UA83500C2 - Застосування дефібротиду як протипухлинного агента самостійно або в поєднанні з іншими протипухлинними агентами - Google Patents

Застосування дефібротиду як протипухлинного агента самостійно або в поєднанні з іншими протипухлинними агентами Download PDF

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Publication number
UA83500C2
UA83500C2 UAA200602374A UAA200602374A UA83500C2 UA 83500 C2 UA83500 C2 UA 83500C2 UA A200602374 A UAA200602374 A UA A200602374A UA A200602374 A UAA200602374 A UA A200602374A UA 83500 C2 UA83500 C2 UA 83500C2
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UA
Ukraine
Prior art keywords
oei
azor
miyza
abai
kytyza
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UAA200602374A
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English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Лаура Ирис Ферро
Массимо Якобелли
Пол Ричардсон
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Джентиум Спа
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of UA83500C2 publication Critical patent/UA83500C2/uk

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
UAA200602374A 2003-09-05 2004-08-27 Застосування дефібротиду як протипухлинного агента самостійно або в поєднанні з іншими протипухлинними агентами UA83500C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT001714A ITMI20031714A1 (it) 2003-09-05 2003-09-05 Formazioni ad azione antitumorale.
US53934404P 2004-01-28 2004-01-28
PCT/EP2004/009723 WO2005023273A1 (en) 2003-09-05 2004-08-27 Anti-tumor formulations comprising defibrotide alone or in combination with other anti-tumor agents

Publications (1)

Publication Number Publication Date
UA83500C2 true UA83500C2 (uk) 2008-07-25

Family

ID=37064585

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200602374A UA83500C2 (uk) 2003-09-05 2004-08-27 Застосування дефібротиду як протипухлинного агента самостійно або в поєднанні з іншими протипухлинними агентами

Country Status (23)

Country Link
US (2) US8551967B2 (https=)
EP (1) EP1660100B1 (https=)
JP (1) JP4671962B2 (https=)
KR (1) KR20060061367A (https=)
CN (1) CN100490820C (https=)
AT (1) ATE399558T1 (https=)
AU (1) AU2004269896B2 (https=)
BR (1) BRPI0414114A (https=)
CA (1) CA2537226C (https=)
DE (1) DE602004014787D1 (https=)
DK (1) DK1660100T3 (https=)
ES (1) ES2308223T3 (https=)
IL (1) IL173785A0 (https=)
IS (1) IS8334A (https=)
IT (1) ITMI20031714A1 (https=)
MX (1) MXPA06002489A (https=)
NO (1) NO20061402L (https=)
PT (1) PT1660100E (https=)
RS (1) RS20060154A (https=)
RU (1) RU2348413C2 (https=)
UA (1) UA83500C2 (https=)
WO (1) WO2005023273A1 (https=)
ZA (1) ZA200601852B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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WO2006094916A1 (en) * 2005-03-03 2006-09-14 Gentium Spa Defibrotide and/or oligodeoxyribonucleotides for treating angiogenesis-dependent tumors
EP1872787A1 (en) * 2006-06-27 2008-01-02 Gentium S.p.A. Use of defibrotide for the inhibition of heparanase
EP2103689A1 (en) * 2008-03-19 2009-09-23 Gentium S.p.A. Synthetic phosphodiester oligonucleotides and therapeutical uses thereof
AU2010363814B2 (en) 2010-11-12 2016-05-19 Gentium S.R.L. Defibrotide for use in prophylaxis and/or treatment of Graft versus Host Disease (GVHD).
CN110079580B (zh) 2012-06-22 2022-12-06 真蒂奥姆责任有限公司 用于测定去纤维蛋白多核苷酸的生物活性的基于优球蛋白的方法
EP3026122A1 (en) 2014-11-27 2016-06-01 Gentium S.p.A. Cellular-based method for determining the potency of defibrotide
US10380734B2 (en) * 2017-02-27 2019-08-13 Aniket Bharat Parikh System, method and computer program product for security analysis of jewelry items
JP2020530004A (ja) * 2017-08-03 2020-10-15 ジャズ ファーマシューティカルズ アイルランド リミテッド 核酸を高濃度で含む製剤
CN112236149A (zh) 2018-04-12 2021-01-15 贾兹制药公司 用于预防和治疗细胞因子释放综合征和与免疫耗竭相关的神经毒性的去纤苷
WO2020118165A1 (en) 2018-12-07 2020-06-11 Jazz Pharmaceuticals Ireland Limited Subcutaneous delivery of high concentration formulations
EP4110287A1 (en) 2020-02-28 2023-01-04 Jazz Pharmaceuticals Ireland Limited Delivery of low viscosity formulations
TW202308659A (zh) 2021-05-06 2023-03-01 愛爾蘭商爵士製藥愛爾蘭有限責任公司 用於急性呼吸窘迫症候群之治療及預防的去纖維蛋白多核苷酸

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IT1043823B (it) 1970-11-03 1980-02-29 Prephar Procedimento per l estrazione di acidi nucleici da organi animali
US3899481A (en) 1970-11-03 1975-08-12 Crinos Industria Farmaco Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs
US4853221A (en) * 1980-11-13 1989-08-01 Warner-Lambert Company Method for treating non-small cell lung cancer, head and neck cancers and breast cancer
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EP1872787A1 (en) 2006-06-27 2008-01-02 Gentium S.p.A. Use of defibrotide for the inhibition of heparanase
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Also Published As

Publication number Publication date
ITMI20031714A1 (it) 2005-03-06
WO2005023273A1 (en) 2005-03-17
CN1845746A (zh) 2006-10-11
IS8334A (is) 2006-02-28
RU2348413C2 (ru) 2009-03-10
CN100490820C (zh) 2009-05-27
JP2007504194A (ja) 2007-03-01
DE602004014787D1 (de) 2008-08-14
US20140005256A1 (en) 2014-01-02
MXPA06002489A (es) 2006-06-20
RU2006109210A (ru) 2007-10-10
ES2308223T3 (es) 2008-12-01
US20060211646A1 (en) 2006-09-21
NO20061402L (no) 2006-03-28
CA2537226C (en) 2016-05-03
JP4671962B2 (ja) 2011-04-20
CA2537226A1 (en) 2005-03-17
US8551967B2 (en) 2013-10-08
KR20060061367A (ko) 2006-06-07
EP1660100A1 (en) 2006-05-31
AU2004269896A1 (en) 2005-03-17
ZA200601852B (en) 2007-06-27
IL173785A0 (en) 2006-07-05
BRPI0414114A (pt) 2006-10-31
PT1660100E (pt) 2008-10-14
DK1660100T3 (da) 2008-11-10
RS20060154A (sr) 2008-08-07
AU2004269896B2 (en) 2009-11-19
EP1660100B1 (en) 2008-07-02
ATE399558T1 (de) 2008-07-15

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