UA93188C2 - Эффективные олигонуклеотиды lna для ингибирования экспрессии hif-1a - Google Patents

Эффективные олигонуклеотиды lna для ингибирования экспрессии hif-1a

Info

Publication number
UA93188C2
UA93188C2 UAA200706383A UAA200706383A UA93188C2 UA 93188 C2 UA93188 C2 UA 93188C2 UA A200706383 A UAA200706383 A UA A200706383A UA A200706383 A UAA200706383 A UA A200706383A UA 93188 C2 UA93188 C2 UA 93188C2
Authority
UA
Ukraine
Prior art keywords
lna
hif
expression
deoxynucleotide
oxy
Prior art date
Application number
UAA200706383A
Other languages
English (en)
Ukrainian (uk)
Inventor
Франк Винтер Расмуссен
Майкен Вестергор
Хенрик Фрюденлунд Хансен
Шарлот Альбек Tpy
Original Assignee
Сантарис Фарма A/C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сантарис Фарма A/C filed Critical Сантарис Фарма A/C
Publication of UA93188C2 publication Critical patent/UA93188C2/ru

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
UAA200706383A 2004-11-09 2005-11-09 Эффективные олигонуклеотиды lna для ингибирования экспрессии hif-1a UA93188C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62656304P 2004-11-09 2004-11-09

Publications (1)

Publication Number Publication Date
UA93188C2 true UA93188C2 (ru) 2011-01-25

Family

ID=38880909

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200706383A UA93188C2 (ru) 2004-11-09 2005-11-09 Эффективные олигонуклеотиды lna для ингибирования экспрессии hif-1a

Country Status (4)

Country Link
CN (1) CN101068826B (ru)
ES (1) ES2348247T3 (ru)
UA (1) UA93188C2 (ru)
ZA (1) ZA200704253B (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104586794A (zh) * 2014-12-25 2015-05-06 海南卫康制药(潜山)有限公司 一种氨鲁米特组合物冻干片及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE037352T2 (hu) * 2002-04-05 2018-08-28 Roche Innovation Ct Copenhagen As A HIF-1alfa expresszálódását módosító oligomer vegyületek

Also Published As

Publication number Publication date
ZA200704253B (en) 2008-09-25
ES2348247T3 (es) 2010-12-02
CN101068826A (zh) 2007-11-07
CN101068826B (zh) 2011-11-16

Similar Documents

Publication Publication Date Title
WO2006050734A3 (en) Potent lna oligonucleotides for the inhibition of hif-1a expression
HK1244504A1 (zh) 反義設計
IL176320A0 (en) Oligomeric compounds for the modulation of bcl-2
EP1604010A4 (en) COMPOSITIONS AND METHODS FOR INHIBITING ICAM-1 GENE BY LOW INHIBITION RNA
WO2003100017A3 (en) Oligonucleotides having modified nucleoside units
EP2345718A3 (en) Compositions and methods for siRNA inhibition of angiogenesis
IL300119A (en) Oligonucleotides to induce paternal UBE3A expression
EP2213736A3 (de) Verfahren zur Hemmung der Expression eines Zielgens und Medikament zur Therapie einer Tumorerkrankung
DE69934227D1 (de) Auf beta-arabinose, und dessen analogen, basierte antisense oligonukleotide
EP1750771A4 (en) PANCREATIC ILOT MICRO-RNA AND METHODS OF INHIBITING THE SAME
WO2004044133A3 (en) Modified oligonucleotides for use in rna interference
WO2004094606A3 (en) COMPOSITIONS AND METHODS FOR siRNA INHIBITION OF ANGIOPOIETIN 1 AND 2 AND THEIR RECEPTOR TIE2
MX2020009765A (es) Oligonucleotido antisentido reducido en toxicidad.
AU2014208251B2 (en) Carbohydrate conjugates as delivery agents for oligonucleotides
WO2007117121A3 (en) Gene therapy for cancer using small interfering rna specific to ant2 and a method to overcome tolerance to antitumor agent
HK1113318A1 (en) Oligonucleotide and compositions comprising the same for treating b cell neoplasm
MX2021007932A (es) Molecula oligomerica de acido nucleico y uso de esta.
UA93188C2 (ru) Эффективные олигонуклеотиды lna для ингибирования экспрессии hif-1a
WO2008001219A3 (en) Cancer therapy using bcl-xl-specific sina
Peyman et al. Nuclease stability as dominant factor in the antiviral activity of oligonucleotides directed against HSV-1 IE110
DE10346721A1 (de) Oligonukleotide, diese enthaltende Mittel und deren Verwendung
ATE428786T1 (de) Antisense-oligonukleotid mit antikrebsaktivität
WO2005026359A3 (en) The use of eukaryotic genes affecting spindle formation or microtubule function during cell division for diagnosis and treatment of proliferative diseases
IL149640A0 (en) Antisense oligonucleotides
WO2022032017A3 (en) Human xist antisense oligonucleotides for x reactivation therapy