR315C 1.1 0.6 1.6 1.4 1.5 1.5 1.2 1.2 0.48 YDR358W 1.0 1.1 3.2 1.2 0.9 2.2 1.9 1.9 0.50 YEL066W 1.9 0.8 1.6 1.9 1.0 1.9 1.0 1.1 0.64 YER039C 1.2 0.9 2.1 1.2 1.2 1.8 1.7 1.1 0.42 YER107C 0.7 0.7 0.9 1.1 0.7 0.9 1.1 1.2 0.92 YFL028C 1.3 1.1 1.4 1.6 0.8 1.9 1.2 1.5 1.28 YFL043C 1.1 0.9 1.5 1.5 1.1 2.0 1.5 1.2 0.38 YGL229C 1.1 1.1 1.7 1.0 0.2 1.8 1.1 0.9 0.44 YGR257C 1.2 0.9 2.0 0.9 1.3 1.3 1.1 1.3 0.84 YHR004C 0.8 0.9 1.1 0.8 1.2 2.4 1.4 1.6 0.84 YHR071W 1.8 0.8 2.3 1.6 3.0 1.7 2.6 1.0 0.79 YJL089W 0.6 1.2 1.8 1.8 6.4 1.2 1.2 1.1 0.21 YJL116C 2.9 1.1 4.3 2.6 1.0 1.3 1.2 0.7 1.01 YJR086W 1.0 0.8 0.9 2.2 2.0 1.4 1.4 1.6 1.24 YKL008C 1.5 1.5 1.7 0.8 1.3 2.1 1.4 1.9 2.11 YKL013C 1.1 0.7 1.3 1.4 1.2 1.5 1.6 1.7 1.55 YKL041W 1.2 0.8 1.3 1.3 1.0 2.5 1.1 1.3 0.91 YKL139W 1.4 0.8 1.6 1.0 1.0 1.3 1.9 0.8 0.62 YKR014C 1.1 1.1 1.5 1.8 1.4 2.4 1.0 1.7 2.05 YLR093C 1.0 1.0 1.3 1.3 0.9 2.4 1.7 3.2 1.90 YLR118C 1.2 1.0 1.4 1.5 0.8 3.5 1.3 1.9 1.17 YLR251W 4.1 0.8 1.7 1.3 0.8 2.5 2.1 3.8 0.78 YMR027W 1.1 0.9 2.4 0.9 4.0 0.8 1.3 1.2 4.05 YMR262W 1.3 0.8 1.7 0.9 0.3 1.0 1.0 1.2 0.65 YNL214W 0.6 0.8 1.2 1.7 0.9 2.0 1.1 1.2 0.47 YOR149C 1.0 0.9 1.3 0.9 1.3 1.1 1.0 1.2 0.76 YOR165W 1.3 0.7 0.9 0.8 0.8 1.0 0.9 1.0 1.03 YOR285W 2.3 0.9 2.1 1.6 2.0 2.9 2.3 3.3 2.62 YOR367W 1.4 0.5 0.8 1.5 1.1 1.3 1.4 1.4 0.60 YPL018W 1.3 1.1 2.2 1.3 0.9 0.8 1.3 0.8 0.22 YPL203W 1.5 0.9 1.5 1.0 0.6 2.3 1.3 1.7 0.79 YPL255W 0.7 0.6 0.6 0.7 0.6 0.7 0.8 0.7 0.55 YPR073C 0.9 0.8 1.4 1.5 0.8 1.8 1.4 1.8 1.55 YDR518W 1.0 1.5 1.8 0.8 2.5 1.7 1.4 1.6 0.93 YOR381W 2.6 1.1 1.7 0.8 0.6 2.5 0.8 0.9 0.38 YBR109C 1.5 1.4 2.0 2.0 1.4 1.9 1.4 1.9 2.15 YBR201W 1.1 1.7 1.9 1.1 1.6 1.5 1.8 1.6 0.75 YDR041W 1.2 0.8 0.9 1.4 1.0 2.4 1.5 2.5 1.85 YER136W 1.7 0.9 1.3 0.8 1.2 1.6 1.3 1.7 2.31 YER159C 1.6 0.9 0.9 1.1 2.2 1.1 1.6 1.9 0.99 YJL030W 1.4 1.0 1.4 2.1 1.5 1.9 1.3 1.5 0.87 YJR029W 0.6 1.0 2.1 1.1 1.8 0.7 0.8 1.1 5.84 YJR099W 1.3 0.7 1.5 2.1 0.5 2.0 1.1 1.7 0.94 YJR122W 2.4 0.9 1.3 1.4 0.8 1.9 1.0 1.1 0.43 YJR125C 1.1 0.9 1.5 1.1 1.3 2.0 1.2 1.4 0.90 YKL190W 1.5 0.9 1.3 1.7 1.4 1.8 1.3 1.3 1.14 YLL051C 0.7 1.1 1.3 0.8 1.2 0.8 1.0 1.0 0.81 YLR090W 1.0 0.8 1.7 1.0 0.8 1.9 0.8 1.0 0.67 YMR051C 1.1 0.9 1.3 1.2 1.7 1.0 1.8 1.2 3.91 YMR139W 1.3 0.9 1.6 1.3 0.9 2.3 1.1 2.0 0.89 YNL015W 2.1 2.8 3.9 1.6 1.4 5.3 3.0 5.2 1.03 YNL079C 1.3 1.2 1.8 1.0 1.5 1.4 1.0 1.9 3.26 YNL223W 1.3 1.3 2.0 1.2 1.0 2.1 1.0 1.5 0.34 YNR007C 0.7 0.9 1.5 1.5 0.6 2.0 1.4 1.6 0.49 YNR035C 1.5 1.1 1.7 1.0 1.3 1.6 1.4 1.8 1.60 YOL016C 1.3 1.4 3.0 0.7 0.5 1.6 4.3 3.8 2.10 YOL104C 1.2 0.8 0.6 2.2 1.3 0.5 1.1 0.9 0.32 YPR107C 1.2 0.7 1.4 1.7 1.0 1.4 1.2 1.5 0.81 YOL152W 5.9 0.8 0.5 0.4 0.8 1.2 1.1 1.2 0.91 YAL007C 2.0 1.3 2.0 1.3 2.5 0.8 1.2 1.5 1.74 YDL043C 3.9 0.9 0.8 1.2 0.8 1.2 0.8 0.8 0.78 YDL212W 2.0 0.8 0.5 1.0 1.1 0.9 1.1 1.7 4.27 YDR183W 1.8 1.1 1.4 1.9 1.4 1.3 0.8 1.0 0.61 YGL089C 2.3 0.4 0.2 1.4 0.9 0.2 0.3 0.6 3.00 YGL096W 1.7 1.1 1.2 1.4 0.8 1.7 1.1 1.1 0.54 YGR006W 1.6 0.8 1.4 1.1 1.2 1.5 0.9 1.0 0.40 YHL034C 2.2 0.8 1.6 1.0 1.4 1.6 1.2 1.5 2.11 YHR163W 2.9 0.7 1.1 1.5 0.7 1.2 1.1 1.2 1.71 YIR024C 6.3 1.1 1.6 2.6 0.9 2.2 0.9 1.4 0.75 YKL070W 10.4 0.6 1.0 2.2 0.8 0.9 1.0 0.9 0.29 YLL050C 2.3 0.9 1.8 1.2 1.6 1.3 1.2 2.1 3.43 YLR220W 2.4 0.7 0.5 1.4 0.7 1.1 0.8 0.8 2.28 YLR390W 1.9 1.0 1.1 1.1 0.5 2.0 1.0 0.9 0.51 YOL044W 2.1 0.7 1.3 1.1 0.6 1.3 1.6 1.9 0.65 YOL147C 2.8 0.7 0.8 0.9 0.8 2.4 2.0 1.7 1.09 YDR069C 0.8 0.7 1.3 1.2 1.0 1.3 1.0 1.3 0.33 YER131W 1.0 0.9 0.2 0.8 0.9 0.4 0.9 0.9 5.32 YGR044C 2.1 0.8 1.4 1.0 0.5 3.3 1.1 2.6 1.43 YMR240C 1.4 0.6 0.8 1.1 1.0 1.0 1.1 1.1 0.39 YBR105C 1.1 1.2 1.1 1.7 1.4 1.3 1.3 1.1 0.96 YBR182C 1.5 1.3 1.2 1.2 3.1 1.1 3.4 1.6 0.41 YBR186W 0.9 0.8 0.7 1.1 0.9 1.2 0.7 1.0 0.31 YEL052W 1.7 1.1 1.5 1.1 0.7 2.1 0.9 1.0 0.90 YER098W 1.4 1.0 1.1 1.3 0.9 1.7 1.2 1.5 0.35 YGL240W 0.9 0.8 1.7 1.3 1.1 1.0 1.2 0.8 0.48 YGR067C 1.0 0.7 1.0 0.9 1.2 1.7 1.2 1.0 0.11 YGR133W 1.6 0.9 1.2 1.4 1.0 1.5 1.0 1.0 0.35 YHR124W 1.1 1.2 1.7 2.7 0.8 1.8 1.3 1.1 0.24 YJL103C 1.5 0.8 1.4 1.0 1.3 0.9 1.4 1.2 0.44 YJR036C 1.1 0.9 1.1 1.3 1.8 2.0 0.9 1.2 0.31 YLR216C 1.8 0.7 1.2 1.1 1.2 1.5 1.2 1.3 1.44 YLR389C 0.9 0.8 1.9 0.8 1.0 1.4 1.0 1.0 0.60 YNL128W 0.9 