UA87109C2 - USE OF HIF PROLYLHYDROXYLASE INHIBITOR FOR TREATMENT OF ANEMIAS AND iron deficiency - Google Patents
USE OF HIF PROLYLHYDROXYLASE INHIBITOR FOR TREATMENT OF ANEMIAS AND iron deficiencyInfo
- Publication number
- UA87109C2 UA87109C2 UAA200600150A UAA200600150A UA87109C2 UA 87109 C2 UA87109 C2 UA 87109C2 UA A200600150 A UAA200600150 A UA A200600150A UA A200600150 A UAA200600150 A UA A200600150A UA 87109 C2 UA87109 C2 UA 87109C2
- Authority
- UA
- Ukraine
- Prior art keywords
- prolylhydroxylase
- inhibitor
- treatment
- anemia
- iron deficiency
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to the methods for treatment or prevention of anemia caused by chronic disease, iron deficiency, microcytosis or microcytic anemia, anemia, connected with cytokine activity, anemia, which is difficult to treat by erythropoietin (ЕРО), which is administered exogenously using efficient amount ofHIF prolylhydroxylase inhibitor, which represents the structural mimetic of 2-oxoglutarate.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47670403P | 2003-06-06 | 2003-06-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
UA87109C2 true UA87109C2 (en) | 2009-06-25 |
Family
ID=36908152
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200600150A UA87109C2 (en) | 2003-06-06 | 2004-06-04 | USE OF HIF PROLYLHYDROXYLASE INHIBITOR FOR TREATMENT OF ANEMIAS AND iron deficiency |
Country Status (4)
Country | Link |
---|---|
CN (1) | CN1816327B (en) |
NO (1) | NO20171470A1 (en) |
UA (1) | UA87109C2 (en) |
ZA (1) | ZA200509279B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2334682B1 (en) * | 2008-08-20 | 2017-10-04 | Fibrogen, Inc. | Pyrrolo [ 1, 2 -b] pyridazine derivatives and their use as hif modulators |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60037813T2 (en) * | 1999-06-04 | 2009-01-15 | Dana-Farber Cancer Institute, Inc., Boston | IDENTIFICATION OF SUBSTANCES THAT MODIFY TRANSCRIPTIONAL ANSWERS TO HYPOXIA |
-
2004
- 2004-06-04 ZA ZA200509279A patent/ZA200509279B/en unknown
- 2004-06-04 CN CN2004800193070A patent/CN1816327B/en not_active Expired - Lifetime
- 2004-06-04 UA UAA200600150A patent/UA87109C2/en unknown
-
2017
- 2017-09-12 NO NO20171470A patent/NO20171470A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO20171470A1 (en) | 2006-01-06 |
CN1816327A (en) | 2006-08-09 |
ZA200509279B (en) | 2007-11-28 |
CN1816327B (en) | 2010-09-08 |
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