US10219707B2 - Device for measurement of pressure and administration of drugs in an aneurysm in a blood vessel - Google Patents

Device for measurement of pressure and administration of drugs in an aneurysm in a blood vessel Download PDF

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Publication number
US10219707B2
US10219707B2 US14/436,612 US201314436612A US10219707B2 US 10219707 B2 US10219707 B2 US 10219707B2 US 201314436612 A US201314436612 A US 201314436612A US 10219707 B2 US10219707 B2 US 10219707B2
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United States
Prior art keywords
hollow tube
aneurysmal
aneurysm
pressure
drugs
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Expired - Fee Related
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US14/436,612
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English (en)
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US20150257657A1 (en
Inventor
Zaza Alexandrovich Kavteladze
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
    • A61B5/02014—Determining aneurysm
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6862—Stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0247—Pressure sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/88—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir

Definitions

  • the invention relates to medicine, in particular, to vascular and endovascular surgery.
  • a stent-graft providing internal isolation of an aneurysm in a blood vessel is known (see U.S. Pat. No. 5,716,365, A61F, 1998).
  • a disadvantage of the stent-graft is in impossibility of assessing the condition of an isolated aneurysmal sac after the graft implantation (in particular, impossibility of measuring of intra-aneurysm sac pressure and administering drugs, as far as necessary).
  • a device for measurement of pressure and for administration of drugs is known (see U.S. Pat. No. 5,037,403, A61M 25/00, 1991), wherein the device is made in the form of a catheter with side apertures. Said device is the closest technical solution in terms of the problem to be solved.
  • a disadvantage of the known technical solution is in impossibility of assessing the condition of an isolated space of an aneurysmal sac between the aneurysmal vessel wall and the wall of a stent-graft after the implantation of the latter.
  • the objective of the invention is to eliminate the above disadvantages and develop a device allowing assessment of the condition of an isolated space of an aneurysmal sac by measuring pressure and administering drugs to an aneurysm in a blood vessel after implantation of a stent-graft.
  • the objective is achieved by providing a device for measurement of pressure and for administration of drugs made in the form of a hollow tube with side apertures, the device being made of a shape-memory material—nitinol—that provides changing the shape of the tube when the latter is introduced into an aneurysm in a blood vessel and filling the entire interior space of the aneurysm at its circumference, and wherein the tube is adapted to be connected to a pressure-measuring sensor and to administer drugs through a detachable hollow tube.
  • FIGURE shows a general view of the claimed invention.
  • the device for measurement of pressure and for administration of drugs is made in the form of hollow tube 1 with side apertures 2 .
  • Hollow tube 1 is made of nitinol, i.e. a shape-memory material, and is adapted to be connected to a pressure-measuring sensor (not shown) and to administer drugs through detachable hollow tube 3 .
  • the device is used as follows:
  • an aneurysm in a blood vessel is diagnosed to determine its shape and size.
  • the shape and size of nitinol-made hollow tube 1 is specified on the basis of the diagnostic results, and then the tube is introduced into the aneurysm in the blood vessel by one of known methods.
  • the shape-memory material allows hollow tube 1 to fill the entire interior space of the aneurism at its circumference. After that a stent-graft is implanted by a known method.
  • Measurement of pressure and, if necessary, administration of drugs, for example Thrombovar, are performed through detachable hollow tube 3 disposed in the aneurysmal sac between the vessel wall and the wall of the stent-graft, by using side apertures 2 .
  • Hollow tube 3 is removed also by a known method.
  • the design of the device for measurement of pressure and for administration of drugs to an aneurysm in a blood vessel made in the form of a hollow tube having shape memory allows qualitative measurement of pressure and qualitative administration of drugs due to filling by the hollow tube the interior space of the aneurysm at its circumference.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Neurosurgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
US14/436,612 2012-10-18 2013-10-02 Device for measurement of pressure and administration of drugs in an aneurysm in a blood vessel Expired - Fee Related US10219707B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2012144358/14A RU2521833C2 (ru) 2012-10-18 2012-10-18 Устройство для измерения давления и введения лекарственных веществ в аневризму кровеносного сосуда
RU2012144358 2012-10-18
PCT/RU2013/000873 WO2014062089A1 (fr) 2012-10-18 2013-10-02 Dispositif de mesure de pression et d'introduction de substances médicamenteuses dans l'anévrisme d'un vaisseau sanguin

Publications (2)

Publication Number Publication Date
US20150257657A1 US20150257657A1 (en) 2015-09-17
US10219707B2 true US10219707B2 (en) 2019-03-05

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US14/436,612 Expired - Fee Related US10219707B2 (en) 2012-10-18 2013-10-02 Device for measurement of pressure and administration of drugs in an aneurysm in a blood vessel