0.9 1.4 1.4 1.1 0.6 0.9 0.9 0.21 YOL133W 1.5 0.6 1.0 1.4 1.3 2.0 1.3 1.3 0.87 YOR133W 1.3 0.8 1.3 1.1 1.8 1.3 1.2 1.2 0.26 YOR227W 1.2 1.0 1.7 1.1 3.7 2.2 0.8 1.3 0.35 YPR015C 1.0 0.7 1.5 1.5 1.6 2.0 1.0 1.0 0.32 YPR086W 1.3 0.8 1.0 1.0 1.3 1.4 1.2 1.2 1.37 YBL056W 0.7 0.9 2.7 0.9 1.0 1.7 1.1 1.5 2.49 YBR026C 1.6 1.2 1.5 1.5 0.7 0.5 0.8 0.9 0.59 YBR123C 1.1 1.0 1.4 1.1 1.0 1.2 0.8 1.0 0.62 YDR099W 1.1 0.9 1.5 0.9 1.9 1.4 1.2 1.7 3.51 YDR177W 1.3 1.2 1.7 2.4 0.8 1.3 1.3 1.5 1.77 YDR392W 1.2 0.8 1.4 1.3 1.1 1.4 1.0 1.2 0.63 YDR394W 1.8 0.6 1.0 1.2 1.1 1.0 1.1 0.8 0.97 YER184C 1.3 0.8 1.6 1.4 1.4 1.2 1.6 2.3 0.29 YFL059W 1.5 1.2 2.3 2.4 0.9 1.6 1.3 1.1 0.57 YGL185C 1.5 1.5 1.7 1.5 0.9 15.8 1.3 1.6 0.23 YHL019C 1.3 0.8 0.8 0.8 1.2 1.3 1.0 1.0 0.55 YHR012W 1.5 0.9 1.7 1.7 1.0 1.0 1.2 1.4 1.11 YHR028C 1.4 0.7 0.6 1.1 1.1 0.7 1.0 1.0 0.92 YHR109W 0.7 1.0 1.4 1.5 0.9 1.3 0.9 1.1 0.22 YHR156C 0.6 0.7 1.0 1.9 1.2 1.4 0.9 1.3 0.47 YIL159W 0.8 0.9 1.5 2.0 1.0 0.7 0.9 0.8 0.29 YJL154C 0.5 0.9 1.6 0.8 1.2 1.2 1.2 1.1 0.62 YJR110W 1.2 0.7 0.9 1.1 1.2 1.1 0.8 1.0 0.58 YKL025C 1.1 0.8 1.3 0.9 1.2 1.1 0.9 1.0 0.54 YKL171W 2.8 1.1 1.5 1.1 1.2 2.1 0.9 1.2 0.45 YKL196C 1.6 1.0 1.8 2.5 1.9 1.9 1.3 2.0 2.41 YKR068C 1.0 1.0 1.1 1.6 0.8 1.4 1.4 1.7 1.72 YLR144C 1.0 0.7 2.3 1.2 1.9 1.7 1.0 1.0 0.44 YML112W 1.0 1.0 1.3 1.8 0.8 0.9 0.8 0.9 0.49 YOL038W 2.0 0.9 1.8 2.1 1.7 1.6 1.1 1.4 1.29 YOR257W 1.0 0.7 0.8 1.5 0.7 1.6 1.1 1.6 0.68 YOR265W 1.3 0.8 1.8 2.5 1.2 1.1 1.0 1.2 0.93 YPL124W 0.9 0.7 0.9 1.6 0.6 0.8 1.3 1.2 0.41 YPR125W 0.9 1.1 1.9 1.6 2.0 0.6 0.8 0.7 0.73 YPR168W 1.2 0.5 1.0 1.1 1.2 1.3 0.9 0.8 0.29 YPR180W 0.5 0.7 1.3 1.2 1.3 1.0 1.0 1.4 0.61 YPR193C 0.1 0.9 1.6 1.6 0.9 1.6 1.1 0.9 0.17 YBR045C 0.4 1.3 1.3 1.0 2.0 0.8 1.1 0.9 1.29 YBR128C 1.3 0.7 1.3 1.4 1.4 2.0 1.2 1.8 0.44 YCL055W 1.4 0.9 0.9 1.8 1.5 0.7 0.8 1.1 0.66 YCR019W 2.0 1.0 1.6 1.2 0.7 1.4 1.0 1.0 0.45 YDL065C 1.4 0.6 0.7 1.4 1.3 1.5 1.1 1.2 1.08 YDL143W 1.3 1.1 1.9 0.9 1.4 0.9 0.8 0.8 1.86 YDL197C 1.1 0.8 1.4 1.1 1.3 0.9 1.3 0.8 0.31 YDL230W 0.9 0.6 1.3 1.0 1.4 1.7 1.0 1.2 0.42 YDR212W 1.8 0.8 2.0 1.0 1.2 0.7 0.6 1.0 2.13 YDR257C 1.3 0.7 1.0 1.0 1.3 1.0 1.1 0.8 0.62 YDR329C 1.0 0.8 1.1 1.1 1.0 1.6 1.2 1.6 0.95 YDR488C 0.4 0.6 1.3 0.8 3.5 0.7 0.9 0.9 0.32 YDR505C 1.0 0.7 1.6 0.9 1.1 1.6 1.0 1.5 0.84 YDR506C 1.1 0.9 0.3 0.5 0.9 0.4 0.6 0.5 1.90 YDR515W 1.0 0.8 0.7 0.8 1.3 0.5 0.7 0.5 1.02 YEL005C 1.6 0.8 1.2 1.7 0.8 3.4 1.1 1.4 0.45 YER048C 1.6 0.8 1.1 1.0 0.6 1.8 1.3 1.6 1.08 YER078C 1.3 1.0 1.5 1.0 0.9 1.0 0.9 0.9 0.49 YER089C 1.2 0.7 1.3 0.6 1.0 0.8 0.7 0.6 0.75 YER100W 1.1 0.8 0.7 0.8 1.0 1.1 1.1 0.7 0.95 YFR051C 1.3 1.2 1.5 0.8 3.0 0.8 1.1 0.9 0.53 YGL093W 1.1 0.6 0.7 0.8 1.4 1.0 0.9 1.2 0.56 YGL105W 1.4 1.1 1.0 1.1 0.9 1.0 0.8 0.9 3.01 YGL166W 1.0 1.1 1.9 1.1 0.9 1.2 2.1 1.9 0.73 YGL215W 0.8 0.7 1.0 0.8 1.0 1.2 0.7 0.9 1.31 YGL216W 0.5 1.0 1.4 1.0 1.1 0.8 1.1 0.9 0.37 YGL221C 1.4 1.1 1.7 1.7 0.7 1.3 1.1 1.4 1.64 YGR186W 1.0 0.6 1.1 1.1 1.3 1.4 1.3 1.2 0.79 YGR270W 0.7 0.8 1.3 0.9 1.6 1.0 0.9 0.9 0.51 YGR274C 0.9 0.7 1.1 0.8 1.2 0.7 1.1 1.0 0.62 YHR082C 0.9 0.7 1.7 0.9 1.4 0.7 1.1 0.9 0.60 YHR160C −0.2 0.8 1.8 1.2 2.1 4.4 1.0 1.5 0.32 YHR171W 1.2 0.8 1.3 1.0 0.7 1.6 1.2 1.5 0.41 YHR205W 0.9 0.9 1.7 0.9 1.5 0.8 0.9 0.8 0.34 YIL062C 1.7 0.8 1.1 2.0 0.9 0.4 1.1 1.1 1.72 YIL075C 0.8 0.8 0.7 0.8 1.6 0.8 0.8 0.8 1.54 YIR009W 1.1 0.7 0.8 1.6 1.1 1.0 1.7 1.0 0.48 YIR018W 1.2 1.1 1.5 1.2 1.5 1.0 1.6 1.1 0.44 YJR091C 1.8 0.8 1.4 0.8 1.4 0.7 1.2 0.9 0.57 YKL079W 1.3 0.9 1.2 0.9 1.1 1.6 1.1 1.2 0.64 YKR102W 3.3 0.8 2.7 1.8 1.1 1.5 1.5 0.9 0.19 YLL054C 0.5 0.7 1.7 1.2 0.9 0.9 1.0 1.0 0.33 YLR200W 1.1 0.9 1.3 2.3 0.9 1.2 1.1 1.5 1.12 YLR248W 1.0 0.7 1.2 0.9 1.2 1.7 1.1 1.7 1.58 YLR266C 1.1 1.0 1.3 1.0 0.8 1.7 0.8 1.4 0.74 YML088W 0.5 1.0 1.3 1.1 1.4 0.8 0.8 0.8 0.58 YMR091C 0.9 0.8 0.9 1.5 0.9 1.3 0.9 1.2 1.03 YMR110C 1.6 0.9 1.8 0.8 0.9 2.7 1.5 2.5 1.63 YMR255W 1.2 0.9 1.1 1.6 1.0 1.3 1.5 2.0 0.97 YNL039W 0.4 0.9 0.8 0.8 1.3 1.3 0.9 1.1 0.61 YNL077W 1.0 0.7 1.5 0.5 0.3 0.6 1.3 1.0 0.78 YNL083W 0.9 0.9 1.2 0.9 0.8 1.8 0.8 1.1 0.37 YNL147W 1.2 0.8 1.0 2.0 1.2 1.7 1.0 1.6 1.32 YNR006W 0.8 0.9 1.6 0.9 1.2 1.1 1.8 1.2 0.40 YNR034W 1.3 0.9 1.4 