ZA200509279B - Use of hif alpha stabilizers for enhancing erythropoiesis - Google Patents

Use of hif alpha stabilizers for enhancing erythropoiesis

Info

Publication number
ZA200509279B
ZA200509279B ZA200509279A ZA200509279A ZA200509279B ZA 200509279 B ZA200509279 B ZA 200509279B ZA 200509279 A ZA200509279 A ZA 200509279A ZA 200509279 A ZA200509279 A ZA 200509279A ZA 200509279 B ZA200509279 B ZA 200509279B
Authority
ZA
South Africa
Prior art keywords
enhancing erythropoiesis
hif alpha
alpha stabilizers
stabilizers
hif
Prior art date
Application number
ZA200509279A
Inventor
Stephen J Klaus
Christopher J Molineaux
Thomas B Neff
Guenzler-Pukall Volkmar
Lansetmo Parobok Ingrid
Todd W Seeley
Robert C Stephenson
Original Assignee
Fibrogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fibrogen Inc filed Critical Fibrogen Inc
Publication of ZA200509279B publication Critical patent/ZA200509279B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/40Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200509279A 2003-06-06 2004-06-04 Use of hif alpha stabilizers for enhancing erythropoiesis ZA200509279B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47670403P 2003-06-06 2003-06-06

Publications (1)

Publication Number Publication Date
ZA200509279B true ZA200509279B (en) 2007-11-28

Family

ID=36908152

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200509279A ZA200509279B (en) 2003-06-06 2004-06-04 Use of hif alpha stabilizers for enhancing erythropoiesis

Country Status (4)

Country Link
CN (1) CN1816327B (en)
NO (1) NO20171470A1 (en)
UA (1) UA87109C2 (en)
ZA (1) ZA200509279B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102264740B (en) * 2008-08-20 2014-10-15 菲布罗根有限公司 Pyrrolo [ 1, 2 -b] pyridazine derivatives and their use as hif modulators

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1198255B1 (en) * 1999-06-04 2008-01-16 Dana-Farber Cancer Institute, Inc. Identification of compounds that modify transcriptional responses to hypoxia

Also Published As

Publication number Publication date
CN1816327A (en) 2006-08-09
UA87109C2 (en) 2009-06-25
CN1816327B (en) 2010-09-08
NO20171470A1 (en) 2006-01-06

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