UA99913C2 - Process for preparing 6-{4-[3-((r)-2-methylpyrrolidine-1-yl)-propoxy]-phenyl}-2h-pyridazin-3-one and salts thereof - Google Patents

Process for preparing 6-{4-[3-((r)-2-methylpyrrolidine-1-yl)-propoxy]-phenyl}-2h-pyridazin-3-one and salts thereof

Info

Publication number
UA99913C2
UA99913C2 UAA200912476A UAA200912476A UA99913C2 UA 99913 C2 UA99913 C2 UA 99913C2 UA A200912476 A UAA200912476 A UA A200912476A UA A200912476 A UAA200912476 A UA A200912476A UA 99913 C2 UA99913 C2 UA 99913C2
Authority
UA
Ukraine
Prior art keywords
methylpyrrolidine
pyridazin
propoxy
phenyl
salts
Prior art date
Application number
UAA200912476A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Майкл Кристи
Джозеф Дж. Петрейтис
Original Assignee
Сефалон, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сефалон, Инк. filed Critical Сефалон, Инк.
Publication of UA99913C2 publication Critical patent/UA99913C2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)

Abstract

The present invention provides a short, safe, inexpensive, commercially scalable process for preparing 6-{4-[3-((r)-2-methylpyrrolidine-1-yl)-propoxy]-phenyl}-2H-pyridazin-3-one and salts thereof.
UAA200912476A 2007-05-03 2008-05-02 Process for preparing 6-{4-[3-((r)-2-methylpyrrolidine-1-yl)-propoxy]-phenyl}-2h-pyridazin-3-one and salts thereof UA99913C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92735607P 2007-05-03 2007-05-03

Publications (1)

Publication Number Publication Date
UA99913C2 true UA99913C2 (en) 2012-10-25

Family

ID=39688886

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200912476A UA99913C2 (en) 2007-05-03 2008-05-02 Process for preparing 6-{4-[3-((r)-2-methylpyrrolidine-1-yl)-propoxy]-phenyl}-2h-pyridazin-3-one and salts thereof

Country Status (14)

Country Link
EP (1) EP2152669A1 (en)
JP (1) JP5698887B2 (en)
KR (1) KR20100017565A (en)
CN (1) CN101679237A (en)
AU (1) AU2008248168B2 (en)
BR (1) BRPI0810330A2 (en)
CA (1) CA2686033A1 (en)
EA (1) EA019031B1 (en)
IL (1) IL201627A (en)
MX (1) MX2009011787A (en)
NZ (1) NZ580948A (en)
UA (1) UA99913C2 (en)
WO (1) WO2008137087A1 (en)
ZA (1) ZA200907643B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY148634A (en) 2006-07-25 2013-05-15 Cephalon Inc Pyridazinone derivatives
US8383657B2 (en) 2007-12-21 2013-02-26 Abbott Laboratories Thiazolylidine urea and amide derivatives and methods of use thereof
EP2252593B1 (en) * 2008-01-30 2014-04-23 Cephalon, Inc. Substituted pyridazine derivatives which have histamine h3 antagonist activity
ES2707123T3 (en) * 2014-12-23 2019-04-02 Cephalon Inc Methods for the preparation of fused bicyclic 2, 4-diaminopyrimidine derivatives

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3329974A1 (en) 1983-08-19 1985-02-28 Bayer Ag, 5090 Leverkusen MANUFACTURE OF HYDRATED NITRILE RUBBER
DE3433392A1 (en) 1984-09-12 1986-03-20 Bayer Ag, 5090 Leverkusen HYDROGENATION OF UNSATURATED POLYMER WITH NITRILE GROUPS
FR2714849B1 (en) 1994-01-13 1996-04-05 Inst Francais Du Petrole Process for the preparation of a hydrogenation catalyst soluble in the organic liquid phase.
DE4403479A1 (en) 1994-02-04 1995-08-10 Basf Ag Process for the preparation of hydroxylammonium salts
WO2004024707A2 (en) * 2002-09-16 2004-03-25 Abbott Laboratories Process for preparing amine type substituted benzofurans
US7153889B2 (en) 2002-11-12 2006-12-26 Abbott Laboratories Bicyclic-substituted amines as histamine-3 receptor ligands
JP5055525B2 (en) 2004-03-08 2012-10-24 独立行政法人科学技術振興機構 Polymer-supported metal cluster composition
US7145005B2 (en) 2004-05-12 2006-12-05 Abbott Laboratories 2-(6-{2-[(2R)-2-Methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation
ATE383857T1 (en) 2004-06-02 2008-02-15 Hoffmann La Roche NAPHTHALENE DERIVATIVES USABLE AS HISTAMINE-3 RECEPTOR LIGANDS
AU2005310467B2 (en) 2004-12-01 2011-06-23 Msd K.K. Substituted pyridone derivative
CN101128432A (en) 2004-12-17 2008-02-20 詹森药业有限公司 Tetrahydroisoquinoline compounds for treatment of cns disorders
CA2595157A1 (en) 2005-01-21 2006-07-27 Schering Corporation Imidazole and benzimidazole derivatives useful as histamine h3 antagonists
EP1866293A1 (en) 2005-03-31 2007-12-19 UCB Pharma, S.A. Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses
GB0514812D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
EP1943217A1 (en) 2005-10-27 2008-07-16 UCB Pharma, S.A. Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses
ATE525072T1 (en) 2006-02-09 2011-10-15 Athersys Inc PYRAZOLES FOR THE TREATMENT OF OBESITY AND OTHER CNS DISEASES
WO2007099423A1 (en) 2006-03-02 2007-09-07 Pfizer Products Inc. 1-pyrrolidine indane derivatives as histamine-3 receptor antagonists
JP2009539762A (en) 2006-03-13 2009-11-19 ファイザー・プロダクツ・インク Tetralin antagonist of H3 receptor
WO2008005338A1 (en) 2006-06-29 2008-01-10 Arena Pharmaceuticals, Inc. Modulators of the histamine h3-receptor useful for the treatment of disorders related thereto
MY148634A (en) 2006-07-25 2013-05-15 Cephalon Inc Pyridazinone derivatives

Also Published As

Publication number Publication date
NZ580948A (en) 2011-04-29
BRPI0810330A2 (en) 2014-10-14
AU2008248168A1 (en) 2008-11-13
CA2686033A1 (en) 2008-11-13
IL201627A (en) 2014-06-30
EA200971019A1 (en) 2010-04-30
EA019031B1 (en) 2013-12-30
AU2008248168B2 (en) 2013-03-21
JP2010526142A (en) 2010-07-29
WO2008137087A1 (en) 2008-11-13
CN101679237A (en) 2010-03-24
MX2009011787A (en) 2009-11-13
IL201627A0 (en) 2010-05-31
JP5698887B2 (en) 2015-04-08
KR20100017565A (en) 2010-02-16
ZA200907643B (en) 2014-03-26
EP2152669A1 (en) 2010-02-17

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