UA99913C2 - Способ получения 6-{4-[3-((r)-2-метилпирролидин-1-ил)пропокси]фенил}-2н-пиридазин-3-она и его солей - Google Patents
Способ получения 6-{4-[3-((r)-2-метилпирролидин-1-ил)пропокси]фенил}-2н-пиридазин-3-она и его солейInfo
- Publication number
- UA99913C2 UA99913C2 UAA200912476A UAA200912476A UA99913C2 UA 99913 C2 UA99913 C2 UA 99913C2 UA A200912476 A UAA200912476 A UA A200912476A UA A200912476 A UAA200912476 A UA A200912476A UA 99913 C2 UA99913 C2 UA 99913C2
- Authority
- UA
- Ukraine
- Prior art keywords
- methylpyrrolidine
- pyridazin
- propoxy
- phenyl
- salts
- Prior art date
Links
- XUKROCVZGZNGSI-CQSZACIVSA-N irdabisant Chemical compound C[C@@H]1CCCN1CCCOC1=CC=C(C2=NNC(=O)C=C2)C=C1 XUKROCVZGZNGSI-CQSZACIVSA-N 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000010963 scalable process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92735607P | 2007-05-03 | 2007-05-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA99913C2 true UA99913C2 (ru) | 2012-10-25 |
Family
ID=39688886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200912476A UA99913C2 (ru) | 2007-05-03 | 2008-05-02 | Способ получения 6-{4-[3-((r)-2-метилпирролидин-1-ил)пропокси]фенил}-2н-пиридазин-3-она и его солей |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP2152669A1 (esLanguage) |
| JP (1) | JP5698887B2 (esLanguage) |
| KR (1) | KR20100017565A (esLanguage) |
| CN (1) | CN101679237A (esLanguage) |
| AU (1) | AU2008248168B2 (esLanguage) |
| BR (1) | BRPI0810330A2 (esLanguage) |
| CA (1) | CA2686033A1 (esLanguage) |
| EA (1) | EA019031B1 (esLanguage) |
| IL (1) | IL201627A (esLanguage) |
| MX (1) | MX2009011787A (esLanguage) |
| NZ (1) | NZ580948A (esLanguage) |
| UA (1) | UA99913C2 (esLanguage) |
| WO (1) | WO2008137087A1 (esLanguage) |
| ZA (1) | ZA200907643B (esLanguage) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY148634A (en) | 2006-07-25 | 2013-05-15 | Cephalon Inc | Pyridazinone derivatives |
| US8383657B2 (en) | 2007-12-21 | 2013-02-26 | Abbott Laboratories | Thiazolylidine urea and amide derivatives and methods of use thereof |
| JP5539230B2 (ja) * | 2008-01-30 | 2014-07-02 | セファロン、インク． | ヒスタミンｈ３アンタゴニスト活性を有する置換ピリダジン誘導体 |
| EP3237408B1 (en) * | 2014-12-23 | 2018-10-31 | Cephalon, Inc. | Methods for preparing fused bicyclic 2, 4-diaminopyrimidine derivatives |
| BR112021003061A2 (pt) * | 2018-09-07 | 2021-05-11 | Sanofi | processo para a preparação do 6-(2,4-diclorofenil)-5-[4-[(3s)-1-(3-fluoropropil)pirrolidin-3-il]oxifenil]-8,9-dihidro-7h-benzo[7]anuleno-2-carboxilato de metila |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3329974A1 (de) | 1983-08-19 | 1985-02-28 | Bayer Ag, 5090 Leverkusen | Herstellung von hydrierten nitrilkautschuken |
| DE3433392A1 (de) | 1984-09-12 | 1986-03-20 | Bayer Ag, 5090 Leverkusen | Hydrierung nitrilgruppenhaltiger ungesaettigter polymerer |
| FR2714849B1 (fr) | 1994-01-13 | 1996-04-05 | Inst Francais Du Petrole | Procédé de préparation d'un catalyseur d'hydrogénation soluble en phase liquide organique. |
| DE4403479A1 (de) | 1994-02-04 | 1995-08-10 | Basf Ag | Verfahren zur Herstellung von Hydroxylammoniumsalzen |
| WO2004024707A2 (en) * | 2002-09-16 | 2004-03-25 | Abbott Laboratories | Process for preparing amine type substituted benzofurans |
| US7153889B2 (en) | 2002-11-12 | 2006-12-26 | Abbott Laboratories | Bicyclic-substituted amines as histamine-3 receptor ligands |