0.9 1.1 2.3 0.7 1.1 0.64 YNR047W 0.6 0.9 1.5 0.9 1.2 1.5 0.9 1.0 0.44 YOR023C 0.9 1.1 1.9 0.9 1.6 0.8 1.1 0.8 0.37 YOR058C 1.4 0.7 1.7 1.7 1.1 1.6 0.9 1.0 0.31 YOR069W 2.8 0.9 1.1 1.3 1.4 1.5 0.8 1.1 0.69 YOR229W 0.7 0.8 1.3 1.0 1.2 0.9 0.9 1.0 0.58 YOR256C 1.7 0.7 1.6 1.1 1.1 1.5 1.2 1.5 0.53 YPL020C 1.1 0.9 1.1 1.1 1.6 1.2 1.3 1.4 0.91 YPL105C 0.6 0.7 1.0 0.6 1.1 0.5 0.8 0.6 0.80 YPR066W 0.9 0.8 1.4 1.2 0.7 1.6 1.1 1.2 0.41 YPR081C 0.9 1.0 1.4 1.1 1.3 1.8 0.9 1.3 0.34 YPR140W 0.8 0.8 1.3 1.4 1.7 2.4 0.8 1.3 0.47 YPR155C 0.9 0.9 1.3 1.2 0.5 3.4 0.8 1.6 0.40 YPR185W 0.9 0.8 1.7 1.0 1.1 1.3 1.3 1.1 0.68 YBR076W 0.8 0.9 1.9 1.2 1.1 0.5 1.4 1.2 0.36 YDR373W 1.7 0.5 1.0 2.1 1.6 1.4 1.2 1.6 1.08 YFR014C 1.8 0.9 1.3 1.0 0.6 2.3 1.2 2.9 0.94 YHR136C 2.0 1.2 0.3 1.7 0.5 1.3 1.6 2.5 1.33 YIL129C 1.5 1.9 0.9 1.0 1.0 1.3 0.8 0.25 YMR077C 1.5 0.9 0.8 1.6 1.7 2.3 0.9 1.3 0.59 YBR264C 1.0 1.0 0.9 1.6 1.1 1.8 0.9 1.3 0.61 YPL177C 1.4 0.8 0.8 1.3 0.6 1.9 1.2 1.1 0.75 YGL056C 0.0 1.1 0.8 1.1 1.2 1.5 0.9 1.1 0.47 YBL101W-A 1.2 1.1 2.0 1.5 2.1 1.1 1.3 1.2 1.24 YER072W 1.7 1.1 0.6 1.5 0.9 1.1 1.7 1.7 1.69 YMR112C 0.9 1.0 0.9 1.8 0.9 1.4 1.1 1.6 0.57 YJR058C 1.2 0.7 0.8 1.8 0.8 1.2 1.3 1.2 1.00 YML055W 1.4 1.0 1.7 1.9 0.6 1.4 1.2 1.5 1.08 YDR080W 1.2 1.0 2.0 1.1 1.2 1.7 1.2 1.3 0.68 YNR030W 1.2 0.8 1.5 0.6 1.1 0.4 0.9 0.8 1.19 YNL196C 0.7 1.0 2.2 1.2 0.8 2.1 1.1 1.2 0.50 YOR148C 1.3 0.9 1.4 1.4 1.0 1.3 1.0 1.3 1.08 YER029C 0.8 0.9 0.9 1.4 1.1 1.7 0.9 1.3 1.20 YLR360W 0.9 0.9 0.7 1.1 0.8 2.1 1.2 1.4 0.53 YGR239C 1.4 1.0 1.0 1.4 1.3 1.1 1.1 1.3 0.49 YDL229W 1.6 0.9 1.0 1.3 1.2 1.0 1.2 1.1 0.76 YJR027W 1.1 0.8 1.3 1.1 2.3 0.7 0.7 1.1 4.88 YKL198C 1.4 0.7 1.9 6.6 2.6 0.7 1.0 0.8 0.17 YBR031W 0.9 1.0 0.3 0.4 0.9 0.7 1.0 0.8 7.58 YBR118W 1.0 0.8 0.8 0.7 1.6 0.6 1.2 0.9 8.91 YCR106W 1.2 0.8 1.2 0.8 1.3 1.2 1.1 1.2 0.76 YDR012W 0.9 1.2 0.2 0.4 0.8 0.7 1.0 0.7 7.07 YDR134C 1.9 0.6 0.4 0.5 0.8 0.9 0.7 1.1 5.84 YDR276C 1.4 0.9 1.1 1.3 2.2 3.6 1.3 2.4 2.48 YGR279C 0.9 0.7 0.3 0.4 1.3 0.8 1.0 0.8 3.77 YJL059W 1.8 1.0 1.6 1.3 0.9 0.8 1.1 1.0 0.39 YKL056C 1.1 0.8 0.1 0.7 0.9 0.6 0.8 1.2 6.68 YKL097W-A 1.6 0.7 0.2 0.6 2.0 0.8 1.1 1.4 4.01 YNL209W 0.9 0.9 0.5 0.6 0.9 0.3 0.6 0.6 8.06 YNL307C 1.0 1.0 1.0 0.7 0.6 1.0 1.0 1.3 2.79 YPR028W 1.4 0.6 1.7 0.8 0.9 1.3 1.2 1.7 4.06 YPR149W 1.1 0.7 1.4 1.3 1.0 2.2 1.1 1.1 2.65 YAL016W 0.9 0.8 1.4 0.9 1.1 1.1 0.8 1.3 1.00 YBR283C 2.0 0.8 0.8 0.6 1.4 0.9 0.9 0.9 2.62 YBR286W 1.0 1.1 1.8 1.5 1.3 2.6 0.8 1.6 2.98 YCL008C 0.9 0.9 1.0 0.9 1.4 0.6 0.9 0.9 0.47 YCR069W 1.3 1.4 1.6 1.0 2.4 1.2 1.2 1.3 0.97 YDL061C 1.4 1.0 0.1 0.7 1.0 0.6 1.1 1.0 4.40 YDR151C 2.1 0.9 2.8 1.1 0.6 1.2 0.8 1.1 0.96 YDR382W 1.2 0.7 0.1 0.7 1.1 0.4 1.0 1.0 6.40 YDR385W 0.9 0.9 0.3 0.5 0.8 0.3 0.6 0.4 7.27 YDR407C 1.2 1.0 1.3 0.8 1.3 1.0 0.9 0.9 0.52 YGL206C 0.9 0.7 1.1 0.8 1.3 0.6 0.8 1.0 1.04 YGR172C 0.8 0.8 0.7 1.1 1.9 1.0 1.1 1.1 0.94 YIL015W 0.8 0.9 0.8 5.9 1.1 0.8 0.8 1.0 0.17 YIL018W 1.2 0.6 0.0 0.6 0.6 0.4 0.8 0.8 6.27 YJL138C 1.2 0.8 0.3 0.7 0.9 0.6 0.9 1.0 7.38 YJL191W 1.1 1.0 0.9 1.1 0.7 2.2 1.0 1.0 1.86 YJR047C 1.1 0.9 0.9 0.9 0.6 0.8 0.8 0.9 5.29 YJR119C 1.1 0.9 1.2 1.3 1.5 1.0 0.7 0.9 0.30 YJR123W 0.9 0.8 0.1 0.6 1.1 0.4 0.8 0.9 7.84 YJR145C 0.8 0.6 0.0 0.6 0.8 0.5 0.8 0.9 4.82 YLR110C 3.2 0.7 0.5 0.5 1.7 0.8 0.9 1.1 3.99 YLR264W 0.8 1.1 0.3 1.2 1.2 0.5 1.0 1.1 3.91 YLR340W 1.4 0.9 0.1 0.5 1.3 0.2 0.9 0.7 6.55 YLR388W 1.0 0.6 0.1 0.8 0.6 0.5 0.8 1.0 4.48 YMR092C 1.2 0.9 1.7 0.8 1.1 1.2 0.9 1.3 1.43 YMR101C −0.3 0.7 0.8 1.1 1.0 0.9 0.7 0.8 0.16 YNL069C 1.0 0.6 0.1 0.9 1.0 0.3 0.8 0.6 4.03 YNL135C 0.7 0.8 0.9 0.5 1.0 1.4 1.2 1.7 3.05 YOL039W 1.1 0.7 0.1 0.5 0.8 0.4 0.7 0.7 4.94 YOL120C 1.0 0.7 0.1 0.6 0.6 0.3 0.6 0.8 4.42 YOR230W 1.6 1.4 1.5 0.7 0.6 1.6 1.2 1.6 1.76 YOR298W 0.1 0.7 1.1 2.1 1.2 0.5 1.0 0.8 0.41 YPL048W 1.7 1.0 0.9 0.6 1.5 1.3 1.2 1.0 2.11 YPL179W 1.1 1.0 1.3 0.8 1.2 1.4 1.3 1.3 1.38 YPL218W 1.1 1.2 1.0 1.5 1.1 1.7 1.1 1.8 2.98 YPL220W 1.3 0.5 0.1 0.6 0.6 0.5 1.1 1.1 8.33 YPR080W 1.0 1.0 1.3 0.6 1.5 0.6 1.1 1.0 8.03 YPR181C 1.3 1.0 1.7 2.4 1.5 1.6 1.8 1.6 1.84 YBR290W 1.2 1.0 1.7 1.4 0.9 1.3 1.2 2.1 1.34 YCR091W 0.8 1.1 1.3 1.3 0.7 2.7 1.3 1.4 0.22 YFL026W 1.3 0.8 1.1 1.1 1.0 1.0 