US1580400A - Composition for the treatment of goiter - Google Patents
Composition for the treatment of goiter Download PDFInfo
- Publication number
- US1580400A US1580400A US28019A US2801925A US1580400A US 1580400 A US1580400 A US 1580400A US 28019 A US28019 A US 28019A US 2801925 A US2801925 A US 2801925A US 1580400 A US1580400 A US 1580400A
- Authority
- US
- United States
- Prior art keywords
- composition
- treatment
- goiter
- grams
- iodine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Definitions
- My invention relates to a composition, which is particularly adaptable for use in the treatment of goiter.
- goiter is considered to be a patholo ical enlargement of the thyroid g1 nd, in which the biological cells of this glan are abnormal to such an'extent that the hysiological internal secretion of the thyroid gland in the last stages of the goiter is prevented, and in all stages, the internal secretion of the thyroid
- a treatment which will revive the internal secretion of the gland will serve to. restore the biological cells to normal condition, decrease the enlargement,.and remove the pathological disturbance.
- r v 4 Thedecrease of the enlar ement and the removal ofthe pathological. isturbancewill be effected by-the revival of the normal flow of the internal secretion oft-he gland, but the treatment which will revive the internal se-.
- cretion will also directly aid the restoration of the biolo 'calcellsto normal condition.
- the fundamental ingr edients whichare designedto aflect'the blological cel-ls'of the thyroid gland in the manner indicated, and remove the pathological disturbance are:
- the distilled water serves as a vehicle for.
- the glycerine also serves as a .sol-
- tary iodine twenty centigrams
- potassium iodide two grams
- guaiacol four grams
- the glycerine is set out as being pure and neutra solvent lmust be firee from any qualities
- the composition is administered by intramuscular 1n ect1ons and on this account, the
- the amount of the mixture which will be injected and The potassium iodide serves to assist the dissolving of the elementary iodine.
- a composition for intra-muscular treatment-of goiter comprising the following ingredients in substantially the proportions I set-'out, to wit: elementary iodine, twenty grams; guaiacol, four grams; distilledwater, fifteen grams; pure neutral glycerine ten grams, J
- a composition for intro-muscular treatment of goiter comprising in substantially V I the proportions set out the following ingredi- 10 e'nts, to wit: elementary iodine, twenty centigrams; potassium iodide,- two grams; guaiacol, four grams; and a vehicle suitable for intro-muscular injection.
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- Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Description
Pate ted A r. 13,1926. v
UNITED STATES PATENT OFFlCE PAULJBOMMARITO, OF DETROIT, MICHIGAN.
' T all whom it may concern:
comrosrrron roB. THE TREATMENT or sense.
so Drawing.
Be it known that I, PA L BOMMARITO, a citizen of theUnited States, residing at Detroit, in the county of Wayne and State of Michigan, have invented a new'and useful I Improvement in a Composition for the gland is disturbed. 20.
-- Treatment of Goiter, of which the following is a specification.
My invention relates to a composition, which is particularly adaptable for use in the treatment of goiter. In medical science, goiter is considered to be a patholo ical enlargement of the thyroid g1 nd, in which the biological cells of this glan are abnormal to such an'extent that the hysiological internal secretion of the thyroid gland in the last stages of the goiter is prevented, and in all stages, the internal secretion of the thyroid It is recognized that a treatment which will revive the internal secretion of the gland, will serve to. restore the biological cells to normal condition, decrease the enlargement,.and remove the pathological disturbance. r v 4 Thedecrease of the enlar ement and the removal ofthe pathological. isturbancewill be effected by-the revival of the normal flow of the internal secretion oft-he gland, but the treatment which will revive the internal se-.
, cretion, will also directly aidthe restoration of the biolo 'calcellsto normal condition.
To provi e a composition which will produce the desired efiect, is an object of the present invention.
In the composition, the ingredients used are: Elementa iodine, potassium iodide, guaiacolgdistille water,=and glycerine.
The fundamental ingr edients whichare designedto aflect'the blological cel-ls'of the thyroid gland in the manner indicated, and remove the pathological disturbance are:
1 elementary iodine, potassium 'iodide, andguaiacol.
v j The distilled water serves as a vehicle for.
f the fundamental ingredients and asa sol:
vent. The glycerine also serves as a .sol-
vent, and tendsto reduce irritation incident to the injection of the composition and con t'rols, tolsome extent, the reactionresulting from .theinjeetion.
' .In' this description,
state.
. These ingredients preferablyfaisedfin' the follow ng prpportions, to wit: element-rh e elementary iodine referred to -is,,the p'u e. iodine"in lcrystal K iodine, potassium iodi e,'gi1aiac ol, in solution .in a vehicle suitable for intra-muscular Application filed May 4, 1925. Serial No. 28,019.
tary iodine, twenty centigrams; potassium iodide, two grams; guaiacol, four grams;
distilled water, fifteen-grams; pure neutral glycerine, ten 'ams.
It will be noted that the glycerine is set out as being pure and neutra solvent lmust be firee from any qualities The composition is administered by intramuscular 1n ect1ons and on this account, the
which would unduly irritate, or infect the person receiving the treatment. The amount of the mixture which will be injected and The potassium iodide serves to assist the dissolving of the elementary iodine.