| WO2005085307A1 (ja) | 2004-03-08 | 2005-09-15 | Japan Science And Technology Agency | 高分子担持金属クラスター組成物 |
| US7145005B2 (en) | 2004-05-12 | 2006-12-05 | Abbott Laboratories | 2-(6-{2-[(2R)-2-Methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation |
| BRPI0511778A (pt) | 2004-06-02 | 2008-01-15 | Hoffmann La Roche | derivados da naftalina úteis como ligantes do receptor 3 da histamina |
| WO2006059778A1 (ja) | 2004-12-01 | 2006-06-08 | Banyu Pharmaceutical Co., Ltd. | 置換ピリドン誘導体 |
| CA2592353A1 (en) | 2004-12-17 | 2006-06-22 | Janssen Pharmaceutica, N.V. | Tetrahydroisoquinoline compounds for treatment of cns disorders |
| CN101107231A (zh) | 2005-01-21 | 2008-01-16 | 先灵公司 | 用作组胺h3拮抗剂的咪唑和苯并咪唑衍生物 |
| WO2006103045A1 (en) | 2005-03-31 | 2006-10-05 | Ucb Pharma S.A. | Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses |
| GB0514812D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
| CN101296902A (zh) | 2005-10-27 | 2008-10-29 | Ucb医药有限公司 | 包含内酰胺或内酰胺衍生部分的化合物、制备它们的方法和它们的用途 |
| EP1988777B1 (en) | 2006-02-09 | 2011-09-21 | Athersys, Inc. | Pyrazoles for the treatment of obesity and other cns disorders |
| WO2007099423A1 (en) | 2006-03-02 | 2007-09-07 | Pfizer Products Inc. | 1-pyrrolidine indane derivatives as histamine-3 receptor antagonists |
| US20090163482A1 (en) | 2006-03-13 | 2009-06-25 | Mchardy Stanton Furst | Tetralines antagonists of the h-3 receptor |
| WO2008005338A1 (en) | 2006-06-29 | 2008-01-10 | Arena Pharmaceuticals, Inc. | Modulators of the histamine h3-receptor useful for the treatment of disorders related thereto |
| MY148634A (en) | 2006-07-25 | 2013-05-15 | Cephalon Inc | Pyridazinone derivatives |
-
2008
- 2008-05-02 UA UAA200912476A patent/UA99913C2/ru unknown
- 2008-05-02 JP JP2010507416A patent/JP5698887B2/ja not_active Expired - Fee Related
- 2008-05-02 BR BRPI0810330-5A2A patent/BRPI0810330A2/pt not_active IP Right Cessation
- 2008-05-02 NZ NZ580948A patent/NZ580948A/en not_active IP Right Cessation
- 2008-05-02 KR KR1020097025141A patent/KR20100017565A/ko not_active Ceased
- 2008-05-02 AU AU2008248168A patent/AU2008248168B2/en not_active Ceased
- 2008-05-02 WO PCT/US2008/005702 patent/WO2008137087A1/en not_active Ceased
- 2008-05-02 CA CA002686033A patent/CA2686033A1/en not_active Abandoned
- 2008-05-02 EP EP08754205A patent/EP2152669A1/en not_active Withdrawn
- 2008-05-02 MX MX2009011787A patent/MX2009011787A/es active IP Right Grant
- 2008-05-02 CN CN200880021225A patent/CN101679237A/zh active Pending
- 2008-05-02 EA EA200971019A patent/EA019031B1/ru not_active IP Right Cessation
-
2009
- 2009-10-19 IL IL201627A patent/IL201627A/en not_active IP Right Cessation
- 2009-10-30 ZA ZA2009/07643A patent/ZA200907643B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2009011787A (es) | 2009-11-13 |
| WO2008137087A1 (en) | 2008-11-13 |
| JP5698887B2 (ja) | 2015-04-08 |
| ZA200907643B (en) | 2014-03-26 |
| EA200971019A1 (ru) | 2010-04-30 |
| CN101679237A (zh) | 2010-03-24 |
| EA019031B1 (ru) | 2013-12-30 |
| IL201627A0 (en) | 2010-05-31 |
| IL201627A (en) | 2014-06-30 |
| BRPI0810330A2 (pt) | 2014-10-14 |
| KR20100017565A (ko) | 2010-02-16 |
| NZ580948A (en) | 2011-04-29 |
| JP2010526142A (ja) | 2010-07-29 |
| EP2152669A1 (en) | 2010-02-17 |
| CA2686033A1 (en) | 2008-11-13 |
| AU2008248168B2 (en) | 2013-03-21 |
| AU2008248168A1 (en) | 2008-11-13 |
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