1.0 1.0 0.27 YOR003W 0.7 0.8 1.0 1.2 2.8 1.3 1.0 1.1 0.30 YCR038C 1.1 0.8 1.0 1.1 0.7 1.0 0.9 1.1 0.31 YDL119C 1.5 0.9 1.1 1.2 0.5 1.2 1.0 1.0 0.77 YDL220C 0.8 1.0 1.6 0.9 1.6 0.8 1.1 0.9 0.24 YDR125C 1.0 0.8 0.9 1.0 0.8 1.7 0.9 1.2 0.35 YDR225W 2.7 0.4 0.2 0.8 0.1 0.8 1.1 1.8 5.54 YER066W 1.5 0.7 0.9 1.1 0.5 3.3 1.1 1.1 0.66 YER076C 0.7 0.7 1.1 0.9 0.8 1.3 1.0 1.0 0.33 YFR006W 1.2 1.0 0.9 0.9 0.8 1.2 0.9 1.3 1.54 YGL208W 1.3 0.8 1.5 0.9 1.8 3.1 0.8 1.3 0.32 YGR023W 2.4 0.9 1.4 1.3 1.1 0.9 1.2 1.5 0.69 YGR108W 0.5 0.4 0.3 0.8 0.2 0.4 0.7 1.0 0.93 YHR195W 1.4 0.9 1.2 1.2 0.7 3.7 1.0 1.5 1.12 YIL050W 0.9 1.0 1.0 1.3 0.6 2.7 1.0 1.1 0.52 YJR050W 0.8 0.8 1.9 1.3 0.9 1.5 0.9 1.1 0.85 YKL093W 0.9 0.9 1.2 1.1 0.8 2.9 0.8 1.0 0.38 YMR053C 1.3 0.9 1.5 1.3 2.4 2.3 1.1 1.6 0.31 YNL139C 0.8 0.5 1.2 0.7 1.4 1.1 1.1 1.0 0.47 YOR122C 1.5 0.8 1.0 1.2 1.6 1.5 1.0 2.2 3.06 YOR312C 0.8 0.7 0.1 0.7 0.7 0.5 1.2 1.0 5.24 YOR327C 2.1 1.0 2.1 1.5 0.9 1.5 2.2 2.1 1.46 YPL001W 1.3 0.7 0.8 1.3 1.3 0.8 0.9 1.2 0.74 YPL230W 3.1 1.0 2.0 1.3 0.7 2.0 1.0 1.6 0.47 YER025W 1.2 0.7 0.6 2.1 0.8 2.6 1.8 2.3 1.96 YHR185C 0.7 0.8 0.4 1.7 1.3 3.2 1.4 3.0 1.64 YIL076W 1.1 0.8 0.8 1.4 1.0 0.8 1.2 2.5 3.73 YMR238W 1.2 1.0 1.5 1.2 2.3 1.4 2.2 2.4 1.36 YBR009C 0.8 0.5 0.4 1.1 0.2 0.4 1.0 2.4 7.00 YBR010W 1.0 0.7 0.4 1.0 0.3 0.8 1.1 2.3 7.25 YCL067C 1.6 1.0 1.4 2.1 2.2 1.7 0.8 2.2 3.15 YCR096C 1.4 1.0 1.0 2.1 2.1 1.8 1.0 2.1 2.34 YDL137W 1.5 1.6 1.7 1.4 1.3 2.3 1.3 2.2 4.95 YDL192W 1.3 1.1 0.9 1.2 1.3 1.3 1.1 2.3 5.57 YDR224C 1.1 0.7 0.5 1.7 0.3 1.1 1.2 2.2 5.62 YDR378C 0.8 0.9 0.8 1.4 0.8 1.0 1.7 2.2 2.40 YMR197C 1.0 1.1 1.5 4.1 1.7 1.9 1.2 2.2 1.20 YOL109W 1.0 0.8 0.5 1.4 1.0 0.8 1.6 2.2 4.13 YPL010W 1.3 1.1 1.1 1.3 1.2 1.3 1.3 2.0 3.25 YHR132C 1.1 0.8 1.2 0.9 1.4 2.3 0.8 1.3 1.52 YJL141C 1.2 0.8 1.4 0.8 0.8 2.2 1.4 1.6 0.94 YKR098C 1.9 1.1 1.4 1.4 0.9 3.9 1.1 1.6 0.55 YLR206W 1.3 0.8 1.4 0.8 2.4 2.3 1.1 1.2 0.72 YAL055W 1.3 1.2 1.5 1.6 1.1 2.6 1.3 1.3 0.62 YAR062W −1.1 0.8 1.2 1.1 1.3 2.4 0.9 1.0 0.32 YBL102W 1.2 0.9 1.7 1.1 1.1 2.0 2.4 1.5 1.26 YBR161W 1.1 0.6 1.0 0.9 1.5 2.1 1.5 2.2 0.72 YCR039C 1.2 0.8 1.0 1.7 1.9 2.1 1.0 2.1 1.73 YDL018C 0.9 0.7 1.0 1.5 1.1 3.1 1.5 1.7 0.84 YDR022C 0.9 0.7 1.3 2.1 1.0 2.1 1.3 1.2 0.47 YDR181C 0.8 0.7 0.7 1.3 1.2 2.0 0.8 1.2 0.48 YGR036C 0.9 1.0 1.3 1.0 0.7 2.0 1.3 1.1 1.12 YGR120C 1.1 0.7 0.5 1.0 1.2 1.9 1.1 1.2 0.36 YGR131W 1.1 0.5 1.4 2.0 0.8 2.6 1.3 1.0 0.41 YGR167W 1.1 1.1 1.6 1.7 1.6 2.8 1.3 1.7 1.79 YHL024W 1.1 1.6 1.6 2.1 2.9 3.8 1.4 1.4 0.58 YJL113W 1.2 0.7 0.9 1.3 1.7 2.1 0.9 1.5 0.41 YJL146W −1.1 1.1 0.8 1.5 1.2 1.8 1.0 1.3 0.30 YJR019C 2.4 1.1 1.4 0.8 1.1 2.6 1.8 1.4 0.33 YJR049C 1.6 1.0 2.1 1.2 1.2 1.7 0.9 1.2 0.44 YLR078C 2.9 1.0 0.8 1.2 0.6 2.2 1.2 1.2 1.02 YNR037C 1.5 0.7 2.0 1.2 0.8 1.9 1.4 1.6 1.34 YOR028C 1.5 0.6 0.8 1.3 1.1 3.7 0.8 1.7 0.78 - The tables show that the expressed mRNA of about 700 of 2400 unknown yeast genes was induced by any one of toxic chemical substances such as heavy metals, agricultural chemicals, surfactants (Table 1), as well as the expressed mRNA of 167 mitochondria-located genes (Table 2), 52 DNA repair genes (Table 3), 161 energy genes (Table 4), 142 transport facilitation genes (Table 5), 90 stress protein genes (Table 6), 142 metabolism genes (Table 7), 60 detoxification genes (Table 8), and 507 genes belonging to other category (Table 9). Here, when the value of the following is 2 or more, then it is considered significant:
- “Intensity” indicated in the rightmost column of Tables 1 to 9 is a value of the level of expressed mRNA of each gene in control cells as divided by the average level of the expressions of the whole genes. When the intensity is low, the error of measurement may be possibly large. The detection is considered more precise when expression magnification (expressed mRNA in the presence of chemical substance/expressed mRNA in the absence of chemical substance) is larger. Yeast gene as used in the processes according to the invention is selected, of which the intensity is preferably 0.3 or more, more preferably 0.5 or more, and of which the expression magnification is preferably 3 or more, more preferably 5 or more.