Whether or not there is any chemical reaction between the ingredients usedg the applicant is at present unable to state. The statement is made, however, that the ingredients used have given very satisfactory results in the treatment of cases of goiter, in various "degrees of development, and the composition set out herein is the result of 8 long and frequent experiments, so that the applicant is convinced that, the three funda- -mental ingredients used are essential and that they have .a co-operative relation in their eifect on the patient treated. This conyiction has arisen from the studied results in many experiments in which one of the fundamentals was omitted and the other two combined. The ex eriments were also carried further in coni ining two of the fundaing'redieits', the result bein vmentalingredients set out-herein with other o thatthe com- I *POSltlOll set out herein-was 'scoveredj to be be the" most efl'eetive,although itwill readily appear to thoseskilied in the practiceflof '-medicine, that slightvariations 1n the proportionate amounts might be had without diminishing, to any great extent, the benefits defivedfmm use-0f the t position,
whatlclaimisz. p v
p 1. A composition for intra muscular treat ment' of goiter, com rising: elementary injection'z" '5 centigrams; potassium iodide, two
2. A composition for intra-muscular treatment-of goiter, comprising the following ingredients in substantially the proportions I set-'out, to wit: elementary iodine, twenty grams; guaiacol, four grams; distilledwater, fifteen grams; pure neutral glycerine ten grams, J
l 3. A composition for intro-muscular treatment of goiter comprising in substantially V I the proportions set out the following ingredi- 10 e'nts, to wit: elementary iodine, twenty centigrams; potassium iodide,- two grams; guaiacol, four grams; and a vehicle suitable for intro-muscular injection.
foregoing specification.
In testimony whereof, I have. signed the "k i
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28019A US1580400A (en) | 1925-05-04 | 1925-05-04 | Composition for the treatment of goiter |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28019A US1580400A (en) | 1925-05-04 | 1925-05-04 | Composition for the treatment of goiter |
Publications (1)
Publication Number | Publication Date |
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US1580400A true US1580400A (en) | 1926-04-13 |
Family
ID=21841096
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US28019A Expired - Lifetime US1580400A (en) | 1925-05-04 | 1925-05-04 | Composition for the treatment of goiter |
Country Status (1)
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US (1) | US1580400A (en) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4297232A (en) * | 1978-01-12 | 1981-10-27 | Samuel Ruben | Glycol-iodine composition and method of preparation |
US5389385A (en) * | 1985-07-31 | 1995-02-14 | Ghent; William R. | Treatment of iodine deficiency diseases |
WO1998043481A1 (en) * | 1997-04-02 | 1998-10-08 | West Agro, Inc. | Stable glycerin iodine concentrate compositions |
US5910318A (en) * | 1991-03-28 | 1999-06-08 | 943038 Ontario Inc. | Treatment of iodine deficiency diseases |
US5955101A (en) * | 1991-03-28 | 1999-09-21 | 943038 Ontario Inc. | Dry starch-iodine pharmaceutical formulations |
US6019970A (en) * | 1985-07-31 | 2000-02-01 | Ghent William R. | Treatment of iodine deficiency diseases |
WO2000018237A1 (en) * | 1998-09-30 | 2000-04-06 | West Agro, Inc. | Stable glycerin iodine concentrate compositions |
US20100266573A1 (en) * | 2007-11-23 | 2010-10-21 | Pharmalundensis Ab | Method and means for obtaining bronchorelaxation |
US20100272814A1 (en) * | 2007-12-19 | 2010-10-28 | Pharmalundensis Ab | Method and means for producing bronchorelaxation |
-
1925
- 1925-05-04 US US28019A patent/US1580400A/en not_active Expired - Lifetime
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4297232A (en) * | 1978-01-12 | 1981-10-27 | Samuel Ruben | Glycol-iodine composition and method of preparation |
US5389385A (en) * | 1985-07-31 | 1995-02-14 | Ghent; William R. | Treatment of iodine deficiency diseases |
US6019970A (en) * | 1985-07-31 | 2000-02-01 | Ghent William R. | Treatment of iodine deficiency diseases |
US5910318A (en) * | 1991-03-28 | 1999-06-08 | 943038 Ontario Inc. | Treatment of iodine deficiency diseases |
US5955101A (en) * | 1991-03-28 | 1999-09-21 | 943038 Ontario Inc. | Dry starch-iodine pharmaceutical formulations |
WO1998043481A1 (en) * | 1997-04-02 | 1998-10-08 | West Agro, Inc. | Stable glycerin iodine concentrate compositions |
US5885620A (en) * | 1997-04-02 | 1999-03-23 | West Agro, Inc. | Stable glycerin iodine concentrate compositions |
AU722057B2 (en) * | 1997-04-02 | 2000-07-20 | West Agro, Inc. | Stable glycerin iodine concentrate compositions |
WO2000018237A1 (en) * | 1998-09-30 | 2000-04-06 | West Agro, Inc. | Stable glycerin iodine concentrate compositions |
US20100266573A1 (en) * | 2007-11-23 | 2010-10-21 | Pharmalundensis Ab | Method and means for obtaining bronchorelaxation |
US20100272814A1 (en) * | 2007-12-19 | 2010-10-28 | Pharmalundensis Ab | Method and means for producing bronchorelaxation |
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