US1603877A - Medicinal package - Google Patents

Medicinal package Download PDF

Info

Publication number
US1603877A
US1603877A US31031A US3103125A US1603877A US 1603877 A US1603877 A US 1603877A US 31031 A US31031 A US 31031A US 3103125 A US3103125 A US 3103125A US 1603877 A US1603877 A US 1603877A
Authority
US
United States
Prior art keywords
ampule
stopper
liquid
medicinal
tip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US31031A
Inventor
Smith Arthur Ervin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to US31031A priority Critical patent/US1603877A/en
Application granted granted Critical
Publication of US1603877A publication Critical patent/US1603877A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3277Ampoules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • B01F35/713Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • B01F35/713Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B01F35/7135Opening the seal between the compartments by application of heat
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • B01F35/716Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
    • B01F35/7162A container being placed inside the other before contacting the contents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Description

inventor alike-mu 5 Oct. 19 1926.
A. E. SMITH MEDICINAL PACKAGE Filed May 18 I 1925 Ere-4:.
ARTHUR E. SmiTH Patented Oct. 19, 1926.
UNITED STATES ARTHUR ERVIN SMITH, OF LOS ANGELES, CALIFORNIA.
MEDICINAL PACKAGE.
Application filed Kay 18, 1925. Serial No. 31,031.
This invention relates to a medicinal package or ampule and it has for its object to provide a device of this character of such a nature that the medicinal solution may be made fresh at time of use and injected from the ampule, through the medium of a suitable hypodermic syringe, directly into the patient.
In my co-pending application Serial Number 607,391, filed December 16, 1922, I have disclosed a medicinal package consisting of an ampule containing a body of distilled water and having therein a capsule of paraffin or tablets, of any suitable pharmaceutical preparation, such as an anesthetic for example, the whole being so arranged that the tablets are maintained out of contact with the vehicle or water until the time of use arrives, at which time the ampule is immersed in hot water to cause the parafiin to melt and to permit the tablet to dissolve in the distilled water or any other desirable vehicle.
The importance of having freshly made anesthetic solutions for use in nerve blocking work, has been set forth at length in the specification of my application Serial Number 607,391 and need not be repeated here. It suffices to say that in vcertain classes of work and with certain materials, it is absolutely essential that the solution be freshly made at the time of use in order to avoid disintegration or chemical change of unstable drugs and to avoid deleterious or toxic effects upon the patient.
The ampule constituting the subject matter of the present invention differs from the ampule of my application aforesaid in that it is adapted to be loaded into a syringe after the manner of a cartridge and'has a breakable tip at one end of the ampule and a movable cork or stopper toward the other end of the ampule, the latter being adapted to be engaged by the plunger of the hypodermic syringe to eject the liquid through the broken tip of the ampule and into and through a hypodermic needle.
In my co-pending applications Serial Numbers 31,029 and 31,030, filed on the 18th day of May, 1925,I have illustrated syringes adapted for use in connection with the ampule of the present invention. However, it is to be understood that this application is intended to cover medicinal packages per se since it is manifest from the two applications referred to that it is not limited to use with any one type of syringe.
In the accompanying drawing:
Figure 1 is a side elevation of an ampule :onstructed in accordance with the invenion.
Figure 2 is a longitudinal sectional View therethrough, before being heated in boiling water.
Figure 3 is a longitudinal sectional View therethrough, after being heated, and
Figure 4 is a sectional View after the tip and rear end portions are broken off and the ampule is ready to be charged into a syringe.
In the drawing, wherein like reference characters designate corresponding parts throughout the several figures, 5 designates the body of an ampule, having a reduced end or tip 6. This tip is etched, or cut partially through, as indicated at 7, to render it easy to break away the tip 6 and thus leave an opening through which the contents of the ampule may be ejected.
While I have mentioned distilled Water as constituting one of the ingredients of the medicinal solution, any other liquid may be substituted therefor, if, in the judgment of the physician, this should be done. A stop per 8 which is preferably of rubber and which is preferably provided with a concave front face 9 is disposed to slide in the body of the ampule and confines a body of liquid, such as distilled water for example, in dicated at 10, between itself and the tip 7 and in this body of liquid there is placed a paraffin capsule 11 containing tablets or powder 12 of any character that it is desired to dissolve in the liquid. The rear end of the ampule is preferably closed and hermetically sealed as indicated at 13 and the ampule is nicked, etched, cut or otherwise weakened at 13 to permit of this rear portion being broken away when the time of use arises.
Thus, when placed upon the market the ampule constitutes a hermetically sealed package which protects not only the medicinal ingredients but also its stopper 8 from contamination. When the end 13 is broken away at the time of use, the edge 14 constitutes a surface againstwhich a retaining element of the syringe, not shown, may bear, as illustrated in my co-pending ap plications above referred to. When the parafiin of the capsule is melted, it rises due to the specific gravity, (if the ampule be held in a vertical position at this time), to
the stopper 8 and seats itself in the concave face of the sto per. Then the package is placed in col water, holdin large end up, or is held in water until t e paraffin congeals or hardens and thus, becomes, in effect, a part of the stopper; This stopper in conjunction with the plunger of the syringe constitutes an ejecting piston for the medicinal solution.
While I prefer to make the ampule as a completely sealed ackage, as illustrated in Figure 2 of the rawing, the closed rear end may be omitted if desired and the inner end be left open to roduce a package substantially likethat ilustrated in Figure 4.
The reduced and tapered end of the ampule by which the broken tip 6 is carried, constitutes a wedging element which materially aids in forming a fluid tight connection between the forward end of the ampule and suitable packin members of the syringe, at the time of e ection of the liquid from the ampule.
It is to be understood that the invention is not limited to the precise construction set forth but that it includes within its purview whatever changes fairly come within either the terms or the spirit of the appended claims.
Having described my invention, what I claim is:
1. An ampule of the character described.
comprising a body portion having a breakable tip and a slidable stopper disposed therein, a body of liquid between the stopper and tip and a readil fusible medicine carrying container in sai liquid.
2. An ampule of the character described cbmprising an elongated body portion havcally sealed bothin front and in rear of said stopper, a body of liquid in front of said stopper, an element to be mixed with said body of liquid and a fusible body separating said element from said bod of liquid until fused by the application 0 heat.
5. A structure as recited in claim 4 in combination with weakened portions formed in the body of the ampule in the rear of the stopper and adiacent the front end thereof.
6. An ampule of the character described comprising anelongated body portion having a sto per slidab y disposed therein, said stopper ing of elastic material and having a concave front face, and a readily fusible medicine carrying container in advance of said stopper, the material of which, when fused, seats itself in the concave front face of the stopper and forms a part of said stopper.-
7. An ampule of the character described comprising a body portion, a slidable stoppper disposed therein, a body of liquid within the body portion and in advance of the stopper and a readily fusible medicine carrying container in said liquid.
In testimony whereof I hereunto afiix my signature.
ARTHUR ERVIN SMITH.
US31031A 1925-05-18 1925-05-18 Medicinal package Expired - Lifetime US1603877A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US31031A US1603877A (en) 1925-05-18 1925-05-18 Medicinal package