Claims (17)
1. A process for detecting a toxic substance, which comprises detecting mRNA that is expressed in the presence of a test material by a cell comprising a yeast gene that is selected from a group consisting of the following, or a gene that is homologous to the yeast genes and is derived from other species, wherein the mRNA corresponds to said yeast gene or said homologous gene thereof:
YBR072W, YCR102C, YCR107W, YDL218W, YDL243C, YDR453C, YDR533C, YFL014W, YFL056C, YFL057C, YGR110W, YJR155W, YKL071W, YKR076W, YLL060C, YLR460C, YMR090W, YNL331C, YNL332W, YNL335W, YOL150C, YOL165C, YPL171C, YPR167C, YBL048W, YBL064C, YBL107C, YBR008C, YBR173C, YBR256C, YBR296C, YDL021W, YFL022C, YFL024C, YFL061W, YGL121C, YGL158W, YGR043C, YHR029C, YHR112C, YHR139C, YHR179W, YHR209W, YIR030C, YJR010W, YJR048W, YKL001C, YKL107W, YKR075C, YKR097W, YLL056C, YLR297W, YLR303W, YML087C, YMR096W, YNL274C, YOL151W, YOR226C, YOR338W, YOR391C, YPL280W, YDR406W, YJL153C, YLR346C, YOR049C, YOR153W, YPL088W, YAL034C, YDL124W, YDL174C, YDR476C, YGL156W, YGR035C, YGR157W, YGR213C, YGR281W, YGR284C, YHL047C, YHR043C, YHR044C, YHR054C, YJR073C, YKL165C, YLR008C, YMR315W, YNL211C, YOL031C, YOL101C, YOR303W, YAL005C, YAR031W, YBL005W-A, YBL022C, YBL041W, YBL049W, YBL075C, YBL078C, YBR062C, YBR169C, YBR294W, YCL020W, YCL035C, YCL043C, YCL050C, YCL057W, YCR012W, YCR013C, YCR060W, YDL007W, YDL027C, YDL097C, YDL110C, YDL126C, YDL169C, YDR070C, YDR155C, YDR158W, YDR204W, YDR210W, YDR214W, YDR258C, YDR313C, YDR368W, YDR435C, YER012W, YER037W, YER091C, YER103W, YFL044C, YFR003C, YFR010W, YFR020W, YFR024C, YFR044C, YFR053C, YGL006W, YGL048C, YGL062W, YGL141W, YGL157W, YGL163C, YGL180W, YGL184C, YGR010W, YGR028W, YGR032W, YGR048W, YGR124W, YGR135W, YGR142W, YGR161C, YGR192C, YGR197C, YGR201C, YGR212W, YGR231C, YGR244C, YGR254W, YGR268C, YHL030W, YHR016C, YHR018C, YHR055C, YHR087W, YHR166C, YIL160C, YIR017C, YJL034W, YJL048C, YJL052W, YJL144W, YJL163C, YJR009C, YJR069C, YJR074W, YJR130C, YJR149W, YKL065C, YKL073W, YKL103C, YKL142W, YKL210W, YKL218C, YKR011C, YKR018C, YKR046C, YKR049C, YLL024C, YLL026W, YLR027C, YLR080W, YLR107W, YLR121C, YLR132C, YLR133W, YLR155C, YLR158C, YLR161W, YLR195C, YLR217W, YLR328W, YLR336C, YLR345W, YLR370C, YLR423C, YML004C, YML092C, YML128C, YML130C, YML131W, YMR040W, YMR118C, YMR214W, YMR251W, YMR297W, YMR322C, YNL036W, YNL055C, YNL071W, YNL094W, YNL134C, YNL155W, YNL160W, YNL239W, YNL241C, YOL005C, YOR020C, YOR027W, YOR037W, YOR059C, YOR120W, YOR134W, YOR152C, YOR173W, YOR289W, YOR362C, YPL240C, YPR030W, YAL008W, YAL023C, YAL060W, YAL062W, YAR009C, YBL101C, YBR006W, YBR046C, YBR052C, YBR053C, YBR056W, YBR099C, YBR137W, YBR139W, YBR149W, YBR170C, YBR177C, YBR203W, YBR207W, YBR212W, YBR239C, YBR284W, YBR293W, YCL018W, YCL033C, YCL040W, YCL049C, YCR062W, YCR067C, YCR082W, YDL010W, YDL020C, YDL024C, YDL054C, YDL095W, YDL100C, YDL115C, YDL144C, YDL198C, YDL223C, YDL245C, YDL246C, YDR001C, YDR032C, YDR058C, YDR072C, YDR127W, YDR168W, YDR169C, YDR188W, YDR231C, YDR261C, YDR264C, YDR272W, YDR293C, YDR304C, YDR330W, YDR403W, YDR411C, YDR427W, YDR436W, YDR497C, YDR511W, YDR516C, YDR519W, YDR545W, YEL012W, YEL030W, YER004W, YER009W, YER021W, YER035W, YER053C, YER079W, YER094C, YER096W, YER125W, YER158C, YER163C, YER175C, YER177W, YER178W, YER185W, YFL006W, YFL010C, YFL016C, YFL029C, YFL030W, YFL031W, YFL032W, YFL038C, YFL041W, YFR004W, YFR047C, YFR050C, YFR052W, YGL011C, YGL013C, YGL037C, YGL047W, YGL053W, YGL091C, YGL094C, YGL127C, YGL150C, YGL199C, YGL207W, YGL248W, YGR008C, YGR037C, YGR055W, YGR101W, YGR130C, YGR154C, YGR194C, YGR221C, YGR232W, YGR248W, YGR253C, YGR256W, YHL008C, YHR027C, YHR053C, YHR057C, YHR111W, YHR138C, YHR161C, YHR164C, YHR169W, YHR174W, YHR176W, YHR199C, YIL010W, YIL034C, YIL041W, YIL045W, YIL087C, YIL107C, YIL142W, YIL155C, YIR034C, YIR036C, YIR037W, YIR038C, YIR039C, YJL001W, YJL031C, YJL035C, YJL053W, YJL057C, YJL066C, YJL068C, YJL082W, YJL099W, YJL102W, YJL151C, YJL152W, YJL161W, YJL164C, YJL171C, YJL172W, YJL210W, YJL219W, YJR008W, YJR045C, YJR046W, YJR106W, YJR117W, YJR137C, YKL007W, YKL026C, YKL035W, YKL091C, YKL104C, YKL117W, YKL145W, YKL146W, YKL151C, YKL152C, YKL153W, YKL193C, YKL195W, YKL213C, YKL215C, YLL028W, YLL039C, YLL058W, YLR054C, YLR103C, YLR120C, YLR136C, YLR149C, YLR152C, YLR178C, YLR259C, YLR299W, YLR324W, YLR327C, YLR348C, YLR350W, YLR356W, YLR362W, YLR387C, YLR429W, YML054C, YML070W, YML100W, YML117W, YML125C, YMR004W, YMR008C, YMR009W, YMR020W, YMR067C, YMR089C, YMR097C, YMR102C, YMR105C, YMR107W, YMR152W, YMR180C, YMR184W, YMR191W, YMR219W, YMR271C, YMR275C, YMR295C, YMR314W, YMR316W, YNL006W, YNL007C, YNL012W, YNL044W, YNL045W, YNL074C, YNL092W, YNL093W, YNL104C, YNL115C, YNL156C, YNL231C, YNL234W, YNL237W, YNL281W, YNL305C, YNL333W, YNR010W, YNR019W, YNR033W, YNR059W, YNR068C, YNR069C, YOL032W, YOL036W, YOL047C, YOL071W, YOL082W, YOL083W, YOL117W, YOL119C, YOL126C, YOL131W, YOL153C, YOL162W, YOL163W, YOL164W, YOR019W, YOR035C, YOR036W, YOR099W, YOR117W, YOR124C, YOR130C, YOR132W, YOR157C, YOR185C, YOR197W, YOR259C, YOR261C, YOR273C, YOR288C, YOR332W, YOR336W, YOR347C, YPL017C, YPL087W, YPL106C, YPL109C, YPL149W, YPL154C, YPL196W, YPL206C, YPL222W, YPR023C, YPR024W, YPR026W, YPR067W, YPR103W, YPR108W, YPR151C, YAL012W, YBR029C, YBR222C, YCL009C, YCL027W, YCL064C, YCR098C, YDL222C, YDR055W, YDR077W, YDR502C, YEL001C, YEL042W, YER026C, YER106W, YGR136W, YGR138C, YHR137W, YHR142W, YIL023C, YIL153W, YJL073W, YJR004C, YJR054W, YKL039W, YKL086W, YKL163W, YKR091W, YLR109W, YLR194C, YLR250W, YMR095C, YMR189W, YNL106C, YNL169C, YNL322C, YOR181W, YOR198C, YOR208W, YOR247W, YPL089C, YAL038W, YAL053W, YBR023C, YBR214W, YBR295W, YCR048W, YDL072C, YDL204W, YDR085C, YDR098C, YDR259C, YDR380W, YDR388W, YDR391C, YDR432W, YDR481C, YDR510W, YER069W, YGL022W, YGL126W, YGL209W, YGL255W, YGR189C, YGR282C, YHL035C, YHR030C, YIL022W, YIL024C, YIL117C, YIL123W, YIL140W, YIL154C, YJL088W, YJL108C, YJL149W, YJL159W, YJL186W, YJR148W, YKL096W, YLR180W, YLR273C, YLR300W, YLR307W, YLR378C, YLR391W, YMR094W, YMR104C, YMR276W, YMR296C, YNL190W, YNL208W, YNL300W, YNR064C, YOL013C, YOL058W, YOR248W, YOR355W, YPL052W, YPL163C, YPR079W, YAR028W, YBR146W, YBR183W, YCL038C, YCR071C, YDL008W, YDR019C, YDR031W, YDR115W, YDR486C, YER038C, YER130C, YFL054C, YGL136C, YGR146C, YGR207C, YHL040C, YIL167W, YJL020C, YKR039W, YLR031W, YLR205C, YMR072W, YMR140W, YMR173W, YMR195W, YMR226C, YNL037C, YNR002C, YOL143C, YOR136W, YOR215C, YOR382W, YOR383C, YPL054W, YPL271W, YPR127W, YAL044C, YAL054C, YAR010C, YAR027W, YAR071W, YBL001C, YBL043W, YBL057C, YBR014C, YBR024W, YBR035C, YBR068C, YBR111C, YBR116C, YBR147W, YBR168W, YBR246W, YBR273C, YCR004C, YCR021C, YCR037C, YCR088W, YDL022W, YDL128W, YDL238C, YDR003W, YDR009W, YDR033W, YDR084C, YDR104C, YDR270W, YDR315C, YDR340W, YDR357C, YDR358W, YDR396W, YDR405W, YDR410C, YDR434W, YDR482C, YDR487C, YDR520C, YDR534C, YDR539W, YEL011W, YEL065W, YEL066W, YER039C, YER044C, YER067W, YER080W, YER107C, YFL020C, YFL028C, YFL043C, YFR015C, YGL001C, YGL008C, YGL068W, YGL073W, YGL104C, YGL113W, YGL154C, YGL167C, YGL229C, YGL242C, YGL249W, YGL253W, YGR052W, YGR060W, YGR065C, YGR106C, YGR111W, YGR220C, YGR257C, YHL023C, YHL048W, YHR004C, YHR037W, YHR071W, YHR092C, YHR190W, YIL007C, YIL033C, YIL070C, YIL088C, YIL111W, YIR002C, YIR016W, YIR035C, YIR043C, YJL012C, YJL083W, YJL089W, YJL116C, YJL131C, YJL132W, YJL196C, YJR061W, YJR086W, YJR142W, YJR161C, YKL008C, YKL013C, YKL041W, YKL067W, YKL138C, YKL139W, YKL150W, YKL175W, YKR006C, YKR014C, YKR070W, YLL023C, YLR023C, YLR093C, YLR118C, YLR142W, YLR225C, YLR241W, YLR251W, YLR252W, YLR270W, YML030W, YML110C, YMR021C, YMR027W, YMR148W, YMR181C, YMR262W, YMR272C, YMR298W, YNL011C, YNL130C, YNL214W, YNL259C, YOL129W, YOR042W, YOR052C, YOR137C, YOR149C, YOR165W, YOR270C, YOR285W, YOR367W, YPL018W, YPL156C, YPL186C, YPL203W, YPL216W, YPL255W, YPR006C, YPR073C, YPR098C, YBR050C, YBR145W, YBR299W, YDR518W, YEL020C, YFL062W, YGL039W, YGL134W, YJL217W, YJR159W, YLR126C, YNL249C, YNL284C, YNL336W, YOL157C, YOR344C, YOR381W, YPL265W, YPR124W, YBR074W, YBR109C, YBR126C, YBR201W, YCR005C, YDL248W, YDR041W, YDR105C, YDR268W, YDR452W, YEL075C, YER046W, YER050C, YER136W, YER159C, YGL250W, YGR019W, YGR042W, YGR053C, YGR066C, YGR247W, YGR255C, YGR295C, YHL044W, YHR145C, YIL058W, YIL065C, YIL083C, YIL098C, YIL172C, YJL030W, YJL185C, YJL213W, YJR029W, YJR099W, YJR122W, YJR125C, YKL190W, YKR020W, YLL025W, YLL051C, YLR043C, YLR090W, YLR100W, YLR108C, YLR290C, YML068W, YMR051C, YMR139W, YMR178W, YMR193W, YNL015W, YNL079C, YNL122C, YNL223W, YNL285W, YNL293W, YNR007C, YNR035C, YNR061C, YOL016C, YOL104C, YOR220W, YOR221C, YOR374W, YPL123C, YPR077C, YPR107C, YPR147C, YBR093C, YBR196C, YEL041W, YEL047C, YER023W, YER119C, YFL055W, YGR209C, YIL124W, YKL187C, YLL055W, YMR318C, YOL152W, YAL007C, YBR067C, YBR115C, YBR285W, YBR292C, YDL043C, YDL123W, YDL131W, YDL168W, YDL212W, YDR056C, YDR132C, YDR154C, YDR183W, YDR216W, YDR253C, YDR295C, YDR494W, YDR513W, YEL072W, YER045C, YER061C, YER181C, YFL052W, YFL058W, YFR030W, YGL089C, YGL096W, YGL114W, YGL193C, YGL202W, YGL204C, YGL259W, YGR006W, YGR070W, YGR088W, YHL034C, YHL036W, YHR048W, YHR104W, YHR163W, YIL060W, YIL136W, YIR024C, YJL036W, YJL045W, YJL060W, YJL101C, YJL155C, YJR085C, YJR109C, YJR156C, YKL070W, YKL161C, YKL221W, YKR071C, YLL009C, YLL050C, YLR092W, YLR145W, YLR156W, YLR163C, YLR220W, YLR280C, YLR311C, YLR390W, YML116W, YMR034C, YMR038C, YMR081C, YMR250W, YNL240C, YNL260C, YNL277W, YNR074C, YOL044W, YOL084W, YOL147C, YOL159C, YOR184W, YOR228C, YOR255W, YPL223C, YPR160W, YDL182W, YBR047W, YBR054W, YBR291C, YDR069C, YER124C, YER131W, YGR044C, YIL094C, YKR007W, YMR240C, YNR050C, YOR007C, YAL015C, YBL065W, YBR105C, YBR182C, YBR186W, YBR244W, YBR272C, YCL069W, YDL025C, YDL059C, YDL085W, YDL113C, YDL244W, YDR018C, YDR054C, YDR202C, YDR223W, YDR350C, YDR353W, YDR374C, YDR512C, YEL052W, YEL070W, YER098W, YFR017C, YGL046W, YGL067W, YGL098W, YGL117W, YGL146C, YGL240W, YGR011W, YGR067C, YGR133W, YGR153W, YGR223C, YHR116W, YHR124W, YIL097W, YIL168W, YJL103C, YJL221C, YJR036C, YJR095W, YKL085W, YKL133C, YKL162C, YKL188C, YKL217W, YKR061W, YKR105C, YLL062C, YLR174W, YLR216C, YLR247C, YLR260W, YLR267W, YLR389C, YML007W, YMR041C, YMR177W, YMR253C, YNL009W, YNL117W, YNL128W, YNL183C, YNR073C, YOL133W, YOL158C, YOR133W, YOR225W, YOR227W, YPL161C, YPL166W, YPL202C, YPL224C, YPR015C, YPR086W, YPR201W, YAL061W, YAL067C, YAR007C, YBL033C, YBL056W, YBL086C, YBR026C, YBR073W, YBR101C, YBR117C, YBR123C, YBR213W, YBR269C, YBR280C, YCR036W, YDL132W, YDL149W, YDL200C, YDL234C, YDL242W, YDR099W, YDR177W, YDR256C, YDR392W, YDR394W, YDR531W, YEL071W, YER014W, YER042W, YER090W, YER184C, YFL059W, YFR042W, YFR046C, YFR049W, YGL026C, YGL058W, YGL185C, YGL227W, YGL252C, YGL254W, YGR089W, YGR112W, YGR134W, YGR276C, YHL019C, YHR012W, YHR017W, YHR028C, YHR106W, YHR109W, YHR156C, YIL036W, YIL046W, YIL143C, YIL152W, YIL159W, YIL164C, YJL071W, YJL094C, YJL154C, YJR056C, YJR072C, YJR110W, YJR139C, YKL025C, YKL034W, YKL064W, YKL171W, YKL196C, YKR012C, YKR068C, YKR069W, YLL001W, YLL057C, YLL061W, YLR064W, YLR070C, YLR099C, YLR144C, YLR157C, YLR160C, YLR164W, YLR364W, YLR421C, YML032C, YML042W, YML112W, YML118W, YMR114C, YMR115W, YMR258C, YNL181W, YNL191W, YNL212W, YNL213C, YNL250W, YNL265C, YNL312W, YNR032W, YOL038W, YOL049W, YOL064C, YOR088W, YOR155C, YOR257W, YOR265W, YOR377W, YOR386W, YPL031C, YPL113C, YPL124W, YPL151C, YPL249C, YPL260W, YPL274W, YPR048W, YPR061C, YPR093C, YPR125W, YPR158W, YPR168W, YPR169W, YPR174C, YPR180W, YPR193C, YPR200C, YAL014C, YAL017W, YAL049C, YBL019W, YBL058W, YBR001C, YBR013C, YBR018C, YBR037C, YBR045C, YBR051W, YBR063C, YBR128C, YBR129C, YBR204C, YBR241C, YBR255W, YBR281C, YCL044C, YCL055W, YCR014C, YCR019W, YCR024C, YCR105W, YDL065C, YDL089W, YDL143W, YDL173W, YDL193W, YDL197C, YDL206W, YDL230W, YDL233W, YDR040C, YDR071C, YDR078C, YDR109C, YDR140W, YDR194C, YDR212W, YDR221W, YDR257C, YDR271C, YDR287W, YDR294C, YDR316W, YDR329C, YDR338C, YDR369C, YDR421W, YDR425W, YDR485C, YDR488C, YDR504C, YDR505C, YDR506C, YDR515W, YEL005C, YEL037C, YEL044W, YER017C, YER048C, YER052C, YER078C, YER089C, YER092W, YER100W, YER162C, YER182W, YFL021W, YFL042C, YFR045W, YFR051C, YFR056C, YGL040C, YGL041C, YGL045W, YGL057C, YGL093W, YGL105W, YGL125W, YGL166W, YGL181W, YGL183C, YGL215W, YGL216W, YGL221C, YGL223C, YGR007W, YGR029W, YGR155W, YGR156W, YGR186W, YGR198W, YGR210C, YGR211W, YGR237C, YGR250C, YGR258C, YGR266W, YGR270W, YGR274C, YGR277C, YHL021C, YHL037C, YHL038C, YHR082C, YHR083W, YHR134W, YHR160C, YHR171W, YHR180W, YHR205W, YIL062C, YIL072W, YIL075C, YIL099W, YIL108W, YIL165C, YIL170W, YIR009