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US (1) US10219707B2 (fr)
EP (1) EP2910184A4 (fr)
RU (1) RU2521833C2 (fr)
WO (1) WO2014062089A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2557418C1 (ru) * 2014-08-06 2015-07-20 Заза Александрович Кавтеладзе Устройство для измерения давления и введения лекарственных веществ в аневризму кровеносного сосуда
RU2633629C9 (ru) * 2016-07-22 2018-03-12 Заза Александрович Кавтеладзе Способ лечения аневризмы кровеносного сосуда (варианты)
RU2633470C9 (ru) * 2016-07-22 2018-03-12 Заза Александрович Кавтеладзе Способ лечения аневризмы кровеносного сосуда (варианты)
CA3135412A1 (fr) * 2019-04-03 2020-10-08 Canary Medical Switzerland Ag Fourniture de dispositifs medicaux a fonctionnalite de detection

Citations (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU260101A1 (ru) Р. Н. Грингоф, И. А. Саморуков , С. В. Татаринов Устройство для подачи жидкости в катетер
US5037403A (en) 1989-11-08 1991-08-06 Cordis Corporation Pigtail catheter with angled apertures
US5716365A (en) 1994-02-09 1998-02-10 Boston Scientific Technologies, Inc. Bifurcated endoluminal prosthesis
WO1998009583A2 (fr) 1996-09-06 1998-03-12 William Cook Europe A/S Ensemble d'insertion transluminale d'extenseur tubulaire et dispositif de greffe endovasculaire
US6360749B1 (en) 1998-10-09 2002-03-26 Swaminathan Jayaraman Modification of properties and geometry of heart tissue to influence heart function
WO2002058551A2 (fr) 2001-01-22 2002-08-01 Integrated Sensing Systems, Inc. Capteur capacitif de systeme microelectromecanique sans fil permettant de mesurer un parametre physiologique
US6840956B1 (en) 2000-03-10 2005-01-11 Remon Medical Technologies Ltd Systems and methods for deploying a biosensor with a stent graft
US20050187482A1 (en) * 2003-09-16 2005-08-25 O'brien David Implantable wireless sensor
WO2006055443A2 (fr) 2004-11-15 2006-05-26 Izex Technologies, Inc. Endoprotheses, greffons vasculaires et autres dispositifs medicaux implantables et instrumentes
WO2006058042A2 (fr) 2004-11-26 2006-06-01 Biomerix Corporation Dispositifs et procedes d'occlusion vasculaire
RU61120U1 (ru) 2006-10-13 2007-02-27 Закрытое акционерное общество "ААА-КОМПАНИ" Средство для эмболизации сосудов
US20070162106A1 (en) 2005-07-07 2007-07-12 Nellix, Inc. System and methods for endovascular aneurysm treatment
US20070168011A1 (en) * 2005-11-14 2007-07-19 Duke Fiduciary, Llc Detachable therapeutic material
US20070239261A1 (en) 2006-04-07 2007-10-11 Arani Bose Aneurysm occlusion system and method
US20080004692A1 (en) 2006-06-28 2008-01-03 Henson Michael R Dynamically adjustable vascular stent
US20080097297A1 (en) 2006-08-31 2008-04-24 Kelley Gregory S Medical device for local site-specific drug delivery
US20080234809A1 (en) 2007-03-23 2008-09-25 Medtronic Vascular, Inc. Stent Graft System With Injection Tube
WO2009048372A1 (fr) 2007-10-11 2009-04-16 Milux Holding Sa Dispositif, procédé et système permettant de contrôler et de traiter un anévrisme
WO2009132396A1 (fr) 2008-05-02 2009-11-05 Commonwealth Scientific And Industrial Research Organisation Procédé et appareil de détermination de pression de fluide
WO2010068467A1 (fr) 2008-11-25 2010-06-17 Attenuex Technologies, Inc. Implant avec milieu à pression de vapeur élevée
RU2009119849A (ru) 2009-05-25 2010-11-27 Федеральное государственное учреждение "Новосибирский научно-исследовательский институт патологии кровообращения имени академика Е. Способ интраоперационной диагностики нарушения коллатерального кровообращения в бассейне нижней брыжеечной и внутренних подвздошных артериях при аневризме инфраренального отдела брюшной аорты
US20110067778A1 (en) 2009-09-20 2011-03-24 Medtronic Vascular, Inc. Apparatus and Methods for Loading a Drug Eluting Medical Device
US20110230952A1 (en) * 2005-07-29 2011-09-22 Kassab Ghassan S Endoprosthesis assemblies and methods for using the same
US20120101510A1 (en) 2008-12-23 2012-04-26 Reverse Medical Corporation Systems And Methods For Removing Obstructive Matter From Body Lumens And Treating Vascular Defects
RU2011105185A (ru) 2011-02-11 2012-08-20 Общество с ограниченной ответственностью "АСТОР" (RU) Способ активной профилактики острых нарушений мозгового кровообращения эмбологенной природы и фильтрующий стент-графт для его осуществления по беляеву о.в.
RU2460500C1 (ru) 2011-03-28 2012-09-10 Сергей Викторович Соколов Устройство имплантата для сосудов человека и животных
US20130289690A1 (en) * 2011-11-01 2013-10-31 Hira V. Thapliyal Personalized prosthesis and methods of use