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31031A US1603877A (en) 1925-05-18 1925-05-18 Medicinal package

Publications (1)

Publication Number Publication Date
US1603877A true US1603877A (en) 1926-10-19

Family

ID=21857284

Family Applications (1)

Application Number Title Priority Date Filing Date
US31031A Expired - Lifetime US1603877A (en) 1925-05-18 1925-05-18 Medicinal package

Country Status (1)

Country Link
US (1) US1603877A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2996223A (en) * 1958-11-21 1961-08-15 Dolezal Fine instruments lubricator with disposable lubricant cartridge
US3157312A (en) * 1961-12-18 1964-11-17 Donald M Kitterman Decoration dispenser and the method of making, filling, and dispensing from the same
WO2005105284A1 (en) * 2004-04-30 2005-11-10 Siemens Aktiengesellschaft Method for the production of a solution, associated arrangement and uses of the method and the arrangement

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2996223A (en) * 1958-11-21 1961-08-15 Dolezal Fine instruments lubricator with disposable lubricant cartridge
US3157312A (en) * 1961-12-18 1964-11-17 Donald M Kitterman Decoration dispenser and the method of making, filling, and dispensing from the same
WO2005105284A1 (en) * 2004-04-30 2005-11-10 Siemens Aktiengesellschaft Method for the production of a solution, associated arrangement and uses of the method and the arrangement
US20070212708A1 (en) * 2004-04-30 2007-09-13 Siemens Aktiengesellschaft Method for the Production of a Solution, Associated Arrangement and Uses of the Method and Arrangement
CN1946473B (en) * 2004-04-30 2010-05-26 西门子公司 Method for the production of a solution, associated arrangement and uses of the method and the arrangement
US8518343B2 (en) 2004-04-30 2013-08-27 Siemens Aktiengesellschaft Method for the production of a solution, associated arrangement and uses of the method and arrangement

Similar Documents

Publication Publication Date Title
US4979941A (en) Device suitable for mixing medication
US3348546A (en) Intermixing syringe
US3757779A (en) Filter syringe
US3115133A (en) Needleless prefilled disposable hypodermic injector
AU670592B2 (en) Injection cartridge arrangement
US2847996A (en) Hypodermic syringe
US3678931A (en) Syringe
US2773591A (en) Vessel with sterile closure for separate storage of at least two substances
US3908654A (en) Dispensing package for a dry biological and a liquid diluent
US3838689A (en) Disposable syringe with slit valve
US4515586A (en) Powder syringe mixing system
JP2009504523A (en) Dual chamber container without bypass
US3552387A (en) Combination syringe and vial
HUT74792A (en) Device for mixing a pharmaceutical composition with another agent
JPS6258745B2 (en)
US2636493A (en) Mixing container for segregated ingredients of therapeutic preparations
WO2017080521A1 (en) Single-needle medicine mixer, dual hard ports, and soft infusion bag
US1967439A (en) Medicament package and process
JP2019536566A5 (en)
US2449968A (en) Hypodermic syringe
US1909591A (en) Method of utilizing hypodermic medicaments, etc.
USRE16836E (en) Hypodermic syringe.
US1603877A (en) Medicinal package
US2028751A (en) Container
US3192925A (en) Disposable syringe device