W, YIR018W, YIR031C, YIR032C, YJL032W, YJL049W, YJL128C, YJL165C, YJR044C, YJR052W, YJR090C, YJR091C, YJR103W, YJR104C, YJR153W, YKL059C, YKL079W, YKL090W, YKL094W, YKL192C, YKL209C, YKR052C, YKR102W, YKR106W, YLL054C, YLR025W, YLR097C, YLR200W, YLR226W, YLR248W, YLR266C, YLR392C, YLR427W, YML013W, YML029W, YML041C, YML051W, YML078W, YML079W, YML088W, YML099C, YMR056C, YMR068W, YMR091C, YMR110C, YMR160W, YMR186W, YMR255W, YNL005C, YNL026W, YNL039W, YNL063W, YNL064C, YNL077W, YNL083W, YNL147W, YNL176C, YNL194C, YNL253W, YNL257C, YNL261W, YNL264C, YNL276C, YNR006W, YNR034W, YNR047W, YNR051C, YNR071C, YOL065C, YOL067C, YOR005C, YOR008C, YOR022C, YOR023C, YOR058C, YOR069W, YOR087W, YOR138C, YOR229W, YOR256C, YOR267C, YPL005W, YPL020C, YPL022W, YPL105C, YPL147W, YPL150W, YPL152W, YPL164C, YPL168W, YPL180W, YPL188W, YPL194W, YPR025C, YPR047W, YPR049C, YPR066W, YPR081C, YPR134W, YPR140W, YPR148C, YPR155C, YPR172W, YPR185W, YAL018C, YAR064W, YBR012C, YBR076W, YBR287W, YDR043C, YDR250C, YDR373W, YFR014C, YGL191W, YGR180C, YHR136C, YJL026W, YJL037W, YLR038C, YNL058C, YOR031W, YGR087C, YIL166C, YHR008C, YIL129C, YGL256W, YJR030C, YMR077C, YBR264C, YPL177C, YKR040C, YGL056C, YDR128W, YGR139W, YBL101W-A, YOR253W, YOL026C, YDR278C, YHR095W, YCL042W, YNL200C, YPL221W, YLR415C, YMR058W, YPR037C, YER072W, YML028W, YOR325W, YAL039C, YMR112C, YJR107W, YGL088W, YJR058C, YNL142W, YDR090C, YMR071C, YBL093C, YGR293C, YML055W, YDL017W, YDL210W, YGL055W, YCL025C, YDR080W, YDL181W, YNR030W, YJL017W, YIL127C, YDR281C, YDR366C, YFR026C, YJL212C, YPL215W, YEL019C, YBR132C, YHL018W, YNL196C, YPL038W, YAR047C, YPL262W, YHL006C, YPL225W, YBR124W, YOR148C, YKR053C, YBL044W, YER029C, YLR360W, YCL056C, YCR007C, YGR239C, YNL256W, YPR146C, YLR377C, YKL097C, YBR066C, YLR338W, YDL229W, YBR253W, YJR027W, YKL198C, YBL030C, YBR031W, YBR118W, YBR162C, YBR221C, YCR024C-A, YCR106W, YDL046W, YDR012W, YDR133C, YDR134C, YDR276C, YDR342C, YDR343C, YEL027W, YEL034W, YGR038W, YGR243W, YGR279C, YHR094C, YHR105W, YHR175W, YHR181W, YIL056W, YIL162W, YJL059W, YJL097W, YJL158C, YJR105W, YKL051W, YKL056C, YKL097W-A, YKL100C, YKL141W, YKR066C, YLR134W, YLR258W, YLR339C, YML058W, YMR083W, YMR203W, YNL209W, YNL307C, YOL030W, YOR178C, YPL028W, YPR028W, YPR113W, YPR149W, YPR150W, YPR183W, YAL016W, YBL099W, YBL100C, YBR011C, YBR096W, YBR100W, YBR127C, YBR283C, YBR286W, YCL008C, YCL058C, YCR030C, YCR034W, YCR069W, YDL015C, YDL023C, YDL061C, YDL086W, YDR038C, YDR039C, YDR050C, YDR151C, YDR178W, YDR233C, YDR284C, YDR298C, YDR345C, YDR359C, YDR382W, YDR385W, YDR400W, YDR407C, YDR538W, YEL024W, YEL033W, YEL063C, YER057C, YER081W, YER120W, YFL011W, YGL012W, YGL206C, YGR022C, YGR026W, YGR082W, YGR107W, YGR172C, YGR191W, YGR204W, YGR260W, YHL005C, YHL046C, YHR025W, YHR026W, YHR123W, YHR126C, YHR143W, YIL011W, YIL015W, YIL018W, YIL157C, YIR041W, YJL016W, YJL121C, YJL133W, YJL138C, YJL191W, YJR018W, YJR047C, YJR077C, YJR119C, YJR121W, YJR123W, YJR143C, YJR145C, YKL060C, YKL147C, YKL148C, YKL157W, YKL164C, YKL169C, YKR033C, YLL041C, YLL064C, YLR041W, YLR044C, YLR056W, YLR058C, YLR081W, YLR089C, YLR110C, YLR177W, YLR264W, YLR284C, YLR304C, YLR340W, YLR354C, YLR372W, YLR388W, YML022W, YMR007W, YMR011W, YMR015C, YMR092C, YMR101C, YMR156C, YMR205C, YMR215W, YMR261C, YMR323W, YNL069C, YNL135C, YNL195C, YNR076W, YOL039W, YOL073C, YOL086C, YOL120C, YOL156W, YOL161C, YOR002W, YOR009W, YOR010C, YOR085W, YOR108W, YOR128C, YOR129C, YOR142W, YOR161C, YOR176W, YOR230W, YOR298W, YPL004C, YPL036W, YPL048W, YPL057C, YPL059W, YPL061W, YPL135W, YPL179W, YPL218W, YPL220W, YPL246C, YPL272C, YPR063C, YPR080W, YPR181C, YBR290W, YCR010C, YCR091W, YDL107W, YDL129W, YDR066C, YDR529C, YFL026W, YGL018C, YGL059W, YNL144C, YOR003W, YAL037W, YAR023C, YBR003W, YBR020W, YBR044C, YBR091C, YBR185C, YBR282W, YCR015C, YCR038C, YCR043C, YDL119C, YDL146W, YDL220C, YDR057W, YDR123C, YDR125C, YDR222W, YDR225W, YDR277C, YDR286C, YDR347W, YDR408C, YDR438W, YDR479C, YDR483W, YEL039C, YEL057C, YEL073C, YER066W, YER076C, YER084W, YER121W, YER189W, YFL017C, YFL046W, YFR006W, YFR008W, YGL115W, YGL208W, YGL214W, YGL218W, YGR021W, YGR023W, YGR024C, YGR064W, YGR076C, YGR096W, YGR108W, YGR174C, YGR182C, YGR236C, YGR288W, YHL042W, YHR195W, YHR210C, YIL006W, YIL012W, YIL028W, YIL050W, YIL057C, YIL089W, YIL102C, YIL113W, YIL122W, YJL100W, YJL169W, YJL199C, YJR039W, YJR050W, YJR101W, YKL003C, YKL016C, YKL061W, YKL093W, YKL121W, YKL160W, YKL170W, YKL194C, YKR034W, YKR067W, YLR006C, YLR016C, YLR030W, YLR036C, YLR112W, YLR125W, YLR128W, YLR204W, YLR211C, YLR233C, YLR257W, YLR288C, YLR326W, YLR334C, YLR395C, YLR408C, YLR414C, YLR444C, YML050W, YML107C, YML120C, YMR031C, YMR053C, YMR073C, YMR162C, YMR204C, YMR206W, YMR284W, YNL010W, YNL025C, YNL127W, YNL139C, YNL217W, YOL116W, YOL118C, YOR053W, YOR100C, YOR103C, YOR122C, YOR150W, YOR187W, YOR251C, YOR312C, YOR327C, YOR348C, YOR352W, YOR388C, YOR394W, YPL001W, YPL033C, YPL066W, YPL148C, YPL230W, YPL275W, YPL276W, YPR005C, YPR014C, YPR192W, YPR194C, YBR005W, YER025W, YFL027C, YGL080W, YGL205W, YHL028W, YHR185C, YIL076W, YJL166W, YLR046C, YMR035W, YMR238W, YMR252C, YNL192W, YNL202W, YOL108C, YOR385W, YPR165W, YAR033W, YBL038W, YBR009C, YBR010W, YBR151W, YCL067C, YCR096C, YDL137W, YDL192W, YDR073W, YDR086C, YDR224C, YDR377W, YDR378C, YER015W, YGL187C, YHR162W, YJL167W, YJL216C, YKR009C, YLR165C, YMR197C, YNL157W, YOL002C, YOL109W, YOR180C, YPL010W, YPL233W, YBR036C, YDR297W, YGR149W, YGR224W, YNL043C, YPL067C, YPL170W, YCR046C, YDR387C, YFL050C, YGL051W, YHR132C, YIL112W, YJL141C, YKR098C, YLR052W, YLR206W, YML129C, YNL203C, YNR014W, YOL043C, YOL096C, YPR184W, YAL028W, YAL055W, YAR062W, YBL095W, YBL102W, YBR122C, YBR157C, YBR161W, YBR251W, YBR298C, YCR039C, YCR083W, YDL018C, YDL067C, YDL078C, YDL091C, YDL215C, YDL216C, YDR022C, YDR067C, YDR079W, YDR181C, YDR186C, YDR196C, YDR262W, YDR306C, YDR319C, YER188W, YGL004C, YGL035C, YGR036C, YGR062C, YGR120C, YGR131W, YGR141W, YGR167W, YGR287C, YHL024W, YHR080C, YHR097C, YIL077C, YJL046W, YJL070C, YJL096W, YJL113W, YJL146W, YJL180C, YJR019C, YJR049C, YKR058W, YLL005C, YLR078C, YLR151C, YLR271W, YLR295C, YLR351C, YLR375W, YMR023C, YMR025W, YMR135C, YMR210W, YMR267W, YMR278W, YMR293C, YNL073W, YNR037C, YNR040W, YNR072W, YOR028C, YOR316C, YOR328W, YOR363C, YPL039W, YPL040C, YPL099C, YPL107W, YPL134C, YPL138C, and YPL140C.