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU260101A1 (ru) Р. Н. Грингоф, И. А. Саморуков , С. В. Татаринов Устройство для подачи жидкости в катетер
US5037403A (en) 1989-11-08 1991-08-06 Cordis Corporation Pigtail catheter with angled apertures
US5716365A (en) 1994-02-09 1998-02-10 Boston Scientific Technologies, Inc. Bifurcated endoluminal prosthesis
RU2192810C2 (ru) 1996-09-06 2002-11-20 Вилльям Кук Юроп А/С Комплект для транслюминального введения трубчатого стента и эндоваскулярный трансплантат
WO1998009583A2 (fr) 1996-09-06 1998-03-12 William Cook Europe A/S Ensemble d'insertion transluminale d'extenseur tubulaire et dispositif de greffe endovasculaire
US6360749B1 (en) 1998-10-09 2002-03-26 Swaminathan Jayaraman Modification of properties and geometry of heart tissue to influence heart function
US6840956B1 (en) 2000-03-10 2005-01-11 Remon Medical Technologies Ltd Systems and methods for deploying a biosensor with a stent graft
WO2002058551A2 (fr) 2001-01-22 2002-08-01 Integrated Sensing Systems, Inc. Capteur capacitif de systeme microelectromecanique sans fil permettant de mesurer un parametre physiologique
US20050187482A1 (en) * 2003-09-16 2005-08-25 O'brien David Implantable wireless sensor
WO2006055443A2 (fr) 2004-11-15 2006-05-26 Izex Technologies, Inc. Endoprotheses, greffons vasculaires et autres dispositifs medicaux implantables et instrumentes
WO2006058042A2 (fr) 2004-11-26 2006-06-01 Biomerix Corporation Dispositifs et procedes d'occlusion vasculaire
US20070162106A1 (en) 2005-07-07 2007-07-12 Nellix, Inc. System and methods for endovascular aneurysm treatment
US20110230952A1 (en) * 2005-07-29 2011-09-22 Kassab Ghassan S Endoprosthesis assemblies and methods for using the same
US20070168011A1 (en) * 2005-11-14 2007-07-19 Duke Fiduciary, Llc Detachable therapeutic material
US20070239261A1 (en) 2006-04-07 2007-10-11 Arani Bose Aneurysm occlusion system and method
US20080004692A1 (en) 2006-06-28 2008-01-03 Henson Michael R Dynamically adjustable vascular stent
US20080097297A1 (en) 2006-08-31 2008-04-24 Kelley Gregory S Medical device for local site-specific drug delivery
RU61120U1 (ru) 2006-10-13 2007-02-27 Закрытое акционерное общество "ААА-КОМПАНИ" Средство для эмболизации сосудов
US20080234809A1 (en) 2007-03-23 2008-09-25 Medtronic Vascular, Inc. Stent Graft System With Injection Tube
WO2009048372A1 (fr) 2007-10-11 2009-04-16 Milux Holding Sa Dispositif, procédé et système permettant de contrôler et de traiter un anévrisme
WO2009132396A1 (fr) 2008-05-02 2009-11-05 Commonwealth Scientific And Industrial Research Organisation Procédé et appareil de détermination de pression de fluide
WO2010068467A1 (fr) 2008-11-25 2010-06-17 Attenuex Technologies, Inc. Implant avec milieu à pression de vapeur élevée
US20120101510A1 (en) 2008-12-23 2012-04-26 Reverse Medical Corporation Systems And Methods For Removing Obstructive Matter From Body Lumens And Treating Vascular Defects
RU2009119849A (ru) 2009-05-25 2010-11-27 Федеральное государственное учреждение "Новосибирский научно-исследовательский институт патологии кровообращения имени академика Е. Способ интраоперационной диагностики нарушения коллатерального кровообращения в бассейне нижней брыжеечной и внутренних подвздошных артериях при аневризме инфраренального отдела брюшной аорты
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RU2011105185A (ru) 2011-02-11 2012-08-20 Общество с ограниченной ответственностью "АСТОР" (RU) Способ активной профилактики острых нарушений мозгового кровообращения эмбологенной природы и фильтрующий стент-графт для его осуществления по беляеву о.в.
RU2462197C1 (ru) 2011-02-11 2012-09-27 Общество с ограниченной ответственностью "АСТОР" Способ активной профилактики острых нарушений мозгового кровообращения эмбологенной природы и фильтрующий стент-графт для его осуществления по беляеву о.в.
RU2460500C1 (ru) 2011-03-28 2012-09-10 Сергей Викторович Соколов Устройство имплантата для сосудов человека и животных
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Jan. 16, 2014 (WO) International Search Report-International application PCT/RU2013/000873.
Jan. 16, 2014 (WO) International Search Report—International application PCT/RU2013/000873.
May 11, 2016-(EP) Supplementary European Search Report-App 13847821.
May 11, 2016—(EP) Supplementary European Search Report—App 13847821.

Also Published As

Publication number Publication date
WO2014062089A1 (fr) 2014-04-24
RU2521833C2 (ru) 2014-07-10
EP2910184A1 (fr) 2015-08-26
US20150257657A1 (en) 2015-09-17
EP2910184A4 (fr) 2016-06-15
RU2012144358A (ru) 2014-04-27

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