2. The process according to claim 1 , wherein the yeast gene belongs to a category of unknown yeast genes.
3. The process according to claim 1 , wherein the yeast gene belongs to a category of mitochondria genes.
4. The process according to claim 1 , wherein the yeast gene belongs to a category of DNA repair genes.
5. The process according to claim 1 , wherein the yeast gene belongs to a category of energy genes.
6. The process according to claim 1 , wherein the yeast gene belongs to a category of transport facilitation genes.
7. The process according to claim 1 , wherein the yeast gene belongs to a category of stress protein genes.
8. The process according to claim 1 , wherein the yeast gene belongs to a category of metabolism genes.
9. The process according to claim 1 , wherein the yeast gene belongs to a category of detoxification genes.
10. The process according to any one of claims 1 to 9 , wherein the toxic substance is mutagenic.
11. The process according to any one of claims 1 to 10 , wherein the mRNA is amplified by reverse transcription-PCR, and then detected.
12. The process according to claim 11 , which comprises:
(1) adding a test material to the cell, and incubating the mixture;
(2) extracting mRNA from the cell;
(3) preparing cDNA from the mRNA via reverse transcription using labeled nucleotides; and
(4) hybridizing the cDNA as used as probe with the gene as defined in claim 1 .
13. The process according to claim 12 , wherein step (4) as defined in claim 12 is conducted on a microarray containing the gene as defined in claim 1 .
14. The process according to any one of claims 1 to 10 , wherein the mRNA is detected by northern blotting.
15. The process according to claim 14 , which comprises:
(1) adding a test material to the cell, and incubating the mixture;
(2) extracting mRNA from the cell; and
(3) hybridizing the mRNA with the gene as defined in claim 1 .
16. The process according to claim 15 , wherein step (3) as defined in claim 15 is conducted on a microarray containing the gene as defined in claim 1 .
17. The process according to any one of claims 1 to 10 , wherein the detection of mRNA is conducted by detecting the production of a polypeptide encoded by the gene as defined in claim 1.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/772,057 US20070287155A1 (en) | 2001-08-24 | 2007-06-29 | Processes for detecting toxic substances |
| US12/554,386 US8192962B2 (en) | 2001-08-24 | 2009-09-04 | Processes for detecting toxic substances |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001-255380 | 2001-08-24 | ||
| JP2001255380A JP4475373B2 (en) | 2001-08-24 | 2001-08-24 | Method for detecting toxic substances |
| PCT/JP2002/008494 WO2003018791A1 (en) | 2001-08-24 | 2002-08-23 | Method of detecting toxic substance |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US11/772,057 Division US20070287155A1 (en) | 2001-08-24 | 2007-06-29 | Processes for detecting toxic substances |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US20040248126A1 true US20040248126A1 (en) | 2004-12-09 |
Family
ID=19083356
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US10/487,439 Abandoned US20040248126A1 (en) | 2001-08-24 | 2002-08-23 | Method of detecting toxic substance |
| US11/772,057 Abandoned US20070287155A1 (en) | 2001-08-24 | 2007-06-29 | Processes for detecting toxic substances |
| US12/554,386 Expired - Fee Related US8192962B2 (en) | 2001-08-24 | 2009-09-04 | Processes for detecting toxic substances |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US11/772,057 Abandoned US20070287155A1 (en) | 2001-08-24 | 2007-06-29 | Processes for detecting toxic substances |
| US12/554,386 Expired - Fee Related US8192962B2 (en) | 2001-08-24 | 2009-09-04 | Processes for detecting toxic substances |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US20040248126A1 (en) |
| EP (2) | EP1426438A4 (en) |
| JP (1) | JP4475373B2 (en) |
| WO (1) | WO2003018791A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090246755A1 (en) * | 2003-12-02 | 2009-10-01 | Daikin Industries, Ltd. | Method of examining chemical using gene-disrupted strain |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004357575A (en) * | 2003-06-04 | 2004-12-24 | Daikin Ind Ltd | Circulating culture method for microorganism |
| MX2011003888A (en) * | 2008-10-13 | 2011-05-25 | Wabash National Lp | Foldable mobile storage container. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3931300A (en) * | 1999-03-31 | 2000-10-16 | Rosetta Inpharmatics, Inc. | Methods for identifying pathway-specific reporters and target genes, and uses thereof |
| JP3446042B2 (en) | 2000-02-28 | 2003-09-16 | 独立行政法人産業技術総合研究所 | Microbiological identification of chemicals |
| JP4022610B2 (en) * | 2000-04-07 | 2007-12-19 | 独立行政法人産業技術総合研究所 | Toxicity assessment method for chemical substances |
-
2001
- 2001-08-24 JP JP2001255380A patent/JP4475373B2/en not_active Expired - Lifetime
-
2002
- 2002-08-23 US US10/487,439 patent/US20040248126A1/en not_active Abandoned
- 2002-08-23 WO PCT/JP2002/008494 patent/WO2003018791A1/en not_active Application Discontinuation
- 2002-08-23 EP EP02760722A patent/EP1426438A4/en not_active Withdrawn
- 2002-08-23 EP EP07012706A patent/EP1847601A3/en not_active Withdrawn
-
2007
- 2007-06-29 US US11/772,057 patent/US20070287155A1/en not_active Abandoned
-
2009
- 2009-09-04 US US12/554,386 patent/US8192962B2/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090246755A1 (en) * | 2003-12-02 | 2009-10-01 | Daikin Industries, Ltd. | Method of examining chemical using gene-disrupted strain |
| US8173387B2 (en) | 2003-12-02 | 2012-05-08 | Daikin Industires, Ltd. | Method of examining chemical using gene-disrupted strain |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1847601A2 (en) | 2007-10-24 |
| US8192962B2 (en) | 2012-06-05 |
| WO2003018791A1 (en) | 2003-03-06 |
| EP1847601A3 (en) | 2008-01-16 |
| EP1426438A4 (en) | 2005-01-26 |
| US20100075324A1 (en) | 2010-03-25 |
| JP2003061673A (en) | 2003-03-04 |
| JP4475373B2 (en) | 2010-06-09 |
| US20070287155A1 (en) | 2007-12-13 |
| EP1426438A1 (en) | 2004-06-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Tsuji et al. | The detection of aquatic macroorganisms using environmental DNA analysis—A review of methods for collection, extraction, and detection | |
| Everts et al. | Accurate detection and quantification of seasonal abundance of American bullfrog (Lithobates catesbeianus) using ddPCR eDNA assays | |
| Xing et al. | A review of environmental DNA field and laboratory protocols applied in fish ecology and environmental health | |
| US8192962B2 (en) | Processes for detecting toxic substances | |
| US20100041089A1 (en) | Improved method for detecting chemical substances | |
| EP1921157B1 (en) | Processes for detecting toxic substances | |
| Yarnall et al. | A quantitative competitive polymerase chain reaction assay for the oyster pathogen Perkinsus marinus | |
| JP4022610B2 (en) | Toxicity assessment method for chemical substances | |
| RU2698651C1 (en) | Method for determination of hydrobionts saprobity for assessment of ecological state of water bodies | |
| Schwentner et al. | Genetic differentiation in mountain-dwelling clam shrimp, Paralimnadia (Crustacea: Branchiopoda: Spinicaudata), in eastern Australia | |
| Minter et al. | A rapid and cost‐effective quantitative microsatellite genotyping protocol to estimate intraspecific competition in protist microcosm experiments | |
| US7704692B1 (en) | Process for detecting toxic substances | |
| Day et al. | Use of competitive PCR to detect and quantify Haplosporidium nelsoni infection (MSX disease) in the eastern oyster (Crassostrea virginica) | |
| Hogg et al. | Biodiversity genomics: monitoring restoration efforts using DNA barcoding and environmental DNA | |
| Carreon-Martinez et al. | The use of polymerase chain reaction for the identification of sciaenid eggs | |
| Wares et al. | Re-evaluation of homozygous lethality for EF1A indel polymorphism in Pisaster ochraceus | |
| CN117265080B (en) | Zebra fish gene markers and application thereof in assessing risk of nerve injury caused by environmental pollutants | |
| Heuvel et al. | Molecular approaches to identify exposure and risk to specific environmental pollutants | |
| JP4290438B2 (en) | Toxic substance identification method using DNA microarray method | |
| Ashwini et al. | Chapter-5 Methods and Tools used for the Identification of Plant Parasitic Nematodes | |
| Mok et al. | PhenoMIP: High Throughput Phenotyping of Diverse C. elegans Populations via Molecular Inversion Probes | |
| JP2006174802A (en) | Polynucleotide, probe and dna micro-array for detecting heavy metal-responding gene of soil nematode and evaluation method of soil pollution using soil nematode | |
| CN111926090A (en) | Specific primer, probe and kit for detecting mactra veneriformis in freshwater environment | |
| Cooney | Analyzing toxicants on a chip | |
| CN117143971A (en) | Rapid anopheles sinensis identification kit and identification method based on RAA technology |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AS | Assignment |
Owner name: DAIKIN INDUSTRIES, LTD., JAPAN Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:IWAHASHI, HITOSHI;MOMOSE, YUKO;KITAGAWA, EMIKO;AND OTHERS;REEL/FRAME:015379/0587;SIGNING DATES FROM 20040316 TO 20040323 Owner name: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:IWAHASHI, HITOSHI;MOMOSE, YUKO;KITAGAWA, EMIKO;AND OTHERS;REEL/FRAME:015379/0587;SIGNING DATES FROM 20040316 TO 20040323 |
|
| AS | Assignment |
Owner name: DAIKIN INDUSTRIES, LTD., JAPAN Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY;REEL/FRAME:019276/0574 Effective date: 20070326 |
|
| STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |